C	C4376	Renal Failure	Renal Failure Syndrome		Acute or chronic condition, characterized by the inability of the kidneys to adequately filter the blood substances, resulting in uremia and electrolyte imbalances. Acute renal failure is usually associated with oliguria or anuria, hyperkalemia, and pulmonary edema. Chronic renal failure is irreversible and requires hemodialysis.		C3149	Kidney Disease			C99147	Neonatal Research Network Terminology
C	C106273	ABO Hemolytic Disease of the Newborn	ABO Isoimmunization	Hemolytic Disease due to ABO Isoimmunization	A condition of the newborn characterized by the destruction of red blood cells initiated by the transmission of anti-A or anti-B antibodies from a mother to the child via the placenta against A or B antigens of the newborn's blood.		C101304	Hemolytic Disease of the Newborn			C99147	Neonatal Research Network Terminology
C	C90599	Bronchopulmonary Dysplasia	Bronchopulmonary Dysplasia		Chronic lung disease requiring treatment with oxygen for at least 28 days and with a spectrum of severity from mild to severe, that predominantly affects premature infants. While the radiologic pattern is typical in the closer to term patient, the pattern in the small preterm infant is very non-discrete and variable.		C97173	Congenital Abnormality of the Respiratory System			C99147	Neonatal Research Network Terminology
C	C84611	Canavan Disease	Canavan Disease	Spongy Degeneration of Central Nervous System	A disorder that belongs in the group of leukodystrophies. It is caused by mutations in the ASPA gene which is responsible for the production of the enzyme aspartoacylase. It is characterized by spongy degeneration of the white matter of the brain. Signs and symptoms appear in infancy and include mental retardation, loss of motor skills, abnormal muscle tone, feeding difficulties and a very large head.	Spongy degeneration of central nervous system, spongy degeneration of white matter a rare hereditary form of leukodystrophy of early onset in which widespread demyelination and vacuolation of cerebral white matter gives it a spongy appearance; there is mental retardation, megalocephaly, atony of neck muscles, limb spasticity, and blindness, with death in infancy.	C2934	Central Nervous System Disorder			C99147	Neonatal Research Network Terminology