A C198975 UBERON Terminology C12396 Adrenal Cortex The outer region of the adrenal gland consisting of the zona glomerulosa, the zona fasciculata, and the zona reticularis. The adrenal cortex produces and secretes mineralocorticoids, glucocorticoids, and adrenal androgens. UBERON:0001235 adrenal cortex The thick outer layer of the adrenal gland that produces and secretes steroid hormones such as corticosterone, estrone and aldosterone. A C198975 UBERON Terminology C12397 Adrenal Medulla The inner region of the adrenal gland. The adrenal medulla produces, stores, and secretes epinephrine and norepinephrine. UBERON:0001236 adrenal medulla The inner portion of the adrenal gland that consists mainly of chromaffin cells which produce, store and secrete neurotransmitters such as epinephrine and norepinephrine. A C198975 UBERON Terminology C12375 Anal Canal The terminal section of the alimentary canal, which extends from the anorectal junction and ends at the anal opening. UBERON:0000159 anal canal The terminal part of the large intestine, continuous proximally with the rectum and distally terminates with the anus. A C198975 UBERON Terminology C32098 Anterior Mediastinum The area between the lungs; it contains the thymus, some lymph nodes, and vessels and branches of the internal thoracic artery. UBERON:0008820 anterior mediastinum The anterior mediastinum exists only on the left side where the left pleura diverges from the mid-sternal line. It is narrow, above, but widens out a little below. A C198975 UBERON Terminology C49477 Appendicular Skeleton The part of the skeleton that includes the bones of the upper and lower limbs. UBERON:0002091 appendicular skeleton Subdivision of skeleton which consists of all the skeletal elements in the pectoral and pelvic appendage complexes[cjm]. A C198975 UBERON Terminology C32144 Articular Cartilage The cartilage that covers the ends of each bone in a joint. UBERON:0010996 articular cartilage of joint A thin layer of cartilage, usually hyaline, on the articular surface of bones in synovial joints. A C198975 UBERON Terminology C12904 Axillary Lymph Node One of approximately 20-30 lymph nodes in chain formation that traverse the concavity of the underarm to the clavicle. UBERON:0001097 axillary lymph node The lymph nodes located around the axillary vein that receive lymphatic drainage from the upper or forelimb, scapular region and pectoral region. A C198975 UBERON Terminology C12305 Axillary Tail of the Breast The superolateral extension of the mammary gland into the axilla that consists of fibroadipose tissue, lymph nodes, and lymphatics. UBERON:0035289 axillary tail of breast An extension of the tissue of the breast which extends into the axilla. A C198975 UBERON Terminology C12270 Body of the Pancreas The part of the pancreas from the point where it crosses the portal vein to the point where it enters the lienorenal ligament. UBERON:0001150 body of pancreas The body of the pancreas is a subsection of the pancreas organ in the human body. It is somewhat prismatic in shape, and has three surfaces: anterior, posterior, and inferior. It is at the same level as the transpyloric plane. [WP,unvetted]. A C198975 UBERON Terminology C12258 Body of Stomach The main section of the digestive tube that connects the esophagus to the small intestine. The body proper excludes the upper and lower sections of the fundus and pyloric portion respectively. UBERON:0001161 body of stomach The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined[GO]. A C198975 UBERON Terminology C12316 Corpus Uteri The Corpus uteri, or body of uterus, is the part of the uterus above the isthmus, comprising about two thirds of the non-pregnant organ. UBERON:0009853 body of uterus The part of the uterus above the isthmus and below the orifices of the uterine tubes. A C198975 UBERON Terminology C12366 Bone The structural organ comprised of specialized connective tissue that forms the skeletal components of the body. UBERON:0001474 || UBERON:0002481 bone element Skeletal element that is composed of bone tissue. A C198975 UBERON Terminology C12356 Brain Ventricle The four connected cavities (hollow spaces) centrally located within the brain that connect posteriorly with the central canal of the spinal cord. UBERON:0004086 brain ventricle One of the system of communicating cavities in the brain that are continuous with the central canal of the spinal cord, that like it are derived from the medullary canal of the embryo, that are lined with an epithelial ependyma, and that contain a serous fluid. A C198975 UBERON Terminology C12689 Cauda Equina The collection of spinal nerve roots, arising from lumbar pairs two through five, sacral pairs one through five, and the coccygeal nerve, that branch off the conus medullaris at the termination of the spinal cord, and float freely within the lumbar cistern before exiting the spinal column at the appropriate vertebra. UBERON:0012337 cauda equina The cauda equina is a structure within the lower end of the spinal column of most vertebrates, that consists of nerve roots and rootlets from above. The space in which the cerebrospinal fluid is present is actually an extension of the subarachnoid space. A C198975 UBERON Terminology C12891 Central Canal of Spinal Cord The hollow tube filled with cerebrospinal fluid that begins in the inferior portion of the fourth ventricle and runs the entire length of the spinal. UBERON:0002291 central canal of spinal cord Spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord. A C198975 UBERON Terminology C32726 Hemisphere of the Cerebellum Either side of the cerebellum separated by the vermis. UBERON:0002245 cerebellar hemisphere A paired regions of the cerebellum that lie outside and lateral to the central vermis[MP]. The cerebellum consists of three parts, a median and two lateral, which are continuous with each other, and are substantially the same in structure. The median portion is constricted, and is called the vermis, from its annulated appearance which it owes to the transverse ridges and furrows upon it; the lateral expanded portions are named the hemispheres. The lateral hemisphere is considered the portion of the cerebellum to develop most recently. [WP,unvetted]. A C198975 UBERON Terminology C32298 Cervical Lymph Node Any of the lymph nodes located in the neck. UBERON:0002429 cervical lymph node Cervical lymph nodes are lymph nodes found in the neck. [WP,unvetted]. A C198975 UBERON Terminology C69313 Cervical Spine The set of vertebrae immediately caudal to the skull. UBERON:0006072 cervical region of vertebral column That portion of the spine comprising the cervical vertebrae. The neck area of the spine. A C198975 UBERON Terminology C12892 Cervical Spinal Cord The portion of the spinal cord located in the cervical region. UBERON:0002726 cervical spinal cord A spinal cord segment that adjacent_to a cervical region. A C198975 UBERON Terminology C13070 Cheek The fleshy part of the face bounded by the eyes, nose, ear, and jaw line. UBERON:0001567 cheek A fleshy subdivision of one side of the face bounded by an eye, ear and the nose. A C198975 UBERON Terminology C12345 Ciliary Body Tissue located behind the iris and composed of muscle and epithelium. Its functions include the production of aqueous humor and changing the shape of the crystalline lens. UBERON:0001775 ciliary body The thickened portion of the vascular tunic, which lies between the choroid and the iris, composed of ciliary muscle and ciliary processes. A C198975 UBERON Terminology C12447 Basal Ganglia Clusters of neurons comprising the globus pallidus, putamen, caudate, nucleus accumbens, substantia nigra and subthalamic nucleus. They are involved with high level aspects of inhibitory motor activity in coordination with the excitation commands issued from the cerebellum. UBERON:0010011 collection of basal ganglia Subcortical masses of gray matter in the forebrain and midbrain that are richly interconnected and so viewed as a functional system. The nuclei usually included are the caudate nucleus (caudoputamen in rodents), putamen, globus pallidus, substantia nigra (pars compacta and pars reticulata) and the subthalamic nucleus. Some also include the nucleus accumbens and ventral pallidum. A C198975 UBERON Terminology C12418 Head and Neck For oncology, an area of the body generally construed to comprise the base of skull and facial bones, sinuses, orbits, salivary glands, oral cavity, oropharynx, larynx, thyroid, facial and neck musculature and lymph nodes draining these areas. UBERON:0007811 craniocervical region The anteriormost subdivision of the body that includes the head, jaws, pharyngeal region and the neck (if present). In vertebrates this is the subdivision that includes the cervical vertebrae. A C198975 UBERON Terminology C32431 Deep Cervical Lymph Node Lymph nodes located deep to the sternocleidomastoid muscle, which surround the internal jugular vein, and serve as the main pathway of lymphatic drainage for the head and neck. UBERON:0004722 deep cervical lymph node The deep cervical lymph nodes are a group of cervical lymph nodes found near the internal jugular vein. They can be divided into upper and lower groups, or superior and inferior groups. Alternatively, they can be divided into deep anterior cervical lymph nodes and deep lateral cervical lymph nodes. They can also be divided into three groups: superior deep jugular, middle deep jugular, and inferior deep jugular. A C198975 UBERON Terminology C12459 Thalamus An ovoid mass composed predominantly of gray substance and associated laminae of white substance. The thalamus is divided into anterior, medial, and lateral parts. The function of the thalamus is to relay sensory impulses and cerebellar and basal ganglia projections to the cerebral cortex. The thalamus is positioned within the posterior part of the diencephalon forming most of each lateral wall of the third ventricle. UBERON:0010225 || UBERON:0001897 dorsal plus ventral thalamus Subcortical brain region consisting of paired gray matter bodies in the dorsal diencephalon and forming part of the lateral wall of the third ventricle of the brain. The thalamus represents the major portion of the diencephalon and is commonly divided into cellular aggregates known as nuclear groups.(MeSH). The dorsal topographic division of the interbrain. The macrodissected adult human thalamus was clearly illustrated by Vesalius in 1543 and the term as defined here was introduced by His in 1893. It includes the traditional epithalamus, dorsal thalamus, and ventral thalamus of Herrick (1910, pp. 494, 498). Also see Kuhlenbeck (1927, Ch. 9) and Jones (1985, p. 87). A C198975 UBERON Terminology C12310 Ectocervix The portion of the cervix that extends into the vaginal vault, and is lined with stratified squamous epithelium. UBERON:0012249 ectocervix The part of the cervix uteri that protrudes into the vagina and is lined with stratified squamous epithelium. A C198975 UBERON Terminology C12309 Endocervix The portion of the cervix which is lined by single columnar epithelium (mucosa). UBERON:0000458 endocervix The region of the opening of the uterine cervix into the uterine cavity. A C198975 UBERON Terminology C12705 Endocrine System The body system that comprises the organs and glands that produce hormones that are secreted into the blood and control physiological functions that include reproduction, growth and development, metabolism, and stress responses. UBERON:0000949 endocrine system Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity. A C198975 UBERON Terminology C12313 Endometrium The mucous membrane comprising the inner layer of the uterine wall; it consists of a simple columnar epithelium and a lamina propria that contains simple tubular uterine glands. The structure, thickness, and state of the endometrium undergo marked change with the menstrual cycle. UBERON:0001295 endometrium The glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy. A C198975 UBERON Terminology C32573 Extrahepatic Bile Duct The portion of the biliary tract outside the liver; the common hepatic duct joins the cystic duct to form the common bile duct. UBERON:0003703 extrahepatic bile duct Passages external to the liver for the conveyance of bile. These include the common bile duct and the common hepatic duct. A C198975 UBERON Terminology C32575 Eyebrow The arched strip of hair on the bony ridge above each eye socket. UBERON:0010163 eyebrow The eyebrow is an area of thick, delicate hairs above the eye that follows the shape of the lower margin of the brow ridges. Their main function is to protect the eye, but they are also important to human communication and facial expression. It is not uncommon for people to modify their eyebrows by means of hair addition or removal, make up, or piercings. A C198975 UBERON Terminology C12713 Eyelid A thin membrane of skin with the purpose of covering and protecting an eye. UBERON:0001711 eyelid A fold of skin that covers and protects part of the eyeball. Examples: upper eyelid, lower eyelid, nictitating membrane. A C198975 UBERON Terminology C12402 Female Reproductive System The collection of organs and tissues, including the ovaries, genital tract, and breasts, that have several functions, including sexual maturation, pregnancy, and childbirth. UBERON:0000474 female reproductive system The organs and associated structures associated with bearing offspring in a female animal. A C198975 UBERON Terminology C164048 Skin of the Upper Extremity The integumentary covering of the upper extremities. UBERON:0003531 forelimb skin A zone of skin that is part of a forelimb [Automatically generated definition]. A C198975 UBERON Terminology C48939 Bladder Fundus The portion of the bladder that is formed by the posterior wall and is located opposite to the bladder opening. UBERON:0006082 fundus of urinary bladder The base or posterior surface of the urinary bladder contains the trigone of the bladder and the outlet where urine empties through the internal urethral orifice. A C198975 UBERON Terminology C12810 Genitourinary System The body system that includes all organs involved in reproduction and in the formation and voidance of urine. UBERON:0004122 genitourinary system Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction. A C198975 UBERON Terminology C54204 Lower Gingiva The gingiva covering the mandibular alveolar bone. UBERON:0011602 gingiva of lower jaw A gingiva that is part of a lower jaw region. A C198975 UBERON Terminology C54205 Upper Gingiva The gingiva covering the maxillary alveolar bone. UBERON:0011601 gingiva of upper jaw A gingiva that is part of a upper jaw region. A C198975 UBERON Terminology C12419 Head The anterior and superior part of a human bearing the mouth, the brain and sensory organs. UBERON:0000033 head The head is the anterior-most division of the body [GO]. A C198975 UBERON Terminology C12269 Head of the Pancreas That portion of the pancreas lying in the concavity of the duodenum. UBERON:0001069 head of pancreas The head of pancreas is a portion of the pancreas that is lodged within the curve of the duodenum, and is flattened anteriorly (from before). The other parts of the pancreas are the body and the tail. Its upper border is overlapped by the superior part of the duodenum and its lower overlaps the horizontal part; its right and left borders overlap in front, and insinuate themselves behind, the descending and ascending parts of the duodenum respectively. [WP,unvetted]. A C198975 UBERON Terminology C12909 Hematopoietic System The bodily system of organs and tissues, primarily the bone marrow, spleen, tonsils, and lymph nodes, involved in the production of blood. UBERON:0002390 hematopoietic system Anatomical system that is involved in the production of hematopoietic cells. A C198975 UBERON Terminology C164047 Skin of the Lower Extremity The integumentary covering of the lower extremities. UBERON:0003532 hindlimb skin A zone of skin that is part of a hindlimb [Automatically generated definition]. A C198975 UBERON Terminology C33645 Subcutis Adipose tissue located under the dermis. It binds underlying structures with the skin. The subcutis is important in the regulation of temperature of the skin itself and the body. The size of this layer varies throughout the body and from person to person. UBERON:0002072 hypodermis Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. A C198975 UBERON Terminology C12458 Hypothalamus A small, cone shaped collection of nuclei in the brain that is located below the thalamus and forms the lower side wall and floor of the third ventricle. It regulates homeostasis, the sleep-wake cycle, and metabolism, and plays a role in autonomic, endocrine, and motor function control. UBERON:0001898 hypothalamus A specialized brain region of the ventral diencephalon arising near the end of the segmentation period; the embryonic hypothalamic region will give rise to the posterior pituitary gland as well as a number of brain nuclei. [ZFA]. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland (hypophysis).[Wikipedia]. A C198975 UBERON Terminology C32801 Inguinal Lymph Node A superficial or deep lymph node located in the inguinal area. UBERON:0001542 inguinal lymph node The lymph nodes located in the groin area. A C198975 UBERON Terminology C95443 Internal Auditory Canal A canal in the petrous region of the temporal bone that serves as the passage for cranial nerves (mainly the VII and VIII cranial nerves) towards the middle and inner ear. UBERON:0011859 internal acoustic meatus The internal auditory meatus (also internal acoustic meatus, internal auditory canal, and internal acoustic canal) is a canal in the petrous bone of the temporal bone of the skull that carries nerves from inside the cranium towards the middle and inner ear compartments namely cranial nerve VII and cranial nerve VIII. A C198975 UBERON Terminology C12736 Intestine The portion of the gastrointestinal tract between the stomach and the anus. It includes the small intestine and large intestine. UBERON:0000160 intestine Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine. A C198975 UBERON Terminology C12677 Intrahepatic Bile Duct The bile ducts which are located within the liver. They include the small interlobular bile ducts, intrahepatic large bile ducts, and the intrahepatic portions of the left and right hepatic ducts. UBERON:0003704 intrahepatic bile duct Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct. A C198975 UBERON Terminology C12261 Lesser Curvature of the Stomach The right border of the stomach. It is concave in shape and extends from the cardiac orifice to the pyloric orifice. UBERON:0001163 lesser curvature of stomach The lesser curvature of the stomach, extending between the cardiac and pyloric orifices, forms the right or posterior border of the stomach. It descends as a continuation of the right margin of the esophagus in front of the fibers of the right crus of the diaphragm, and then, turning to the right, it crosses the first lumbar vertebra and ends at the pylorus. Nearer its pyloric than its cardiac end is a well-marked notch, the incisura angularis, which varies somewhat in position with the state of distension of the viscus; it serves to separate the stomach into a right and a left portion. The lesser curvature gives attachment to the two layers of the hepatogastric ligament, and between these two layers are the left gastric artery and the right gastric branch of the hepatic artery. [WP,unvetted]. A C198975 UBERON Terminology C12302 Lower-Inner Quadrant of the Breast The quarter of the breast which is inferior and medial. UBERON:0035477 lower inner quadrant of breast The quarter of the breast which is inferior and medial. A C198975 UBERON Terminology C33020 Lower Lobe of the Left Lung The larger lobe of the left lung, situated below and behind the oblique fissure. UBERON:0008953 lower lobe of left lung A lower lobe of lung that is part of a left lung. A C198975 UBERON Terminology C12287 Lower Lobe of the Lung The bottom most subdivision of either the right or left lung. UBERON:0008949 lower lobe of lung The bottom most subdivision of either the right or left lung. A C198975 UBERON Terminology C12304 Lower-Outer Quadrant of the Breast The quarter of the breast which is inferior and lateral. UBERON:0035365 lower outer quadrant of breast The quarter of the breast which is inferior and lateral. A C198975 UBERON Terminology C69314 Lumbar Spine Those vertebrae between the ribs and the pelvis, L1-L5 in man. UBERON:0006074 lumbar region of vertebral column Subdivision of vertebral column that corresponds to the lumbar subdivision of the body, containing the lumbar vertebrae. A C198975 UBERON Terminology C12284 Main Bronchus One of two major branches of the trachea. Bifurcation of the trachea at the carina forms the left main bronchus and the right main bronchus. UBERON:0002182 main bronchus One of two branches of the trachea. A C198975 UBERON Terminology C12999 Major Salivary Gland One of the three larger salivary glands including the parotid, submandibular and sublingual glands. UBERON:0001829 major salivary gland One of the three largest glands of the oral cavity that secrete most of the saliva, including the parotid, submandibular, and sublingual glands. A C198975 UBERON Terminology C12367 Mammary Gland In humans, the glands of the breast, consisting of fibrous tissue connecting the lobes and fatty tissue in between the lobes. UBERON:0001911 mammary gland A specialized accessory gland of the skin of mammals that secretes milk. The gland is typically only developed in females, and regresses in males. A C198975 UBERON Terminology C12442 Medulla Oblongata The lower portion of the brainstem located between the pons and the spinal cord. This structure contains several descending and ascending tracts, lower cranial nerve nuclei, a significant proportion of the reticular system of the brainstem and other structures. UBERON:0001896 medulla oblongata Organ component of neuraxis that has as its parts the medullary reticular formation, inferior olivary complex and cochlear nuclear complex, among other structures[FMA]. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate[GO]. A C198975 UBERON Terminology C12348 Meninges Any one of three membranes that surround the brain and spinal cord. UBERON:0010743 meningeal cluster The collection of all meningeal layers that line a central nervous system. A C198975 UBERON Terminology C12350 Spinal Meninges Connective tissue membranes that surround and support the spinal cord and cauda equina. They are continuous with cerebral meninges, which surround and support the brain. UBERON:0003292 meninx of spinal cord A meninx that is part of a spinal cord [Automatically generated definition]. A C198975 UBERON Terminology C12510 Mesencephalon The uppermost portion of the brainstem located between the pons and the diencephalon. The midbrain contains the cerebral peduncles, oculomotor, trochlear and red nuclei, substantia nigra and various other nuclei and tracts. UBERON:0001891 midbrain The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]. A C198975 UBERON Terminology C12274 Middle Ear The part of the ear including the eardrum and ossicles. The middle ear leads to the inner ear. UBERON:0001756 middle ear The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window)[GO]. A C198975 UBERON Terminology C32205 Bladder Mucosa The mucous membrane that is the inner lining of the urinary bladder. UBERON:0001259 mucosa of urinary bladder The mucous membrane lining the urinary bladder. A C198975 UBERON Terminology C12314 Myometrium The smooth muscle lining the uterus. UBERON:0001296 myometrium The smooth muscle coat of the uterus, which forms the main mass of the organ and surrounds and supports the endometrium. A C198975 UBERON Terminology C12336 Bladder Neck The inferior portion of the urinary bladder which is formed as the walls of the bladder converge and become contiguous with the proximal urethra. UBERON:0001258 neck of urinary bladder The constricted portion of the urinary bladder, formed by the meeting of its inferolateral surfaces proximal to the opening of the urethra[MP]. A C198975 UBERON Terminology C12755 Nervous System The entire nerve apparatus, composed of a central part, the brain and spinal cord, and a peripheral part, the cranial and spinal nerves, autonomic ganglia, and plexuses. UBERON:0001016 nervous system The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. A C198975 UBERON Terminology C12299 Nipple The pigmented protuberance on the surface of the breast through which milk is drawn from the breast. UBERON:0002030 nipple Projection of skin containing the outlets for 15-20 lactiferous ducts arranged cylindrically around the tip. A C198975 UBERON Terminology C12355 Occipital Lobe One of the four regions of cortex in each cerebral hemisphere. It is located posterior to the temporal lobe and inferior to the parietal lobe. UBERON:0002021 occipital lobe Posterior part of the cerebral hemisphere (MSH). A C198975 UBERON Terminology C32574 Eye Appendage Any accessory organ of the eye, including the eyelids, eyebrows, lacrimal apparatus, or conjunctiva. UBERON:0035639 ocular adnexa The parts of the orbital region that are outside of the the eyeball, including the lacrimal apparatus, the extraocular muscles and the eyelids, eyelashes, eyebrows and the conjunctiva. A C198975 UBERON Terminology C12344 Choroid A blood vessel-containing membrane of the eye that lies between the retina and the sclera. UBERON:0001776 optic choroid Vascular layer containing connective tissue, of the eye lying between the retina and the sclera. The choroid provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, the choroid forms the uveal tract[WP]. A C198975 UBERON Terminology C33218 Optic Tract A continuation of the optic nerves just dorsal to the optic chiasm, formed by temporal fibers of the ipsilateral optic nerve and nasal fibers of the contralateral optic nerve, that carries axons to nuclei within the thalamus and relays visual information to the primary visual cortex of the occipital lobe. UBERON:0001908 optic tract Diencephalic white matter (tract) which is comprised of retinal ganglion cell axons after which they have passed through the optic chiasm[ZFA]. Predominantly white matter structure found in diencephalon consisting of fibers originating in the retina. The optic tract is considered to extend from the point of the optic chiasm and terminates largely, although not exclusively, in the lateral geniculate complex. Other fibers end in the superior colliculus and other structures in the diencephalon, midbrain and brainstem (MM)[NIF]. A C198975 UBERON Terminology C207628 Para-aortic Body Small masses of chromaffin cells that are located alongside the abdominal aorta from above the level of the superior mesenteric artery to below the level of the aortic bifurcation. Derived from neural crest, para-aortic bodies are the main source of fetal catecholamines and normally regress after birth. UBERON:0001237 paraaortic body A chromaffin paraganglion located at the bifurcation of the aorta or at the origin of the inferior mesenteric artery. A C198975 UBERON Terminology C12354 Parietal Lobe One of the lobes of the cerebral hemisphere located superiorly to the occipital lobe and posteriorly to the frontal lobe. Cognition and visuospatial processing are its main functions. UBERON:0001872 parietal lobe Upper central part of the cerebral hemisphere. (MSH). A C198975 UBERON Terminology C12465 Peripheral Nervous System That part of the nervous system consisting of the nerves and neurons that reside or extend outside the central nervous system. UBERON:0000010 peripheral nervous system A major division of the nervous system that contains nerves which connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. A C198975 UBERON Terminology C12840 Pleural Cavity The potential space between parietal and visceral pleurae. There is a separate pleural cavity for each lung. UBERON:0002402 pleural cavity The fluid-filled cavity that lies between the visceral and parietal pleurae. A C198975 UBERON Terminology C12511 Pons Varolii The middle portion of the brainstem located between the midbrain and the medulla oblongata. The fourth ventricle lies dorsal to the pons which also contains the motor trigeminal nuclei and the abducens nuclei. The cerebellum contributes a large number of afferent fibers to the pons. UBERON:0000988 pons The part of the central nervous system lying between the medulla oblongata and the midbrain, ventral to the cerebellum. A C198975 UBERON Terminology C33361 Posterior Cranial Fossa The infratentorial compartment of the cranial cavity. Its boundaries are formed by the sphenoid bone, temporal bone, and parietal bone, and it contains the cerebellum and brain stem. UBERON:0008788 posterior cranial fossa The infratentorial compartment that contains the CEREBELLUM and BRAIN STEM. It is formed by the posterior third of the superior surface of the body of the sphenoid (SPHENOID BONE), by the occipital, the petrous, and mastoid portions of the TEMPORAL BONE, and the posterior inferior angle of the PARIETAL BONE. A C198975 UBERON Terminology C33368 Posterior Mediastinum The part of the lower portion of the mediastinum that is located behind the pericardium. UBERON:0008822 posterior mediastinum The posterior mediastinum is an irregular triangular space running parallel with the vertebral column. A C198975 UBERON Terminology C12228 Base of Tongue The posterior one third of the tongue behind the terminal sulcus that forms the anterior aspect of the oropharynx responsible for swallowing and modification of the voice in speech. UBERON:0010033 posterior part of tongue The Posterior tongue, or pharyngeal part, is the part of the tongue behind the terminal sulcus. At its root, it is directed backward, and connected with the hyoid bone by the Hyoglossi and Genioglossi muscles and the hyoglossal membrane; with the epiglottis by three folds (glossoepiglottic) of mucous membrane; with the soft palate by the glossopalatine arches; and with the pharynx by the Constrictores pharyngis superiores and the mucous membrane. It is derived primarily from the third pharyngeal arch. (The second arch has a substantial contribution during fetal development, but this later atrophies. The fourth arch may also contribute, depending upon how the boundaries of the tongue are defined.). A C198975 UBERON Terminology C12259 Antrum Pylori The initial part of the pyloric canal of the stomach. This site contains endocrine cells that produce gastrin and somatostatin. UBERON:0001165 pyloric antrum The area at the bottom of the stomach on the caudal side of the pyloric canal that contains gastrin-producing G cells, which stimulate acid production, and the luminal pH-sensitive population of somatostatin-producing D cells. A C198975 UBERON Terminology C12777 Radius Bone The long bone of the forearm that extends from the lateral aspect of the elbow to the thumb-side of the wrist. UBERON:0001423 radius bone The major preaxial endochondral bone in the anterior zeugopod[Phenoscape]. A C198975 UBERON Terminology C12887 Renal Pelvis The funnel-shaped proximal portion of the ureter located within the kidney into which urine is secreted from the collecting duct system of the kidney. UBERON:0001224 renal pelvis A funnel shaped proximal portion of the ureter that is formed by convergence of the major calices [MP]. A C198975 UBERON Terminology C12413 Urinary System The organs involved in the creation and excretion of urine. UBERON:0001008 renal system The renal system in an anatomical system that maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. A C198975 UBERON Terminology C12779 Respiratory System The organs involved in the exchange of carbon dioxide and oxygen including the trachea, bronchi, and lung parenchyma. UBERON:0001004 respiratory system Functional system which consists of structures involved in respiration. A C198975 UBERON Terminology C12780 Reticuloendothelial System A network of phagocytic cells, primarily monocytes and macrophages, located in the connective tissue of the bone marrow, spleen, and liver that are involved in the clearance of bacteria, toxins, exogenous antigens, and immune complexes from the blood and tissues, as well as cytotoxicity against tumor cells. UBERON:0000363 reticuloendothelial system A part of the immune system that consists of the phagocytic cells located in reticular connective tissue. The cells are primarily monocytes and macrophages, and they accumulate in lymph nodes and the spleen. The Kupffer cells of the liver and tissue histiocytes are also part of the RES[WP]. A C198975 UBERON Terminology C54223 Retromolar Trigone A triangular-shaped area of mucosa located posterior the last mandibular molar tooth. UBERON:0012376 retromolar triangle The small area behind the wisdom teeth. A C198975 UBERON Terminology C12426 Salivary Gland An exocrine gland that secretes saliva. Salivary glands are mostly located in and around the oral cavity. UBERON:0001044 saliva-secreting gland Saliva-secreting exocrine glands of the oral cavity[GO]. A C198975 UBERON Terminology C12497 Sella Turcica A bony prominence situated on the upper surface of the body of the sphenoid bone housing the pituitary gland. UBERON:0003689 sella turcica The sella turcica is a saddle-shaped depression in the sphenoid bone at the base of the human skull. [WP,unvetted]. A C198975 UBERON Terminology C33561 Skin of the Face The integumentary covering of the face. UBERON:1000021 skin of face A zone of skin that is part of the face. A C198975 UBERON Terminology C52756 Neck Skin The integumentary covering of the neck. UBERON:0001417 skin of neck A zone of skin that is part of a neck [Automatically generated definition]. A C198975 UBERON Terminology C12295 Skin of the Trunk The skin or integument surrounding the trunk of the body. UBERON:0001085 skin of trunk A zone of skin that is part of a trunk [Automatically generated definition]. A C198975 UBERON Terminology C12231 Soft Palate The muscular extension of the hard palate which comprises the posterior of the oral cavity and the floor of the nasal cavity. UBERON:0001733 soft palate The muscular, non-bony arch-shaped posterior portion of the palate extending from the posterior edge of the hard palate. A C198975 UBERON Terminology C12329 Spermatic Cord A tube-like structure composed of the vas deferens and surrounding tissue layers, that runs from the abdomen to each of the testicles. UBERON:0005352 spermatic cord The cord-like structure in males comprising the vas deferens and associated tissue that runs from the abdomen down to each testis[MP]. A C198975 UBERON Terminology C12271 Tail of the Pancreas The left extremity of the pancreas within the lienorenal ligament. UBERON:0001151 tail of pancreas The tail of the pancreas, located anatomically left near the hilum of the spleen, is not simply an anatomical distinction. The tail is the only part of the pancreas which contains Pancreatic Polypeptide (PP) cells, which are responsible for secreting pancreatic polypeptide to coordinate exocrine and islet enzyme release. PP cells are found in the tail's periphery. Beta cells and delta cells are found in the central part of the tail as with the rest of the pancreas. The cells described above are located exclusively in the islet cells; their secretions reach exocrine portions of the pancreas via the capillary network surrounding the islet cell populations. [WP,unvetted]. A C198975 UBERON Terminology C12353 Temporal Lobe One of the cerebral lobes. It is located inferior to the frontal and parietal lobes and anterior to the occipital lobe. UBERON:0001871 temporal lobe Lower lateral part of the cerebral hemisphere. (MSH). A C198975 UBERON Terminology C12251 Thoracic Esophagus Clinical esophageal segment composed of smooth muscle. It includes the middle third topographic segment, as well as parts of the upper and lower thirds. UBERON:0035216 thoracic part of esophagus Zone of esophagus located in the thorax. A C198975 UBERON Terminology C12894 Thoracic Spinal Cord The portion of the spinal cord located in the thoracic region. UBERON:0003038 thoracic spinal cord The thoracic nerves are the spinal nerves emerging from the thoracic vertebrae. [WP,unvetted]. A C198975 UBERON Terminology C12331 Bladder Trigone The triangular area in the bladder mucosa that is formed by the two ureteral orifices and the urethral orifice. UBERON:0001257 trigone of urinary bladder The smooth triangular region of the wall of the urinary bladder formed by the two ureteral orifices and the internal urethral orifice; it is an area in which the muscle fibers are closely adherent to the mucosa. A C198975 UBERON Terminology C12301 Upper-Inner Quadrant of the Breast The quarter of the breast which is superior and medial. UBERON:0035542 upper inner quadrant of breast The quarter of the breast which is superior and medial. A C198975 UBERON Terminology C12285 Upper Lobe of the Lung The upper-most lobe of either lung. UBERON:0008948 upper lobe of lung A lobe of the lung that is closest to the head. A C198975 UBERON Terminology C12303 Upper-Outer Quadrant of the Breast The quarter of the breast which is superior and lateral. UBERON:0035328 upper outer quadrant of breast The quarter of the breast which is superior and lateral. A C198975 UBERON Terminology C12338 Urachus A cord of fibrous tissue that extends from the urinary bladder to the umbilicus. The urachus is a remnant of the fetal urinary canal. UBERON:0002068 urachus A fibrous remnant of the allantoic stalk, a narrow fetal canal connecting the apex of the urinary bladder with the umbilicus located in the space of Retzius, between the transversalis fascia anteriorly and the peritoneum posteriorly. its lumen is normally obliterated during development, transforming the urachus into a solid cord, a functionless remnant that persists throughout life as the median umbilical ligament; failure of complete lumen obliteration may result in distinct congenital urachal remnant anomalies[MP]. A C198975 UBERON Terminology C12337 Ureteric Orifice The opening of the ureter in the bladder that is situated at the lateral angle of the trigone. UBERON:0012303 ureteral orifice The slit-like opening of either ureter into the bladder; normally, the two ureteral orifices are placed at the posterolateral angles of the urinary bladder trigone while the internal urethral orifice is placed at its anteroinferior angle (apex); wide gaping usually indicates vesicoureteral reflux. A C198975 UBERON Terminology C48941 Bladder Wall The tissue layers that form the urinary bladder. They include the mucosa, submucosa, smooth muscle, and serosa. UBERON:0001256 wall of urinary bladder An anatomical wall that lines the insider of a urinary bladder. A C198975 UBERON Terminology C12244 Lateral Wall of the Nasopharynx The aspect of the nasopharyngeal wall that is located on the side. It contains the pharyngeal opening of the auditory tube. UBERON:0035383 lateral wall of nasopharynx A C198975 UBERON Terminology C12895 Lumbar Spinal Cord The portion of the spinal cord located in the lumbar region. UBERON:0002792 lumbar spinal cord A C198975 UBERON Terminology C12240 Posterior Wall of the Oropharynx The dorsal portion of the oropharyngeal cavity that is formed by the muscular pharyngeal wall comprising the superior and middle pharyngeal constrictor muscles. UBERON:0035240 posterior wall of oropharynx C C198975 UBERON Terminology C34082 Gastrointestinal Tract The upper gastrointestinal (GI) tract is comprised of mouth, pharynx, esophagus and stomach while the lower GI tract consists of intestines and anus. The primary function of the GI tract is to ingest, digest, absorb and ultimately excrete food stuff. UBERON:0001555 || UBERON:0005409 alimentary part of gastrointestinal system || digestive tract digestive tube || enteric tract A tube extending from the mouth to the anus. || The part of the digestive system that excludes the hepatobiliary system. C C198975 UBERON Terminology C204859 Mammary Region The region of the torso containing the breasts and/or mammary glands. UBERON:0000310 breast mammary part of chest || mammary region The upper ventral region of the torso of an organism. C C198975 UBERON Terminology C89803 Forehead The part of the face between the eyebrows and the normal hairline. UBERON:0008200 forehead In human anatomy, the forehead is the fore part of the head. It is, formally, an area of the head bounded by three features, two of the skull and one of the scalp. The top of the forehead is marked by the hairline, the edge of the area where hair on the scalp grows. The bottom of the forehead is marked by the supraorbital ridge, the bone feature of the skull above the eyes. The two sides of the forehead are marked by the temporal ridge, a bone feature that links the supraorbital ridge to the coronal suture line and beyond. C C198975 UBERON Terminology C32677 Gingiva The soft tissue surrounding the neck of individual teeth as well as covering the alveolar bone. The tissue is fibrous and continuous with the periodontal ligament and mucosal covering. UBERON:0001828 gingiva gum || gum tissue || gums The fibrous investing tissue, covered by keratinized epithelium, that immediately surrounds a tooth and is contiguous with its periodontal ligament and with the mucosal tissues of the mouth. C C198975 UBERON Terminology C54187 Floor of Mouth The horseshoe-shaped part of the oral cavity bounded superiorly by the ventral surface of the tongue, inferiorly by the mylohyoid muscle, anterolaterally by the gingival surfaces of the mandible, and posteriorly by the anterior tonsillar pillar. UBERON:0003679 mouth floor floor of mouth || floor of oval cavity || floor of the oval cavity The ventral area of the mouth. In organisms with a tongue, this is the area under the ventral surface of the tongue. C C198975 UBERON Terminology C33282 Patella A small flat triangular bone in front of the knee that articulates with the femur and protects the knee joint. UBERON:0002446 patella A large sesamoid bone found in the distal femur/proximal tibial region of the hindlimb of tetrapods. The patella is the attachment site for proximal hindlimb tendons. C C198975 UBERON Terminology C12398 Pineal Gland A small endocrine gland in the brain, situated beneath the back part of the corpus callosum, that secretes melatonin. UBERON:0001905 pineal body corpus pineale || glandula pinealis || pineal gland A midline, cone like structure located in the dorso-caudal roof of the 3rd ventricle, attached by peduncles to the habenular and posterior commissures. The stalk contains nerve fibers, blood vessels, connective tissue and parenchymal cells (Paxinos, The Rat Central Nervous System, 2nd ed, pg 399).