The Chemical Biology and Drug Development (CBDD) Terminology is a set of terms used in design, development, and description of drug substances, mainly but not exclusively pertaining to the chemistry (including chemical reactions) of small molecules and polymers. The terminology is intended to support the chemoinformatics community's effort to develop conceptual models for describing modern drug design such as performed by the NCI Computer-Aided Drug Design (CADD) Group, part of the NCI Chemical Biology Laboratory and collaborators at NIH, academia, and other government agencies.
There are two CBDD terminology subsets, one focused on chemical processes (CBDD Process Terminology) and one focused on chemical structures (CBDD Structure Terminology). These subsets are available for download from this NCI EVS ftp site in two formats:
CBDD_Process_Terminology.xls (Microsoft Excel 2003)*
CBDD_Process_Terminology.txt (Tab-delimited text)
CBDD_Structure_Terminology.xls (Microsoft Excel 2003)*
CBDD_Structure_Terminology.txt (Tab-delimited text)
| Spreadsheet Column | Content Description |
|---|---|
| Subset Code | The NCI Thesaurus (NCIt) concept code attached to the CBDD concept. NCIt Codes are unique strings that begin with a C and are followed by a series of digits. |
| Subset Name | The name of the terminology set. |
| Concept Code | The NCI Thesaurus (NCIt) concept code attached to the concept. |
| NCIt Preferred Term | The preferred term chosen by the NCIt staff that unambiguously describes the concept. |
| CBDD Preferred Term | The preferred term chosen by CBDD for the concept. |
| CBDD Synonym(s) | Terms chosen by CBDD that are synonymous with the Preferred Term. |
| NCI Definition | A text definition of the term created by subject matter experts at the NCIt. |
| Semantic Type | A categorization of the type of concept in the context of the UMLS semantic network. |
Also included on the NCI EVS ftp site are the following additional files: