A C124224 Pigmentary Change in Skin Pigmentary Change of Skin Abnormal skin pigmentation. Changes in skin pigmentation. C36281 Integumentary System Finding C118464 Pediatric Adverse Events Terminology 10000165 Abnormal pigmentation A C3568 Malignant Brain Neoplasm Malignant Brain Tumor A primary or metastatic malignant neoplasm affecting the brain. An abnormal solid mass arising within the brain with histologic features suggesting the potential to metastasize. C9305 Cancer C118464 Pediatric Adverse Events Terminology 10025783 Malignant neoplasm of brain C C113743 Excessive Bruising Excessive Bruising Bruising that is disproportionately high to the amount of trauma received or reported. Bruising that is disproportionally high for the associated trauma. C100104 Sign or Symptom C118464 Pediatric Adverse Events Terminology C C117246 Decreased Concentration Decreased Concentration Reduced ability to sustain attention. Impaired ability to sustain attention. C3858 Mental and Behavioral Signs and Symptoms C118464 Pediatric Adverse Events Terminology C C113144 Central Hypothyroidism Central Hypothyroidism Abnormally low levels of thyroid hormones due to a disorder originating within the hypothalamic-pituitary axis. Abnormally low levels of thyroid hormones due to a disorder originating within the hypothalamic pituitary axis. C3009 Endocrine System Disorder C118464 Pediatric Adverse Events Terminology C C114798 Elevated Blood Pressure Measurement Elevated Blood Pressure Measurement An abnormally high blood pressure reading. An abnormally high blood pressure reading. C35552 Cardiovascular System Finding C118464 Pediatric Adverse Events Terminology C C114845 Extraosseous Calcification Extraosseous Calcification Deposition of calcium in tissues outside of bone. Deposition of calcium in tissues outside of bone. C9229 Systemic Disorder C118464 Pediatric Adverse Events Terminology C C115988 Neonatal Herpes Simplex Infection Neonatal Herpes Simplex Infection Infection in the first month of life caused by the Herpes simplex virus. Infection in the first month of life caused by the Herpes simplex virus. C99231 Neonatal Infectious Disorder C118464 Pediatric Adverse Events Terminology C C116600 Motor Deficit Motor Deficits Loss of movement function. Movement impairment. C110937 Musculoskeletal Finding C118464 Pediatric Adverse Events Terminology C C117193 Repetitive Behavior Repetitive Behaviors Recurring actions that are often non-purposeful. Recurring actions that are often non-purposeful. C5039 Motor Manifestations C118464 Pediatric Adverse Events Terminology C C118258 Thymic Damage Thymic Damage Anatomic injury or physiologic dysfunction of the thymus gland. Anatomic injury or physiologic dysfunction of the thymus gland. C36285 Endocrine System Finding C118464 Pediatric Adverse Events Terminology C C118720 Opsoclonus Opsoclonus A rapid, multivectorial, conjugate, involuntary eye movement, without an intersaccadic interval. A rapid, multivectoral, conjugate, involuntary eye movement, without an intersaccadic interval. C99208 Eye Finding C118464 Pediatric Adverse Events Terminology C C122426 Acquired Cytomegaloviral Infection Acquired Cytomegaloviral Infection An infection with the Cytomegalovirus that is not present from birth. An infection with the Cytomegalovirus that is not present from birth. C3439 Viral Infection C118464 Pediatric Adverse Events Terminology C C122710 Medical Device Failure Medical Device Failure A medical device that is no longer functioning. A medical device that is no longer functioning. C78254 Device Complication C118464 Pediatric Adverse Events Terminology C C30085 Muscle Contraction Muscle Contraction The process where thick (myosin) and thin (actin) filaments slide against each other to produce a shortening or tensing of the muscle cell or fiber. The process where thick (myosin) and thin (actin) filaments slide against each other to produce a shortening or tensing of the muscle cell or fiber. C100104 Sign or Symptom C118464 Pediatric Adverse Events Terminology C C50617 Intraocular Infection Intraocular Infection Infection within the eye. An infectious process within the eye. C26767 Eye Disorder C118464 Pediatric Adverse Events Terminology C C79552 Enophthalmos Enophthalmos Abnormal recession of the eyeball within the eye socket. The posterior displacement of the eye within the orbit. C99208 Eye Finding C118464 Pediatric Adverse Events Terminology 10014853 Enophthalmos C C84473 Atrial Septal Defect Atrial Septal Defect The presence of a defect (opening) in the septum that separates the two atria of the heart. It can be congenital or acquired. C84482 Congenital Septal Defect C118464 Pediatric Adverse Events Terminology 10003664 Atrial septal defect C C118676 Perinatal Mortality Perinatal Mortality Fetal or infant death during the period of time that includes the antepartum, intrapartum, and neonatal stages. Fetal or infant death during the period of time that includes the antepartum, Intrapartum, and neonatal stages. C90491 Pregnancy Outcome C118464 Pediatric Adverse Events Terminology 10076720 Perinatal death C C3408 Thrombocytopenia Thrombocytopenia Thrombocytopenic Disorder A laboratory test result indicating that there is an abnormally small number of platelets in the circulating blood. Abnormally low level of platelets in the blood. C26323 Hematologic Disorder C36292 Laboratory Test Result C118464 Pediatric Adverse Events Terminology 10043554 Thrombocytopenia