A C125492 First Trimester Antepartum Hemorrhage First Trimester Antepartum Hemorrhage Excessive blood loss within the first trimester but prior to onset of labor. C114371 Antepartum Hemorrhage C90259 Pediatric Terminology A C125493 Second Trimester Antepartum Hemorrhage Second Trimester Antepartum Hemorrhage Excessive blood loss within the second trimester but prior to onset of labor. C114371 Antepartum Hemorrhage C90259 Pediatric Terminology A C125494 Third Trimester Antepartum Hemorrhage Third Trimester Antepartum Hemorrhage Excessive blood loss within the third trimester but prior to onset of labor. C114371 Antepartum Hemorrhage C90259 Pediatric Terminology C C27153 Lupus Erythematosus Lupus Erythematosus Lupus An autoimmune, connective tissue chronic inflammatory disorder affecting the skin, joints, kidneys, lungs, heart, and the peripheral blood cells. It is more commonly seen in women than men. Variants include discoid and systemic lupus erythematosus. An umbrella term referring to disease entities such as cutaneous, subacute cutaneous, discoid and systemic lupus erythematosus. C2889 Autoimmune Disease C90259 Pediatric Terminology C C27179 Juvenile Rheumatoid Arthritis Juvenile Rheumatoid Arthritis (AQ) An older, deprecated term that encompassed three major types of autoimmune or autoinflammatory arthritis in children: systemic-onset, pauciarticular, or polyarticular arthritis. The juvenile rheumatoid arthritis classification system has been replaced by the International League of Associations for Rheumatology (ILAR) juvenile idiopathic arthritis classification system. An older, deprecated term that encompassed three major types of autoimmune or autoinflammatory arthritis in children: systemic-onset, pauciarticular, or polyarticular arthritis. The juvenile rheumatoid arthritis classification system has been replaced by the International League of Associations for Rheumatology (ILAR) juvenile idiopathic arthritis classification system. C2889 Autoimmune Disease C90259 Pediatric Terminology JRA C C27191 Hashimoto Thyroiditis Hashimoto's Disease Chronic Lymphocytic Thyroiditis|Hashimoto's Thyroiditis An autoimmune disorder caused by the production of autoantibodies against thyroid tissue. There is progressive destruction of the thyroid follicles leading to hypothyroidism. An autoimmune disorder characterized by inflammation and lymphocytic infiltration of the thyroid gland, sometimes associated with reduced thyroid function. C3009 Endocrine System Disorder C90259 Pediatric Terminology C C27204 Rheumatologic Disorder Rheumatic Disease Collagen Vascular Disease|Rheumatologic Disorder Inflammatory and degenerative diseases of connective tissue structures, such as arthritis. An umbrella term used to encompass disorders characterized by autoimmunity, autoinflammatory processes, joint or connective tissue inflammation or degeneration. C2889 Autoimmune Disease C90259 Pediatric Terminology Connective Tissue Disease|Inflammatory Rheumatism C C34412 Bartter Syndrome Bartter Syndrome A rare inherited syndrome characterized by juxtaglomerular cell hyperplasia, hyperaldosteronism, hypokalemia, and alkalosis. Patients have high levels of plasma renin concentration which is not associated with hypertension. A rare, inherited syndrome characterized by juxtaglomerular cell hyperplasia, hyperaldosteronism, hypokalemia, and alkalosis. Affected individuals have high concentration of plasma renin that is not associated with hypertension. C28193 Syndrome C90259 Pediatric Terminology C C34416 Behcet Syndrome Behcet Syndrome Behcet Disease|Behcet's Syndrome|Behçet Disease|Behçet's Syndrome A rare chronic inflammatory disorder of unknown etiology. It is characterized by the development of ulcers in the mouth and genital region and uveitis. Other signs and symptoms include arthritis, deep vein thrombosis and superficial thrombophlebitis. A systemic vasculitis affecting both arteries and veins which manifests primarily as recurrent oral and genital ulceration, uveitis, characteristic rash, and arthritis. It may also cause central nervous system disease, gastrointestinal inflammation or ulceration, or thrombophlebitis. C26912 Vasculitis C90259 Pediatric Terminology Behçet-Adamantiades Syndrome|Morbus Behçet's Syndrome|Silk Road Disease C C34639 Angle Closure Glaucoma Closed Angle Glaucoma Angle Closure Glaucoma The sudden increase of intraocular pressure, resulting in pain and an abrupt decrease in visual acuity. Optic nerve damage secondary to appositional closure of the angle of the eye. C26782 Glaucoma C90259 Pediatric Terminology C C34643 IgA Nephropathy IgA Nephropathy A chronic autoimmune glomerulonephritis characterized by the deposition of immunoglobulin A in the mesangium of the glomeruli. It is manifested with hematuria and mild proteinuria. Glomerulonephropathy characterized by mesangial deposition of IgA antibody in the glomerulus. It is often characterized by hematuria, which may include episodes of visible hematuria during acute illness, and/or proteinuria. C26784 Glomerulonephritis C90259 Pediatric Terminology Berger's Disease C C34837 Nasopharyngitis Nasopharyngitis An inflammatory process that affects the nasopharynx. Inflammation of the nasopharynx. C118420 Otolaryngologic Disorder C90259 Pediatric Terminology C C34844 Minimal Change Glomerulonephritis Minimal Change Disease Minimal Change Nephropathy A glomerular disorder characterized by the electron microscopic finding of loss of podocyte foot processes. Light microscopic examination does not show glomerular changes. Patients present with proteinuria and nephrotic syndrome. Nephrotic syndrome that demonstrates little histologic evidence of pathology by light microscopy; ultra-structural change is evident under electron microscopy, demonstrating diffuse effacement and fusion of podocyte processes. C26784 Glomerulonephritis C90259 Pediatric Terminology Lipoid Nephrosis|Nil Disease C C50717 Purulent Discharge Purulent Discharge Pus-containing fluid that is draining from an orifice or wound. Pus-containing fluid that is draining from an orifice or wound. C100104 Sign or Symptom C90259 Pediatric Terminology C C50724 Raynaud Phenomenon Raynaud Phenomenon Raynaud's Phenomenon An episodic vasoconstriction resulting in discoloration of the skin and pain in the affected areas, often involving fingers or toes. Classically associated with triphasic color changes (white, blue, red) but may be biphasic. Often occurs in response to cold temperatures or emotional stress. May be primary or secondary to an underlying autoimmune disease. An episodic vasoconstriction resulting in discoloration of the skin and pain in the affected areas, often involving fingers or toes. Classically associated with triphasic color changes (white, blue, red) but may be biphasic. Often occurs in response to cold temperatures or emotional stress. May be primary or secondary to an underlying autoimmune disease. C35117 Vascular Disorder C90259 Pediatric Terminology Raynaud Disease|Raynaud's Disease C C61272 Glycogen Storage Disease Glycogen Storage Disease An inherited metabolic disorder characterized either by defects in glycogen synthesis or defects in the breaking down of glycogen. It results either in the creation of abnormal forms of glycogen or accumulation of glycogen in the tissues. C34816 Congenital Metabolic Disorder C90259 Pediatric Terminology C C61274 Fucosidosis Fucosidosis An autosomal recessive lysosomal storage disease characterized by a defective alpha-L-fucosidase. It results in accumulation of fucose in the tissues. Signs and symptoms include psychomotor retardation, dysostosis multiplex, and neural disturbances. C3101 Genetic Disorder C61250 Lysosomal Storage Disorder C90259 Pediatric Terminology C C61275 Mannosidosis Mannosidosis A rare autosomal recessive lysosomal storage disease characterized by a deficient activity of the enzymes alpha-D-mannosidase or beta-mannosidase. Clincal signs and symptoms include hepatomegaly, splenomegaly, hearing loss, mental retardation, skeletal abnormalities, and recurrent respiratory infections. C3101 Genetic Disorder C61250 Lysosomal Storage Disorder C90259 Pediatric Terminology C C61277 Psoriatic Arthritis Psoriatic Arthritis Arthritis Psoriatica Joint inflammation associated with psoriasis. An inflammatory arthritis typically associated with dactylitis, nail dystrophy, and the absence of rheumatoid factor in an individual with psoriasis or a family history of psoriasis. C2883 Arthritis C90259 Pediatric Terminology Psoriatic Arthropathy C C61278 Still Disease Systemic Juvenile Rheumatoid Arthritis (AQ) An inflammatory disorder most often affecting children. It is characterized by the presence of arthritis, salmon-colored rash, spiking fevers, fatigue, and sore throats. An older, deprecated term for a category of juvenile rheumatoid arthritis that manifests with arthritis as well as systemic signs and symptoms, including high fevers, rash, hepatosplenomegaly, lymphadenopathy and anemia. C27179 Juvenile Rheumatoid Arthritis (AQ) C90259 Pediatric Terminology Still's Disease|Systemic JRA|Systemic Onset Juvenile Rheumatoid Arthritis|sJRA C C61279 Oligoarticular Still Disease Pauciarticular Juvenile Rheumatoid Arthritis (AQ) Juvenile rheumatoid arthritis affecting four or fewer joints, usually asymmetrically. The most commonly affected joints are the knee, elbow, wrist, and ankle. An older, deprecated term for a category of juvenile rheumatoid arthritis that affects fewer than five joints; it most commonly affects the large joints, and is most often asymmetric. C27179 Juvenile Rheumatoid Arthritis (AQ) C90259 Pediatric Terminology Oligoarticular JRA|Oligoarticular Juvenile Rheumatoid Arthritis|Pauciarticular JRA C C61280 Polyarticular Still Disease Polyarticular Juvenile Rheumatoid Arthritis (AQ) Juvenile rheumatoid arthritis affecting multiple joints, usually symmetrically. It may be associated with low grade fever, anemia, and weight loss. Patients usually test negative for rheumatoid factor. An older, deprecated term for a category of juvenile rheumatoid arthritis that affects five or more joints. A subset of patients are rheumatoid factor positive. C27179 Juvenile Rheumatoid Arthritis (AQ) C90259 Pediatric Terminology Polyarticular JRA C C6985 Invasive Hydatidiform Mole Invasive Hydatidiform Mole A complete hydatidiform mole or very rarely a partial mole that invades the myometrium. A complete hydatidiform mole or very rarely a partial mole that invades the myometrium. C3110 Hydatidiform Mole C9305 Cancer C90259 Pediatric Terminology C C70549 Microscopic Polyarteritis Microscopic Polyangiitis MPA A systemic necrotizing vasculitis that typically affects the small and medium-sized muscular arteries. In some cases, however, microscopic vessels are also affected (e.g., in the kidneys), a condition that has been called microscopic polyarteritis or polyangiitis; this disorder is felt to be more closely associated with Wegener granulomatosis than to classic polyarteritis nodosa. Systemic vasculitis affecting small vessels that is necrotizing and non-granulomatous, with little to no immune complex deposition. Clinically it is characterized by involvement of the kidneys, skin, lung, and peripheral nerves. Antineutrophil cytoplasmic antibody (anti-myeloperoxidase (anti-MPO)) is positive in most cases. C26912 Vasculitis C90259 Pediatric Terminology Microscopic Polyarteritis C C85021 Preeclampsia Preeclampsia A systolic blood pressure of 140 mmHg or higher, or a diastolic blood pressure of 90 mmHg or higher on two occasions at least 4 hours apart (or greater than or equal to 160/110 mmHg within a short interval) after 20 weeks of gestation in a woman with previously normal blood pressure. It may present with proteinuria but if not, it may be associated with thrombocytopenia, impaired liver function, progressive renal insufficiency, pulmonary edema, or new-onset cerebral or visual disturbances. A systolic blood pressure of 140 mmHg or higher, or a diastolic blood pressure of 90 mmHg or higher on two occasions at least 4 hours apart (or greater than or equal to 160/110 mmHg within a short interval) after 20 weeks of gestation in a woman with previously normal blood pressure. It may present with proteinuria but if not, it may be associated with thrombocytopenia, impaired liver function, progressive renal insufficiency, pulmonary edema, or new-onset cerebral or visual disturbances. C4371 Gestational Hypertension C90259 Pediatric Terminology C C85033 Prune Belly Syndrome Prune Belly Syndrome Syndrome of Agenesis of Abdominal Muscles|Triad Syndrome A rare congenital syndrome occurring almost exclusively in males. It is characterized by partial or complete lack of the abdominal wall muscles, enlarged bladder, dilated ureters, hydronephrosis, and undescended testes. A congenital syndrome, occurring almost exclusively in males, characterized by partial or complete absence of the abdominal wall muscles, enlarged bladder, dilated ureters, hydronephrosis, and undescended testes, with or without renal insufficiency. C3101 Genetic Disorder C90259 Pediatric Terminology Eagle-Barrett Syndrome C C85034 Pseudohypoaldosteronism Pseudohypoaldosteronism An inherited or acquired disorder of electrolyte metabolism, characterized by the inability of the renal tubules to respond to aldosterone. It is manifested by hyperkalemic metabolic acidosis, urinary salt wasting, normal or increased aldosterone secretion and normal glomerular filtration rate. C3009 Endocrine System Disorder C90259 Pediatric Terminology C C85042 Complex Regional Pain Syndrome I Complex Regional Pain Syndrome I A neurologic condition characterized by burning pain, tenderness, swelling, and changes in the skin color and temperature of a body part or extremity that has no identifiable nerve injury; most pediatric patients present with this form. A neurologic condition characterized by burning pain, tenderness, swelling, and changes in the skin color and temperature of a body part or extremity that has no identifiable nerve injury; most pediatric patients present with this form. C119048 Pain Amplification Syndrome C90259 Pediatric Terminology Reflex Neurovascular Dystrophy|Reflex Sympathetic Dystrophy Syndrome C C92261 Hemoglobin C Measurement Measurement of Hemoglobin C The determination of the amount of hemoglobin C present in a sample. C64848 Hemoglobin Measurement C90259 Pediatric Terminology C C92561 Developmental Coordination Disorder Developmental Dyspraxia Development Coordination Disorder|Developmental Coordination Disorder A disorder characterized by an impairment in the development of an individual's motor coordination skills; this impairment in motor development is not due to a medical condition. A developmental disorder characterized by voluntary motor skill impairment. C89338 Neurodevelopmental Disorder C90259 Pediatric Terminology Clumsy Child Syndrome C C114869 Arrest of Labor in Second Stage Arrest of Labor in Second Stage Prolonged Second Stage of Labor|Second Stage Arrest At least 2 hours of pushing in multiparous women and at least 3 hours of pushing in nulliparous women. Longer durations may be appropriate on an individualized basis (e.g., with the use of epidural analgesia or with fetal malposition) as long as progress is being documented. At least 2 hours of pushing in multiparous women and at least 3 hours of pushing in nulliparous women. Longer durations may be appropriate on an individualized basis (e.g., with the use of epidural analgesia or with fetal malposition) as long as progress is being documented). C118419 Labor Complication C90259 Pediatric Terminology C C27146 Hemophilia A Hemophilia A Factor VIII Deficiency|Hereditary Factor VIII Deficiency Disease An inherited deficiency of coagulation factor VIII characterized by the tendency to spontaneous or exaggerated post-traumatic hemorrhage. Inherited as an X-linked recessive disease, hemophilia A is the most common hemophilia, occurring in approximately 1 in 10,000 male births. C3093 Hemophilia C90259 Pediatric Terminology