C	C119996	Pediatric Osteoporosis	Pediatric Osteoporosis	Idiopathic Juvenile Osteoporosis	The finding of one or more vertebral compression (crush) fractures in the absence of local disease or high-energy trauma or the presence of both a clinically significant fracture history and BMD Z-score less than or equal to -2.0. A clinically significant fracture history is one or more of the following: 1) two or more long bone fractures by age ten years; 2) three or more long bone fractures at any age up to age nineteen years. (from 2013 International Society for Clinical Densitometry definition of Osteoporosis-Pediatric)	Osteoporosis of unknown etiology that presents in childhood.	C107377	Musculoskeletal System Disorder			C118468	Pediatric Rheumatology Terminology	
C	C34807	Marfan Syndrome	Marfan Syndrome	Marfan's Syndrome	A genetic syndrome inherited as an autosomal dominant trait. It is caused by mutations in the FBN1 gene. It is characterized by tall stature, elongated extremities, mitral valve prolapse, aortic dilatation, aortic dissection, and subluxation of the lens.	An autosomal dominant condition caused by mutation(s) in the FBN1 gene, encoding fibrillin-1. This condition is characterized by tall stature, disproportionately long limbs, arachnodactyly, and hyperextensible joints; additional features may include scoliosis, kyphosis, pectus excavatum/carinatum, mitral valve prolapse, aortic dilatation, aortic dissection, and upward subluxation of one or both ocular lens.	C3101	Genetic Disorder	C97075	Hereditary Connective Tissue Disorder	C118468	Pediatric Rheumatology Terminology	
C	C84978	Osteochondrodysplasia	Osteochondrodysplasia	Congenital Skeletal Dysplasia|Skeletal Dysplasia	A term referring to disorders characterized by abnormalities in the development of bones and cartilage.	Abnormalities in development and growth of bone and cartilage.	C89337	Congenital Musculoskeletal Defect			C118468	Pediatric Rheumatology Terminology