A C115335 Proximal Urethra The part of the urethra that is closer to the bladder. The part of the urethra that is close to the bladder. (CDISC) C32221 Body Part C90259 Pediatric Terminology A C122161 Ward's Triangle A radiolucent and fracture-prone triangular zone in the proximal femur. An area of low density in the femoral neck, as seen by radiography, which is bounded by the principle compressive, secondary compressive and primary tensile trabeculae. (CDISC) C32221 Body Part C90259 Pediatric Terminology A C122710 Medical Device Failure Medical Device Failure A medical device that is no longer functioning. A medical device that is no longer functioning. C78254 Device Complication C90259 Pediatric Terminology A C122711 Medical Device Malfunction Medical Device Malfunction A medical device that is functioning incorrectly. A medical device that is functioning incorrectly. C78254 Device Complication C90259 Pediatric Terminology A C122712 Medical Device Dislodged Medical Device Dislodged A medical device that was placed properly, but which has moved from the intended location. A medical device that was placed properly, but which has moved from the intended location. C78254 Device Complication C90259 Pediatric Terminology A C122713 Medical Device Misplaced Medical Device Misplaced A medical device that was placed in an unintended location. A medical device that was placed in an unintended location. C78254 Device Complication C90259 Pediatric Terminology A C122721 Hypercarbia Hypercarbia Excessive concentration of carbon dioxide in the blood. Excessive concentration of carbon dioxide in the blood. C36292 Laboratory Test Result C90259 Pediatric Terminology A C122722 Accidental Drug Ingestion Accidental Medicine Ingestion The unintentional consumption of a drug. The unintentional consumption of a drug. C3367 Finding C90259 Pediatric Terminology A C122784 Tracheobronchitis Tracheobronchitis Inflammation of the tracheobronchial tree. Inflammation of the tracheobronchial tree. C26871 Respiratory System Disorder C90259 Pediatric Terminology A C122785 Pneumatosis Pneumatosis The presence of gas in an anatomical location where it is not normally found. The presence of gas in an anatomical location where it is not normally found. C100104 Signs or Symptoms C90259 Pediatric Terminology A C122786 Incarcerated Inguinal Hernia Incarcerated Inguinal hernia The trapping of bowel or omentum inside the inguinal canal that cannot be reduced, resulting in inflammation, pain, nausea, and possible bowel obstruction. The trapping of bowel or omentum inside the inguinal canal that cannot be reduced, resulting in inflammation, pain, nausea, and possible bowel obstruction. C34690 Inguinal Hernia C90259 Pediatric Terminology A C122818 Closure Patent Ductus Arteriosus Closure Patent Ductus Arteriosus The closing of the ductus arteriosus; this can occur naturally or as a result of a therapeutic procedure. The closing of the ductus arteriosus; this can occur naturally or as a result of a therapeutic procedure. C35552 Cardiovascular Finding C90259 Pediatric Terminology A C122821 Elevated Alkaline Phosphatase Elevated Alkaline Phosphatase An elevated concentration of alkaline phosphatase in the blood. An elevated concentration of alkaline phosphatase in the blood. C36292 Laboratory Test Result C90259 Pediatric Terminology A C122822 Cholelithiasis Cholelithiasis The presence of calculi in the gallbladder. The presence of calculi in the gallbladder. C2990 Gastrointestinal Disorder C90259 Pediatric Terminology A C33735 Tarsal Joint The synovial joints between the tarsal bones of the foot. A joint formed by the union of tarsal bones. (CDISC) C32221 Body Part C90259 Pediatric Terminology C C121589 Central Line Complication Central Line Complication A problem with a central venous access catheter or site of insertion. A problem with a central venous access catheter or site of insertion. C62996 C90259 Pediatric Terminology C C122445 Feeding Tube Complication Feeding Tube Complication Any problem with a feeding tube or its site of insertion. Any problem with a feeding tube or its site of insertion. C62996 C90259 Pediatric Terminology C C122527 Disrupted Suture Disrupted Suture The loss of tension or continuity of sutures. The loss of tension or continuity of sutures. C62950 C90259 Pediatric Terminology C C121604 Catheter-Related Inflammation Catheter-Related Inflammation Inflammation associated with the use of a catheter. Inflammation associated with the use of a catheter. C62996 C90259 Pediatric Terminology C C122439 Dislodged Catheter Dislodged Catheter A catheter that has moved from its intended location. A catheter that has moved from its intended location. C62950 C90259 Pediatric Terminology C C113303 Adipose Tissue Deposition Adipose Tissue Deposition The deposition of lipids in tissue. The deposition of lipids in tissue. C100104 Signs or Symptoms C90259 Pediatric Terminology C C115149 Adenovirus Infection Adenovirus Infection An infectious process caused by adenovirus. The virus may cause respiratory illness, conjunctivitis, gastroenteritis, and cystitis. An infectious process caused by adenovirus. The virus may cause respiratory illness, conjunctivitis, gastroenteritis, and cystitis. C3439 Viral Infection C90259 Pediatric Terminology C C121556 Back Arching Back Arching A convex curvature of the spine that occurs when an individual thrusts forward the shoulders and pulls back the abdomen. A convex curvature of the spine that occurs when an individual thrusts forward the shoulders and pulls back the abdomen. C100104 Signs or Symptoms C90259 Pediatric Terminology C C121557 Bloody Discharge Bloody Discharge The leaking of serosanguinous fluids from an orifice or wound. The leaking of serosanguinous fluids from an orifice or wound. C100104 Signs or Symptoms C90259 Pediatric Terminology C C121558 Breath Holding Breath Holding Episodic apnea, which is more common in young children and usually resolves by age six. Episodic apnea, which is more common in young children and usually resolves by age six. C100104 Signs or Symptoms C90259 Pediatric Terminology C C121560 Cat Bite Cat Bite A wound received from the teeth of a cat. A wound received from the teeth of a cat. C3671 Injury C90259 Pediatric Terminology C C121562 Cystic Fibrosis Pulmonary Exacerbation Cystic Fibrosis Pulmonary Exacerbation An acute episode of worsening pulmonary symptoms related to cystic fibrosis. An acute episode of worsening pulmonary symptoms related to cystic fibrosis. C26871 Respiratory System Disorder C90259 Pediatric Terminology C C121574 Hypophagia Hypophagia Reduced ingestion of food. Reduced ingestion of food. C100104 Signs or Symptoms C90259 Pediatric Terminology C C121577 Pulmonary Function Test Decreased Pulmonary Function Test Decreased A decrease in any of the parameters used to measure the mechanical function of the lungs and upper airway. A decrease in any of the parameters used to measure the mechanical function of the lungs and upper airway. C36292 Laboratory Test Result C90259 Pediatric Terminology C C121607 Central Line Infection Central Line Infection An infectious process related to a central venous catheter. An infectious process related to a central venous catheter. C26726 Infectious Disorder C90259 Pediatric Terminology C C121623 Aphagia Aphagia The inability or refusal to swallow. The inability or refusal to swallow. C100104 Signs or Symptoms C90259 Pediatric Terminology C C121624 Agonal Respiration Agonal Respiration An abnormal breathing pattern originating from lower brainstem neurons and characterized by labored breaths, gasping, and, often, myoclonus and grunting. An abnormal breathing pattern originating from lower brainstem neurons and characterized by labored breaths, gasping, and, often, myoclonus and grunting. C100104 Signs or Symptoms C90259 Pediatric Terminology C C121626 Airway Compromise Airway Compromise The inhibition of normal respiration by physical obstruction(s) to the airway. The inhibition of normal respiration by physical obstruction(s) to the airway. C100104 Signs or Symptoms C90259 Pediatric Terminology C C121628 Altered Mental Status Altered Mental Status A change to an individual's judgment, orientation (to place, time, and self), intellectual functioning, or mood from their baseline. A change to an individual's judgment, orientation (to place, time, and self), intellectual functioning, or mood from their baseline. C3858 Mental and Behavioral Signs and Symptoms C90259 Pediatric Terminology C C121669 Disordered Eating Disordered Eating Abnormal eating behaviors, including binge eating, compulsive eating, emotional eating, night eating, and self-induced vomiting, though not at a level that rises to the diagnosis of eating disorder. Abnormal eating behaviors, including binge eating, compulsive eating, emotional eating, night eating, and self-induced vomiting, though not at a level that rises to the diagnosis of eating disorder. C35470 Behavioral Disorder C90259 Pediatric Terminology C C122408 Pulmonary Nodules Pulmonary Nodules Multiple, small, round or oval, benign or malignant growths in the lung(s), which can be due to infectious, inflammatory, or neoplastic processes. Multiple, small, round or oval, benign or malignant growths in the lung(s), which can be due to infectious, inflammatory, or neoplastic processes. C26871 Respiratory System Disorder C90259 Pediatric Terminology C C122411 Scleral Icterus Scleral Icterus Yellowing of the white part of the eyes, often due to a rise in bilirubin levels. Yellowing of the white part of the eyes, often due to a rise in bilirubin levels. C26767 Eye Disorder C90259 Pediatric Terminology C C122414 Autoimmune Encephalitis Autoimmune Encephalitis Inflammation of the brain secondary to an immune response triggered by the body itself. Inflammation of the brain secondary to an immune response triggered by the body itself. C2934 Central Nervous System Disorder C90259 Pediatric Terminology C C122416 Refusal to Bear Weight Refusal to Bear Weight A reluctance to place any body weight on a limb, which is most commonly secondary to pain or discomfort. A reluctance to place any body weight on a limb, which is most commonly secondary to pain or discomfort. C100104 Signs or Symptoms C90259 Pediatric Terminology C C122419 Dog Bite Dog Bite A wound received from the teeth of a dog. A wound received from the teeth of a dog. C3671 Injury C90259 Pediatric Terminology C C122425 Port Site Infection Port Site Infection An infection at an anatomic location used for vascular access. An infection at an anatomic location used for vascular access. C26726 Infectious Disorder C90259 Pediatric Terminology C C122426 Acquired Cytomegaloviral Infection Acquired Cytomegaloviral Infection An infection with the Cytomegalovirus that is not present from birth. An infection with the Cytomegalovirus that is not present from birth. C3439 Viral Infection C90259 Pediatric Terminology C C122427 Congenital Cytomegaloviral Infection Congenital Cytomegaloviral Infection An infection with the Cytomegalovirus that is present from birth. An infection with the Cytomegalovirus that is present from birth. C96411 Childhood Viral Disease C90259 Pediatric Terminology C C122435 Impaired Balance Impaired Balance A deficit in equilibrium, which may manifest as unsteady ambulation or inability to maintain an upright position. A deficit in equilibrium, which may manifest as unsteady ambulation or inability to maintain an upright position. C100104 Signs or Symptoms C90259 Pediatric Terminology C C122437 Positive Blood Culture Positive Blood Culture A laboratory test result demonstrating the presence of a specific organism in a blood sample after culture. A laboratory test result demonstrating the presence of a specific organism in a blood sample after culture. C36292 Laboratory Test Result C90259 Pediatric Terminology C C122438 Blood Urea Nitrogen Increased Blood Urea Nitrogen Increased Laboratory results demonstrating an increase in the concentration of urea nitrogen in a blood sample. Laboratory results demonstrating an increase in the concentration of urea nitrogen in a blood sample. C36292 Laboratory Test Result C90259 Pediatric Terminology C C122443 Coombs Test Positive Coombs Test Positive A laboratory test result demonstrating the presence of antibodies that act against red blood cells. A laboratory test result demonstrating the presence of antibodies that act against red blood cells. C36292 Laboratory Test Result C90259 Pediatric Terminology C C122470 Fistula Discharge Fistula Discharge The leakage of a substance from a fistula. The leakage of a substance from a fistula. C100104 Signs or Symptoms C90259 Pediatric Terminology C C122478 Gait Unsteady Gait Unsteady A shaky or wobbly manner of walking. A shaky or wobbly manner of walking. C100104 Signs or Symptoms C90259 Pediatric Terminology C C122507 Hemoglobin A1c Increased Hemoglobin A1c Increased A laboratory test result demonstrating an increase in the glycosylated hemoglobin in a blood sample. A laboratory test result demonstrating an increase in the glycosylated hemoglobin in a blood sample. C36292 Laboratory Test Result C90259 Pediatric Terminology C C122528 Violent Behavior Violent Behavior Any action that results in intimidation, harm, damage, or destruction of someone or something. Any action that results in intimidation, harm, damage, or destruction of someone or something. C3858 Mental and Behavioral Signs and Symptoms C90259 Pediatric Terminology C C122529 Unresponsive to Stimuli Unresponsive to Stimuli An individual whose level of consciouness is such that he is not responsive to any stimulus. An individual whose level of consciousness is such that he is not responsive to any stimulus. C100104 Signs or Symptoms C90259 Pediatric Terminology C C122573 Screaming Screaming A loud, vociferous cry or yell; it can be the result of many emotions, including pain, excitement, or fear. A loud, vociferous cry or yell; it can be the result of many emotions, including pain, excitement, or fear. C100104 Signs or Symptoms C90259 Pediatric Terminology C C122575 Positive Herpes Simplex Virus Culture Positive Herpes Simplex Virus Culture Laboratory test results demonstrating the presence of the Herpes Simplex virus in a specimen. Laboratory test results demonstrating the presence of the Herpes Simplex virus in a specimen. C36292 Laboratory Test Result C90259 Pediatric Terminology C C122576 Staphylococcus Aureus Infection Staphylococcus Aureus Infection An infectious process in which the bacteria Staphylococcus aureus is present. An infectious process in which the bacteria Staphylococcus aureus is present. C2890 Bacterial Disease C90259 Pediatric Terminology C C122579 Phonophobia Phonophobia A fear of sounds, which can include fear of voices, including one's own voice, in addition to other sounds. A fear of sounds, which can include fear of voices, including one's own voice, in addition to other sounds. C100104 Signs or Symptoms C90259 Pediatric Terminology C C122582 Positive Pseudomonas Culture Positive Pseudomonas Culture A laboratory test result demonstrating the presence of bacteria from the genus Pseudomonas in a sample after culture. A laboratory test result demonstrating the presence of bacteria from the genus Pseudomonas in a sample after culture. C36292 Laboratory Test Result C90259 Pediatric Terminology C C122587 Indwelling Urinary Catheter Indwelling Urinary Catheter A hollow tube that is inserted and left in the bladder to promote the drainage of urine. A hollow tube that is inserted and left in the bladder to promote the drainage of urine. C62103 Device C90259 Pediatric Terminology C C122639 Duodenostomy Site Duodenostomy Site A surgically created external opening into the duodenum. A surgically created external opening into the duodenum. C122645 Enterostomy Site C90259 Pediatric Terminology C C122640 Colostomy Site Colostomy Site A surgically created external opening into the colon. A surgically created external opening into the colon. C122645 Enterostomy Site C90259 Pediatric Terminology C C122641 Cystostomy Site Cystostomy Site A surgically created external opening into the anterior wall of the bladder. A surgically created external opening into the anterior wall of the bladder. C122638 Ostomy Sites C90259 Pediatric Terminology C C122642 Ileostomy Site Ileostomy Site A surgically created external opening into the ileum. A surgically created external opening into the ileum. C122645 Enterostomy Site C90259 Pediatric Terminology C C122643 Tracheostomy Site Tracheostomy Site A surgically created external opening into the trachea. A surgically created external opening into the trachea. C122638 Ostomy Sites C90259 Pediatric Terminology C C122644 Urostomy Site Urostomy Site A surgically created external opening into the urinary tract. A surgically created external opening into the urinary tract. C122638 Ostomy Sites C90259 Pediatric Terminology C C122645 Enterostomy Site Enterostomy Site A surgically created external opening into the intestine. A surgically created external opening into the intestine. C122638 Ostomy Sites C90259 Pediatric Terminology C C122646 Gastrostomy Site Gastrostomy Site A surgically created external opening into the stomach. A surgically created external opening into the stomach. C122638 Ostomy Sites C90259 Pediatric Terminology C C122647 Jejunostomy Site Jejunostomy Site A surgically created external opening into the jejunum. A surgically created external opening into the jejunum. C122645 Enterostomy Site C90259 Pediatric Terminology C C122648 Nephrostomy Site Nephrostomy Site A surgically created external opening into the renal pelvis. A surgically created external opening into the renal pelvis. C122638 Ostomy Sites C90259 Pediatric Terminology C C25534 Induration Induration The quality of being hard, the process of hardening, or an abnormally hard spot or place, particularly of the skin. The quality of being hard, the process of hardening, or an abnormally hard spot or place, particularly of the skin. C100104 Signs or Symptoms C90259 Pediatric Terminology C C26737 Cyanosis Cyanosis A bluish or purplish discoloration of the skin and mucous membranes resulting from a reduced concentration of oxygenated hemoglobin in the blood. A bluish or purplish discoloration of the skin and mucous membranes resulting from a reduced concentration of oxygenated hemoglobin in the blood. C100104 Signs or Symptoms C90259 Pediatric Terminology C C26796 Hydronephrosis Hydronephrosis The collection of urine in the renal pelvis that results in dilatation of the renal pelvis and calyces, which can be caused by obstruction of urine flow or vesicoureteral reflux. Signs and symptoms include flank pain, nausea, vomiting, fever, and dysuria. The collection of urine in the renal pelvis that results in dilatation of the renal pelvis and calyces, which can be caused by obstruction of urine flow or vesicoureteral reflux. Signs and symptoms include flank pain, nausea, vomiting, fever, and dysuria. C3149 Kidney Disease C90259 Pediatric Terminology C C26901 Erythema Erythema Red discoloration of the skin caused by infectious agents, inflammation, drug hypersensitivity, or underlying disease. Red discoloration of the skin caused by infectious agents, inflammation, drug hypersensitivity, or underlying disease. C100104 Signs or Symptoms C90259 Pediatric Terminology C C2885 Ascites Ascites The accumulation of fluid in the peritoneal cavity, which may be serous, hemorrhagic, or the result of tumor metastasis to the peritoneum. The accumulation of fluid in the peritoneal cavity, which may be serous, hemorrhagic, or the result of tumor metastasis to the peritoneum. C100104 Signs or Symptoms C90259 Pediatric Terminology C C2975 Cystic Fibrosis Cystic Fibrosis A congenital, autosomal, metabolic disorder affecting the exocrine glands. The secretions of exocrine glands are abnormal, resulting in excessively viscid mucus production that causes obstruction of passageways, including pancreatic and bile ducts, intestines, and bronchi. Symptoms usually appear in childhood, and include meconium ileus, poor growth despite good appetite, malabsorption and foul bulky stools, chronic bronchitis with cough, recurrent pneumonia, bronchiectasis, emphysema, clubbing of the fingers, and salt depletion in hot weather secondary to increased sodium and chloride concentration in sweat. A congenital, autosomal, metabolic disorder affecting the exocrine glands. The secretions of exocrine glands are abnormal, resulting in excessively viscid mucus production that causes obstruction of passageways, including pancreatic and bile ducts, intestines, and bronchi. Symptoms usually appear in childhood, and include meconium ileus, poor growth despite good appetite, malabsorption and foul bulky stools, chronic bronchitis with cough, recurrent pneumonia, bronchiectasis, emphysema, clubbing of the fingers, and salt depletion in hot weather secondary to increased sodium and chloride concentration in sweat. C34816 Congenital Metabolic Disorder C90259 Pediatric Terminology C C3003 Effusion Effusion A collection of fluid in a body cavity, which may be the result of a non-neoplastic disorder (e.g. heart failure) or a tumor (e.g. carcinoma of the lung). A collection of fluid in a body cavity, which may be the result of a non-neoplastic disorder (e.g. heart failure) or a tumor (e.g. carcinoma of the lung). C100104 Signs or Symptoms C90259 Pediatric Terminology C C3063 Graft Versus Host Disease Graft Versus Host Disease A reaction, which may be fatal, in an immunocompromised subject (host) who has received an antigenically incompatible tissue transplant (graft) from an immunocompetent donor. The reaction is secondary to the activation of the transplanted cells against those host tissues that express an antigen not expressed by the donor, and is seen most commonly following bone marrow transplantation; acute disease is seen after 5-40 days, and chronic disease occurs weeks to months after transplantation. A reaction, which may be fatal, in an immunocompromised subject (host) who has received an antigenically incompatible tissue transplant (graft) from an immunocompetent donor. The reaction is secondary to the activation of the transplanted cells against those host tissues that express an antigen not expressed by the donor, and is seen most commonly following bone marrow transplantation; acute disease is seen after 5-40 days, and chronic disease occurs weeks to months after transplantation. C3507 Immune System Disorder C90259 Pediatric Terminology C C3354 Respiratory Syncytial Virus Infection Respiratory Syncytial Virus Infection Infection with the respiratory syncytial virus, an RNA virus of the genus Pneumovirus, in the family Paramyxoviridae, which is characterized by the formation of syncytia in tissue culture. It causes minor respiratory infection with rhinitis and cough in adults, but is capable of causing severe bronchitis and bronchopneumonia in young children. Infection with the respiratory syncytial virus, an RNA virus of the genus Pneumovirus, in the family Paramyxoviridae, which is characterized by the formation of syncytia in tissue culture. It causes minor respiratory infection with rhinitis and cough in adults, but is capable of causing severe bronchitis and bronchopneumonia in young children. C3439 Viral Infection C90259 Pediatric Terminology C C3376 Sleep Disorder Sleep Disorder A change from the patient's baseline sleeping pattern, in the hours slept and/or an alteration/dysfunction in the stages of sleep. A change from the patient's baseline sleeping pattern, in the hours slept and/or an alteration/dysfunction in the stages of sleep. C26835 Neurologic Disorder C90259 Pediatric Terminology C C34571 Interstitial Emphysema Interstitial Emphysema Pathologic accumulation of air in the interstitium of the lungs, which is caused by the rupture of alveoli and terminal bronchioles, and is most often seen in premature infants that need mechanical ventilation for respiratory distress syndrome. Pathologic accumulation of air in the interstitium of the lungs, which is caused by the rupture of alveoli and terminal bronchioles, and is most often seen in premature infants that need mechanical ventilation for respiratory distress syndrome. C3198 Lung Disorder C90259 Pediatric Terminology C C34630 Gagging Gagging The sudden, coordinated, involuntary contraction of pharyngeal muscles in an attempt to prevent any matter from passing into the posterior pharynx; it is stimulated by touching the posterior palate, tongue, or pharynx, or by psychic stimuli. The sudden, coordinated, involuntary contraction of pharyngeal muscles in an attempt to prevent any matter from passing into the posterior pharynx; it is stimulated by touching the posterior palate, tongue, or pharynx, or by psychic stimuli. C100104 Signs or Symptoms C90259 Pediatric Terminology C C34832 Myoclonic Jerk Myoclonic Jerk A sudden, involuntary contraction of a muscle or group of muscles; these movements may develop as a symptom of a number of neurological diseases, including epilepsy, Parkinson's disease, Alzheimer's disease, or Creutzfeldt-Jacob disease. A sudden, involuntary contraction of a muscle or group of muscles; these movements may develop as a symptom of a number of neurological diseases, including epilepsy, Parkinson's disease, Alzheimer's disease, or Creutzfeldt-Jacob disease. C100104 Signs or Symptoms C90259 Pediatric Terminology C C34857 Numbness Numbness A loss of the sensation of feeling in an area of the body. A loss of the sensation of feeling in an area of the body. C100104 Signs or Symptoms C90259 Pediatric Terminology C C34938 Postoperative Hemorrhage Postoperative Hemorrhage Bleeding occurring after completion of a surgical procedure, which may occur immediately or may be delayed, and which may or may not be wound related. Bleeding occurring after completion of a surgical procedure, which may occur immediately or may be delayed, and which may or may not be wound related. C2959 Complication C90259 Pediatric Terminology C C35082 Traumatic Subcutaneous Emphysema Traumatic Subcutaneous Emphysema The infiltration of air into the skin tissue secondary to traumatic tissue disruption. The infiltration of air into the skin tissue secondary to traumatic tissue disruption. C3671 Injury C90259 Pediatric Terminology C C35268 Macrocephaly Macrocephaly An abnormal increase in head circumference, which can have a variety of causes, including hydrocephalus, enlarged brain, and cranial hyperostosis. An abnormal increase in head circumference, which can have a variety of causes, including hydrocephalus, enlarged brain, and cranial hyperostosis. C2934 Central Nervous System Disorder C90259 Pediatric Terminology C C4376 Renal Failure Renal Failure An acute or chronic disorder characterized by the inability of the kidneys to adequately filter the blood substances, resulting in uremia and electrolyte imbalances. Acute renal failure is usually associated with oliguria or anuria, hyperkalemia, and pulmonary edema. Chronic renal failure is irreversible. Either form can require hemodialysis. An acute or chronic disorder, characterized by the inability of the kidneys to adequately filter the blood substances, resulting in uremia and electrolyte imbalances. Acute renal failure is usually associated with oliguria or anuria, hyperkalemia, and pulmonary edema. Chronic renal failure is irreversible. Either form can require hemodialysis. C3149 Kidney Disease C90259 Pediatric Terminology C C50437 Body Substance Discharge Body Substance Discharge The leakage of a substance from an orifice or wound. The leakage of a substance from an orifice or wound. C100104 Signs or Symptoms C90259 Pediatric Terminology C C50446 Laceration Laceration A cut or tear in any tissue. A cut or tear in any tissue. C3671 Injury C90259 Pediatric Terminology C C50458 Ambulation Difficulty Ambulation Difficulty Any persistent problem with walking. Any persistent problem with walking. C100104 Signs or Symptoms C90259 Pediatric Terminology C C50494 Choking Choking Interference with respiration by compression or obstruction of the larynx or trachea. Interference with respiration by compression or obstruction of the larynx or trachea. C100104 Signs or Symptoms C90259 Pediatric Terminology C C50618 Intraocular Pressure Rise Intraocular Pressure Rise Increased pressure of the intraocular fluid in the eye. Increased pressure of the intraocular fluid in the eye. C26767 Eye Disorder C90259 Pediatric Terminology C C50635 Loss of Consciousness Loss of Consciousness An inability to purposefully respond to stimuli. An inability to purposefully respond to stimuli. C100104 Signs or Symptoms C90259 Pediatric Terminology C C50717 Purulent Discharge Purulent Discharge Pus-containing fluid that is draining from an orifice or wound. Pus-containing fluid that is draining from an orifice or wound. C100104 Signs or Symptoms C90259 Pediatric Terminology C C54355 Increased Drug Level Increased Drug Level A laboratory test result demonstrating an increased concentration of a specific drug. A laboratory test result demonstrating an increased concentration of a specific drug. C36292 Laboratory Test Result C90259 Pediatric Terminology C C78249 Increased Creatinine Increased Creatinine A laboratory test result demonstrating an increased concentration of creatinine in a biological specimen. A laboratory test result demonstrating an increased concentration of creatinine in a biological specimen. C36292 Laboratory Test Result C90259 Pediatric Terminology C C78254 Device Complication Device Complication Any problem arising from the use of a medical device. Any problem arising from the use of a medical device. C2959 Complication C90259 Pediatric Terminology C C78366 INR Increased INR Increased A laboratory test result demonstrating an increased ratio of the patient's prothrombin time to a control sample. A laboratory test result demonstrating an increased ratio of the patient's prothrombin time to a control sample. C36292 Laboratory Test Result C90259 Pediatric Terminology C C80085 Hemoglobin Decreased Hemoglobin Decreased A laboratory test result demonstrating decreased levels of hemoglobin in a biological specimen. A laboratory test result demonstrating decreased levels of hemoglobin in a biological specimen. C36292 Laboratory Test Result C90259 Pediatric Terminology C C80522 Urine Output Decreased Urine Output Decreased A finding indicating that the urine production is less than 500 milliliters during a 24 hour period. A finding indicating that the urine production is less than 500 milliliters during a 24 hour period. C100104 Signs or Symptoms C90259 Pediatric Terminology C C85022 Priapism Priapism Persistent and usually painful erection that lasts for at least four hours in the absence of physical or psychological stimulation, which can be caused by hematologic disorders, including sickle cell disease and leukemia, spinal cord injuries, and medications. Persistent and usually painful erection that lasts for at least four hours, in the absence of physical or psychological stimulation, which can be caused by hematologic disorders, including sickle cell disease and leukemia, spinal cord injuries, and medications. C100104 Signs or Symptoms C90259 Pediatric Terminology C C87087 Intercostal Retractions Intercostal Retractions The marked inward movement of the muscles between the ribs during inhalation, indicating that there is reduced pressure in the thoracic cavity, and which can be a sign of breathing difficulties. The marked inward movement of the muscles between the ribs during inhalation, indicating that there is reduced pressure in the thoracic cavity, and which can be a sign of breathing difficulties. C100104 Signs or Symptoms C90259 Pediatric Terminology C C90501 Labored Breathing Labored Breathing Breathing that requires observed effort or an increased amount of energy. Breathing that requires observed effort or an increased amount of energy. C100104 Signs or Symptoms C90259 Pediatric Terminology C C96218 Skin Eschar Skin Eschar A crust that covers necrotic tissue in the skin that is caused by a burn or gangrene. A crust that covers necrotic tissue in the skin that is caused by a burn or gangrene. C100104 Signs or Symptoms C90259 Pediatric Terminology C C98950 Hyperammonemia Hyperammonemia A laboratory test result demonstrating an increased concentration of ammonia in the blood. A laboratory test result demonstrating an increased concentration of ammonia in the blood. C27120 Electrolyte Disorder C90259 Pediatric Terminology C C99059 Short Bowel Syndrome Short Bowel Syndrome Malabsorption that results from the removal of a large segment of the small intestine or, less frequently, from the complete dysfunction of a large portion of the small intestine. Signs and symptoms include diarrhea, steatorrhea, and weigh loss. Malabsorption that results from the removal of a large segment of the small intestine or, less frequently, from the complete dysfunction of a large portion of the small intestine. Signs and symptoms include diarrhea, steatorrhea, and weigh loss. C97171 Congenital Abnormality of the Digestive System C90259 Pediatric Terminology C C101034 Intentional Trauma Intentional Trauma An injury that is not the result of an accident or natural causes. An injury that is not the result of an accident or natural causes. C3671 Injury C90259 Pediatric Terminology C C111908 Angiotensin Converting Enzyme Inhibitor Fetopathy Angiotensin Converting Enzyme Inhibitor Fetopathy Fetal embryopathy associated with maternal angiotensis converting enzyme (ACE) inhibitor use during pregnancy that may include fetal acute renal failure, growth restriction, oligohydramnios, calvaria abnormalities, preterm birth, and pulmonary hypoplasia with respiratory distress. Fetal embryopathy associated with maternal ACE inhibitor use that may include growth restriction, oligohydramnios, calvaria abnormalities, preterm birth, pulmonary hypoplasia and acute kidney injury. C92719 Fetal Disorder C90259 Pediatric Terminology C C111910 Fetal Virilization Fetal Virilization Inappropriate secondary sex characteristics in the neonate usually due to in utero androgen exposure. The development of male secondary sexual characteristics in a biologically female fetus that is most often due to in utero exposure to androgens. C92711 Fetal Finding C79859 Virilization C90259 Pediatric Terminology C C111944 Histologic Chorioamnionitis Histologic Chorioamnionitis Inflammation of the fetal sac membranes that is characterized by neutrophilic infiltration of the amnion and chorion. A maternal neutrophilic response resulting in migration of neutrophils from the decidua into the chorion and amnion of the extraplacental membranes and the chorionic plate. C26720 Chorioamnionitis C90259 Pediatric Terminology C C112858 Early Pregnancy Loss Early Pregnancy Loss Pregnancy loss before 10th week of gestation with documentation of a confirmed pregnancy. Pregnancy loss before 10th week of gestation. C90491 Pregnancy Outcome C90259 Pediatric Terminology C C113768 Direct Hyperbilirubinemia Direct Hyperbilirubinemia Abnormally high level of conjugated bilirubin in the blood. Abnormally high level of conjugated bilirubin in the blood. C27088 Hyperbilirubinemia C90259 Pediatric Terminology C C113785 Indirect Hyperbilirubinemia Indirect Hyperbilirubinemia Abnormally high level of unconjugated bilirubin in the blood. Abnormally high level of unconjugated bilirubin in the blood. C27088 Hyperbilirubinemia C90259 Pediatric Terminology C C114281 Parotitis Parotitis Inflammation of the parotid glands. Inflammation of the parotid glands. C118420 Otolaryngologic Disorder C90259 Pediatric Terminology C C115248 Methicillin-Resistant Staphylococcus Aureus Infection Methicillin-Resistant Staphylococcus Aureus Infection A bacterial infection that is caused by Staphylococcus aureus and is resistant to methicillin treatment. A bacterial infection that is caused by Staphylococcus aureus and is resistant to methicillin treatment. C2890 Bacterial Disease C90259 Pediatric Terminology C C116364 Auditory Neuropathy Spectrum Disorder Auditory Neuropathy Spectrum Disorder A hearing disorder characterized by impaired transmission of signals through the auditory nerve, resulting in mild to severe hearing loss and poor speech perception. A group of hearing disorders characterized by impaired transmission of signal through the auditory nerve with abnormal or absent auditory brainstem response with hearing loss and poor speech perception. C63711 Sensory Disorder C90259 Pediatric Terminology C C118316 Mucosal Ulcer Mucosal Ulcer A circumscribed loss of integrity of the mucous membrane. A circumscribed loss of integrity of the mucous membrane. C3426 Ulcer C90259 Pediatric Terminology C C121582 Drooling Drooling Saliva spilling out of the mouth. Saliva spilling from the mouth. C100104 Signs or Symptoms C90259 Pediatric Terminology C C121588 Foreign Body Ingestion Foreign Body Ingestion The swallowing of an item not intended for consumption. The swallowing of an item not intended for consumption. C3671 Injury C90259 Pediatric Terminology C C121616 Wound Discharge Wound Discharge The material exuded from a wound, either surgical or traumatic. The material exuded from a wound, either surgical or traumatic. C100104 Signs or Symptoms C90259 Pediatric Terminology C C121627 Altered Level of Consciousness Altered Level of Consciousness A level of awareness and arousal other than normal. A level of awareness and arousal other than normal. C100104 Signs or Symptoms C90259 Pediatric Terminology C C121629 Disturbance of Temperature Regulation Disturbance of Temperature Regulation Any condition characterized by an inability to regulate body temperature. Any condition characterized by an inability to regulate body temperature. C100104 Signs or Symptoms C90259 Pediatric Terminology C C121630 Increased Respiratory Secretion Increased Respiratory Secretion An increase in respiratory secretions. An increase in respiratory secretions. C100104 Signs or Symptoms C90259 Pediatric Terminology C C121661 Intrusive Thought Intrusive Thought An unwelcome and persistent idea, image or thought that is upsetting to an individual. An unwelcome and persistent idea, image, or thought that is upsetting to an individual. C100104 Signs or Symptoms C90259 Pediatric Terminology C C122409 Ostomy Site Pain Ostomy Site Pain Pain at the site of an ostomy. Pain at the site of an ostomy. C3303 Pain C90259 Pediatric Terminology C C122410 Absence of Bowel Movement Absence of Bowel Movement The lack of any bowel movements. The lack of any bowel movements. C100104 Signs or Symptoms C90259 Pediatric Terminology C C122412 Vaso-Occlusive Crisis Vaso-Occlusive Crisis An exacerbation of sickle cell disease. An exacerbation of sickle cell disease. C35117 Vascular Disorder C90259 Pediatric Terminology C C122413 Ulcerative Colitis Flare Ulcerative Colitis Flare An exacerbation of ulcerative colitis. An exacerbation of ulcerative colitis. C2990 Gastrointestinal Disorder C90259 Pediatric Terminology C C122430 Abnormal Behavior Abnormal Behavior Conduct that is unusual for the individual. Conduct that is unusual for the individual. C3858 Mental and Behavioral Signs and Symptoms C90259 Pediatric Terminology C C122444 Decreased Physical Activity Decreased Physical Activity A reduction in the normal physical activity for an individual. A reduction in the normal physical activity for an individual. C100104 Signs or Symptoms C90259 Pediatric Terminology C C122512 Ketonuria Ketonuria The presence of ketone bodies in the urine. The presence of ketone bodies in the urine. C36292 Laboratory Test Result C90259 Pediatric Terminology C C122513 Hyperlactemia Hyperlactemia Abnormally high level of lactate in the blood. Abnormally high concentration of lactate in the blood. C36292 Laboratory Test Result C90259 Pediatric Terminology C C122516 Abnormal Liver Function Test Abnormal Liver Function Test Atypical results found on serum liver enzyme testing, which may indicate significant disease and/or disease progression. Atypical results found on serum liver enzyme testing, which may indicate significant disease and/or disease progression. C36292 Laboratory Test Result C90259 Pediatric Terminology C C122523 Methicillin-Resistant Staphylococcus Aureus Pneumonia Methicillin-Resistant Staphylococcus Aureus Pneumonia Pneumonia that is caused by Staphylococcus aureus and is resistant to methicillin treatment. Pneumonia that is caused by Staphylococcus aureus and is resistant to methicillin treatment. C2890 Bacterial Disease C90259 Pediatric Terminology C C122526 Mycoplasmal Pneumonia Mycoplasmal Pneumonia Pneumonia caused by Mycoplasma pneumoniae. Signs and symptoms include productive cough, fever, chills, shortness of breath, and chest pain. Pneumonia caused by Mycoplasma pneumoniae. Signs and symptoms include productive cough, fever, chills, shortness of breath, and chest pain. C2890 Bacterial Disease C90259 Pediatric Terminology C C122572 Rhinovirus Infection Rhinovirus Infection An infectious process caused by rhinovirus. The virus usually causes upper respiratory infections, but can infect the lower tract as well. An infectious process caused by rhinovirus. The virus usually causes upper respiratory infections, but can infect the lower tract as well. C3439 Viral Infection C90259 Pediatric Terminology C C122574 Lupus Flare Lupus Flare An exacerbation of the chronic disease lupus. An exacerbation of the chronic disease lupus. C3507 Immune System Disorder C90259 Pediatric Terminology C C122577 Status Asthmaticus Status Asthmaticus An acute exacerbation of asthma, characterized by inadequate response to initial bronchodilators. An acute exacerbation of asthma, characterized by an inadequate response to the initial use of bronchodilators and the progressive worsening of bronchial obstruction and shortness of breath, which can result in the need for mechanical ventilation and/or possibly death. C26871 Respiratory System Disorder C90259 Pediatric Terminology C C122578 Throat Tightening Throat Tightening The sensation of constriction or contraction in the throat area. The sensation of constriction or contraction in the throat area. C100104 Signs or Symptoms C90259 Pediatric Terminology C C122580 Pneumatosis Intestinalis Pneumatosis Intestinalis The presence of gas within the wall of the large or small intestine. The presence of gas within the wall of the large or small intestine. C2990 Gastrointestinal Disorder C90259 Pediatric Terminology C C122581 Postoperative Infection Postoperative Infection Any infection documented following a surgical procedure that was not evident or suspected prior to the procedure. An infection documented following a surgical procedure that was not present or incubating prior to the procedure. C26726 Infectious Disorder C90259 Pediatric Terminology C C122583 Hemiparesis Hemiparesis Weakness or incomplete paralysis of either the left or right side of the body. Weakness or incomplete paralysis of either the left or right side of the body. C4731 Neuropathy C90259 Pediatric Terminology C C26726 Infectious Disorder Infectious Disorder A disorder resulting from the presence and activity of a microbial, viral, fungal, or parasitic agent. It can be transmitted by direct or indirect contact. A disorder resulting from the presence and activity of a microbial, viral, fungal, or parasitic agent. It can be transmitted by direct or indirect contact. C2991 Disease or Disorder C90259 Pediatric Terminology C C26739 Sensorineural Hearing Loss Sensorineural Hearing Loss Hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem. Hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem. C35731 Hearing Loss C90259 Pediatric Terminology C C26860 Pleuritis Pleuritis Inflammation of the pleura. It is usually caused by infections. Chest pain while breathing or coughing is the presenting symptom. Inflammation of the pleura. C26871 Respiratory System Disorder C90259 Pediatric Terminology C C26909 Uveitis Uveitis An inflammatory process affecting a part of or the entire uvea. Causes include inflammatory agents (e.g., herpes simplex, herpes zoster, leptospirosis) and systemic diseases (e.g., inflammatory bowel disease, multiple sclerosis, systemic lupus erythematosus, ankylosing spondylitis). Patients present with pain and redness in the eye, light sensitivity, and blurred and decreased vision. Inflammation of the iris, ciliary body, and/or choroid (uveal tract). C26767 Eye Disorder C90259 Pediatric Terminology C C27071 Transient Hypogammaglobulinemia of Infancy Transient Hypogammaglobulinemia of Infancy A rare, primary humoral immunodeficiency of childhood characterized by decreasing serum levels of immunoglobulin G (IgG) as maternal antibodies clear the circulation while serum levels of immunoglobulin A and immunoglobulin M remain normal or are slightly decreased. Diagnosis may be suspected after the age of six months when a child's own synthesis of IgG should accelerate but it must be confirmed retrospectively after normalization of all serum immunoglobulin levels is seen by ages 2-6. This disorder may be caused by inadequate activation of progenitor B cells, defective class-switching or may even represent a maturational variant. Typically, a normal response to protein antigens is found while there is a notably diminished response to viral and bacterial polysaccharide antigens. Clinical presentation may include recurrent infections especially those of the respiratory tract. Despite increased susceptibility to infection in childhood, this disorder is self-limited with minimal implications for a normal life span. Transitory decrease in the concentration of IgG below established reference ranges, in an infant or child less than 6 months of age. IgA and IgM concentrations may be decreased as well. C3507 Immune System Disorder C90259 Pediatric Terminology C C28137 Oral Candidiasis Oral Candidiasis Infection of the mucosal lining of the mouth with the fungus Candida albicans. Infection of the mucosal lining of the mouth with the fungus Candida albicans. C26726 Infectious Disorder C90259 Pediatric Terminology C C28397 Asthma Asthma A chronic respiratory disease manifested as difficulty breathing due to the narrowing of bronchial passageways. A chronic respiratory disease caused by obstruction of the bronchi and small airways, and characterized by wheezing and shortness of breath. C26871 Respiratory System Disorder C90259 Pediatric Terminology C C2881 Arrhythmia Cardiac Arrhythmia Any variation from the normal rate or rhythm (which may include the origin of the impulse and/or its subsequent propagation) in the heart. Any variation from the normal rate or rhythm (which may include the origin of the impulse and/or its subsequent propagation) in the heart. C78245 Cardiac Conduction Disorder C90259 Pediatric Terminology C C30085 Muscle Contraction Muscle Contraction The process where thick (myosin) and thin (actin) filaments slide against each other to produce a shortening or tensing of the muscle cell or fiber. The process where thick (myosin) and thin (actin) filaments slide against each other to produce a shortening or tensing of the muscle cell or fiber. C100104 Signs or Symptoms C90259 Pediatric Terminology C C3090 Hematuria Hematuria Blood in the urine. The presence of red blood cells in the urine. C3149 Kidney Disease C90259 Pediatric Terminology C C3094 Hemoptysis Hemoptysis Coughing up blood from the respiratory tract. Coughing up blood from the respiratory tract. C26871 Respiratory System Disorder C90259 Pediatric Terminology C C3285 Ocular Hypertension Ocular Hypertension Abnormally high intraocular pressure. Abnormally high intraocular pressure. C26767 Eye Disorder C90259 Pediatric Terminology C C3439 Viral Infection Viral Infection Any disease caused by a virus. Any disease caused by a virus. C26726 Infectious Disorder C90259 Pediatric Terminology C C34399 Arteritis Arteritis An inflammatory process affecting an artery. Inflammation of an artery. C35117 Vascular Disorder C90259 Pediatric Terminology C C34460 Cerebral Palsy Cerebral Palsy A group of disorders affecting the development of movement and posture, often accompanied by disturbances of sensation, perception, cognition, and behavior. It results from damage to the fetal or infant brain. A non-progressive, neurological syndrome presenting in infancy or early childhood that is caused by brain injury or malformation and is characterized by permanent impairment of muscle coordination and various movement disorders. C26835 Neurologic Disorder C89328 Pediatric Disease or Disorder C90259 Pediatric Terminology C C34596 Internal Strabismus Internal Strabismus A form of strabismus in which one or both eyes are deviated medially. A form of strabismus in which one or both eyes are deviated medially. C100104 Signs or Symptoms C90259 Pediatric Terminology C C3472 Severe Combined Immunodeficiency Severe Combined Immunodeficiency X-linked or autosomal recessive disorder characterized by defects of both humoral and cell mediated immunity, resulting in low or absent antibody levels, leukopenia, marked susceptibility to infections, and early death.--2004 X-linked or autosomal recessive disorder characterized by defects of both humoral and cell mediated immunity, resulting in low or absent antibody levels, leukopenia, marked susceptibility to infections, and early death.--2004 C3507 Immune System Disorder C90259 Pediatric Terminology C C34808 Mass Mass A benign or malignant pathologic structure in any part of the body, resulting from a neoplastic accumulation of cells, inflammatory cells, or cystic changes. A benign or malignant pathologic structure in any part of the body, resulting from a neoplastic accumulation of cells, inflammation, or cystic changes. C3262 Neoplasm C90259 Pediatric Terminology C C34831 Myocarditis Myocarditis Inflammation of the muscle tissue of the heart. Inflammation of the myocardium. C3079 Heart Disease C90259 Pediatric Terminology C C34982 Retinopathy of Prematurity Retinopathy of Prematurity A bilateral retinopathy characterized by neovascularization, scarring, retinal detachment, and eventually blindness. It may be mild or severe. It occurs in babies born prematurely. Causes include oxygen toxicity and hypoxia. A retinal condition of very immature infants that may be characterized by non-vascularized retina that may lead to neovascularization, scarring, retinal detachment, and blindness. C98996 Neonatal Disorder C62601 Retinopathy C90259 Pediatric Terminology C C35043 Stutter Stutter A speech disorder characterized by frequent sound or syllable repetitions, sound prolongations, or other dysfluencies that are inappropriate for the individual's age. A speech disorder characterized by frequent sound or syllable repetitions, sound prolongations, or other dysfluencies that are inappropriate for the individual's age. C100104 Signs or Symptoms C90259 Pediatric Terminology C C35109 Anterior Uveitis Anterior Uveitis Inflammation of the iris and anterior chamber of the eye. Inflammation of the anterior uveal tract. C26909 Uveitis C90259 Pediatric Terminology C C35111 Posterior Uveitis Posterior Uveitis An inflammatory process that affects the choroid. Inflammation of the posterior uveal tract. C26909 Uveitis C90259 Pediatric Terminology C C35199 Otorrhea Otorrhea Discharge or drainage of fluid from the ear. Discharge or drainage of fluid from the ear. C100104 Signs or Symptoms C90259 Pediatric Terminology C C35294 Hepatic Mass Hepatic Mass A space-occupying pathologic process that affects the liver parenchyma. A space-occupying pathologic process that affects the liver parenchyma. C3262 Neoplasm C90259 Pediatric Terminology C C35295 Mediastinal Mass Mediastinal Mass A mass present in the mediastinal space. A mass present in the mediastinal space. C3262 Neoplasm C90259 Pediatric Terminology C C35448 Eye Discharge Eye Discharge Liquid exudate from the eye. Liquid exudate from the eye. C100104 Signs or Symptoms C90259 Pediatric Terminology C C35651 Post-Procedural Pain Post-Procedural Pain Pain experienced after a medical intervention through the time expected for associated acute effects to abate. Pain experienced after a medical intervention through the time expected for associated acute effects to abate. C3303 Pain C90259 Pediatric Terminology C C39594 Skin Rash Skin Rash Any change in the skin which affects its appearance or texture. A rash may be localized to one part of the body, or affect all the skin. Rashes may cause the skin to change color, itch, become warm, bumpy, dry, cracked or blistered, swell and may be painful. An eruption in the skin which affects its appearance and/or texture. C36281 Integumentary System Finding C100104 Signs or Symptoms C90259 Pediatric Terminology C C49343 Deep Vein Thrombosis Deep Venous Thrombosis A blood clot in a deep vein, predominantly in the lower extremity, but may include the pelvis or upper extremity. Formation of a blood clot within a deep vein. C99107 Venous Thrombosis C90259 Pediatric Terminology C C50487 Cerebrospinal Fluid Leakage Cerebrospinal Fluid Leakage The loss of cerebrospinal fluid into the surrounding tissues. The loss of cerebrospinal fluid into the surrounding tissues. C100104 Signs or Symptoms C90259 Pediatric Terminology C C50563 Fetal Distress Fetal Distress Signs or symptoms which may be indicative of distress to a fetus, which may include repetitive variable decelerations, fetal tachycardia or bradycardia, late decelerations, or low biophysical profile. Signs or symptoms which may be indicative of distress to a fetus, which may include repetitive variable decelerations, fetal tachycardia or bradycardia, late decelerations, or low biophysical profile. C81236 Birth Complication C92711 Fetal Finding C90259 Pediatric Terminology C C50640 Low Blood Oxygen Saturation Low Blood Oxygen Saturation A low level of the degree to which oxygen is bound to hemoglobin given as a percentage calculated by dividing the maximum oxygen capacity into the actual oxygen content and multiplying by 100. Oxygen saturation usually is measured using pulse oximetry. A decrease in the concentration of oxyhemoglobin as contrasted to the concentration deoxyhemoglobin in the blood. C100104 Signs or Symptoms C90259 Pediatric Terminology C C50704 Postoperative Wound Infection Postoperative Wound Infection Infection of a surgical skin incision. Infection of a surgical skin incision. C26726 Infectious Disorder C90259 Pediatric Terminology C C50795 Vaginal Discharge Vaginal Discharge Normal or abnormal secretions from the vagina. Mucus produced by the cervical glands is discharged from the vagina naturally, especially during the childbearing years. Causes of abnormal vaginal discharge include infectious agents (e.g., Neisseria gonorrhea, Chlamydia trachomatis, Trichomonas, and Candida albicans), the presence of foreign bodies, and cervical or vaginal cancer. Normal or abnormal secretions from the vagina. Mucus produced by the cervical glands is discharged from the vagina naturally, especially during the childbearing years. Causes of abnormal vaginal discharge include infectious agents (e.g., Neisseria gonorrhea, Chlamydia trachomatis, Trichomonas, and Candida albicans), the presence of foreign bodies, and cervical or vaginal cancer. C100104 Signs or Symptoms C90259 Pediatric Terminology C C53482 Influenza Influenza An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system. An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system. C3439 Viral Infection C90259 Pediatric Terminology C C54282 Rhinorrhea Rhinorrhea A discharge of fluid from the nose. A discharge of fluid from the nose. C100104 Signs or Symptoms C90259 Pediatric Terminology C C77963 Crying Crying The shedding of tears associated with emotions, usually sadness but also joy or frustration. The shedding of tears associated with emotions, usually sadness, but also joy or frustration. C100104 Signs or Symptoms C90259 Pediatric Terminology C C78253 Depressed Level Of Consciousness Depressed Level Of Consciousness A neurologic state characterized by decreased ability to perceive and respond. A neurologic state characterized by decreased ability to perceive and respond. C100104 Signs or Symptoms C90259 Pediatric Terminology C C78639 Tooth Infection Tooth Infection An infectious process affecting a tooth. An infectious process affecting a tooth. C26726 Infectious Disorder C90259 Pediatric Terminology C C78787 Purpura Purpura A small blood vessel hemorrhage into the skin and/or mucous membranes. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color. Small blood vessel hemorrhage into the skin and/or mucous membranes presenting as red or purplish patches. C36281 Integumentary System Finding C90259 Pediatric Terminology C C84473 Atrial Septal Defect Atrial Septal Defect The presence of a defect (opening) in the septum that separates the two atria of the heart. It can be congenital or acquired. The presence of a defect (opening) in the septum that separates the two atria of the heart. It can be congenital or acquired. C84482 Cardiac Septal Defects C90259 Pediatric Terminology C C84915 Necrotizing Enterocolitis Necrotizing Enterocolitis A fulminating disease of neonates in which there is extensive mucosal ulceration, pseudomembrane formation, submucosal hemorrhage, and necrosis usually of the right colon, cecum, terminal ileum, and appendix, possibly due to perinatal intestinal ischemia and bacterial invasion. Progression can lead to necrosis, perforation and/or scarring of the intestinal tract. A disease of neonates in which there is extensive mucosal ulceration, pseudomembrane formation, submucosal hemorrhage, and necrosis. C98996 Neonatal Disorder C90259 Pediatric Terminology C C84978 Osteochondrodysplasia Congenital Skeletal Dysplasia A term referring to disorders characterized by abnormalities in the development of bones and cartilage. A complex group of bone and cartilage disorders that result in abnormalities in the size and shape of the trunk, extremities, and/or skull. C89337 Congenital Musculoskeletal Defect C90259 Pediatric Terminology C C84989 Panuveitis Panuveitis A disorder characterized by inflammation of the entire uvea which includes the iris, ciliary body, and choroid. Causes include systemic infections, sarcoidosis, and cancers. Inflammation of all layers of the uvea. C26909 Uveitis C90259 Pediatric Terminology C C85231 Whooping Cough Whooping Cough A contagious bacterial respiratory infection caused by Bordetella pertussis. It is characterized by severe and uncontrollable cough, resulting in a whooping sound during breathing following the cough. A bacterial respiratory infection caused by Bordetella pertussis, which is characterized by severe and uncontrollable cough, resulting in a whooping sound during breathing following the cough. C26871 Respiratory System Disorder C90259 Pediatric Terminology C C87070 Hypotonia Hypotonia A condition of decreased tone of the skeletal muscles and diminished resistance to passive stretching. Abnormally low muscle tone. C100104 Signs or Symptoms C90259 Pediatric Terminology C C87085 Hypertonia Hypertonia A condition of increased muscle tone manifested by increased resistance of the muscle to passive stretching. Abnormally high muscle tone. C100104 Signs or Symptoms C90259 Pediatric Terminology C C92839 Oligohydramnios Oligohydramnios A lower than normal quantity of amniotic fluid in the amniotic sac as compared to normal values. Typically associated with an amniotic fluid index (AFI) of less than 5 cm or a single maximum vertical pocket (MVP) of less than 2 cm. A lower than normal quantity of amniotic fluid in the amniotic sac. Typically associated with an amniotic fluid index (AFI) of less than 5 cm or a single maximum vertical pocket (MVP) of less than 2 cm. C92719 Fetal Disorder C34941 Pregnancy Complication C90259 Pediatric Terminology C C9438 Chronic Renal Failure Chronic Renal Failure Impairment of the renal function due to chronic kidney damage. Impairment of the renal function due to chronic kidney damage. C3149 Kidney Disease C90259 Pediatric Terminology C C94475 Retching Retching Involuntary spasms of the stomach and esophagus resulting in vomiting or dry heaving. Involuntary spasms of the stomach and esophagus resulting in vomiting or dry heaving. C100104 Signs or Symptoms C90259 Pediatric Terminology C C94832 Systemic Inflammatory Response Syndrome Systemic Inflammatory Response Syndrome A generalized state of dysregulated inflammation induced by noninfectious processes. It is characterized by two or more of the following signs and symptoms: fever or hypothermia, increased heart rate, increased respiratory rate, and abnormal white blood cell count. A generalized state of dysregulated inflammation characterized by two or more of the following signs and symptoms: fever or hypothermia, increased heart rate, increased respiratory rate, and abnormal white blood cell count. C9229 Systemic Disorder C90259 Pediatric Terminology C C99016 Phrenic Nerve Injury Phrenic Nerve Injury Damage to the phrenic nerve. Damage to the phrenic nerve, resulting in paralysis of the ipsilateral hemidiaphragm. C3671 Injury C90259 Pediatric Terminology C C89345 Childhood Childhood Child Life Stage A time period that begins at the beginning of the human embryonic stage and continues until the end of adolescence. A time period that begins at the beginning of the human embryonic stage and continues until the end of adolescence. C89335 Life Stage C90259 Pediatric Terminology C C89889 Infancy Infancy Infant Stage A human life stage that begins at birth and continues until twelve complete months of age. A human life stage that begins at birth and continues until twelve complete months of age. C89345 Child Life Stage C90259 Pediatric Terminology C C102292 Distal Interphalangeal Joint 3 Distal Interphalangeal Joint 3 A ginglymoid (hinge) synovial joint within the third digit of the hand or foot connecting the middle and distal phalanges. A condyloid synovial joint within the third digit of the hand or foot connecting the middle and distal phalanges. (NCI) C32221 Body Part C90259 Pediatric Terminology C C102333 Proximal Interphalangeal Joint 3 Proximal Interphalangeal Joint 3 A ginglymoid (hinge) synovial joint within the third digit of the hand or foot connecting the proximal and middle phalanges. A condyloid synovial joint within the third digit of the hand or foot connecting the proximal and middle phalanges. (NCI) C32221 Body Part C90259 Pediatric Terminology C C111886 Diaper Dermatitis Diaper Dermatitis An inflammatory skin condition in the diaper area that may be caused by irritation or infection. An inflammatory skin condition in the diaper area that may be caused by irritation or infection. C3371 Integumentary System Disorder C90259 Pediatric Terminology C C112404 Quadrate Lobe of Liver Liver, Quadrate Lobe An oblong shaped area of the liver that is situated inferior to the right lobe, bounded by the anterior margin of the liver and the porta hepatis. An oblong shaped area of the liver that is situated inferior to the right lobe, bounded by the anterior margin of the liver and the porta hepatis. (CDISC) C32221 Body Part C90259 Pediatric Terminology C C116784 Circumscribed Morphea Circumscribed Morphea A type of morphea in which the lesions are circular or ovoid, and may be superficial or deep. The superficial lesions can have an indurated, waxy, ivory colored center with surrounding erythema or violaceous color during the active stage. Deep lesions can be sclerotic and depressed from underlying atrophy, and may show minimal skin color changes. When there are several (greater than or equal to 4), larger (greater than 3cm) lesions on two or more body areas this is classified as "generalized morphea". A type of morphea in which the lesions are circular or ovoid, and may be superficial or deep. The superficial lesions can have an indurated, waxy, ivory colored center with surrounding erythema or violaceous color during the active stage. Deep lesions can be sclerotic and depressed from underlying atrophy, and may show minimal skin color changes. When there are several (greater than or equal to 4), larger (greater than 3 cm) lesions on two or more body areas this is classified as "generalized morphea". C72069 Morphea C90259 Pediatric Terminology C C116994 Lupus Anticoagulant Disorder Lupus Anticoagulant Disorder A hypercoaguable state that results from the presence of the immunoglobulin known as Lupus Anticoagulant. The antibody interacts with cell membrane phospholipids, causing increased aggregation and adhesion of platelets, which causes increased clot formation. Though the majority of patients who test positive for lupus anticoagulant do not have lupus, those individuals afflicted with lupus have a higher probability of developing the antibody. C2889 Autoimmune Disease C26323 Hematological Disorder C90259 Pediatric Terminology C C118857 Lamellar Laceration of the Globe Lamellar Laceration of the Globe Traumatic injury to the globe, resulting in a partial thickness wound of the eyewall (cornea and/or sclera). (adapted from the Birmingham Eye Trauma Terminology System (BETTS)) Traumatic injury to the globe, resulting in a partial thickness wound of the eyewall (cornea and/or sclera). (adapted from the International Society of Ocular Trauma-Birmingham Eye Trauma Terminology System (BETTS)) C118747 Closed Globe Injury C90259 Pediatric Terminology C C12250 Cervical Esophagus Esophagus, Cervical Clinical esophageal segment composed of skeletal muscle. It corresponds to the superior part of the upper third topographic segment of the esophagus. Clinical esophageal segment composed of skeletal muscle. It corresponds to the superior part of the upper third topographic segment of the esophagus. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12251 Thoracic Esophagus Esophagus, Thoracic Clinical esophageal segment composed of smooth muscle. It includes the middle third topographic segment, as well as parts of the upper and lower thirds. Clinical esophageal segment composed of smooth muscle. It includes the middle third topographic segment, as well as parts of the upper and lower thirds. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12258 Body of Stomach Body of Stomach The main section of the digestive tube that connects the esophagus to the small intestine. The body proper excludes the upper and lower sections of the fundus and pyloric portion respectively. The main section of the digestive tube that connects the esophagus to the small intestine. The body proper excludes the upper and lower sections of the fundus and pyloric portion respectively. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12262 Greater Curvature of the Stomach Greater Curvature of the Stomach The lateral and inferior border of the stomach. Attached to it is the greater omentum. The lateral and inferior border of the stomach. Attached to it is the greater omentum. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12347 Orbit Orbit The bony cavity of the skull which contains the eye, anterior portion of the optic nerve, ocular muscles and ocular adnexa. Seven bones contribute to the structure of the orbit: the frontal, maxillary, zygomatic, sphenoid, lacrimal, ethmoid, and palatine bones. The bony cavity of the skull which contains the eye, anterior portion of the optic nerve, ocular muscles and ocular adnexa. Seven bones contribute to the structure of the orbit: the frontal, maxillary, zygomatic, sphenoid, lacrimal, ethmoid, and palatine bones. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12392 Liver Liver A triangular-shaped organ located under the diaphragm in the right hypochondrium. It is the largest internal organ of the body, weighting up to 2 kg. Metabolism and bile secretion are its main functions. It is composed of cells which have the ability to regenerate. A triangular-shaped organ located under the diaphragm in the right hypochondrium. It is the largest internal organ of the body, weighting up to 2 kg. Metabolism and bile secretion are its main functions. It is composed of cells which have the ability to regenerate. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12393 Pancreas Pancreas An organ behind the lower part of the stomach that is the shape of a fish and about the size of a hand. It is a compound gland composed of both exocrine and endocrine tissues. The endocrine pancreas makes insulin so that the body can use glucose (sugar) for energy. The exocrine pancreas makes enzymes that help the body digest food. Spread all over the pancreas are areas called the Islets of Langerhans. The cells in these areas each have a special purpose. The alpha cells make glucagon, which raises the level of glucose in the blood; the beta cells make insulin; the delta cells make somatostatin. There are also PP cells and D1 cells, about which little is known. An organ behind the lower part of the stomach that is the shape of a fish and about the size of a hand. It is a compound gland composed of both exocrine and endocrine tissues. The endocrine pancreas makes insulin so that the body can use glucose (sugar) for energy. The exocrine pancreas makes enzymes that help the body digest food. Spread all over the pancreas are areas called the Islets of Langerhans. The cells in these areas each have a special purpose. The alpha cells make glucagon, which raises the level of glucose in the blood; the beta cells make insulin; the delta cells make somatostatin. There are also PP cells and D1 cells, about which little is known. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12410 Prostate Gland Prostate Gland The walnut shaped accessory sex gland of the male reproductive system. It is located in the pelvis just below the bladder, surrounding the prostatic part of the urethra. The prostate gland secretes a fluid which is part of the semen. The walnut shaped accessory sex gland of the male reproductive system. It is located in the pelvis just below the bladder, surrounding the prostatic part of the urethra. The prostate gland secretes a fluid which is part of the semen. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12426 Salivary Gland Salivary Gland An exocrine gland that secretes saliva. Salivary glands are mostly located in and around the oral cavity. An exocrine gland that secretes saliva. Salivary glands are mostly located in and around the oral cavity. (CDISC) C32221 Body Part C90259 Pediatric Terminology C C12432 Spleen Spleen An organ that is part of the hematopoietic and immune systems. It is composed of the white pulp and the red pulp and is surrounded by a capsule. It is located in the left hypochondriac region. Its functions include lymphocyte production, blood cell storage, and blood cell destruction. An organ that is part of the hematopoietic and immune systems. It is composed of the white pulp and the red pulp and is surrounded by a capsule. It is located in the left hypochondriac region. Its functions include lymphocyte production, blood cell storage, and blood cell destruction. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12433 Thymus Gland Thymus Gland A bi-lobed organ surrounded by a connective tissue capsule. It is located in the upper anterior portion of the chest, behind the sternum. It is composed predominantly of lymphocytes and fewer epithelial cells. Connective tissue septa separate the lobes into lobules. The lobules contain an outer portion (cortical zone) which is rich in lymphocytes and an inner portion (medullary zone) which is rich in epithelial cells. It is an organ essential for the development of the immune system. Its function is the maturation of the progenitor lymphoid cells to thymocytes and subsequently to mature T-cells. It reaches its greatest weight at puberty and subsequently begins to involute. A bi-lobed organ surrounded by a connective tissue capsule. It is located in the upper anterior portion of the chest, behind the sternum. It is composed predominantly of lymphocytes and fewer epithelial cells. Connective tissue septa separate the lobes into lobules. The lobules contain an outer portion (cortical zone) which is rich in lymphocytes and an inner portion (medullary zone) which is rich in epithelial cells. It is an organ essential for the development of the immune system. Its function is the maturation of the progenitor lymphoid cells to thymocytes and subsequently to mature T-cells. It reaches its greatest weight at puberty and subsequently begins to involute. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12442 Medulla Oblongata Medulla Oblongata The lower portion of the brainstem located between the pons and brainstem. This structure contains several descending and ascending tracts, lower cranial nerve nuclei, a significant proportion of the reticular system of the brainstem and other structures. The lower portion of the brainstem located between the pons and brainstem. This structure contains several descending and ascending tracts, lower cranial nerve nuclei, a significant proportion of the reticular system of the brainstem and other structures. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12443 Cerebral Cortex Cerebral Cortex The outer layer of the cerebrum composed of neurons and unmyelinated nerve fibers. It is responsible for memory, attention, consciousness and other higher levels of mental function. The outer layer of the cerebrum composed of neurons and unmyelinated nerve fibers. It is responsible for memory, attention, consciousness and other higher levels of mental function. (CDISC) C32221 Body Part C90259 Pediatric Terminology C C12470 Skin Skin An organ that constitutes the external surface of the body. It consists of the epidermis, dermis, and skin appendages. An organ that constitutes the external surface of the body. It consists of the epidermis, dermis, and skin appendages. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12502 Tympanic Membrane Tympanic Membrane A thin membrane that separates the external auditory canal from the middle ear. The movement of the tympanic membrane in response to air pressure changes in the external ear facilitates the transmission of sound energy by causing vibration of the ossicular chain. A thin membrane that separates the external auditory canal from the middle ear. The movement of the tympanic membrane in response to air pressure changes in the external ear facilitates the transmission of sound energy by causing vibration of the ossicular chain. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12503 Mastoid Process Mastoid Process A honeycombed section of bone located near the base of the skull, protruding behind the outer ear. It is connected to the middle ear. A honeycombed section of bone located near the base of the skull, protruding behind the outer ear. It is connected to the middle ear. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12510 Mesencephalon Midbrain The uppermost portion of the brainstem located between the pons and the diencephalon. The midbrain contains the cerebral peduncles, oculomotor, trochlear and red nuclei, substantia nigra and various other nuclei and tracts. The uppermost portion of the brainstem located between the pons and the diencephalon. The midbrain contains the cerebral peduncles, oculomotor, trochlear and red nuclei, substantia nigra and various other nuclei and tracts. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12511 Pons Varolii Pons Varolii The middle portion of the brainstem located between the midbrain and the medulla oblongata. The fourth ventricle lies dorsal to the pons which also contains the motor trigeminal nuclei and the abducens nuclei. The cerebellum contributes a large number of afferent fibers to the pons. The middle portion of the brainstem located between the midbrain and the medulla oblongata. (CDISC) C32221 Body Part C90259 Pediatric Terminology C C12683 Bronchus Bronchus Tubular structure in continuation with the trachea, serving as air passage. It terminates in the lung (terminal bronchiole). Tubular structure in continuation with the trachea, serving as air passage. It terminates in the lung (terminal bronchiole). (NCI) C32221 Body Part C90259 Pediatric Terminology C C12702 Diaphragm Diaphragm Fibromuscular tissue that separates the thoracic from the abdominal cavity. It increases the volume of the thoracic cavity through contractions, thus facilitating respiration. Fibromuscular tissue that separates the thoracic from the abdominal cavity. It increases the volume of the thoracic cavity through contractions, thus facilitating respiration. (CDISC) C32221 Body Part C90259 Pediatric Terminology C C12728 Cardiac Atrium Heart, Atrium The paired upper chambers of the heart. The left atrium receives oxygenated blood from the pulmonary vein and pumps blood into the left ventricle. The right atrium receives venous deoxygenated blood from the entire body via the superior and inferior vena cavae and pumps blood into the right ventricle. The paired upper chambers of the heart. The left atrium receives oxygenated blood from the pulmonary vein and pumps blood into the left ventricle. The right atrium receives venous deoxygenated blood from the entire body via the superior and inferior vena cavae and pumps blood into the right ventricle. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12736 Intestine Intestine The portion of the gastrointestinal tract between the stomach and the anus. It includes the small intestine and large intestine. The portion of the gastrointestinal tract between the stomach and the anus. It includes the small intestine and large intestine. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12739 Renal Cortex Kidney, Cortex The outer part of the renal parenchyma beneath the renal capsule. It contains glomeruli and tubules. The outer zone of the KIDNEY, beneath the capsule, consisting of KIDNEY GLOMERULUS; KIDNEY TUBULES, DISTAL; and KIDNEY TUBULES, PROXIMAL. (MSH2001) (CDISC) C32221 Body Part C90259 Pediatric Terminology C C12740 Renal Medulla Kidney, Medulla The inner part of the renal parenchyma. It consists mostly of collecting tubules and is organized in sections called pyramids. The internal portion of the kidney, consisting of striated conical masses, the renal pyramids, whose bases are adjacent to the cortex and whose apices form prominent papillae projecting into the lumen of the minor calyces. (MSH2001) (CDISC) C32221 Body Part C90259 Pediatric Terminology C C12743 Lens Lens A biconvex transparent structure of the eye through which light is focused on the retina. The lens sits behind the iris and is supported by the zonule, which connects it to the ciliary body. The lens is an avascular structure. A biconvex transparent structure of the eye through which light is focused on the retina. The lens sits behind the iris and is supported by the zonule, which connects it to the ciliary body. The lens is an avascular structure. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12770 Peritoneum Peritoneum The tissue that lines the wall of the abdominal cavity, intestine, and mesentery. It consists of the parietal peritoneum that covers the inside of the abdominal wall and the visceral peritoneum that covers the surface of the intestine and mesentery. The tissue that lines the wall of the abdominal cavity, intestine, and mesentery. It consists of the parietal peritoneum that covers the inside of the abdominal wall and the visceral peritoneum that covers the surface of the intestine and mesentery. (NCI) C32221 Body Part C90259 Pediatric Terminology C C12996 Vestibulocochlear Nerve Vestibulocochlear Nerve The eighth cranial nerve composed of the acoustic nerve and the vestibular nerve. The nerve travels from the inner ear, enters the cranial cavity through the internal auditory foramen and joins the brainstem. The auditory nerve conveys impulses from the cochlea of the inner ear to the auditory nuclei of the brainstem. The vestibular nerve carries information from the labyrinths of the inner ear to the vestibular nuclei of the brainstem. The eighth cranial nerve. (CDISC) C32221 Body Part C90259 Pediatric Terminology C C13041 Body Body The entire physical structure of an organism. It is composed of anatomic systems, regions, cavities, and spaces. The entire physical structure of an organism. It is composed of anatomic systems, regions, cavities, and spaces. (NCI) C32221 Body Part C90259 Pediatric Terminology C C16423 Child Child A person who is not yet an adult. The specific cut-off age will vary by purpose. C25190 Person C90259 Pediatric Terminology C C25307 Contralateral Contralateral On or relating to the opposite side of the body. Having to do with the opposite side of the body, in relation to a pre-existing reference point. (CDISC) C92722 Qualitative Concept C90259 Pediatric Terminology C C26767 Eye Disorder Eye Disorder A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. C2991 Disease or Disorder C90259 Pediatric Terminology C C26821 Lymphadenitis Lymphadenitis Acute or chronic inflammation of one or more lymph nodes. It is usually caused by an infectious process. Inflammation of one or more lymph nodes. C3507 Immune System Disorder C90259 Pediatric Terminology C C26871 Respiratory System Disorder Respiratory System Disorder A non-neoplastic or neoplastic disorder that affects the respiratory system. Representative examples include pneumonia, chronic obstructive pulmonary disease, pulmonary failure, lung adenoma, lung carcinoma, and tracheal carcinoma. C2991 Disease or Disorder C90259 Pediatric Terminology C C26884 Sleep Apnea Sleep Apnea Cessation of breathing for short periods during sleep. It is classified as obstructive, central, or mixed obstructive-central. It can occur at any age but it is more frequent in people over forty. Risk factors include male sex and obesity. The cessation of breathing for periods of time during sleep. C26698 Apnea C90259 Pediatric Terminology C C26974 Mixed Hearing Loss Mixed Hearing Loss Hearing loss characterized by a combination of conductive and sensorineural hearing loss. It is caused by problems in both the inner ear and middle or outer ear. A combination of conductive and sensorineural hearing loss. C35731 Hearing Loss C90259 Pediatric Terminology C C2701 Therapeutic Immune Globulin Immune Globulin A preparation of plasma proteins derived from the pooled plasma of adult donors. Largely comprised of IgG antibodies, therapeutic immune globulin provides passive immunization by increasing the recipient's serum levels of circulating antibodies. IgG antibodies have multiple functions, including binding to and neutralizing bacterial toxins; opsonization of pathogens; activation of complement; and suppression of pathogenic cytokines and phagocytes through binding to CD5, interleukin-1a (IL-1a), interleukin 6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), and T-cell receptors. Therapeutic immune globulin may diminish pathogenic mechanisms in some autoimmune diseases by binding to and inhibiting the activity of autoantibodies. (NCI04) A blood product derived from pooled IgG antibodies extracted from donor plasma delivered parenterally. It is used to treat multiple disorders, including immunodeficiencies, autoimmune disorders, and active infections. C1909 Pharmacologic Substance C90259 Pediatric Terminology C C2884 Rheumatoid Arthritis Rheumatoid Arthritis A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor. A chronic, inflammatory condition manifesting primarily as a symmetric, erosive, polyarthritis that spares the axial skeleton and is typically associated with rheumatoid factor and anti-citrullinated protein antibodies. C2883 Arthritis C90259 Pediatric Terminology C C3079 Heart Disorder Heart Disease A non-neoplastic or neoplastic disorder that affects the heart and/or the pericardium. Representative examples include endocarditis, pericarditis, atrial myxoma, cardiac myeloid sarcoma, and pericardial malignant mesothelioma. C2931 Cardiovascular Disorder C90259 Pediatric Terminology C C3081 Cardiac Neoplasm Neoplasm of Heart A benign or malignant neoplasm that affects the heart and/or the pericardium. Representative examples include atrial myxoma, cardiac myeloid sarcoma, and pericardial malignant mesothelioma. C3262 Neoplasm C90259 Pediatric Terminology C C32478 Dorsalis Pedis Artery Dorsalis Pedis Artery An artery of the dorsal surface of the foot, originating from the anterior tibial artery of the lower leg. The following arterial branches originate from the dorsalis pedis artery: the arcuate artery of the foot and deep plantar artery. An artery of the dorsal surface of the foot, originating from the anterior tibial artery of the lower leg. The following arterial branches originate from the dorsalis pedis artery: the arcuate artery of the foot and deep plantar artery. (NCI) C32221 Body Part C90259 Pediatric Terminology C C3282 Nystagmus Nystagmus Involuntary movements of the eyeballs. The presence or absence of nystagmus is often used in the diagnosis of a variety of neurological and visual disorders. Repetitive and involuntary movement of the eyes. C99208 Eye Finding C90259 Pediatric Terminology C C33073 Mediastinal Lymph Node Mediastinal Lymph Node A lymph node located in the mediastinum. Mediastinal lymph nodes are arranged in three groups, one on the lateral, another on the medial, and a third on the anterior aspect of the vessels; the third group is, however, sometimes absent. A lymph node located in the mediastinum. Mediastinal lymph nodes are arranged in three groups, one on the lateral, another on the medial, and a third on the anterior aspect of the vessels; the third group is, however, sometimes absent. (NCI) C32221 Body Part C90259 Pediatric Terminology C C33200 Olecranon Olecranon A prominence at the proximal end of the ulna. It forms the tip of the elbow. A prominence at the proximal end of the ulna. It forms the tip of the elbow. (NCI) C32221 Body Part C90259 Pediatric Terminology C C34610 Polyostotic Fibrous Dysplasia Polyostotic Fibrous Dysplasia of Bone Fibrous dysplasia affecting more than one bone. When it is associated with café-au-lait skin pigmentation and endocrine disorders, it is known as McCune-Albright syndrome. C3101 Genetic Disorder C107377 Musculoskeletal System Disorder C90259 Pediatric Terminology C C39298 Adolescence Adolescence A human life stage that begins at twelve years of age and continues until twenty-one complete years of age, generally marked by the beginning of puberty and lasting to the beginning of adulthood. A human life stage that begins at twelve years of age and continues until twenty-one complete years of age, generally marked by the beginning of puberty and lasting to the beginning of adulthood. C89345 Child Life Stage C90259 Pediatric Terminology C C43245 Pyramidal Tract Dysfunction Pyramidal Tract Syndrome Dysfunction of the corticospinal (pyramidal) tracts of the spinal cord. Symptoms include increased muscle tone in the lower extremities, hyperreflexia, positive Babinski, and decreased fine motor coordination. Dysfunction of the corticospinal tracts of the spinal cord. C2934 Central Nervous System Disorder C90259 Pediatric Terminology C C4781 Benign Brain Neoplasm Benign Brain Tumor A primary, slow growing, noninvasive neoplasm of the brain. In children, astrocytomas of the cerebellum represent relatively common benign brain neoplasms. In adults meningiomas, neurilemomas and pituitary tumors comprise the majority of benign tumors. An abnormal intracranial solid mass or growth arising within the brain without histologic features suggesting the potential to metastasize. C2907 Brain Tumor C90259 Pediatric Terminology C C66930 Angiotensin II Receptor Antagonist Angiotensin II Receptor Antagonist A class of agents that act by selectively inhibiting angiotensin II receptor activation in the renin-angiotensin-aldosterone system. Angiotensin II receptor antagonists bind to and block the activation of angiotensin II type 1 (AT1) receptors, thereby reducing production and secretion of aldosterone, amongst other actions. The combined effects result in reduction of blood pressure. Although this class of agents is also used in diabetic nephropathy (kidney damage due to diabetes) and congestive heart failure, it is primarily used for the treatment of hypertension in cases where the patient is intolerant of ACE inhibitor therapy. A pharmaceutical agent that selectively inhibits angiotensin II receptor activation in the renin-angiotensin-aldosterone system reducing production and secretion of aldosterone, amongst other actions. The combined effects result in reduction of blood pressure. It is primarily used for the reduction of proteinuria and the treatment of hypertension in cases where the patient is intolerant of ACE inhibitor therapy. C1909 Pharmacologic Substance C90259 Pediatric Terminology C C79859 Abnormal Virilization Virilization The abnormal development of male secondary sexual characteristics due to excessive androgens. The abnormal development of male secondary sexual characteristics due to excessive androgens. C36285 Endocrine System Finding C90259 Pediatric Terminology C C89331 Early Adolescence Early Adolescence A human life stage that begins at twelve years of age and continues until eighteen complete years of age. This phase marks the start of physical, physiological and psychological changes that characterize pubertal growth and development. A human life stage that begins at twelve years of age and continues until eighteen complete years of age. This phase marks the start of physical, physiological and psychological changes that characterize pubertal growth and development. C39298 Adolescence C90259 Pediatric Terminology C C89344 Late Adolescence Late Adolescence A human life stage that begins at nineteen years of age and continues until twenty-one complete years of age. This phase includes the final stages of pubertal growth and development as well as the attainment of significant psycho-social milestones. A human life stage that begins at nineteen years of age and continues until twenty-one complete years of age. This phase includes the final stages of pubertal growth and development as well as the attainment of significant psycho-social milestones. C39298 Adolescence C90259 Pediatric Terminology C C89346 Early Childhood Early Childhood A human life stage that begins at two years of age and continues until five complete years of age. A human life stage that begins at two years of age and continues until five complete years of age. C89345 Child Life Stage C90259 Pediatric Terminology C C89347 Middle Childhood Middle Childhood A human life stage that begins at six years of age and continues until eleven complete years of age. A human life stage that begins at six years of age and continues until eleven complete years of age. C89345 Child Life Stage C90259 Pediatric Terminology C C89885 Fetal Stage Fetal Stage A human life stage, during prenatal development, that typically begins at the beginning of nine weeks after fertilization (full formation of the embryo) and continues until birth. A human life stage, during prenatal development, that typically begins at the beginning of nine weeks after fertilization (full formation of the embryo) and continues until birth. C89335 Life Stage C90259 Pediatric Terminology C C89890 Toddler Stage Toddler Stage A human life stage that begins at thirteen months of age and continues until twenty-four complete months of age. A human life stage that begins at thirteen months of age and continues until twenty-four complete months of age. C89345 Child Life Stage C90259 Pediatric Terminology C C9118 Sarcoma Sarcoma A usually aggressive malignant neoplasm of the soft tissue or bone. It arises from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The prognosis depends largely on the degree of differentiation (grade) of the neoplasm. Representative subtypes are liposarcoma, leiomyosarcoma, osteosarcoma, and chondrosarcoma. C9305 Malignant Neoplasm C90259 Pediatric Terminology C C99048 Retinopathy of Prematurity Stage 2 Intraretinal Ridge Retinopathy of Prematurity Stage 2 - Intraretinal Ridge An ophthalmoscopic finding that references retinopathy of prematurity characterized by the presence of an elevated ridge. A vasoproliferative condition of the retina seen in very immature newborn infants. Stage 2 is defined by an intraretinal ridge, the ridge arises from the demarcation line and has height and width, which extends above the plane of the retina. The ridge may change from white to pink and vessels may leave the plane of the retina posterior to the ridge to enter it. C34982 Retinopathy of Prematurity C90259 Pediatric Terminology C C99049 Retinopathy of Prematurity Stage 3 Ridge with Extraretinal Fibroblastic Proliferation Retinopathy of Prematurity Stage 3 - Ridge with Extraretinal Fibrovascular Proliferation An ophthalmoscopic finding that references retinopathy of prematurity characterized by the presence of extraretinal fibrovascular tissue. A vasoproliferative condition of the retina seen in very immature newborn infants. Stage 3 is defined by a ridge with extraretinal fibrovascular proliferation, the neovascularization extends from the ridge into the vitreous. This extraretinal proliferating tissue is continuous with the posterior aspect of the ridge, causing a ragged appearance as the proliferation becomes more extensive. C34982 Retinopathy of Prematurity C90259 Pediatric Terminology C C99050 Retinopathy of Prematurity Stage 4 Subtotal Retinal Detachment Retinopathy of Prematurity Stage 4 - Subtotal Retinal Detachment An ophthalmoscopic finding that references retinopathy of prematurity characterized by the presence of subtotal retinal detachment. A vasoproliferative condition of the retina seen in very immature newborn infants. Stage 4 is defined by subtotal retinal detachment. The retinal detachments are generally concave and most are circumferentially oriented. Retinal detachments usually begin at the point of fibrovascular attachment to the vascularized retina and the extent of detachment depends on the amount of neovascularization present. Stage 4A is defined by retinal detachment which spares the macula. Stage 4B is defined by retinal detachment involving the macula. C34982 Retinopathy of Prematurity C90259 Pediatric Terminology C C99051 Retinopathy of Prematurity Stage 5 Total Retinal Detachment Retinopathy of Prematurity Stage 5 - Total Retinal Detachment An ophthalmoscopic finding that references retinopathy of prematurity characterized by the presence of total retinal detachment. A vasoproliferative condition of the retina seen in very immature newborn infants. Stage 5 is defined by total retinal detachment. The retinal detachments are generally tractional and usually funnel shaped. The configuration of the funnel itself is used for subdivision of this stage depending if the anterior and posterior portions are open or narrowed. C34982 Retinopathy of Prematurity C90259 Pediatric Terminology C C99135 Embryonic Stage Embryonic Stage A human life stage, during prenatal development, that begins at fertilization and typically continues until the end of eight weeks after fertilization, with full formation of the embryo. A human life stage, during prenatal development, that begins at fertilization and typically continues until the end of eight weeks after fertilization, with full formation of the embryo. C89335 Life Stage C90259 Pediatric Terminology C C103172 Congenital Bleeding Disorder Congenital Bleeding Disorder Congenital Bleeding Defect|Congenital Coagulation Defect A bleeding disorder that is diagnosed during childhood, with the presenting symptom of excessive bleeding. C2902 Coagulopathy C104003 Congenital Hematological Disorder C90259 Pediatric Terminology C C117337 Placental Finding Placental Findings Clinical and laboratory findings about the placenta. C3367 Finding C90259 Pediatric Terminology C C12219 Anatomic Structure, System, or Substance Anatomic Structure, System, or Substance A human biological structure, fluid or other substance; excludes single molecular entities. C90259 Pediatric Terminology C90259 Pediatric Terminology C C122638 Ostomy Site Ostomy Site The anatomic location of a surgically created ostomy. C32221 Body Part C90259 Pediatric Terminology C C26323 Hematologic and Lymphocytic Disorder Hematologic Disorder Hematological Disorder A neoplastic or non-neoplastic disorder that affects the production and proliferation of the hematopoietic cells including lymphoid cells, the synthesis of hemoglobin, and/or the mechanisms of coagulation. C2991 Disease or Disorder C90259 Pediatric Terminology C C26857 Placenta Disorder Placental Disorder A non-neoplastic or neoplastic disorder that affects the placenta. Representative examples include chorioamnionitis, hemangioma, and choriocarcinoma. C35169 Pregnancy Disorder C90259 Pediatric Terminology C C90338 Maternal Postnatal Stage Maternal Postnatal Stage Postnatal Stage The stage in the life of a mother after she has given birth. C90337 Maternal Life Stage C90259 Pediatric Terminology C C90339 Maternal Prenatal Stage Maternal Prenatal Stage Prenatal Stage The stage in the life of a mother during which she is pregnant. C90337 Maternal Life Stage C90259 Pediatric Terminology C C90340 Maternal Preconception Stage Maternal Preconception Stage Preconception Stage The stage in the life of a female during which she is attempting to get pregnant. C90337 Maternal Life Stage C90259 Pediatric Terminology C C90342 Developmental Milestone Developmental Milestone Developmental Milestones Physical or behavioral signs of maturation or skills gained by a developing child, which should be achieved by a given age that provide important information regarding the child's development. The milestones are different for each age range. Failure to achieve a particular milestone by a given age is indicative of developmental delay. C3367 Finding C90259 Pediatric Terminology C C90346 Behavior during Childhood Behavior during Childhood Child Behavior Observed actions from individuals between 2 and 18 years of age. C16326 Behavior C90259 Pediatric Terminology C C91717 Diphtheria Toxoid/Tetanus Toxoid/Acellular Pertussis Vaccine Adsorbed DTP vaccine A vaccine containing detoxified tetanus toxoid, detoxified diphtheria toxoid and acellular pertussis antigens, adsorbed on aluminum phosphate, with active immunizing activity against diphtheria, tetanus and pertussis. The acellular pertussis vaccine components, produced by Bordetella pertussis, are detoxified pertussis toxin (PT), filamentous hemagglutinin (FHA), pertactin (PRN) and fimbriae types 2 and 3 (FIM). Intramuscular injection with this vaccine activates the immune system to develop antibodies against tetanus toxin, diphtheria toxin and B. pertussis antigens. C2848 Polyvalent Vaccine C90259 Pediatric Terminology C C97171 Congenital Digestive System Disorder Congenital Gastrointestinal Disorder Congenital Abnormality of the Digestive System An abnormality of the digestive system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C2990 Gastrointestinal Disorder C90259 Pediatric Terminology C C97173 Congenital Respiratory System Disorder Congenital Abnormality of the Respiratory System An abnormality of the respiratory system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C26871 Respiratory System Disorder C90259 Pediatric Terminology C C97174 Congenital Skin Disorder Congenital Skin Disorder Congenital Abnormality of the Skin A skin abnormality that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C3371 Integumentary System Disorder C90259 Pediatric Terminology C C98828 Small Intestine Atresia Small Intestine Atresia Atresia of Small Intestine A congenital malformation characterized by the absence of a normal opening in a part of the small intestine. C97171 Congenital Abnormality of the Digestive System C90259 Pediatric Terminology C C115788 Subcapsular Renal Hematoma Subcapsular Hematoma A collection of blood between the renal capsule and the renal parenchyma. A collection of blood between the renal capsule and the renal parenchyma. C50579 Hematoma C90259 Pediatric Terminology D C118464 Pediatric Adverse Events Terminology Pediatric Adverse Events Terminology Terminology developed by the National Children's Study and an international group of clinicians and informaticists to support the reporting of adverse events in the pediatric population. C90259 Pediatric Terminology D C118466 Perinatal Terminology Perinatal Terminology Terminology developed by the National Children's Study and an international group of clinicians and informaticists to support the reporting of events in the perinatal population. C90259 Pediatric Terminology D C118467 Pediatric Endocrinology Terminology Pediatric Endocrinology Terminology C90259 Pediatric Terminology D C118468 Pediatric Rheumatology Terminology Pediatric Rheumatology Terminology Terminology developed by a collaborative effort of the National Institute of Child Health and Human Development, the National Cancer Institute's Enterprise Vocabulary Services, and an international group of clinicians and informaticists to support the reporting of events observed in clinical care and research in children and adolescents seen by experts in diseases of joints, muscles, and bones. C90259 Pediatric Terminology D C122636 Pediatric Medical Device Terminology Pediatric Medical Device Terminology Terminology developed to provide a list of medical devices used in the pediatric population. C90259 Pediatric Terminology D C62950 Medical Device or Device Component Dislodged or Dislocated Medical Device or Device Component Dislodged or Dislocated An issue associated with a medical device or a piece of the medical device that has moved from the intended location. C78254 Device Complication C90259 Pediatric Terminology D C62996 Medical Device Failure or Malfunction Medical Device Failure or Malfunction An adverse event and reportable event where a medical device may have caused or contributed to a death or serious injury. C78254 Device Complication C90259 Pediatric Terminology D C74456 CDISC SDTM Anatomical Location Terminology CDISC SDTM Anatomical Location Terminology Terminology codelist used with Anatomical Locations within the Clinical Data Interchange Standards Consortium Study Data Tabulation Model. C90259 Pediatric Terminology D C89506 Newborn Screening Terminology Newborn Screening Terminology Terminology for concepts associated with neonatal and infant examination contributed by the National Institute of Child Health and Human Development. C90259 Pediatric Terminology D C96388 Pediatric Immunization Terminology Pediatric Immunization Terminology Terminology for concepts associated with immunization in children (birth to 21 years of age) contributed by the National Institute of Child Health and Human Development. C90259 Pediatric Terminology D C97150 Neurological Development Terminology Neurological Development Terminology Terminology for concepts associated with neurological development in children contributed by the National Institute of Child Health and Human Development. C90259 Pediatric Terminology D C99073 CDISC SDTM Laterality Terminology CDISC SDTM Laterality Terminology Terminology associated with the laterality codelist of the Clinical Data Interchange Standards Consortium (CDISC) Study Data Tabulation Model (SDTM). C90259 Pediatric Terminology D C99074 CDISC SDTM Directionality Terminology CDISC SDTM Directionality Terminology Terminology associated with the directionality codelist of the Clinical Data Interchange Standards Consortium (CDISC) Study Data Tabulation Model (SDTM). C90259 Pediatric Terminology D C99147 Neonatal Research Network Terminology Neonatal Research Network Terminology Terminology developed to support the efforts of the Neonatal Research Network. Terminology for concepts associated with neonatal research contributed by four neonatal research networks: Vermont-Oxford Network (VON), Children's Hospital of Philadelphia (CHOP), NICHD Neonatal Research Network (NICHD-NRN) and NICHD Pediatric Terminology. C90259 Pediatric Terminology