NCIt Code	NCIt PT	Subset PT	Subset SY	NCIt Definition	Subset Definition	NCIt Code of First Parent	First Parent	NCIt Code of Second Parent	Second Parent	NCIt Code of Subset	PT of NICHD Subset	Subset Antiquated PT	Subset Antiquated SY
C	C34976	Tick-Borne Relapsing Fever	Tick-Borne Relapsing Fever		An infection that is caused by certain species of Rickettsia or Borrelia, which are transmitted to humans from infected ticks; it is characterized by sudden fever, chills, headaches, myalgia, arthralgia, nausea, and possibly a rash. Symptoms usually persist for two to nine days, then disappear, with recurrence after several weeks if the patient remains untreated.|Relapsing fever vectored by ticks, resulting from infection with Borrelia.	An infection that is caused by certain species of Rickettsia or Borrelia, which are transmitted to humans from infected ticks; it is characterized by sudden fever, chills, headaches, myalgia, arthralgia, nausea, and possibly a rash. Symptoms usually persist for two to nine days, then disappear, with recurrence after several weeks if the patient remains untreated.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C112019	Surgical Site Infection	Surgical Site Infection		An infection that occurs at a surgical site within 30 days after an operation.	An infection that occurs after surgery in the part of the body where surgery was performed.	C2959	Complication	C128320	Infection	C90259	Pediatric Terminology		
C	C117984	Pediatric Infectious Disorder	Pediatric Infectious Disease		An infectious disorder that occurs during infancy, childhood, or adolescence.	An infectious disease that occurs in infancy, childhood, or adolescence.	C26726	Infectious Disorder	C89328	Pediatric Disorder	C90259	Pediatric Terminology		
C	C128337	Yersiniosis	Yersiniosis		An infection that is caused by Yersinia enterocolitica or Yersinia pseudotuberculosis, and that is usually acquired by consumption of contaminated meat, water, or unpasteurized milk. It can also be transmitted vertically, pre- or perinatally, from mother to infant. Manifestation of symptoms depends on the infecting species and mode of acquisition, and can range from gastrointestinal syndromes to septicemia.	An infection that is caused by Yersinia enterocolitica or Yersinia pseudotuberculosis, and that is usually acquired by consumption of contaminated meat, water, or unpasteurized milk. It can also be transmitted vertically, pre- or perinatally, from mother to infant. Manifestation of symptoms depends on the infecting species and mode of acquisition, and can range from gastrointestinal syndromes to septicemia.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128340	Bacillary Peliosis	Bacillary Peliosis		An infection that is caused by Bartonella henselae, which occurs primarily in immunocompromised persons; it is characterized by blood-filled cysts in the liver and spleen.	An infection that is caused by Bartonella henselae, which occurs primarily in immunocompromised persons; it is characterized by blood-filled cysts in the liver and spleen.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128370	Fungal Keratitis	Fungal Keratitis		Keratitis caused by fungi.	Keratitis caused by fungi.	C3245	Fungal Infection	C26805	Keratitis	C90259	Pediatric Terminology		
C	C128375	Infectious Meningoencephalitis	Infectious Meningoencephalitis		Inflammation of the meninges and brain caused by an infectious agent.	Inflammation of the meninges and brain caused by an infectious agent.	C26726	Infectious Disorder	C34813	Meningoencephalitis	C90259	Pediatric Terminology		
C	C128380	Bacterial Myocarditis	Bacterial Myocarditis		Myocarditis that is caused by an infection with a bacterial agent.	Myocarditis that is caused by an infection with a bacterial agent.	C2890	Bacterial Infection	C34831	Myocarditis	C90259	Pediatric Terminology		
C	C128381	Viral Myocarditis	Viral Myocarditis		Myocarditis that is caused by an infection with a viral agent.	Myocarditis that is caused by an infection with a viral agent.	C34831	Myocarditis	C3439	Viral Infection	C90259	Pediatric Terminology		
C	C128382	Pyomyositis	Pyomyositis	Tropical Pyomyositis	A suppurative infection of muscle.	A suppurative infection of muscle.	C26726	Infectious Disorder	C110937	Musculoskeletal Finding	C90259	Pediatric Terminology		
C	C128387	Fasciolosis	Fasciolosis	Fascioliasis	A parasitic infection that is caused by liver flukes, usually Fasciola hepatica, of sheep, goats, and cattle. Humans become infected by eating uncooked, infested aquatic vegetation (classically watercress). Adult flukes inhabit the bile ducts, gallbladder, and occasionally ectopic sites. Symptoms arise secondary to inflammatory response or obstruction.	A parasitic infection that is caused by liver flukes, usually Fasciola hepatica, of sheep, goats, and cattle. Humans become infected by eating uncooked, infested aquatic vegetation (classically watercress). Adult flukes inhabit the bile ducts, gallbladder, and occasionally ectopic sites. Symptoms arise secondary to inflammatory response or obstruction.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128388	Fasciolopsiasis	Fasciolopsiasis		A small bowel infection that is caused by Fasciolopsis buski, which is endemic in the Far East and Southeast Asia, and which is transmitted via the consumption of raw or undercooked aquatic plants. The spectrum of manifestations range from  asymptomatic to intestinal symptoms from local invasion or allergic response.	A small bowel infection that is caused by Fasciolopsis buski, which is endemic in the Far East and Southeast Asia, and which is transmitted via the consumption of raw or undercooked aquatic plants. The spectrum of manifestations range from  asymptomatic to intestinal symptoms from local invasion or allergic response.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128389	Heterophyiasis	Heterophyiasis		An infection that is caused by the intestinal fluke Heterophyes heterophyes, which is most commonly found in Asia, the Middle East, and Africa, and which is transmitted via consumption of contaminated raw or undercooked fish. Symptoms typically range from asymptomatic to intermittent abdominal pain and diarrhea, with occasional ectopic infection.	An infection that is caused by the intestinal fluke Heterophyes heterophyes, which is most commonly found in Asia, the Middle East, and Africa, and which is transmitted via consumption of contaminated raw or undercooked fish. Symptoms typically range from asymptomatic to intermittent abdominal pain and diarrhea, with occasional ectopic infection.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128390	Metagonimiasis	Metagonimiasis		An infection that is most commonly caused by the intestinal fluke Metagonimus yokogawai, which is most commonly found in the Far East, and which is transmitted via consumption of contaminated raw or undercooked fish. Symptoms typically range from asymptomatic to intermittent abdominal pain and diarrhea, with occasional ectopic infection.	An infection that is most commonly caused by the intestinal fluke Metagonimus yokogawai, which is most commonly found in the Far East, and which is transmitted via consumption of contaminated raw or undercooked fish. Symptoms typically range from asymptomatic to intermittent abdominal pain and diarrhea, with occasional ectopic infection.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128391	Diphyllobothriasis	Diphyllobothriasis		An infection that is caused by the tapeworm Diphyllobothrium latum and related species; it is transmitted via consumption of raw or undercooked fish, and symptoms include abdominal discomfort, diarrhea, vomiting, fatigue, weight loss, and vitamin B12 deficiency.	An infection that is caused by the tapeworm Diphyllobothrium latum and related species; it is transmitted via consumption of raw or undercooked fish, and symptoms include abdominal discomfort, diarrhea, vomiting, fatigue, weight loss, and vitamin B12 deficiency.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128392	Ascariasis	Ascariasis		An infection that is caused by the roundworm Ascaris lumbricoides, many cases of which remain asymptomatic. During the transient larval migratory phase, shortness of breath, fever, and eosinophilia can occur. Depending on the intestinal worm burden, a spectrum of gastrointestinal tract symptoms can occur.	An infection that is caused by the roundworm Ascaris lumbricoides, many cases of which remain asymptomatic. During the transient larval migratory phase, shortness of breath, fever, and eosinophilia can occur. Depending on the intestinal worm burden, a spectrum of gastrointestinal tract symptoms can occur.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128393	Anisakiasis	Anisakiasis		An infection that is caused by nematodes of the genus Anisakis, which is most commonly transmitted via ingestion of infective larvae from consumption of raw or undercooked fish or squid; it is characterized by invasion of the stomach wall or intestines, resulting in the death of the worm, and triggering an inflammatory response that surrounds the worm and that can result in intestinal obstruction.	An infection that is caused by nematodes of the genus Anisakis, which is most commonly transmitted via ingestion of infective larvae from consumption of raw or undercooked fish or squid; it is characterized by invasion of the stomach wall or intestines, resulting in the death of the worm, and triggering an inflammatory response that surrounds the worm and that can result in intestinal obstruction.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128394	Angiostrongyliasis	Angiostrongyliasis		An infection that is caused by nematodes of the genus Angiostrongylus; signs and symptoms are dependent on the invading species, but generally include gastrointestinal symptoms and fever, and can have extraintestinal manifestations (e.g., central nervous system, anterior and posterior eye).	An infection that is caused by nematodes of the genus Angiostrongylus; signs and symptoms are dependent on the invading species, but generally include gastrointestinal symptoms and fever, and can have extraintestinal manifestations (e.g., central nervous system, anterior and posterior eye).	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128395	Gnathostomiasis	Gnathostomiasis		An infection that is caused by nematodes of the genus Gnathostoma, which is commonly found in Southeast Asia, and which is transmitted via the consumption of contaminated raw/undercooked birds, eels, fish, frogs, or reptiles. The pattern of symptoms is species-dependent, and extraintestinal manifestations are due to larval migration (e.g., pulmonary infiltrates, eosinophilic meningitis, or painful, pruritic subcutaneous swellings, and peripheral blood eosinophilia).	An infection that is caused by nematodes of the genus Gnathostoma, which is commonly found in Southeast Asia, and which is transmitted via the consumption of contaminated raw/undercooked birds, eels, fish, frogs, or reptiles. The pattern of symptoms is species-dependent, and extraintestinal manifestations are due to larval migration (e.g., pulmonary infiltrates, eosinophilic meningitis, or painful, pruritic subcutaneous swellings, and peripheral blood eosinophilia).	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128397	Baylisascariasis	Baylisascariasis	Raccoon Roundworm Infection	An infection that is caused by the raccoon nematode Baylisascaris procyonis, which is transmitted by the ingestion of embryonated eggs in contaminated soil; symptoms depend on larval migration sites (visceral organs, eye, or brain) provoking severe inflammatory responses.	An infection that is caused by the raccoon nematode Baylisascaris procyonis, which is transmitted by the ingestion of embryonated eggs in contaminated soil; symptoms depend on larval migration sites (visceral organs, eye, or brain) provoking severe inflammatory responses.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128399	Trichuriasis	Trichuriasis	Whipworm Infection	An infection that is caused by the nematode Trichuris trichiura, a soil-transmitted helminth, which is transmitted via food and/or water contaminated with the eggs of the worm. Symptoms are usually mild and include abdominal pain, diarrhea, fatigue, and possibly anemia secondary to blood loss in diarrhea.	An infection that is caused by the nematode Trichuris trichiura, a soil-transmitted helminth, which is transmitted via food and/or water contaminated with the eggs of the worm. Symptoms are usually mild and include abdominal pain, diarrhea, fatigue, and possibly anemia secondary to blood loss in diarrhea.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128400	Myiasis	Myiasis		The infection of a fly larva (maggot) in human tissue, which most commonly occurs in tropical climates. Affected tissues most commonly include skin, especially if open wounds are present, nasal passages, ears, and eyes.	The infection of a fly larva (maggot) in human tissue, which most commonly occurs in tropical climates. Affected tissues most commonly include skin, especially if open wounds are present, nasal passages, ears, and eyes.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128404	Bacterial Pericarditis	Bacterial Pericarditis		Pericarditis that is caused by an infection with a bacterial agent.	Pericarditis that is caused by an infection with a bacterial agent.	C2890	Bacterial Infection	C34915	Pericarditis	C90259	Pediatric Terminology		
C	C128405	Viral Pericarditis	Viral Pericarditis		Pericarditis that is caused by an infection with a viral agent.	Pericarditis that is caused by an infection with a viral agent.	C34915	Pericarditis	C3439	Viral Infection	C90259	Pediatric Terminology		
C	C128406	Fungal Pericarditis	Fungal Pericarditis		Pericarditis that is caused by an infection with a fungal agent.	Pericarditis that is caused by an infection with a fungal agent.	C3245	Fungal Infection	C34915	Pericarditis	C90259	Pediatric Terminology		
C	C128407	Bacterial Peritonitis	Bacterial Peritonitis		Peritonitis that is caused by a bacterial infection.	Peritonitis that is caused by a bacterial infection.	C2890	Bacterial Infection	C26849	Peritonitis	C90259	Pediatric Terminology		
C	C128410	Rocky Mountain Spotted Fever	Rocky Mountain Spotted Fever		An infection that is caused by Rickettsia rickettsii, which is transmitted to humans from infected ticks; it is characterized by the sudden onset of fever, headache, and myalgia, followed by rash that usually begins peripherally.	An infection that is caused by Rickettsia rickettsii, which is transmitted to humans from infected ticks; it is characterized by the sudden onset of fever, headache, and myalgia, followed by rash that usually begins peripherally.	C3439	Viral Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128418	Lassa Fever	Lassa Fever		A viral hemorrhagic fever that is caused by the Lassa virus, which is transmitted by contact with infected rodents; it is characterized by fever, headache, malaise, myalgia, and hearing loss.	A viral hemorrhagic fever that is caused by the Lassa virus, which is transmitted by contact with infected rodents; it is characterized by fever, headache, malaise, myalgia, and hearing loss.	C36170	Viral Hemorrhagic Fever	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128419	Rift Valley Fever	Rift Valley Fever	RVF	A viral hemorrhagic fever that is caused by the Rift Valley fever virus, which is transmitted by mosquitoes and infected animals. The infection is typically asymptomatic or causes only mild illness, but can be associated with retinitis.	A viral hemorrhagic fever that is caused by the Rift Valley fever virus, which is transmitted by mosquitoes and infected animals. The infection is typically asymptomatic or causes only mild illness, but can be associated with retinitis.	C36170	Viral Hemorrhagic Fever	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128421	Monkeypox	Monkeypox		An infection that is caused by an Orthopoxvirus, which is transmitted by primates or rodents, and which is characterized by a prodromal syndrome of fever, chills, headache, myalgia, and lymphedema; initial symptoms are followed by a generalized papular rash that typically progresses from vesiculation through crusting over the course of two weeks.	An infection that is caused by an Orthopoxvirus, which is transmitted by primates or rodents, and which is characterized by a prodromal syndrome of fever, chills, headache, myalgia, and lymphedema; initial symptoms are followed by a generalized papular rash that typically progresses from vesiculation through crusting over the course of two weeks.	C3439	Viral Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128422	Chikungunya	Chikungunya		An infection that is caused by the Chikungunya virus, which is transmitted by mosquitoes; it is characterized by fever and severe arthralgia.	An infection that is caused by the Chikungunya virus, which is transmitted by mosquitoes; it is characterized by fever and severe arthralgia.	C3439	Viral Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128424	Middle East Respiratory Syndrome	Middle East Respiratory Syndrome	MERS	A viral respiratory infection that is caused by the MERS coronavirus (MERS-CoV), which most often manifests with moderate to severe respiratory symptoms, including productive cough and shortness of breath, which can progress to pneumonia and acute respiratory distress syndrome.	A viral respiratory infection that is caused by the MERS coronavirus (MERS-CoV), which most often manifests with moderate to severe respiratory symptoms, including productive cough and shortness of breath, which can progress to pneumonia and acute respiratory distress syndrome.	C3439	Viral Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128425	Anaplasmosis	Anaplasmosis		An infection that is caused by Anaplasma phagocytophilum, which is transmitted to humans by infected ticks; it is characterized by fever, headache, chills, and myalgia.	An infection that is caused by Anaplasma phagocytophilum, which is transmitted to humans by infected ticks; it is characterized by fever, headache, chills, and myalgia.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128427	Southern Tick-Associated Rash Illness	Southern Tick-Associated Rash Illness	Masters Disease|STARI	A putative Borrelia infection causing acute manifestations similar to Lyme disease, particularly erythema migrans, following the bite of the lone star tick, Amblyomma americanum.	A putative Borrelia infection causing acute manifestations similar to Lyme disease, particularly erythema migrans, following the bite of the lone star tick, Amblyomma americanum.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C128428	Infectious Hidradenitis	Infectious Hidradenitis		Hidradenitis that is caused by an infectious agent, usually a bacterium.	Hidradenitis that is caused by an infectious agent, usually a bacterium.	C112190	Hidradenitis	C26726	Infectious Disorder	C90259	Pediatric Terminology		
C	C128429	Hidradenitis Suppurativa	Hidradenitis Suppurativa		A chronic, suppurative inflammation of the apocrine sweat glands, that is characterized by clusters of bumps or sores.	A chronic, suppurative inflammation of the apocrine sweat glands, that is characterized by clusters of bumps or sores.	C112190	Hidradenitis	C36281	Integumentary System Finding	C90259	Pediatric Terminology		
C	C128434	Rhinosinusitis	Rhinosinusitis		Inflammation of the mucous membranes lining the nose and paranasal sinuses.	Inflammation of the mucous membranes lining the nose and paranasal sinuses.	C26726	Infectious Disorder	C35024	Sinusitis	C90259	Pediatric Terminology		
C	C128441	Carrión Disease	Carrión Disease	Carrion Disease	An infection that is caused by Bartonella bacilliformis, which is transmitted to humans from infected sandflies. The acute phase (Oroya Fever) is characterized by fever, headache, myalgia, enlargement of the lymph nodes, and anemia. The chronic phase (verruga peruana/Peruvian wart) is characterized by benign, eruptive lesions that are bleeding and pruritic, arthralgia, and malaise.	An infection that is caused by Bartonella bacilliformis, which is transmitted to humans from infected sandflies. The acute phase (Oroya Fever) is characterized by fever, headache, myalgia, enlargement of the lymph nodes, and anemia. The chronic phase (verruga peruana/Peruvian wart) is characterized by benign, eruptive lesions that are bleeding and pruritic, arthralgia, and malaise.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C26699	Bacterial Arthritis	Bacterial Arthritis	Septic Arthritis	The inflammation of one or more joints caused by a bacterial infection within the joint space. Symptoms include pain, stiffness, and decreased range of motion in the affected joint.	Joint inflammation that is caused by a bacterial infection within the joint space.	C2883	Arthritis	C2890	Bacterial Infection	C90259	Pediatric Terminology		
C	C28182	Rabies	Rabies		A life-threatening viral infection caused by the neurotropic Rabies virus. It is transmitted to humans usually from a bite by an infected dog. The initial signs and symptoms include malaise, fever, and headache, followed by the central nervous system manifestations which include abrupt behavioral changes. Paralysis, lethargy, and coma follow the behavioral changes.	An infection that is caused by the neurotropic Rabies virus, which is most often transmitted to humans via a bite by an infected animal.	C3439	Viral Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C2914	Vulvovaginal Candidiasis	Vulvovaginal Candidiasis	Vaginal Candidiasis	Infection of the vulva and vagina with a fungus of the genus CANDIDA.  It is a disease associated with HIV infection.	Candidiasis of the vulva and/or vagina.	C26711	Candidiasis	C27020	Female Reproductive System Disorder	C90259	Pediatric Terminology		
C	C3299	Infectious Otitis Externa	Infectious Otitis Externa	Outer Ear Infection|Swimmer's Ear	Inflammation of the anatomical structures of the outer ear and ear canal secondary to an infectious process. Bacterial etiology is most common, but fungal infection is also possible. Symptoms include erythema, edema, and pain.	Otitis externa that is caused by an infectious agent.	C79601	Otitis Externa	C26726	Infectious Disorder	C90259	Pediatric Terminology		
C	C34509	Viral Conjunctivitis	Viral Conjunctivitis		Conjunctivitis resulting from viral infection.	Conjunctivitis that is caused by a virus.	C83508	Infectious Conjunctivitis	C3439	Viral Infection	C90259	Pediatric Terminology		
C	C34520	Cysticercosis	Cysticercosis		A parasitic infection caused by the larval form of Taenia solium. It is a disseminated infection affecting the central nervous system, subcutaneous tissues, lungs, heart and liver. The most serious complications result from infection of the brain parenchyma. Patients may develop seizures, hydrocephalus, encephalopathy and meningoencephalitis.	A disseminated infection of tissues or organs that is caused by the larval stage of Taenia solium.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C34611	Filariasis	Filariasis		Infection by filarial worms.	Infections with nematodes of the superfamily Filarioidea that is of global importance. The presence of living worms in the body is mainly asymptomatic, but the death of adult worms leads to granulomatous inflammation and fibrosis.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C34638	Glanders	Glanders		A condition resulting from infection by Burkholderia mallei, which mainly affects horses.	A zoonotic infection that is caused by Burkholderia mallei, and that, in humans, may manifest in acute or chronic forms.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C34682	Congo-Crimean Hemorrhagic Fever	Crimean-Congo Hemorrhagic Fever	CCHF	A tick borne hemorrhagic fever resulting from infection by Nairovirus.	A viral hemorrhagic fever that is caused by the Crimean-Congo hemorrhagic fever virus, which is transmitted by ticks and infected humans.	C36170	Viral Hemorrhagic Fever	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C34767	Leishmaniasis	Leishmaniasis		A parasitic infection caused by protozoa of the genus Leishmania. It is transmitted to humans via the bite of sandflies. There are three main forms of the disease: cutaneous, mucocutaneous, and visceral leishmaniasis. Cutaneous leishmaniasis causes skin ulcers; mucocutaneous leishmaniasis causes destructive lesions of the mucous membranes of the nose, mouth, and throat; visceral leishmaniasis is the most severe form of the disease and is manifested with anemia, weight loss, hepatomegaly and splenomegaly.	A protozoan infection that is caused by members of the genus Leishmania, which is transmitted to humans via the bite of sandflies. There are three main forms of the disease: cutaneous, mucocutaneous, and visceral.	C34953	Protozoal Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C3477	Bacillary Angiomatosis	Bacillary Angiomatosis		A condition that is caused by infection with Bartonella, and which is characterized by vascular proliferation, usually in immunocompromised individuals.	An infection that is caused by Bartonella henselae or Bartonella quintana, which occurs primarily in immunocompromised persons; it is characterized by vascular lesions in the skin, subcutaneous tissue, bone, or other organs.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C34970	Q Fever	Q Fever		A bacterial infection caused by Coxiella burnetii. It is transmitted to humans by the inhalation of infected air particles or contact with fluids and feces of infected animals. Signs and symptoms include the abrupt onset of fever, headache, myalgias, and weakness.	An infection that is caused by Coxiella burnetii; it is transmitted to humans by the inhalation of infected air particles or contact with fluids and feces of infected animals. Signs and symptoms include the abrupt onset of fever, headache, myalgias, and weakness.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C34971	Rat-Bite Fever	Rat-Bite Fever	Spirillosis|Streptobacillosis	An infectious disease that is caused transmitted by the bite of a rat. Two species of bacteria can cause the infection: Streptobacillus moniliformis and Spirillum minus.	An acute infection that is caused by  Streptobacillus moniliformis (in North America) or Spirillum minus (in Asia), which is transmitted primarily by rodents; it is characterized by fever, myalgia, arthralgia, and petechial rash. When infections are acquired without a bite the resulting illness is called Haverhill Fever.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C34998	Scabies	Scabies		A contagious skin infection that is caused by the burrowing parasitic mite, Sarcoptes scabiei, and is characterized by intense itching and small, raised red spots in the area of the mite burrows.	A contagious infestation that is caused by the burrowing parasitic mite, Sarcoptes scabiei; it is characterized by intense itching and small, raised red spots in the area of the mite burrows.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C35050	Surgical Wound Infection	Surgical Wound Infection		Infection of a surgical incision.	Infection of a surgical incision.	C2959	Complication	C128320	Infection	C90259	Pediatric Terminology		
C	C35055	Syphilis	Syphilis		A contagious bacterial infection caused by the spirochete Treponema pallidum. It is a sexually transmitted disorder, although it can also be transmitted from the mother to the fetus in utero. Typically, it is initially manifested with a single sore which heals without treatment. If the infection is left untreated, the initial stage is followed by skin rash and mucous membrane lesions. A late stage follows, which is characterized by damage of the internal organs, including the nervous system.	An infection that is caused by the spirochete Treponema pallidum.	C26726	Infectious Disorder	C3365	Sexually Transmitted Infection	C90259	Pediatric Terminology		
C	C35124	Viral Hepatitis	Viral Hepatitis		An acute or chronic inflammation of the liver parenchyma caused by viruses. Representative examples include hepatitis A, B, and C, cytomegalovirus hepatitis, and herpes simplex hepatitis.	Hepatitis that is caused by a viral infection.	C3095	Hepatitis	C3439	Viral Infection	C90259	Pediatric Terminology		
C	C35374	Viral Gastroenteritis	Viral Gastroenteritis		Gastroenteritis resulting from a viral infection.	Gastroenteritis that is caused by an infection with a viral agent.	C34632	Gastroenteritis	C3439	Viral Infection	C90259	Pediatric Terminology		
C	C36171	Ebola Hemorrhagic Fever	Ebola	Ebola Hemorrhagic Fever	A viral hemorrhagic fever that is caused by the Ebola virus, which is transmitted by contact with infected animals or humans; it is characterized by high fever, unexplained bleeding, and a high mortality rate.	A viral hemorrhagic fever that is caused by the Ebola virus, which is transmitted by contact with infected animals or humans; it is characterized by high fever, unexplained bleeding, and a high mortality rate.	C36170	Viral Hemorrhagic Fever	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C45234	Wound Infection	Wound Infection		Infection of a break in the skin or other tissue.	Infection of a break in the skin or other tissue due to injury.	C128320	Infection	C26726	Infectious Disorder	C90259	Pediatric Terminology		
C	C50704	Postoperative Wound Infection	Postoperative Wound Infection		Infection of a surgical skin incision.	Infection of a surgical skin incision.	C2959	Complication	C128320	Infection	C90259	Pediatric Terminology		
C	C53656	Bacterial Conjunctivitis	Bacterial Conjunctivitis		Inflammation of the conjunctiva caused by a variety of bacterial agents.	Conjunctivitis that is caused by bacteria.	C2890	Bacterial Infection	C83508	Infectious Conjunctivitis	C90259	Pediatric Terminology		
C	C78265	Infective Endocarditis	Infective Endocarditis		An infectious process involving the endocardial layer of the heart.	Endocarditis that is caused by an infectious agent.	C34582	Endocarditis	C26726	Infectious Disorder	C90259	Pediatric Terminology		
C	C79550	Infectious Encephalitis	Infectious Encephalitis		An acute infectious process that affects the brain tissue. It is usually caused by viruses and less often by bacteria, parasites, and fungi.	Inflammation of the brain that is caused by an infectious agent.	C26760	Encephalitis	C26726	Infectious Disorder	C90259	Pediatric Terminology		
C	C83508	Infectious Conjunctivitis	Infectious Conjunctivitis		An infectious process affecting the conjunctiva.	Conjunctivitis that is caused by an infectious agent.	C34504	Conjunctivitis	C26726	Infectious Disorder	C90259	Pediatric Terminology		
C	C84565	Anthrax	Anthrax		An infection caused by Bacillus anthracis bacteria. It may affect the lungs, gastrointestinal tract, or skin. Patients with lung infection present with fever, headaches, cough, chest pain and shortness of breath. Patients with gastrointestinal infection present with nausea, vomiting and bloody diarrhea. Patients with skin infection develop blisters and ulcers.	An infection that is caused by Bacillus anthracis, which is usually acquired by contact with infected animals, contaminated animal products, or directly from soil; it may affect the lungs, gastrointestinal tract, skin, and/or central nervous system.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C84581	Babesiosis	Babesiosis		A parasitic infection caused by Babesia. It is transmitted by ticks and infects the red blood cells. Signs and symptoms include fever, fatigue and hemolytic anemia.	A malaria-like, tickborne, protozoan zoonosis that is caused by Babesia.	C34953	Protozoal Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C84583	Balantidiasis	Balantidiasis		A parasitic protozoal infection caused by Balantidium coli that involves the large intestinal mucosa. Signs and symptoms include nausea, vomiting, diarrhea, abdominal pain, fever, headache and weight loss.	A protozoan intestinal infection that is caused by Balantidium coli; the symptoms may include watery diarrhea or dysentery, and the spectrum of illness ranges from asymptomatic infection to fulminant and fatal disease.	C34953	Protozoal Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C84620	Cat-Scratch Disease	Cat-Scratch Disease	Cat-Scratch Fever	A bacterial infection caused by Bartonella henselae. It is transmitted to humans from a scratch, bite, or lick from a cat. A blister or a bump appears on the skin following the scratch or bite. Subsequently, there is lymph node enlargement around the scratch or bite site. The lymph node enlargement most often occurs under the arm or the neck. Some patients experience fever, fatigue, headaches or sore throat as well.	An infection that is caused by Bartonella henselae, which is transmitted to humans from a scratch, bite, or lick from an infected cat. A local, erythematous papule or blister may appear on the skin. Patients characteristically come to medical attention for lymph node enlargement, for fever, or, rarely, for central nervous system symptoms.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C84629	Chagas Disease	Chagas Disease	American Trypanosomiasis	A parasitic infection caused by Trypanosoma cruzi. It is transmitted by insect bites. It is characterized by an acute and chronic phase; in the acute phase patients may have fever, malaise, and swelling at the site of the insect bite. In the chronic phase patients develop hepatosplenomegaly, lymphadenopathy, cardiomyopathy and arrhythmias.	A protozoan infection that is caused by Trypanosoma cruzi; it is transmitted by triatomine insects, and is characterized by acute (fever and local swelling) and chronic (hepatosplenomegaly, lymphadenopathy, cardiomyopathy) phases.	C34953	Protozoal Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C84682	Echinococcosis	Echinococcosis		A parasitic infection caused by tapeworm larvae of Echinococcus. It affects livestock and humans. It is characterized by the formation of hydatid cysts mainly in the liver, lungs, spleen, and kidneys. Rupture of the cysts may lead to shock.	An infection that is caused by tapeworm larvae of Echinococcus. It is characterized by the formation of hydatid cysts, mainly in the liver, lungs, spleen, and kidneys.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C84688	Endemic Typhus Fever	Endemic Typhus	Endemic Flea-Borne Typhus	A bacterial infection caused by Rickettsia typhi or Rickettsia felis. It is transmitted to humans from infected rat fleas. Symptoms include fever, headache, joint and muscle pain, and weakness.	An infection that is caused by Rickettsia typhi or Rickettsia felis, which is transmitted to humans from infected rat fleas; symptoms include fever, headache, joint and muscle pain, and weakness.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C84689	Epidemic Louse-Borne Typhus	Epidemic Typhus	Epidemic Louse-Borne Typhus	A gram-negative bacterial infection caused by Rickettsia prowazekii. It is spread by lice infected with the bacteria. Signs and symptoms include sudden headache, generalized muscle pain, malaise, and macular skin lesions. The infection may affect the central nervous system causing encephalitis.	An infection that is caused by Rickettsia prowazekii, which is transmitted to humans from infected lice; manifestations include sudden headache, generalized muscle pain, malaise, macular skin lesions, and encephalitis.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C84747	Hantavirus Pulmonary Syndrome	Hantavirus Pulmonary Syndrome		An infection caused by Hantaviruses. It manifests with flu-like symptoms but it rapidly progresses to life-threatening respiratory problems.	An infection that is caused by a wide variety of new world Hantaviruses, which is transmitted after contact with infected rodents; it manifests with flu-like symptoms that rapidly progress to pneumonia and acute respiratory distress syndrome.	C3439	Viral Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C84824	Leprosy	Leprosy	Hansen Disease	A bacterial granulomatous infection caused by Mycobacterium leprae. It is a progressive disease affecting the skin, peripheral nerves, and limbs. If untreated, it causes permanent tissue damage leading to autoamputations.	An infection predominantly that is caused by Mycobacterium leprae, which causes a progressive disease affecting the skin, peripheral nerves, and limbs. If untreated, it usually causes permanent tissue damage leading to autoamputations.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C84883	Marburg Virus Disease	Marburg Hemorrhagic Fever		A viral infectious disorder caused by Marburg virus. Signs and symptoms include fever, headache, myalgias, chest and abdominal pain, jaundice, liver failure, massive hemorrhaging, and multiple organ failure.	A viral hemorrhagic fever that is caused by the Marburg virus, which is transmitted by contact with infected animals and humans; it is characterized by maculopapular rash, early and late organ phases, and high mortality.	C36170	Viral Hemorrhagic Fever	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C84916	Necrotizing Fasciitis	Necrotizing Fasciitis		Infection of the deep skin and subcutaneous tissues and necrosis of the fascia. It is caused by bacteria including group A streptococcus, Staphylococcus aureus and Clostridium perfringens. It may develop following trauma and invasive procedures.	Infection and necrosis of the fascia and adjoining tissues.	C26726	Infectious Disorder	C107377	Musculoskeletal System Disorder	C90259	Pediatric Terminology		
C	C84932	Neurocysticercosis	Neurocysticercosis		A parasitic infection with tapeworms of the genus Taenia affecting the brain. It is manifested with seizures and headaches.	A central nervous system infection that results from the inactive parenchymal or ventricular stage of Taenia solium. While many infections are asymptomatic, seizures are the most common symptom.	C34520	Cysticercosis	C26835	Nervous System Disorder	C90259	Pediatric Terminology		
C	C84935	Neurosyphilis	Neurosyphilis		Infection of the brain or spinal cord by Treponema pallidum. It occurs many years following the original infection which remained untreated. Signs and symptoms include abnormal gait, blindness, depression, paralysis, seizures and dementia.	Infection of the brain or spinal cord by Treponema pallidum; it most commonly occurs in the tertiary stage but may occur at any stage.	C26835	Nervous System Disorder	C35055	Syphilis	C90259	Pediatric Terminology		
C	C84995	Paragonimiasis	Paragonimiasis		A parasitic infection caused by trematodes of the Paragonimus genus. Humans are infected from ingestion of raw or undercooked food. It results in chronic lung infection and eosinophilia.	A parasitic infection that is caused by trematodes of the Paragonimus genus. Humans are infected from ingestion of raw or undercooked food, which results in chronic lung infection and eosinophilia.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C85015	Plague	Plague		A Gram-negative bacterial infection caused by Yersinia pestis. It is usually transmitted to humans from bites of infected rodent fleas. It is manifested as a bubonic, septicemic, or pneumonic plague. In bubonic plague, the lymph nodes adjacent to the site of the skin bite are infected and enlarged. In septicemic plague, the infection spreads directly through the bloodstream. In pneumonic plague, the infection spreads to the lungs either following bubonic plague, or by inhalation of infective droplets. If untreated, it may lead to death.	An infection that is caused by Yersinia pestis, which is usually transmitted to humans from infected rodent fleas. It is manifested as a bubonic (lymph node), pneumonic, or septicemic plague. In bubonic plague, the lymph nodes adjacent to the site of the skin bite are infected and enlarged. In pneumonic plague, the infection spreads to the lungs, either following bubonic plague or by inhalation of infective droplets. The term septicemic plague is used when the primary manifestation is a bloodstream infection.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C85064	Severe Acute Respiratory Syndrome	Severe Acute Respiratory Syndrome	SARS	A viral respiratory infection caused by the SARS coronavirus. It is transmitted through close person-to-person contact. It is manifested with high fever, headache, dry cough and myalgias. It may progress to pneumonia and cause death.	A viral respiratory infection that is caused by the SARS-associated coronavirus (SARS-CoV), which is transmitted through close person-to-person contact; it manifests with high fever, headache, dry cough, and a high mortality rate.	C3439	Viral Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C85180	Taeniasis	Taeniasis		A parasitic infection caused by tapeworms of the genus Taenia. Humans are infected by eating undercooked or raw meat of infected animals. It is usually an asymptomatic infection and patients may become aware of the infection by noticing segments of the tapeworm in their feces. If symptoms are present, they include nausea, abdominal pain, indigestion, constipation, or diarrhea.	Intestinal infection with a human tapeworm (Taenia saginata, T. solium, T. asiatica), which is acquired by consumption of cysticerci in raw or undercooked food. Most infected people are asymptomatic and typically become aware of an infection via passing tapeworm segments in feces.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C85194	Toxocariasis	Toxocariasis		A parasitic infection caused by Toxocara. Humans are infected by the larvae of Toxocara canis and Toxocara cati from dogs and cats respectively. Most cases remain asymptomatic. The parasites may affect the eye, causing diminished vision, or other major organs, causing hepatomegaly, eosinophilia, wheezing, and coughing.	An infection that is caused by the larvae of Toxocara canis (dogs) or Toxocara cati (cats), most cases of which remain asymptomatic. The larvae can infect the eye, causing diminished vision, or other major organs, causing hepatomegaly, eosinophilia, coughing, and wheezing.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C85199	Trichinosis	Trichinosis	Trichinellosis	A parasitic infection caused by larvae of worms of the genus Trichinella. It is transmitted to humans by ingesting raw or undercooked meat from infected animals. Signs and symptoms include abdominal discomfort, nausea, vomiting, fever, diarrhea, headache, coughing, myalgias, arthralgias, and eye swelling.	An illness caused by the ingestion of larvae of roundworms of the genus Trichinella.	C27864	Parasitic Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C85208	Tularemia	Tularemia		A serious Gram-negative bacterial infection caused by Francisella tularensis. It is transmitted to humans through bites from infected insects, inhaling airborne bacteria, handling infected animals, or consuming contaminated food or water. Signs and symptoms include skin ulcers, mouth sores, lymphadenopathy, sore throat, fever and pneumonia.	An infection that is caused by Francisella tularensis, which is transmitted to humans from infected insects, inhaling airborne bacteria, handling infected animals, or consuming contaminated food or water; infection can manifest as fever, sore throat, skin ulcers, mouth sores, lymphadenopathy, or pneumonia.	C2890	Bacterial Infection	C35803	Zoonotic Infection	C90259	Pediatric Terminology		
C	C92950	Gonorrhea	Gonorrhea	GC	A common sexually transmitted bacterial infection caused by Neisseria gonorrhoeae. It is transmitted through vaginal, oral, or anal intercourse. Infected individuals may be asymptomatic. Symptoms in males include burning sensation during urination, discharge from the penis, and painful swelling of the testes. Symptoms in females include painful urination, vaginal discharge, and vaginal bleeding between periods. If untreated, the infection may lead to pelvic inflammatory disease.	A urogenital infection that is caused by Neisseria gonorrhoeae.	C2890	Bacterial Infection	C3365	Sexually Transmitted Infection	C90259	Pediatric Terminology		
C	C116816	Gonococcal Ophthalmia Neonatorum	Gonococcal Conjunctivitis	Conjunctivitis Gonococcal	Inflammation of the conjunctiva in a newborn due to Neisseria gonorrhoeae which was acquired during labor and delivery.	Inflammation of the conjunctiva in a newborn due to Neisseria gonorrhoeae which was acquired during labor and delivery.	C53656	Bacterial Conjunctivitis	C99231	Neonatal Infectious Disorder	C90259	Pediatric Terminology		
C	C116817	Neonatal Chlamydia Conjunctivitis	Chlamydial Conjunctivitis	Inclusion Conjunctivitis|Trachoma	Inflammation of the conjunctiva in a newborn due to Chlamydia trachomatis which was acquired during labor and delivery.	Inflammation of the conjunctiva in a newborn due to Chlamydia trachomatis which was acquired during labor and delivery.	C53656	Bacterial Conjunctivitis	C99231	Neonatal Infectious Disorder	C90259	Pediatric Terminology		
C	C116973	Bacterial Vaginosis	Bacterial Vaginosis	BV	Infection caused by bacterial overgrowth in the vagina. Most affected women are asymptomatic. When symptoms occur, they include foul-smelling vaginal discharge, vaginal itching, and burning. Risk factors include sexual activity with multiple partners and the use of vaginal douches and intrauterine devices. Up to a third of cases resolve without treatment. Antibiotic treatment is recommended when symptoms are present and for women that are pregnant at the time of infection.	Bacterial overgrowth in the vagina that may be asymptomatic or that may cause foul-smelling vaginal discharge, vaginal itching, and burning.	C2890	Bacterial Infection			C90259	Pediatric Terminology		
C	C128168	Contact Transmission	Contact Transmission		The transmission of an infectious agent via touch.	The transmission of an infectious agent via touch.	C128376	Mode of Transmission			C90259	Pediatric Terminology		
C	C128169	Direct Transmission	Direct Transmission	Direct Contact Transmission	The transmission of an infectious agent from a source (e.g., person, animal, or surface) to a host without an intermediary.	The transmission of an infectious agent from a source (e.g., person, animal, or surface) to a host without an intermediary.	C128376	Mode of Transmission			C90259	Pediatric Terminology		
C	C128170	Indirect Transmission	Indirect Transmission	Indirect Contact Transmission	The transmission of an infectious agent from a source to a host through an intermediary such as inanimate objects (vehicles) or living organisms (vectors).	The transmission of an infectious agent from a source to a host through an intermediary such as inanimate objects (vehicles) or living organisms (vectors).	C128376	Mode of Transmission			C90259	Pediatric Terminology		
C	C128320	Infection	Infection		The invasion of an organism's body tissues by disease-causing agents and their multiplication, as well as the reaction by the host to these organisms and/or toxins that the organisms produce.	The invasion of an organism's body tissues by disease-causing agents and their multiplication, as well as the reaction by the host to these organisms and/or toxins that the organisms produce.	C3367	Finding			C90259	Pediatric Terminology		
C	C128322	Peritonsillar Abscess	Peritonsillar Abscess		An abscess that develops in the space surrounding one or both palatine tonsils.	An abscess that develops in the space surrounding one or both palatine tonsils.	C26686	Abscess			C90259	Pediatric Terminology		Quinsy
C	C128323	Parapharyngeal Abscess	Parapharyngeal Abscess	Lateral Pharyngeal Abscess	An abscess that develops in the soft tissues of the lateral pharyngeal space.	An abscess that develops in the soft tissues of the lateral pharyngeal space.	C26686	Abscess			C90259	Pediatric Terminology		
C	C128324	Retropharyngeal Abscess	Retropharyngeal Abscess		An abscess that develops in the soft tissues behind the posterior pharyngeal wall.	An abscess that develops in the soft tissues behind the posterior pharyngeal wall.	C26686	Abscess			C90259	Pediatric Terminology		
C	C128325	Prevertebral Abscess	Prevertebral Abscess		An abscess that develops in the tissues within the prevertebral fascia.	An abscess that develops in the tissues within the prevertebral fascia.	C26686	Abscess			C90259	Pediatric Terminology		
C	C128326	Intra-abdominal Abscess	Intra-abdominal Abscess		An abscess within the abdomen.	An abscess within the abdomen.	C26686	Abscess			C90259	Pediatric Terminology		
C	C128327	Subdiaphragmatic Abscess	Subdiaphragmatic Abscess	Subphrenic Abscess	An abscess that is located in the anatomical space between the diaphragm and the liver and/or spleen.	An abscess that is located in the anatomical space between the diaphragm and the liver and/or spleen.	C26686	Abscess			C90259	Pediatric Terminology		
C	C128328	Mesenteric Abscess	Mesenteric Abscess		An abscess that is located in any part of the tissue composing the mesentery, and that generally arises from an infection in an adjacent area of the intestine.	An abscess that is located in any part of the tissue composing the mesentery, and that generally arises from an infection in an adjacent area of the intestine.	C26686	Abscess			C90259	Pediatric Terminology		
C	C128329	Perihepatic Abscess	Perihepatic Abscess		An abscess that is located in the anatomical space surrounding the liver, but which is outside of the liver capsule itself.	An abscess that is located in the anatomical space surrounding the liver, but which is outside of the liver capsule itself.	C26686	Abscess			C90259	Pediatric Terminology		
C	C128330	Retroperitoneal Abscess	Retroperitoneal Abscess		An abscess that is located in the abdominal cavity posterior to the peritoneum.	An abscess that is located in the abdominal cavity posterior to the peritoneum.	C26686	Abscess			C90259	Pediatric Terminology		
C	C128331	Pelvic Abscess	Pelvic Abscess		An abscess that is located in the pelvic cavity.	An abscess that is located in the pelvic cavity.	C26686	Abscess			C90259	Pediatric Terminology		
C	C128332	Reactive Arthritis	Reactive Arthritis		A form of inflammatory arthritis that results as a reaction to a bacterial infection outside the joint.	A form of inflammatory arthritis that results as a reaction to a bacterial infection outside the joint.	C2883	Arthritis			C90259	Pediatric Terminology		
C	C128333	Migratory Arthritis	Migratory Arthritis		A form of reactive arthritis in which the inflammation moves between joints.	A form of reactive arthritis in which the inflammation moves between joints.	C2883	Arthritis			C90259	Pediatric Terminology		
C	C128334	Legionellosis	Legionellosis		Any disease caused by Legionella bacteria.	Any disease caused by Legionella bacteria.	C2890	Bacterial Infection			C90259	Pediatric Terminology		
C	C128335	Pontiac Fever	Pontiac Fever		A self-limited, febrile illness without pneumonia that occurs in epidemics, and that is caused by Legionella species.	A self-limited, febrile illness without pneumonia that occurs in epidemics, and that is caused by Legionella species.	C2890	Bacterial Infection			C90259	Pediatric Terminology		
C	C128336	Melioidosis	Melioidosis	Whitmore Disease	An infection that is caused by Burkholderia pseudomallei, which is found in soil and water; symptoms vary widely, but most commonly include fever, cough, pneumonia, arthralgia, myalgia, and skin ulceration.	An infection that is caused by Burkholderia pseudomallei, which is found in soil and water; symptoms vary widely, but most commonly include fever, cough, pneumonia, arthralgia, myalgia, and skin ulceration.	C2890	Bacterial Infection			C90259	Pediatric Terminology		
C	C128338				Historical term that references a form of pneumonia caused by Mycoplasma pneumoniae, Chlamydophila pneumoniae, or Legionella species.	Historical term that references a form of pneumonia caused by Mycoplasma pneumoniae, Chlamydophila pneumoniae, or Legionella species.	C3333	Pneumonia			C90259	Pediatric Terminology	Atypical Pneumonia	Walking Pneumonia
C	C128339	Legionella Pneumonia	Legionella Pneumonia	Legionnaires' Disease	A pneumonia caused by Legionella pneumophila and other Legionella species, which is characterized by fever, cough, progressive respiratory distress, and which is often accompanied by extrapulmonary manifestations.	A pneumonia caused by Legionella pneumophila and other Legionella species, which is characterized by fever, cough, progressive respiratory distress, and which is often accompanied by extrapulmonary manifestations.	C3333	Pneumonia			C90259	Pediatric Terminology		
C	C128341	Foodborne Botulism	Foodborne Botulism		Botulism that is caused by consuming food or beverage that contains the botulinum toxin.	Botulism that is caused by consuming food or beverage that contains the botulinum toxin.	C84599	Botulism			C90259	Pediatric Terminology		
C	C128342	Wound Botulism	Wound Botulism		Botulism that is caused by toxin that is produced in a wound contaminated with Clostridium botulinum.	Botulism that is caused by toxin that is produced in a wound contaminated with Clostridium botulinum.	C84599	Botulism			C90259	Pediatric Terminology		
C	C128343	Infant Botulism	Infant Botulism		Botulism that is caused by contact with spores of Clostridial bacteria, which subsequently grow in the intestine and release toxin.	Botulism that is caused by contact with spores of Clostridial bacteria, which subsequently grow in the intestine and release toxin.	C84599	Botulism			C90259	Pediatric Terminology		
C	C128344	Adult Intestinal Botulism	Adult Intestinal Botulism	Adult Intestinal Toxemia Botulism	A rare form of botulism that occurs among adults by the same mechanism as infant botulism.	A rare form of botulism that occurs among adults by the same mechanism as infant botulism.	C84599	Botulism			C90259	Pediatric Terminology		
C	C128345	Iatrogenic Botulism	Iatrogenic Botulism	Accidental Botulism	Botulism that occurs following injection of botulinum toxin.	Botulism that occurs following injection of botulinum toxin.	C84599	Botulism			C90259	Pediatric Terminology		
C	C128346	Prion Disease	Prion Disease		A transmissible, infectious disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal.	A transmissible, infectious disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal.	C26726	Infectious Disorder			C90259	Pediatric Terminology		
C	C128347	Antibiotic-Associated Colitis	Antibiotic-Associated Colitis		Inflammation of the colon that is caused by an alteration in intestinal flora by antibiotic use.	Inflammation of the colon that is caused by an alteration in intestinal flora by antibiotic use.	C26723	Colitis			C90259	Pediatric Terminology		
C	C128348	Fecal-Oral Transmission	Fecal-Oral Transmission		The transmission of an infectious agent to a host's oral cavity via the fecal particles of another living organism.	The transmission of an infectious agent to a host's oral cavity via the fecal particles of another living organism.	C128376	Mode of Transmission			C90259	Pediatric Terminology		
C	C128349	Cercarial Dermatitis	Cercarial Dermatitis	Duck Itch|Lake Itch|Swimmer's Itch	A pruritic rash that occurs as consequence of cercariae penetration of the skin after aquatic exposure to animal (usually avian) schistosomes, often in countries non-endemic to human schistosomiasis. The condition is non-invasive and responsive to symptomatic treatment.	A pruritic rash that occurs as consequence of cercariae penetration of the skin after aquatic exposure to animal (usually avian) schistosomes, often in countries non-endemic to human schistosomiasis. The condition is non-invasive and responsive to symptomatic treatment.	C3371	Skin Disorder			C90259	Pediatric Terminology		
C	C128350	Antibiotic-Associated Diarrhea	Antibiotic-Associated Diarrhea		Diarrhea that is associated with current or recent antibiotic use.	Diarrhea that is associated with current or recent antibiotic use.	C2987	Diarrhea			C90259	Pediatric Terminology		
C	C128351	Foodborne Illness	Foodborne Illness	Food Poisoning	Any disorder that results from the consumption of food contaminated with an infectious agent or toxin.	Any disorder that results from the consumption of food contaminated with an infectious agent or toxin.	C26726	Infectious Disorder			C90259	Pediatric Terminology		
C	C128352	Droplet Transmission	Droplet Transmission	Droplet Spread	The direct transmission of an infectious agent to a host by a spray of a relatively large (greater than five microns), short range respiratory aerosol.	The direct transmission of an infectious agent to a host by a spray of a relatively large (greater than five microns), short range respiratory aerosol.	C128376	Mode of Transmission			C90259	Pediatric Terminology		
C	C128353	Airborne Transmission	Airborne Transmission		The direct transmission of an infectious agent to a host via droplet nuclei (less than or equal to five microns) or dust suspended in the air.	The direct transmission of an infectious agent to a host via droplet nuclei (less than or equal to five microns) or dust suspended in the air.	C128376	Mode of Transmission			C90259	Pediatric Terminology		
C	C128354	Arthropod Vector	Arthropod Vector		An animal within the phylum Arthropoda that transmits an infectious agent to a vertebrate animal.	An animal within the phylum Arthropoda that transmits an infectious agent to a vertebrate animal.	C14198	Vector			C90259	Pediatric Terminology		
C	C128355	Native Valve Endocarditis	Native Valve Endocarditis		Endocarditis affecting a native valve of the heart.	Endocarditis affecting a native valve of the heart.	C34582	Endocarditis			C90259	Pediatric Terminology		
C	C128356	Prosthetic Valve Endocarditis	Prosthetic Valve Endocarditis		Endocarditis occurring on parts of a valve prosthesis or a reconstructed heart valve; it can be classified into early and late prosthetic valve endocarditis.	Endocarditis occurring on parts of a valve prosthesis or a reconstructed heart valve; it can be classified into early and late prosthetic valve endocarditis.	C34582	Endocarditis			C90259	Pediatric Terminology		
C	C128357	Early Prosthetic Valve Endocarditis	Early Prosthetic Valve Endocarditis		Prosthetic valve endocarditis that occurs days to weeks after surgery.	Prosthetic valve endocarditis that occurs days to weeks after surgery.	C128356	Prosthetic Valve Endocarditis			C90259	Pediatric Terminology		
C	C128358	Late Prosthetic Valve Endocarditis	Late Prosthetic Valve Endocarditis		Prosthetic valve endocarditis that occurs several months to years following valve replacement.	Prosthetic valve endocarditis that occurs several months to years following valve replacement.	C128356	Prosthetic Valve Endocarditis			C90259	Pediatric Terminology		
C	C128359	Bacterial Endocarditis	Bacterial Endocarditis		Endocarditis that is caused by an infection with a bacterial agent.	Endocarditis that is caused by an infection with a bacterial agent.	C34582	Endocarditis			C90259	Pediatric Terminology		
C	C128360	Lymphatic Filariasis	Lymphatic Filariasis	Elephantiasis	A clinical disorder that is caused by obstruction of the lymphatic system years after filarial infection. It is characterized by painful and profound lymphedema, resulting in significant swelling (elephantiasis) of extremities and genitals.	A clinical disorder that is caused by obstruction of the lymphatic system years after filarial infection. It is characterized by painful and profound lymphedema, resulting in significant swelling (elephantiasis) of extremities and genitals.	C27864	Parasitic Infection			C90259	Pediatric Terminology		
C	C128361	Colonization	Colonization		The presence of microorganisms (not contamination) on a body surface, including the skin and mucosal surfaces (e.g., respiratory, gastrointestinal, and urogenital tracts). Colonization implies the lack of signs or symptoms of infection but often precedes infection.	The presence of microorganisms (not contamination) on a body surface, including the skin and mucosal surfaces (e.g., respiratory, gastrointestinal, and urogenital tracts). Colonization implies the lack of signs or symptoms of infection but often precedes infection.	C3367	Finding			C90259	Pediatric Terminology		
C	C128362	Dimorphic Fungus	Dimorphic Fungus		A fungus that grows as either a yeast or a mold.	A fungus that grows as either a yeast or a mold.	C14209	Fungus			C90259	Pediatric Terminology		
C	C128363	Interferon-Gamma Release Assay	Interferon-Gamma Release Assay	IGRA	A blood test that exposes a person's lymphocytes ex vivo to two or three Mycobacterium tuberculosis-specific antigens; a positive result suggests that the person has tuberculosis infection.	A blood test that exposes a person's lymphocytes ex vivo to two or three Mycobacterium tuberculosis-specific antigens; a positive result suggests that the person has tuberculosis infection.	C25294	Laboratory Procedure			C90259	Pediatric Terminology		
C	C128364	Vehicle Transmission	Vehicle Transmission		The indirect transmission of an infectious agent to a host via inanimate objects such as food, water, biologic products, or fomites.	The indirect transmission of an infectious agent to a host via inanimate objects such as food, water, biologic products, or fomites.	C128376	Mode of Transmission			C90259	Pediatric Terminology		
C	C128365	Vector Transmission	Vector Transmission		The indirect transmission of an infectious agent to a host via another living organism, either through purely mechanical means (e.g., insect bite) or by that organism supporting the growth or changes in the agent that make it infectious to the host.	The indirect transmission of an infectious agent to a host via another living organism, either through purely mechanical means (e.g., insect bite) or by that organism supporting the growth or changes in the agent that make it infectious to the host.	C128376	Mode of Transmission			C90259	Pediatric Terminology		
C	C128367	Endogenous Infection	Endogenous Infection	Auto-Infection	An infection caused by an infectious agent that is present on or in the host prior to the start of the infection.	An infection caused by an infectious agent that is present on or in the host prior to the start of the infection.	C128320	Infection			C90259	Pediatric Terminology		
C	C128368	Mastoiditis	Mastoiditis		Inflammation of the mucosal lining of the mastoid antrum and mastoid air cell system of the mastoid process.	Inflammation of the mucosal lining of the mastoid antrum and mastoid air cell system of the mastoid process.	C118420	Otolaryngologic Disorder			C90259	Pediatric Terminology		
C	C128369	Labyrinthitis	Labyrinthitis		Inflammation of the inner ear.	Inflammation of the inner ear.	C118420	Otolaryngologic Disorder			C90259	Pediatric Terminology		
C	C128371	Late Latent Syphilis	Late Latent Syphilis		Latent syphilis when infection was acquired more than twelve months previously.	Latent syphilis when infection was acquired more than twelve months previously.	C35056	Latent Syphilis			C90259	Pediatric Terminology		
C	C128372	Severe Malaria	Severe Malaria	Complicated Malaria	Acute malaria with signs of organ dysfunction, severe anemia (hemoglobin less than 5 g/dL or hematocrit less than 15%) and/or hyperparasitemia (greater than 5% of red blood cells infected).	Acute malaria with signs of organ dysfunction, severe anemia (hemoglobin less than 5 g/dL or hematocrit less than 15%) and/or hyperparasitemia (greater than 5% of red blood cells infected).	C34797	Malaria			C90259	Pediatric Terminology		
C	C128373	Cerebral Malaria	Cerebral Malaria		A sequestration of Plasmodium falciparum in the brain, which can cause coma and/or seizures.	A sequestration of Plasmodium falciparum in the brain, which can cause coma and/or seizures.	C34797	Malaria			C90259	Pediatric Terminology		
C	C128374	Eosinophilic Meningitis	Eosinophilic Meningitis		Meningitis in which eosinophils predominate in the cerebrospinal fluid.	Meningitis in which eosinophils predominate in the cerebrospinal fluid.	C26828	Meningitis			C90259	Pediatric Terminology		
C	C128376	Mode of Transmission	Mode of Transmission		The process by which an infection is transmitted to a person.	The process by which an infection is transmitted to a person.	C20189	Property or Attribute			C90259	Pediatric Terminology		
C	C128377	Tuberculosis Infection	Tuberculosis Infection	LTBI|Latent Tuberculosis Infection	The asymptomatic presence of Mycobacterium tuberculosis in the body, which is determined by a positive result to a tuberculin skin test or interferon-gamma release assay.	The asymptomatic presence of Mycobacterium tuberculosis in the body, which is determined by a positive result to a tuberculin skin test or interferon-gamma release assay.	C2890	Bacterial Infection			C90259	Pediatric Terminology		
C	C128378	Acute Transverse Myelitis	Acute Transverse Myelitis		A neurologic disorder that is caused by inflammation across both sides of one level, or segment, of the spinal cord. (from NINDS)	A neurologic disorder that is caused by inflammation across both sides of one level, or segment, of the spinal cord. (from NINDS)	C26832	Myelitis			C90259	Pediatric Terminology		
C	C128379	Acute Flaccid Myelitis	Acute Flaccid Myelitis		An acute onset of focal limb weakness that is associated mainly with gray matter abnormalities or CSF pleocytosis, but which is without an apparent cause.	An acute onset of focal limb weakness that is associated mainly with gray matter abnormalities or CSF pleocytosis, but which is without an apparent cause.	C26832	Myelitis			C90259	Pediatric Terminology		
C	C128384	Collapsed Lung	Collapsed Lung		Atelectasis of an entire lung.	Atelectasis of an entire lung.	C3198	Lung Disorder			C90259	Pediatric Terminology		
C	C128385	Uvulitis	Uvulitis		Inflammation of the uvula.	Inflammation of the uvula.	C118420	Otolaryngologic Disorder			C90259	Pediatric Terminology		
C	C128386	Chronic Suppurative Otitis Media	Chronic Suppurative Otitis Media	CSOM	Otitis media that persists for at least six weeks, and that is associated with otorrhea through a perforated tympanic membrane.	Otitis media that persists for at least six weeks, and that is associated with otorrhea through a perforated tympanic membrane.	C34885	Otitis Media			C90259	Pediatric Terminology		
C	C128396	Enterobiasis	Enterobiasis	Pinworm Infection|Threadworm Infection	An infection that is caused by the nematode Enterobius vermicularis; it is characterized predominantly by perianal pruritus.	An infection that is caused by the nematode Enterobius vermicularis; it is characterized predominantly by perianal pruritus.	C27864	Parasitic Infection			C90259	Pediatric Terminology		
C	C128398	Strongyloidiasis	Strongyloidiasis		An infection that is caused by nematodes of the genus Strongyloides, most commonly Strongyloides stercoralis, which is a soil-transmitted helminth, and which is characterized by a variety of gastrointestinal, dermatologic, and, occasionally, pulmonary manifestations. The worm's autoinfective life cycle can lead to hyper-infection and life-threatening dissemination in immunocompromised hosts decades after initial infection.	An infection that is caused by nematodes of the genus Strongyloides, most commonly Strongyloides stercoralis, which is a soil-transmitted helminth, and which is characterized by a variety of gastrointestinal, dermatologic, and, occasionally, pulmonary manifestations. The worm's autoinfective life cycle can lead to hyper-infection and life-threatening dissemination in immunocompromised hosts decades after initial infection.	C27864	Parasitic Infection			C90259	Pediatric Terminology		
C	C128401	Pediculosis	Pediculosis	Lice Infestation	A contagious infestation of parasitic insects found on the head (Pediculus humanus capitis), body (Pediculus humanus corporis), or pubic area (Pthirus pubis) that typically cause itching and rash.	A contagious infestation of parasitic insects found on the head (Pediculus humanus capitis), body (Pediculus humanus corporis), or pubic area (Pthirus pubis) that typically cause itching and rash.	C27864	Parasitic Infection			C90259	Pediatric Terminology		
C	C128402	Herpetic Whitlow	Herpetic Whitlow		A painful blister of the periungual skin that is caused by herpes simplex virus type 1 or 2.	A painful blister of the periungual skin that is caused by herpes simplex virus type 1 or 2.	C3439	Viral Infection			C90259	Pediatric Terminology		
C	C128403	Suppurative Parotitis	Suppurative Parotitis		Parotitis that is caused by a bacterial agent.	Parotitis that is caused by a bacterial agent.	C114281	Parotitis			C90259	Pediatric Terminology		
C	C128408	Cryptosporidiosis	Cryptosporidiosis	Cryptosporidium Infection	An infection that is caused by Cryptosporidium parvum or hominis, which is acquired by inhalation or ingestion of infectious spores, and which typically manifests as acute enteritis.	An infection that is caused by Cryptosporidium parvum or hominis, which is acquired by inhalation or ingestion of infectious spores, and which typically manifests as acute enteritis.	C34953	Protozoal Infection			C90259	Pediatric Terminology		
C	C128409	Cyclosporiasis	Cyclosporiasis		A protozoan infection that is caused by Cyclospora cayetanensis, which is most commonly acquired from contaminated food or water, and which is characterized by watery diarrhea and abdominal pain.	A protozoan infection that is caused by Cyclospora cayetanensis, which is most commonly acquired from contaminated food or water, and which is characterized by watery diarrhea and abdominal pain.	C34953	Protozoal Infection			C90259	Pediatric Terminology		
C	C128411	Acute Sinusitis	Acute Sinusitis		Sinusitis lasting less than or equal to thirty days.	Sinusitis lasting less than or equal to thirty days.	C35024	Sinusitis			C90259	Pediatric Terminology		
C	C128412	Primary Syphilis	Primary Syphilis		The subclinical or symptomatic stage of syphilis, occurring at an average of three weeks after contact with an infected individual. It manifests with one or more painless, indurated ulcers (chancres) of the skin or mucous membranes at the site of inoculation. These lesions heal spontaneously within a few weeks.	The subclinical or symptomatic stage of syphilis, occurring at an average of three weeks after contact with an infected individual. It manifests with one or more painless, indurated ulcers (chancres) of the skin or mucous membranes at the site of inoculation. These lesions heal spontaneously within a few weeks.	C35055	Syphilis			C90259	Pediatric Terminology		
C	C128413	Secondary Syphilis	Secondary Syphilis		The secondary stage of syphilis typically that is characterized by generalized rash (including palms and soles), mucocutaneous lesions, and lymphadenopathy. It usually begins one to two months after the primary stage.	The secondary stage of syphilis typically that is characterized by generalized rash (including palms and soles), mucocutaneous lesions, and lymphadenopathy. It usually begins one to two months after the primary stage.	C35055	Syphilis			C90259	Pediatric Terminology		
C	C128414	Tertiary Syphilis	Tertiary Syphilis	Late Syphilis	A stage of syphilis that occurs fifteen to thirty years after the initial infection; it can include gumma formation and cardiovascular or central nervous system involvement (neurosyphilis).	A stage of syphilis that occurs fifteen to thirty years after the initial infection; it can include gumma formation and cardiovascular or central nervous system involvement (neurosyphilis).	C35055	Syphilis			C90259	Pediatric Terminology		
C	C128415	Multidrug-Resistant Tuberculosis	Multidrug-Resistant Tuberculosis	MDR-TB|Multidrug-Resistant TB	Tuberculosis disease that is caused by a multidrug-resistant strain of Mycobacterium tuberculosis.	Tuberculosis disease that is caused by a multidrug-resistant strain of Mycobacterium tuberculosis.	C3423	Tuberculosis			C90259	Pediatric Terminology		
C	C128416	Pre-Extensively Drug-Resistant Tuberculosis	Pre-Extensively Drug-Resistant Tuberculosis	Pre-Extensively Drug-Resistant TB|Pre-XDR-TB	Tuberculosis disease that is caused by a pre-extensively drug-resistant strain of Mycobacterium tuberculosis.	Tuberculosis disease that is caused by a pre-extensively drug-resistant strain of Mycobacterium tuberculosis.	C3423	Tuberculosis			C90259	Pediatric Terminology		
C	C128417	Extensively Drug-Resistant Tuberculosis	Extensively Drug-Resistant Tuberculosis	Extensively Drug-Resistant TB|XDR-TB	Tuberculosis disease that is caused by an extensively drug-resistant strain of Mycobacterium tuberculosis.	Tuberculosis disease that is caused by an extensively drug-resistant strain of Mycobacterium tuberculosis.	C3423	Tuberculosis			C90259	Pediatric Terminology		
C	C128420	Roseola Infantum	Roseola Infantum	Exanthem Subitum|Roseola	An infection that is due to human herpesvirus (HHV) types 6 or 7; it is characterized by 3-5 days of high fever followed by the acute onset of a rosy, pink, non-pruritic, macular rash that is predominantly on the neck and trunk.	An infection that is due to human herpesvirus (HHV) types 6 or 7; it is characterized by 3-5 days of high fever followed by the acute onset of a rosy, pink, non-pruritic, macular rash that is predominantly on the neck and trunk.	C3439	Viral Infection			C90259	Pediatric Terminology		
C	C128423	Zika Virus Infection	Zika		An infection that is caused by the Zika virus, which is primarily transmitted via mosquitoes; it is characterized by fever, skin rash, arthralgia, and conjunctivitis.	An infection that is caused by the Zika virus, which is primarily transmitted via mosquitoes; it is characterized by fever, skin rash, arthralgia, and conjunctivitis.	C3439	Viral Infection			C90259	Pediatric Terminology		
C	C128426	Louse-Borne Relapsing Fever	Louse-Borne Relapsing Fever		An infection that is caused by certain species of Rickettsia or Borrelia, which are transmitted to humans from infected lice; it is characterized by sudden fever, chills, headaches, myalgia, arthralgia, nausea, and possibly a rash. Symptoms usually persist for two to nine days, then disappear, with recurrence after several weeks if the patient remains untreated.	An infection that is caused by certain species of Rickettsia or Borrelia, which are transmitted to humans from infected lice; it is characterized by sudden fever, chills, headaches, myalgia, arthralgia, nausea, and possibly a rash. Symptoms usually persist for two to nine days, then disappear, with recurrence after several weeks if the patient remains untreated.	C2890	Bacterial Infection			C90259	Pediatric Terminology		
C	C128430	Early Latent Syphilis	Early Latent Syphilis		Latent syphilis when infection was acquired less than twelve months previously.	Latent syphilis when infection was acquired less than twelve months previously.	C35056	Latent Syphilis			C90259	Pediatric Terminology		
C	C128431	Multidrug-Resistant Mycobacterium tuberculosis	Multidrug-Resistant Mycobacterium tuberculosis		A strain of Mycobacterium tuberculosis that is resistant to isoniazid and rifampin.	A strain of Mycobacterium tuberculosis that is resistant to isoniazid and rifampin.	C14187	Bacteria			C90259	Pediatric Terminology		
C	C128432	Pre-Extensively Drug-Resistant Mycobacterium tuberculosis	Pre-Extensively Drug-Resistant Mycobacterium tuberculosis		A strain of Mycobacterium tuberculosis that is characterized by resistance to isoniazid, rifampin, and one of the following: a) any of the fluoroquinolone antibiotics or b) one or more of three injectable drugs (kanamycin, capreomycin, amikacin).	A strain of Mycobacterium tuberculosis that is characterized by resistance to isoniazid, rifampin, and one of the following: a) any of the fluoroquinolone antibiotics or b) one or more of three injectable drugs (kanamycin, capreomycin, amikacin).	C14187	Bacteria			C90259	Pediatric Terminology		
C	C128433	Extensively Drug-Resistant Mycobacterium tuberculosis	Extensively Drug-Resistant Mycobacterium tuberculosis		A strain of Mycobacterium tuberculosis that is resistant to all of the following: isoniazid, rifampin, any of the fluoroquinolone antibiotics, and at least one of three injectable drugs (kanamycin, capreomycin, amikacin).	A strain of Mycobacterium tuberculosis that is resistant to all of the following: isoniazid, rifampin, any of the fluoroquinolone antibiotics, and at least one of three injectable drugs (kanamycin, capreomycin, amikacin).	C14187	Bacteria			C90259	Pediatric Terminology		
C	C128436	Tonsillopharyngitis	Tonsillopharyngitis		Inflammation of the palatine tonsils and the posterior pharynx (throat).	Inflammation of the palatine tonsils and the posterior pharynx (throat).	C118420	Otolaryngologic Disorder			C90259	Pediatric Terminology		
C	C128438	Variant Creutzfeldt-Jakob Disease	Variant Creutzfeldt-Jakob Disease	vCJD	A form of Creutzfeldt-Jakob disease that is most commonly contracted after consuming meat from an animal suffering from bovine spongiform encephalopathy.	A form of Creutzfeldt-Jakob disease that is most commonly contracted after consuming meat from an animal suffering from bovine spongiform encephalopathy.	C26802	Classic Creutzfeldt-Jakob Disease			C90259	Pediatric Terminology		
C	C128439	Hand Foot and Mouth Disease	Hand, Foot, and Mouth Disease	HFMD	A clinical syndrome that is usually caused by enterovirus infection, and that is characterized by fever, anorexia, and painful sores in the mouth, distal extremities, and/or other sites, including the buttocks.	A clinical syndrome that is usually caused by enterovirus infection, and that is characterized by fever, anorexia, and painful sores in the mouth, distal extremities, and/or other sites, including the buttocks.	C3439	Viral Infection			C90259	Pediatric Terminology		
C	C14198	Disease Vector	Vector	Disease Vector	An invertebrate animal (e.g., tick, mite, mosquito, bloodsucking fly) capable of transmitting an infectious agent among vertebrates.	An organism that can carry and transmit a pathogen to another organism.	C14250	Organism			C90259	Pediatric Terminology		
C	C14209	Fungus	Fungus	Fungi	A kingdom of eukaryotic, heterotrophic organisms that live as saprobes or parasites, including mushrooms, yeasts, smuts, molds, etc. They reproduce either sexually or asexually, and have life cycles that range from simple to complex. Filamentous fungi refer to those that grow as multicellular colonies (mushrooms and molds).	A eukaryotic, heterotrophic organism that lives as a saprobe or parasite, and includes yeasts and molds. It reproduces either sexually or asexually, and has a life cycle that ranges from simple to complex.	C14250	Organism			C90259	Pediatric Terminology		
C	C14286	Yeast	Yeast		Various single-celled members of the fungal families, ascomycetes, basidiomycetes and imperfect fungi that tend to be unicellular for the greater part of their life cycle.	A unicellular fungus that reproduces by mitosis or budding.	C14209	Fungus			C90259	Pediatric Terminology		
C	C14329	Microorganism	Microbe	Microorganism	A microscopic organism. The term microorganism may refer to a prokaryote or eukaryote, and may be a unicellular or multicellular organism. All taxonomic kingdoms contain microorganisms.	A microscopic organism capable of causing disease in humans, plants, or animals. Most microbes are classified into one of four major groups: bacteria, viruses, fungi, or protozoa.	C14250	Organism			C90259	Pediatric Terminology		
C	C14364	Genital Herpes	Genital Herpes		Herpes simplex infection of the genitals, most commonly caused by the herpes simplex-2 virus.	Herpes simplex infection of the genitals, most commonly caused by the herpes simplex-2 virus.	C3439	Viral Infection			C90259	Pediatric Terminology		
C	C17214	Transmission	Transmission		A passage or transfer, as of a disease from one individual to another.	The conveyance of an infection to a person.	C3367	Finding			C90259	Pediatric Terminology		
C	C17449	Antibiotic Resistance	Antibiotic Resistance		The mechanisms, functions, activities, or processes exhibited by microorganisms, especially bacteria, to resist or to become tolerant to antibiotics.	The reduced susceptibility of microorganisms to an anti-infective drug(s).	C3367	Finding			C90259	Pediatric Terminology		
C	C17706	Anergy	Anergy		Diminished immune responsiveness to specific antigens. Induced or programmed clonal lymphocyte anergy is believed to be the second major mechanism (after clonal deletion) of the development of self tolerance by the immune system.	Diminished cellular immune responsiveness to one or more antigens.	C3367	Finding			C90259	Pediatric Terminology		
C	C258	Antibiotic	Antibiotic	Antimicrobial	Substances naturally produced by microorganisms or their derivatives that selectively target microorganisms not humans. Antibiotics kill or inhibit the growth of microorganisms by targeting components of the microbial cell absent from human cells, including bacterial cell walls, cell membrane, and 30S or 50S ribosomal subunits. These substances are used in the treatment of bacterial and other microbial infections.	Substances that kill or inhibit the growth or other functions of microorganisms. These substances are used in the treatment of bacterial and other microbial infections, though this term is most often used to describe antibacterial agents.	C1909	Pharmacologic Substance			C90259	Pediatric Terminology		
C	C26711	Candidiasis	Candidiasis	Candida Infection	Infection with the organism Candida.	An infection that is caused by one of many species of the genus Candida.	C3245	Fungal Infection			C90259	Pediatric Terminology		
C	C26718	Cholangitis	Cholangitis	Biliary Tract Infection	An acute or chronic inflammatory process affecting the biliary tract.	Inflammation of the biliary tract.	C2990	Gastrointestinal Disorder			C90259	Pediatric Terminology		
C	C26745	Dermatophytosis	Dermatophytosis		A common fungal infection of the stratum corneum of the skin, hair, or nails by a dermatophyte. It is characterized by itching, inflammation, redness of the skin, small papular vesicles, central clearing, fissures, scaling, and/or hair loss in the affected area.	A common fungal infection of the stratum corneum of the skin, hair, or nails by a dermatophyte. It is characterized by itching, inflammation, redness of the skin, small papular vesicles, central clearing, fissures, scaling, and/or hair loss in the affected area.	C3245	Fungal Infection			C90259	Pediatric Terminology		
C	C26787	Gonococcal Urethritis	Gonococcal Urethritis	GC Urethritis	Inflammation of the urethra secondary to infection with Neisseria gonorrhoeae; this infection is spread through sexual contact.	Urethritis that is caused by Neisseria gonorrhoeae infection.	C26904	Urethritis			C90259	Pediatric Terminology		
C	C26802	Creutzfeldt-Jakob Disease	Classic Creutzfeldt-Jakob Disease	CJD	A rare transmittable degenerative disorder of the brain caused by prions. Morphologically it is characterized by spongiform degeneration of the cerebral and cerebellar cortex. Signs and symptoms include sleep disturbances, personality changes, aphasia, ataxia, muscle atrophy and weakness, visual loss, and myoclonus. It usually leads to death within a year from the onset of the disease.	A prion disease of humans that is characterized by spongiform degeneration of the cerebral and cerebellar cortex. Three recognized forms are sporadic, familial, and iatrogenic. The iatrogenic form occurs through direct contact with human tissue, a product derived from human tissue, or contaminated medical equipment.	C128346	Prion Disease			C90259	Pediatric Terminology		
C	C26827	Mediastinitis	Mediastinitis		An inflammatory process affecting the mediastinum.	Inflammation of the mediastinum.	C3367	Finding			C90259	Pediatric Terminology		
C	C26866	Prostatitis	Prostatitis		An infectious or non-infectious inflammatory process affecting the prostate gland.	An inflammatory process affecting the prostate gland.	C27019	Male Reproductive System Disorder			C90259	Pediatric Terminology		
C	C26913	Verruca Plantaris	Verruca Plantaris	Plantar Wart	A wart in the plantar surface of the foot. It is caused by human papillomavirus.	A common wart on the plantar surface of the foot.	C5028	Wart			C90259	Pediatric Terminology		
C	C27027	Candida Esophagitis	Esophageal Candidiasis		Esophagitis resulting from Candida.	Candidiasis of the esophagus.	C26711	Candidiasis			C90259	Pediatric Terminology		
C	C27079	Non-Gonococcal Urethritis	Non-Gonococcal Urethritis	NGU	Inflammation of the urethra secondary to infection with any bacteria other than Neisseria gonorrhoeae.	Infectious urethritis that is not caused by Neisseria gonorrhoeae.	C26904	Urethritis			C90259	Pediatric Terminology		
C	C27087	Verruca Vulgaris	Verruca Vulgaris	Common Wart	A wart caused by human papillomavirus. It can appear anywhere on the skin.	A wart on the skin.	C5028	Wart			C90259	Pediatric Terminology		
C	C276	Antiparasitic Agent	Antiparasitic		Any agent that is effective against infections caused by parasitic organisms and is able to inhibit their growth or kill them. This class consists of anthelmintics and antiprotozoals.	Substances that kill or inhibit the growth or other functions of parasites, and that are used in the treatment of parasitic infections.	C1909	Pharmacologic Substance			C90259	Pediatric Terminology		
C	C27864	Parasitic Infection	Parasitic Infection	Parasitic Disease	A successful invasion of a host by an organism that uses the host for food and shelter.	An infection caused by a parasite.	C128320	Infection			C90259	Pediatric Terminology		
C	C281	Antiviral Agent	Antiviral		Any agent that can treat or prevent viral infections by interfering with the viral replication cycle.	Substances that kill or inhibit the growth or other functions of viruses, and that are used in the treatment of viral infections.	C1909	Pharmacologic Substance			C90259	Pediatric Terminology		
C	C28176	Parasite	Parasite	Parasites	Any organism that has a close, symbiotic relationship with a separate, host organism.	An organism that lives on or in a host organism, and that draws its nourishment from that host.	C14250	Organism			C90259	Pediatric Terminology		
C	C28266	Mold	Filamentous Fungus	Mold	A very large group of microscopic fungi that live on plant or animal matter. Most are filamentous organisms and produce spores that can be air-, water-, or insect-borne.	A multicellular fungus that produces filaments and hyphae.	C14209	Fungus			C90259	Pediatric Terminology		
C	C2886	Aspergillosis	Aspergillosis		An infection that is caused by Aspergillus.	A group of diseases which result from an infection with, or allergic response to the fungus Aspergillus.	C26726	Infectious Disorder			C90259	Pediatric Terminology		
C	C2890	Bacterial Infection	Bacterial Infection	Bacterial Disease	An acute infectious disorder that is caused by gram positive or gram negative bacteria; representative examples include pneumococcal, streptococcal, salmonella, and meningeal infections.	An infection caused by a bacterium.	C128320	Infection			C90259	Pediatric Terminology		
C	C29329	Purified Protein Derivative	Purified Protein Derivative	PPD	A purified protein extract derived from the bacterium Mycobacterium tuberculosis. Intradermally-administered, PPD stimulates preprimed CD4 T cells in immunologically competent subjects previously exposed to the bacterium Mycobacterium tuberculosis; these activated CD4 T cells secrete various cytokines that attract granulocytes, monocytes, and macrophages in an inflammatory response known as delayed hypersensitivity. (NCI04)	An extract derived from the supernatant of a culture of Mycobacterium tuberculosis grown under standardized conditions that is used in the tuberculin skin test.	C1909	Pharmacologic Substance			C90259	Pediatric Terminology		
C	C2967	Cryptococcosis	Cryptococcosis		An acute or chronic, localized or disseminated infection by Cryptococcus neoformans.  Sites of involvement include the lungs, central nervous system and meninges, skin, and visceral organs.--2004	An infection that is caused by Cryptococcus neoformans, and in some geographic areas by Cryptococcus gattii, which can be either acute or chronic, and either localized or disseminated; it typically involves the lungs, though disseminated disease can occur.	C3245	Fungal Infection			C90259	Pediatric Terminology		
C	C298	BCG Vaccine	Bacillus Calmette-Guérin Vaccine	BCG Vaccine	A vaccine containing bacillus Calmette-Guerin (BCG), an attenuated strain of Mycobacterium bovis, with non-specific immunoadjuvant and immunotherapeutic activities. Although the mechanism of its anti-tumor activity is unclear, immunization with BCG vaccine likely activates a Th1 cytokine response that includes the induction of interferon. Vaccination with BCG vaccine may be immunoprotective against infection with Mycobacterium tuberculosis.	A tuberculosis vaccine containing bacillus Calmette-Guérin, a live attenuated strain of Mycobacterium bovis. There are many different strains of BCG vaccine, all of which were originally derived from one strain, but which now have very different properties.	C97116	Attenuated Live Vaccine			C90259	Pediatric Terminology		
C	C3245	Fungal Infection	Fungal Infection	Mycosis	An infection caused by a fungus.	An infection caused by a fungus.	C128320	Infection			C90259	Pediatric Terminology		
C	C3289	Opportunistic Infection	Opportunistic Infection	OI	Infection caused by an organism that is capable of causing disease in immunocompromised patients only (e.g. HIV-positive or transplanted patients).--2004	An infection that occurs in an immunocompromised host, but that does not usually cause an infection with similar frequency or severity in a normal (immunocompetent) host.	C26726	Infectious Disorder			C90259	Pediatric Terminology		
C	C3334	Pneumocystis Pneumonia	Pneumocystis Pneumonia	PCP|PJP|Pneumocystis jirovecii Pneumonia	Pneumonia resulting from infection with Pneumocystis jirovecii, frequently seen in the immunologically compromised, such as persons with AIDS, or steroid-treated individuals, the elderly, or premature or debilitated babies during their first three months.  Patients may be only slightly febrile (or even afebrile), but are likely to be extremely weak, dyspneic, and cyanotic. This is a major cause of morbidity among patients with AIDS.	A severe, progressive pneumonia caused by Pneumocystis jirovecii, which is usually seen in immunologically compromised individuals.	C3333	Pneumonia			C90259	Pediatric Terminology		Pneumocystis carinii Pneumonia
C	C3365	Sexually Transmitted Disorder	Sexually Transmitted Infection	STD|STI|Sexually Transmitted Disease|VD	A disorder acquired through sexual contact.	An infection that is acquired through sexual contact.	C26726	Infectious Disorder			C90259	Pediatric Terminology		Venereal Disease
C	C3418	Toxoplasmosis	Toxoplasmosis		A parasitic disease contracted by the ingestion or fetal transmission of toxoplasma gondii.	A protozoan infection that is acquired by the ingestion or maternal-to-fetal transmission of Toxoplasma gondii.	C34953	Protozoal Infection			C90259	Pediatric Terminology		
C	C3439	Viral Infection	Viral Infection	Viral Disease	Any disease caused by a virus.	Any disease caused by a virus.	C128320	Infection			C90259	Pediatric Terminology		
C	C34428	Blastomycosis	Blastomycosis		A fungal infection caused by inhalation of spores of Blastomyces dermatitidis. It presents with flu-like symptoms including fever, chills, cough, pleuritic chest pain and myalgias. It may lead to a chronic granulomatous pulmonary infection and disseminate to other anatomic sites including skin, nervous system and bones.	A fungal infection that is usually caused by inhalation of spores of Blastomyces dermatitidis; it most commonly presents with fever, chills, cough, pleuritic chest pain, and myalgias. The infection can disseminate to other anatomic sites, including skin, nervous system, and bones.	C3245	Fungal Infection			C90259	Pediatric Terminology		
C	C34465	Cholecystitis	Cholecystitis		An acute or chronic inflammation involving the gallbladder wall. It may be associated with the presence of gallstones.	Inflammation of the gallbladder.	C2990	Gastrointestinal Disorder			C90259	Pediatric Terminology		
C	C34528	Dengue Fever	Dengue	Break Bone Fever|Dengue Fever	An acute infection caused by Dengue virus. Signs and symptoms include sudden onset of fever, headache, rash, arthralgia, and myalgia. It is transmitted through mosquitoes.	An infection that is caused by the dengue virus, which is transmitted to humans by mosquitoes, and which is characterized by sudden onset of fever, headache, rash, arthralgia, and myalgia. Occasionally, patients develop either dengue hemorrhagic fever (DHF), a more severe form of the disease that is  characterized by plasma leakage due to increased vascular permeability, or dengue shock syndrome (DSS), which can cause circulatory collapse and possibly death.	C3439	Viral Infection			C90259	Pediatric Terminology		
C	C34702	Hookworm Infection	Hookworm Infection		An infection that is caused by hookworms.	A nematode infection due to Ancylostoma species or Necator americanus. Prevalence and species vary by country. The infection is acquired by larval penetration of the skin, which causes intense pruritus (ground itch), and is followed by a pulmonary migratory phase; adult worms reside in the gastrointestinal tract, where feeding can lead to blood loss, iron deficiency anemia, and sometimes nutritional deficiencies.	C27864	Parasitic Infection			C90259	Pediatric Terminology		
C	C34726	Infectious Mononucleosis	Infectious Mononucleosis	Mono	A condition characterized by an increase in mononuclear white blood cells and swollen lymph nodes, which is usually caused by infection with the Epstein-Barr virus.	A clinical syndrome of fever, sore throat, fatigue, and lymphadenopathy. Epstein-Barr virus is the predominant cause.	C3439	Viral Infection			C90259	Pediatric Terminology		
C	C34784	Loiasis	Loiasis		Infection by the African eye worm, Loa loa.	An infection that is caused by the nematode Loa loa, which is contracted via the bite of a deer fly. In temporary residents of endemic areas, the most common clinical manifestation is Calabar swelling (localized angioedema), typically on the extremities. Infected permanent residents of endemic areas typically manifest eye disease related to wandering of the adult worm. Encephalopathy, cardiomyopathy, and renal disease are related to microfilaraemia.	C27864	Parasitic Infection			C90259	Pediatric Terminology		
C	C34797	Malaria	Malaria		A protozoan infection caused by the genus Plasmodium. There are four species of Plasmodium that can infect humans: Plasmodium falciparum, vivax, ovale, and malariae. It is transmitted to humans by infected mosquitoes. Signs and symptoms include paroxysmal high fever, sweating, chills, and anemia.	Plasmodium parasite infection, characterized by fever, flu-like symptoms, anemia, and jaundice, that may be transmitted through infected mosquito bites, blood transfusion, organ transplant, contaminated needles or syringes, or before or during birth.	C34953	Protozoal Infection			C90259	Pediatric Terminology		
C	C34861	Onchocerciasis	Onchocerciasis	River Blindness	A disease caused by infection with Onchocerca volvulus; symptoms may include pruritis and blindness.	An infection that is caused by the nematode Onchocerca volvulus, which most commonly occurs in tropical climates, and which is transmitted by bites from a black fly. Symptoms include intense pruritus, inflammation, and swelling of skin; if the larvae migrate to the eye, blindness can occur.	C27864	Parasitic Infection			C90259	Pediatric Terminology		
C	C34882	Rheumatic Heart Disease	Rheumatic Heart Disease	RHD	An autoinflammatory condition following an infection with Group A Beta Hemolytic Streptococcus (GABHS), in which the heart is attacked by antibodies formed in reaction to a recent GABHS infection. Chief anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords, all of which can result in valvular dysfunction.	A consequence of acute rheumatic fever that causes chronic cardiac valve damage and/or dysfunction.	C3079	Heart Disorder			C90259	Pediatric Terminology		
C	C34886	Secretory Otitis Media	Otitis Media with Effusion	OME|Secretory Otitis Media|Serous Otitis Media	Otitis media associated with accumulation of fluid in the middle ear.	Otitis media that is associated with the accumulation of fluid in the middle ear without signs or symptoms of an acute infection.	C34885	Otitis Media			C90259	Pediatric Terminology		
C	C34891	Paracoccidioidomycosis	Paracoccidioidomycosis		A systemic fungal infection caused by Paracoccidioides brasiliensis that is most often seen in immunocompromised patients. It affects the mucous membranes, lymph nodes, lungs and bones.	A systemic fungal infection that is caused by Paracoccidioides brasiliensis, which affects the mucous membranes, lymph nodes, lungs and bones, and which is most often seen in immunocompromised patients.	C3245	Fungal Infection			C90259	Pediatric Terminology		
C	C34932	Aspiration Pneumonitis	Aspiration Pneumonitis	Aspiration Pneumonia	Inflammation of the lungs due to the inhalation of solid or liquid material.	Inflammation of the lungs due to the inhalation of solid or liquid material.	C113159	Pneumonitis			C90259	Pediatric Terminology		
C	C34953	Protozoal Infection	Protozoal Infection		An infection that is caused by protozoans.		C27864	Parasitic Infection			C90259	Pediatric Terminology		
C	C35027	Smallpox	Smallpox		A condition that is caused by infection with Variola, and that is characterized by small, raised bumps.	An infection that is caused by one of two viruses: Variola major or Variola minor, both of which are transmitted via inhalation of droplets. A vaccine was developed, and smallpox was declared eradicated by the WHO in 1979.	C3439	Viral Infection			C90259	Pediatric Terminology		
C	C35056	Latent Syphilis	Latent Syphilis		A stage of syphilis characterized by the serologic evidence of infection by Treponema pallidum without evidence of accompanying signs or symptoms related to the disease.	A stage of syphilis that occurs after the secondary stage, and that is characterized by the serologic evidence of infection without the evidence of accompanying signs or symptoms related to the disease.	C35055	Syphilis			C90259	Pediatric Terminology		
C	C35057	Tabes Dorsalis	Tabes Dorsalis		A form of neurosyphilis characterized by slowly progressive degeneration of the spinal cord. Signs and symptoms include pain, ataxia, loss of coordination, personality changes, blindness, urinary incontinence, dementia, and degeneration of the joints.	A form of neurosyphilis that is characterized by slowly progressive degeneration of the spinal cord.	C84935	Neurosyphilis			C90259	Pediatric Terminology		
C	C35131	Vulvovaginitis	Vulvovaginitis		An inflammatory pathologic process that affects the vulva and the vagina.	Inflammation of the vulva and vagina.	C27020	Female Reproductive System Disorder			C90259	Pediatric Terminology		
C	C35151	Chronic Sinusitis	Chronic Sinusitis		Inflammation of the paranasal sinuses that typically lasts beyond eight weeks. It is caused by infections, allergies, and the presence of sinus polyps or deviated septum. Signs and symptoms include headache, nasal discharge, swelling in the face, dizziness, and breathing difficulties.	Sinusitis that lasts more than thirty days without improvement.	C35024	Sinusitis			C90259	Pediatric Terminology		
C	C35483	Bacterial Gastroenteritis	Bacterial Gastroenteritis		Gastroenteritis resulting from a bacterial infection.	Gastroenteritis that is caused by an infection with a bacterial agent.	C2890	Bacterial Infection			C90259	Pediatric Terminology		
C	C35803	Zoonotic Infection	Zoonotic Infection		Infection by an etiologic agent that can be passed between animals and humans.	An infectious agent of an animal that can be transmitted to, and cause disease in, humans. The transference of the infectious agent can be either direct or indirect.	C26726	Infectious Disorder			C90259	Pediatric Terminology		
C	C36170	Viral Hemorrhagic Fever	Viral Hemorrhagic Fever		A group of viral illnesses that are characterized by increased susceptibility to bleeding diatheses.	A disease of viral etiology that is characterized by fever and bleeding, which can progress to high fever, shock and death.	C3439	Viral Infection			C90259	Pediatric Terminology		
C	C3889	Pelvic Inflammatory Disease	Pelvic Inflammatory Disease	PID	Pelvic inflammatory disease (PID) is an acute or chronic inflammation in the pelvic cavity. It is most commonly caused by sexually transmitted diseases, including chlamydia and gonorrhea that have ascended into the uterus, fallopian tubes, or ovaries as a result of intercourse or childbirth, or of surgical procedures, including insertion of IUDs or abortion. PID may be either symptomatic or asymptomatic. It may cause infertility and it may raise the risk of ectopic pregnancy. PID is a disease associated with HIV infection.	A clinical syndrome that is caused by an ascending infection of the female upper genital tract, and that is most commonly caused by sexually transmitted infections.	C26726	Infectious Disorder			C90259	Pediatric Terminology		
C	C4076	Isosporiasis	Cystoisosporiasis		An intestinal infection with Isospora belli.	A protozoan infection that is caused by Cystoisospora belli (formerly known as Isospora belli), which is most commonly acquired from contaminated food or water, and which is characterized by watery diarrhea and abdominal pain.	C34953	Protozoal Infection			C90259	Pediatric Terminology		Isosporiasis
C	C44959	Chlamydophila psittaci Infection	Psittacosis		A bacterial infection caused by Chlamydophila psittaci. Humans are infected by handling sick birds. The Chlamydiae cause respiratory infection manifests with fever, malaise, cough, dyspnea, sore throat, photophobia and headaches.	An infection that is caused by Chlamydophila psittaci, which is transmitted by infected birds; it typically causes a febrile respiratory illness.	C2890	Bacterial Infection			C90259	Pediatric Terminology		
C	C50559	Fasciitis	Fasciitis		Inflammation process in fascia.	Inflammation of the fascia.	C26729	Connective Tissue Disorder			C90259	Pediatric Terminology		
C	C50758	Subclinical Infection	Subclinical Infection	Asymptomatic Infection	Infection associated with no detectable symptoms but caused by microorganisms capable of producing easily recognizable diseases, such a poliomyelitis or mumps.	An infection without associated signs or symptoms.	C128320	Infection			C90259	Pediatric Terminology		
C	C514	Antifungal Agent	Antifungal		Substances that treat systemic or topical infections caused by fungi. Antifungal agents kill or inhibit the growth of fungi, by various mechanisms. These mechanisms include inhibition of fungal mitosis, impairing synthesis or binding to ergosterol, inhibition of RNA or DNA synthesis, and interfering with other fungal metabolic processes.	Substances that kill or inhibit the growth or other functions of fungi and that are used in the treatment of fungal infections.	C1909	Pharmacologic Substance			C90259	Pediatric Terminology		
C	C71079	Herpes Zoster	Zoster	Herpes Zoster|Shingles	A common dermal and neurologic disorder caused by reactivation of the varicella-zoster virus that has remained dormant within dorsal root ganglia, often for decades, after the patient's initial exposure to the virus in the form of varicella (chickenpox). It is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area.	Varicella zoster virus infection that is caused by the reactivation of virus, which can be latent within dorsal root ganglia; zoster is characterized by vesicular lesions clustered unilaterally in a dermatomal distribution of one or more adjacent sensory nerves. Neuralgic pain can occur and can be severe.	C96407	Varicella Zoster Infection			C90259	Pediatric Terminology		
C	C77201	Histoplasmosis	Histoplasmosis		A disease caused by the fungus Histoplasma capsulatum. It primarily affects the lungs but can also occur as a disseminated disease that affects additional organs. The acute respiratory disease has symptoms similar to those of a cold or flu and it usually resolves without treatment in healthy individuals. The disseminated form is generally fatal if untreated.	An often self-limited infection that is caused by Histoplasma capsulatum, which typically manifests as a flu-like illness, but severe disseminated disease can occur.	C3245	Fungal Infection			C90259	Pediatric Terminology		
C	C77212	Zygomycosis	Mucormycosis		Any infection due to a fungus of the Zygomycota phylum. The disease typically involves the rhino-facial-cranial area, lungs, gastrointestinal tract, skin, or less commonly other organ systems. The infecting fungi have a predilection for invading vessels of the arterial system, causing embolization and subsequent necrosis of surrounding tissue.	Any infection due to a fungus of the order Mucorales. The disease typically involves the rhino-facial-cranial area, lungs, gastrointestinal tract, or skin; the infection can also be disseminated.	C3245	Fungal Infection			C90259	Pediatric Terminology		
C	C79702	Paronychia	Paronychia		An acute or chronic infection of the soft tissues around the nail. Symptoms include pain, tenderness, erythema, and swelling around the nail. Acute infection results from minor trauma to the fingertip and Staphylococcus aureus is usually the causative agent. Chronic infection is usually caused by Candida albicans.	An acute (usually bacterial) or chronic (usually fungal) infection of the soft tissue around the nail.	C36281	Integumentary System Finding			C90259	Pediatric Terminology		
C	C80324	Pathogen	Pathogen		An agent of disease; a disease producer.	A microbial agent capable of producing disease.	C14250	Organism			C90259	Pediatric Terminology		
C	C84354	Infectious Otitis Media	Acute Otitis Media	AOM|Infectious Otitis Media|Middle Ear Infection	Inflammation of the anatomical structures of the middle ear secondary to an infectious process. Bacterial etiology is most common, but both viral and fungal pathogens are also possible. Symptoms include erythema and edema of the tympanic membrane, pain, and possibly fever. In severe infections, inflammation and edema of the structures of the middle ear can lead to perforation of the tympanic membrane secondary to the buildup of pressure in the narrow space.	Otitis media that is caused by an infectious agent.	C34885	Otitis Media			C90259	Pediatric Terminology		
C	C84541	African Trypanosomiasis	African Trypanosomiasis		A parasitic disorder caused by protozoa of the Trypanosoma brucei species. It is transmitted by flies and is endemic in various regions of Sub-Saharan Africa. Signs and symptoms include fever, joint pain, headache, and significant swelling of the lymph nodes. If left untreated, the parasitic infection causes anemia, heart, kidney, and endocrine failure, and neurologic damage. Subsequently patients develop confusion, disruption of the sleep cycle, and mental deterioration. The infection may lead to coma and death.	A protozoan infection that is caused by Trypanosoma brucei, which is transmitted by tsetse flies; it is characterized by fever, joint pain, headache, and lymphadenopathy, and it may progress to multi-organ involvement.	C34953	Protozoal Infection			C90259	Pediatric Terminology		Sleeping Sickness
C	C84547	Allergic Bronchopulmonary Aspergillosis	Allergic Bronchopulmonary Aspergillosis	ABPA	An immune reaction to aspergillus in patients usually suffering from asthma or cystic fibrosis.	A hypersensitivity reaction to Aspergillus in patients who are usually suffering from cystic fibrosis or asthma.	C2886	Aspergillosis			C90259	Pediatric Terminology		
C	C84551	Amebiasis	Amebiasis		A parasitic infectious disorder caused by amoebas. The parasite may cause colitis which is manifested with bloody diarrhea, abdominal pain, nausea and fever. In rare cases it may spread to the liver, brain and lungs.	A gastrointestinal parasitic infection that is caused by Entamoeba histolytica, and which has a spectrum of manifestations including bloody diarrhea and colitis; extraintestinal infection involves the liver, brain, and lungs.	C34953	Protozoal Infection			C90259	Pediatric Terminology		
C	C84586	Bartonella Infection	Bartonellosis	Bartonella Infection	A gram-negative bacterial infection caused by Bartonella bacilliformis. It is transmitted by ticks, flies and mosquitoes. Signs and symptoms include fever, headache, muscle pain, enlargement of the lymph nodes and anemia.	An infection that is caused by Bartonella species; it is transmitted by ticks, flies, and mosquitoes.	C2890	Bacterial Infection			C90259	Pediatric Terminology		
C	C84599	Botulism	Botulism		A serious bacterial infection caused by botulinum toxin which is produced by Clostridium botulinum. Patients are infected usually by ingestion of contaminated food or wound contamination. It leads to muscle paralysis which may result in respiratory failure.	A rare but serious paralytic illness that is caused by a nerve toxin that is most often produced by Clostridium botulinum, but also rarely by strains of Clostridium butyricum and Clostridium baratii. There are five types of botulism: foodborne, wound, infant, adult intestinal toxemia (adult intestinal colonization), and iatrogenic.	C2890	Bacterial Infection			C90259	Pediatric Terminology		
C	C84602	Brucellosis	Brucellosis	Undulant Fever	A gram negative bacterial infection caused by bacteria of the genus Brucella. Humans are infected by ingesting unpasteurized milk or meat from infected animals. Signs and symptoms include fevers, sweating, weakness, headache, muscle pain, arthritis and anemia.	An infection that is caused by Brucella species, which is acquired from contact with infected animals, their carcasses, or their milk; it is characterized by fever, sweating, migrating arthralgia, and myalgia.	C2890	Bacterial Infection			C90259	Pediatric Terminology		
C	C84642	Coccidioidomycosis	Coccidioidomycosis	Valley Fever	A fungal infection caused by Coccidioides immitis. Affected individuals usually have mild flu-like symptoms. However, pneumonia and systemic involvement with the formation of abscesses may develop as complications of the disease.	An infection that is caused by Coccidioides immitis, which typically manifests as a flu-like illness, although pneumonia and systemic infection can occur.	C3245	Fungal Infection			C90259	Pediatric Terminology		
C	C84649	Congenital Syphilis	Congenital Syphilis		A life-threatening bacterial infection of the newborn caused by Treponema pallidum. It is transmitted to the infant from a mother with syphilis through the placenta during pregnancy. Signs and symptoms include irritability, fever, failure to thrive, saddle nose, cutaneous rash, and pneumonia.	Treponema pallidum infection in the neonate that was transmitted through the placenta.	C35055	Syphilis			C90259	Pediatric Terminology		
C	C84677	Dracunculiasis	Dracunculiasis	Guinea Worm Disease	A parasitic infection caused by Dracunculus medinensis. It is caused by drinking water contaminated with water fleas. The larvae enter the body through the intestine. Signs and symptoms include pain, edema, blisters, and ulcers.	An infection that is caused by Dracunculus medinensis, which is acquired by drinking water contaminated with infected copepods. The larvae enter the body through the intestine. Signs and symptoms include pain, edema, blisters, and ulcers, with the adult female worm potentially emerging from the skin over time.	C27864	Parasitic Infection			C90259	Pediatric Terminology		
C	C84695	Erythema Infectiosum	Erythema Infectiosum	Fifth Disease	A self-limited viral infectious disorder caused by the human parvovirus B19. It affects predominantly children and is characterized by the development of a bright red skin eruption in the cheeks. It is followed by a maculopapular skin eruption in the extremities which eventually fades into a lacey pattern.	An infection that is caused by parvovirus B19; it is characterized by the development of bright red cheeks ("slapped cheeks"), which is followed by a skin eruption in the extremities that often has a lacy pattern.	C3439	Viral Infection			C90259	Pediatric Terminology		
C	C84891	Microsporidiosis	Microsporidiosis	Microsporidia Infection	A fungal infection caused by Microsporidia. It occurs in immunocompromised patients, causing diarrhea and wasting.	An infection that is caused by a group of spore-forming organisms, which have been re-classified from protozoa to fungi. The infection occurs predominantly in immunocompromised patients; common sites of infection include the cornea, GI tract, and disseminated sites.	C3245	Fungal Infection			C90259	Pediatric Terminology		
C	C85228	Whipple Disease	Whipple Disease		A systemic infection caused by the Gram-positive bacterium Tropheryma whipplei. It affects the small intestine resulting in malabsorption. Other sites or systems affected by the infection are the joints, central nervous system, and the cardiovascular system.	An infection that is caused by the Gram-positive bacterium Tropheryma whipplei, which primarily affects the small intestine resulting in malabsorption.	C2890	Bacterial Infection			C90259	Pediatric Terminology		
C	C85994	Tuberculin Skin Test	Tuberculin Skin Test	TST	A test to determine if a subject has ever had a tuberculosis infection. A small amount of purified tuberculosis protein is placed under the skin of the forearm and a positive skin reaction indicates previous exposure to Mycobacterium tuberculosis.	A test of delayed-type hypersensitivity involving injection into the skin of a small amount of purified protein derivative (PPD). The formation of a specific, defined amount of induration in response to the test suggests the presence of tuberculosis infection.	C25294	Laboratory Procedure			C90259	Pediatric Terminology		
C	C85997	Mantoux Tuberculin Skin Test	Mantoux Tuberculin Skin Test	Mantoux Test	A tuberculin skin test where a standard dose of 5 Tuberculin units of purified protein derivative is injected under the skin of the inner surface of the forearm. Results are read 48-72 hours later.	A tuberculin skin test in which a standard dose of purified protein derivative is injected under the skin of the inner surface of the forearm.	C25294	Laboratory Procedure			C90259	Pediatric Terminology		
C	C94408	Folliculitis	Folliculitis		Inflammation of the hair follicles. Causes include excessive perspiration, skin infections, and skin wounds.	Inflammation of the hair follicles.	C3371	Skin Disorder			C90259	Pediatric Terminology		
C	C94575	Scarlet Fever	Scarlet Fever		A streptococcal infection, mainly occurring among children, that is characterized by a red skin rash, sore throat, and fever.	An erythematous, fine, papular rash  that is associated with Streptococcal pharyngitis.	C2890	Bacterial Infection			C90259	Pediatric Terminology		
C	C99089	Liver Abscess	Liver Abscess	Hepatic Abscess	A bacterial, parasitic, or fungal abscess that develops in the liver. It is usually the result of an abdominal infection, trauma, or surgery in the right upper quadrant. Signs and symptoms include abdominal pain, nausea, vomiting, and fever.	An abscess within the liver.	C26686	Abscess			C90259	Pediatric Terminology