C C27146 Hemophilia A Hemophilia A Factor VIII Deficiency|Hereditary Factor VIII Deficiency Disease An inherited deficiency of coagulation factor VIII characterized by the tendency to spontaneous or exaggerated post-traumatic hemorrhage. Inherited as an X-linked recessive disease, hemophilia A is the most common hemophilia, occurring in approximately 1 in 10,000 male births. C3093 Hemophilia C99147 Neonatal Research Network Terminology