A C101191 Acquired Bilateral Cataracts Acquired Bilateral Cataracts Cataracts in both eyes that result from the aging process, an injury, or as a manifestation of a systemic disorder. C98802 Acquired Cataract C90259 NICHD Pediatric Terminology A C103172 Congenital Bleeding Disorder Congenital Coagulation Defect Congenital Bleeding Defect A bleeding disorder that is diagnosed during childhood. the presenting symptom is excessive bleeding. C2902 Coagulation Defect C61234 Congenital Hematological Disorder C90259 NICHD Pediatric Terminology A C2881 Arrhythmia Cardiac Arrhythmia An electrocardiographic finding of any variation from the normal rate or rhythm (which may include the origin of the impulse and/or its subsequent propagation) in the heart. Cardiac Arrhythmias are heart-rhythm problems - they occur when the electrical impulses to the heart that coordinate heartbeats are not working properly, making the heart beat too fast/slow or inconsistently. C78245 Cardiac Conduction Disorder C90259 NICHD Pediatric Terminology A C3117 Hypertension Hypertensive Disorder Pathological increase in blood pressure; a repeatedly elevated blood pressure exceeding 140 over 90 mmHg. C2931 Cardiovascular Disorder C90259 NICHD Pediatric Terminology A C34348 Acrocephalosyndactyly Acrocephalosyndactyly A genetic disorder characterized by craniosynostosis and fusion of the fingers and toes. C98829 Autosomal Dominant Hereditary Disorder C89337 Congenital Abnormality of the Musculoskeletal System C90259 NICHD Pediatric Terminology A C34685 Hernia Hernia The protrusion of part of an organ or fibroadipose tissue through an abnormal opening. C36287 Deformity C90259 NICHD Pediatric Terminology A C61234 Congenital Abnormalities of Erythrocyte Differentiation or Function Congenital Hematological Disorder Inherited disorders involving abnormalities of red blood cell function, structure, or production. Some diseases in this group may be associated with bone marrow failure, neutropenia, and/or thrombocytopenia. C2849 Congenital Abnormality C26323 Hematological Disorder C90259 NICHD Pediatric Terminology A C98828 Small Intestine Atresia Atresia of Small Intestine A malformation characterized by the absence of a normal opening in a part of the small intestine. C97171 Congenital Abnormality of the Digestive System C90259 NICHD Pediatric Terminology C C100104 Sign or Symptom Signs or Symptoms Objective evidence of disease perceptible to the examining practitioner (sign) and subjective evidence of disease perceived by the patient (symptom). C3367 Clinical Finding|Finding C89506 NICHD Newborn Screening Terminology C C100104 Sign or Symptom Signs or Symptoms Objective evidence of disease perceptible to the examining practitioner (sign) and subjective evidence of disease perceived by the patient (symptom). C3367 Clinical Finding|Finding C90259 NICHD Pediatric Terminology C C12219 Anatomic Structure, System, or Substance Anatomic Structure or System A human biological structure, fluid or other substance; excludes single molecular entities. C89505 C90259 NICHD Pediatric Terminology C C12220 Lip Lip Fleshy fold which surrounds the opening of the mouth. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C12220 Lip Lip Fleshy fold which surrounds the opening of the mouth. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C12326 Undescended Testis Undescended Testis The failure of one or both testes of a male fetus to descend from the abdomen into the scrotum during the late part of pregnancy. If not surgically corrected in early childhood, males may be at increased risk for testicular cancer later in life. C103185 Congenital Abnormality of the Reproductive System C27019 Male Reproductive System Disorder C89506 NICHD Newborn Screening Terminology C C12326 Undescended Testis Undescended Testis The failure of one or both testes of a male fetus to descend from the abdomen into the scrotum during the late part of pregnancy. If not surgically corrected in early childhood, males may be at increased risk for testicular cancer later in life. C103185 Congenital Abnormality of the Reproductive System C27019 Male Reproductive System Disorder C90259 NICHD Pediatric Terminology C C12390 Rectum Rectum The terminal portion of the gastrointestinal tract, extending from the rectosigmoid junction to the anal canal. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C12390 Rectum Rectum The terminal portion of the gastrointestinal tract, extending from the rectosigmoid junction to the anal canal. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C12394 Ear Ear A sense organ needed for the detection of sound and for establishing balance. The outer ear consists of the auricle, the ear canal as well as the tympanic membrane. The middle ear is made up of an air-filled cavity behind the tympanic membrane that contains the ossicles (malleus, incus and stapes). The inner ear is made up of the cochlea needed for hearing and the vestibular apparatus required for balance. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C12394 Ear Ear A sense organ needed for the detection of sound and for establishing balance. The outer ear consists of the auricle, the ear canal as well as the tympanic membrane. The middle ear is made up of an air-filled cavity behind the tympanic membrane that contains the ossicles (malleus, incus and stapes). The inner ear is made up of the cochlea needed for hearing and the vestibular apparatus required for balance. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C12401 Eye Eye The organ of sight or vision. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C12401 Eye Eye The organ of sight or vision. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C12419 Head Head The anterior and superior part of a human bearing the mouth, the brain and sensory organs. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C12419 Head Head The anterior and superior part of a human bearing the mouth, the brain and sensory organs. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C12421 Oral Cavity Oral Cavity The cavity located at the upper end of the alimentary canal, behind the teeth and gums that is bounded on the outside by the lips, above by the hard and soft palates and below by the tongue. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C12421 Oral Cavity Oral Cavity The cavity located at the upper end of the alimentary canal, behind the teeth and gums that is bounded on the outside by the lips, above by the hard and soft palates and below by the tongue. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C12664 Abdominal Cavity Abdomen The portion of the body that lies between the thorax and the pelvis. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C12664 Abdominal Cavity Abdomen The portion of the body that lies between the thorax and the pelvis. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C12756 Nose Nose A structure of special sense serving as an organ of the sense of smell and as an entrance to the respiratory tract. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C12756 Nose Nose A structure of special sense serving as an organ of the sense of smell and as an entrance to the respiratory tract. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C12799 Thorax Thorax The division of the body lying between the neck and the abdomen. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C12799 Thorax Thorax The division of the body lying between the neck and the abdomen. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C12998 Vertebral Column Vertebral Column A series of bones, muscles, tendons, and other tissues reaching from the base of the skull to the tailbone. The vertebral column forms the axis of the skeleton and encloses as well as protects the spinal cord and the fluid surrounding the spinal cord. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C12998 Vertebral Column Vertebral Column A series of bones, muscles, tendons, and other tissues reaching from the base of the skull to the tailbone. The vertebral column forms the axis of the skeleton and encloses as well as protects the spinal cord and the fluid surrounding the spinal cord. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C13063 Neck Neck The region that connects the head to the rest of the body. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C13063 Neck Neck The region that connects the head to the rest of the body. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C14250 Organism Organism A living entity. C89505 C90259 NICHD Pediatric Terminology C C15181 Anesthesia Procedure Anesthesia Procedure Treatment with a pharmacological substance that produces a loss of feeling. C25218 Intervention or Procedure|Procedure C89506 NICHD Newborn Screening Terminology C C15181 Anesthesia Procedure Anesthesia Procedure Treatment with a pharmacological substance that produces a loss of feeling. C25218 Intervention or Procedure|Procedure C90259 NICHD Pediatric Terminology C C15181 Anesthesia Procedure Anesthesia Procedure Treatment with a pharmacological substance that produces a loss of feeling. C25218 Intervention or Procedure|Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C15329 Surgical Procedure Surgical Procedure A diagnostic or treatment procedure performed by manual and/or instrumental means, often involving an incision and the removal or replacement of a diseased organ or tissue; of or relating to or involving or used in surgery or requiring or amenable to treatment by surgery. C25218 Intervention or Procedure|Procedure C90259 NICHD Pediatric Terminology C C15384 Surgical Incision Surgical Incision An intentional cut made to an individual's body with the intent of performing a diagnostic or therapeutic intervention. C25218 Intervention or Procedure|Procedure C90259 NICHD Pediatric Terminology C C15384 Surgical Incision Surgical Incision An intentional cut made to an individual's body with the intent of performing a diagnostic or therapeutic intervention. C25218 Intervention or Procedure|Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C15843 Preventive Intervention Preventive Intervention Therapeutic, nutritional, environmental, social and or behavioral interventions at the societal, community, organizational or individual levels to reduce, modify or stop the course of a disease. C25218 Intervention or Procedure|Procedure C90259 NICHD Pediatric Terminology C C16205 Healthcare Activity Healthcare Activity The actions of prevention, treatment, and management of illness and the preservation of mental and physical well-being through the services offered by the medical and allied health professions. C89505 C90259 NICHD Pediatric Terminology C C16205 Healthcare Activity Healthcare Activity The actions of prevention, treatment, and management of illness and the preservation of mental and physical well-being through the services offered by the medical and allied health professions. C89505 C92712 NICHD Pregnancy & Childbirth Terminology C C16847 Technique Technique A practiced and regimented skill or series of actions. C25218 Intervention or Procedure|Procedure C90259 NICHD Pediatric Terminology C C18020 Diagnostic Procedure Diagnostic Procedure Methods, procedures, and tests performed to diagnose disease, disordered function, or disability. C25218 Intervention or Procedure|Procedure C90259 NICHD Pediatric Terminology C C19988 Organismal Process Organismal Process A biologic function, activity, or process involving either specialized organ functions, individual organs, organ systems, body parts, or whole organisms. C89505 C90259 NICHD Pediatric Terminology C C20189 Property or Attribute Property or Attribute A distinguishing quality or prominent aspect of a person, object, action, process, or substance. C89505 C90259 NICHD Pediatric Terminology C C20989 Physical Examination Physical Examination A systemic evaluation of the body and it's functions using visual inspection, palpation, percussion and auscultation. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment. C25214 Evaluation Procedure C89506 NICHD Newborn Screening Terminology C C20989 Physical Examination Physical Examination A systemic evaluation of the body and it's functions using visual inspection, palpation, percussion and auscultation. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment. C25214 Evaluation Procedure C90259 NICHD Pediatric Terminology C C25177 Genitalia Genitalia The external sex organs. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C25177 Genitalia Genitalia The external sex organs. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C25190 Person Person A human being. C89505 C89506 NICHD Newborn Screening Terminology C C25190 Person Person A human being. C89505 C90259 NICHD Pediatric Terminology C C25203 Shoulder Shoulder The region of the body between the neck and the upper arm. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C25203 Shoulder Shoulder The region of the body between the neck and the upper arm. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C25214 Evaluation Evaluation Procedure Systematic, objective appraisal of the significance, effectiveness, and impact of activities or condition according to specified objectives and criteria. C25218 Intervention or Procedure|Procedure C90259 NICHD Pediatric Terminology C C25214 Evaluation Evaluation Procedure Systematic, objective appraisal of the significance, effectiveness, and impact of activities or condition according to specified objectives and criteria. C25218 Intervention or Procedure|Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C25215 Karyotype Karyotype The appearance of the chromosomal makeup of a somatic cell in an individual or species, including the number and arrangement and size and structure of the chromosomes. C15709 Genetic Test|Genetic Testing C89506 NICHD Newborn Screening Terminology C C25215 Karyotype Karyotype The appearance of the chromosomal makeup of a somatic cell in an individual or species, including the number and arrangement and size and structure of the chromosomes. C15709 Genetic Test|Genetic Testing C90259 NICHD Pediatric Terminology C C25294 Laboratory Procedure Laboratory Procedure Any procedure that involves testing or manipulating a sample of blood, urine, or other body substance in a laboratory setting. C18020 Diagnostic Procedure C89506 NICHD Newborn Screening Terminology C C25294 Laboratory Procedure Laboratory Procedure Any procedure that involves testing or manipulating a sample of blood, urine, or other body substance in a laboratory setting. C18020 Diagnostic Procedure C90259 NICHD Pediatric Terminology C C26323 Hematologic and Lymphocytic Disorder Hematological Disorder A neoplastic or non-neoplastic disorder that affects the production and proliferation of the hematopoietic cells including lymphoid cells, the synthesis of hemoglobin, and/or the mechanisms of coagulation. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C26685 Premature Separation of Placenta Placental Abruption The separation of the placenta from the maternal uterine attachment when it occurs after the twentieth week of the pregnancy. C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C26685 Premature Separation of Placenta Placental Abruption The separation of the placenta from the maternal uterine attachment when it occurs after the twentieth week of the pregnancy. C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C26720 Chorioamnionitis Chorioamnionitis Inflammation of the fetal sac membranes. C93210 Inflammatory Disorder C35169 Pregnancy Disorder C90259 NICHD Pediatric Terminology C C26720 Chorioamnionitis Chorioamnionitis Inflammation of the fetal sac membranes. C93210 Inflammatory Disorder C35169 Pregnancy Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C26726 Infectious Disorder Infectious Disease A disorder resulting from the presence and activity of a microbial, viral, or parasitic agent. It can be transmitted by direct or indirect contact. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C26726 Infectious Disorder Infectious Disease A disorder resulting from the presence and activity of a microbial, viral, or parasitic agent. It can be transmitted by direct or indirect contact. C2991 Disease or Disorder|Disease C96388 NICHD Childhood Immunization Terminology C C26734 Congenital Hypothyroidism Congenital Hypothyroidism A deficiency of thyroid hormone present at birth. The etiology can be genetic or environmental, or a combination of both; treatment is based on severity and causality. C34816 Congenital Metabolic Disorder|Inborn Error of Metabolism C89506 NICHD Newborn Screening Terminology C C26734 Congenital Hypothyroidism Congenital Hypothyroidism A deficiency of thyroid hormone present at birth. The etiology can be genetic or environmental, or a combination of both; treatment is based on severity and causality. C34816 Congenital Metabolic Disorder|Inborn Error of Metabolism C90259 NICHD Pediatric Terminology C C26828 Meningitis Meningitis A disorder characterized by acute inflammation of the meninges of the brain and/or spinal cord. C27582 Central Nervous System Infectious Disease C93210 Inflammatory Disorder C90259 NICHD Pediatric Terminology C C26828 Meningitis Meningitis A disorder characterized by acute inflammation of the meninges of the brain and/or spinal cord. C27582 Central Nervous System Infectious Disease C93210 Inflammatory Disorder C96388 NICHD Childhood Immunization Terminology C C26835 Nervous System Disorder Neurologic Disorder A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C26835 Nervous System Disorder Neurologic Disorder A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves. C2991 Disease or Disorder|Disease C97150 NICHD Neurological Development Terminology C C26858 Placenta Previa Placenta Previa A condition in which the placenta is implanted in the lower part of the uterus. --2003 C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C26858 Placenta Previa Placenta Previa A condition in which the placenta is implanted in the lower part of the uterus. --2003 C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C26871 Respiratory Disorder Respiratory System Disorder A non-neoplastic or neoplastic disorder that affects the tracheobronchial tree and/or the lung parenchyma. Representative examples include infections, carcinomas, and lymphomas. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C27560 Neonatal Respiratory Distress Syndrome Neonatal Respiratory Distress Syndrome A condition of the newborn marked by dyspnea with cyanosis, most frequently occurring in premature infants, children of diabetic mothers and infants delivered by cesarean section, and sometimes with no predisposing cause. C97173 Congenital Abnormality of the Respiratory System C99232 Neonatal Respiratory System Disorder C90259 NICHD Pediatric Terminology C C27560 Neonatal Respiratory Distress Syndrome Neonatal Respiratory Distress Syndrome A condition of the newborn marked by dyspnea with cyanosis, most frequently occurring in premature infants, children of diabetic mothers and infants delivered by cesarean section, and sometimes with no predisposing cause. C97173 Congenital Abnormality of the Respiratory System C99232 Neonatal Respiratory System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C27574 Connective and Soft Tissue Disorder Musculoskeletal System Disorder Any deviation from the normal structure or function of the musculoskeletal or connective tissue that is manifested by a characteristic set of symptoms and signs. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C2931 Cardiovascular Disorder Cardiovascular Disorder A non-neoplastic or neoplastic disorder affecting the heart or the vessels (arteries, veins and lymph vessels). Representative examples of non-neoplastic cardiovascular disorders are endocarditis and hypertension. Representative examples of neoplastic cardiovascular disorders are endocardial myxoma and angiosarcoma. C2991 Disease or Disorder|Disease C89506 NICHD Newborn Screening Terminology C C2931 Cardiovascular Disorder Cardiovascular Disorder A non-neoplastic or neoplastic disorder affecting the heart or the vessels (arteries, veins and lymph vessels). Representative examples of non-neoplastic cardiovascular disorders are endocarditis and hypertension. Representative examples of neoplastic cardiovascular disorders are endocardial myxoma and angiosarcoma. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C2934 Central Nervous System Disorder Central Nervous System Disorder A non-neoplastic or neoplastic disorder which affects the brain and/or spinal cord. C26835 Nervous System Disorder|Neurologic Disorder C90259 NICHD Pediatric Terminology C C2934 Central Nervous System Disorder Central Nervous System Disorder A non-neoplastic or neoplastic disorder which affects the brain and/or spinal cord. C26835 Nervous System Disorder|Neurologic Disorder C97150 NICHD Neurological Development Terminology C C2962 Seizure Seizure Sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin. C87124 Central Nervous System (CNS) Symptom|Central Nervous System Signs and Symptoms C89506 NICHD Newborn Screening Terminology C C2962 Seizure Seizure Sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin. C87124 Central Nervous System (CNS) Symptom|Central Nervous System Signs and Symptoms C90259 NICHD Pediatric Terminology C C2962 Seizure Seizure Sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin. C87124 Central Nervous System (CNS) Symptom|Central Nervous System Signs and Symptoms C97150 NICHD Neurological Development Terminology C C2978 Cyst Cyst A sac-like closed membranous structure that may be empty or contain fluid or amorphous material. C3367 Clinical Finding|Finding C90259 NICHD Pediatric Terminology C C2990 Gastrointestinal Disorder Gastrointestinal Disorder A non-neoplastic or neoplastic disorder that affects the gastrointestinal tract, anus, liver, biliary system, and pancreas. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C2991 Disease or Disorder Disease or Disorder Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function. C89505 C90259 NICHD Pediatric Terminology C C3009 Endocrine Disorder Endocrine System Disorder Any deviation from the normal structure or function of the endocrine system that is manifested by a characteristic set of symptoms and signs. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C3038 Fever Fever The elevation of the body's temperature above the upper limit of normal, usually taken as 37.7 degrees C. C50589 Hyperthermia C90259 NICHD Pediatric Terminology C C3038 Fever Fever The elevation of the body's temperature above the upper limit of normal, usually taken as 37.7 degrees C. C50589 Hyperthermia C96388 NICHD Childhood Immunization Terminology C C307 Biological Agent Biologic Agent Biotechnology-derived pharmaceutical agents made from living organisms or their products. Includes recombinant proteins, monoclonal antibodies, and nucleic acids. C1909 Pharmacologic Substance C90259 NICHD Pediatric Terminology C C3085 Hemangioma Hemangioma A benign localized vascular neoplasm usually occurring in infancy and childhood. It is characterized by the formation of capillary-sized or cavernous vascular channels. The majority of cases are congenital. C3262 Neoplasm|Neoplastic Disease C89506 NICHD Newborn Screening Terminology C C3085 Hemangioma Hemangioma A benign localized vascular neoplasm usually occurring in infancy and childhood. It is characterized by the formation of capillary-sized or cavernous vascular channels. The majority of cases are congenital. C3262 Neoplasm|Neoplastic Disease C90259 NICHD Pediatric Terminology C C3096 Hepatitis A Infection Hepatitis A Acute inflammation of the liver caused by the hepatitis A virus. It is highly contagious and usually contracted through close contact with an infected individual or their feces, contaminated food or water. C93210 Inflammatory Disorder C3439 Viral Disease C90259 NICHD Pediatric Terminology C C3096 Hepatitis A Infection Hepatitis A Acute inflammation of the liver caused by the hepatitis A virus. It is highly contagious and usually contracted through close contact with an infected individual or their feces, contaminated food or water. C93210 Inflammatory Disorder C3439 Viral Disease C96388 NICHD Childhood Immunization Terminology C C3097 Hepatitis B Infection Hepatitis B A viral infection caused by the hepatitis B virus. C93210 Inflammatory Disorder C3439 Viral Disease C90259 NICHD Pediatric Terminology C C3097 Hepatitis B Infection Hepatitis B A viral infection caused by the hepatitis B virus. C93210 Inflammatory Disorder C3439 Viral Disease C96388 NICHD Childhood Immunization Terminology C C3101 Genetic Disorder Genetic Disorder Genetic Diseases are diseases in which inherited genes predispose to increased risk. The genetic disorders associated with cancer often result from an alteration or mutation in a single gene. The diseases range from rare dominant cancer family syndrome to familial tendencies in which low-penetrance genes may interact with other genes or environmental factors to induce cancer. Research may involve clinical, epidemiologic, and laboratory studies of persons, families, and populations at high risk of these disorders. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C32078 Ankle Joint Ankle Joint A gliding joint between the distal ends of the tibia and fibula and the proximal end of the talus. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C32078 Ankle Joint Ankle Joint A gliding joint between the distal ends of the tibia and fibula and the proximal end of the talus. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C32141 Arm Arm The portion of the upper extremity between the shoulder and the elbow. For clinical purposes this term is also used to refer to the whole superior limb. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C32141 Arm Arm The portion of the upper extremity between the shoulder and the elbow. For clinical purposes this term is also used to refer to the whole superior limb. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C32497 Elbow Joint Elbow Joint A type of hinge joint located between the forearm and upper arm. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C32497 Elbow Joint Elbow Joint A type of hinge joint located between the forearm and upper arm. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C3262 Neoplasm Neoplasm A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C32622 Foot Foot The structure found below the ankle joint required for locomotion. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C32622 Foot Foot The structure found below the ankle joint required for locomotion. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C32712 Hand Hand The distal portion of the upper extremity. It consists of the carpus, metacarpus, and digits. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C32712 Hand Hand The distal portion of the upper extremity. It consists of the carpus, metacarpus, and digits. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C32856 Internal Nare Internal Nare The inner portion of the nostrils of the nose. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C32856 Internal Nare Internal Nare The inner portion of the nostrils of the nose. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C32884 Ischium Ischium The most posterior and ventral bone making up the pelvis. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C32884 Ischium Ischium The most posterior and ventral bone making up the pelvis. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C32898 Knee Joint Knee Joint A joint connecting the lower part of the femur with the upper part of the tibia. The lower part of the femur and the upper part of the tibia are attached to each other by ligaments. Other structures of the knee joint include the upper part of the fibula, located below and parallel to the tibia, and the patella which moves as the knee bends. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C32898 Knee Joint Knee Joint A joint connecting the lower part of the femur with the upper part of the tibia. The lower part of the femur and the upper part of the tibia are attached to each other by ligaments. Other structures of the knee joint include the upper part of the fibula, located below and parallel to the tibia, and the patella which moves as the knee bends. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C32974 Leg Leg One of the two lower extremities in humans used for locomotion and support. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C32974 Leg Leg One of the two lower extremities in humans used for locomotion and support. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C3333 Pneumonia Pneumonia An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, due to infections (viruses, fungi, mycoplasma, or bacteria), treatment (e.g. radiation), or exposure (inhalation) to chemicals. Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness. C3198 Lung Disorder C90259 NICHD Pediatric Terminology C C3333 Pneumonia Pneumonia An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, due to infections (viruses, fungi, mycoplasma, or bacteria), treatment (e.g. radiation), or exposure (inhalation) to chemicals. Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness. C3198 Lung Disorder C96388 NICHD Childhood Immunization Terminology C C3367 Finding Finding Clinical, laboratory or molecular evidence, or absence of evidence of disease. C89505 C89506 NICHD Newborn Screening Terminology C C3367 Finding Finding Clinical, laboratory or molecular evidence, or absence of evidence of disease. C89505 C90259 NICHD Pediatric Terminology C C3371 Skin Disorder Integumentary System Disorder Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C3376 Sleep Disorder Sleep Disorder A change from the patient's baseline sleeping pattern, either an increase or a decrease in the number of hours slept. This can also refer to alterations in the stages of sleep. C26835 Nervous System Disorder|Neurologic Disorder C90259 NICHD Pediatric Terminology C C33788 Toe Toe One of the terminal digits of the foot. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C33788 Toe Toe One of the terminal digits of the foot. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C3430 Urinary System Disorder Urinary System Disorder Disorders of any part of the urologic system. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C3430 Urinary System Disorder Urinary System Disorder Disorders of any part of the urologic system. C2991 Disease or Disorder|Disease C92712 NICHD Pregnancy & Childbirth Terminology C C34376 Hemolytic Anemia Hemolytic Anemia Anemia resulting from the premature destruction of the peripheral blood red cells. It may be congenital or it may be caused by infections, medications, or malignancies. C2869 Anemia C90259 NICHD Pediatric Terminology C C34376 Hemolytic Anemia Hemolytic Anemia Anemia resulting from the premature destruction of the peripheral blood red cells. It may be congenital or it may be caused by infections, medications, or malignancies. C2869 Anemia C92712 NICHD Pregnancy & Childbirth Terminology C C34383 Sickle Cell Disease Sickle Cell Disease A blood disorder characterized by the appearance of sickle-shaped red blood cells and anemia. C3092 Hemoglobinopathy C89506 NICHD Newborn Screening Terminology C C34383 Sickle Cell Disease Sickle Cell Disease A blood disorder characterized by the appearance of sickle-shaped red blood cells and anemia. C3092 Hemoglobinopathy C90259 NICHD Pediatric Terminology C C34460 Cerebral Palsy Cerebral Palsy A group of disorders affecting the development of movement and posture, often accompanied by disturbances of sensation, perception, cognition, and behavior. It results from damage to the fetal or infant brain. C26835 Nervous System Disorder|Neurologic Disorder C89328 Pediatric Disease or Disorder C90259 NICHD Pediatric Terminology C C34460 Cerebral Palsy Cerebral Palsy A group of disorders affecting the development of movement and posture, often accompanied by disturbances of sensation, perception, cognition, and behavior. It results from damage to the fetal or infant brain. C26835 Nervous System Disorder|Neurologic Disorder C89328 Pediatric Disease or Disorder C97150 NICHD Neurological Development Terminology C C34491 Clubbing of Fingers Clubbing of Fingers An abnormal enlargement of the terminal phalanges accompanied by increased length-wise curvature of the nails, giving the digits a club-like appearance. Clubbing has been noted with a wide variety of conditions, including pulmonary and cardiac diseases, liver disorders, and disorders of the gastrointestinal tract. C100104 Signs or Symptoms C89506 NICHD Newborn Screening Terminology C C34491 Clubbing of Fingers Clubbing of Fingers An abnormal enlargement of the terminal phalanges accompanied by increased length-wise curvature of the nails, giving the digits a club-like appearance. Clubbing has been noted with a wide variety of conditions, including pulmonary and cardiac diseases, liver disorders, and disorders of the gastrointestinal tract. C100104 Signs or Symptoms C90259 NICHD Pediatric Terminology C C34527 Demyelinating Disorder Demyelinating Disorder A broad group of disorders that affect the myelin sheaths that cover the neurons. Myelin sheathes cover neuronal axons in the central and peripheral nervous system and function to increase travelling impulse speeds. Disruption of this sheath impairs neuronal transmission and can result in disorders such as multiple sclerosis and Guillain-Barre syndrome, among others. C26835 Nervous System Disorder|Neurologic Disorder C90259 NICHD Pediatric Terminology C C34527 Demyelinating Disorder Demyelinating Disorder A broad group of disorders that affect the myelin sheaths that cover the neurons. Myelin sheathes cover neuronal axons in the central and peripheral nervous system and function to increase travelling impulse speeds. Disruption of this sheath impairs neuronal transmission and can result in disorders such as multiple sclerosis and Guillain-Barre syndrome, among others. C26835 Nervous System Disorder|Neurologic Disorder C97150 NICHD Neurological Development Terminology C C34632 Gastroenteritis Gastroenteritis An inflammatory disorder that affects the upper and lower gastrointestinal tract. Most commonly, this is attributed to viruses; however bacteria, parasites or adverse reactions can also be the culprit. Symptoms include acute diarrhea and vomiting. C2990 Digestive System Disorder|Gastrointestinal Disorder C93210 Inflammatory Disorder C90259 NICHD Pediatric Terminology C C34675 Hemoglobin C Disease Hemoglobin C Disease A blood disorder characterized by the appearance of sickle-shaped red blood cells and anemia. This disorder is caused by a specific mutation in the beta-globin HBB gene, whereby a lysine is substituted for a glutamic acid at the sixth amino acid in the protein. C3092 Hemoglobinopathy C89506 NICHD Newborn Screening Terminology C C34675 Hemoglobin C Disease Hemoglobin C Disease A blood disorder characterized by the appearance of sickle-shaped red blood cells and anemia. This disorder is caused by a specific mutation in the beta-globin HBB gene, whereby a lysine is substituted for a glutamic acid at the sixth amino acid in the protein. C3092 Hemoglobinopathy C90259 NICHD Pediatric Terminology C C34687 Diaphragmatic Hernia Diaphragmatic Hernia A congenital or acquired weakness or opening in the diaphragm which allows abdominal contents to protrude into the chest cavity; congenital diaphragmatic hernias are caused when the embryonic diaphragm fails to fuse. C34685 Hernia C89506 NICHD Newborn Screening Terminology C C34687 Diaphragmatic Hernia Diaphragmatic Hernia A congenital or acquired weakness or opening in the diaphragm which allows abdominal contents to protrude into the chest cavity; congenital diaphragmatic hernias are caused when the embryonic diaphragm fails to fuse. C34685 Hernia C90259 NICHD Pediatric Terminology C C34816 Congenital Metabolic Disorder Congenital Metabolic Disorder A group of disorders present at birth that involve genetic defects leading to disturbances in carbohydrate, lipid, lysosomal storage or amino acid metabolism in the body. C3235 Metabolic Disease C97151 Congenital Systemic Disorder C89506 NICHD Newborn Screening Terminology C C34816 Congenital Metabolic Disorder Congenital Metabolic Disorder A group of disorders present at birth that involve genetic defects leading to disturbances in carbohydrate, lipid, lysosomal storage or amino acid metabolism in the body. C3235 Metabolic Disease C97151 Congenital Systemic Disorder C90259 NICHD Pediatric Terminology C C34941 Pregnancy Complication Pregnancy Complication The co-occurrence of pregnancy and a disease. The disease may precede or follow conception and it may or may not have a deleterious effect on the pregnant woman or fetus. C2959 Complication C89506 NICHD Newborn Screening Terminology C C34941 Pregnancy Complication Pregnancy Complication The co-occurrence of pregnancy and a disease. The disease may precede or follow conception and it may or may not have a deleterious effect on the pregnant woman or fetus. C2959 Complication C90259 NICHD Pediatric Terminology C C34942 Gestational Diabetes Mellitus Gestational Diabetes Diabetes that develops during pregnancy. It usually resolves after delivery. C34941 Complication Related to Pregnancy|Pregnancy Complication C35169 Pregnancy Disorder C90259 NICHD Pediatric Terminology C C34942 Gestational Diabetes Mellitus Gestational Diabetes Diabetes that develops during pregnancy. It usually resolves after delivery. C34941 Complication Related to Pregnancy|Pregnancy Complication C35169 Pregnancy Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C34943 Toxemia of Pregnancy Toxemia A pregnancy induced hypertensive state that occurs after 20 weeks of gestation characterized by an increase in blood pressure, along with body swelling and proteinuria. C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C34943 Toxemia of Pregnancy Toxemia A pregnancy induced hypertensive state that occurs after 20 weeks of gestation characterized by an increase in blood pressure, along with body swelling and proteinuria. C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C34965 Pyelonephritis Pyelonephritis An acute or chronic inflammatory process affecting the kidney. It is caused by bacteria and in most cases it is the result of a urinary tract infection. Signs and symptoms include fever, chills, flank pain, painful and frequent urination, cloudy or bloody urine, and confusion. C2890 Bacterial Disease C93210 Inflammatory Disorder C90259 NICHD Pediatric Terminology C C34965 Pyelonephritis Pyelonephritis An acute or chronic inflammatory process affecting the kidney. It is caused by bacteria and in most cases it is the result of a urinary tract infection. Signs and symptoms include fever, chills, flank pain, painful and frequent urination, cloudy or bloody urine, and confusion. C2890 Bacterial Disease C93210 Inflammatory Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C34982 Retinopathy of Prematurity Retinopathy of Prematurity A bilateral retinopathy characterized by neovascularization, scarring, retinal detachment, and eventually blindness. It may be mild or severe. It occurs in babies born prematurely. Causes include oxygen toxicity and hypoxia. C35729 Congenital Abnormality of the Circulatory System C97172 Congenital Abnormality of the Nervous System C90259 NICHD Pediatric Terminology C C35040 Strabismus Strabismus Strabismus is the intermittent or constant misalignment of an eye so that its line of vision is not pointed at the same object as the other eye. Strabismus is caused by an imbalance in the extraocular muscles which control the positioning of the eyes. Strabismus is normal in newborns but should resolve by the time the baby is 6 months old. In older children with strabismus, the brain may learn to ignore the input from one eye, and this may lead to amblyopia, a potentially permanent decrease in vision in that eye if not corrected. C35126 Vision Disorder|Visual System Disorder C89506 NICHD Newborn Screening Terminology C C35040 Strabismus Strabismus Strabismus is the intermittent or constant misalignment of an eye so that its line of vision is not pointed at the same object as the other eye. Strabismus is caused by an imbalance in the extraocular muscles which control the positioning of the eyes. Strabismus is normal in newborns but should resolve by the time the baby is 6 months old. In older children with strabismus, the brain may learn to ignore the input from one eye, and this may lead to amblyopia, a potentially permanent decrease in vision in that eye if not corrected. C35126 Vision Disorder|Visual System Disorder C90259 NICHD Pediatric Terminology C C3507 Immune System Disorder Immunolymphatic System Disorder A disorder resulting from an abnormality in the immune system. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C35275 Visual Cortex Disorder Visual Cortex Disorder Cortical Visual Impairment A vision disorder that results from damage of the part of the cerebral cortex that is involved in the processing of visual information. C35126 Vision Disorder|Visual System Disorder C90259 NICHD Pediatric Terminology C C35275 Visual Cortex Disorder Visual Cortex Disorder Cortical Visual Impairment A vision disorder that results from damage of the part of the cerebral cortex that is involved in the processing of visual information. C35126 Vision Disorder|Visual System Disorder C97150 NICHD Neurological Development Terminology C C35470 Behavior-Related Disorder Behavioral Disorder A specific behavioral problem that occurs in persistent patterns and characteristic clusters and that causes clinically significant impairment. C96413 Brain Disorder C90259 NICHD Pediatric Terminology C C35470 Behavior-Related Disorder Behavioral Disorder A specific behavioral problem that occurs in persistent patterns and characteristic clusters and that causes clinically significant impairment. C96413 Brain Disorder C97150 NICHD Neurological Development Terminology C C35550 Acute Poliomyelitis Poliomyelitis Polio An acute infectious disorder that affects the nervous system. It is caused by the poliovirus. The virus spreads by direct contact, and can be prevented by prophylaxis with the polio vaccine. C93210 Inflammatory Disorder C96411 Childhood Viral Disease C90259 NICHD Pediatric Terminology C C35550 Acute Poliomyelitis Poliomyelitis Polio An acute infectious disorder that affects the nervous system. It is caused by the poliovirus. The virus spreads by direct contact, and can be prevented by prophylaxis with the polio vaccine. C93210 Inflammatory Disorder C96411 Childhood Viral Disease C96388 NICHD Childhood Immunization Terminology C C35729 Congenital Cardiovascular Abnormality Congenital Abnormality of the Circulatory System A heart or vascular abnormality which is inborn or present at birth. C2931 Cardiovascular Disorder C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology C C36284 Reproductive System Finding Reproductive System Finding Symptoms, physical examination results, and/or laboratory test results related to the reproductive system. C3367 Clinical Finding|Finding C90259 NICHD Pediatric Terminology C C36284 Reproductive System Finding Reproductive System Finding Symptoms, physical examination results, and/or laboratory test results related to the reproductive system. C3367 Clinical Finding|Finding C92712 NICHD Pregnancy & Childbirth Terminology C C36292 Laboratory Test Result Laboratory Test Result The outcome of a laboratory test. C77140 Clinical Test Result|Evaluation Finding C89506 NICHD Newborn Screening Terminology C C36292 Laboratory Test Result Laboratory Test Result The outcome of a laboratory test. C77140 Clinical Test Result|Evaluation Finding C90259 NICHD Pediatric Terminology C C3724 Cystic Hygroma Cystic Hygroma Cystic Lymphangioma A benign lymphatic neoplasm usually arising from the neck and characterized by cystic dilation of the lymphatic vessels. C2978 Cyst C3262 Neoplasm|Neoplastic Disease C89506 NICHD Newborn Screening Terminology C C3724 Cystic Hygroma Cystic Hygroma Cystic Lymphangioma A benign lymphatic neoplasm usually arising from the neck and characterized by cystic dilation of the lymphatic vessels. C2978 Cyst C3262 Neoplasm|Neoplastic Disease C90259 NICHD Pediatric Terminology C C3724 Cystic Hygroma Cystic Hygroma Cystic Lymphangioma A benign lymphatic neoplasm usually arising from the neck and characterized by cystic dilation of the lymphatic vessels. C2978 Cyst C3262 Neoplasm|Neoplastic Disease C96388 NICHD Childhood Immunization Terminology C C3782 Cervical Intraepithelial Neoplasia Cervical Intraepithelial Neoplasia Squamous or glandular intraepithelial neoplasia that affects the cervical mucosal epithelium. There is no evidence of stromal invasion. According to the degree of cellular atypia and the associated architectural changes, it is classified as low or high grade. C3262 Neoplasm|Neoplastic Disease C90259 NICHD Pediatric Terminology C C3782 Cervical Intraepithelial Neoplasia Cervical Intraepithelial Neoplasia Squamous or glandular intraepithelial neoplasia that affects the cervical mucosal epithelium. There is no evidence of stromal invasion. According to the degree of cellular atypia and the associated architectural changes, it is classified as low or high grade. C3262 Neoplasm|Neoplastic Disease C96388 NICHD Childhood Immunization Terminology C C37928 Confusion Confusion A mental state characterized by a lack of clear and orderly thought and behavior. C87124 Central Nervous System (CNS) Symptom|Central Nervous System Signs and Symptoms C90259 NICHD Pediatric Terminology C C37928 Confusion Confusion A mental state characterized by a lack of clear and orderly thought and behavior. C87124 Central Nervous System (CNS) Symptom|Central Nervous System Signs and Symptoms C96388 NICHD Childhood Immunization Terminology C C3890 Hypoxia Hypoxia A decrease in the amount of oxygen in the body. Symptoms range from mild (impaired judgment, memory loss, impaired motor coordination) to severe (seizures and coma). C9229 Systemic Disorder C89506 NICHD Newborn Screening Terminology C C3890 Hypoxia Hypoxia A decrease in the amount of oxygen in the body. Symptoms range from mild (impaired judgment, memory loss, impaired motor coordination) to severe (seizures and coma). C9229 Systemic Disorder C90259 NICHD Pediatric Terminology C C42767 Vaginal Diaphragm Vaginal Diaphragm A medical contraceptive device of soft flexible material, usually of thin rubber, that is designed to cover the cervix uteri prior to sexual intercourse to prevent the entry of spermatozoa. To enhance efficacy, a spermicidal agent is often placed within the device. Antimicrobial agent(s) can also be used to prevent sexually transmitted diseases. Efficacy of vaginal diaphragm against infections is very limited. A contraceptive device made of soft flexible material, usually of thin rubber, that is designed to cover the cervix uteri prior to sexual intercourse to prevent the entry of spermatozoa. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C C42767 Vaginal Diaphragm Vaginal Diaphragm A medical contraceptive device of soft flexible material, usually of thin rubber, that is designed to cover the cervix uteri prior to sexual intercourse to prevent the entry of spermatozoa. To enhance efficacy, a spermicidal agent is often placed within the device. Antimicrobial agent(s) can also be used to prevent sexually transmitted diseases. Efficacy of vaginal diaphragm against infections is very limited. A contraceptive device made of soft flexible material, usually of thin rubber, that is designed to cover the cervix uteri prior to sexual intercourse to prevent the entry of spermatozoa. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C C42771 Intrauterine Device Intra Uterine Device A device usually made of plastic or metal, inserted into the uterus to prevent conception. IUCD can be a coil, loop, triangle, or T in shape; its material can be impregnated with a pharmaceutical agent. The primary action of all IUCDs is the induction of a foreign-body reaction within the endometrium. This sterile inflammatory process is toxic to gametes, primarily spermatozoa, and effectively prevents viable sperm from passing into the fallopian tubes. The copper-bearing device has an independent toxic effect on spermatozoa. The progestin-releasing devices produce changes in endometrial architecture and function that reduce the potential for implantation of a fertilized egg. The progestin effect on the cervical mucus also reduces the penetrability of sperm. Intra Uterine Contraceptive Device is a form of birth control that involves an object placed in the uterus to prevent fertilization of the egg by sperm.IUCD can be a coil, loop, triangle, or T in shape; its material can be impregnated with a pharmaceutical agent. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C C42771 Intrauterine Device Intra Uterine Device A device usually made of plastic or metal, inserted into the uterus to prevent conception. IUCD can be a coil, loop, triangle, or T in shape; its material can be impregnated with a pharmaceutical agent. The primary action of all IUCDs is the induction of a foreign-body reaction within the endometrium. This sterile inflammatory process is toxic to gametes, primarily spermatozoa, and effectively prevents viable sperm from passing into the fallopian tubes. The copper-bearing device has an independent toxic effect on spermatozoa. The progestin-releasing devices produce changes in endometrial architecture and function that reduce the potential for implantation of a fertilized egg. The progestin effect on the cervical mucus also reduces the penetrability of sperm. Intra Uterine Contraceptive Device is a form of birth control that involves an object placed in the uterus to prevent fertilization of the egg by sperm.IUCD can be a coil, loop, triangle, or T in shape; its material can be impregnated with a pharmaceutical agent. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C C4371 Pregnancy Associated Hypertension Pregnancy Induced Hypertension The most common complication of pregnancy. It may appear as chronic hypertension or preeclampsia. It may cause brain hemorrhage, pulmonary edema, abruptio placentae, gestational diabetes mellitus, renal failure, premature delivery and fetal growth abnormalities. C3117 Hypertensive Disorder C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C4371 Pregnancy Associated Hypertension Pregnancy Induced Hypertension The most common complication of pregnancy. It may appear as chronic hypertension or preeclampsia. It may cause brain hemorrhage, pulmonary edema, abruptio placentae, gestational diabetes mellitus, renal failure, premature delivery and fetal growth abnormalities. C3117 Hypertensive Disorder C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C45306 Substance Substance Any matter of defined composition that has discrete existence, whose origin may be biological, mineral or chemical. C89505 C90259 NICHD Pediatric Terminology C C47868 Blood Chemistry Measurement Blood Test The determination of the measured concentrations of chemical constituents of the blood by assay in a clinical laboratory. C49286 Hematology Procedure C90259 NICHD Pediatric Terminology C C47868 Blood Chemistry Measurement Blood Test The determination of the measured concentrations of chemical constituents of the blood by assay in a clinical laboratory. C49286 Hematology Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C4875 Reproductive System Disorder Reproductive System Disorder A non-neoplastic or neoplastic disorder that affects the male or female genital system. Representative examples of non-neoplastic disorders include infection, testicular torsion, endometriosis, and adenomyosis. Representative examples of neoplastic disorders include germ cell tumors, carcinoma, lymphoma, and sarcoma. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C49236 Therapeutic Procedure Therapeutic Procedure An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process. C25218 Intervention or Procedure|Procedure C89506 NICHD Newborn Screening Terminology C C49236 Therapeutic Procedure Therapeutic Procedure An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process. C25218 Intervention or Procedure|Procedure C90259 NICHD Pediatric Terminology C C49236 Therapeutic Procedure Therapeutic Procedure An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process. C25218 Intervention or Procedure|Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C5041 Speech Manifestations Speech Disorder A term referring to disorders characterized by the disruption of normal speech. It includes stuttering, lisps, dysarthria and voice disorders. C26835 Nervous System Disorder|Neurologic Disorder C90259 NICHD Pediatric Terminology C C5041 Speech Manifestations Speech Disorder A term referring to disorders characterized by the disruption of normal speech. It includes stuttering, lisps, dysarthria and voice disorders. C26835 Nervous System Disorder|Neurologic Disorder C97150 NICHD Neurological Development Terminology C C50484 Fetal Cephalhematoma Cephalhematoma A subperiosteal hemorrhage limited to the surface of one cranial bone, a usually benign condition seen in the newborn as a result of bone trauma. C81236 Birth Complication C92719 Fetal Disorder C89506 NICHD Newborn Screening Terminology C C50484 Fetal Cephalhematoma Cephalhematoma A subperiosteal hemorrhage limited to the surface of one cranial bone, a usually benign condition seen in the newborn as a result of bone trauma. C81236 Birth Complication C92719 Fetal Disorder C90259 NICHD Pediatric Terminology C C50484 Fetal Cephalhematoma Cephalhematoma A subperiosteal hemorrhage limited to the surface of one cranial bone, a usually benign condition seen in the newborn as a result of bone trauma. C81236 Birth Complication C92719 Fetal Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C50564 Fetal Hypoxia Fetal Hypoxia Hypoxia in utero, caused by conditions such as inadequate placental function (often abruptio placentae), preeclamptic toxicity, prolapse of the umbilical cord, or complications from anesthetic administration. C3890 Hypoxia C90259 NICHD Pediatric Terminology C C50564 Fetal Hypoxia Fetal Hypoxia Hypoxia in utero, caused by conditions such as inadequate placental function (often abruptio placentae), preeclamptic toxicity, prolapse of the umbilical cord, or complications from anesthetic administration. C3890 Hypoxia C92712 NICHD Pregnancy & Childbirth Terminology C C50791 Urinary Tract Infection Urinary Tract Infection A bacterial infectious process affecting any part of the urinary tract, most commonly the bladder and the urethra. Symptoms include urinary urgency and frequency, burning sensation during urination, lower abdominal discomfort, and cloudy urine. C26726 Infectious Disease C3430 Urinary System Disorder C90259 NICHD Pediatric Terminology C C50791 Urinary Tract Infection Urinary Tract Infection A bacterial infectious process affecting any part of the urinary tract, most commonly the bladder and the urethra. Symptoms include urinary urgency and frequency, burning sensation during urination, lower abdominal discomfort, and cloudy urine. C26726 Infectious Disease C3430 Urinary System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C50896 Intraventricular Brain Hemorrhage Intraventricular Hemorrhage Bleeding into the brain's ventricles. C50438 Intracranial Hemorrhage C90259 NICHD Pediatric Terminology C C50896 Intraventricular Brain Hemorrhage Intraventricular Hemorrhage Bleeding into the brain's ventricles. C50438 Intracranial Hemorrhage C97150 NICHD Neurological Development Terminology C C50917 Premature Labor Premature Labor Ouster of a viable infant before the normal end of gestation, commonly defined as interruption of pregnancy between the twentieth-thirty seventh completed weeks after the onset of the last menstrual cycle. C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C50917 Premature Labor Premature Labor Ouster of a viable infant before the normal end of gestation, commonly defined as interruption of pregnancy between the twentieth-thirty seventh completed weeks after the onset of the last menstrual cycle. C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C52582 Referral Referral Sending a patient from one practitioner to another for health care services. C25218 Intervention or Procedure|Procedure C89506 NICHD Newborn Screening Terminology C C52582 Referral Referral Sending a patient from one practitioner to another for health care services. C25218 Intervention or Procedure|Procedure C90259 NICHD Pediatric Terminology C C61009 Blood Type Blood Type The specific reaction pattern of erythrocytes of an individual to the antisera of one blood group; e.g., the ABO blood group consists of four major blood types: O, A, B, and AB. This classification depends on the presence or absence of two major antigens: A or B. Type O occurs when neither is present and type AB when both are present. The blood type is the genetic phenotype of the individual for one blood group system and may be determined using different antisera available for testing. C92721 Screening or Clinical Tests during Pregnancy C25294 Laboratory Procedure C90259 NICHD Pediatric Terminology C C61009 Blood Type Blood Type The specific reaction pattern of erythrocytes of an individual to the antisera of one blood group; e.g., the ABO blood group consists of four major blood types: O, A, B, and AB. This classification depends on the presence or absence of two major antigens: A or B. Type O occurs when neither is present and type AB when both are present. The blood type is the genetic phenotype of the individual for one blood group system and may be determined using different antisera available for testing. C92721 Screening or Clinical Tests during Pregnancy C25294 Laboratory Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C62103 Device Device An object contrived for a specific purpose. C89505 C90259 NICHD Pediatric Terminology C C62736 Cognitive Assessment Cognitive Assessment The examination of the cognitive capacities or deficits of an individual through the application of tests that probe that individual's ability to perform various mental activities such as perception, learning, and reasoning. C81313 Neurologic Examination|Neurological Examination C89506 NICHD Newborn Screening Terminology C C62736 Cognitive Assessment Cognitive Assessment The examination of the cognitive capacities or deficits of an individual through the application of tests that probe that individual's ability to perform various mental activities such as perception, learning, and reasoning. C81313 Neurologic Examination|Neurological Examination C90259 NICHD Pediatric Terminology C C63711 Neurosensory Disorder Sensory Disorder An interruption or alteration in the sensory activity or functions of the nervous system. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C63711 Neurosensory Disorder Sensory Disorder An interruption or alteration in the sensory activity or functions of the nervous system. C2991 Disease or Disorder|Disease C97150 NICHD Neurological Development Terminology C C64813 Thyrotropin Measurement Thyrotropin Measurement A quantitative measurement of the amount of thyrotropin present in a sample. C74742 Hormone Measurement C89506 NICHD Newborn Screening Terminology C C64813 Thyrotropin Measurement Thyrotropin Measurement A quantitative measurement of the amount of thyrotropin present in a sample. C74742 Hormone Measurement C90259 NICHD Pediatric Terminology C C64848 Hemoglobin Measurement Hemoglobin Measurement A quantitative measurement of the amount of hemoglobin present in a sample. C47868 Blood Test C64430 Protein Measurement C89506 NICHD Newborn Screening Terminology C C64848 Hemoglobin Measurement Hemoglobin Measurement A quantitative measurement of the amount of hemoglobin present in a sample. C47868 Blood Test C64430 Protein Measurement C90259 NICHD Pediatric Terminology C C64848 Hemoglobin Measurement Hemoglobin Measurement A quantitative measurement of the amount of hemoglobin present in a sample. C47868 Blood Test C64430 Protein Measurement C92712 NICHD Pregnancy & Childbirth Terminology C C69055 Contraceptive Sponge Contraceptive Sponge A sponge impregnated with an antispermicidal agent; it is designed to be placed into the vaginal canal to prevent live sperm from entering the uterus. A contraceptive device, made of plastic, contains an antispermicidal agent, designed to be placed into the vaginal canal to prevent live sperm from entering the uterus. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C C69055 Contraceptive Sponge Contraceptive Sponge A sponge impregnated with an antispermicidal agent; it is designed to be placed into the vaginal canal to prevent live sperm from entering the uterus. A contraceptive device, made of plastic, contains an antispermicidal agent, designed to be placed into the vaginal canal to prevent live sperm from entering the uterus. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C C70856 Observation Result Observational Result An outcome of observation represented as a text, qualitative, or quantitative parameter, code, image, graph, etc. C3367 Clinical Finding|Finding C90259 NICHD Pediatric Terminology C C74794 Total Thyroxine Measurement Total Thyroxine Measurement The determination of the amount of free and bound thyroxine present in a sample. C74742 Hormone Measurement C89506 NICHD Newborn Screening Terminology C C74794 Total Thyroxine Measurement Total Thyroxine Measurement The determination of the amount of free and bound thyroxine present in a sample. C74742 Hormone Measurement C90259 NICHD Pediatric Terminology C C75488 Rett Syndrome Rett Syndrome A progressive neurologic disorder caused by mutations in the MECP2 gene on chromosome X. It almost exclusively affects girls. It is characterized by language and learning difficulties, poor communication skills, and repetitive hand motions. Other signs and symptoms include microcephaly, scoliosis, breathing abnormalities, and sleep disturbances. C97179 Pervasive Developmental Disorder C90259 NICHD Pediatric Terminology C C75488 Rett Syndrome Rett Syndrome A progressive neurologic disorder caused by mutations in the MECP2 gene on chromosome X. It almost exclusively affects girls. It is characterized by language and learning difficulties, poor communication skills, and repetitive hand motions. Other signs and symptoms include microcephaly, scoliosis, breathing abnormalities, and sleep disturbances. C97179 Pervasive Developmental Disorder C97150 NICHD Neurological Development Terminology C C78603 Scoliosis Scoliosis A congenital or acquired spine deformity characterized by lateral curvature of the spine. C99064 Spinal Deformity C90259 NICHD Pediatric Terminology C C80083 Fetal Growth Retardation Intrauterine Growth Retardation Fetal Growth Restriction|Fetal Growth Retardation|IUGR|Intrauterine Growth Restriction Inhibition of fetal growth resulting in the inability of the fetus to achieve its potential size. C92719 Fetal Disorder C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C80083 Fetal Growth Retardation Intrauterine Growth Retardation Fetal Growth Restriction|Fetal Growth Retardation|IUGR|Intrauterine Growth Restriction Inhibition of fetal growth resulting in the inability of the fetus to achieve its potential size. C92719 Fetal Disorder C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C81181 Infant Reflex Infant Reflex Primitive reflex actions that newborns display in response to specific stimuli. These reflexes are involuntary and most disappear as the infant matures. C78342 Reflex C89506 NICHD Newborn Screening Terminology C C81181 Infant Reflex Infant Reflex Primitive reflex actions that newborns display in response to specific stimuli. These reflexes are involuntary and most disappear as the infant matures. C78342 Reflex C90259 NICHD Pediatric Terminology C C81184 Vernier Caliper Vernier Caliper A medical device that is a combination of ruler and caliper that can measure the distance between two points. The configuration of this device permits the measurement of internal dimensions. An instrument for measuring external or internal dimensions. It consists of an L-shaped frame with a linear scale along its longer arm and an L-shaped sliding attachment with a vernier, used to read directly the dimension of an object represented by the separation between the inner or outer edges of the two shorter arms. C81182 Measurement Device C89506 NICHD Newborn Screening Terminology C C81184 Vernier Caliper Vernier Caliper A medical device that is a combination of ruler and caliper that can measure the distance between two points. The configuration of this device permits the measurement of internal dimensions. An instrument for measuring external or internal dimensions. It consists of an L-shaped frame with a linear scale along its longer arm and an L-shaped sliding attachment with a vernier, used to read directly the dimension of an object represented by the separation between the inner or outer edges of the two shorter arms. C81182 Measurement Device C90259 NICHD Pediatric Terminology C C81251 Galactose-1-Phosphate Uridyltransferase Measurement Galactose-1-Phosphate Uridyltransferase Measurement The measurement of the galactose-1-phosphate uridyltransferase in a biologic specimen. C64430 Protein Measurement C89506 NICHD Newborn Screening Terminology C C81251 Galactose-1-Phosphate Uridyltransferase Measurement Galactose-1-Phosphate Uridyltransferase Measurement The measurement of the galactose-1-phosphate uridyltransferase in a biologic specimen. C64430 Protein Measurement C90259 NICHD Pediatric Terminology C C81259 Left Ear Left Ear The organ of hearing located on the left side of the head. C12394 Ear C89506 NICHD Newborn Screening Terminology C C81259 Left Ear Left Ear The organ of hearing located on the left side of the head. C12394 Ear C90259 NICHD Pediatric Terminology C C81261 Measuring Tape Measuring Tape A pliable length of fabric, plastic, paper or some composite that is has incremental lengths imprinted on the surface. A pliable length of fabric, plastic, paper or some composite marked off in a linear scale, as of inches or centimeters, for taking measurements. C81182 Measurement Device C89506 NICHD Newborn Screening Terminology C C81261 Measuring Tape Measuring Tape A pliable length of fabric, plastic, paper or some composite that is has incremental lengths imprinted on the surface. A pliable length of fabric, plastic, paper or some composite marked off in a linear scale, as of inches or centimeters, for taking measurements. C81182 Measurement Device C90259 NICHD Pediatric Terminology C C81263 Mental Development Index Mental Development Index A sequential arrangement of information pertaining to the evolution of an individual's cognitive development. C43531 Child Development Status C81314 Newborn Behavioral Examination C89506 NICHD Newborn Screening Terminology C C81263 Mental Development Index Mental Development Index A sequential arrangement of information pertaining to the evolution of an individual's cognitive development. C43531 Child Development Status C81314 Newborn Behavioral Examination C90259 NICHD Pediatric Terminology C C81276 Hemoglobin A to Total Hemoglobin Ratio Measurement Hemoglobin A to Total Hemoglobin Ratio Measurement The determination of the ratio of Hemoglobin A compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage. C64848 Hemoglobin Measurement|Hemoglobin Variant Test C89506 NICHD Newborn Screening Terminology C C81276 Hemoglobin A to Total Hemoglobin Ratio Measurement Hemoglobin A to Total Hemoglobin Ratio Measurement The determination of the ratio of Hemoglobin A compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage. C64848 Hemoglobin Measurement|Hemoglobin Variant Test C90259 NICHD Pediatric Terminology C C81277 Hemoglobin A2 to Total Hemoglobin Ratio Measurement Hemoglobin A2 to Total Hemoglobin Ratio Measurement The determination of the ratio of Hemoglobin A2 compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage. C64848 Hemoglobin Measurement|Hemoglobin Variant Test C89506 NICHD Newborn Screening Terminology C C81277 Hemoglobin A2 to Total Hemoglobin Ratio Measurement Hemoglobin A2 to Total Hemoglobin Ratio Measurement The determination of the ratio of Hemoglobin A2 compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage. C64848 Hemoglobin Measurement|Hemoglobin Variant Test C90259 NICHD Pediatric Terminology C C81278 Hemoglobin C to Total Hemoglobin Ratio Measurement Hemoglobin C to Total Hemoglobin Ratio Measurement The determination of the ratio of Hemoglobin C compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage. C64848 Hemoglobin Measurement|Hemoglobin Variant Test C89506 NICHD Newborn Screening Terminology C C81278 Hemoglobin C to Total Hemoglobin Ratio Measurement Hemoglobin C to Total Hemoglobin Ratio Measurement The determination of the ratio of Hemoglobin C compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage. C64848 Hemoglobin Measurement|Hemoglobin Variant Test C90259 NICHD Pediatric Terminology C C81279 Hemoglobin S to Total Hemoglobin Ratio Measurement Hemoglobin S to Total Hemoglobin Ratio Measurement The determination of the ratio of Hemoglobin S compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage. C64848 Hemoglobin Measurement|Hemoglobin Variant Test C89506 NICHD Newborn Screening Terminology C C81279 Hemoglobin S to Total Hemoglobin Ratio Measurement Hemoglobin S to Total Hemoglobin Ratio Measurement The determination of the ratio of Hemoglobin S compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage. C64848 Hemoglobin Measurement|Hemoglobin Variant Test C90259 NICHD Pediatric Terminology C C81280 Phenylalanine Measurement Phenylalanine Measurement The measurement of the amount of phenylalanine in a biologic specimen. C81183 Measurement of Amino Acid C89506 NICHD Newborn Screening Terminology C C81280 Phenylalanine Measurement Phenylalanine Measurement The measurement of the amount of phenylalanine in a biologic specimen. C81183 Measurement of Amino Acid C90259 NICHD Pediatric Terminology C C81281 Phenylalanine to Tyrosine Ratio Measurement Phenylalanine to Tyrosine Ratio Measurement The determination of the ratio of phenylalanine compared to tyrosine present in a sample. The measurement may be expressed as a ratio or percentage. C81183 Measurement of Amino Acid C89506 NICHD Newborn Screening Terminology C C81281 Phenylalanine to Tyrosine Ratio Measurement Phenylalanine to Tyrosine Ratio Measurement The determination of the ratio of phenylalanine compared to tyrosine present in a sample. The measurement may be expressed as a ratio or percentage. C81183 Measurement of Amino Acid C90259 NICHD Pediatric Terminology C C81285 Right Ear Right Ear The organ of hearing located on the right side of the head. C12394 Ear C89506 NICHD Newborn Screening Terminology C C81285 Right Ear Right Ear The organ of hearing located on the right side of the head. C12394 Ear C90259 NICHD Pediatric Terminology C C81288 S-Beta Thalassemia S-Beta Thalassemia A disorder characterized by the body's inability to synthesize beta-globin chains, leading to the formation of abnormal hemoglobin and anemia. This inherited autosomal recessive blood disorder is caused by germline mutation of the HBB gene. C35069 Thalassemia C89506 NICHD Newborn Screening Terminology C C81288 S-Beta Thalassemia S-Beta Thalassemia A disorder characterized by the body's inability to synthesize beta-globin chains, leading to the formation of abnormal hemoglobin and anemia. This inherited autosomal recessive blood disorder is caused by germline mutation of the HBB gene. C35069 Thalassemia C90259 NICHD Pediatric Terminology C C81308 Galactose Measurement Galactose Measurement The measurement of the amount of galactose in a biologic specimen. C49286 Hematology Procedure C89506 NICHD Newborn Screening Terminology C C81308 Galactose Measurement Galactose Measurement The measurement of the amount of galactose in a biologic specimen. C49286 Hematology Procedure C90259 NICHD Pediatric Terminology C C81310 Lasso-O Measuring Tape Lasso-O Measuring Tape A measuring tape frequently used to measure head circumference in newborns. A measuring tape frequently used to measure head circumference in newborns. It can measure any circumference to the nearest millimeter and is manufactured from paper-thin, non-stretch, non-shrink plastic. C81261 Measuring Tape C89506 NICHD Newborn Screening Terminology C C81310 Lasso-O Measuring Tape Lasso-O Measuring Tape A measuring tape frequently used to measure head circumference in newborns. A measuring tape frequently used to measure head circumference in newborns. It can measure any circumference to the nearest millimeter and is manufactured from paper-thin, non-stretch, non-shrink plastic. C81261 Measuring Tape C90259 NICHD Pediatric Terminology C C81313 Neurologic Examination Neurologic Examination The assessment of the functionality of the brain, spinal column, and nerves. C25214 Evaluation Procedure C89506 NICHD Newborn Screening Terminology C C81313 Neurologic Examination Neurologic Examination The assessment of the functionality of the brain, spinal column, and nerves. C25214 Evaluation Procedure C90259 NICHD Pediatric Terminology C C81315 Phenylketonuria Phenylketonuria A disorder characterized by the body's inability to break down and utilize the essential amino acid phenylalanine. C97090 Amino Acid Metabolism Disorder C85866 Autosomal Recessive Hereditary Disorder C89506 NICHD Newborn Screening Terminology C C81315 Phenylketonuria Phenylketonuria A disorder characterized by the body's inability to break down and utilize the essential amino acid phenylalanine. C97090 Amino Acid Metabolism Disorder C85866 Autosomal Recessive Hereditary Disorder C90259 NICHD Pediatric Terminology C C81325 Transferase Deficiency Galactosemia Transferase Deficient Galactosemia A disorder characterized by the body's inability to metabolize galactose. This type of galactosemia is caused by germline mutations in the GALT gene which leads to the inhibition in the activity of the enzyme galactose-1-phosphate uridyl transferase. C34816 Congenital Metabolic Disorder|Inborn Error of Metabolism C89506 NICHD Newborn Screening Terminology C C81325 Transferase Deficiency Galactosemia Transferase Deficient Galactosemia A disorder characterized by the body's inability to metabolize galactose. This type of galactosemia is caused by germline mutations in the GALT gene which leads to the inhibition in the activity of the enzyme galactose-1-phosphate uridyl transferase. C34816 Congenital Metabolic Disorder|Inborn Error of Metabolism C90259 NICHD Pediatric Terminology C C81326 Elevated Test Result Elevated Test Result A result of a test that is higher than a previous value or a normal range of values. C77140 Clinical Test Result|Evaluation Finding C89506 NICHD Newborn Screening Terminology C C81326 Elevated Test Result Elevated Test Result A result of a test that is higher than a previous value or a normal range of values. C77140 Clinical Test Result|Evaluation Finding C90259 NICHD Pediatric Terminology C C84480 Heart Murmur Heart Murmur A periodic humming or blowing sound heard on auscultation of the heart that can indicate the presence of cardiac disease; murmurs are the result of vibrations caused by the turbulent flow of blood in the heart or great vessels. Murmurs are characterized according to the area of generation (mitral, aortic, tricuspid, or pulmonary) and according to the period of the cycle (systolic or diastolic). C35552 Cardiovascular Finding C89506 NICHD Newborn Screening Terminology C C84480 Heart Murmur Heart Murmur A periodic humming or blowing sound heard on auscultation of the heart that can indicate the presence of cardiac disease; murmurs are the result of vibrations caused by the turbulent flow of blood in the heart or great vessels. Murmurs are characterized according to the area of generation (mitral, aortic, tricuspid, or pulmonary) and according to the period of the cycle (systolic or diastolic). C35552 Cardiovascular Finding C90259 NICHD Pediatric Terminology C C84504 Rh Incompatibility Rh Incompatibility A complication during pregnancy; it occurs when the mother is Rh-negative and the infant is Rh-positive. The mother's body develops antibodies against the fetal red blood cells leading to their destruction. This complication generally does not affect first-born Rh-positive babies. Rh-positive newborn babies from subsequent pregnancies develop complications of Rh incompatibility which include hemolysis, jaundice, enlarged liver and spleen, petechiae, hypotonia, neurologic damage, and heart problems. C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C84504 Rh Incompatibility Rh Incompatibility A complication during pregnancy; it occurs when the mother is Rh-negative and the infant is Rh-positive. The mother's body develops antibodies against the fetal red blood cells leading to their destruction. This complication generally does not affect first-born Rh-positive babies. Rh-positive newborn babies from subsequent pregnancies develop complications of Rh incompatibility which include hemolysis, jaundice, enlarged liver and spleen, petechiae, hypotonia, neurologic damage, and heart problems. C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C84641 Clubfoot Clubfoot The most common congenital deformation of the foot, occurring in 1 of 1,000 live births. The most common form is talipes equinovarus, where the deformed foot is turned downward and inward sharply. C84978 Congenital Skeletal Dysplasia C89506 NICHD Newborn Screening Terminology C C84641 Clubfoot Clubfoot The most common congenital deformation of the foot, occurring in 1 of 1,000 live births. The most common form is talipes equinovarus, where the deformed foot is turned downward and inward sharply. C84978 Congenital Skeletal Dysplasia C90259 NICHD Pediatric Terminology C C84669 Dextrocardia Dextrocardia A rare congenital abnormality in which the heart is located in the right side of the chest. It is associated with other congenital heart defects. C95834 Congenital Heart Disease C89506 NICHD Newborn Screening Terminology C C84669 Dextrocardia Dextrocardia A rare congenital abnormality in which the heart is located in the right side of the chest. It is associated with other congenital heart defects. C95834 Congenital Heart Disease C90259 NICHD Pediatric Terminology C C84915 Necrotizing Enterocolitis Necrotizing Enterocolitis A serious, life-threatening disorder characterized by necrotic changes affecting portions of the small and large intestine. It is usually seen in neonates, particularly premature infants. Signs and symptoms include abdominal distention and tenderness, intestinal bleeding and ileus. It may lead to cardiovascular collapse and shock. C97171 Congenital Abnormality of the Digestive System C93210 Inflammatory Disorder C90259 NICHD Pediatric Terminology C C84915 Necrotizing Enterocolitis Necrotizing Enterocolitis A serious, life-threatening disorder characterized by necrotic changes affecting portions of the small and large intestine. It is usually seen in neonates, particularly premature infants. Signs and symptoms include abdominal distention and tenderness, intestinal bleeding and ileus. It may lead to cardiovascular collapse and shock. C97171 Congenital Abnormality of the Digestive System C93210 Inflammatory Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C85021 Preeclampsia Preeclampsia A pregnancy-related disorder characterized by an increase in the blood pressure after the twentieth week of gestation, and by the presence of proteinuria. It may appear up to six weeks post-partum. It may lead to eclampsia with development of tonic-clonic seizures. C4371 Pregnancy Induced Hypertension|Pregnancy-Induced Hypertension C89506 NICHD Newborn Screening Terminology C C85021 Preeclampsia Preeclampsia A pregnancy-related disorder characterized by an increase in the blood pressure after the twentieth week of gestation, and by the presence of proteinuria. It may appear up to six weeks post-partum. It may lead to eclampsia with development of tonic-clonic seizures. C4371 Pregnancy Induced Hypertension|Pregnancy-Induced Hypertension C90259 NICHD Pediatric Terminology C C85021 Preeclampsia Preeclampsia A pregnancy-related disorder characterized by an increase in the blood pressure after the twentieth week of gestation, and by the presence of proteinuria. It may appear up to six weeks post-partum. It may lead to eclampsia with development of tonic-clonic seizures. C4371 Pregnancy Induced Hypertension|Pregnancy-Induced Hypertension C92712 NICHD Pregnancy & Childbirth Terminology C C87065 Cyanotic Body Cyanotic Body Blue- or purplish-colored body; this is caused by excessive amounts of deoxygenated hemoglobin in the skin vessels of the body. C26737 Cyanosis C89506 NICHD Newborn Screening Terminology C C87065 Cyanotic Body Cyanotic Body Blue- or purplish-colored body; this is caused by excessive amounts of deoxygenated hemoglobin in the skin vessels of the body. C26737 Cyanosis C90259 NICHD Pediatric Terminology C C87066 Cyanotic Limbs Cyanotic Limbs Blue- or purplish-colored limbs; this is caused by excessive amounts of deoxygenated hemoglobin in the skin vessels of the limbs. C26737 Cyanosis C89506 NICHD Newborn Screening Terminology C C87066 Cyanotic Limbs Cyanotic Limbs Blue- or purplish-colored limbs; this is caused by excessive amounts of deoxygenated hemoglobin in the skin vessels of the limbs. C26737 Cyanosis C90259 NICHD Pediatric Terminology C C87071 Ear Dimple Ear Dimple A pit or dimple in front of the ear of a newborn is a common finding; rarely, such a dimple may get infected, which will be manifested with redness and swelling and will require medical attention. C100104 Signs or Symptoms C89506 NICHD Newborn Screening Terminology C C87071 Ear Dimple Ear Dimple A pit or dimple in front of the ear of a newborn is a common finding; rarely, such a dimple may get infected, which will be manifested with redness and swelling and will require medical attention. C100104 Signs or Symptoms C90259 NICHD Pediatric Terminology C C87076 Frenulum Frenulum A small fold of tissue that limits the movements of an organ or body part; for example, the lingual frenulum connects the tongue to the floor of the mouth and restrains its movement. C32221 Body Part|Body Structure C89506 NICHD Newborn Screening Terminology C C87076 Frenulum Frenulum A small fold of tissue that limits the movements of an organ or body part; for example, the lingual frenulum connects the tongue to the floor of the mouth and restrains its movement. C32221 Body Part|Body Structure C90259 NICHD Pediatric Terminology C C87083 Heterotaxia Heterotaxia The abnormal arrangement or position of thoracic and/or abdominal organs in relation to each other, often occurring in a right/left transposition. C97151 Congenital Systemic Disorder C89506 NICHD Newborn Screening Terminology C C87083 Heterotaxia Heterotaxia The abnormal arrangement or position of thoracic and/or abdominal organs in relation to each other, often occurring in a right/left transposition. C97151 Congenital Systemic Disorder C90259 NICHD Pediatric Terminology C C87084 Hyperemesis Gravidarum Hyperemesis Gravidarum Severe, intractable vomiting during pregnancy (usually the first trimester) accompanied by dehydration, weight loss, and electrolyte imbalances. C34941 Complication Related to Pregnancy|Pregnancy Complication C89506 NICHD Newborn Screening Terminology C C87084 Hyperemesis Gravidarum Hyperemesis Gravidarum Severe, intractable vomiting during pregnancy (usually the first trimester) accompanied by dehydration, weight loss, and electrolyte imbalances. C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C87084 Hyperemesis Gravidarum Hyperemesis Gravidarum Severe, intractable vomiting during pregnancy (usually the first trimester) accompanied by dehydration, weight loss, and electrolyte imbalances. C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C87090 Labial Fusion Labial Fusion Usually found in girls between 6 months and 6 years of age, this condition occurs wherein the labia grow together instead of as 2 separate folds, thereby blocking the opening of the vagina. It is caused by conditions such as repeated diaper rash, urine and stool infections, and sexual abuse. The condition often spontaneously corrects or responds to the application of estrogen cream. C103185 Congenital Abnormality of the Reproductive System C89506 NICHD Newborn Screening Terminology C C87090 Labial Fusion Labial Fusion Usually found in girls between 6 months and 6 years of age, this condition occurs wherein the labia grow together instead of as 2 separate folds, thereby blocking the opening of the vagina. It is caused by conditions such as repeated diaper rash, urine and stool infections, and sexual abuse. The condition often spontaneously corrects or responds to the application of estrogen cream. C103185 Congenital Abnormality of the Reproductive System C90259 NICHD Pediatric Terminology C C87101 Neonatal Abstinence Syndrome Neonatal Abstinence Syndrome A constellation of signs and symptoms observable in a neonate that are consistent with maternal narcotic abuse or withdrawal while pregnant. C101321 Drug Withdrawal Syndrome in Newborn C89506 NICHD Newborn Screening Terminology C C87101 Neonatal Abstinence Syndrome Neonatal Abstinence Syndrome A constellation of signs and symptoms observable in a neonate that are consistent with maternal narcotic abuse or withdrawal while pregnant. C101321 Drug Withdrawal Syndrome in Newborn C90259 NICHD Pediatric Terminology C C87107 Pupils Equal Round and Reactive to Light Result Pupils Equal Round and Reactive to Light Result While performing an assessment of the eyes, the examiner notes whether the pupils are equal, round, and reactive to light. If all findings are normal, the abbreviation PERRL is noted in the examiner's account of the physical examination. C77140 Clinical Test Result|Evaluation Finding C89506 NICHD Newborn Screening Terminology C C87107 Pupils Equal Round and Reactive to Light Result Pupils Equal Round and Reactive to Light Result While performing an assessment of the eyes, the examiner notes whether the pupils are equal, round, and reactive to light. If all findings are normal, the abbreviation PERRL is noted in the examiner's account of the physical examination. C77140 Clinical Test Result|Evaluation Finding C90259 NICHD Pediatric Terminology C C87108 Pupils Equal Round and Reactive to Light and Accommodation Result Pupils Equal Round and Reactive to Light and Accommodation Result While performing an assessment of the eyes, the examiner notes whether the pupils are equal and round, reactive to light, and have the ability to accommodate. If all findings are normal, the abbreviation PERRLA is noted in the examiner's account of the physical examination. C77140 Clinical Test Result|Evaluation Finding C89506 NICHD Newborn Screening Terminology C C87108 Pupils Equal Round and Reactive to Light and Accommodation Result Pupils Equal Round and Reactive to Light and Accommodation Result While performing an assessment of the eyes, the examiner notes whether the pupils are equal and round, reactive to light, and have the ability to accommodate. If all findings are normal, the abbreviation PERRLA is noted in the examiner's account of the physical examination. C77140 Clinical Test Result|Evaluation Finding C90259 NICHD Pediatric Terminology C C87113 Premature Rupture of Membrane Premature Rupture of Membranes PROM The condition when a patient who is beyond 37 weeks gestation presents with rupture of membranes prior to the onset of labor. Rupture of membranes is diagnosed by speculum vaginal examination of the cervix and vaginal cavity, which will show pooling of fluid in the vagina or leakage of fluid from the cervix. Preterm PROM (known as PPROM) refers to a patient who has not yet reached 37 weeks gestation and presents with rupture of membranes. C34941 Complication Related to Pregnancy|Pregnancy Complication C89506 NICHD Newborn Screening Terminology C C87113 Premature Rupture of Membrane Premature Rupture of Membranes PROM The condition when a patient who is beyond 37 weeks gestation presents with rupture of membranes prior to the onset of labor. Rupture of membranes is diagnosed by speculum vaginal examination of the cervix and vaginal cavity, which will show pooling of fluid in the vagina or leakage of fluid from the cervix. Preterm PROM (known as PPROM) refers to a patient who has not yet reached 37 weeks gestation and presents with rupture of membranes. C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C87113 Premature Rupture of Membrane Premature Rupture of Membranes PROM The condition when a patient who is beyond 37 weeks gestation presents with rupture of membranes prior to the onset of labor. Rupture of membranes is diagnosed by speculum vaginal examination of the cervix and vaginal cavity, which will show pooling of fluid in the vagina or leakage of fluid from the cervix. Preterm PROM (known as PPROM) refers to a patient who has not yet reached 37 weeks gestation and presents with rupture of membranes. C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C87114 Proptosis Proptosis Abnormal protrusion of one or both eyes from the socket; causes include hyperthyroidism (particularly Graves disease); bleeding behind the eye; infection, inflammation, or tumors of the orbit; and vascular disorders. C35126 Vision Disorder|Visual System Disorder C89506 NICHD Newborn Screening Terminology C C87114 Proptosis Proptosis Abnormal protrusion of one or both eyes from the socket; causes include hyperthyroidism (particularly Graves disease); bleeding behind the eye; infection, inflammation, or tumors of the orbit; and vascular disorders. C35126 Vision Disorder|Visual System Disorder C90259 NICHD Pediatric Terminology C C87115 Hemolytic Disease of the Newborn Hemolytic Disease of the Newborn A disorder caused when there is a Rh-factor blood-type incompatibility between the mother and fetus, and the mother's immune system forms antibodies that attack the red blood cells of her unborn child. This disorder can only occur if the mother is Rh-negative and the fetus is Rh-positive. C3092 Hemoglobinopathy C98996 Neonatal Disorder C89506 NICHD Newborn Screening Terminology C C87115 Hemolytic Disease of the Newborn Hemolytic Disease of the Newborn A disorder caused when there is a Rh-factor blood-type incompatibility between the mother and fetus, and the mother's immune system forms antibodies that attack the red blood cells of her unborn child. This disorder can only occur if the mother is Rh-negative and the fetus is Rh-positive. C3092 Hemoglobinopathy C98996 Neonatal Disorder C90259 NICHD Pediatric Terminology C C87118 Sacral Dimple Sacral Dimple A sacral dimple, or pilonidal dimple, is a small hollow area or sinus present at birth and located just above the crease of the buttocks. In most cases, pilonidal dimples are benign and may just be accompanied by increased hair growth in the area. C100104 Signs or Symptoms C89506 NICHD Newborn Screening Terminology C C87118 Sacral Dimple Sacral Dimple A sacral dimple, or pilonidal dimple, is a small hollow area or sinus present at birth and located just above the crease of the buttocks. In most cases, pilonidal dimples are benign and may just be accompanied by increased hair growth in the area. C100104 Signs or Symptoms C90259 NICHD Pediatric Terminology C C87120 Single Palmar Crease Single Palmar Crease A single transverse palmar crease is found in 5% of newborns and is frequently inherited as a familial trait. However, single palmar creases can be associated with Down's syndrome and other genetic disorders, or with fetal alcohol syndrome. C100104 Signs or Symptoms C89506 NICHD Newborn Screening Terminology C C87120 Single Palmar Crease Single Palmar Crease A single transverse palmar crease is found in 5% of newborns and is frequently inherited as a familial trait. However, single palmar creases can be associated with Down's syndrome and other genetic disorders, or with fetal alcohol syndrome. C100104 Signs or Symptoms C90259 NICHD Pediatric Terminology C C87121 Situs Inversus Situs Inversus A congenital condition in which there is complete right-to-left reversal of the position of the major thoracic and abdominal organs (that is, they are arranged in a mirror image of the normal positioning). C97151 Congenital Systemic Disorder C89506 NICHD Newborn Screening Terminology C C87121 Situs Inversus Situs Inversus A congenital condition in which there is complete right-to-left reversal of the position of the major thoracic and abdominal organs (that is, they are arranged in a mirror image of the normal positioning). C97151 Congenital Systemic Disorder C90259 NICHD Pediatric Terminology C C87167 Eclampsia Eclampsia A potentially life-threatening disorder in pregnant or puerperal women manifested by convulsions in association with hypertension, edema, and/or proteinuria. C35169 Pregnancy Disorder C89506 NICHD Newborn Screening Terminology C C87167 Eclampsia Eclampsia A potentially life-threatening disorder in pregnant or puerperal women manifested by convulsions in association with hypertension, edema, and/or proteinuria. C35169 Pregnancy Disorder C90259 NICHD Pediatric Terminology C C87167 Eclampsia Eclampsia A potentially life-threatening disorder in pregnant or puerperal women manifested by convulsions in association with hypertension, edema, and/or proteinuria. C35169 Pregnancy Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C87169 High Pitched Cry High Pitched Cry A symptom in infants that could possibly indicate the presence of one of an array of medical conditions or congenital syndromes, including birth trauma, craniosynostosis, Arnold-Chiari deformity, meningitis, and cri-du-chat syndrome (deletion of the short arm of chromosome 5). C61043 Voice Finding C100104 Signs or Symptoms C89506 NICHD Newborn Screening Terminology C C87169 High Pitched Cry High Pitched Cry A symptom in infants that could possibly indicate the presence of one of an array of medical conditions or congenital syndromes, including birth trauma, craniosynostosis, Arnold-Chiari deformity, meningitis, and cri-du-chat syndrome (deletion of the short arm of chromosome 5). C61043 Voice Finding C100104 Signs or Symptoms C90259 NICHD Pediatric Terminology C C89328 Pediatric Disorder Pediatric Disease or Disorder A non-neoplastic or neoplastic disorder which occurs during childhood. C2991 Disease or Disorder|Disease C89506 NICHD Newborn Screening Terminology C C89328 Pediatric Disorder Pediatric Disease or Disorder A non-neoplastic or neoplastic disorder which occurs during childhood. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C89329 Conduct Disorder Conduct Disorder A disorder diagnosed in childhood or adolescence age group characterized by aggressive behavior, deceitfulness, destruction of property or violation of rules that is persistent and repetitive, and within a one year period. C35470 Behavior Finding|Behavioral Disorder C90259 NICHD Pediatric Terminology C C89331 Early Adolescence Early Adolescence A transitional time in an individual's life between childhood and adolescence. This phase marks the start of physical, physiological and psychological changes that characterize pubertal growth and development. A human life stage that begins at twelve years of age and continues until eighteen complete years of age. This phase marks the start of physical, physiological and psychological changes that characterize pubertal growth and development. C39298 Adolescence C90259 NICHD Pediatric Terminology C C89337 Congenital Musculoskeletal Defect Congenital Abnormality of the Musculoskeletal System An abnormality of the musculoskeletal system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C27574 Musculoskeletal System Disorder C89506 NICHD Newborn Screening Terminology C C89337 Congenital Musculoskeletal Defect Congenital Abnormality of the Musculoskeletal System An abnormality of the musculoskeletal system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C27574 Musculoskeletal System Disorder C90259 NICHD Pediatric Terminology C C89339 Neurological Screening Neurological Screening A specific type of neurologic examination for early detection of disease(s) and/or disorder(s). C81313 Neurologic Examination|Neurological Examination C89506 NICHD Newborn Screening Terminology C C89339 Neurological Screening Neurological Screening A specific type of neurologic examination for early detection of disease(s) and/or disorder(s). C81313 Neurologic Examination|Neurological Examination C90259 NICHD Pediatric Terminology C C89340 Obstetric Procedure Obstetric Procedure Any pregnancy or childbirth related procedure associated with a mother during her reproductive years. C25218 Intervention or Procedure|Procedure C90259 NICHD Pediatric Terminology C C89344 Late Adolescence Late Adolescence A transitional time in an individual's life between adolescence and early adulthood. This phase includes the final stages of pubertal growth and development as well as the attainment of significant psycho-social milestones. A human life stage that begins at nineteen years of age and continues until twenty-one complete years of age. This phase includes the final stages of pubertal growth and development as well as the attainment of significant psycho-social milestones. C39298 Adolescence C90259 NICHD Pediatric Terminology C C90341 Pediatric Intervention or Procedure Pediatric Intervention or Procedure A diagnostic or therapeutic course of action usually performed on patients under the age of 18. C25218 Intervention or Procedure|Procedure C90259 NICHD Pediatric Terminology C C9039 Cervical Carcinoma Cervical Carcinoma A carcinoma arising from either the exocervical squamous epithelium or the endocervical glandular epithelium. The major histologic types of cervical carcinoma are: squamous carcinoma, adenocarcinoma, adenosquamous carcinoma, adenoid cystic carcinoma and undifferentiated carcinoma. C3262 Neoplasm|Neoplastic Disease C90259 NICHD Pediatric Terminology C C9039 Cervical Carcinoma Cervical Carcinoma A carcinoma arising from either the exocervical squamous epithelium or the endocervical glandular epithelium. The major histologic types of cervical carcinoma are: squamous carcinoma, adenocarcinoma, adenosquamous carcinoma, adenoid cystic carcinoma and undifferentiated carcinoma. C3262 Neoplasm|Neoplastic Disease C96388 NICHD Childhood Immunization Terminology C C90498 Risk Factor Assessment Risk Factor Assessment A systematic gathering of information regarding the variables associated with an individual's increased risk of disease or infection. C92721 Screening or Clinical Tests during Pregnancy C89506 NICHD Newborn Screening Terminology C C90498 Risk Factor Assessment Risk Factor Assessment A systematic gathering of information regarding the variables associated with an individual's increased risk of disease or infection. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C C91199 Vaginal Ring Dosage Form Vaginal Ring A ring composed of active and/or inert ingredient(s), intended for administration in or around the vagina. A contraceptive device in the shape of a ring composed of active and/or inert ingredient(s), intended for administration in or around the vagina, to prevent conception. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C C91199 Vaginal Ring Dosage Form Vaginal Ring A ring composed of active and/or inert ingredient(s), intended for administration in or around the vagina. A contraceptive device in the shape of a ring composed of active and/or inert ingredient(s), intended for administration in or around the vagina, to prevent conception. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C C9229 Systemic Disease Systemic Disorder A clinical course finding indicating that a disease presents with systemic manifestations. A disorder that affects in multiple tissue types or in multiple organ systemsis, or affects the body as a whole. C2991 Disease or Disorder|Disease C90259 NICHD Pediatric Terminology C C92561 Developmental Coordination Disorder Developmental Coordination Disorder Developmental Dyspraxia A disorder characterized by an impairment in the development of an individual's motor coordination skills; this impairment in motor development is not due to a medical condition. C89338 Neurodevelopmental Disorder C92190 Childhood Mental Disorder C90259 NICHD Pediatric Terminology C C92561 Developmental Coordination Disorder Developmental Coordination Disorder Developmental Dyspraxia A disorder characterized by an impairment in the development of an individual's motor coordination skills; this impairment in motor development is not due to a medical condition. C89338 Neurodevelopmental Disorder C92190 Childhood Mental Disorder C97150 NICHD Neurological Development Terminology C C92621 Acute Stress Disorder Acute Stress Disorder An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by dissociative symptoms; vivid recollections of the traumatic event; avoidance of stimuli associated with the traumatic event; and a constant state of hyperarousal for no more than one month. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology C C92621 Acute Stress Disorder Acute Stress Disorder An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by dissociative symptoms; vivid recollections of the traumatic event; avoidance of stimuli associated with the traumatic event; and a constant state of hyperarousal for no more than one month. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology C C92622 Generalized Anxiety Disorder Generalized Anxiety Disorder An anxiety disorder characterized by excessive and difficult-to-control worry about a number of life situations. The worry is accompanied by restlessness, fatigue, inability to concentrate, irritability, muscle tension, and/or sleep disturbance and lasts for at least 6 months. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology C C92622 Generalized Anxiety Disorder Generalized Anxiety Disorder An anxiety disorder characterized by excessive and difficult-to-control worry about a number of life situations. The worry is accompanied by restlessness, fatigue, inability to concentrate, irritability, muscle tension, and/or sleep disturbance and lasts for at least 6 months. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology C C92715 Fetal Heart Finding Fetal Heart Finding An observation of the fetal heart that may or may not be abnormal. C92711 Fetal Finding C90259 NICHD Pediatric Terminology C C92715 Fetal Heart Finding Fetal Heart Finding An observation of the fetal heart that may or may not be abnormal. C92711 Fetal Finding C92712 NICHD Pregnancy & Childbirth Terminology C C92718 Finding During Childbirth Labor Finding during Childbirth Labor Symptom, signs, test results in a pregnant mother childbirth. C70856 Observational Result C90259 NICHD Pediatric Terminology C C92718 Finding During Childbirth Labor Finding during Childbirth Labor Symptom, signs, test results in a pregnant mother childbirth. C70856 Observational Result C92712 NICHD Pregnancy & Childbirth Terminology C C92726 Abnormal Pregnancy Abnormal Pregnancy A pregnancy that is complicated and affected by an abnormal finding or disease condition in either the fetus and/or the mother. C35169 Pregnancy Disorder C90259 NICHD Pediatric Terminology C C92726 Abnormal Pregnancy Abnormal Pregnancy A pregnancy that is complicated and affected by an abnormal finding or disease condition in either the fetus and/or the mother. C35169 Pregnancy Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C92744 Blood Glucose Measurement Blood Glucose Measurement A quantitative measurement for assessing the amount of glucose present in a blood sample. C47868 Blood Test C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C C92744 Blood Glucose Measurement Blood Glucose Measurement A quantitative measurement for assessing the amount of glucose present in a blood sample. C47868 Blood Test C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92758 Contraceptive Coil Contraceptive Coil Loop A medical device that is inserted into the uterus to prevent pregnancy. A contraceptive device, which is shaped like a coil, and is inserted into the uterus to prevent pregnancy. C42771 Intra Uterine Device C90259 NICHD Pediatric Terminology C C92758 Contraceptive Coil Contraceptive Coil Loop A medical device that is inserted into the uterus to prevent pregnancy. A contraceptive device, which is shaped like a coil, and is inserted into the uterus to prevent pregnancy. C42771 Intra Uterine Device C92712 NICHD Pregnancy & Childbirth Terminology C C92760 Contraceptive Patch Contraceptive Patch A dermal patch that contains estrogen and progestin hormones for release and absorption through the skin and into the body to prevent pregnancy. A a medicated adhesive patch that is placed on the skin to deliver estrogen and progestin hormones for release and absorption through the skin and into the body to prevent pregnancy. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C C92760 Contraceptive Patch Contraceptive Patch A dermal patch that contains estrogen and progestin hormones for release and absorption through the skin and into the body to prevent pregnancy. A a medicated adhesive patch that is placed on the skin to deliver estrogen and progestin hormones for release and absorption through the skin and into the body to prevent pregnancy. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C C92770 Early Fetal Heart Rate Deceleration Early Deceleration A decrease in the fetal heart rate that occurs in the initial stages of uterine contractions. C92789 Fetal Heart Deceleration|Fetal Heart Rate Deceleration C90259 NICHD Pediatric Terminology C C92770 Early Fetal Heart Rate Deceleration Early Deceleration A decrease in the fetal heart rate that occurs in the initial stages of uterine contractions. C92789 Fetal Heart Deceleration|Fetal Heart Rate Deceleration C92712 NICHD Pregnancy & Childbirth Terminology C C92780 Fetal Alcohol Spectrum Disorder Fetal Alcohol Spectrum Disorder A group of disorders caused by a prenatal exposure to maternal consumption of alcohol leading to a range of behavioral, cognitive and neurological deficits in the offspring. It is characterized by physical growth problems, distinct facies, and varying psycho-neurological issues. C98977 Fetus or Newborn Affected by Maternal Transmission of Substance C92719 Fetal Disorder C90259 NICHD Pediatric Terminology C C92780 Fetal Alcohol Spectrum Disorder Fetal Alcohol Spectrum Disorder A group of disorders caused by a prenatal exposure to maternal consumption of alcohol leading to a range of behavioral, cognitive and neurological deficits in the offspring. It is characterized by physical growth problems, distinct facies, and varying psycho-neurological issues. C98977 Fetus or Newborn Affected by Maternal Transmission of Substance C92719 Fetal Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C92782 Fetal Bradycardia Fetal Bradycardia A decrease in the fetal heart rate below normal baseline values. C92715 Fetal Heart Finding C90259 NICHD Pediatric Terminology C C92782 Fetal Bradycardia Fetal Bradycardia A decrease in the fetal heart rate below normal baseline values. C92715 Fetal Heart Finding C92712 NICHD Pregnancy & Childbirth Terminology C C92793 Fetal Malpresentation Malpresentation of Fetus An abnormal position assumed by the fetus in the birth canal during the childbirth process. C81236 Birth Complication C92724 Fetal Presentation C90259 NICHD Pediatric Terminology C C92793 Fetal Malpresentation Malpresentation of Fetus An abnormal position assumed by the fetus in the birth canal during the childbirth process. C81236 Birth Complication C92724 Fetal Presentation C92712 NICHD Pregnancy & Childbirth Terminology C C92796 Fetal Tachycardia Fetal Tachycardia An increase in the fetal heart rate above the normal baseline values. C92715 Fetal Heart Finding C92719 Fetal Disorder C90259 NICHD Pediatric Terminology C C92796 Fetal Tachycardia Fetal Tachycardia An increase in the fetal heart rate above the normal baseline values. C92715 Fetal Heart Finding C92719 Fetal Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C92816 Intermittent Fetal Heart Rate Deceleration Intermittent Deceleration An infrequently repeated decrease in the fetal heart rate that occurs in conjunction with a uterine contraction. C92789 Fetal Heart Deceleration|Fetal Heart Rate Deceleration C90259 NICHD Pediatric Terminology C C92816 Intermittent Fetal Heart Rate Deceleration Intermittent Deceleration An infrequently repeated decrease in the fetal heart rate that occurs in conjunction with a uterine contraction. C92789 Fetal Heart Deceleration|Fetal Heart Rate Deceleration C92712 NICHD Pregnancy & Childbirth Terminology C C92822 Late Fetal Heart Rate Deceleration Late Deceleration A decrease in the fetal heart rate that occurs gradually after the peak in uterine contraction. C92789 Fetal Heart Deceleration|Fetal Heart Rate Deceleration C90259 NICHD Pediatric Terminology C C92822 Late Fetal Heart Rate Deceleration Late Deceleration A decrease in the fetal heart rate that occurs gradually after the peak in uterine contraction. C92789 Fetal Heart Deceleration|Fetal Heart Rate Deceleration C92712 NICHD Pregnancy & Childbirth Terminology C C92823 Late Pregnancy Bleeding Late Pregnancy Bleeding An abnormal bleeding through the vagina that occurs during the last trimester of pregnancy. C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C92823 Late Pregnancy Bleeding Late Pregnancy Bleeding An abnormal bleeding through the vagina that occurs during the last trimester of pregnancy. C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C92824 Leakage of Amniotic Fluid Leakage of Amniotic Fluid The discharge of amniotic fluid vaginally due to a tear or rupture in the amniotic membrane. C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C92824 Leakage of Amniotic Fluid Leakage of Amniotic Fluid The discharge of amniotic fluid vaginally due to a tear or rupture in the amniotic membrane. C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C92828 Maternal Fever Maternal Fever The elevation of body temperature in a pregnant mother above 38 degrees C or more than 101 degrees F, and may be indicative of an infection. C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C92828 Maternal Fever Maternal Fever The elevation of body temperature in a pregnant mother above 38 degrees C or more than 101 degrees F, and may be indicative of an infection. C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C92829 Maternal Hypotension Maternal Hypotension A decrease in the systolic blood pressure in a pregnant mother for values that are less than 25% of her normal blood pressure levels or arbitrarily, one that is less than 100 mm Hg during pregnancy. C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C92829 Maternal Hypotension Maternal Hypotension A decrease in the systolic blood pressure in a pregnant mother for values that are less than 25% of her normal blood pressure levels or arbitrarily, one that is less than 100 mm Hg during pregnancy. C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C92839 Oligohydramnios Oligohydramnios A lower than normal volume of amniotic fluid observed by ultrasound during pregnancy. C92719 Fetal Disorder C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C92839 Oligohydramnios Oligohydramnios A lower than normal volume of amniotic fluid observed by ultrasound during pregnancy. C92719 Fetal Disorder C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C92841 Perinatal Death Perinatal Death The death of an infant before birth after 28 weeks of gestation or shortly after birth. C35095 Perinatal Disorder C90491 Pregnancy Outcome C90259 NICHD Pediatric Terminology C C92841 Perinatal Death Perinatal Death The death of an infant before birth after 28 weeks of gestation or shortly after birth. C35095 Perinatal Disorder C90491 Pregnancy Outcome C92712 NICHD Pregnancy & Childbirth Terminology C C92848 Polyhydramnios Polyhydramnios An excess quantity of amniotic fluid in the amniotic sac as compared to normal values. C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C92848 Polyhydramnios Polyhydramnios An excess quantity of amniotic fluid in the amniotic sac as compared to normal values. C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C92853 Postpartum Hemorrhage Postpartum Hemorrhage Hemorrhage defined as a blood loss in excess of 500 mL after vaginal delivery or more than 1000 mL after a cesarean delivery. C26791 Hemorrhage C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C92853 Postpartum Hemorrhage Postpartum Hemorrhage Hemorrhage defined as a blood loss in excess of 500 mL after vaginal delivery or more than 1000 mL after a cesarean delivery. C26791 Hemorrhage C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C92863 Prolonged Fetal Heart Rate Acceleration Prolonged Acceleration An abrupt and extended increase in the fetal heart rate during labor contractions. C92788 Fetal Heart Acceleration|Fetal Heart Rate Acceleration C90259 NICHD Pediatric Terminology C C92863 Prolonged Fetal Heart Rate Acceleration Prolonged Acceleration An abrupt and extended increase in the fetal heart rate during labor contractions. C92788 Fetal Heart Acceleration|Fetal Heart Rate Acceleration C92712 NICHD Pregnancy & Childbirth Terminology C C92864 Prolonged Fetal Heart Rate Deceleration Prolonged Deceleration An extended decrease in the fetal heart rate compared to the normal baseline values. C92789 Fetal Heart Deceleration|Fetal Heart Rate Deceleration C90259 NICHD Pediatric Terminology C C92864 Prolonged Fetal Heart Rate Deceleration Prolonged Deceleration An extended decrease in the fetal heart rate compared to the normal baseline values. C92789 Fetal Heart Deceleration|Fetal Heart Rate Deceleration C92712 NICHD Pregnancy & Childbirth Terminology C C92866 Recurrent Fetal Heart Rate Deceleration Recurrent Deceleration A frequently repeated decrease in the fetal heart rate that occurs in conjunction with a uterine contraction; this happens with the majority of heartbeats. C92789 Fetal Heart Deceleration|Fetal Heart Rate Deceleration C90259 NICHD Pediatric Terminology C C92866 Recurrent Fetal Heart Rate Deceleration Recurrent Deceleration A frequently repeated decrease in the fetal heart rate that occurs in conjunction with a uterine contraction; this happens with the majority of heartbeats. C92789 Fetal Heart Deceleration|Fetal Heart Rate Deceleration C92712 NICHD Pregnancy & Childbirth Terminology C C92891 Subdermal Birth Control Implant Norplant Subdermal Birth Control Implant A subdermal implant incorporating silastic tubing containing levonorgestrel designed to administer a continuous dose of progestins for pregnancy contraception. A contraceptive device incorporating silastic tubing containing levonorgestrel designed to administer a continuous dose of progestins for pregnancy contraception, that is surgically placed under the skin C92759 Contraceptive Implant C90259 NICHD Pediatric Terminology C C92891 Subdermal Birth Control Implant Norplant Subdermal Birth Control Implant A subdermal implant incorporating silastic tubing containing levonorgestrel designed to administer a continuous dose of progestins for pregnancy contraception. A contraceptive device incorporating silastic tubing containing levonorgestrel designed to administer a continuous dose of progestins for pregnancy contraception, that is surgically placed under the skin C92759 Contraceptive Implant C92712 NICHD Pregnancy & Childbirth Terminology C C92913 Vaginal Bleeding during Pregnancy Vaginal Bleeding Hemorrhage from the vagina that may range from light spotting to heavy flow during pregnancy. C34941 Complication Related to Pregnancy|Pregnancy Complication C90259 NICHD Pediatric Terminology C C92913 Vaginal Bleeding during Pregnancy Vaginal Bleeding Hemorrhage from the vagina that may range from light spotting to heavy flow during pregnancy. C34941 Complication Related to Pregnancy|Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C92914 Variable Fetal Heart Rate Deceleration Variable Deceleration An irregular decrease in the fetal heart rate after the peak of an uterine contraction. C92789 Fetal Heart Deceleration|Fetal Heart Rate Deceleration C90259 NICHD Pediatric Terminology C C92914 Variable Fetal Heart Rate Deceleration Variable Deceleration An irregular decrease in the fetal heart rate after the peak of an uterine contraction. C92789 Fetal Heart Deceleration|Fetal Heart Rate Deceleration C92712 NICHD Pregnancy & Childbirth Terminology C C92931 Multiple Pregnancy Multiple Pregnancy A gestation with more than one fertilized egg implanted as a viable fetus in the uterus. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C C92931 Multiple Pregnancy Multiple Pregnancy A gestation with more than one fertilized egg implanted as a viable fetus in the uterus. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C C92939 Teenage Pregnancy Teenage Pregnancy A pregnancy in an adolescent between the ages of thirteen and nineteen. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C C92939 Teenage Pregnancy Teenage Pregnancy A pregnancy in an adolescent between the ages of thirteen and nineteen. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C C92948 Rh Factor Measurement Rh factor Measurement An immunology test to measure for the presence of the Rh factor antigen in blood. C98843 Blood Group Antibody Titer Measurement C90259 NICHD Pediatric Terminology C C92948 Rh Factor Measurement Rh factor Measurement An immunology test to measure for the presence of the Rh factor antigen in blood. C98843 Blood Group Antibody Titer Measurement C92712 NICHD Pregnancy & Childbirth Terminology C C96403 Measles/Mumps/Rubella Vaccine Measles Mumps Rubella Vaccine A trivalent vaccine containing live attenuated viruses that can cause measles, mumps and rubella. It is an injection administered subcutaneously in two separate doses. C1920 Attenuated Live Virus Vaccine C90259 NICHD Pediatric Terminology C C96403 Measles/Mumps/Rubella Vaccine Measles Mumps Rubella Vaccine A trivalent vaccine containing live attenuated viruses that can cause measles, mumps and rubella. It is an injection administered subcutaneously in two separate doses. C1920 Attenuated Live Virus Vaccine C96388 NICHD Childhood Immunization Terminology C C97109 Blindness Blindness The lack of vision. It is caused by neurological or physiological factors. C35126 Vision Disorder|Visual System Disorder C90259 NICHD Pediatric Terminology C C97109 Blindness Blindness The lack of vision. It is caused by neurological or physiological factors. C35126 Vision Disorder|Visual System Disorder C97150 NICHD Neurological Development Terminology C C97132 Chicken Pox Infection Chicken Pox A contagious childhood disorder caused by the varicella zoster virus. It is transmitted via respiratory secretions and contact with chickenpox blister contents. It presents with a vesicular skin rush, usually associated with fever, headache, and myalgias. The pruritic fluid-filled vesicles occur 10-21 days after exposure and last for 3-4 days. An additional 3-4 days of malaise follows before the affected individual feels better. An individual is contagious 1-2 days prior to the appearance of the blisters until all blisters are crusted over. Generally, healthy individuals recover without complications. C96411 Childhood Viral Disease C96407 Varicella-Zoster Virus Infection C90259 NICHD Pediatric Terminology C C97132 Chicken Pox Infection Chicken Pox A contagious childhood disorder caused by the varicella zoster virus. It is transmitted via respiratory secretions and contact with chickenpox blister contents. It presents with a vesicular skin rush, usually associated with fever, headache, and myalgias. The pruritic fluid-filled vesicles occur 10-21 days after exposure and last for 3-4 days. An additional 3-4 days of malaise follows before the affected individual feels better. An individual is contagious 1-2 days prior to the appearance of the blisters until all blisters are crusted over. Generally, healthy individuals recover without complications. C96411 Childhood Viral Disease C96407 Varicella-Zoster Virus Infection C96388 NICHD Childhood Immunization Terminology C C97151 Congenital Systemic Disorder Congenital Systemic Disorder An inherited disorder that presents with systemic manifestations. An inherited disorder that affects in multiple tissue types or in multiple organ systemsis, or affects the body as a whole. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology C C97160 Attention Deficit Hyperactivity Disorder Attention Deficit Hyperactivity Disorder A disorder characterized by a marked pattern of inattention and/or hyperactivity-impulsivity that is inconsistent with developmental level and clearly interferes with functioning in at least two settings (e.g. at home and at school). At least some of the symptoms must be present before the age of 7 years. C35470 Behavior Finding|Behavioral Disorder C90259 NICHD Pediatric Terminology C C97160 Attention Deficit Hyperactivity Disorder Attention Deficit Hyperactivity Disorder A disorder characterized by a marked pattern of inattention and/or hyperactivity-impulsivity that is inconsistent with developmental level and clearly interferes with functioning in at least two settings (e.g. at home and at school). At least some of the symptoms must be present before the age of 7 years. C35470 Behavior Finding|Behavioral Disorder C97150 NICHD Neurological Development Terminology C C97167 Anemia of Prematurity Anemia of Prematurity A blood disorder characterized by low hemoglobin levels in premature neonates that usually spontaneously resolves within 3-6 months post birth. A combination of factors including the transition from the liver to the bone marrow for erythropoiesis in a neonate, blood loss experienced during delivery, the shortened life span of fetal blood cells, and an acclimation to a relatively hyperoxic environment outside the womb can predispose a neonate to this condition. C61234 Congenital Hematological Disorder C90259 NICHD Pediatric Terminology C C97167 Anemia of Prematurity Anemia of Prematurity A blood disorder characterized by low hemoglobin levels in premature neonates that usually spontaneously resolves within 3-6 months post birth. A combination of factors including the transition from the liver to the bone marrow for erythropoiesis in a neonate, blood loss experienced during delivery, the shortened life span of fetal blood cells, and an acclimation to a relatively hyperoxic environment outside the womb can predispose a neonate to this condition. C61234 Congenital Hematological Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C97171 Congenital Gastrointestinal Disorder Congenital Abnormality of the Digestive System An abnormality of the digestive system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C2990 Digestive System Disorder|Gastrointestinal Disorder C90259 NICHD Pediatric Terminology C C97172 Congenital Nervous System Disorder Congenital Abnormality of the Nervous System An abnormality of the nervous system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C26835 Nervous System Disorder|Neurologic Disorder C90259 NICHD Pediatric Terminology C C97172 Congenital Nervous System Disorder Congenital Abnormality of the Nervous System An abnormality of the nervous system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C26835 Nervous System Disorder|Neurologic Disorder C97150 NICHD Neurological Development Terminology C C97173 Congenital Respiratory System Disorder Congenital Abnormality of the Respiratory System An abnormality of the respiratory system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C26871 Respiratory System Disorder C90259 NICHD Pediatric Terminology C C97174 Congenital Skin Disorder Congenital Abnormality of the Skin A skin abnormality that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C3371 Integumentary System Disorder|Skin Disorder C90259 NICHD Pediatric Terminology C C97175 Low Vision Low Vision Reduced ability to perceive visual stimuli. C35126 Vision Disorder|Visual System Disorder C90259 NICHD Pediatric Terminology C C97175 Low Vision Low Vision Reduced ability to perceive visual stimuli. C35126 Vision Disorder|Visual System Disorder C97150 NICHD Neurological Development Terminology C C97179 Pervasive Developmental Disorder Pervasive Developmental Disorder A category of developmental disorders characterized by impaired communication and socialization skills. The impairments are incongruent with the individual's developmental level or mental age. These disorders can be associated with general medical or genetic conditions. C96412 Brain Development Abnormality C90259 NICHD Pediatric Terminology C C97179 Pervasive Developmental Disorder Pervasive Developmental Disorder A category of developmental disorders characterized by impaired communication and socialization skills. The impairments are incongruent with the individual's developmental level or mental age. These disorders can be associated with general medical or genetic conditions. C96412 Brain Development Abnormality C97150 NICHD Neurological Development Terminology