C C2869 Anemia Anemia A reduction in the number of red blood cells, the amount of hemoglobin, and/or the volume of packed red blood cells. Clinically, anemia represents a reduction in the oxygen-transporting capacity of a designated volume of blood, resulting from an imbalance between blood loss (through hemorrhage or hemolysis) and blood production. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability. Abnormally low level of hemoglobin in the blood. C26323 Hematologic Disorder C118464 Pediatric Adverse Events Terminology Anemia Has Synonym LLT 10002272 MedDRA C C3063 Graft Versus Host Disease Graft Versus Host Disease A reaction, which may be fatal, in an immunocompromised subject (host) who has received an antigenically incompatible tissue transplant (graft) from an immunocompetent donor. The reaction is secondary to the activation of the transplanted cells against those host tissues that express an antigen not expressed by the donor, and is seen most commonly following bone marrow transplantation; acute disease is seen after 5-40 days, and chronic disease occurs weeks to months after transplantation. A reaction, which may be fatal, in an immunocompromised subject (host) who has received an antigenically incompatible tissue transplant (graft) from an immunocompetent donor. The reaction is secondary to the activation of the transplanted cells against those host tissues that express an antigen not expressed by the donor, and is seen most commonly following stem cell transplantation; acute disease is seen after 5-40 days, and chronic disease occurs weeks to months after transplantation. C3507 Immune System Disorder C118464 Pediatric Adverse Events Terminology Graft versus host disease Has Synonym LLT 10018651 MedDRA A C26692 Factor I Deficiency Hypofibrinogenemia Factor I Deficiency|Fibrinogen Deficiency A blood coagulation disorder characterized by low levels of fibrinogen in the blood, resulting in bleeding. Abnormally low level of fibrinogen in the blood. C36292 Laboratory Test Result C118464 Pediatric Adverse Events Terminology Hypofibrinogenemia Has Synonym LLT 10020978 MedDRA D C98131 Hypofibrinogenemia Hypofibrinogenemia Factor I Deficiency|Fibrinogen Deficiency A blood coagulation disorder characterized by low levels of fibrinogen in the blood, resulting in bleeding. Abnormally low level of fibrinogen in the blood. C36292 Laboratory Test Result C118464 Pediatric Adverse Events Terminology Hypofibrinogenemia Has Synonym LLT 10020978 MedDRA