NCIt Code NCIt PT NICHD PT NICHD SY NCIt Definition NICHD Definition NCIt Code of NICHD Parent NICHD Parent PT NCIt Code of second NICHD Parent NICHD second Parent PT NCIt Code of NICHD Subset NICHD PT of NICHD Subset C62651 Allergen Allergen A substance that elicits an allergic reaction. C45306 Substance C96388 NICHD Childhood Immunization Terminology C3114 Hypersensitivity Allergic Reaction A local or general reaction of an organism following contact with a specific allergen to which it has been previously exposed and to which it has become sensitized. C4876 Symptom C96388 NICHD Childhood Immunization Terminology C62761 Attenuated Bacteria Vaccine Attenuated Live Bacterial Vaccine Any vaccine created by reducing the virulence of bacteria but still keeping the bacteria viable (live). In the production of an attenuated vaccine, the infectious agent is altered so that it becomes harmless or less virulent. This is in contrast to those vaccines produced by "killing" the pathogen (inactivated vaccine). C97116 Attenuated Live Vaccine C96388 NICHD Childhood Immunization Terminology C97116 Attenuated Live Vaccine Attenuated Live Vaccine Any vaccine created by reducing the virulence of the infectious agent but still keeping the agent viable (live). In the production of an attenuated vaccine, the infectious agent is altered so that it becomes harmless or less virulent. This is in contrast to those vaccines produced by killing the pathogen (inactivated vaccine). C923 Vaccine C96388 NICHD Childhood Immunization Terminology C1920 Attenuated Live Virus Vaccine Attenuated Live Virus Vaccine Live vaccines prepared from microorganisms which have undergone physical adaptation (e.g., by radiation or temperature conditioning) or serial passage in laboratory animal hosts or infected tissue/cell cultures, in order to produce avirulent mutant strains capable of inducing protective immunity. Live-attenuated vaccines are used when a CD8+ T Cell (cellular cytotoxicity) response is desired. C97116 Attenuated Live Vaccine C96388 NICHD Childhood Immunization Terminology C2890 Bacterial Infection Bacterial Disease An acute infectious disorder caused by gram positive or gram negative bacteria. Representative examples include pneumococcal , streptococcal, salmonella and meningeal infections. C26726 Infectious Disease C96388 NICHD Childhood Immunization Terminology C76205 Bordetella pertussis Bordetella pertussis A species of bacteria within the phylum Proteobacteria consisting of gram-negative aerobic coccobacillus that are the causative agent of pertussis. C14187 Bacteria C96388 NICHD Childhood Immunization Terminology C9039 Cervical Carcinoma Cervical Carcinoma A carcinoma arising from either the exocervical squamous epithelium or the endocervical glandular epithelium. The major histologic types of cervical carcinoma are: squamous carcinoma, adenocarcinoma, adenosquamous carcinoma, adenoid cystic carcinoma and undifferentiated carcinoma. C3262 Neoplasm C96388 NICHD Childhood Immunization Terminology C3782 Cervical Intraepithelial Neoplasia Cervical Intraepithelial Neoplasia Squamous or glandular intraepithelial neoplasia that affects the cervical mucosal epithelium. There is no evidence of stromal invasion. According to the degree of cellular atypia and the associated architectural changes, it is classified as low or high grade. C3262 Neoplasm C96388 NICHD Childhood Immunization Terminology C97132 Chicken Pox Infection Chicken Pox A contagious childhood disorder caused by the varicella zoster virus. It is transmitted via respiratory secretions and contact with chickenpox blister contents. It presents with a vesicular skin rush, usually associated with fever, headache, and myalgias. The pruritic fluid-filled vesicles occur 10-21 days after exposure and last for 3-4 days. An additional 3-4 days of malaise follows before the affected individual feels better. An individual is contagious 1-2 days prior to the appearance of the blisters until all blisters are crusted over. Generally, healthy individuals recover without complications. C96411 Childhood Viral Disease C96388 NICHD Childhood Immunization Terminology C92915 Varicella Zoster Virus Immunization Chickenpox Immunization The administration of a live attenuated viral vaccine to prevent herpes zoster infection. C15258 Immunization C96388 NICHD Childhood Immunization Terminology C96411 Pediatric Viral Infection Childhood Viral Disease A viral infection that occurs during childhood. C89328 Pediatric Disease or Disorder C3439 Viral Disease C96388 NICHD Childhood Immunization Terminology C37928 Confusion Confusion A mental state characterized by a lack of clear and orderly thought and behavior. C4876 Symptom C96388 NICHD Childhood Immunization Terminology C1455 Conjugate Vaccine Conjugate Vaccine A category of vaccines created by covalently attaching an antigen from an organism to a carrier protein from the same organism to aid in the delivery of the immunogen. C97125 Polysaccharide Vaccine C96388 NICHD Childhood Immunization Terminology C3724 Cystic Hygroma Cystic Hygroma Cystic Lymphangioma A benign lymphatic neoplasm usually arising from the neck and characterized by cystic dilation of the lymphatic vessels. C2978 Cyst C96388 NICHD Childhood Immunization Terminology C27644 Deafness Deafness An inherited or acquired condition characterized by a partial or complete loss of hearing in one or both ears. The level of impairment varies from a mild but important loss of sensitivity to a total loss of hearing. C35731 Hearing Loss C96388 NICHD Childhood Immunization Terminology C9011 Dermoid Cyst Dermoid Cyst A mature teratoma characterized by the presence of a cyst which is lined by mature tissue resembling the epidermis and the epidermal appendages. It occurs in the ovary, testis, and extragonadal sites including central nervous system and skin. C2978 Cyst C96388 NICHD Childhood Immunization Terminology C2987 Diarrhea Diarrhea A condition of frequent and watery bowel movements. C4876 Symptom C96388 NICHD Childhood Immunization Terminology C34541 Diphtheria Diphtheria A Gram-positive bacterial infection caused by Corynebacterium diphtheria. It usually involves the oral cavity, pharynx, and nasal cavity. Patients develop pseudomembranes in the affected areas and manifest signs and symptoms of an upper respiratory infection. The diphtheria toxin may cause myocarditis, polyneuritis, and other systemic effects. C2890 Bacterial Disease C96388 NICHD Childhood Immunization Terminology C91718 Diphtheria Toxoid/Tetanus Toxoid Vaccine Adsorbed Diphtheria Toxoid/Tetanus Toxoid Vaccine Adsorbed A vaccine containing detoxified tetanus toxoid and detoxified diphtheria toxoid adsorbed on aluminum phosphate with active immunizing activity against diphtheria and tetanus. Intramuscular injection with this vaccine activates the immune system to develop antibodies against tetanus toxin and diphtheria toxin. C96398 Toxoid Vaccine C96388 NICHD Childhood Immunization Terminology C91717 Diphtheria Toxoid/Tetanus Toxoid/Acellular Pertussis Vaccine Adsorbed Diphtheria Toxoid/Tetanus Toxoid/Acellular Pertussis Vaccine DTP vaccine A vaccine containing detoxified tetanus toxoid, detoxified diphtheria toxoid and acellular pertussis antigens, adsorbed on aluminum phosphate, with active immunizing activity against diphtheria, tetanus and pertussis. The acellular pertussis vaccine components, produced by Bordetella pertussis, are detoxified pertussis toxin (PT), filamentous hemagglutinin (FHA), pertactin (PRN) and fimbriae types 2 and 3 (FIM). Intramuscular injection with this vaccine activates the immune system to develop antibodies against tetanus toxin, diphtheria toxin and B. pertussis antigens. C2848 Polyvalent Vaccine C96388 NICHD Childhood Immunization Terminology C97122 Diphtheria Toxoid/Tetanus Toxoid/Inactivated Pertussis Vaccine Diphtheria Toxoid/Tetanus Toxoid/Inactivated Pertussis Vaccine DTP A vaccine containing detoxified tetanus toxoid, detoxified diphtheria toxoid and inactivated pertussis antigens. C2848 Polyvalent Vaccine C96388 NICHD Childhood Immunization Terminology C3038 Fever Fever The elevation of the body's temperature above the upper limit of normal, usually taken as 37.7 degrees C. C4876 Symptom C96388 NICHD Childhood Immunization Terminology C2960 Condyloma Acuminatum Genital Warts Condyloma Acuminatum A sexually transmitted papillary growth caused by the human papillomavirus. It usually arises in the skin and mucous membranes of the perianal region and external genitalia. C3439 Viral Disease C96388 NICHD Childhood Immunization Terminology C80444 H1N1 Influenza H1N1 Influenza Swine flu An acute viral respiratory infection caused by a strain of influenza virus which is endemic in swine (pigs). Rarely reported in humans prior to 2009, the disease is caused by a mutated strain of swine influenza A (H1N1) virus. It is highly contagious and spreads mainly through coughing and sneezing. Signs and symptoms include fever, chills, coughing, sore throat headache, muscle ache, and generalized weakness. Antiviral medications are most effective in the first two days of the illness. C53482 Influenza C96388 NICHD Childhood Immunization Terminology C1126 Haemophilus Influenzae B Vaccine Haemophilus Influenzae B Vaccine Hib Vaccine|PRP vaccine A vaccine against serotype b of the Gram-negative bacterium H. influenzae (Hib). Hib vaccines contain polysaccharide-protein conjugate antigens that produce greater host immune responses than first-generation purified polysaccharide vaccine. These vaccines may differ with regard to use of protein carriers, polysaccharides, diluents, and preservatives. C1455 Conjugate Vaccine C96388 NICHD Childhood Immunization Terminology C3096 Hepatitis A Infection Hepatitis A Acute inflammation of the liver caused by the hepatitis A virus. It is highly contagious and usually contracted through close contact with an infected individual or their feces, contaminated food or water. C3439 Viral Disease C96388 NICHD Childhood Immunization Terminology C29090 Hepatitis A Vaccine Hepatitis A Vaccine An inactivated virus vaccine that provides active immunization against hepatitis A virus (HAV). Immunization with hepatitis A vaccine induces the formation of anti-HAV antibodies which provide protection against hepatitis A infection. C29694 Inactivated Vaccine C96388 NICHD Childhood Immunization Terminology C3097 Hepatitis B Infection Hepatitis B A viral infection caused by the hepatitis B virus. C3439 Viral Disease C96388 NICHD Childhood Immunization Terminology C14226 Human Papillomavirus Human Papilloma Virus A strain of papillomavirus that can infect the skin and mucous membranes of humans. C14283 Virus C96388 NICHD Childhood Immunization Terminology C14338 Human Papillomavirus-16 Human Papillomavirus-16 A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce skin and mucosal epithelial lesions. Human papillomavirus-16 (HPV16) has been directly linked to cervical cancer and is significantly associated with invasiveness. Progression from low- to high-grade neoplasia is often associated with the integration of the HPV16 genome into the host chromosome. C14226 Human Papilloma Virus C96388 NICHD Childhood Immunization Terminology C14377 Human Papillomavirus-18 Human Papillomavirus-18 A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce skin and mucosal epithelial lesions. Human papillomavirus-18 (HPV18) has been directly linked to cervical cancer and plays a role in the pathogenesis of the disease. The virus integrates its DNA at specific chromosomal locations, such as 8q24 and 12q15. The use of molecular markers for HPV18 infection may allow the identification of patients with early stage cervical cancer and those at high risk for disease recurrence. C14226 Human Papilloma Virus C96388 NICHD Childhood Immunization Terminology C15258 Immunization Immunization Inoculating an individual with either killed or live agents to prevent contraction of a disease. C15843 Preventive Intervention C96388 NICHD Childhood Immunization Terminology C91715 Inactivated Poliovirus Vaccine Inactivated Poliovirus Vaccine A vaccine consisting of inactivated poliovirus (IPV) types 1,2 and 3, with active immunizing activity against poliomyelitis. Upon intramuscular vaccination, inactivated poliovirus vaccine (IPV) activates the immune system to develop antibodies against polioviruses. C29694 Inactivated Vaccine C96388 NICHD Childhood Immunization Terminology C29694 Inactivated Vaccine Inactivated Vaccine A preparation of killed microorganisms that is intended to prevent or treat an infectious disease by inducing active immunity to the causative microorganism. C923 Vaccine C96388 NICHD Childhood Immunization Terminology C26726 Infectious Disorder Infectious Disease A disorder resulting from the presence and activity of a microbial, viral, or parasitic agent. It can be transmitted by direct or indirect contact. C2991 Disease or Disorder C96388 NICHD Childhood Immunization Terminology C53482 Influenza Influenza Flu An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system. C3439 Viral Disease C96388 NICHD Childhood Immunization Terminology C96408 Influenza Vaccination Influenza Vaccination The administration of live or attenuated influenza virus for the prophylaxis of influenza. C15258 Immunization C96388 NICHD Childhood Immunization Terminology C96402 Live Attenuated Influenza Vaccine Live Attenuated Influenza Vaccine Nasal Spray Flu Vaccine A vaccine that contains live attenuated influenza virus (LAIV) particles. This vaccine is administered intranasally for influenza prophylaxis. Not all populations are good candidates for LAIV; the very young, elderly, asthmatics and those with health impaired may be better treated with the trivalent inactivated vaccine that is administered intramuscularly. C1920 Attenuated Live Virus Vaccine C96388 NICHD Childhood Immunization Terminology C34797 Malaria Malaria A protozoan infection caused by the genus Plasmodium. There are four species of Plasmodium that can infect humans: Plasmodium falciparum, vivax, ovale, and malariae. It is transmitted to humans by infected mosquitoes. Signs and symptoms include paroxysmal high fever, sweating, chills, and anemia. C27864 Parasitic Disease C96388 NICHD Childhood Immunization Terminology C96406 Rubeola Infection Measles Rubeola A highly contagious viral infection caused by the measles virus. Symptoms appear 8-12 days after exposure and include a rash, cough, fever and muscle pains that can last 4-7 days. Measles vaccines are available to provide prophylaxis, usually combined with mumps and rubella vaccines (MMR). C96411 Childhood Viral Disease C96388 NICHD Childhood Immunization Terminology C96403 Measles/Mumps/Rubella Vaccine Measles Mumps Rubella Vaccine A trivalent vaccine containing live attenuated viruses that can cause measles, mumps and rubella. It is an injection administered subcutaneously in two separate doses. C1920 Attenuated Live Virus Vaccine C96388 NICHD Childhood Immunization Terminology C26828 Meningitis Meningitis A disorder characterized by acute inflammation of the meninges of the brain and/or spinal cord. C26726 Infectious Disease C96388 NICHD Childhood Immunization Terminology C96391 Meningococcal Conjugate Vaccine MCV4 Meningococcal Conjugate Vaccine MCV-4 A conjugate vaccine of meningococcal polysaccharide used for active immunization against invasive meningococcal disease caused by Neisseria meningiditis serogroups A, C, Y, and W-135. C1455 Conjugate Vaccine C96388 NICHD Childhood Immunization Terminology C96519 Meningococcal Polysaccharide Vaccine MPSV4 Meningococcal Polysaccharide Vaccine MPSV-4 A polysaccharide vaccine used to prevent contraction of meningococcal meningitis. C97125 Polysaccharide Vaccine C96388 NICHD Childhood Immunization Terminology C84392 Mental Retardation Mental Retardation A developmental disorder characterized by less than average intelligence and significant limitations in adaptive behavior with onset before the age of 18. C92190 Childhood Mental Disorder C96388 NICHD Childhood Immunization Terminology C29888 Mumps Mumps A contagious viral infection caused by the mumps virus. Symptoms include swollen and tender parotid glands, fever, muscle aches and fatigue. Due to vaccination programs, mumps has become a rare disease. C96411 Childhood Viral Disease C96388 NICHD Childhood Immunization Terminology C86605 Neisseria meningitidis Neisseria meningitidis A gram negative diplococcal bacterium that is a causative agent for meningitis and other meningococcal diseases. C14187 Bacteria C96388 NICHD Childhood Immunization Terminology C96401 Oral Polio Vaccine Oral Polio Vaccine A vaccine that contains live attenuated polio virus. It is administered orally as polio prophylaxis in many areas of the world, but not in the U.S. since 2000. C1920 Attenuated Live Virus Vaccine C96388 NICHD Childhood Immunization Terminology C3303 Pain Pain The sensation of discomfort, distress, or agony, resulting from the stimulation of specialized nerve endings. C4876 Symptom C96388 NICHD Childhood Immunization Terminology C27864 Parasitic Infection Parasitic Disease A successful invasion of a host by an organism that uses the host for food and shelter. C26726 Infectious Disease C96388 NICHD Childhood Immunization Terminology C1909 Pharmacologic Substance Pharmacologic Substance An active natural, synthetic or semi-synthetic ingredient including endogenous body substance that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the human body, but does not include intermediates used in the synthesis of such ingredient (21 CFR 314.3(b)). C45306 Substance C96388 NICHD Childhood Immunization Terminology C97120 Pneumococcal 10-valent Conjugate Vaccine Pneumococcal 10-valent Conjugate Vaccine An active immunizing vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. It is indicated for disease caused by serotypes 1, 5, 4, 6B, 7, 9V, 14, 18C, 19F, and 23F. C97123 Pneumococcal Conjugate Vaccine C96388 NICHD Childhood Immunization Terminology C97121 Pneumococcal 13-valent Conjugate Vaccine Pneumococcal 13-valent Conjugate Vaccine An active immunizing vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. It is indicated for disease caused by serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F. It can also be used to prevent against otitis media by serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F. C97123 Pneumococcal Conjugate Vaccine C96388 NICHD Childhood Immunization Terminology C1643 Pneumococcal Polyvalent Vaccine Pneumococcal 23-valent Polysaccharide Vaccine An polyvalent vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. Pneumococcal polyvalent vaccine contains highly purified capsular antigens from the 23 most prevalent or invasive pneumococcal types of Streptococcus pneumoniae to ensure cross-protection. Following vaccination, protective capsular type-specific antibody levels typically develop by the third week; serotype-specific antibody levels generally decline after 5-10 years. C97125 Polysaccharide Vaccine C96388 NICHD Childhood Immunization Terminology C38141 Pneumococcal 7-Valent Conjugate Vaccine Pneumococcal 7-Valent Conjugate Vaccine An active immunizing agent used to prevent infection by the bacterium Streptococcus pneumoniae. Pneumococcal 7-valent conjugate vaccine consists of a solution of saccharides of the capsular antigens of Streptococcus serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F individually conjugated to diphtheria CRM 197 protein. C97123 Pneumococcal Conjugate Vaccine C96388 NICHD Childhood Immunization Terminology C97123 Pneumococcal Conjugate Vaccine Pneumococcal Conjugate Vaccine An active immunizing vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. It consists of a solution of saccharides of the capsular antigens of Streptococcus serotypes individually conjugated to proteins. C1455 Conjugate Vaccine C96388 NICHD Childhood Immunization Terminology C3333 Pneumonia Pneumonia An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, due to infections (viruses, fungi, mycoplasma, or bacteria), treatment (e.g. radiation), or exposure (inhalation) to chemicals. Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness. C26871 Respiratory System Disorder C96388 NICHD Childhood Immunization Terminology C96409 Polio Vaccination Polio Vaccination The administration a series of either live or inactivated poliovirus for the prophylaxis of poliomyelitis. C15258 Immunization C96388 NICHD Childhood Immunization Terminology C35550 Acute Poliomyelitis Poliomyelitis Polio An acute infectious disorder that affects the nervous system. It is caused by the poliovirus. The virus spreads by direct contact, and can be prevented by prophylaxis with the polio vaccine. C96411 Childhood Viral Disease C96388 NICHD Childhood Immunization Terminology C14259 Poliovirus Poliovirus An enterovirus comprised of an single-stranded positive sense RNA genome and a protein capsid. This virus is the human pathogen that causes poliomyelitis. C14283 Virus C96388 NICHD Childhood Immunization Terminology C97125 Polysaccharide Vaccine Polysaccharide Vaccine A category of vaccines that use the extracted and purified outer polysaccharide coat of the particular bacteria. C923 Vaccine C96388 NICHD Childhood Immunization Terminology C2848 Polyvalent Vaccine Polyvalent Vaccine A vaccine designed to elicit an immune response either to more than one infectious agent or to several different antigenic determinants of a single agent. C923 Vaccine C96388 NICHD Childhood Immunization Terminology C29091 Hepatitis B Vaccine Recombinant Hepatitis B Vaccine A non-infectious mixture containing recombinant hepatitis B surface antigen (HBsAg) in a liquid vehicle. Immunization with the hepatitis B vaccine induces the formation of specific anti-hepatitis B antibodies and an active immunity against hepatitis B infection. C1572 Recombinant Viral Vaccine C96388 NICHD Childhood Immunization Terminology C1951 Human Papilloma Virus Vaccine Recombinant Human Papilloma Virus Vaccine A recombinant vaccine of different types of HPV proteins which are well-conserved within types with a significant inter-type variation. C1572 Recombinant Viral Vaccine C96388 NICHD Childhood Immunization Terminology C1572 Recombinant Viral Vaccine Recombinant Viral Vaccine A vaccine produced from genetically engineered viral vector by introduction of foreign genetic materials to activate immune response in a host. C923 Vaccine C96388 NICHD Childhood Immunization Terminology C4077 Redness Redness Coloration of the skin; sign of inflammation C4876 Symptom C96388 NICHD Childhood Immunization Terminology C92947 Rh Immune Globulin Administration Rh Immune Globulin Administration Rho(D) Immune Globulin Administration The administration of Rh Immune Globulin to a pregnant mother to ameliorate the effects of conflicting Rh factors during pregnancy. C15843 Preventive Intervention C96388 NICHD Childhood Immunization Terminology C77199 Rotavirus Rotavirus A genus of double stranded RNA viruses that carry 11 unique double helix molecules of RNA that encode one or two proteins each. The RNA is surrounded by a three-layered icosahedral protein capsid. Viral particles are up to 76.5 nm in diameter and are not enveloped. C14283 Virus C96388 NICHD Childhood Immunization Terminology C96394 Rotavirus Vaccine Rotavirus Vaccine A viral vaccine that prevents against rotavirus infection, the leading cause of severe acute gastroenteritis. C1920 Attenuated Live Virus Vaccine C96388 NICHD Childhood Immunization Terminology C92872 Rubella Immunization Rubella Immunization The administration of a live attenuated viral vaccine to prevent rubella infection. C15258 Immunization C96388 NICHD Childhood Immunization Terminology C85051 Rubella Infection Rubella Infection German Measles A viral infection caused by the rubella virus. It is initially manifested with flu-like symptoms that last one or two days, followed by the development of a characteristic red rash which lasts from one to five days. The rash first appears in the neck and face. It subsequently spreads to the rest of the body. C3439 Viral Disease C96388 NICHD Childhood Immunization Terminology C39594 Skin Rash Skin Rash Any change in the skin which affects its appearance or texture. A rash may be localized to one part of the body, or affect all the skin. Rashes may cause the skin to change color, itch, become warm, bumpy, dry, cracked or blistered, swell and may be painful. C4876 Symptom C96388 NICHD Childhood Immunization Terminology C85185 Tetanus Tetanus A serious infectious disorder that follows wound contamination by the Gram-positive bacterium Clostridium tetani. The bacteria produce a neurotoxin called tetanospasmin, which causes muscle spasm in the jaw and other anatomic sites. C2890 Bacterial Disease C96388 NICHD Childhood Immunization Terminology C96405 Tetanus and Diphtheria Toxoids Adsorbed Tetanus and Diphtheria Toxoids Adsorbed A sterile, intramuscular suspension of alum (aluminum potassium sulfate)-precipitated toxoids indicated for active immunization for the prevention of tetanus and diphtheria for use in persons 7 years of age or older. C96398 Toxoid Vaccine C96388 NICHD Childhood Immunization Terminology C2660 Tetanus Toxoid Vaccine Tetanus Toxoid Vaccine A preparation of formaldehyde-deactivated toxin isolated from the bacterium Clostridium tetani. Tetanus toxoid is used for booster injection and can stimulate the production of antitoxin antibodies. This agent may be used as an adjuvant in cancer vaccines. C96398 Toxoid Vaccine C96388 NICHD Childhood Immunization Terminology C96398 Toxoid Vaccine Toxoid Vaccine Any vaccine that contains an inactivated toxic substance used for disease prophylaxis or to vaccinate against snake bites. C923 Vaccine C96388 NICHD Childhood Immunization Terminology C2643 Trivalent Influenza Vaccine Trivalent Influenza Vaccine Flu prevention|Flu prophylaxis|Flu shot|Flu vaccination A synthetic vaccine consisting of three inactivated influenza viruses, two different influenza type A strains and one influenza type B strain. Trivalent influenza vaccine is formulated annually, based on influenza strains projected to be prevalent in the upcoming flu season. This agent may be formulated for injection or intranasal administration. C2848 Polyvalent Vaccine C96388 NICHD Childhood Immunization Terminology C97126 Ty21a Typhoid Vaccine Ty21a Typhoid Vaccine A live attenuated oral virus vaccine used to prevent typhoid, which is caused by Salmonella typhi. C62761 Attenuated Live Bacterial Vaccine C96388 NICHD Childhood Immunization Terminology C35089 Typhoid Fever Typhoid Fever A bacterial infectious disorder contracted by consumption of food or drink contaminated with Salmonella typhi. This disorder is common in developing countries and can be treated with antibiotics. C2890 Bacterial Disease C96388 NICHD Childhood Immunization Terminology C923 Vaccine Vaccine Preparations containing substances with antigenic properties administered to activate the immune system, thereby inducing an immune response. Vaccines range from inactivated or attenuated microorganisms (bacteria and viruses), enhanced autologous tumor cells, tumor antigens or epitopes that are used to elicit host immune responses. Vaccines are used for the prevention, amelioration, or treatment of infectious diseases and cancer. C307 Biologic Agent C96388 NICHD Childhood Immunization Terminology C96395 Varicella Vaccine Varicella Vaccine Chickenpox Vaccine|Shingles Vaccine A live attenuated virus vaccine used to prevent chickenpox and shingles, which is caused by varicella-zoster virus (VZV). C1920 Attenuated Live Virus Vaccine C96388 NICHD Childhood Immunization Terminology C71091 Human Herpesvirus 3 Varicella-Zoster Virus An icosahedral, enveloped virus containing a single molecule of linear double-stranded DNA of 125000 nucleotides that infects only humans. It is the causative agent of chickenpox and shingles. C14283 Virus C96388 NICHD Childhood Immunization Terminology C97127 Vi Capsular Polysaccharide Typhoid Vaccine Vi Capsular Polysaccharide Typhoid Vaccine A live attenuated injectable virus vaccine used to prevent typhoid, which is caused by Salmonella typhi. C97125 Polysaccharide Vaccine C96388 NICHD Childhood Immunization Terminology C3439 Viral Infection Viral Disease Viral Infection Any disease caused by a virus. C26726 Infectious Disease C96388 NICHD Childhood Immunization Terminology C3442 Vomiting Vomiting The reflex act of ejecting the contents of the stomach through the mouth. C4876 Symptom C96388 NICHD Childhood Immunization Terminology C96396 Yellow Fever Vaccine Yellow Fever Vaccine A live, attenuated viral vaccine to prevent yellow fever, endemic to parts of Africa and South America. C1920 Attenuated Live Virus Vaccine C96388 NICHD Childhood Immunization Terminology C35547 Yellow Fever Virus Infection Yellow Fever Virus Infection A viral infection caused by a flavivirus called yellow fever virus. It is transmitted to humans from infected mosquitoes. The signs and symptoms range from a mild febrile illness to liver damage with jaundice and hemorrhages. C3439 Viral Disease C96388 NICHD Childhood Immunization Terminology C92621 Acute Stress Disorder Acute Stress Disorder An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by dissociative symptoms; vivid recollections of the traumatic event; avoidance of stimuli associated with the traumatic event; and a constant state of hyperarousal for no more than one month. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology C34362 Agoraphobia Agoraphobia An anxiety disorder characterized by an intense, irrational fear of venturing out into open places or situations in which help (or escape) might not be available should excessive anxiety or panic symptoms develop. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology C34387 Anorexia Nervosa Anorexia Nervosa A disorder most often seen in adolescent females characterized by a refusal to maintain a minimally normal body weight, an intense fear of gaining weight, a disturbance in body image, and, in postmenarcheal females, the development of amenorrhea. C89332 Eating Disorder C97150 NICHD Neurological Development Terminology C2878 Anxiety Disorder Anxiety Disorder A category of psychiatric disorders which are characterized by anxious feelings or fear often accompanied by physical symptoms associated with anxiety. C2893 Psychiatric Disorder C97150 NICHD Neurological Development Terminology C97159 Asperger Syndrome Asperger Syndrome A disorder most often diagnosed in the pediatric years in which the individual displays marked impairment in social interaction and a repetitive, stereotyped pattern of behavior. The individual, however, displays no delay in language or cognitive development, which differentiates Asperger Syndrome from autism. C88412 Autism Spectrum Disorder C97150 NICHD Neurological Development Terminology C97168 Ataxic Cerebral Palsy Ataxic Cerebral Palsy The least common subtype of cerebral palsy, in which the individual displays hypotonia, a loss of motor coordination, and an intention tremor. Individuals with ataxic cerebral palsy walk very unsteadily, with a wide-based gait. C34460 Cerebral Palsy C97150 NICHD Neurological Development Terminology C97169 Athetoid Cerebral Palsy Athetoid Cerebral Palsy A subtype of cerebral palsy characterized by involuntary, purposeless writhing movements which affect the hands, feet, arms, and legs; the face and tongue may be affected as well, leading to involuntary grimacing, drooling, dysarthria and difficulty eating. C34460 Cerebral Palsy C97150 NICHD Neurological Development Terminology C97160 Attention Deficit Hyperactivity Disorder Attention Deficit Hyperactivity Disorder A disorder characterized by a marked pattern of inattention and/or hyperactivity-impulsivity that is inconsistent with developmental level and clearly interferes with functioning in at least two settings (e.g. at home and at school). At least some of the symptoms must be present before the age of 7 years. C35470 Behavioral Disorder C97150 NICHD Neurological Development Terminology C97161 Autism Autism A disorder characterized by marked impairments in social interaction and communication accompanied by a pattern of repetitive, stereotyped behaviors and activities. Developmental delays in social interaction and language surface prior to age 3 years. C88412 Autism Spectrum Disorder C97150 NICHD Neurological Development Terminology C88412 Autism Spectrum Disorder Autism Spectrum Disorder A spectrum of developmental disorders that includes autism, Asperger syndrome, and Rett syndrome. Signs and symptoms include poor communication skills, defective social interactions, and repetitive behaviors. C97179 Pervasive Developmental Disorder C97150 NICHD Neurological Development Terminology C35470 Behavior-Related Disorder Behavioral Disorder A specific behavioral problem that occurs in persistent patterns and characteristic clusters and that causes clinically significant impairment. C2991 Disease or Disorder C97150 NICHD Neurological Development Terminology C97162 Binge Eating Disorder Binge Eating Disorder A disorder characterized by recurrent episodes of binge-eating over which the individual feels a lack of control and a sense of disgust and shame; unlike bulimia, however, there is no attempt to compensate for the binge-eating through vomiting or fasting. C89332 Eating Disorder C97150 NICHD Neurological Development Terminology C34423 Bipolar Disorder Bipolar Disorder A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence. C2893 Psychiatric Disorder C97150 NICHD Neurological Development Terminology C97109 Blindness Blindness The lack of vision. It is caused by neurological or physiological factors. C35126 Vision Disorder C97150 NICHD Neurological Development Terminology C96412 Brain Developmental Abnormality Brain Development Abnormality A group of congenital or acquired disorders that affect the normal development of the brain. C89338 Neurodevelopmental Disorder C97150 NICHD Neurological Development Terminology C96413 Brain Disorder Brain Disorder A non-neoplastic or neoplastic disorder that affects the brain. C2934 Central Nervous System Disorder C97150 NICHD Neurological Development Terminology C34440 Bulimia Bulimia Nervosa A disorder characterized by recurrent episodes of binge-eating over which the individual feels a lack of control; these episodes of binge-eating are followed by recurrent compensatory behavior to prevent weight gain, usually self-induced vomiting. In addition, self-evaluation is unduly influenced by body image. C89332 Eating Disorder C97150 NICHD Neurological Development Terminology C97170 Central Auditory Processing Disorder Central Auditory Processing Disorder A disorder characterized by impairment of the auditory processing, resulting in deficiencies in the recognition and interpretation of sounds by the brain. Causes include brain maturation delays and brain traumas or tumors. C97155 Language Disorder C97150 NICHD Neurological Development Terminology C34662 Central Hearing Loss Central Hearing Loss Hearing loss caused by a problem along the pathway from the inner ear to the auditory region of the brain or in the brain itself. C35731 Hearing Loss C97150 NICHD Neurological Development Terminology C2934 Central Nervous System Disorder Central Nervous System Disorder A non-neoplastic or neoplastic disorder which affects the brain and/or spinal cord. C26835 Neurologic Disorder C97150 NICHD Neurological Development Terminology C34460 Cerebral Palsy Cerebral Palsy A group of disorders affecting the development of movement and posture, often accompanied by disturbances of sensation, perception, cognition, and behavior. It results from damage to the fetal or infant brain. C26835 Neurologic Disorder C89328 Pediatric Disease or Disorder C97150 NICHD Neurological Development Terminology C97163 Childhood Depression Childhood Depression Similar to depression in adults, childhood depression is characterized by a prolonged depressed or irritable mood accompanied by a significant loss of interest in activities, changes in appetite or sleep, decreased energy, feelings of worthlessness, and/or recurrent thoughts of death or suicide. C92190 Childhood Mental Disorder C97150 NICHD Neurological Development Terminology C97164 Childhood Disintegrative Disorder Childhood Disintegrative Disorder A pediatric disorder characterized by normal development for at least the first two years of life followed by a severe regression in language, social interaction, bowel or bladder control, and/or motor skills. The affected individual may also exhibit repetitive and stereotyped patterns of behavior similar to autism. C97179 Pervasive Developmental Disorder C97150 NICHD Neurological Development Terminology C92190 Pediatric Psychiatric Disorder Childhood Mental Disorder A category of psychiatric disorders which includes disorders most commonly identified in infancy, childhood, or adolescence. C89328 Pediatric Disease or Disorder C97150 NICHD Neurological Development Terminology C35004 Childhood Schizophrenia Childhood Schizophrenia Schizophrenia occurring in childhood. C92190 Childhood Mental Disorder C97150 NICHD Neurological Development Terminology C27645 Conductive Hearing Loss Conductive Hearing Loss Hearing loss caused by a problem in the outer ear or middle ear. Conductive losses usually affect all frequencies to the same degree. These losses are not usually severe. C35731 Hearing Loss C97150 NICHD Neurological Development Terminology C35107 Congenital Genitourinary Abnormality Congenital Abnormality of the Genitourinary System An abnormality of the genitourinary system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C97150 NICHD Neurological Development Terminology C97172 Congenital Nervous System Disorder Congenital Abnormality of the Nervous System An abnormality of the nervous system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C97150 NICHD Neurological Development Terminology C34527 Demyelinating Disorder Demyelinating Disorder A broad group of disorders that affect the myelin sheaths that cover the neurons. Myelin sheathes cover neuronal axons in the central and peripheral nervous system and function to increase travelling impulse speeds. Disruption of this sheath impairs neuronal transmission and can result in disorders such as multiple sclerosis and Guillain-Barre syndrome, among others. C26835 Neurologic Disorder C97150 NICHD Neurological Development Terminology C92561 Developmental Coordination Disorder Developmental coordination disorder Developmental Dyspraxia A disorder characterized by an impairment in the development of an individual's motor coordination skills; this impairment in motor development is not due to a medical condition. C89338 Neurodevelopmental Disorder C92190 Childhood Mental Disorder C97150 NICHD Neurological Development Terminology C97165 Dyscalculia Dyscalculia A wide group of related learning disorders characterized by difficulties with mathematics and manipulating numbers; the difficulty with math may be caused or exacerbated by visuo-spatial or language processing difficulties. C89334 Learning Disorder C97150 NICHD Neurological Development Terminology C96410 Dyslexia Dyslexia A learning disorder characterized by an impairment in processing written words. Reading difficulties can include distortions, omissions or substitutions of characters. Oral and silent reading difficulties can include faulty and slow comprehension. C89334 Learning Disorder C97150 NICHD Neurological Development Terminology C89332 Eating Disorder Eating Disorder A broad group of psychological disorders with abnormal eating behaviors leading to physiological effects from overeating or insufficient food intake. C2893 Psychiatric Disorder C97150 NICHD Neurological Development Terminology C97166 Echolalia Echolalia A symptom of neurologic or psychiatric dysfunction in which the individual involuntarily and meaninglessly repeats a recently heard word, series of words, or a song. C97170 Central Auditory Processing Disorder C97150 NICHD Neurological Development Terminology C26920 Encephalopathy Encephalopathy A functional and/or structural disorder of the brain caused by diseases (e.g. liver disease, kidney disease), medications, chemicals, and injuries. C96413 Brain Disorder C97150 NICHD Neurological Development Terminology C3020 Epilepsy Epilepsy A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions. C96413 Brain Disorder C97150 NICHD Neurological Development Terminology C92622 Generalized Anxiety Disorder Generalized Anxiety Disorder An anxiety disorder characterized by excessive and difficult-to-control worry about a number of life situations. The worry is accompanied by restlessness, fatigue, inability to concentrate, irritability, muscle tension, and/or sleep disturbance and lasts for at least 6 months. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology C35731 Hearing Loss Hearing Loss A partial or complete loss of hearing in one or both ears. It is classified as conductive, sensory, or central. C63711 Sensory Disorder C97150 NICHD Neurological Development Terminology C97250 Intellectual Disability Intellectual Disabilities A broad category of disorders characterized by an impairment to the intelligence an individual possesses. These impairments can result from trauma, birth or disease and are not restricted to any particular age group. C96413 Brain Disorder C97150 NICHD Neurological Development Terminology C50896 Intraventricular Brain Hemorrhage Intraventricular Hemorrhage Bleeding into the brain's ventricles. C2931 Cardiovascular Disorder C97150 NICHD Neurological Development Terminology C97155 Language Disorder Language Disorder A category of disorders characterized by an impairment in the development of an individual's language capabilities, which is in contrast to his/her non-verbal intellect. C92190 Childhood Mental Disorder C97150 NICHD Neurological Development Terminology C97175 Low Vision Low Vision Reduced ability to perceive visual stimuli. C35126 Vision Disorder C97150 NICHD Neurological Development Terminology C84392 Mental Retardation Mental Retardation A developmental disorder characterized by less than average intelligence and significant limitations in adaptive behavior with onset before the age of 18. C92190 Childhood Mental Disorder C97150 NICHD Neurological Development Terminology C97177 Mixed Cerebral Palsy Mixed Cerebral Palsy A subtype of cerebral palsy characterized by both the tight muscle tone of spastic cerebral palsy and the writhing, involuntary muscle movements of athetoid cerebral palsy. C34460 Cerebral Palsy C97150 NICHD Neurological Development Terminology C97178 Mixed Hearing Loss Mixed Hearing Loss A combination of conductive and sensorineural losses. C35731 Hearing Loss C97150 NICHD Neurological Development Terminology C26835 Nervous System Disorder Neurologic Disorder A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves. C2991 Disease or Disorder C97150 NICHD Neurological Development Terminology C88411 Obsessive Compulsive Disorder Obsessive-Compulsive Disorder A disorder characterized by the presence of persistent and recurrent irrational thoughts (obsessions), resulting in marked anxiety and repetitive excessive behaviors (compulsions) as a way to try to decrease that anxiety. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology C97194 Panic Disorder with Agoraphobia Panic Disorder with Agoraphobia A disorder in which an individual experiences recurrent, unexpected panic attacks and persistent concern about having additional panic attacks. Agoraphobia is a component of this disorder. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology C97193 Panic Disorder without Agoraphobia Panic Disorder without Agoraphobia A disorder in which an individual experiences recurrent, unexpected panic attacks and persistent concern about having additional panic attacks. Agoraphobia is not a component of this disorder. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology C97179 Pervasive Developmental Disorder Pervasive Developmental Disorder A category of developmental disorders characterized by impaired communication and socialization skills. The impairments are incongruent with the individual's developmental level or mental age. These disorders can be associated with general medical or genetic conditions. C96412 Brain Development Abnormality C89338 Neurodevelopmental Disorder C97150 NICHD Neurological Development Terminology C3389 Post-Traumatic Stress Disorder Post-Traumatic Stress Disorder An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by intrusive recurring thoughts or images of the traumatic event; avoidance of anything associated with the event; a state of hyperarousal and diminished emotional responsiveness. These symptoms are present for at least one month and the disorder is usually long-term. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology C75488 Rett Syndrome Rett Syndrome A progressive neurologic disorder caused by mutations in the MECP2 gene on chromosome X. It almost exclusively affects girls. It is characterized by language and learning difficulties, poor communication skills, and repetitive hand motions. Other signs and symptoms include microcephaly, scoliosis, breathing abnormalities, and sleep disturbances. C97179 Pervasive Developmental Disorder C97150 NICHD Neurological Development Terminology C2962 Seizure Seizure Sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin. C4876 Symptom C97150 NICHD Neurological Development Terminology C92569 Selective Mutism Selective Mutism A persistent failure to speak in certain social situations (i.e., school) where speaking is expected, despite speaking in other situations. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology C26739 Sensorineural Deafness Sensorineural Hearing Loss Hearing loss caused by a problem in the inner ear or auditory nerve. A sensorineural loss often affects a person's ability to hear some frequencies more than others. This means that sounds may be appear distorted, even with the use of a hearing aid. Sensorineural losses can range from mild to profound. C35731 Hearing Loss C97150 NICHD Neurological Development Terminology C63711 Neurosensory Disorder Sensory Disorder An interruption or alteration in the sensory activity or functions of the nervous system. C2991 Disease or Disorder C97150 NICHD Neurological Development Terminology C35014 Separation Anxiety Disorder Separation Anxiety Disorder An anxiety disorder characterized by recurrent excessive distress due to fear of separation from the home or from major attachment figures; the distress is developmentally inappropriate and causes impairment in social, academic, or other areas of functioning. C92190 Childhood Mental Disorder C97150 NICHD Neurological Development Terminology C34927 Social Phobia Social Anxiety Disorder An anxiety disorder characterized by an intense, irrational fear of one or more social or performance situations in which the individual believes that he or she will be scrutinized by others. Exposure to social situations immediately provokes an anxiety response. In adults, the social phobia is recognized as excessive or unreasonable. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology C35284 Specific Phobia Specific Phobia An anxiety disorder characterized by an intense, irrational fear cued by the presence or anticipation of a specific object or situation. Exposure to the phobic stimulus immediately provokes an anxiety response. In adults, the specific phobia is recognized as excessive or unreasonable. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology C5041 Speech Manifestations Speech Disorder A term referring to disorders characterized by the disruption of normal speech. It includes stuttering, lisps, dysarthria and voice disorders. C9229 Systemic Disorder C97150 NICHD Neurological Development Terminology C35078 Tourette Syndrome Tourette's Syndrome A neurologic disorder caused by defective metabolism of the neurotransmitters in the brain. It is characterized by repeated involuntary movements (motor tics) and uncontrollable vocal sounds (vocal tics). The symptoms are usually manifested before the age of eighteen. C96412 Brain Development Abnormality C97150 NICHD Neurological Development Terminology C35126 Vision Disorder Vision Disorder Visual impairments limiting one or more of the basic functions of the eye: visual acuity, dark adaptation, color vision, or peripheral vision. These may result from eye diseases, optic nerve diseases, visual pathway diseases, occipital lobe diseases, ocular motility disorders' and other conditions. C63711 Sensory Disorder C97150 NICHD Neurological Development Terminology C35275 Visual Cortex Disorder Visual Cortex Disorder Cortical Visual Impairment A vision disorder that results from damage of the part of the cerebral cortex that is involved in the processing of visual information. C35126 Vision Disorder C97150 NICHD Neurological Development Terminology C12664 Abdominal Cavity Abdomen The portion of the body that lies between the thorax and the pelvis. C32221 Body Part C89506 NICHD Newborn Screening Terminology C25407 Address Address A standardized representation of the location of a person, business, building, or organization. C16495 Demographics C89506 NICHD Newborn Screening Terminology C81229 Alcohol Use History Alcohol Use History A description of an individual's current and past experience with alcoholic beverage consumption. C18772 Personal Medical History C89506 NICHD Newborn Screening Terminology C15181 Anesthesia Procedure Anesthesia Procedure Treatment with a pharmacological substance that produces a loss of feeling. C25218 Intervention or Procedure C89506 NICHD Newborn Screening Terminology C32078 Ankle Joint Ankle Joint A gliding joint between the distal ends of the tibia and fibula and the proximal end of the talus. C32221 Body Part C89506 NICHD Newborn Screening Terminology C73437 APGAR Score APGAR Score The numerical sum between zero and ten that is computed from individual values of zero to two that are assigned to five different areas of interest in newborn screenings. These areas are breathing, muscle tone, pulse rate, reflex irritability and skin color. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C81230 APGAR Test APGAR Test A test devised by Dr. Virginia Apgar to assess the overall health of a newborn upon birth. The test is administered at one and five minutes after birth and allows for the assignation of numerical values between zero and two for specific observations regarding skin color, pulse rate, reflex irritability, muscle tone and breathing. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C32141 Arm Arm The portion of the upper extremity between the shoulder and the elbow. For clinical purposes this term is also used to refer to the whole superior limb. C32221 Body Part C89506 NICHD Newborn Screening Terminology C90496 Arm Recoil Arm Recoil Measurement A test commonly administered to assess the physiologic response to extending the arms as straight as possible alongside the body when lying down. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C81231 Attending Health Care Provider Attending Health Care Provider The individual assigned to be the primary care manager overseeing a patient's medical care during an episode of hospitalization. C25190 Person C89506 NICHD Newborn Screening Terminology C38036 Audiometric Test Audiometric Test Testing conducted utilizing a manual or microprocessor audiometer to test for hearing loss. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C2890 Bacterial Infection Bacterial Disease An acute infectious disorder caused by gram positive or gram negative bacteria. Representative examples include pneumococcal , streptococcal, salmonella and meningeal infections. C26726 Infectious Disease C89506 NICHD Newborn Screening Terminology C81282 Dubowitz Score Ballard/Dubowitz Score The numerical value that represents a clinical assessment of neurological and physical criteria, performed between birth and five days of age, to determine an infant's gestational age and maturity. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C89512 Barlow's Maneuver Barlow's Maneuver Useful in assessing for developmental dysplasia of the hip, this test is performed when the thigh is pushed posteriorly and the hip is adducted. Should the hip become dislocated by this movement, the result is considered positive. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C61454 Basilar Rales Basilar Rales Abnormal breath sounds (crackles) heard on auscultation only in the bases of the lungs. They indicate inflammation, fluid, or infection in the air sacs of the lung. C4876 Symptom C89506 NICHD Newborn Screening Terminology C81232 Bayley Scale of Infant Development Bayley Scales of Infant Development A standardized series of measurements that assesses the cognitive, motor, and behavioral development in infants and babies from one to twenty-four months of age. C81314 Newborn Behavioral Examination C89506 NICHD Newborn Screening Terminology C81234 Behavioral Assessment Behavioral Assessment Assessment of individual responses to age appropriate stimuli. C25214 Evaluation Procedure C89506 NICHD Newborn Screening Terminology C81233 Behavioral Development Behavioral Development The evolution of actions, including reactions and responses to the environment, over an individual's lifespan. C17770 Maturation C89506 NICHD Newborn Screening Terminology C81235 Behavioral Rating Scale Behavioral Rating Scale A range of values designed to quantify the qualitative responses of an individual to a set of challenges. C81314 Newborn Behavioral Examination C89506 NICHD Newborn Screening Terminology C81236 Birth Complication Birth Complication The development of a problematic medical situation that occurs concurrently with the birth of a neonate. C92718 Finding during Childbirth Labor C89506 NICHD Newborn Screening Terminology C68615 Birth Date Birth Date The calendar date on which a person was born. C25164 Date C89506 NICHD Newborn Screening Terminology C81237 Birth Facility Birth Facility The facility which provides a setting with provisions for monitoring and delivering babies. C16495 Demographics C89506 NICHD Newborn Screening Terminology C81296 Birth Time Birth Time The hour, minute, and/or second at which birth occurs. C25207 Time C89506 NICHD Newborn Screening Terminology C76325 Birth Weight Birth Weight In humans, the weight of a neonate measured within one hour after birth. The factors influencing the birth weight include but not limited to infant sex, racial and ethnic group, maternal size and health status, concurrent diseases, parity, and nutrition, pregnancy environment and conditions, e.g. altitude of geographic area. C81328 Body Weight C89506 NICHD Newborn Screening Terminology C54706 Blood Pressure Blood Pressure The pressure of the circulating blood against the walls of the blood vessels. C25447 Characteristic C89506 NICHD Newborn Screening Terminology C81304 Blood Product Blood Product Any natural or synthetic composition that replicates the structure or function of a native component of blood. C45306 Substance C89506 NICHD Newborn Screening Terminology C15192 Blood Transfusion Blood Transfusion The injection of whole blood or a blood component directly into the bloodstream. C49236 Therapeutic Procedure C89506 NICHD Newborn Screening Terminology C32221 Body Part Body Part Any part of an organism. C12219 Anatomic Structure or System C89506 NICHD Newborn Screening Terminology C81328 Body Weight Body Weight The weight of a subject. C25447 Characteristic C89506 NICHD Newborn Screening Terminology C81305 Bottle Feeding Bottle Feeding Provision of liquid nutrition via a closed container system with a rubber like mouthpiece resembling a nipple. C81267 Feeding Method C89506 NICHD Newborn Screening Terminology C81238 Brazelton Neonatal Behavioral Assessment Scale Brazelton Neonatal Behavioral Assessment Scale An assessment tool created by Dr. T. Berry Brazelton and his colleagues to assist caregivers in determining developmental strengths and weaknesses in infants from birth to the age of two months. C81314 Newborn Behavioral Examination C89506 NICHD Newborn Screening Terminology C25596 Breast Feeding Breast Feeding The nursing of an infant at the mother's breast. C19988 Organismal Process C89506 NICHD Newborn Screening Terminology C13257 Breast Milk Breast Milk Milk produced by female mammals for the purpose of feeding their young. C13236 Biological Substance C89506 NICHD Newborn Screening Terminology C81306 Breathing Effort Score Breathing Effort Score A component of the APGAR score, it is the numerical value assigned to the assessment of breathing effort by a neonate. 0 = no spontaneous respirations; 1 = slow or irregular respirations or a weak cry; 2 = strong, consistent respirations with a robust cry. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C46088 Caesarian Section Caesarian Section C-Section The delivery of an infant through a surgical abdominal incision. Surgery is performed when there may be complications associated with a vaginal birth and increased risk to the mother or fetus. C81179 Delivery Procedure C89506 NICHD Newborn Screening Terminology C87067 Caput Succedaneum Caput Succedaneum A diffuse swelling of the scalp in a newborn, usually caused by the trauma of the scalp pushing through a narrowed cervix during birth. The swelling may extend across the midline of the scalp and may exhibit discoloration or bruising. C81236 Birth Complication C89506 NICHD Newborn Screening Terminology C2931 Cardiovascular Disorder Cardiovascular Disorder A non-neoplastic or neoplastic disorder affecting the heart or the vessels (arteries, veins and lymph vessels). Representative examples of non-neoplastic cardiovascular disorders are endocarditis and hypertension. Representative examples of neoplastic cardiovascular disorders are endocardial myxoma and angiosarcoma. C2991 Disease or Disorder C89506 NICHD Newborn Screening Terminology C81239 Cause of Death Cause of Death The circumstance or condition that results in the death of a living being. C70856 Observational Result C89506 NICHD Newborn Screening Terminology C81240 Cellular Telephone Number Cellular Telephone Number The sequence of numbers or characters, that when dialed, connects to a particular cellular telephone. C40978 Telephone Number C89506 NICHD Newborn Screening Terminology C49668 Centimeter Centimeter A basic unit of length in the former CGS version of metric system, equal to one hundredth of a meter or approximately 0.393 700 787 inch. C25709 Unit of Measure C89506 NICHD Newborn Screening Terminology C87124 Central Nervous System Signs and Symptoms Central Nervous System Signs and Symptoms Signs and symptoms associated with disturbances within the central nervous system, which includes the brain, spinal cord and meninges. C4876 Symptom C89506 NICHD Newborn Screening Terminology C50484 Fetal Cephalhematoma Cephalhematoma A subperiosteal hemorrhage limited to the surface of one cranial bone, a usually benign condition seen in the newborn as a result of bone trauma. C81236 Birth Complication C89506 NICHD Newborn Screening Terminology C25447 Characteristic Characteristic The distinguishing qualities or prominent aspect of a person, object, action, process, or substance. C20189 Property or Attribute C89506 NICHD Newborn Screening Terminology C87068 Circumcision Circumcision Surgical removal of the prepuce (foreskin) of a male; the foreskin is the fold of skin covering the glans of the penis. C15329 Surgical Procedure C89506 NICHD Newborn Screening Terminology C25160 City City A large and densely populated urban area; a city specified in an address. C16495 Demographics C89506 NICHD Newborn Screening Terminology C87175 Cleft Lip Cleft Lip A congenital abnormality consisting of one or more clefts (splits) in the upper lip, which may be accompanied by a cleft palate; it is the result of the failure of the embryonic parts of the lip to fuse. C97171 Congenital Abnormality of the Digestive System C89506 NICHD Newborn Screening Terminology C87069 Cleft Palate Cleft Palate A congenital abnormality consisting of a fissure in the midline of the hard and/or soft palate; it is the result of the failure of the two sides of the palate to fuse during embryonic development. C97171 Congenital Abnormality of the Digestive System C89506 NICHD Newborn Screening Terminology C77140 Clinical Test Result Clinical Test Result The result of a laboratory, radiologic, or other clinical test performed to determine the presence, absence, or degree of a condition. C70856 Observational Result C89506 NICHD Newborn Screening Terminology C34484 Clonus Clonus A form of involuntary muscular movement characterized by alternating contractions and relaxation in rapid succession. In the context of reflex testing, the ability to elicit clonus indicates injury to the nerve tracts above the point at which the reflex was initiated. C4876 Symptom C89506 NICHD Newborn Screening Terminology C34491 Clubbing of Fingers Clubbing of Fingers An abnormal enlargement of the terminal phalanges accompanied by increased length-wise curvature of the nails, giving the digits a club-like appearance. Clubbing has been noted with a wide variety of conditions, including pulmonary and cardiac diseases, liver disorders, and disorders of the gastrointestinal tract. C89337 Congenital Abnormality of the Musculoskeletal System C89506 NICHD Newborn Screening Terminology C84641 Clubfoot Clubfoot The most common congenital deformation of the foot, occurring in 1 of 1,000 live births. The most common form is talipes equinovarus, where the deformed foot is turned downward and inward sharply. C89337 Congenital Abnormality of the Musculoskeletal System C89506 NICHD Newborn Screening Terminology C62736 Cognitive Assessment Cognitive Assessment The examination of the cognitive capacities or deficits of an individual through the application of tests that probe that individual's ability to perform various mental activities such as perception, learning, and reasoning. C81313 Neurologic Examination C89506 NICHD Newborn Screening Terminology C81241 Cognitive Development Cognitive Development The evolution of an individual's problem solving skills, memory, language development, and ability to process information about their environment. C17770 Maturation C89506 NICHD Newborn Screening Terminology C81286 Collection Date Collection Date The date on which the sample or data was collected. C25164 Date C89506 NICHD Newborn Screening Terminology C81287 Collection Time Collection Time The hour, minute, and/or second at which the sample or data was collected. C25207 Time C89506 NICHD Newborn Screening Terminology C2849 Congenital Abnormality Congenital Abnormality Any abnormality, anatomical or biochemical, evident at birth or during the neonatal period. C89328 Pediatric Disease or Disorder C89506 NICHD Newborn Screening Terminology C89337 Congenital Musculoskeletal Defect Congenital Abnormality of the Musculoskeletal System An abnormality of the musculoskeletal system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C89506 NICHD Newborn Screening Terminology C26734 Congenital Hypothyroidism Congenital Hypothyroidism A deficiency of thyroid hormone present at birth. The etiology can be genetic or environmental, or a combination of both; treatment is based on severity and causality. C34816 Congenital Metabolic Disorder C89506 NICHD Newborn Screening Terminology C34816 Congenital Metabolic Disorder Congenital Metabolic Disorder A group of disorders present at birth that involve genetic defects leading to disturbances in carbohydrate, lipid, lysosomal storage or amino acid metabolism in the body. C97151 Systemic Congenital Disorder C89506 NICHD Newborn Screening Terminology C390 Contrast Agent Contrast Agent Substances administered during diagnostic procedures that allows delineation of internal structures. Contrast agents appear opaque due to the difference in absorption of X-rays or other electromagnetic waves and surrounding tissue. C45306 Substance C89506 NICHD Newborn Screening Terminology C81242 Crown to Rump Length Measurement Crown to Rump Length Measurement A measurement from the high prominence of the head to the low prominence of the buttocks of a fetus or embryo during ultrasound. This measurement is useful in determining gestational age. C81253 Gestational Weeks Assessment C89506 NICHD Newborn Screening Terminology C26737 Cyanosis Cyanosis A bluish or purplish discoloration of the skin and mucous membranes resulting from a reduced amount of oxygenated hemoglobin in the blood. C4876 Symptom C89506 NICHD Newborn Screening Terminology C87065 Cyanotic Body Cyanotic Body Blue- or purplish-colored body; this is caused by excessive amounts of deoxygenated hemoglobin in the skin vessels of the body. C4876 Symptom C89506 NICHD Newborn Screening Terminology C87066 Cyanotic Limbs Cyanotic Limbs Blue- or purplish-colored limbs; this is caused by excessive amounts of deoxygenated hemoglobin in the skin vessels of the limbs. C4876 Symptom C89506 NICHD Newborn Screening Terminology C3724 Cystic Hygroma Cystic Hygroma Cystic Lymphangioma A benign lymphatic neoplasm usually arising from the neck and characterized by cystic dilation of the lymphatic vessels. C2978 Cyst C89506 NICHD Newborn Screening Terminology C49100 Data Value Data Value The information contained in a data field. It may represent a numeric quantity, a textual characterization, a date or time measurement, or some other state, depending on the nature of the attribute. C20189 Property or Attribute C89506 NICHD Newborn Screening Terminology C25164 Date Date The particular day, month and year an event has happened or will happen. C21514 Temporal Qualifier C89506 NICHD Newborn Screening Terminology C27644 Deafness Deafness An inherited or acquired condition characterized by a partial or complete loss of hearing in one or both ears. The level of impairment varies from a mild but important loss of sensitivity to a total loss of hearing. C35731 Hearing Loss C89506 NICHD Newborn Screening Terminology C81244 Deceased Sibling Deceased Sibling The historical fact that a legal or consanguineous brother or sister has died. C90491 Pregnancy Outcome C89506 NICHD Newborn Screening Terminology C81179 Birth Method of Delivery Delivery Procedure Description of the method by which a fetus is delivered. C89340 Obstetric Procedure C89506 NICHD Newborn Screening Terminology C16495 Demographics Demographics The statistical characterization of human populations or segments of human populations (e.g., characterization by age, sex, race, or income). C20189 Property or Attribute C89506 NICHD Newborn Screening Terminology C81245 Denver Development Screening Test Denver Development Screening Test A test developed at the University of Colorado Medical Center to assess the developmental status of infants and children from birth to six years of age. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C9011 Dermoid Cyst Dermoid Cyst A mature teratoma characterized by the presence of a cyst which is lined by mature tissue resembling the epidermis and the epidermal appendages. It occurs in the ovary, testis, and extragonadal sites including central nervous system and skin. C2978 Cyst C89506 NICHD Newborn Screening Terminology C84669 Dextrocardia Dextrocardia A rare congenital abnormality in which the heart is located in the right side of the chest. It is associated with other congenital heart defects. C35729 Congenital Abnormality of the Circulatory System C89506 NICHD Newborn Screening Terminology C15220 Diagnosis Diagnosis The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation. C70856 Observational Result C89506 NICHD Newborn Screening Terminology C34687 Diaphragmatic Hernia Diaphragmatic Hernia A congenital or acquired weakness or opening in the diaphragm which allows abdominal contents to protrude into the chest cavity; congenital diaphragmatic hernias are caused when the embryonic diaphragm fails to fuse. C89337 Congenital Abnormality of the Musculoskeletal System C89506 NICHD Newborn Screening Terminology C81273 Doctor's Information Doctor's Information A collection of information about a patient's doctor. C18772 Personal Medical History C89506 NICHD Newborn Screening Terminology C81246 Drug Use History Drug Use History A description of an individual's current and past use and/or abuse of drugs and chemicals. This includes prescription medication, illicit drugs and recreational substances. C18772 Personal Medical History C89506 NICHD Newborn Screening Terminology C12394 Ear Ear A sense organ needed for the detection of sound and for establishing balance. The outer ear consists of the auricle, the ear canal as well as the tympanic membrane. The middle ear is made up of an air-filled cavity behind the tympanic membrane that contains the ossicles (malleus, incus and stapes). The inner ear is made up of the cochlea needed for hearing and the vestibular apparatus required for balance. C32221 Body Part C89506 NICHD Newborn Screening Terminology C87071 Ear Dimple Ear Dimple A pit or dimple in front of the ear of a newborn is a common finding; rarely, such a dimple may get infected, which will be manifested with redness and swelling and will require medical attention. C97174 Congenital Abnormality of the Skin C89506 NICHD Newborn Screening Terminology C87167 Eclampsia Eclampsia A potentially life-threatening disorder in pregnant or puerperal women manifested by convulsions in association with hypertension, edema, and/or proteinuria. C27020 Female Reproductive System Disorder C89506 NICHD Newborn Screening Terminology C17953 Education Level Education Level An indication of the years of schooling completed in graded public, private, or parochial schools, and in colleges, universities, or professional schools. C16495 Demographics C89506 NICHD Newborn Screening Terminology C32497 Elbow Joint Elbow Joint A type of hinge joint located between the forearm and upper arm. C32221 Body Part C89506 NICHD Newborn Screening Terminology C81326 Elevated Test Result Elevated Test Result A result of a test that is higher than a previous value or a normal range of values. C77140 Clinical Test Result C89506 NICHD Newborn Screening Terminology C34144 Embryologic Structure or System Embryonic Structure or System Body tissue, region, surface, cavity, fluid, organ, or collection of organs present in, or associated with, an embryo. C12219 Anatomic Structure or System C89506 NICHD Newborn Screening Terminology C84687 Encephalocele Encephalocele A congenital neural tube closure defect resulting in the protrusion of the brain through a skull opening. When the protrusion includes the meninges, the term encephalomeningocele is used. C84923 Neural Tube Defect C89506 NICHD Newborn Screening Terminology C15642 Epidural Block Epidural Block An anesthetic procedure that involves administering pharmaceutical agents into the epidural space of the spinal canal. Frequently administered agents include local anesthetics and analgesics. C64381 Regional Anesthesia Procedure C89506 NICHD Newborn Screening Terminology C87072 Esophageal Atresia Esophageal Atresia A congenital abnormality of the esophagus in which the upper esophagus ends as a blind pouch and does not connect with the lower esophagus; it is often accompanied by a tracheoesophageal fistula. Signs and symptoms in a newborn with this abnormality include excessive salivation, choking, coughing, and the development of cyanosis and respiratory distress when fed. C97171 Congenital Abnormality of the Digestive System C89506 NICHD Newborn Screening Terminology C16564 Ethnic Group Ethnic Group A social group characterized by a distinctive social and cultural tradition that is maintained from generation to generation. Members share a common history and origin and a sense of identification with the group. They have similar and distinctive features in their lifestyle habits and shared experiences. They often have a common genetic heritage which may be reflected in their experience of health and disease. C16495 Demographics C89506 NICHD Newborn Screening Terminology C87073 Excessive Sucking Excessive Sucking A symptom of gastrointestinal dysfunction seen in neonates who have been exposed to drugs during pregnancy; often accompanied by excessive sucking of fists, fingers and thumbs. C4876 Symptom C89506 NICHD Newborn Screening Terminology C34599 Excoriation Excoriation A superficial traumatic injury to the skin caused most often by scratching, but also by abrasions or by a chemical or thermal burn. C4876 Symptom C89506 NICHD Newborn Screening Terminology C81247 Expected Date of Confinement Expected Date of Confinement The projected date of delivery for a pregnant female. C25164 Date C89506 NICHD Newborn Screening Terminology C12401 Eye Eye The organ of sight or vision. C32221 Body Part C89506 NICHD Newborn Screening Terminology C87074 Ophthalmic Prophylaxis Eye prophylaxis The practice of placing antibiotic eye drops or ointment in a neonate's eyes after birth. C49236 Therapeutic Procedure C89506 NICHD Newborn Screening Terminology C81267 Feeding Method Feeding Method A description of the technique for the manner in which a subject is administered food. C16847 Technique C89506 NICHD Newborn Screening Terminology C16576 Female Female A person who belongs to the sex that normally produces ova. The term is used to indicate biological sex distinctions, or cultural gender role distinctions, or both. C28421 Sex C89506 NICHD Newborn Screening Terminology C13235 Fetus Fetus An unborn or unhatched vertebrate in the later stages of development showing the main recognizable features of the mature being. C13229 Embryonic Structure C89506 NICHD Newborn Screening Terminology C3367 Finding Finding Objective evidence of disease perceptible to the examining practitioner (sign) and subjective evidence of disease perceived by the patient (symptom). C90259 NICHD Pediatric Terminology C89506 NICHD Newborn Screening Terminology C89343 Finnegan Score Measurement Finnegan Score Measurement A tool to evaluate neonatal abstinence syndrome (NAS), that measures the degree to which a neonate is experiencing symptoms of withdrawal due to maternal substance abuse. C89515 Neonatal Abstinence Syndrome Assessment C89506 NICHD Newborn Screening Terminology C81272 First Feeding First Feeding The first time that a neonate is provided nutrition. C25207 Time C89506 NICHD Newborn Screening Terminology C81228 Five Minutes After Birth Five Minutes After Birth The actual time that is five minutes after the birth of a fetus. This period is most commonly referenced during the administration of the APGAR test. C25207 Time C89506 NICHD Newborn Screening Terminology C32621 Fontanelle Fontanelle The four gaps in the skull of a neonate or fetus where the sutures converge. The bulging or depression of the membranous soft spots can be indicative of intracranial fluid buildup or systemic dehydration. C13229 Embryonic Structure C89506 NICHD Newborn Screening Terminology C32622 Foot Foot The structure found below the ankle joint required for locomotion. C32221 Body Part C89506 NICHD Newborn Screening Terminology C81248 Forceps Delivery Forceps Delivery The method referring to the delivery of a fetus through the vaginal canal with assistance of obstetrical forceps. C81301 Vaginal Assisted Delivery C89506 NICHD Newborn Screening Terminology C87076 Frenulum Frenulum A small fold of tissue that limits the movements of an organ or body part; for example, the lingual frenulum connects the tongue to the floor of the mouth and restrains its movement. C32221 Body Part C89506 NICHD Newborn Screening Terminology C89333 Full Term Neonate Full Term Neonate An infant born after completion of the normal gestational period. C16731 Newborn C89506 NICHD Newborn Screening Terminology C87077 Fused Eyelid Fused Eyelid A congenital abnormality in which the margins of the upper and lower eyelids are fused together by bands of tissue. C97174 Congenital Abnormality of the Skin C89506 NICHD Newborn Screening Terminology C81308 Galactose Measurement Galactose Measurement The measurement of the amount of galactose in a biologic specimen. C25294 Laboratory Procedure C89506 NICHD Newborn Screening Terminology C81251 Galactose-1-Phosphate Uridyltransferase Measurement Galactose-1-Phosphate Uridyltransferase Measurement The measurement of the galactose-1-phosphate uridyltransferase in a biologic specimen. C25294 Laboratory Procedure C89506 NICHD Newborn Screening Terminology C90497 Galeazzi Test Galeazzi Test An assessment for developmental dysplasia of the hip or a leg-length discrepancy, the patient is placed in a supine position and the ankles are brought to the buttocks with the hips and knees flexed. The result is considered positive when the knees are at different heights. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C3368 Gastrointestinal System Signs and Symptoms Gastrointestinal System Signs and Symptoms Signs and symptoms associated with disturbances within the gastrointestinal system, which includes the stomach, intestines and all associated organs that aid in digestion. C4876 Symptom C89506 NICHD Newborn Screening Terminology C64380 General Anesthesia Procedure General Anesthesia Procedure Actions that render a patient unconscious for the purpose of performing a diagnostic or interventional procedure. C15181 Anesthesia Procedure C89506 NICHD Newborn Screening Terminology C87079 General Appearance General Appearance The result of observation and overall assessment of a subject's outward aspect including appearance and movements; for example, in a human newborn general appearance includes skin color and tone, range of motion, and spontaneous movements. C25447 Characteristic C89506 NICHD Newborn Screening Terminology C27993 General Qualifier General Qualifier A term that helps define and render another concept unique. C20189 Property or Attribute C89506 NICHD Newborn Screening Terminology C15709 Genetic Testing Genetic Testing The process of isolating and testing the DNA of an embryo or a person to detect the presence of genetic alterations or defects that may predispose to the future development of a disease or disorder. C25294 Laboratory Procedure C89506 NICHD Newborn Screening Terminology C25177 Genitalia Genitalia The external sex organs. C32221 Body Part C89506 NICHD Newborn Screening Terminology C81252 Gesell Developmental Schedule Gesell Developmental Schedule A scale used as an instrument to assess a child's motor and language development, as well as personal-social and adaptive behaviors. C81314 Newborn Behavioral Examination C89506 NICHD Newborn Screening Terminology C81253 Gestational Weeks Assessment Gestational Weeks Assessment A standard determination of fetal age; it is the number of weeks since the first day of the last menstrual period of the mother to the date of interest. C90341 Pediatric Intervention or Procedure C89506 NICHD Newborn Screening Terminology C26785 Goiter Goiter Enlargement of the thyroid gland usually caused by lack of iodine in the diet, hyperthyroidism, or thyroid nodules. Symptoms include difficulty in breathing and swallowing. C3009 Endocrine System Disorder C26836 Nutritional Disorder C89506 NICHD Newborn Screening Terminology C48155 Gram Gram The metric unit of mass equal to one thousandth of a kilogram. One gram equals approximately 15.432 grains or 0.035 273 966 ounce. C25709 Unit of Measure C89506 NICHD Newborn Screening Terminology C81254 Grasp Reflex Grasp Reflex An involuntary, primal response in the neonate to grasp the fingers when their palm is touched. This reflex is present until six months of age. C81181 Infant Reflex C89506 NICHD Newborn Screening Terminology C87168 Group B Streptococcal Infection Group B Streptococcal Infection Group B Streptococcus, also known as Streptococcus agalactiae, colonizes the vaginal and gastrointestinal tracts of up to 45% of healthy women and may infect neonates in utero or during delivery, causing neonatal sepsis in 1-2% of colonized neonates. GBS infection may also occur in nonpregnant (particularly elderly) adults with underlying medical conditions, presenting as urinary tract infection, pneumonia, or soft-tissue infection. C2890 Bacterial Disease C89506 NICHD Newborn Screening Terminology C32712 Hand Hand The distal portion of the upper extremity. It consists of the carpus, metacarpus, and digits. C32221 Body Part C89506 NICHD Newborn Screening Terminology C12419 Head Head The anterior and superior part of a human bearing the mouth, the brain and sensory organs. C32221 Body Part C89506 NICHD Newborn Screening Terminology C81255 Head Circumference Head Circumference A circumferential measurement of the head at the widest point, which is traditionally above the eyebrows. C25334 Length C89506 NICHD Newborn Screening Terminology C25178 Health Health Refers to a person's state of physical, mental and social well-being; usually it refers specifically to the state of being in good health, a state of complete physical, mental and social well-being, and does not consist only of the absence of disease or infirmity. In any organism health constitutes a form of homeostasis with inputs and outputs of energy and mass in approximate equilibrium allowing for growth and continued survival. In humans, a subjective feeling of well-being coming from somatic and cognitive perceptions is considered an essential component of health. C92722 Qualitative Concept C89506 NICHD Newborn Screening Terminology C84480 Heart Murmur Heart Murmur A periodic humming or blowing sound heard on auscultation of the heart that can indicate the presence of cardiac disease; murmurs are the result of vibrations caused by the turbulent flow of blood in the heart or great vessels. Murmurs are characterized according to the area of generation (mitral, aortic, tricuspid, or pulmonary) and according to the period of the cycle (systolic or diastolic). C2931 Cardiovascular Disorder C89506 NICHD Newborn Screening Terminology C49677 Heart Rate Heart Rate The number of heartbeats per unit of time, usually expressed as beats per minute. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C81309 Heart Rate Score Heart Rate Score A component of the APGAR score, it is the numerical value assigned to an assessment of the circulatory status of a neonate. 0 = no pulse; 1 = rate less than 100 beats per minute; 2 = rate greater than 100 beats per minute. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C87081 Heart Rhythm Heart Rhythm The recurrent, measured movements (rhythm) of a beating heart. C25447 Characteristic C89506 NICHD Newborn Screening Terminology C89513 Heel to Ear Measurement Heel to Ear Measurement Useful in assessing neonatal neuromuscular development, this is obtained when the infant is placed in a supine position and the infant's feet are grasped pulled toward the ipsilateral ears. The examiner measures the angle made by the arc from the table to the infant's heels; increased angle for age suggests hypotonia, and decreased angle for age suggests hypertonia. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C84750 HELLP Syndrome HELLP Syndrome A life-threatening complication of pregnancy usually occurring in women with preeclampsia or eclampsia. It is characterized by hemolytic anemia, elevated liver enzymes, and low platelet count. Signs and symptoms include headaches, nausea, vomiting, blurred vision, and upper abdominal pain. It may lead to diffuse intravascular coagulation and acute renal failure. C85021 Preeclampsia C89506 NICHD Newborn Screening Terminology C3085 Hemangioma Hemangioma A benign localized vascular neoplasm usually occurring in infancy and childhood. It is characterized by the formation of capillary-sized or cavernous vascular channels. The majority of cases are congenital. C2978 Cyst C89506 NICHD Newborn Screening Terminology C81276 Hemoglobin A to Total Hemoglobin Ratio Measurement Hemoglobin A to Total Hemoglobin Ratio Measurement The determination of the ratio of Hemoglobin A compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage. C25294 Laboratory Procedure C89506 NICHD Newborn Screening Terminology C81277 Hemoglobin A2 to Total Hemoglobin Ratio Measurement Hemoglobin A2 to Total Hemoglobin Ratio Measurement The determination of the ratio of Hemoglobin A2 compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage. C25294 Laboratory Procedure C89506 NICHD Newborn Screening Terminology C34675 Hemoglobin C Disease Hemoglobin C Disease A blood disorder characterized by the appearance of sickle-shaped red blood cells and anemia. This disorder is caused by a specific mutation in the beta-globin HBB gene, whereby a lysine is substituted for a glutamic acid at the sixth amino acid in the protein. C35729 Congenital Abnormality of the Circulatory System C89506 NICHD Newborn Screening Terminology C81278 Hemoglobin C to Total Hemoglobin Ratio Measurement Hemoglobin C to Total Hemoglobin Ratio Measurement The determination of the ratio of Hemoglobin C compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage. C25294 Laboratory Procedure C89506 NICHD Newborn Screening Terminology C64848 Hemoglobin Measurement Hemoglobin Measurement A quantitative measurement of the amount of hemoglobin present in a sample. C25294 Laboratory Procedure C89506 NICHD Newborn Screening Terminology C81279 Hemoglobin S to Total Hemoglobin Ratio Measurement Hemoglobin S to Total Hemoglobin Ratio Measurement The determination of the ratio of Hemoglobin S compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage. C25294 Laboratory Procedure C89506 NICHD Newborn Screening Terminology C87115 Hemolytic Disease of the Newborn Hemolytic Disease of the Newborn A disorder caused when there is a Rh-factor blood-type incompatibility between the mother and fetus, and the mother's immune system forms antibodies that attack the red blood cells of her unborn child. This disorder can only occur if the mother is Rh-negative and the fetus is Rh-positive. C35729 Congenital Abnormality of the Circulatory System C89506 NICHD Newborn Screening Terminology C87083 Heterotaxia Heterotaxia The abnormal arrangement or position of thoracic and/or abdominal organs in relation to each other, often occurring in a right/left transposition. C97151 Systemic Congenital Disorder C89506 NICHD Newborn Screening Terminology C87169 High Pitched Cry High Pitched Cry A symptom in infants that could possibly indicate the presence of one of an array of medical conditions or congenital syndromes, including birth trauma, craniosynostosis, Arnold-Chiari deformity, meningitis, and cri-du-chat syndrome (deletion of the short arm of chromosome 5). C4876 Symptom C89506 NICHD Newborn Screening Terminology C70933 High Test Reference Range High Test Reference Range Reported upper limit of the test reference range. C38013 Range C89506 NICHD Newborn Screening Terminology C87084 Hyperemesis Gravidarum Hyperemesis Gravidarum Severe, intractable vomiting during pregnancy (usually the first trimester) accompanied by dehydration, weight loss, and electrolyte imbalances. C34941 Pregnancy Complication C89506 NICHD Newborn Screening Terminology C50589 Hyperthermia Hyperthermia A condition that manifests with abnormally high body temperature. In hyperthermic state, the hypothalamic set-point is normal but body temperature increases and overrides the ability to lose heat, resulting from exogenous heat exposure or endogenous heat production, e.g. in heat stroke, malignant hyperthermia, endocrine hyperthermia, or neuroleptic malignant syndrome. The concept does not refer to hyperpyrexia, the state when the hypothalamic set-point is reset at a higher temperature and is physiologically regulated. C4876 Symptom C89506 NICHD Newborn Screening Terminology C87085 Hypertonia Hypertonia A condition of increased muscle tone manifested by increased resistance of the muscle to passive stretching. C4876 Symptom C89506 NICHD Newborn Screening Terminology C87070 Hypotonia Hypotonia A condition of decreased tone of the skeletal muscles and diminished resistance to passive stretching. C4876 Symptom C89506 NICHD Newborn Screening Terminology C3890 Hypoxia Hypoxia A decrease in the amount of oxygen in the body. Symptoms range from mild (impaired judgment, memory loss, impaired motor coordination) to severe (seizures and coma). C81236 Birth Complication C89506 NICHD Newborn Screening Terminology C25737 Identification Identification The procedure of having an identity established. C92722 Qualitative Concept C89506 NICHD Newborn Screening Terminology C81289 Image Identifier Image Identifier A sequence of letters, numbers, or other characters that specifically identifies a particular image. C18772 Personal Medical History C89506 NICHD Newborn Screening Terminology C81256 Imaging Information Imaging Information A collection of data pertinent to a radiographic study. C18772 Personal Medical History C89506 NICHD Newborn Screening Terminology C48500 Inch Inch A traditional unit of length equal to 2.54 centimeters. C25709 Unit of Measure C89506 NICHD Newborn Screening Terminology C25180 Indicator Indicator An event, entity or condition that typically characterizes a prescribed environment or situation and determines or aids in determining whether certain stated circumstances exist or criteria are satisfied. C92722 Qualitative Concept C89506 NICHD Newborn Screening Terminology C81249 Infant Formula Infant Formula A nutritional substitute for breast milk, usually with a foundation of cow or soy milk. C45306 Substance C89506 NICHD Newborn Screening Terminology C81181 Infant Reflex Infant Reflex Primitive reflex actions that newborns display in response to specific stimuli. These reflexes are involuntary and most disappear as the infant matures. C90346 Child Behavior C89506 NICHD Newborn Screening Terminology C89514 Palmar Crease Examination Inspection of palm crease When examining the infant's palm for abnormalities, the examiner may note a single transverse palmar crease, which is found in 5% of newborns and is frequently inherited as a familial trait. However, single palmar creases can be associated with Down's syndrome and other genetic disorders, or with fetal alcohol syndrome. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C87087 Intercostal Retractions Intercostal Retractions The marked inward movement of the muscles between the ribs during inhalation; they indicate that there is reduced pressure in the chest cavity and can be a sign of breathing difficulties. C4876 Symptom C89506 NICHD Newborn Screening Terminology C32856 Internal Nare Internal Nare The inner portion of the nostrils of the nose. C32221 Body Part C89506 NICHD Newborn Screening Terminology C87089 Irregular Respiration Irregular Breathing A change from the normal breathing pattern in an infant, child, or adult, in terms of the amplitude and frequency of inhalations and exhalations. C4876 Symptom C89506 NICHD Newborn Screening Terminology C32884 Ischium Ischium The most posterior and ventral bone making up the pelvis. C32221 Body Part C89506 NICHD Newborn Screening Terminology C25215 Karyotype Karyotype The appearance of the chromosomal makeup of a somatic cell in an individual or species, including the number and arrangement and size and structure of the chromosomes. C15709 Genetic Testing C89506 NICHD Newborn Screening Terminology C32898 Knee Joint Knee Joint A joint connecting the lower part of the femur with the upper part of the tibia. The lower part of the femur and the upper part of the tibia are attached to each other by ligaments. Other structures of the knee joint include the upper part of the fibula, located below and parallel to the tibia, and the patella which moves as the knee bends. C32221 Body Part C89506 NICHD Newborn Screening Terminology C87090 Labial Fusion Labial Fusion Usually found in girls between 6 months and 6 years of age, this condition occurs wherein the labia grow together instead of as 2 separate folds, thereby blocking the opening of the vagina. It is caused by conditions such as repeated diaper rash, urine and stool infections, and sexual abuse. The condition often spontaneously corrects or responds to the application of estrogen cream. C35107 Congenital Abnormality of the Genitourinary System C89506 NICHD Newborn Screening Terminology C25294 Laboratory Procedure Laboratory Procedure Any procedure that involves testing or manipulating a sample of blood, urine, or other body substance in a laboratory setting. C25218 Intervention or Procedure C89506 NICHD Newborn Screening Terminology C36292 Laboratory Test Result Laboratory Test Result The outcome of a laboratory test. C77140 Clinical Test Result C89506 NICHD Newborn Screening Terminology C34197 Lanugo Lanugo Fine downy hair that covers the body of a human fetus beginning in the fifth month of gestation; it is usually shed by the ninth month of gestation. C13229 Embryonic Structure C89506 NICHD Newborn Screening Terminology C87092 Large for Gestational Age Large for Gestational Age A fetus or infant who is larger than expected for the age or gender, or who has a birthweight greater than the 90th percentile. C25447 Characteristic C89506 NICHD Newborn Screening Terminology C81310 Lasso-O Measuring Tape Lasso-O Measuring Tape A measuring tape frequently used to measure head circumference in newborns. C81261 Measuring Tape C89506 NICHD Newborn Screening Terminology C81257 Last Menstrual Period Last Menstrual Period The first day of the female's last menstrual cycle. C92720 Pregnancy Finding C89506 NICHD Newborn Screening Terminology C81258 Last Screening Last Screening The most recent screening. C25164 Date C89506 NICHD Newborn Screening Terminology C81259 Left Ear Left Ear The organ of hearing located on the left side of the head. C32221 Body Part C89506 NICHD Newborn Screening Terminology C32974 Leg Leg One of the two lower extremities in humans used for locomotion and support. C32221 Body Part C89506 NICHD Newborn Screening Terminology C25334 Length Length The linear extent in space from one end of something to the other end, or the extent of something from beginning to end. C25447 Characteristic C89506 NICHD Newborn Screening Terminology C12220 Lip Lip Fleshy fold which surrounds the opening of the mouth. C32221 Body Part C89506 NICHD Newborn Screening Terminology C81260 Local Anesthesia Procedure Local Anesthesia Procedure The temporary suppression of sensation at a specific region of the body by pharmacological intervention. This type of anesthesia does not induce unconsciousness in the patient. C15181 Anesthesia Procedure C89506 NICHD Newborn Screening Terminology C34724 Low Birth Weight Low Birth Weight Refers to a fetus or infant who is smaller than expected for the age or gender, or who has a birthweight less than the 10th percentile. C76325 Birth Weight C89506 NICHD Newborn Screening Terminology C70934 Low Test Reference Range Low Test Reference Range Reported low limit of the test reference range. C38013 Range C89506 NICHD Newborn Screening Terminology C50644 Lung Overinflation Lung Overinflation Abnormal permanent enlargement of the lung air spaces distal to terminal bronchiole not resulted from wall destruction, e.g. due to loss of opposite lung. C4876 Symptom C89506 NICHD Newborn Screening Terminology C25381 Maiden Name Maiden Name A woman's surname before marriage. C90492 Personal Information C89506 NICHD Newborn Screening Terminology C20197 Male Male A person who belongs to the sex that normally produces sperm. The term is used to indicate biological sex distinctions, cultural gender role distinctions, or both. C28421 Sex C89506 NICHD Newborn Screening Terminology C17770 Maturation Maturation The act, or process, of natural progression in physical and psychological maturation from a previous, lower, or embryonic stage to a later, more complex, or adult stage. C19988 Organismal Process C89506 NICHD Newborn Screening Terminology C81261 Measuring Tape Measuring Tape A pliable length of fabric, plastic, paper or some composite that is has incremental lengths imprinted on the surface. C81182 Measurement Device C89506 NICHD Newborn Screening Terminology C87093 Meconium Aspiration Syndrome Meconium Aspiration Syndrome A serious condition in which a newborn breathes a mixture of meconium (the first intestinal discharge) and amniotic fluid into the lungs around the time of delivery. Meconium aspiration syndrome occurs in 5-10 percent of births and typically occurs when the infant is stressed, as when the infant is past its due date. C97173 Congenital Abnormality of the Respiratory System C89506 NICHD Newborn Screening Terminology C81262 Medical Record Number Medical Record Number An identifying number within an institution that is used to reference a subject's medical information. C18772 Personal Medical History C89506 NICHD Newborn Screening Terminology C90603 Medication Administered at Birth Medication Given at Birth Pharmacologic agents administered to a neonate at birth. C49236 Therapeutic Procedure C89506 NICHD Newborn Screening Terminology C81263 Mental Development Index Mental Development Index A sequential arrangement of information pertaining to the evolution of an individual's cognitive development. C81314 Newborn Behavioral Examination C89506 NICHD Newborn Screening Terminology C81264 Mental Scale Mental Scale A range of values that characterizes an individual's mental development. C81314 Newborn Behavioral Examination C89506 NICHD Newborn Screening Terminology C87094 Micrognathism Micrognathism A congenital abnormality of the jaws (particularly the mandible) in which they are unusually small. This condition is not always pathological and may correct itself as the patient matures; however, it may also present as a birth defect in multiple syndromes. C89337 Congenital Abnormality of the Musculoskeletal System C89506 NICHD Newborn Screening Terminology C67405 Microinternational Unit per Milliliter Microinternational Unit per Milliliter Unit of arbitrary substance concentration (biologic activity concentration) defined as the concentration of one millionth of international unit per one milliliter of system volume. C25709 Unit of Measure C89506 NICHD Newborn Screening Terminology C67015 Milligram per Deciliter Milligram per Deciliter A unit of mass concentration defined as the concentration of one milligram of a substance in unit volume of the mixture equal to one cubic deciliter or 100 cubic centimeters. It is also a unit of mass density (volumic mass) defined as the density of substance which mass equal to one milligram occupies the volume one cubic deciliter or 100 cubic centimeters. C25709 Unit of Measure C89506 NICHD Newborn Screening Terminology C64387 Millimole per Liter Millimole per Liter A unit of concentration (molarity unit) equal to one thousandth of a mole (10E-3 mole) of solute per one liter of solution. C25709 Unit of Measure C89506 NICHD Newborn Screening Terminology C41147 Modality Modality A specific manner, characteristic, pattern of application or the employment of, any therapeutic agent or method of treatment, especially involving the physical treatment of a condition. C25447 Characteristic C89506 NICHD Newborn Screening Terminology C81268 Molar Ratio Molar Ratio The relative number of moles of one substance to another in a chemical reaction. C25709 Unit of Measure C89506 NICHD Newborn Screening Terminology C81311 Moro Reflex Moro Reflex An involuntary, primal response in the neonate to loud noise or the feeling of falling. The response is characterized by the infant's arms symmetrically spreading out to the side and then back to the midline, and involuntarily flexion of the fingers and toes. C81181 Infant Reflex C89506 NICHD Newborn Screening Terminology C81269 Motor Development Motor Development The evolution of physical movement over an individual's lifespan. C17770 Maturation C89506 NICHD Newborn Screening Terminology C5039 Motor Manifestations Motor Manifestations The presence of an alteration in the ability to move one's body or any body parts in accordance with one's intent. C4876 Symptom C89506 NICHD Newborn Screening Terminology C87095 Mottling Mottling A patchy appearance of the skin caused by underlying blood vessel changes. C4876 Symptom C89506 NICHD Newborn Screening Terminology C87096 Movement of Lip Corners Movement of Lip Corners During examination of the newborn infant, the examiner looks for symmetric movement of the lip corners. Movement of the lip corners is governed by the zygomatic major muscle. C4876 Symptom C89506 NICHD Newborn Screening Terminology C81271 Multiple Birth Multiple Birth A single birthing event that produces two or more offspring. C90491 Pregnancy Outcome C89506 NICHD Newborn Screening Terminology C81312 Muscle Tone Score Muscle Tone Score A component of the APGAR score, it is the numerical value assigned to an assessment of the residual muscle tension of a neonate. 0 = flaccid; 1 = flexion of extremities; 2 = active motion. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C34832 Myoclonic Jerk Myoclonic Jerk A sudden, involuntary contraction of a muscle or group of muscles; these movements may develop as a symptom of a number of neurological diseases including epilepsy, Parkinson's disease, Alzheimer's disease, or Creutzfeldt-Jacob disease. C4876 Symptom C89506 NICHD Newborn Screening Terminology C67326 Nanogram per Deciliter Nanogram per Deciliter A unit of mass concentration defined as the concentration of one nanogram of a substance per unit volume of the mixture equal to one deciliter. The concept also refers to the unit of mass density (volumic mass) defined as the density of substance which mass equal to one nanogram occupies the volume of one deciliter. C25709 Unit of Measure C89506 NICHD Newborn Screening Terminology C78500 Nasal Congestion Nasal Congestion The blockage of the nasal passage due to mucosal edema. It is usually the result of a viral infection or an allergic reaction. C4876 Symptom C89506 NICHD Newborn Screening Terminology C87099 Nasal Flaring Nasal Flaring Enlargement of the nostrils during breathing; although there are many possible causes, it can be a sign of respiratory distress in young infants. C4876 Symptom C89506 NICHD Newborn Screening Terminology C13063 Neck Neck The region that connects the head to the rest of the body. C32221 Body Part C89506 NICHD Newborn Screening Terminology C87101 Neonatal Abstinence Syndrome Neonatal Abstinence Syndrome A constellation of signs and symptoms observable in a neonate that are consistent with maternal substance abuse or withdrawal while pregnant. C97151 Systemic Congenital Disorder C89506 NICHD Newborn Screening Terminology C89515 Neonatal Abstinence Syndrome Assessment Neonatal Abstinence Syndrome Assessment The measurement of the degree to which a neonate is experiencing symptoms of withdrawal due to maternal substance abuse; the score can be used to determine subsequent treatment of the infant. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C84923 Neural Tube Defect Neural Tube Defect A congenital defect characterized by failure of the neural tube to close completely; this results in the presence of openings in the brain or spinal cord. Examples of neural tube defects include encephalocele and spina bifida. C97172 Congenital Abnormality of the Nervous System C89506 NICHD Newborn Screening Terminology C81313 Neurologic Examination Neurologic Examination The assessment of the functionality of the brain, spinal column, and nerves. C18020 Diagnostic Procedure C89506 NICHD Newborn Screening Terminology C89339 Neurological Screening Neurological Screening A specific type of neurologic examination for early detection of disease(s) and/or disorder(s). C81313 Neurologic Examination C89506 NICHD Newborn Screening Terminology C89516 Neuromuscular Maturity Assessment Neuromuscular Maturity Assessment An examination of the following neonatal attributes: 1) posture; 2) the "square window" (how far the baby's hands can be flexed toward the wrist); 3) arm recoil; 4) "popliteal angle" (how far the baby's knees extend); 5) "scarf sign" (how far the baby's elbows can be moved across the chest); and 6) "heel to ear" (how far the baby's feet can be moved to the ears). It is a subscore of the Dubowitz/Ballard Examination for Gestational Age. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C16731 Newborn Newborn An infant during the first month after birth. C42708 Child C89506 NICHD Newborn Screening Terminology C81314 Newborn Behavioral Examination Newborn Behavioral Examination The assessment of behavior in neonates. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C87105 Newborn Blood Pressure Newborn Blood Pressure The systolic and diastolic blood pressure of the newborn upon examination; the normal range of the systolic blood pressure is 60 - 90, while the normal range of the diastolic blood pressure is 20-60. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C84749 Newborn Examination Newborn Examination A general assessment of the overall health of a newborn. C90341 Pediatric Intervention or Procedure C89506 NICHD Newborn Screening Terminology C87103 Newborn Heart Rate Newborn Heart Rate The number of heartbeats of the newborn per minute; the normal range is 100 - 180 heartbeats per minute. C49677 Heart Rate C89506 NICHD Newborn Screening Terminology C81270 Newborn Motor Scale Newborn Motor Scale A range of values used to quantify newborn motor development. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C87104 Newborn Respiratory Rate Newborn Respiratory Rate The number of inhalations and exhalations of the newborn per minute; the normal range is 30 - 60 breaths per minute. C49678 Respiratory Rate C89506 NICHD Newborn Screening Terminology C81178 Newborn Screening Newborn Screening A specific type of newborn examination performed to allow for early detection of disease(s) and/or disorder(s). C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C49487 No No The non-affirmative response to a question. C25180 Indicator C89506 NICHD Newborn Screening Terminology C78727 Normal Reference Range Normal Reference Range Reported values within the typical or expected range. C38013 Range C89506 NICHD Newborn Screening Terminology C94835 Normal Spontaneous Vaginal Delivery Normal Spontaneous Vaginal Delivery Normal Delivery A process of birthing whereby the fetus is born unaided by medical inducements or surgical intervention and without complication. C81303 Vaginal Delivery C89506 NICHD Newborn Screening Terminology C12756 Nose Nose A structure of special sense serving as an organ of the sense of smell and as an entrance to the respiratory tract. C32221 Body Part C89506 NICHD Newborn Screening Terminology C81274 Numeric Value Numeric Value Information in the form of a numeral contained in a data field. C49100 Data Value C89506 NICHD Newborn Screening Terminology C28294 Nutrition Nutrition That which is consumed to fuel necessary life processes of an organism. C19988 Organismal Process C89506 NICHD Newborn Screening Terminology C25598 Observation Observation Watching something and taking note of what happens. C18020 Diagnostic Procedure C89506 NICHD Newborn Screening Terminology C81227 One Minute After Birth One Minute After Birth The actual time that is one minute after the birth of a fetus. This period is most commonly referenced during the administration of the APGAR test. C25207 Time C89506 NICHD Newborn Screening Terminology C12421 Oral Cavity Oral Cavity The cavity located at the upper end of the alimentary canal, behind the teeth and gums that is bounded on the outside by the lips, above by the hard and soft palates and below by the tongue. C32221 Body Part C89506 NICHD Newborn Screening Terminology C89517 Ortolani Maneuver Ortolani Maneuver When testing for congenital dislocation of the hip, this is the result obtained when the examiner gently abducts the hip while pushing upward on the greater trochanter. If the hip is dislocated, it will relocate with an audible clunk, which is a positive result for this test. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C17649 Other Other Different than the one(s) previously specified or mentioned. C27993 General Qualifier C89506 NICHD Newborn Screening Terminology C48519 Ounce Ounce The traditional unit of mass. The avoirdupois ounce is equal to 1/16 pound, or 28.3495 grams, or 0.911 457 troy ounce. C25709 Unit of Measure C89506 NICHD Newborn Screening Terminology C50685 Pallor Pallor An unusual or extreme paleness, state of decreased skin coloration. C4876 Symptom C89506 NICHD Newborn Screening Terminology C81275 Pass Pass One of two possible results of a pass/fail assessment; when the result satisfies a condition. C25180 Indicator C89506 NICHD Newborn Screening Terminology C89328 Non-Neoplastic Pediatric Disorder Pediatric Disease or Disorder A non-neoplastic disease that typically manifests prior to adulthood. C2991 Disease or Disorder C89506 NICHD Newborn Screening Terminology C25190 Person Person A human being. C90259 NICHD Pediatric Terminology C89506 NICHD Newborn Screening Terminology C25191 Person Name Person Name A word or group of words indicating the identity of a person usually consisting of a first (personal) name and a last (family) name with an optional middle name. In some cultural traditions the family name comes first. C90492 Personal Information C89506 NICHD Newborn Screening Terminology C90492 Personal Information Personal Information Data, facts or figures about an individual; the set of relevant items would depend on the use case. C20189 Property or Attribute C89506 NICHD Newborn Screening Terminology C18772 Personal Medical History Personal Medical History A record of a patient's background regarding health and the occurrence of disease events of the individual. In addition, personal medical history may be a variable in epidemiologic studies. C90492 Personal Information C89506 NICHD Newborn Screening Terminology C81280 Phenylalanine Measurement Phenylalanine Measurement The measurement of the amount of phenylalanine in a biologic specimen. C25294 Laboratory Procedure C89506 NICHD Newborn Screening Terminology C81281 Phenylalanine to Tyrosine Ratio Measurement Phenylalanine to Tyrosine Ratio Measurement The determination of the ratio of phenylalanine compared to tyrosine present in a sample. The measurement may be expressed as a ratio or percentage. C25294 Laboratory Procedure C89506 NICHD Newborn Screening Terminology C81315 Phenylketonuria Phenylketonuria A disorder characterized by the body's inability to break down and utilize the essential amino acid phenylalanine. C34816 Congenital Metabolic Disorder C89506 NICHD Newborn Screening Terminology C20989 Physical Examination Physical Examination A systemic evaluation of the body and it's functions using visual inspection, palpation, percussion and auscultation. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment. C18020 Diagnostic Procedure C89506 NICHD Newborn Screening Terminology C89518 Physical Maturity Assessment Physical Maturity Assessment An examination of the following neonatal attributes: 1) skin texture; 2) lanugo; 3) plantar creases; 4) breast; 5) eyes and ears; 6) genitals, male; and 7) genitals, female. It is a subscore of the Dubowitz/Ballard Examination for Gestational Age. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C81316 Physical Symmetry Physical Symmetry A physical attribute of visual balance and proportion between opposing structures. C25447 Characteristic C89506 NICHD Newborn Screening Terminology C41148 Placement Placement Position or arrangement, as of the teeth; the state of being placed or arranged, as the assignment of a person to a appropriate clinical study. C92722 Qualitative Concept C89506 NICHD Newborn Screening Terminology C81297 Point in Time Test Given Point in Time Test Given The hour, minute, and/or second that an examination was administered. C25207 Time C89506 NICHD Newborn Screening Terminology C87110 Polydactyly Polydactyly A congenital abnormality characterized by more than 5 digits on a hand or foot. C89337 Congenital Abnormality of the Musculoskeletal System C89506 NICHD Newborn Screening Terminology C87111 Poor Feeding Poor Feeding Occurs either when an infant shows no interest in feeding or when there is an inability to take in adequate nutrition. Poor feeding is a nonspecific symptom of many disorders, including neurological, genetic, structural, metabolic, and infectious diseases. C4876 Symptom C89506 NICHD Newborn Screening Terminology C89519 Popliteal Angle Measurement Popliteal Angle Measurement An examination whereby the patient is placed supine, the hip is flexed 90 degrees, and the knee is extended until firm resistance is met. The popliteal angle is the angle from the tibia to the femur. This measurement is used to assess hamstring contracture in children with cerebral palsy. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C25621 Postal Code Postal Code Any system designed to expedite the sorting and delivery of mail by assigning a series of alphanumeric codes to each delivery area. Also used to refer to any individual delivery area code. C16495 Demographics C89506 NICHD Newborn Screening Terminology C48531 Pound Pound The traditional unit of mass. By international agreement, one avoirdupois pound is equal to exactly 0.453 592 37 kilogram, 16 ounces, or 1.215 28 troy pounds. C25709 Unit of Measure C89506 NICHD Newborn Screening Terminology C85021 Preeclampsia Preeclampsia A pregnancy-related disorder characterized by an increase in the blood pressure after the twentieth week of gestation, and by the presence of proteinuria. It may appear up to six weeks post-partum. It may lead to eclampsia with development of tonic-clonic seizures. C4371 Pregnancy Induced Hypertension C89506 NICHD Newborn Screening Terminology C34941 Pregnancy Complication Pregnancy Complication The co-occurrence of pregnancy and a disease. The disease may precede or follow conception and it may or may not have a deleterious effect on the pregnant woman or fetus. C2991 Disease or Disorder C89506 NICHD Newborn Screening Terminology C87113 Premature Rupture of Membrane Premature Rupture of Membranes PROM The condition when a patient who is beyond 37 weeks gestation presents with rupture of membranes prior to the onset of labor. Rupture of membranes is diagnosed by speculum vaginal examination of the cervix and vaginal cavity, which will show pooling of fluid in the vagina or leakage of fluid from the cervix. Preterm PROM (known as PPROM) refers to a patient who has not yet reached 37 weeks gestation and presents with rupture of membranes. C34941 Pregnancy Complication C89506 NICHD Newborn Screening Terminology C87114 Proptosis Proptosis Abnormal protrusion of one or both eyes from the socket; causes include hyperthyroidism (particularly Graves disease); bleeding behind the eye; infection, inflammation, or tumors of the orbit; and vascular disorders. C35126 Vision Disorder C89506 NICHD Newborn Screening Terminology C49676 Pulse Rate Pulse Rate The rate of the pulse as observed in an artery, expressed as beats per minute. It can be measured at several anatomical sites, including the wrist, neck, temple, groin, behind the knees, or on top of the foot. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C87108 Pupils Equal Round and Reactive to Light and Accommodation Result Pupils Equal Round and Reactive to Light and Accommodation Result While performing an assessment of the eyes, the examiner notes whether the pupils are equal and round, reactive to light, and have the ability to accommodate. If all findings are normal, the abbreviation PERRLA is noted in the examiner's account of the physical examination. C77140 Clinical Test Result C89506 NICHD Newborn Screening Terminology C87107 Pupils Equal Round and Reactive to Light Result Pupils Equal Round and Reactive to Light Result While performing an assessment of the eyes, the examiner notes whether the pupils are equal, round, and reactive to light. If all findings are normal, the abbreviation PERRL is noted in the examiner's account of the physical examination. C77140 Clinical Test Result C89506 NICHD Newborn Screening Terminology C17049 Race Race An arbitrary classification of a taxonomic group that is a division of a species. It usually arises as a consequence of geographical isolation within a species and is characterized by shared heredity, physical attributes and behavior, and in the case of humans, by common history, nationality, or geographic distribution. C16495 Demographics C89506 NICHD Newborn Screening Terminology C38013 Range Range The difference between the lowest and highest numerical values; the limits or scale of variation. C70766 Quantitative Concept C89506 NICHD Newborn Screening Terminology C12390 Rectum Rectum The terminal portion of the gastrointestinal tract, extending from the rectosigmoid junction to the anal canal. C32221 Body Part C89506 NICHD Newborn Screening Terminology C81283 Red Reflex Vision Test Red Reflex Vision Test An optic examination in which an ophthalmoscope or retinoscope is placed approximately 30cm from the eye to visualize whether a reddish hue is reflected from the retina. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C52582 Referral Referral Sending a patient from one practitioner to another for health care services. C25218 Intervention or Procedure C89506 NICHD Newborn Screening Terminology C81319 Reflex Irritability Score Reflex Irritability Score A component of the APGAR score, it is the numerical value assigned to the neonate's response to stimuli, such as a mild pinch. 0 = no reaction; 1 = grimace; 2 = grimace with a cough, sneeze, or vigorous cry. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C64381 Regional Anesthesia Procedure Regional Anesthesia Procedure The administration of pharmaceutical agents intended to produce loss of sensation in a particular anatomical region. C15181 Anesthesia Procedure C89506 NICHD Newborn Screening Terminology C50726 Regurgitation Regurgitation Flow in the opposite direction from normal, as the casting up of undigested food or gas from the stomach, or the backward flowing of blood into the heart, or between the chambers of the heart when a valve is incompetent. C4876 Symptom C89506 NICHD Newborn Screening Terminology C81284 Residential Telephone Number Residential Telephone Number The sequence of numbers or characters, that when dialed, connects to a particular residential telephone. C40978 Telephone Number C89506 NICHD Newborn Screening Terminology C49678 Respiratory Rate Respiratory Rate The rate of breathing (inhalation and exhalation) measured within in a unit time, usually expressed as breaths per minute. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C87116 Rhonchi Rhonchi An abnormal sound similar to snoring heard on auscultation of the bronchial airways, suggesting a partial obstruction due to thick secretions, a muscular spasm, or a neoplasm. C4876 Symptom C89506 NICHD Newborn Screening Terminology C81285 Right Ear Right Ear The organ of hearing located on the right side of the head. C32221 Body Part C89506 NICHD Newborn Screening Terminology C17103 Risk Factor Risk Factor Any aspect of an individual's life, behavior, an environmental exposure, or an inborn or inherited characteristic that increases the likelihood of a disease, condition or injury. C20189 Property or Attribute C89506 NICHD Newborn Screening Terminology C90498 Risk Factor Assessment Risk Factor Assessment A systematic gathering of information regarding the variables associated with an individual's increased risk of disease or infection. C25218 Intervention or Procedure C89506 NICHD Newborn Screening Terminology C81320 Rooting Reflex Rooting Reflex An involuntary, primal response in the neonate to search for the nipple when the cheek is touched. C81181 Infant Reflex C89506 NICHD Newborn Screening Terminology C87118 Sacral Dimple Sacral Dimple A sacral dimple, or pilonidal dimple, is a small hollow area or sinus present at birth and located just above the crease of the buttocks. In most cases, pilonidal dimples are benign and may just be accompanied by increased hair growth in the area. C97174 Congenital Abnormality of the Skin C89506 NICHD Newborn Screening Terminology C81288 S-Beta Thalassemia S-Beta Thalassemia A disorder characterized by the body's inability to synthesize beta-globin chains, leading to the formation of abnormal hemoglobin and anemia. This inherited autosomal recessive blood disorder is caused by germline mutation of the HBB gene. C35729 Congenital Abnormality of the Circulatory System C89506 NICHD Newborn Screening Terminology C89521 Scarf Sign Scarf Sign When testing the newborn infant for neuromuscular maturity, the "scarf sign" test is carried out by drawing the newborn's arm across the chest to the opposite shoulder until resistance is felt. In term infants, the elbow should not cross the midline of the chest. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C2962 Seizure Seizure Sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin. C4876 Symptom C89506 NICHD Newborn Screening Terminology C28421 Sex Sex The assemblage of physical properties or qualities by which male is distinguished from female; the physical difference between male and female; the distinguishing peculiarity of male or female. C25447 Characteristic C89506 NICHD Newborn Screening Terminology C25203 Shoulder Shoulder The region of the body between the neck and the upper arm. C32221 Body Part C89506 NICHD Newborn Screening Terminology C81290 Shoulder Dystocia Shoulder Dystocia Abnormal labor or childbirth due to fetal shoulder obstruction in the vaginal canal. C81236 Birth Complication C89506 NICHD Newborn Screening Terminology C81291 Sick Newborn Sick Newborn A neonate that is unwell. C16731 Newborn C89506 NICHD Newborn Screening Terminology C34383 Sickle Cell Disease Sickle Cell Disease A blood disorder characterized by the appearance of sickle-shaped red blood cells and anemia. C35729 Congenital Abnormality of the Circulatory System C89506 NICHD Newborn Screening Terminology C87120 Single Palmar Crease Single Palmar Crease A single transverse palmar crease is found in 5% of newborns and is frequently inherited as a familial trait. However, single palmar creases can be associated with Down's syndrome and other genetic disorders, or with fetal alcohol syndrome. C97174 Congenital Abnormality of the Skin C89506 NICHD Newborn Screening Terminology C87121 Situs Inversus Situs Inversus A congenital condition in which there is complete right-to-left reversal of the position of the major thoracic and abdominal organs (that is, they are arranged in a mirror image of the normal positioning). C97151 Systemic Congenital Disorder C89506 NICHD Newborn Screening Terminology C81321 Skin Color Score Skin Color Score A component of the APGAR score, it is the numerical value assigned to an assessment of the color of the skin of a neonate. 0 = pale blue; 1 = pink body and pale blue extremities; 2 = pink body and extremities. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C73425 Sleep Sleep A natural and periodic state of rest during which consciousness of the world is suspended. C19988 Organismal Process C89506 NICHD Newborn Screening Terminology C29719 Smoking History Smoking History A record of an individual's background in regard to smoking tobacco. This would include such factors as start date, end date (if applicable), number of cigarette smoked, attempts to quit, and others. C18772 Personal Medical History C89506 NICHD Newborn Screening Terminology C50746 Sneezing Sneezing A symptom consisting of the involuntary expulsion of air from the nose. C4876 Symptom C89506 NICHD Newborn Screening Terminology C81292 Social History Social History Past events that occurred between individuals and/or their communities. C18772 Personal Medical History C89506 NICHD Newborn Screening Terminology C34781 Spastic Diplegia Spastic Diplegia A type of cerebral palsy characterized by spasticity and hypertonia of the lower extremities bilaterally, particularly the legs, hips, and pelvis; this is the most common (70%) form of cerebral palsy. C34460 Cerebral Palsy C89506 NICHD Newborn Screening Terminology C89520 Square Window Square Window When testing the newborn infant for neuromuscular maturity, the "square window" test measures wrist flexibility and resistance to extensor stretching, The examiner straightens the infant's fingers and applies gentle pressure on the dorsum of the hand, close to the fingers, and then estimates the angle between the palm of the hand and the forearm. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C81322 Step Reflex Step Reflex An involuntary, primal response in the neonate to take brisk steps when the feet are placed on a surface whilst in a supported standing position. C81181 Infant Reflex C89506 NICHD Newborn Screening Terminology C35040 Strabismus Strabismus Strabismus is the intermittent or constant misalignment of an eye so that its line of vision is not pointed at the same object as the other eye. Strabismus is caused by an imbalance in the extraocular muscles which control the positioning of the eyes. Strabismus is normal in newborns but should resolve by the time the baby is 6 months old. In older children with strabismus, the brain may learn to ignore the input from one eye, and this may lead to amblyopia, a potentially permanent decrease in vision in that eye if not corrected. C35126 Vision Disorder C89506 NICHD Newborn Screening Terminology C81293 Street Number Street Number The numeric or alphabetic identifier of a building on a thoroughfare. C16495 Demographics C89506 NICHD Newborn Screening Terminology C81294 Submitting Facility Submitting Facility The hospital or medical institution that is submitting data or information. C16495 Demographics C89506 NICHD Newborn Screening Terminology C81323 Sucking Reflex Sucking Reflex An involuntary, primal response in the neonate when a nipple is placed on an infant's lips. C81181 Infant Reflex C89506 NICHD Newborn Screening Terminology C36172 Sweating Sweating The loss of a watery fluid, consisting mainly of sodium chloride and urea in solution, that is secreted by the sweat glands in the skin of mammals. C4876 Symptom C89506 NICHD Newborn Screening Terminology C4876 Symptom Symptom Subjective evidence of disease perceived by the patient. C3367 Finding C89506 NICHD Newborn Screening Terminology C87125 Syndactyly Syndactyly A congenital condition characterized by webbing between the fingers and/or toes, joining the digits together. In rare cases, the joining of the fingers or toes may involve bony fusion between the digits. Common causes include Down Syndrome and hereditary syndactyly. C89337 Congenital Abnormality of the Musculoskeletal System C89506 NICHD Newborn Screening Terminology C40978 Telephone Number Telephone Number A sequence of decimal digits (0-9) that is used for identifying a destination telephone line or other device in a telephone network. C90492 Personal Information C89506 NICHD Newborn Screening Terminology C25206 Temperature Temperature A measure of the average kinetic energy of a system of particles. Temperature may be quantified, in the context of thermodynamics, as the potential of one system to transfer thermal energy to another system until both systems reach a state of thermal equilibrium. C25447 Characteristic C89506 NICHD Newborn Screening Terminology C21514 Temporal Qualifier Temporal Qualifier Terms used to indicate units of time or other terms associated with time. C20189 Property or Attribute C89506 NICHD Newborn Screening Terminology C49236 Therapeutic Procedure Therapeutic Procedure An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process. C25218 Intervention or Procedure C89506 NICHD Newborn Screening Terminology C12799 Thorax Thorax The division of the body lying between the neck and the abdomen. C32221 Body Part C89506 NICHD Newborn Screening Terminology C85189 Thyroglossal Duct Cyst Thyroglossal Duct Cyst A congenital benign cyst arising from the remnants of the thyroglossal duct. It is usually located in the midline of the neck. C2978 Cyst C89506 NICHD Newborn Screening Terminology C64813 Thyrotropin Measurement Thyrotropin Measurement A quantitative measurement of the amount of thyrotropin present in a sample. C25294 Laboratory Procedure C89506 NICHD Newborn Screening Terminology C25207 Time Time The continuum of experience in which events pass from the future through the present to the past. C20189 Property or Attribute C89506 NICHD Newborn Screening Terminology C33788 Toe Toe One of the terminal digits of the foot. C32221 Body Part C89506 NICHD Newborn Screening Terminology C81324 Tonic Neck Reflex Tonic Neck Reflex An involuntary, primal response in the neonate in which the arm extends to follow the infant's gaze, while the opposing arm and leg flex inward. C81181 Infant Reflex C89506 NICHD Newborn Screening Terminology C81298 Total Body Length Total Body Length The total linear extent of the body. C25334 Length C89506 NICHD Newborn Screening Terminology C74794 Total Thyroxine Measurement Total Thyroxine Measurement The determination of the amount of free and bound thyroxine present in a sample. C25294 Laboratory Procedure C89506 NICHD Newborn Screening Terminology C81325 Transferase Deficiency Galactosemia Transferase Deficient Galactosemia A disorder characterized by the body's inability to metabolize galactose. This type of galactosemia is caused by germline mutations in the GALT gene which leads to the inhibition in the activity of the enzyme galactose-1-phosphate uridyl transferase. C34816 Congenital Metabolic Disorder C89506 NICHD Newborn Screening Terminology C38038 Tremor Tremor The shaking movement of the whole body or just a certain part of it, often caused by problems of the neurons responsible for muscle action. C4876 Symptom C89506 NICHD Newborn Screening Terminology C17230 Ultrasonography Ultrasound Imaging Ultrasound A technique in which high-frequency sound waves are bounced off internal organs and the echo pattern is converted into a 2 dimensional picture of the structures beneath the transducer. C18020 Diagnostic Procedure C16847 Technique C89506 NICHD Newborn Screening Terminology C87126 Umbilical Cord Prolapse Umbilical Cord Prolapse Prolapsed Cord An obstetric emergency when the umbilical cord is pushed into the vagina ahead of the baby and becomes compressed, cutting off the flow of blood to the baby. C81236 Birth Complication C89506 NICHD Newborn Screening Terminology C12326 Undescended Testis Undescended Testis The failure of one or both testes of a male fetus to descend from the abdomen into the scrotum during the late part of pregnancy. If not surgically corrected in early childhood, males may be at increased risk for testicular cancer later in life. C35107 Congenital Abnormality of the Genitourinary System C89506 NICHD Newborn Screening Terminology C25709 Unit of Measure Unit of Measure A named quantity in terms of which other quantities are measured or specified, used as a standard measurement of like kinds. C20189 Property or Attribute C89506 NICHD Newborn Screening Terminology C77606 Unit per Gram Unit per Gram An arbitrary unit of substance content expressed in unit(s) per gram. C25709 Unit of Measure C89506 NICHD Newborn Screening Terminology C30010 US State US State One of the fifty states which is a member of the federation known as the United States of America. Other US geographic areas, such as Puerto Rico and the District of Columbia, are essentially equivalent to State when used in an address. C16495 Demographics C89506 NICHD Newborn Screening Terminology C81300 Vacuum Assisted Vaginal Delivery Vacuum Assisted Vaginal Delivery The method referring to the delivery of a fetus through the vaginal canal with assistance of a vacuum extractor device. C81301 Vaginal Assisted Delivery C89506 NICHD Newborn Screening Terminology C81301 Vaginal Assisted Delivery Vaginal Assisted Delivery The method referring to the use of medical devices such as vacuum extractor or forceps to assist with the delivery of a fetus. C81303 Vaginal Delivery C89506 NICHD Newborn Screening Terminology C81302 Vaginal Birth after Cesarean Vaginal Birth after Cesarean The method referring to the delivery of a fetus through the vaginal canal after the mother has had a cesarean delivery with a previous pregnancy. C81303 Vaginal Delivery C89506 NICHD Newborn Screening Terminology C81303 Vaginal Delivery Vaginal Delivery The method referring to the delivery of a fetus through the vaginal canal. C81179 Delivery Procedure C89506 NICHD Newborn Screening Terminology C87127 Vasa Previa Vasa Previa A serious condition in which blood vessels of the umbilical cord or the placenta cross the entrance to the birth canal, beneath the fetus; this can lead to rapid fetal blood loss during labor and delivery if the blood vessels tear as the cervix dilates and the membranes rupture. C81236 Birth Complication C89506 NICHD Newborn Screening Terminology C81184 Vernier Caliper Vernier Caliper A medical device that is a combination of ruler and caliper that can measure the distance between two points. The configuration of this device permits the measurement of internal dimensions. C81182 Measurement Device C89506 NICHD Newborn Screening Terminology C12998 Vertebral Column Vertebral Column A series of bones, muscles, tendons, and other tissues reaching from the base of the skull to the tailbone. The vertebral column forms the axis of the skeleton and encloses as well as protects the spinal cord and the fluid surrounding the spinal cord. C32221 Body Part C89506 NICHD Newborn Screening Terminology C49672 Vital Signs Vital Sign Measurement A character or string that represents the vital signs examination. C18020 Diagnostic Procedure C89506 NICHD Newborn Screening Terminology C943 Vitamin K Vitamin K The term "vitamin K" refers to a group of chemically similar fat-soluble compounds called naphthoquinones: vitamin K1 (phytonadione) is found in plants and is the primary source of vitamin K for humans through dietary consumption, vitamin K2 compounds (menaquinones) are made by bacteria in the human gut, and vitamin K3 (menadione) is a water-soluble preparation available for adults only. Vitamin K is necessary for the liver to produce the coagulation factors II, VII, IX, and X, as well as the clotting factors protein C, protein S, and protein Z; vitamin K deficiency can result in deficiencies of these coagulation factors and excess bleeding. An injection of vitamin K is routinely given to newborn infants to prevent vitamin K deficiency bleeding, also known as hemorrhagic disease of the newborn. Vitamin K deficiency is rare in adults but may result from chronic malnutrition or an inability to absorb dietary vitamins. C45306 Substance C89506 NICHD Newborn Screening Terminology C87128 Watery Stool Watery Stool Frequent, loose, and watery stools are noted in most infants, even if they are fed formula, until they are six to eight weeks old; after that, the stools become firmer and less frequent. C4876 Symptom C89506 NICHD Newborn Screening Terminology C87129 Weak Breathing Weak Breathing Shallow inhalations and exhalations that indicate respiratory distress. C4876 Symptom C89506 NICHD Newborn Screening Terminology C78718 Wheezing Wheezing A symptom and a finding during physical examination, characterized by a high-pitched, whistling sound during breathing. It results from the narrowing or obstruction of the respiratory airways. The most common causes of wheezing are asthma, chronic obstructive pulmonary disease, tracheobronchitis, and pulmonary edema. C4876 Symptom C89506 NICHD Newborn Screening Terminology C87131 Yawning Yawning An involuntary deep inhalation with the mouth open, often a sign of drowsiness or boredom. C4876 Symptom C89506 NICHD Newborn Screening Terminology C49488 Yes Yes The affirmative response to a question. C25180 Indicator C89506 NICHD Newborn Screening Terminology C12664 Abdominal Cavity Abdomen The portion of the body that lies between the thorax and the pelvis. C32221 Body Part C90259 NICHD Pediatric Terminology C92921 Abdominal Pregnancy Abdominal Pregnancy Ectopic pregnancy characterized by the implantation of the embryo in the peritoneal cavity or abdominal organs. C34945 Ectopic Pregnancy C90259 NICHD Pediatric Terminology C92725 Abnormal Fetal Attitude Abnormal Fetal Attitude An abnormality in the position of the fetus during the labor and delivery process. C92713 Fetal Attitude C90259 NICHD Pediatric Terminology C92726 Abnormal Pregnancy Abnormal Pregnancy A pregnancy that is complicated and affected by an abnormal finding or disease condition in either the fetus and/or the mother. C27020 Female Reproductive System Disorder C90259 NICHD Pediatric Terminology C35221 Abortion Finding Abortion Any termination of pregnancy happening before the fetus is able to sustain independent life. C90491 Pregnancy Outcome C90259 NICHD Pediatric Terminology C92943 Active Phase of Labor Active Phase of Labor The period during the first stage of labor and childbirth involved with cervical dilatation, effacement, and fetal station. C92798 First Stage of Labor C90259 NICHD Pediatric Terminology C92621 Acute Stress Disorder Acute Stress Disorder An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by dissociative symptoms; vivid recollections of the traumatic event; avoidance of stimuli associated with the traumatic event; and a constant state of hyperarousal for no more than one month. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology C25407 Address Address A standardized representation of the location of a person, business, building, or organization. C16495 Demographics C90259 NICHD Pediatric Terminology C39298 Adolescence Adolescence The time period between the beginning of puberty and adulthood. A human life stage that begins at twelve years of age and continues until twenty-one complete years of age, generally marked by the beginning of puberty and lasting to the beginning of adulthood. C89345 Child Life Stage C90259 NICHD Pediatric Terminology C34362 Agoraphobia Agoraphobia An anxiety disorder characterized by an intense, irrational fear of venturing out into open places or situations in which help (or escape) might not be available should excessive anxiety or panic symptoms develop. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology C92727 Alcohol Related Birth Defect Alcohol Related Birth Defects A physical or cognitive mental abnormality caused by maternal alcohol consumption and its toxic effect on the developing embryo during pregnancy. C92780 Fetal Alcohol Spectrum Disorder C90259 NICHD Pediatric Terminology C92728 Alcohol Related Neurodevelopmental Disorder Alcohol Related Neurodevelopmental Disorder A cognitive and neurological disorder due to fetal intrauterine exposure to maternal alcohol consumption. Typically, this presents without facies or other growth abnormalities. C92780 Fetal Alcohol Spectrum Disorder C90259 NICHD Pediatric Terminology C81229 Alcohol Use History Alcohol Use History A description of an individual's current and past experience with alcoholic beverage consumption. C18772 Personal Medical History C90259 NICHD Pediatric Terminology C62651 Allergen Allergen A substance that elicits an allergic reaction. C45306 Substance C90259 NICHD Pediatric Terminology C3114 Hypersensitivity Allergic Reaction A local or general reaction of an organism following contact with a specific allergen to which it has been previously exposed and to which it has become sensitized. C4876 Symptom C90259 NICHD Pediatric Terminology C74732 Alpha-fetoprotein Measurement Alpha-fetoprotein Measurement The determination of the amount of alpha-fetoprotein present in a sample. C92745 Blood Test for Protein Level C90259 NICHD Pediatric Terminology C52009 Amniocentesis Amniocentesis A prenatal diagnostic procedure in which a small sample of amniotic fluid is removed from the uterus by a needle inserted into the abdomen. This procedure is used to detect various genetic abnormalities in the fetus and/or the sex of the fetus. C92803 Screening for Genetic Defect C90259 NICHD Pediatric Terminology C92729 Amnioinfusion Amnioinfusion The procedure of instilling saline or other fluids into the amniotic cavity using an intrauterine catheter. C89340 Obstetric Procedure C90259 NICHD Pediatric Terminology C13188 Amniotic Fluid Amniotic Fluid The fluid within the amniotic cavity which surrounds and protects the developing embryo. It is initially produced by the amnion and then later by the lungs and kidneys. The amount at term normally varies from 500 to 2000 ml. C13236 Biological Substance C90259 NICHD Pediatric Terminology C12219 Anatomic Structure, System, or Substance Anatomic Structure or System A human biological structure, fluid or other substance; excludes single molecular entities. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C97167 Anemia of Prematurity Anemia of Prematurity A blood disorder characterized by low hemoglobin levels in premature neonates that usually spontaneously resolves within 3-6 months post birth. A combination of factors including the transition from the liver to the bone marrow for erythropoiesis in a neonate, blood loss experienced during delivery, the shortened life span of fetal blood cells, and an acclimation to a relatively hyperoxic environment outside the womb can predispose a neonate to this condition. C35729 Congenital Abnormality of the Circulatory System C90259 NICHD Pediatric Terminology C15181 Anesthesia Procedure Anesthesia Procedure Treatment with a pharmacological substance that produces a loss of feeling. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology C92730 Angular Pregnancy Angular Pregnancy A type of pregnancy which starts with the embryo in the interstitial section of the fallopian tube, which then grows into the uterine cavity. C34945 Ectopic Pregnancy C90259 NICHD Pediatric Terminology C32078 Ankle Joint Ankle Joint A gliding joint between the distal ends of the tibia and fibula and the proximal end of the talus. C32221 Body Part C90259 NICHD Pediatric Terminology C34387 Anorexia Nervosa Anorexia Nervosa A disorder most often seen in adolescent females characterized by a refusal to maintain a minimally normal body weight, an intense fear of gaining weight, a disturbance in body image, and, in postmenarcheal females, the development of amenorrhea. C89332 Eating Disorder C90259 NICHD Pediatric Terminology C92731 Antepartum Antepartum The period of time preceding labor and delivery. C92858 Pregnancy Time Period C90259 NICHD Pediatric Terminology C92732 Anterior Occiput Presentation Anterior Occiput Occiput Anterior A fetal position during delivery in which the head of the fetus faces the mother's back. C92926 Fetal Position C90259 NICHD Pediatric Terminology C2878 Anxiety Disorder Anxiety Disorder A category of psychiatric disorders which are characterized by anxious feelings or fear often accompanied by physical symptoms associated with anxiety. C2893 Psychiatric Disorder C90259 NICHD Pediatric Terminology C73437 APGAR Score APGAR Score The numerical sum between zero and ten that is computed from individual values of zero to two that are assigned to five different areas of interest in newborn screenings. These areas are breathing, muscle tone, pulse rate, reflex irritability and skin color. C81274 Numeric Value C90259 NICHD Pediatric Terminology C81230 APGAR Test APGAR Test A test devised by Dr. Virginia Apgar to assess the overall health of a newborn upon birth. The test is administered at one and five minutes after birth and allows for the assignation of numerical values between zero and two for specific observations regarding skin color, pulse rate, reflex irritability, muscle tone and breathing. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C92733 Appropriate for Gestational Age Appropriate for Gestational Age An assessment of the fetus or the newborn infant for growth and size that is considered within normal ranges. C92711 Fetal Finding C90259 NICHD Pediatric Terminology C32141 Arm Arm The portion of the upper extremity between the shoulder and the elbow. For clinical purposes this term is also used to refer to the whole superior limb. C32221 Body Part C90259 NICHD Pediatric Terminology C90496 Arm Recoil Arm Recoil Measurement A test commonly administered to assess the physiologic response to extending the arms as straight as possible alongside the body when lying down. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C16739 Artificial Insemination Artificial Insemination Introduction of sperm into the female reproductive tract by artificial means in order to achieve fertilization. C92930 Conception Method C90259 NICHD Pediatric Terminology C92734 Artificial Rupture of Membrane Artificial Rupture of Membrane AROM An external intervention during labor and delivery to break the bag of membranes or the amniotic sac to facilitate childbirth. C92814 Induction of Labor C90259 NICHD Pediatric Terminology C97159 Asperger Syndrome Asperger Syndrome A disorder most often diagnosed in the pediatric years in which the individual displays marked impairment in social interaction and a repetitive, stereotyped pattern of behavior. The individual, however, displays no delay in language or cognitive development, which differentiates Asperger Syndrome from autism. C88412 Autism Spectrum Disorder C90259 NICHD Pediatric Terminology C92735 Assessment of Fetal Attitude Assessment of Fetal Attitude A method to find the position of the fetal head in the uterine cavity in its descent during labor. C92920 Assessment of Fetal Condition C90259 NICHD Pediatric Terminology C92920 Assessment of Fetal Condition Assessment of Fetal Condition A method to determine health status of fetus; it includes prenatal diagnostic methods and obstetrical management. C90341 Pediatric Intervention or Procedure C90259 NICHD Pediatric Terminology C92736 Assessment of Fetal Heart Condition Assessment of Fetal Heart Condition The monitoring of the fetal heart to determine the cardiac status and health of the fetus during pregnancy and labor. C92920 Assessment of Fetal Condition C90259 NICHD Pediatric Terminology C92737 Assessment of Fetal Presentation Assessment of Fetal Presentation A series of maneuvers to determine the position and presenting part of the fetus with respect to the maternal pelvic canal in preparation for labor and the birth process. C92920 Assessment of Fetal Condition C90259 NICHD Pediatric Terminology C92738 Assisted Labor Assisted Labor An intervention during the childbirth process to help the laboring mother deliver her baby. C89340 Obstetric Procedure C90259 NICHD Pediatric Terminology C97168 Ataxic Cerebral Palsy Ataxic Cerebral Palsy The least common subtype of cerebral palsy, in which the individual displays hypotonia, a loss of motor coordination, and an intention tremor. Individuals with ataxic cerebral palsy walk very unsteadily, with a wide-based gait. C34460 Cerebral Palsy C90259 NICHD Pediatric Terminology C97169 Athetoid Cerebral Palsy Athetoid Cerebral Palsy A subtype of cerebral palsy characterized by involuntary, purposeless writhing movements which affect the hands, feet, arms, and legs; the face and tongue may be affected as well, leading to involuntary grimacing, drooling, dysarthria and difficulty eating. C34460 Cerebral Palsy C90259 NICHD Pediatric Terminology C81231 Attending Health Care Provider Attending Health Care Provider The individual assigned to be the primary care manager overseeing a patient's medical care during an episode of hospitalization. C25190 Person C90259 NICHD Pediatric Terminology C97160 Attention Deficit Hyperactivity Disorder Attention Deficit Hyperactivity Disorder A disorder characterized by a marked pattern of inattention and/or hyperactivity-impulsivity that is inconsistent with developmental level and clearly interferes with functioning in at least two settings (e.g. at home and at school). At least some of the symptoms must be present before the age of 7 years. C35470 Behavioral Disorder C90259 NICHD Pediatric Terminology C62761 Attenuated Bacteria Vaccine Attenuated Live Bacterial Vaccine Any vaccine created by reducing the virulence of bacteria but still keeping the bacteria viable (live). In the production of an attenuated vaccine, the infectious agent is altered so that it becomes harmless or less virulent. This is in contrast to those vaccines produced by "killing" the pathogen (inactivated vaccine). C97116 Attenuated Live Vaccine C90259 NICHD Pediatric Terminology C97116 Attenuated Live Vaccine Attenuated Live Vaccine Any vaccine created by reducing the virulence of the infectious agent but still keeping the agent viable (live). In the production of an attenuated vaccine, the infectious agent is altered so that it becomes harmless or less virulent. This is in contrast to those vaccines produced by killing the pathogen (inactivated vaccine). C923 Vaccine C90259 NICHD Pediatric Terminology C1920 Attenuated Live Virus Vaccine Attenuated Live Virus Vaccine Live vaccines prepared from microorganisms which have undergone physical adaptation (e.g., by radiation or temperature conditioning) or serial passage in laboratory animal hosts or infected tissue/cell cultures, in order to produce avirulent mutant strains capable of inducing protective immunity. Live-attenuated vaccines are used when a CD8+ T Cell (cellular cytotoxicity) response is desired. C97116 Attenuated Live Vaccine C90259 NICHD Pediatric Terminology C38036 Audiometric Test Audiometric Test Testing conducted utilizing a manual or microprocessor audiometer to test for hearing loss. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C85573 Auscultation Auscultation Listening with a device, such as a stethoscope, to anatomical locations that produce audible sounds like the heart, lungs and abdomen. C18020 Diagnostic Procedure C90259 NICHD Pediatric Terminology C97161 Autism Autism A disorder characterized by marked impairments in social interaction and communication accompanied by a pattern of repetitive, stereotyped behaviors and activities. Developmental delays in social interaction and language surface prior to age 3 years. C88412 Autism Spectrum Disorder C90259 NICHD Pediatric Terminology C88412 Autism Spectrum Disorder Autism Spectrum Disorder A spectrum of developmental disorders that includes autism, Asperger syndrome, and Rett syndrome. Signs and symptoms include poor communication skills, defective social interactions, and repetitive behaviors. C97179 Pervasive Developmental Disorder C90259 NICHD Pediatric Terminology C92739 Back Labor Back Labor A type of labor where the labor pain or discomfort is felt by the pregnant mother in her back. C4876 Symptom C90259 NICHD Pediatric Terminology C14187 Bacteria Bacteria Unicellular, prokaryotic organisms that reproduce by cell division and usually have cell walls; can be shaped like spheres, rods or spirals and can be found in virtually any environment. C14250 Organism C90259 NICHD Pediatric Terminology C2890 Bacterial Infection Bacterial Disease An acute infectious disorder caused by gram positive or gram negative bacteria. Representative examples include pneumococcal , streptococcal, salmonella and meningeal infections. C26726 Infectious Disease C90259 NICHD Pediatric Terminology C92740 Bacterial Vaginosis Screening Bacterial Vaginosis Screen A test done during pregnancy for the presence of Gardnerella vaginalis, Ureaplasma urealyticum, Mycoplasma hominis, Mobiluncus, Prevotella and anaerobic bacteria. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C81282 Dubowitz Score Ballard/Dubowitz Score The numerical value that represents a clinical assessment of neurological and physical criteria, performed between birth and five days of age, to determine an infant's gestational age and maturity. C81274 Numeric Value C90259 NICHD Pediatric Terminology C89512 Barlow's Maneuver Barlow's Maneuver Useful in assessing for developmental dysplasia of the hip, this test is performed when the thigh is pushed posteriorly and the hip is adducted. Should the hip become dislocated by this movement, the result is considered positive. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C92741 Baseline Fetal Heart Rate Baseline Fetal Heart Rate The number of fetal cardiac beats per minute, considered as the reference value against which measurements in the future can be made. C92716 Fetal Heart Rate C90259 NICHD Pediatric Terminology C61454 Basilar Rales Basilar Rales Abnormal breath sounds (crackles) heard on auscultation only in the bases of the lungs. They indicate inflammation, fluid, or infection in the air sacs of the lung. C4876 Symptom C90259 NICHD Pediatric Terminology C81232 Bayley Scale of Infant Development Bayley Scales of Infant Development A standardized series of measurements that assesses the cognitive, motor, and behavioral development in infants and babies from one to twenty-four months of age. C81314 Newborn Behavioral Examination C90259 NICHD Pediatric Terminology C92781 Fetal Heart Beat to Beat Variability Beat to Beat Variability A fetal heart monitor finding where there is a change in the beats per minute from one fetal heart beat to the next. C92790 Fetal Heart Rate Variability C90259 NICHD Pediatric Terminology C16326 Behavior Behavior The actions or reactions of an object or organism, usually in relation to the environment or surrounding world of stimuli. C19988 Organismal Process C90259 NICHD Pediatric Terminology C81234 Behavioral Assessment Behavioral Assessment Assessment of individual responses to age appropriate stimuli. C25214 Evaluation Procedure C90259 NICHD Pediatric Terminology C81233 Behavioral Development Behavioral Development The evolution of actions, including reactions and responses to the environment, over an individual's lifespan. C17770 Maturation C90259 NICHD Pediatric Terminology C35470 Behavior-Related Disorder Behavioral Disorder A specific behavioral problem that occurs in persistent patterns and characteristic clusters and that causes clinically significant impairment. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C81235 Behavioral Rating Scale Behavioral Rating Scale A range of values designed to quantify the qualitative responses of an individual to a set of challenges. C81314 Newborn Behavioral Examination C90259 NICHD Pediatric Terminology C305 Bilirubin Bilirubin A dark orange, yellow pigment that is the product of the breakdown of iron in the blood; it is conjugated in the liver and excreted in the bile. C13236 Biological Substance C90259 NICHD Pediatric Terminology C97162 Binge Eating Disorder Binge Eating Disorder A disorder characterized by recurrent episodes of binge-eating over which the individual feels a lack of control and a sense of disgust and shame; unlike bulimia, however, there is no attempt to compensate for the binge-eating through vomiting or fasting. C89332 Eating Disorder C90259 NICHD Pediatric Terminology C307 Biological Agent Biologic Agent Biotechnology-derived pharmaceutical agents made from living organisms or their products. Includes recombinant proteins, monoclonal antibodies, and nucleic acids. C1909 Pharmacologic Substance C90259 NICHD Pediatric Terminology C13236 Body Fluid or Substance Biological Substance Material produced by living organisms; it can be a necessary constituent of, or product of an organismal process. C45306 Substance C90259 NICHD Pediatric Terminology C34423 Bipolar Disorder Bipolar Disorder A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence. C2893 Psychiatric Disorder C90259 NICHD Pediatric Terminology C25155 Birth Birth The event of being born. C92934 Labor and Delivery Process C90259 NICHD Pediatric Terminology C81236 Birth Complication Birth Complication The development of a problematic medical situation that occurs concurrently with the birth of a neonate. C92718 Finding during Childbirth Labor C90259 NICHD Pediatric Terminology C68615 Birth Date Birth Date The calendar date on which a person was born. C25164 Date C90259 NICHD Pediatric Terminology C81237 Birth Facility Birth Facility The facility which provides a setting with provisions for monitoring and delivering babies. C16495 Demographics C90259 NICHD Pediatric Terminology C81296 Birth Time Birth Time The hour, minute, and/or second at which birth occurs. C25207 Time C90259 NICHD Pediatric Terminology C76325 Birth Weight Birth Weight In humans, the weight of a neonate measured within one hour after birth. The factors influencing the birth weight include but not limited to infant sex, racial and ethnic group, maternal size and health status, concurrent diseases, parity, and nutrition, pregnancy environment and conditions, e.g. altitude of geographic area. C81328 Body Weight C90259 NICHD Pediatric Terminology C97109 Blindness Blindness The lack of vision. It is caused by neurological or physiological factors. C35126 Vision Disorder C90259 NICHD Pediatric Terminology C28133 Blood Cell Count Blood Cell Count The determination of the number of red blood cells, white blood cells, and platelets in a blood sample. C47868 Blood Test C90259 NICHD Pediatric Terminology C92744 Blood Glucose Measurement Blood Glucose Measurement A quantitative measurement for assessing the amount of glucose present in a blood sample. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C54706 Blood Pressure Blood Pressure The pressure of the circulating blood against the walls of the blood vessels. C25447 Characteristic C90259 NICHD Pediatric Terminology C81304 Blood Product Blood Product Any natural or synthetic composition that replicates the structure or function of a native component of blood. C45306 Substance C90259 NICHD Pediatric Terminology C47868 Blood Chemistry Measurement Blood Test The determination of the measured concentrations of chemical constituents of the blood by assay in a clinical laboratory. C18020 Diagnostic Procedure C90259 NICHD Pediatric Terminology C92745 Blood Protein Measurement Blood Test for Protein Level A quantitative measurement for assessing the amount of protein present in a blood sample. C47868 Blood Test C90259 NICHD Pediatric Terminology C15192 Blood Transfusion Blood Transfusion The injection of whole blood or a blood component directly into the bloodstream. C49236 Therapeutic Procedure C90259 NICHD Pediatric Terminology C61009 Blood Type Blood Type The specific reaction pattern of erythrocytes of an individual to the antisera of one blood group; e.g., the ABO blood group consists of four major blood types: O, A, B, and AB. This classification depends on the presence or absence of two major antigens: A or B. Type O occurs when neither is present and type AB when both are present. The blood type is the genetic phenotype of the individual for one blood group system and may be determined using different antisera available for testing. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C32221 Body Part Body Part Any part of an organism. C12219 Anatomic Structure or System C90259 NICHD Pediatric Terminology C81328 Body Weight Body Weight The weight of a subject. C25447 Characteristic C90259 NICHD Pediatric Terminology C76205 Bordetella pertussis Bordetella pertussis A species of bacteria within the phylum Proteobacteria consisting of gram-negative aerobic coccobacillus that are the causative agent of pertussis. C14187 Bacteria C90259 NICHD Pediatric Terminology C81305 Bottle Feeding Bottle Feeding Provision of liquid nutrition via a closed container system with a rubber like mouthpiece resembling a nipple. C81267 Feeding Method C90259 NICHD Pediatric Terminology C92742 Birth Partner Coached Method of Delivery Bradley Method A method of birth coaching in assisting the mother by her partner, to relieve her distress during labor and delivery by applying relaxation techniques and encouraging abdominal breathing. C92738 Assisted Labor C90259 NICHD Pediatric Terminology C96412 Brain Developmental Abnormality Brain Development Abnormality A group of congenital or acquired disorders that affect the normal development of the brain. C89338 Neurodevelopmental Disorder C90259 NICHD Pediatric Terminology C96413 Brain Disorder Brain Disorder A non-neoplastic or neoplastic disorder that affects the brain. C2934 Central Nervous System Disorder C90259 NICHD Pediatric Terminology C81238 Brazelton Neonatal Behavioral Assessment Scale Brazelton Neonatal Behavioral Assessment Scale An assessment tool created by Dr. T. Berry Brazelton and his colleagues to assist caregivers in determining developmental strengths and weaknesses in infants from birth to the age of two months. C81314 Newborn Behavioral Examination C90259 NICHD Pediatric Terminology C92746 Breast Engorgement Breast Engorgement A painful swelling of the breasts due to accumulation of milk in blocked lactating ducts. C92935 Postpartum Process C90259 NICHD Pediatric Terminology C25596 Breast Feeding Breast Feeding The nursing of an infant at the mother's breast. C19988 Organismal Process C90259 NICHD Pediatric Terminology C13257 Breast Milk Breast Milk Milk produced by female mammals for the purpose of feeding their young. C13236 Biological Substance C90259 NICHD Pediatric Terminology C92855 Pregnancy Breast Soreness Breast Soreness The tenderness of the breasts during pregnancy due to changes in the hormonal levels and increased breast tissue growth. C92771 Early Pregnancy Symptoms C90259 NICHD Pediatric Terminology C81306 Breathing Effort Score Breathing Effort Score A component of the APGAR score, it is the numerical value assigned to the assessment of breathing effort by a neonate. 0 = no spontaneous respirations; 1 = slow or irregular respirations or a weak cry; 2 = strong, consistent respirations with a robust cry. C81274 Numeric Value C90259 NICHD Pediatric Terminology C34438 Breech Presentation Breech Presentation A type of fetal presentation when the baby descends into the birth canal with hips, buttocks or its foot first during delivery. C92793 Malpresentation of Fetus C90259 NICHD Pediatric Terminology C90599 Bronchopulmonary Dysplasia Bronchopulmonary Dysplasia A non-neoplastic lung disorder which develops in premature neonates who have been treated with oxygen and mechanical ventilation. C97173 Congenital Abnormality of the Respiratory System C90259 NICHD Pediatric Terminology C92747 Bulging Perineum Bulging Perineum The protrusion in the perineal area during the second stage of labor. It is the characteristic sign of impending birth and is caused by increased pressure in the region. C92881 Signs of Impending Birth C90259 NICHD Pediatric Terminology C34440 Bulimia Bulimia Nervosa A disorder characterized by recurrent episodes of binge-eating over which the individual feels a lack of control; these episodes of binge-eating are followed by recurrent compensatory behavior to prevent weight gain, usually self-induced vomiting. In addition, self-evaluation is unduly influenced by body image. C89332 Eating Disorder C90259 NICHD Pediatric Terminology C92753 Cesarean Hysterectomy Caesarean Hysterectomy Surgical removal of uterus as a concurrent procedure after a cesarean delivery. C15256 Hysterectomy C90259 NICHD Pediatric Terminology C46088 Caesarian Section Caesarian Section C-Section The delivery of an infant through a surgical abdominal incision. Surgery is performed when there may be complications associated with a vaginal birth and increased risk to the mother or fetus. C81179 Delivery Procedure C90259 NICHD Pediatric Terminology C87067 Caput Succedaneum Caput Succedaneum A diffuse swelling of the scalp in a newborn, usually caused by the trauma of the scalp pushing through a narrowed cervix during birth. The swelling may extend across the midline of the scalp and may exhibit discoloration or bruising. C81236 Birth Complication C90259 NICHD Pediatric Terminology C2931 Cardiovascular Disorder Cardiovascular Disorder A non-neoplastic or neoplastic disorder affecting the heart or the vessels (arteries, veins and lymph vessels). Representative examples of non-neoplastic cardiovascular disorders are endocarditis and hypertension. Representative examples of neoplastic cardiovascular disorders are endocardial myxoma and angiosarcoma. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C81239 Cause of Death Cause of Death The circumstance or condition that results in the death of a living being. C70856 Observational Result C90259 NICHD Pediatric Terminology C81240 Cellular Telephone Number Cellular Telephone Number The sequence of numbers or characters, that when dialed, connects to a particular cellular telephone. C40978 Telephone Number C90259 NICHD Pediatric Terminology C49668 Centimeter Centimeter A basic unit of length in the former CGS version of metric system, equal to one hundredth of a meter or approximately 0.393 700 787 inch. C25709 Unit of Measure C90259 NICHD Pediatric Terminology C97170 Central Auditory Processing Disorder Central Auditory Processing Disorder A disorder characterized by impairment of the auditory processing, resulting in deficiencies in the recognition and interpretation of sounds by the brain. Causes include brain maturation delays and brain traumas or tumors. C97155 Language Disorder C90259 NICHD Pediatric Terminology C34662 Central Hearing Loss Central Hearing Loss Hearing loss caused by a problem along the pathway from the inner ear to the auditory region of the brain or in the brain itself. C35731 Hearing Loss C90259 NICHD Pediatric Terminology C2934 Central Nervous System Disorder Central Nervous System Disorder A non-neoplastic or neoplastic disorder which affects the brain and/or spinal cord. C26835 Neurologic Disorder C90259 NICHD Pediatric Terminology C87124 Central Nervous System Signs and Symptoms Central Nervous System Signs and Symptoms Signs and symptoms associated with disturbances within the central nervous system, which includes the brain, spinal cord and meninges. C4876 Symptom C90259 NICHD Pediatric Terminology C50484 Fetal Cephalhematoma Cephalhematoma A subperiosteal hemorrhage limited to the surface of one cranial bone, a usually benign condition seen in the newborn as a result of bone trauma. C81236 Birth Complication C90259 NICHD Pediatric Terminology C92748 Cephalic Presentation Cephalic Presentation A fetal position during delivery in which the head of the fetus descends into the maternal pelvis. C92724 Fetal Presentation C90259 NICHD Pediatric Terminology C92749 Cephalo-Pelvic Disproportion Cephalo-Pelvic Disproportion An abnormal condition during labor when the diameter of the fetal head is larger than the maternal pelvic canal; thus it is dangerous or impossible for the fetus to progress to a vaginal method of delivery. C81236 Birth Complication C90259 NICHD Pediatric Terminology C34460 Cerebral Palsy Cerebral Palsy A group of disorders affecting the development of movement and posture, often accompanied by disturbances of sensation, perception, cognition, and behavior. It results from damage to the fetal or infant brain. C26835 Neurologic Disorder C89328 Pediatric Disease or Disorder C90259 NICHD Pediatric Terminology C9039 Cervical Carcinoma Cervical Carcinoma A carcinoma arising from either the exocervical squamous epithelium or the endocervical glandular epithelium. The major histologic types of cervical carcinoma are: squamous carcinoma, adenocarcinoma, adenosquamous carcinoma, adenoid cystic carcinoma and undifferentiated carcinoma. C3262 Neoplasm C90259 NICHD Pediatric Terminology C92757 Contraceptive Cap Cervical Contraceptive Cap A medical device with a small rubber cap that fits over the cervix to block sperm from entering the cervical os. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C92750 Cervical Dilation Cervical Dilation A stretching and opening of the cervical os during childbirth in preparation for delivery of the baby; the diameter is measured in centimeters. C92819 Intrapartum Process C90259 NICHD Pediatric Terminology C92751 Cervical Effacement Cervical Effacement A shortening and thinning of cervix due to the action of uterine contractions during active labor to allow for fetal descent. C92819 Intrapartum Process C90259 NICHD Pediatric Terminology C3782 Cervical Intraepithelial Neoplasia Cervical Intraepithelial Neoplasia Squamous or glandular intraepithelial neoplasia that affects the cervical mucosal epithelium. There is no evidence of stromal invasion. According to the degree of cellular atypia and the associated architectural changes, it is classified as low or high grade. C3262 Neoplasm C90259 NICHD Pediatric Terminology C92754 Change in Uterine Shape Change in Uterine Shape A variation in the dimensions of the uterus. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C25447 Characteristic Characteristic The distinguishing qualities or prominent aspect of a person, object, action, process, or substance. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C97132 Chicken Pox Infection Chicken Pox A contagious childhood disorder caused by the varicella zoster virus. It is transmitted via respiratory secretions and contact with chickenpox blister contents. It presents with a vesicular skin rush, usually associated with fever, headache, and myalgias. The pruritic fluid-filled vesicles occur 10-21 days after exposure and last for 3-4 days. An additional 3-4 days of malaise follows before the affected individual feels better. An individual is contagious 1-2 days prior to the appearance of the blisters until all blisters are crusted over. Generally, healthy individuals recover without complications. C96411 Childhood Viral Disease C90259 NICHD Pediatric Terminology C92915 Varicella Zoster Virus Immunization Chickenpox Immunization The administration of a live attenuated viral vaccine to prevent herpes zoster infection. C15258 Immunization C90259 NICHD Pediatric Terminology C42708 Offspring Child A human descendant (son or daughter) of any age. C25190 Person C90259 NICHD Pediatric Terminology C90346 Behavior during Childhood Child Behavior Observed actions from individuals between 2 and 18 years of age. C16326 Behavior C90259 NICHD Pediatric Terminology C89345 Childhood Child Life Stage The time period between the beginning of infancy and the end of adolescence. A time period that begins at the beginning of the human embryonic stage and continues until the end of adolescence. C89335 Life Stage C90259 NICHD Pediatric Terminology C97163 Childhood Depression Childhood Depression Similar to depression in adults, childhood depression is characterized by a prolonged depressed or irritable mood accompanied by a significant loss of interest in activities, changes in appetite or sleep, decreased energy, feelings of worthlessness, and/or recurrent thoughts of death or suicide. C92190 Childhood Mental Disorder C90259 NICHD Pediatric Terminology C97164 Childhood Disintegrative Disorder Childhood Disintegrative Disorder A pediatric disorder characterized by normal development for at least the first two years of life followed by a severe regression in language, social interaction, bowel or bladder control, and/or motor skills. The affected individual may also exhibit repetitive and stereotyped patterns of behavior similar to autism. C97179 Pervasive Developmental Disorder C90259 NICHD Pediatric Terminology C92190 Pediatric Psychiatric Disorder Childhood Mental Disorder A category of psychiatric disorders which includes disorders most commonly identified in infancy, childhood, or adolescence. C89328 Pediatric Disease or Disorder C90259 NICHD Pediatric Terminology C84449 Pediatric Obesity Childhood Obesity Having a high amount of body fat during childhood. C89328 Pediatric Disease or Disorder C90259 NICHD Pediatric Terminology C35004 Childhood Schizophrenia Childhood Schizophrenia Schizophrenia occurring in childhood. C92190 Childhood Mental Disorder C90259 NICHD Pediatric Terminology C96411 Pediatric Viral Infection Childhood Viral Disease A viral infection that occurs during childhood. C89328 Pediatric Disease or Disorder C3439 Viral Disease C90259 NICHD Pediatric Terminology C26720 Chorioamnionitis Chorioamnionitis Inflammation of the fetal sac membranes. C27020 Female Reproductive System Disorder C90259 NICHD Pediatric Terminology C92755 Chorionic Villus Sampling Chorionic Villus Sampling The extraction of placenta tissue containing the chorionic villi from the maternal uterus in early pregnancy to screen for fetal genetic defects. C92803 Screening for Genetic Defect C90259 NICHD Pediatric Terminology C87068 Circumcision Circumcision Surgical removal of the prepuce (foreskin) of a male; the foreskin is the fold of skin covering the glans of the penis. C15329 Surgical Procedure C90259 NICHD Pediatric Terminology C25160 City City A large and densely populated urban area; a city specified in an address. C16495 Demographics C90259 NICHD Pediatric Terminology C87175 Cleft Lip Cleft Lip A congenital abnormality consisting of one or more clefts (splits) in the upper lip, which may be accompanied by a cleft palate; it is the result of the failure of the embryonic parts of the lip to fuse. C97171 Congenital Abnormality of the Digestive System C90259 NICHD Pediatric Terminology C87069 Cleft Palate Cleft Palate A congenital abnormality consisting of a fissure in the midline of the hard and/or soft palate; it is the result of the failure of the two sides of the palate to fuse during embryonic development. C97171 Congenital Abnormality of the Digestive System C90259 NICHD Pediatric Terminology C20993 Research or Clinical Assessment Tool Clinical Assessment Tool Any one of several evaluation/assessment tools used to ascertain a patient's condition or diagnosis. C25214 Evaluation Procedure C90259 NICHD Pediatric Terminology C77140 Clinical Test Result Clinical Test Result The result of a laboratory, radiologic, or other clinical test performed to determine the presence, absence, or degree of a condition. C70856 Observational Result C90259 NICHD Pediatric Terminology C34484 Clonus Clonus A form of involuntary muscular movement characterized by alternating contractions and relaxation in rapid succession. In the context of reflex testing, the ability to elicit clonus indicates injury to the nerve tracts above the point at which the reflex was initiated. C4876 Symptom C90259 NICHD Pediatric Terminology C34491 Clubbing of Fingers Clubbing of Fingers An abnormal enlargement of the terminal phalanges accompanied by increased length-wise curvature of the nails, giving the digits a club-like appearance. Clubbing has been noted with a wide variety of conditions, including pulmonary and cardiac diseases, liver disorders, and disorders of the gastrointestinal tract. C89337 Congenital Abnormality of the Musculoskeletal System C90259 NICHD Pediatric Terminology C84641 Clubfoot Clubfoot The most common congenital deformation of the foot, occurring in 1 of 1,000 live births. The most common form is talipes equinovarus, where the deformed foot is turned downward and inward sharply. C89337 Congenital Abnormality of the Musculoskeletal System C90259 NICHD Pediatric Terminology C62736 Cognitive Assessment Cognitive Assessment The examination of the cognitive capacities or deficits of an individual through the application of tests that probe that individual's ability to perform various mental activities such as perception, learning, and reasoning. C81313 Neurologic Examination C90259 NICHD Pediatric Terminology C81241 Cognitive Development Cognitive Development The evolution of an individual's problem solving skills, memory, language development, and ability to process information about their environment. C17770 Maturation C90259 NICHD Pediatric Terminology C81286 Collection Date Collection Date The date on which the sample or data was collected. C25164 Date C90259 NICHD Pediatric Terminology C81287 Collection Time Collection Time The hour, minute, and/or second at which the sample or data was collected. C25207 Time C90259 NICHD Pediatric Terminology C32348 Colostrum Colostrum A thick, protein-rich substance secreted by the breasts during the second half of pregnancy and for a few days after birth before the breast milk comes in. It contains antibodies which serve to give the baby protection from disease and also has a laxative effect on the colon which helps to expel the plug of meconium and facilitate the establishment of normal bowel movements. C13236 Biological Substance C90259 NICHD Pediatric Terminology C92756 Compound Fetal Presentation Compound Presentation A fetal position during delivery in which there are multiple fetal body parts that descends down the birth canal along with the main presenting part. Usually, this includes usually an extremity. C92793 Malpresentation of Fetus C90259 NICHD Pediatric Terminology C16465 Conception Conception Fertilization of an ovum by a spermatozoon resulting in formation of a viable zygote. C21173 Reproductive Process C90259 NICHD Pediatric Terminology C92930 Method of Conception Conception Method The process of conceiving a baby. C89340 Obstetric Procedure C90259 NICHD Pediatric Terminology C28258 Condom Condom A contraceptive device consisting of a thin rubber or latex sheath worn over the penis during intercourse. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C89329 Conduct Disorder Conduct Disorder A disorder diagnosed in childhood or adolescence age group characterized by aggressive behavior, deceitfulness, destruction of property or violation of rules that is persistent and repetitive, and within a one year period. C35470 Behavioral Disorder C90259 NICHD Pediatric Terminology C27645 Conductive Hearing Loss Conductive Hearing Loss Hearing loss caused by a problem in the outer ear or middle ear. Conductive losses usually affect all frequencies to the same degree. These losses are not usually severe. C35731 Hearing Loss C90259 NICHD Pediatric Terminology C37928 Confusion Confusion A mental state characterized by a lack of clear and orderly thought and behavior. C4876 Symptom C90259 NICHD Pediatric Terminology C2849 Congenital Abnormality Congenital Abnormality Any abnormality, anatomical or biochemical, evident at birth or during the neonatal period. C89328 Pediatric Disease or Disorder C90259 NICHD Pediatric Terminology C35729 Congenital Cardiovascular Abnormality Congenital Abnormality of the Circulatory System A heart or vascular abnormality which is inborn or present at birth. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology C97171 Congenital Gastrointestinal Disorder Congenital Abnormality of the Digestive System An abnormality of the digestive system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology C35107 Congenital Genitourinary Abnormality Congenital Abnormality of the Genitourinary System An abnormality of the genitourinary system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology C89337 Congenital Musculoskeletal Defect Congenital Abnormality of the Musculoskeletal System An abnormality of the musculoskeletal system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology C97172 Congenital Nervous System Disorder Congenital Abnormality of the Nervous System An abnormality of the nervous system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology C97173 Congenital Respiratory System Disorder Congenital Abnormality of the Respiratory System An abnormality of the respiratory system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology C97174 Congenital Skin Disorder Congenital Abnormality of the Skin A skin abnormality that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology C26734 Congenital Hypothyroidism Congenital Hypothyroidism A deficiency of thyroid hormone present at birth. The etiology can be genetic or environmental, or a combination of both; treatment is based on severity and causality. C34816 Congenital Metabolic Disorder C90259 NICHD Pediatric Terminology C34816 Congenital Metabolic Disorder Congenital Metabolic Disorder A group of disorders present at birth that involve genetic defects leading to disturbances in carbohydrate, lipid, lysosomal storage or amino acid metabolism in the body. C97151 Systemic Congenital Disorder C90259 NICHD Pediatric Terminology C1455 Conjugate Vaccine Conjugate Vaccine A category of vaccines created by covalently attaching an antigen from an organism to a carrier protein from the same organism to aid in the delivery of the immunogen. C97125 Polysaccharide Vaccine C90259 NICHD Pediatric Terminology C37932 Contraception Contraception The prevention of conception or impregnation by the use of devices or drugs or surgery. C15843 Preventive Intervention C90259 NICHD Pediatric Terminology C92758 Contraceptive Coil Contraceptive Coil Loop A medical device that is inserted into the uterus to prevent pregnancy. C42771 Intra Uterine Device C90259 NICHD Pediatric Terminology C42734 Contraceptive Device Contraceptive Device A device designed to prevent conception through local or systemic effect, such as a barrier contraceptive, an intrauterine device, or a means of preventing ovulation (e.g., birth control pill). C62103 Device C90259 NICHD Pediatric Terminology C92759 Contraceptive Implant Contraceptive Implant A drug implant that acts as a birth control device and which is inserted under the skin for drug delivery into the body. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C92760 Contraceptive Patch Contraceptive Patch A dermal patch that contains estrogen and progestin hormones for release and absorption through the skin and into the body to prevent pregnancy. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C69055 Contraceptive Sponge Contraceptive Sponge A sponge impregnated with an antispermicidal agent; it is designed to be placed into the vaginal canal to prevent live sperm from entering the uterus. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C92905 Uterine Contraction Frequency Contraction Frequency The number of uterine contractions recorded over a period of time, usually in minutes; measured from the start of one contraction to the start of the next. C70766 Quantitative Concept C90259 NICHD Pediatric Terminology C92906 Uterine Contraction Intensity Contraction Intensity The duration of an uterine contraction expressed as mmHg. C70766 Quantitative Concept C90259 NICHD Pediatric Terminology C92907 Uterine Contraction Interval Contraction Interval Relaxation Time between Uterine Contractions The time interval between uterine contractions during labor. C70766 Quantitative Concept C90259 NICHD Pediatric Terminology C92908 Uterine Contraction Stress Test Contraction Stress Test A test done to check for the fetal well being after administering oxytocin or nipple stimulus to induce uterine contractions in the mother. An external fetal heart rate monitor is used to assess the fetal heart rate in response to the uterine contractions. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C390 Contrast Agent Contrast Agent Substances administered during diagnostic procedures that allows delineation of internal structures. Contrast agents appear opaque due to the difference in absorption of X-rays or other electromagnetic waves and surrounding tissue. C45306 Substance C90259 NICHD Pediatric Terminology C92761 Cornual Pregnancy Cornual Pregnancy A type of pregnancy where the embryo develops in the cornu of uterus. C34945 Ectopic Pregnancy C90259 NICHD Pediatric Terminology C92762 Crash Caesarean Section Crash Caesarean Section An emergency cesarean section that is carried out urgently in cases of fetal distress or severe maternal complication that is life threatening to either or both of them. C46088 Caesarian Section C90259 NICHD Pediatric Terminology C81242 Crown to Rump Length Measurement Crown to Rump Length Measurement A measurement from the high prominence of the head to the low prominence of the buttocks of a fetus or embryo during ultrasound. This measurement is useful in determining gestational age. C81253 Gestational Weeks Assessment C90259 NICHD Pediatric Terminology C92763 Crowning during Childbirth Crowning The characteristic sign of impending birth during the second stage of labor. The presenting part of the head of fetus is visible and firmly rimmed by the maternal vaginal wall. C92881 Signs of Impending Birth C90259 NICHD Pediatric Terminology C26737 Cyanosis Cyanosis A bluish or purplish discoloration of the skin and mucous membranes resulting from a reduced amount of oxygenated hemoglobin in the blood. C4876 Symptom C90259 NICHD Pediatric Terminology C87065 Cyanotic Body Cyanotic Body Blue- or purplish-colored body; this is caused by excessive amounts of deoxygenated hemoglobin in the skin vessels of the body. C4876 Symptom C90259 NICHD Pediatric Terminology C87066 Cyanotic Limbs Cyanotic Limbs Blue- or purplish-colored limbs; this is caused by excessive amounts of deoxygenated hemoglobin in the skin vessels of the limbs. C4876 Symptom C90259 NICHD Pediatric Terminology C2978 Cyst Cyst A sac-like closed membranous structure that may be empty or contain fluid or amorphous material. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C92764 Cystic Fibrosis Carrier Screening Cystic Fibrosis Carrier Screening A genetic test to determine if either parent has the trait of cystic fibrosis carrier. C92803 Screening for Genetic Defect C90259 NICHD Pediatric Terminology C3724 Cystic Hygroma Cystic Hygroma Cystic Lymphangioma A benign lymphatic neoplasm usually arising from the neck and characterized by cystic dilation of the lymphatic vessels. C2978 Cyst C90259 NICHD Pediatric Terminology C49100 Data Value Data Value The information contained in a data field. It may represent a numeric quantity, a textual characterization, a date or time measurement, or some other state, depending on the nature of the attribute. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C25164 Date Date The particular day, month and year an event has happened or will happen. C21514 Temporal Qualifier C90259 NICHD Pediatric Terminology C27644 Deafness Deafness An inherited or acquired condition characterized by a partial or complete loss of hearing in one or both ears. The level of impairment varies from a mild but important loss of sensitivity to a total loss of hearing. C35731 Hearing Loss C90259 NICHD Pediatric Terminology C81244 Deceased Sibling Deceased Sibling The historical fact that a legal or consanguineous brother or sister has died. C90491 Pregnancy Outcome C90259 NICHD Pediatric Terminology C92765 Deflexed Fetal Attitude Deflexed Attitude A position of the fetus during the labor and delivery process where the fetal back is straight, the head position is deflexed and upright on the spine. C92713 Fetal Attitude C90259 NICHD Pediatric Terminology C92766 Delivery of Placenta Delivery of Placenta The natural process whereby the placenta detaches from the uterus. It occurs during the third stage of childbirth and shortly after delivery of the fetus. C92935 Postpartum Process C90259 NICHD Pediatric Terminology C81179 Birth Method of Delivery Delivery Procedure Description of the method by which a fetus is delivered. C89340 Obstetric Procedure C90259 NICHD Pediatric Terminology C16495 Demographics Demographics The statistical characterization of human populations or segments of human populations (e.g., characterization by age, sex, race, or income). C20189 Property or Attribute C90259 NICHD Pediatric Terminology C34527 Demyelinating Disorder Demyelinating Disorder A broad group of disorders that affect the myelin sheaths that cover the neurons. Myelin sheathes cover neuronal axons in the central and peripheral nervous system and function to increase travelling impulse speeds. Disruption of this sheath impairs neuronal transmission and can result in disorders such as multiple sclerosis and Guillain-Barre syndrome, among others. C26835 Neurologic Disorder C90259 NICHD Pediatric Terminology C81245 Denver Development Screening Test Denver Development Screening Test A test developed at the University of Colorado Medical Center to assess the developmental status of infants and children from birth to six years of age. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C2982 Depression Depression A melancholy feeling of sadness and despair. C2893 Psychiatric Disorder C90259 NICHD Pediatric Terminology C9011 Dermoid Cyst Dermoid Cyst A mature teratoma characterized by the presence of a cyst which is lined by mature tissue resembling the epidermis and the epidermal appendages. It occurs in the ovary, testis, and extragonadal sites including central nervous system and skin. C2978 Cyst C90259 NICHD Pediatric Terminology C92923 Development of Corpus Luteum Development of Corpus Luteum The process by which the ovarian follicle becomes the corpus luteum. It occurs after ovulation. C21173 Reproductive Process C90259 NICHD Pediatric Terminology C92561 Developmental Coordination Disorder Developmental coordination disorder Developmental Dyspraxia A disorder characterized by an impairment in the development of an individual's motor coordination skills; this impairment in motor development is not due to a medical condition. C89338 Neurodevelopmental Disorder C92190 Childhood Mental Disorder C90259 NICHD Pediatric Terminology C89330 Developmental Disorder Developmental Disorder A disorder diagnosed in childhood that is marked by either physical or mental impairment or both, which in turn affects the child from achieving age related developmental milestones. C89328 Pediatric Disease or Disorder C90259 NICHD Pediatric Terminology C90342 Developmental Milestone Developmental Milestones Physical or behavioral signs of maturation or skills gained by a developing child, which should be achieved by a given age that provide important information regarding the child's development. The milestones are different for each age range. Failure to achieve a particular milestone by a given age is indicative of developmental delay. C70856 Observational Result C90259 NICHD Pediatric Terminology C62103 Device Device An object contrived for a specific purpose. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C84669 Dextrocardia Dextrocardia A rare congenital abnormality in which the heart is located in the right side of the chest. It is associated with other congenital heart defects. C35729 Congenital Abnormality of the Circulatory System C90259 NICHD Pediatric Terminology C15220 Diagnosis Diagnosis The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation. C70856 Observational Result C90259 NICHD Pediatric Terminology C18020 Diagnostic Procedure Diagnostic Procedure Methods, procedures, and tests performed to diagnose disease, disordered function, or disability. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology C34687 Diaphragmatic Hernia Diaphragmatic Hernia A congenital or acquired weakness or opening in the diaphragm which allows abdominal contents to protrude into the chest cavity; congenital diaphragmatic hernias are caused when the embryonic diaphragm fails to fuse. C89337 Congenital Abnormality of the Musculoskeletal System C90259 NICHD Pediatric Terminology C2987 Diarrhea Diarrhea A condition of frequent and watery bowel movements. C4876 Symptom C90259 NICHD Pediatric Terminology C92767 Dilated Anus Dilated Anus A characteristic sign of impending birth where the anal opening becomes wider due to increased pressure in the perineal region during the second stage of labor. C92881 Signs of Impending Birth C90259 NICHD Pediatric Terminology C34541 Diphtheria Diphtheria A Gram-positive bacterial infection caused by Corynebacterium diphtheria. It usually involves the oral cavity, pharynx, and nasal cavity. Patients develop pseudomembranes in the affected areas and manifest signs and symptoms of an upper respiratory infection. The diphtheria toxin may cause myocarditis, polyneuritis, and other systemic effects. C2890 Bacterial Disease C90259 NICHD Pediatric Terminology C91718 Diphtheria Toxoid/Tetanus Toxoid Vaccine Adsorbed Diphtheria Toxoid/Tetanus Toxoid Vaccine Adsorbed A vaccine containing detoxified tetanus toxoid and detoxified diphtheria toxoid adsorbed on aluminum phosphate with active immunizing activity against diphtheria and tetanus. Intramuscular injection with this vaccine activates the immune system to develop antibodies against tetanus toxin and diphtheria toxin. C96398 Toxoid Vaccine C90259 NICHD Pediatric Terminology C91717 Diphtheria Toxoid/Tetanus Toxoid/Acellular Pertussis Vaccine Adsorbed Diphtheria Toxoid/Tetanus Toxoid/Acellular Pertussis Vaccine DTP vaccine A vaccine containing detoxified tetanus toxoid, detoxified diphtheria toxoid and acellular pertussis antigens, adsorbed on aluminum phosphate, with active immunizing activity against diphtheria, tetanus and pertussis. The acellular pertussis vaccine components, produced by Bordetella pertussis, are detoxified pertussis toxin (PT), filamentous hemagglutinin (FHA), pertactin (PRN) and fimbriae types 2 and 3 (FIM). Intramuscular injection with this vaccine activates the immune system to develop antibodies against tetanus toxin, diphtheria toxin and B. pertussis antigens. C2848 Polyvalent Vaccine C90259 NICHD Pediatric Terminology C97122 Diphtheria Toxoid/Tetanus Toxoid/Inactivated Pertussis Vaccine Diphtheria Toxoid/Tetanus Toxoid/Inactivated Pertussis Vaccine DTP A vaccine containing detoxified tetanus toxoid, detoxified diphtheria toxoid and inactivated pertussis antigens. C2848 Polyvalent Vaccine C90259 NICHD Pediatric Terminology C2991 Disease or Disorder Disease or Disorder Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C81273 Doctor's Information Doctor's Information A collection of information about a patient's doctor. C18772 Personal Medical History C90259 NICHD Pediatric Terminology C92768 Drug Induced Induction of Labor Drug Induced Induction of Labor Using pharmaceutical agents to influence uterine contractions and start labor during the childbirth process. C92814 Induction of Labor C90259 NICHD Pediatric Terminology C81246 Drug Use History Drug Use History A description of an individual's current and past use and/or abuse of drugs and chemicals. This includes prescription medication, illicit drugs and recreational substances. C18772 Personal Medical History C90259 NICHD Pediatric Terminology C92845 Placental Duncan Mechanism Duncan Mechanism The expulsion of the placenta with presentation of the maternal rough side first, rather than the usual fetal side of the placenta. C92935 Postpartum Process C90259 NICHD Pediatric Terminology C92769 Duration of Uterine Contraction Duration of Contraction The length of time from the beginning to the end of a single uterine contraction during the labor and childbirth process. C70766 Quantitative Concept C90259 NICHD Pediatric Terminology C97165 Dyscalculia Dyscalculia A wide group of related learning disorders characterized by difficulties with mathematics and manipulating numbers; the difficulty with math may be caused or exacerbated by visuo-spatial or language processing difficulties. C89334 Learning Disorder C90259 NICHD Pediatric Terminology C96410 Dyslexia Dyslexia A learning disorder characterized by an impairment in processing written words. Reading difficulties can include distortions, omissions or substitutions of characters. Oral and silent reading difficulties can include faulty and slow comprehension. C89334 Learning Disorder C90259 NICHD Pediatric Terminology C12394 Ear Ear A sense organ needed for the detection of sound and for establishing balance. The outer ear consists of the auricle, the ear canal as well as the tympanic membrane. The middle ear is made up of an air-filled cavity behind the tympanic membrane that contains the ossicles (malleus, incus and stapes). The inner ear is made up of the cochlea needed for hearing and the vestibular apparatus required for balance. C32221 Body Part C90259 NICHD Pediatric Terminology C87071 Ear Dimple Ear Dimple A pit or dimple in front of the ear of a newborn is a common finding; rarely, such a dimple may get infected, which will be manifested with redness and swelling and will require medical attention. C97174 Congenital Abnormality of the Skin C90259 NICHD Pediatric Terminology C89331 Early Adolescence Early Adolescence A transitional time in an individual's life between childhood and adolescence. This phase marks the start of physical, physiological and psychological changes that characterize pubertal growth and development. A human life stage that begins at twelve years of age and continues until eighteen complete years of age. This phase marks the start of physical, physiological and psychological changes that characterize pubertal growth and development. C89345 Child Life Stage C90259 NICHD Pediatric Terminology C89346 Early Childhood Early Childhood A time period in a child's life that is accepted to be approximately between 1 and 5 years of age. A human life stage that begins at two years of age and continues until five complete years of age. C89345 Child Life Stage C90259 NICHD Pediatric Terminology C92770 Early Fetal Heart Rate Deceleration Early Deceleration A decrease in the fetal heart rate that occurs in the initial stages of uterine contractions. C92789 Fetal Heart Rate Deceleration C90259 NICHD Pediatric Terminology C92924 Early Post-Partum Recovery Early Post-Partum Recovery The early stages in the recuperation process of a mother after her pregnancy and delivery. C92936 Post-Partum Recovery C90259 NICHD Pediatric Terminology C92771 Early Pregnancy Symptom Early Pregnancy Symptoms A characteristic complaint in a fertile woman that is indicative of a pregnancy. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C89332 Eating Disorder Eating Disorder A broad group of psychological disorders with abnormal eating behaviors leading to physiological effects from overeating or insufficient food intake. C2893 Psychiatric Disorder C90259 NICHD Pediatric Terminology C97166 Echolalia Echolalia A symptom of neurologic or psychiatric dysfunction in which the individual involuntarily and meaninglessly repeats a recently heard word, series of words, or a song. C97170 Central Auditory Processing Disorder C90259 NICHD Pediatric Terminology C87167 Eclampsia Eclampsia A potentially life-threatening disorder in pregnant or puerperal women manifested by convulsions in association with hypertension, edema, and/or proteinuria. C27020 Female Reproductive System Disorder C90259 NICHD Pediatric Terminology C34945 Ectopic Pregnancy Ectopic Pregnancy An abnormal pregnancy in which the egg is implanted anywhere outside the corpus uteri. C92726 Abnormal Pregnancy C90259 NICHD Pediatric Terminology C17953 Education Level Education Level An indication of the years of schooling completed in graded public, private, or parochial schools, and in colleges, universities, or professional schools. C16495 Demographics C90259 NICHD Pediatric Terminology C32497 Elbow Joint Elbow Joint A type of hinge joint located between the forearm and upper arm. C32221 Body Part C90259 NICHD Pediatric Terminology C81326 Elevated Test Result Elevated Test Result A result of a test that is higher than a previous value or a normal range of values. C77140 Clinical Test Result C90259 NICHD Pediatric Terminology C16541 Embryo Transfer Embryo Transfer Refers to a step in the process of in vitro fertilization (IVF) whereby one or several embryos are removed from an embryo culture and placed into the uterus of the female with the intent to establish a pregnancy. C92930 Conception Method C90259 NICHD Pediatric Terminology C99135 Embryonic Stage Embryonic Stage A stage of life in which an embryo is developing. The stage terminates with the complete formation of the embryo. A human life stage, during prenatal development, that begins at fertilization and typically continues until the end of eight weeks after fertilization, with full formation of the embryo. C89345 Child Life Stage C90259 NICHD Pediatric Terminology C13229 Embryonic Structure Embryonic Structure A body part, organ or organ component that is formed during the embryonic stage of life of an organism. C34144 Embryonic Structure or System C90259 NICHD Pediatric Terminology C34144 Embryologic Structure or System Embryonic Structure or System Body tissue, region, surface, cavity, fluid, organ, or collection of organs present in, or associated with, an embryo. C12219 Anatomic Structure or System C90259 NICHD Pediatric Terminology C92772 Emergency Caesarean Section Emergency Caesarean Section A cesarean section that is unanticipated and carried out during the labor process when it is determined that a vaginal method of delivery would be risky. C46088 Caesarian Section C90259 NICHD Pediatric Terminology C84687 Encephalocele Encephalocele A congenital neural tube closure defect resulting in the protrusion of the brain through a skull opening. When the protrusion includes the meninges, the term encephalomeningocele is used. C84923 Neural Tube Defect C90259 NICHD Pediatric Terminology C26920 Encephalopathy Encephalopathy A functional and/or structural disorder of the brain caused by diseases (e.g. liver disease, kidney disease), medications, chemicals, and injuries. C96413 Brain Disorder C90259 NICHD Pediatric Terminology C3009 Endocrine Disorder Endocrine System Disorder Any deviation from the normal structure or function of the endocrine system that is manifested by a characteristic set of symptoms and signs. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C3014 Endometriosis Endometriosis The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs. C27020 Female Reproductive System Disorder C90259 NICHD Pediatric Terminology C35435 Enlarging Abdomen Enlarged Abdomen Increasing girth of the mid section of an individual. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C92773 Enlarged Uterus Enlarged Uterus An increase in the overall dimensions or volume of the uterus compared to normal. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C15642 Epidural Block Epidural Block An anesthetic procedure that involves administering pharmaceutical agents into the epidural space of the spinal canal. Frequently administered agents include local anesthetics and analgesics. C64381 Regional Anesthesia Procedure C90259 NICHD Pediatric Terminology C3020 Epilepsy Epilepsy A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions. C96413 Brain Disorder C90259 NICHD Pediatric Terminology C92774 Episiotomy Episiotomy A surgical widening of the introitus by cutting into the musculature of the maternal perineum with a linear midline or oblique incision so as to facilitate vaginal childbirth. C15384 Surgical Incision C90259 NICHD Pediatric Terminology C87072 Esophageal Atresia Esophageal Atresia A congenital abnormality of the esophagus in which the upper esophagus ends as a blind pouch and does not connect with the lower esophagus; it is often accompanied by a tracheoesophageal fistula. Signs and symptoms in a newborn with this abnormality include excessive salivation, choking, coughing, and the development of cyanosis and respiratory distress when fed. C97171 Congenital Abnormality of the Digestive System C90259 NICHD Pediatric Terminology C16564 Ethnic Group Ethnic Group A social group characterized by a distinctive social and cultural tradition that is maintained from generation to generation. Members share a common history and origin and a sense of identification with the group. They have similar and distinctive features in their lifestyle habits and shared experiences. They often have a common genetic heritage which may be reflected in their experience of health and disease. C16495 Demographics C90259 NICHD Pediatric Terminology C25214 Evaluation Evaluation Procedure Systematic, objective appraisal of the significance, effectiveness, and impact of activities or condition according to specified objectives and criteria. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology C87073 Excessive Sucking Excessive Sucking A symptom of gastrointestinal dysfunction seen in neonates who have been exposed to drugs during pregnancy; often accompanied by excessive sucking of fists, fingers and thumbs. C4876 Symptom C90259 NICHD Pediatric Terminology C34599 Excoriation Excoriation A superficial traumatic injury to the skin caused most often by scratching, but also by abrasions or by a chemical or thermal burn. C4876 Symptom C90259 NICHD Pediatric Terminology C81247 Expected Date of Confinement Expected Date of Confinement The projected date of delivery for a pregnant female. C25164 Date C90259 NICHD Pediatric Terminology C92775 Extended Fetal Attitude Extended Fetal Attitude A position of the fetus during the labor and delivery process where the head is extended back. C92713 Fetal Attitude C90259 NICHD Pediatric Terminology C92776 External Fetal Rotation External Fetal Rotation External version A manual method of maneuvering the fetus from outside the mother's abdomen to convert a breech into a cephalic presentation. C81179 Delivery Procedure C90259 NICHD Pediatric Terminology C12401 Eye Eye The organ of sight or vision. C32221 Body Part C90259 NICHD Pediatric Terminology C87074 Ophthalmic Prophylaxis Eye prophylaxis The practice of placing antibiotic eye drops or ointment in a neonate's eyes after birth. C49236 Therapeutic Procedure C90259 NICHD Pediatric Terminology C92778 Face Presentation Face Presentation A fetal position during delivery in which the face of the fetus is first to descend into the birth canal. C92748 Cephalic Presentation C90259 NICHD Pediatric Terminology C78293 Fallopian Tube Obstruction Fallopian Tube Obstruction Blockage of the normal flow of the contents in the fallopian tube. C27020 Female Reproductive System Disorder C90259 NICHD Pediatric Terminology C92779 False Labor False Labor A relatively painless, irregular tightening sensation felt by the pregnant mother over the abdomen after the 28th week of pregnancy, that lasts about a minute each time C92904 Uterine Contraction C90259 NICHD Pediatric Terminology C3036 Fatigue Fatigue That state, following a period of mental or bodily activity, characterized by a lessened capacity for work and reduced efficiency or accomplishment, usually accompanied by a feeling of weariness, sleepiness, or irritability. C92771 Early Pregnancy Symptoms C90259 NICHD Pediatric Terminology C81267 Feeding Method Feeding Method A description of the technique for the manner in which a subject is administered food. C16847 Technique C90259 NICHD Pediatric Terminology C16576 Female Female A person who belongs to the sex that normally produces ova. The term is used to indicate biological sex distinctions, or cultural gender role distinctions, or both. C28421 Sex C90259 NICHD Pediatric Terminology C27020 Female Reproductive System Disorder Female Reproductive System Disorder A non-neoplastic or neoplastic disorder that affects the female genital system. Representative examples of non-neoplastic disorders include infection, endometriosis, and adenomyosis. Representative examples of neoplastic disorders include germ cell tumors, carcinoma, lymphoma, and sarcoma. C4875 Reproductive System Disorder C90259 NICHD Pediatric Terminology C16579 Fertilization Fertilization The process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronuclei. C92930 Conception Method C90259 NICHD Pediatric Terminology C92780 Fetal Alcohol Spectrum Disorder Fetal Alcohol Spectrum Disorder A group of disorders caused by a prenatal exposure to maternal consumption of alcohol leading to a range of behavioral, cognitive and neurological deficits in the offspring. It is characterized by physical growth problems, distinct facies, and varying psycho-neurological issues. C97151 Systemic Congenital Disorder C90259 NICHD Pediatric Terminology C84713 Fetal Alcohol Syndrome Fetal Alcohol Syndrome A syndrome that can develop in infants whose mothers consumed alcohol during pregnancy. Manifestations of this syndrome include low birth weight, failure to thrive, developmental defects, organ dysfunction, mental deficiencies, behavioral problems and poor motor coordination. C92780 Fetal Alcohol Spectrum Disorder C90259 NICHD Pediatric Terminology C92713 Fetal Attitude Fetal Attitude A position assumed by fetal body parts to one another (head, chest, arms and legs) in relation to the chest. C92711 Fetal Finding C90259 NICHD Pediatric Terminology C92925 Fetal Biophysical Profile Fetal Biophysical Profile A clinical scoring method to monitor fetal asphyxia using four ultrasonic observations that include fetal breathing, fetal body movements, fetal tone, and amniotic fluid volume. Also included is the non-stress test derived fetal heart rate response to fetal movements. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C92782 Fetal Bradycardia Fetal Bradycardia A decrease in the fetal heart rate below normal baseline values. C92716 Fetal Heart Rate C90259 NICHD Pediatric Terminology C92783 Fetal Descent Fetal Descent The movement of the fetus led by the presenting part into the maternal pelvic cavity during active labor. C92912 Vaginal Birth Mechanism C90259 NICHD Pediatric Terminology C50563 Fetal Distress Fetal Distress Symptoms indicative of a state of duress to a fetus while in utero. C81236 Birth Complication C90259 NICHD Pediatric Terminology C92784 Fetal Engagement Fetal Engagement A position adopted by the fetus during labor when its head moves down into the maternal pelvic cavity. C92912 Vaginal Birth Mechanism C90259 NICHD Pediatric Terminology C92714 Fetal Examination Fetal Examination A test or diagnostic examination to assess the health status and well being of the fetus. C90341 Pediatric Intervention or Procedure C90259 NICHD Pediatric Terminology C92785 Fetal Extension Fetal Extension A change in the position of the head of the fetus as it descends through the maternal pelvic cavity during labor and delivery. C92912 Vaginal Birth Mechanism C90259 NICHD Pediatric Terminology C92786 Fetal Fibronectin Test Fetal Fibronectin Test A laboratory test to detect fetal prematurity by measuring levels of fetal fibronectin from vaginal and cervical secretions. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C92711 Fetal Finding Fetal Finding Any intrauterine symptom or result related to the fetus. C70856 Observational Result C90259 NICHD Pediatric Terminology C92715 Fetal Heart Finding Fetal Heart Finding An observation of the fetal heart that may or may not be abnormal. C70856 Observational Result C90259 NICHD Pediatric Terminology C92716 Fetal Heart Rate Fetal Heart Rate The number of fetal cardiac beats per minute. C49677 Heart Rate C90259 NICHD Pediatric Terminology C92788 Fetal Heart Rate Acceleration Fetal Heart Rate Acceleration An increase in the fetal heart rate above normal baseline values for an extended period. C92715 Fetal Heart Finding C90259 NICHD Pediatric Terminology C92789 Fetal Heart Rate Deceleration Fetal Heart Rate Deceleration A decrease in the fetal heart rate less than the normal baseline values. C92715 Fetal Heart Finding C90259 NICHD Pediatric Terminology C92929 Fetal Heart Rate Monitoring Fetal Heart Rate Monitoring The act of observing and recording the fetal heart rate for determining the baseline values and any variations or other abnormal tracings. C92714 Fetal Examination C90259 NICHD Pediatric Terminology C92790 Fetal Heart Rate Variability Fetal Heart Rate Variability A fetal heart with rate changes from the normal baseline values. C92715 Fetal Heart Finding C90259 NICHD Pediatric Terminology C92791 Fetal Heart Tone Fetal Heart Tone The sounds of the fetal heart. C92715 Fetal Heart Finding C90259 NICHD Pediatric Terminology C92792 Fetal Heart Tone Location Fetal Heart Tone Location The site of fetal cardiac sounds that can be distinctly detected in relation to the maternal abdomen. C92715 Fetal Heart Finding C90259 NICHD Pediatric Terminology C50564 Fetal Hypoxia Fetal Hypoxia Hypoxia in utero, caused by conditions such as inadequate placental function (often abruptio placentae), preeclamptic toxicity, prolapse of the umbilical cord, or complications from anesthetic administration. C81236 Birth Complication C90259 NICHD Pediatric Terminology C92926 Fetal Position Fetal Position The position of the fetus in the uterus. C92711 Fetal Finding C90259 NICHD Pediatric Terminology C92927 Fetal Position above Umbilicus Fetal Position above Umbilicus A reference point for the fetal position when the fetal heart rate is detected above the mother's umbilicus. C92926 Fetal Position C90259 NICHD Pediatric Terminology C92928 Fetal Position below Umbilicus Fetal Position below Umbilicus A reference point for the fetal position when the fetal heart rate is detected below the mother's umbilicus. C92926 Fetal Position C90259 NICHD Pediatric Terminology C92724 Fetal Presentation Fetal Presentation The first part of the fetus that is visible at the cervical opening during delivery. C92711 Fetal Finding C90259 NICHD Pediatric Terminology C92794 Fetal Pulse Oximetry Fetal Pulse Oximetry A method to assess fetal oxygenation status during labor and delivery using a noninvasive reflectance pulse oximeter. C92714 Fetal Examination C90259 NICHD Pediatric Terminology C92795 Fetal Restitution Fetal Restitution The repositioning of the fetal head attitude immediately after delivery, returning to a normal position in alignment with the rest of its body. C92912 Vaginal Birth Mechanism C90259 NICHD Pediatric Terminology C89885 Fetal Stage Fetal Stage The period during which an embryo is a fetus until birth. A human life stage, during prenatal development, that typically begins at the beginning of nine weeks after fertilization (full formation of the embryo) and continues until birth. C89345 Child Life Stage C90259 NICHD Pediatric Terminology C92717 Fetal Station Fetal Station The relationship of the presenting part of the fetus to the maternal ischial spines during labor and delivery. C92711 Fetal Finding C90259 NICHD Pediatric Terminology C92796 Fetal Tachycardia Fetal Tachycardia An increase in the fetal heart rate above the normal baseline values. C92716 Fetal Heart Rate C90259 NICHD Pediatric Terminology C13235 Fetus Fetus An unborn or unhatched vertebrate in the later stages of development showing the main recognizable features of the mature being. C13229 Embryonic Structure C90259 NICHD Pediatric Terminology C3038 Fever Fever The elevation of the body's temperature above the upper limit of normal, usually taken as 37.7 degrees C. C4876 Symptom C90259 NICHD Pediatric Terminology C3367 Finding Finding Objective evidence of disease perceptible to the examining practitioner (sign) and subjective evidence of disease perceived by the patient (symptom). C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C92718 Finding during Childbirth Labor Finding during Childbirth Labor Symptom, signs, test results in a pregnant mother childbirth. C70856 Observational Result C90259 NICHD Pediatric Terminology C89343 Finnegan Score Measurement Finnegan Score Measurement A tool to evaluate neonatal abstinence syndrome (NAS), that measures the degree to which a neonate is experiencing symptoms of withdrawal due to maternal substance abuse. C89515 Neonatal Abstinence Syndrome Assessment C90259 NICHD Pediatric Terminology C81272 First Feeding First Feeding The first time that a neonate is provided nutrition. C25207 Time C90259 NICHD Pediatric Terminology C92797 First Movement First Movement An initial set of movements by the fetus that is observed by the pregnant mother. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C92798 First Stage of Labor First Stage of Labor Dilating Stage The stage of the labor and childbirth process when the uterine contractions become strong and regular with cervical effacement and complete dilation of the cervix. C92723 Stages of Labor C90259 NICHD Pediatric Terminology C92799 First Trimester First Trimester The period of gestation that ranges from the first day of the last menstrual period in a woman up to the 12th week of her pregnancy. C69121 Trimester C90259 NICHD Pediatric Terminology C81228 Five Minutes After Birth Five Minutes After Birth The actual time that is five minutes after the birth of a fetus. This period is most commonly referenced during the administration of the APGAR test. C25207 Time C90259 NICHD Pediatric Terminology C92800 Flexed Fetal Attitude Flexed Fetal Attitude A position of the fetus during the labor and delivery process where the fetal chin is in close relation to its chest; other joints are also in a flexed position. This prepares the fetus to present the smallest diameter for passage through the maternal pelvis. C92713 Fetal Attitude C90259 NICHD Pediatric Terminology C92787 Fetal Flexion Flexion A cardinal movement in labor when the head of the fetus folds towards its chest to assume the smallest anero-posterior diameter for the presenting part during delivery. C92912 Vaginal Birth Mechanism C90259 NICHD Pediatric Terminology C32621 Fontanelle Fontanelle The four gaps in the skull of a neonate or fetus where the sutures converge. The bulging or depression of the membranous soft spots can be indicative of intracranial fluid buildup or systemic dehydration. C13229 Embryonic Structure C90259 NICHD Pediatric Terminology C92801 Food Craving Food Craving An abnormal desire for eating certain foods. C92771 Early Pregnancy Symptoms C90259 NICHD Pediatric Terminology C32622 Foot Foot The structure found below the ankle joint required for locomotion. C32221 Body Part C90259 NICHD Pediatric Terminology C81248 Forceps Delivery Forceps Delivery The method referring to the delivery of a fetus through the vaginal canal with assistance of obstetrical forceps. C81301 Vaginal Assisted Delivery C90259 NICHD Pediatric Terminology C92802 Fourth Stage of Labor Fourth Stage of Labor Recovery Stage A stage during labor and childbirth that starts with the delivery of the placenta and lasts about two hours after delivering the baby. C92723 Stages of Labor C90259 NICHD Pediatric Terminology C87076 Frenulum Frenulum A small fold of tissue that limits the movements of an organ or body part; for example, the lingual frenulum connects the tongue to the floor of the mouth and restrains its movement. C32221 Body Part C90259 NICHD Pediatric Terminology C89333 Full Term Neonate Full Term Neonate An infant born after completion of the normal gestational period. C16731 Newborn C90259 NICHD Pediatric Terminology C87077 Fused Eyelid Fused Eyelid A congenital abnormality in which the margins of the upper and lower eyelids are fused together by bands of tissue. C97174 Congenital Abnormality of the Skin C90259 NICHD Pediatric Terminology C81308 Galactose Measurement Galactose Measurement The measurement of the amount of galactose in a biologic specimen. C25294 Laboratory Procedure C90259 NICHD Pediatric Terminology C81251 Galactose-1-Phosphate Uridyltransferase Measurement Galactose-1-Phosphate Uridyltransferase Measurement The measurement of the galactose-1-phosphate uridyltransferase in a biologic specimen. C25294 Laboratory Procedure C90259 NICHD Pediatric Terminology C90497 Galeazzi Test Galeazzi Test An assessment for developmental dysplasia of the hip or a leg-length discrepancy, the patient is placed in a supine position and the ankles are brought to the buttocks with the hips and knees flexed. The result is considered positive when the knees are at different heights. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C34632 Gastroenteritis Gastroenteritis An inflammatory disorder that affects the upper and lower gastrointestinal tract. Most commonly, this is attributed to viruses; however bacteria, parasites or adverse reactions can also be the culprit. Symptoms include acute diarrhea and vomiting. C2990 Gastrointestinal Disorder C90259 NICHD Pediatric Terminology C2990 Gastrointestinal Disorder Gastrointestinal Disorder A non-neoplastic or neoplastic disorder that affects the gastrointestinal tract, anus, liver, biliary system, and pancreas. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C3368 Gastrointestinal System Signs and Symptoms Gastrointestinal System Signs and Symptoms Signs and symptoms associated with disturbances within the gastrointestinal system, which includes the stomach, intestines and all associated organs that aid in digestion. C4876 Symptom C90259 NICHD Pediatric Terminology C64380 General Anesthesia Procedure General Anesthesia Procedure Actions that render a patient unconscious for the purpose of performing a diagnostic or interventional procedure. C15181 Anesthesia Procedure C90259 NICHD Pediatric Terminology C87079 General Appearance General Appearance The result of observation and overall assessment of a subject's outward aspect including appearance and movements; for example, in a human newborn general appearance includes skin color and tone, range of motion, and spontaneous movements. C25447 Characteristic C90259 NICHD Pediatric Terminology C27993 General Qualifier General Qualifier A term that helps define and render another concept unique. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C92622 Generalized Anxiety Disorder Generalized Anxiety Disorder An anxiety disorder characterized by excessive and difficult-to-control worry about a number of life situations. The worry is accompanied by restlessness, fatigue, inability to concentrate, irritability, muscle tension, and/or sleep disturbance and lasts for at least 6 months. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology C3101 Genetic Disorder Genetic Disorder Genetic Diseases are diseases in which inherited genes predispose to increased risk. The genetic disorders associated with cancer often result from an alteration or mutation in a single gene. The diseases range from rare dominant cancer family syndrome to familial tendencies in which low-penetrance genes may interact with other genes or environmental factors to induce cancer. Research may involve clinical, epidemiologic, and laboratory studies of persons, families, and populations at high risk of these disorders. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C15709 Genetic Testing Genetic Testing The process of isolating and testing the DNA of an embryo or a person to detect the presence of genetic alterations or defects that may predispose to the future development of a disease or disorder. C25294 Laboratory Procedure C90259 NICHD Pediatric Terminology C2960 Condyloma Acuminatum Genital Warts Condyloma Acuminatum A sexually transmitted papillary growth caused by the human papillomavirus. It usually arises in the skin and mucous membranes of the perianal region and external genitalia. C3439 Viral Disease C90259 NICHD Pediatric Terminology C25177 Genitalia Genitalia The external sex organs. C32221 Body Part C90259 NICHD Pediatric Terminology C81252 Gesell Developmental Schedule Gesell Developmental Schedule A scale used as an instrument to assess a child's motor and language development, as well as personal-social and adaptive behaviors. C81314 Newborn Behavioral Examination C90259 NICHD Pediatric Terminology C92804 Gestational Gestational The period of fetal development in the uterus from the start of conception until its birth. C92858 Pregnancy Time Period C90259 NICHD Pediatric Terminology C34942 Gestational Diabetes Mellitus Gestational Diabetes Diabetes that develops during pregnancy. It usually resolves after delivery. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C81253 Gestational Weeks Assessment Gestational Weeks Assessment A standard determination of fetal age; it is the number of weeks since the first day of the last menstrual period of the mother to the date of interest. C90341 Pediatric Intervention or Procedure C90259 NICHD Pediatric Terminology C26785 Goiter Goiter Enlargement of the thyroid gland usually caused by lack of iodine in the diet, hyperthyroidism, or thyroid nodules. Symptoms include difficulty in breathing and swallowing. C3009 Endocrine System Disorder C26836 Nutritional Disorder C90259 NICHD Pediatric Terminology C48155 Gram Gram The metric unit of mass equal to one thousandth of a kilogram. One gram equals approximately 15.432 grains or 0.035 273 966 ounce. C25709 Unit of Measure C90259 NICHD Pediatric Terminology C81254 Grasp Reflex Grasp Reflex An involuntary, primal response in the neonate to grasp the fingers when their palm is touched. This reflex is present until six months of age. C81181 Infant Reflex C90259 NICHD Pediatric Terminology C87168 Group B Streptococcal Infection Group B Streptococcal Infection Group B Streptococcus, also known as Streptococcus agalactiae, colonizes the vaginal and gastrointestinal tracts of up to 45% of healthy women and may infect neonates in utero or during delivery, causing neonatal sepsis in 1-2% of colonized neonates. GBS infection may also occur in nonpregnant (particularly elderly) adults with underlying medical conditions, presenting as urinary tract infection, pneumonia, or soft-tissue infection. C2890 Bacterial Disease C90259 NICHD Pediatric Terminology C92805 Group B Streptococcus Screening Group B Streptococcus Screening Screening with a swab from the vaginal and rectal areas in late pregnancy to test for the presence of Group B streptococcal infection. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C15332 Gynecological Surgical Procedure Gynecologic Surgical Procedure Surgery performed on the female reproductive system. C15329 Surgical Procedure C90259 NICHD Pediatric Terminology C80444 H1N1 Influenza H1N1 Influenza Swine flu An acute viral respiratory infection caused by a strain of influenza virus which is endemic in swine (pigs). Rarely reported in humans prior to 2009, the disease is caused by a mutated strain of swine influenza A (H1N1) virus. It is highly contagious and spreads mainly through coughing and sneezing. Signs and symptoms include fever, chills, coughing, sore throat headache, muscle ache, and generalized weakness. Antiviral medications are most effective in the first two days of the illness. C53482 Influenza C90259 NICHD Pediatric Terminology C1126 Haemophilus Influenzae B Vaccine Haemophilus Influenzae B Vaccine Hib Vaccine|PRP vaccine A vaccine against serotype b of the Gram-negative bacterium H. influenzae (Hib). Hib vaccines contain polysaccharide-protein conjugate antigens that produce greater host immune responses than first-generation purified polysaccharide vaccine. These vaccines may differ with regard to use of protein carriers, polysaccharides, diluents, and preservatives. C1455 Conjugate Vaccine C90259 NICHD Pediatric Terminology C32712 Hand Hand The distal portion of the upper extremity. It consists of the carpus, metacarpus, and digits. C32221 Body Part C90259 NICHD Pediatric Terminology C12419 Head Head The anterior and superior part of a human bearing the mouth, the brain and sensory organs. C32221 Body Part C90259 NICHD Pediatric Terminology C81255 Head Circumference Head Circumference A circumferential measurement of the head at the widest point, which is traditionally above the eyebrows. C25334 Length C90259 NICHD Pediatric Terminology C25178 Health Health Refers to a person's state of physical, mental and social well-being; usually it refers specifically to the state of being in good health, a state of complete physical, mental and social well-being, and does not consist only of the absence of disease or infirmity. In any organism health constitutes a form of homeostasis with inputs and outputs of energy and mass in approximate equilibrium allowing for growth and continued survival. In humans, a subjective feeling of well-being coming from somatic and cognitive perceptions is considered an essential component of health. C92722 Qualitative Concept C90259 NICHD Pediatric Terminology C16205 Healthcare Activity Healthcare Activity The actions of prevention, treatment, and management of illness and the preservation of mental and physical well-being through the services offered by the medical and allied health professions. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C35731 Hearing Loss Hearing Loss A partial or complete loss of hearing in one or both ears. It is classified as conductive, sensory, or central. C63711 Sensory Disorder C90259 NICHD Pediatric Terminology C84480 Heart Murmur Heart Murmur A periodic humming or blowing sound heard on auscultation of the heart that can indicate the presence of cardiac disease; murmurs are the result of vibrations caused by the turbulent flow of blood in the heart or great vessels. Murmurs are characterized according to the area of generation (mitral, aortic, tricuspid, or pulmonary) and according to the period of the cycle (systolic or diastolic). C2931 Cardiovascular Disorder C90259 NICHD Pediatric Terminology C49677 Heart Rate Heart Rate The number of heartbeats per unit of time, usually expressed as beats per minute. C81274 Numeric Value C90259 NICHD Pediatric Terminology C81309 Heart Rate Score Heart Rate Score A component of the APGAR score, it is the numerical value assigned to an assessment of the circulatory status of a neonate. 0 = no pulse; 1 = rate less than 100 beats per minute; 2 = rate greater than 100 beats per minute. C81274 Numeric Value C90259 NICHD Pediatric Terminology C87081 Heart Rhythm Heart Rhythm The recurrent, measured movements (rhythm) of a beating heart. C25447 Characteristic C90259 NICHD Pediatric Terminology C89513 Heel to Ear Measurement Heel to Ear Measurement Useful in assessing neonatal neuromuscular development, this is obtained when the infant is placed in a supine position and the infant's feet are grasped pulled toward the ipsilateral ears. The examiner measures the angle made by the arc from the table to the infant's heels; increased angle for age suggests hypotonia, and decreased angle for age suggests hypertonia. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C84750 HELLP Syndrome HELLP Syndrome A life-threatening complication of pregnancy usually occurring in women with preeclampsia or eclampsia. It is characterized by hemolytic anemia, elevated liver enzymes, and low platelet count. Signs and symptoms include headaches, nausea, vomiting, blurred vision, and upper abdominal pain. It may lead to diffuse intravascular coagulation and acute renal failure. C85021 Preeclampsia C90259 NICHD Pediatric Terminology C3085 Hemangioma Hemangioma A benign localized vascular neoplasm usually occurring in infancy and childhood. It is characterized by the formation of capillary-sized or cavernous vascular channels. The majority of cases are congenital. C2978 Cyst C90259 NICHD Pediatric Terminology C26323 Hematologic and Lymphocytic Disorder Hematological Disorder A neoplastic or non-neoplastic disorder that affects the production and proliferation of the hematopoietic cells including lymphoid cells, the synthesis of hemoglobin, and/or the mechanisms of coagulation. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C81276 Hemoglobin A to Total Hemoglobin Ratio Measurement Hemoglobin A to Total Hemoglobin Ratio Measurement The determination of the ratio of Hemoglobin A compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage. C25294 Laboratory Procedure C90259 NICHD Pediatric Terminology C81277 Hemoglobin A2 to Total Hemoglobin Ratio Measurement Hemoglobin A2 to Total Hemoglobin Ratio Measurement The determination of the ratio of Hemoglobin A2 compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage. C25294 Laboratory Procedure C90259 NICHD Pediatric Terminology C34675 Hemoglobin C Disease Hemoglobin C Disease A blood disorder characterized by the appearance of sickle-shaped red blood cells and anemia. This disorder is caused by a specific mutation in the beta-globin HBB gene, whereby a lysine is substituted for a glutamic acid at the sixth amino acid in the protein. C35729 Congenital Abnormality of the Circulatory System C90259 NICHD Pediatric Terminology C81278 Hemoglobin C to Total Hemoglobin Ratio Measurement Hemoglobin C to Total Hemoglobin Ratio Measurement The determination of the ratio of Hemoglobin C compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage. C25294 Laboratory Procedure C90259 NICHD Pediatric Terminology C64848 Hemoglobin Measurement Hemoglobin Measurement A quantitative measurement of the amount of hemoglobin present in a sample. C25294 Laboratory Procedure C90259 NICHD Pediatric Terminology C81279 Hemoglobin S to Total Hemoglobin Ratio Measurement Hemoglobin S to Total Hemoglobin Ratio Measurement The determination of the ratio of Hemoglobin S compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage. C25294 Laboratory Procedure C90259 NICHD Pediatric Terminology C34376 Hemolytic Anemia Hemolytic Anemia Anemia resulting from the premature destruction of the peripheral blood red cells. It may be congenital or it may be caused by infections, medications, or malignancies. C26323 Hematological Disorder C90259 NICHD Pediatric Terminology C87115 Hemolytic Disease of the Newborn Hemolytic Disease of the Newborn A disorder caused when there is a Rh-factor blood-type incompatibility between the mother and fetus, and the mother's immune system forms antibodies that attack the red blood cells of her unborn child. This disorder can only occur if the mother is Rh-negative and the fetus is Rh-positive. C35729 Congenital Abnormality of the Circulatory System C90259 NICHD Pediatric Terminology C3096 Hepatitis A Infection Hepatitis A Acute inflammation of the liver caused by the hepatitis A virus. It is highly contagious and usually contracted through close contact with an infected individual or their feces, contaminated food or water. C3439 Viral Disease C90259 NICHD Pediatric Terminology C29090 Hepatitis A Vaccine Hepatitis A Vaccine An inactivated virus vaccine that provides active immunization against hepatitis A virus (HAV). Immunization with hepatitis A vaccine induces the formation of anti-HAV antibodies which provide protection against hepatitis A infection. C29694 Inactivated Vaccine C90259 NICHD Pediatric Terminology C3097 Hepatitis B Infection Hepatitis B A viral infection caused by the hepatitis B virus. C3439 Viral Disease C90259 NICHD Pediatric Terminology C92806 Hepatitis B Screening Hepatitis B Screening A test performed to determine the presence or absence of hepatitis B surface antigen. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C50583 Herpes Herpes Any inflammatory skin disease caused by a herpesvirus and characterized by the formation of small vesicles in clusters. C3439 Viral Disease C90259 NICHD Pediatric Terminology C87083 Heterotaxia Heterotaxia The abnormal arrangement or position of thoracic and/or abdominal organs in relation to each other, often occurring in a right/left transposition. C97151 Systemic Congenital Disorder C90259 NICHD Pediatric Terminology C87169 High Pitched Cry High Pitched Cry A symptom in infants that could possibly indicate the presence of one of an array of medical conditions or congenital syndromes, including birth trauma, craniosynostosis, Arnold-Chiari deformity, meningitis, and cri-du-chat syndrome (deletion of the short arm of chromosome 5). C4876 Symptom C90259 NICHD Pediatric Terminology C92807 High Risk Pregnancy High Risk Pregnancy A fetal/maternal condition that is risky and portends complications for the mother and/or fetus, when compared to a normal pregnancy. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C70933 High Test Reference Range High Test Reference Range Reported upper limit of the test reference range. C38013 Range C90259 NICHD Pediatric Terminology C92859 Prenatal HIV Screening HIV Screening Testing of a pregnant mother for antibodies to the human immunodeficiency virus (HIV) in early pregnancy. Results permit management to reduce the chances of maternal transmission of HIV to the fetus. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C92808 Hormonal Contraception Hormonal Method The birth control method that utilizes external source of sex hormones to prevent pregnancy by interfering with the ovulation, fertilization or implantation of the fertilized egg in the uterus. C37932 Contraception C90259 NICHD Pediatric Terminology C92809 Hormone Imbalance Hormone Imbalance An abnormal finding indicating that the level of a particular hormone is not within the expected normal values. C3009 Endocrine System Disorder C90259 NICHD Pediatric Terminology C75387 Human Chorionic Gonadotropin Measurement Human Chorionic Gonadotropin Measurement A laboratory test to detect the amount of human chorionic gonadotropin in a biospecimen. C92949 Pregnancy Test C90259 NICHD Pediatric Terminology C14226 Human Papillomavirus Human Papilloma Virus A strain of papillomavirus that can infect the skin and mucous membranes of humans. C14283 Virus C90259 NICHD Pediatric Terminology C14338 Human Papillomavirus-16 Human Papillomavirus-16 A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce skin and mucosal epithelial lesions. Human papillomavirus-16 (HPV16) has been directly linked to cervical cancer and is significantly associated with invasiveness. Progression from low- to high-grade neoplasia is often associated with the integration of the HPV16 genome into the host chromosome. C14226 Human Papilloma Virus C90259 NICHD Pediatric Terminology C14377 Human Papillomavirus-18 Human Papillomavirus-18 A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce skin and mucosal epithelial lesions. Human papillomavirus-18 (HPV18) has been directly linked to cervical cancer and plays a role in the pathogenesis of the disease. The virus integrates its DNA at specific chromosomal locations, such as 8q24 and 12q15. The use of molecular markers for HPV18 infection may allow the identification of patients with early stage cervical cancer and those at high risk for disease recurrence. C14226 Human Papilloma Virus C90259 NICHD Pediatric Terminology C87084 Hyperemesis Gravidarum Hyperemesis Gravidarum Severe, intractable vomiting during pregnancy (usually the first trimester) accompanied by dehydration, weight loss, and electrolyte imbalances. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C50589 Hyperthermia Hyperthermia A condition that manifests with abnormally high body temperature. In hyperthermic state, the hypothalamic set-point is normal but body temperature increases and overrides the ability to lose heat, resulting from exogenous heat exposure or endogenous heat production, e.g. in heat stroke, malignant hyperthermia, endocrine hyperthermia, or neuroleptic malignant syndrome. The concept does not refer to hyperpyrexia, the state when the hypothalamic set-point is reset at a higher temperature and is physiologically regulated. C4876 Symptom C90259 NICHD Pediatric Terminology C87085 Hypertonia Hypertonia A condition of increased muscle tone manifested by increased resistance of the muscle to passive stretching. C4876 Symptom C90259 NICHD Pediatric Terminology C92810 Hypnobirthing Hypnobirthing An unique natural method of childbirth that is supported by a relaxing self-hypnosis method. C92738 Assisted Labor C90259 NICHD Pediatric Terminology C87070 Hypotonia Hypotonia A condition of decreased tone of the skeletal muscles and diminished resistance to passive stretching. C4876 Symptom C90259 NICHD Pediatric Terminology C3890 Hypoxia Hypoxia A decrease in the amount of oxygen in the body. Symptoms range from mild (impaired judgment, memory loss, impaired motor coordination) to severe (seizures and coma). C81236 Birth Complication C90259 NICHD Pediatric Terminology C15256 Hysterectomy Hysterectomy A surgical procedure to remove the uterine body (partial hysterectomy) or the uterine body and cervix (total hysterectomy). -- 2004 C15332 Gynecologic Surgical Procedure C90259 NICHD Pediatric Terminology C92811 Hysterotomy Hysterotomy A surgical incision made on the uterus to access the uterine cavity. C15384 Surgical Incision C90259 NICHD Pediatric Terminology C92812 Hysterotomy Abortion Hysterotomy Abortion A type of abortion where the product of conception is accessed through a surgical incision on the corpus uteri intended to terminate the pregnancy. C92954 Induced Abortion C90259 NICHD Pediatric Terminology C25737 Identification Identification The procedure of having an identity established. C92722 Qualitative Concept C90259 NICHD Pediatric Terminology C81289 Image Identifier Image Identifier A sequence of letters, numbers, or other characters that specifically identifies a particular image. C18772 Personal Medical History C90259 NICHD Pediatric Terminology C81256 Imaging Information Imaging Information A collection of data pertinent to a radiographic study. C18772 Personal Medical History C90259 NICHD Pediatric Terminology C15258 Immunization Immunization Inoculating an individual with either killed or live agents to prevent contraction of a disease. C15843 Preventive Intervention C90259 NICHD Pediatric Terminology C3507 Immune System Disorder Immunolymphatic System Disorder A disorder resulting from an abnormality in the immune system. -- 2003 C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C92813 Impending Labor Impending Labor The period of time prior to the beginning of childbirth labor; common signs and symptoms include nesting, anxiety, excitement, loss of mucous plug, increased urinary frequency and loose bowel movements. C21173 Reproductive Process C90259 NICHD Pediatric Terminology C16580 in vitro Fertilization In Vitro Fertilization Fertilization of an ovum outside of the body. C92930 Conception Method C90259 NICHD Pediatric Terminology C91715 Inactivated Poliovirus Vaccine Inactivated Poliovirus Vaccine A vaccine consisting of inactivated poliovirus (IPV) types 1,2 and 3, with active immunizing activity against poliomyelitis. Upon intramuscular vaccination, inactivated poliovirus vaccine (IPV) activates the immune system to develop antibodies against polioviruses. C29694 Inactivated Vaccine C90259 NICHD Pediatric Terminology C29694 Inactivated Vaccine Inactivated Vaccine A preparation of killed microorganisms that is intended to prevent or treat an infectious disease by inducing active immunity to the causative microorganism. C923 Vaccine C90259 NICHD Pediatric Terminology C48500 Inch Inch A traditional unit of length equal to 2.54 centimeters. C25709 Unit of Measure C90259 NICHD Pediatric Terminology C26906 Urinary Frequency Increased Frequency of Urination Urination at short intervals; it may result from increased urine formation, decreased bladder capacity, or lower urinary tract irritation. C92771 Early Pregnancy Symptoms C90259 NICHD Pediatric Terminology C25180 Indicator Indicator An event, entity or condition that typically characterizes a prescribed environment or situation and determines or aids in determining whether certain stated circumstances exist or criteria are satisfied. C92722 Qualitative Concept C90259 NICHD Pediatric Terminology C92954 Induced Abortion Procedure Induced Abortion A surgical or medical procedure that terminates a pregnancy by removing the fetus. C92894 Therapeutic Abortion C90259 NICHD Pediatric Terminology C92814 Induction of Labor Induction of Labor The administration of pharmaceutical agents to promote the start of labor and childbirth process. C92738 Assisted Labor C90259 NICHD Pediatric Terminology C27956 Infant Infant A young child between one month and two years of age. C42708 Child C90259 NICHD Pediatric Terminology C81249 Infant Formula Infant Formula A nutritional substitute for breast milk, usually with a foundation of cow or soy milk. C45306 Substance C90259 NICHD Pediatric Terminology C81181 Infant Reflex Infant Reflex Primitive reflex actions that newborns display in response to specific stimuli. These reflexes are involuntary and most disappear as the infant matures. C90346 Child Behavior C90259 NICHD Pediatric Terminology C89889 Infancy Infant Stage The period of life between 28 days and 13 months of age. A human life stage that begins at birth and continues until twelve complete months of age. C89345 Child Life Stage C90259 NICHD Pediatric Terminology C26726 Infectious Disorder Infectious Disease A disorder resulting from the presence and activity of a microbial, viral, or parasitic agent. It can be transmitted by direct or indirect contact. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C3836 Infertility Infertility Inability to conceive for at least one year after trying and having unprotected sex. Causes of female infertility include endometriosis, fallopian tubes obstruction, and polycystic ovary syndrome. Causes of male infertility include abnormal sperm production or function, blockage of the epididymis, blockage of the ejaculatory ducts, hypospadias, exposure to pesticides, and health related issues. C27020 Female Reproductive System Disorder C90259 NICHD Pediatric Terminology C53482 Influenza Influenza Flu An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system. C3439 Viral Disease C90259 NICHD Pediatric Terminology C96408 Influenza Vaccination Influenza Vaccination The administration of live or attenuated influenza virus for the prophylaxis of influenza. C15258 Immunization C90259 NICHD Pediatric Terminology C89514 Palmar Crease Examination Inspection of palm crease When examining the infant's palm for abnormalities, the examiner may note a single transverse palmar crease, which is found in 5% of newborns and is frequently inherited as a familial trait. However, single palmar creases can be associated with Down's syndrome and other genetic disorders, or with fetal alcohol syndrome. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C3371 Skin Disorder Integumentary System Disorder Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C97250 Intellectual Disability Intellectual Disabilities A broad category of disorders characterized by an impairment to the intelligence an individual possesses. These impairments can result from trauma, birth or disease and are not restricted to any particular age group. C96413 Brain Disorder C90259 NICHD Pediatric Terminology C92815 Intense Uterine Contraction Intensified Contraction A powerful, temporary tensing of the uterine muscles that is stronger than previously felt movements. C92904 Uterine Contraction C90259 NICHD Pediatric Terminology C87087 Intercostal Retractions Intercostal Retractions The marked inward movement of the muscles between the ribs during inhalation; they indicate that there is reduced pressure in the chest cavity and can be a sign of breathing difficulties. C4876 Symptom C90259 NICHD Pediatric Terminology C92816 Intermittent Fetal Heart Rate Deceleration Intermittent Deceleration An infrequently repeated decrease in the fetal heart rate that occurs in conjunction with a uterine contraction. C92789 Fetal Heart Rate Deceleration C90259 NICHD Pediatric Terminology C92817 Internal Fetal Rotation Internal Fetal Rotation A finding during labor, in which the occiput rotates anteriorly and the head of the fetus assumes an oblique orientation while the fetus descends through the maternal pelvis. C92718 Finding during Childbirth Labor C90259 NICHD Pediatric Terminology C32856 Internal Nare Internal Nare The inner portion of the nostrils of the nose. C32221 Body Part C90259 NICHD Pediatric Terminology C25218 Intervention or Procedure Intervention or Procedure An activity that produces an effect, or that is intended to alter the course of a disease in a patient or population. This is a general term that encompasses the medical, social, behavioral, and environmental acts that can have preventive, therapeutic, or palliative effects. C16205 Healthcare Activity C90259 NICHD Pediatric Terminology C42771 Intrauterine Device Intra Uterine Device A device usually made of plastic or metal, inserted into the uterus to prevent conception. IUCD can be a coil, loop, triangle, or T in shape; its material can be impregnated with a pharmaceutical agent. The primary action of all IUCDs is the induction of a foreign-body reaction within the endometrium. This sterile inflammatory process is toxic to gametes, primarily spermatozoa, and effectively prevents viable sperm from passing into the fallopian tubes. The copper-bearing device has an independent toxic effect on spermatozoa. The progestin-releasing devices produce changes in endometrial architecture and function that reduce the potential for implantation of a fertilized egg. The progestin effect on the cervical mucus also reduces the penetrability of sperm. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C28161 Intramuscular Route of Administration Intramuscular Route of Administration Intramuscular injection is a route of drug administration via injection into muscle tissue. Aqueous or oleaginous solutions and emulsions or suspensions may be administered. Absorption rates, delay in availability of the drug to the systemic circulation, and duration of effect are perfusion-limited, depend on molecular size of the agent, volume, and osmolarity of the drug solution, fat content of the injection site, and patient physical activity. C38291 Parenteral Route of Administration C90259 NICHD Pediatric Terminology C92818 Intrapartum Intrapartum The period of time during labor and delivery. C92858 Pregnancy Time Period C90259 NICHD Pediatric Terminology C92922 Cardiotocography Intrapartum Cardiotocography Electronic fetal monitoring|continuous cardiotocography (CTG)|intrapartum CTG The monitoring of both maternal uterine contractions and fetal heart rate during the process of labor and delivery. C92714 Fetal Examination C90259 NICHD Pediatric Terminology C92819 Intrapartum Process Intrapartum Process The process that occurs during labor and delivery. C92934 Labor and Delivery Process C90259 NICHD Pediatric Terminology C92820 Intrauterine Cordocentesis Intrauterine Cordocentesis Fetal Blood Sampling|Percutaneous Umbilical Blood Sampling (PUBS)|Umbilical Vein Sampling The retrieval of blood sample from the umbilical cord while the fetus is in utero. C16847 Technique C90259 NICHD Pediatric Terminology C80083 Fetal Growth Retardation Intrauterine Growth Retardation Fetal Growth Restriction|Fetal Growth Retardation|IUGR|Intrauterine Growth Restriction Inhibition of fetal growth resulting in the inability of the fetus to achieve its potential size. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C38276 Intravenous Route of Administration Intravenous Route of Administration Administration of a drug within or into a vein or veins. Introduction of the drug directly into venous circulation results in 100% bioavailability due to an absence of the absorption phase, provides a precise and continuous mode of drug therapy, especially for drugs with a narrow therapeutic index. C38291 Parenteral Route of Administration C90259 NICHD Pediatric Terminology C50896 Intraventricular Brain Hemorrhage Intraventricular Hemorrhage Bleeding into the brain's ventricles. C2931 Cardiovascular Disorder C90259 NICHD Pediatric Terminology C87089 Irregular Respiration Irregular Breathing A change from the normal breathing pattern in an infant, child, or adult, in terms of the amplitude and frequency of inhalations and exhalations. C4876 Symptom C90259 NICHD Pediatric Terminology C32884 Ischium Ischium The most posterior and ventral bone making up the pelvis. C32221 Body Part C90259 NICHD Pediatric Terminology C25215 Karyotype Karyotype The appearance of the chromosomal makeup of a somatic cell in an individual or species, including the number and arrangement and size and structure of the chromosomes. C15709 Genetic Testing C90259 NICHD Pediatric Terminology C32898 Knee Joint Knee Joint A joint connecting the lower part of the femur with the upper part of the tibia. The lower part of the femur and the upper part of the tibia are attached to each other by ligaments. Other structures of the knee joint include the upper part of the fibula, located below and parallel to the tibia, and the patella which moves as the knee bends. C32221 Body Part C90259 NICHD Pediatric Terminology C87090 Labial Fusion Labial Fusion Usually found in girls between 6 months and 6 years of age, this condition occurs wherein the labia grow together instead of as 2 separate folds, thereby blocking the opening of the vagina. It is caused by conditions such as repeated diaper rash, urine and stool infections, and sexual abuse. The condition often spontaneously corrects or responds to the application of estrogen cream. C35107 Congenital Abnormality of the Genitourinary System C90259 NICHD Pediatric Terminology C92743 Birthing Labor Labor The processes an individual engages in when she attempts to gives birth. C92819 Intrapartum Process C90259 NICHD Pediatric Terminology C92934 Parturition Labor and Delivery Process The process by which a mammal gives birth. C21173 Reproductive Process C90259 NICHD Pediatric Terminology C92821 Labor Pain Labor Pain The discomfort that is experienced by the pregnant mother during the childbirth process as she attempts to give birth. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C25294 Laboratory Procedure Laboratory Procedure Any procedure that involves testing or manipulating a sample of blood, urine, or other body substance in a laboratory setting. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology C36292 Laboratory Test Result Laboratory Test Result The outcome of a laboratory test. C77140 Clinical Test Result C90259 NICHD Pediatric Terminology C97155 Language Disorder Language Disorder A category of disorders characterized by an impairment in the development of an individual's language capabilities, which is in contrast to his/her non-verbal intellect. C92190 Childhood Mental Disorder C90259 NICHD Pediatric Terminology C34197 Lanugo Lanugo Fine downy hair that covers the body of a human fetus beginning in the fifth month of gestation; it is usually shed by the ninth month of gestation. C13229 Embryonic Structure C90259 NICHD Pediatric Terminology C15266 Laparotomy Laparotomy Creation of a surgical opening into the abdominal cavity. C15384 Surgical Incision C90259 NICHD Pediatric Terminology C87092 Large for Gestational Age Large for Gestational Age A fetus or infant who is larger than expected for the age or gender, or who has a birthweight greater than the 90th percentile. C25447 Characteristic C90259 NICHD Pediatric Terminology C81310 Lasso-O Measuring Tape Lasso-O Measuring Tape A measuring tape frequently used to measure head circumference in newborns. C81261 Measuring Tape C90259 NICHD Pediatric Terminology C81257 Last Menstrual Period Last Menstrual Period The first day of the female's last menstrual cycle. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C81258 Last Screening Last Screening The most recent screening. C25164 Date C90259 NICHD Pediatric Terminology C89344 Late Adolescence Late Adolescence A transitional time in an individual's life between adolescence and early adulthood. This phase includes the final stages of pubertal growth and development as well as the attainment of significant psycho-social milestones. A human life stage that begins at nineteen years of age and continues until twenty-one complete years of age. This phase includes the final stages of pubertal growth and development as well as the attainment of significant psycho-social milestones. C89345 Child Life Stage C90259 NICHD Pediatric Terminology C92822 Late Fetal Heart Rate Deceleration Late Deceleration A decrease in the fetal heart rate that occurs gradually after the peak in uterine contraction. C92789 Fetal Heart Rate Deceleration C90259 NICHD Pediatric Terminology C92823 Late Pregnancy Bleeding Late Pregnancy Bleeding An abnormal bleeding through the vagina that occurs during the last trimester of pregnancy. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C92941 Latent Phase of Labor Latent Phase of Labor The period during the first stage of labor and childbirth that precedes the active phase of labor. C92798 First Stage of Labor C90259 NICHD Pediatric Terminology C92824 Leakage of Amniotic Fluid Leakage of Amniotic Fluid The discharge of amniotic fluid vaginally due to a tear or rupture in the amniotic membrane. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C89334 Learning Disorder Learning Disorder A group of disorders that affect a person's ability to learn or process specific types of information which is in contrast to his/her apparent level of intellect. C92190 Childhood Mental Disorder C90259 NICHD Pediatric Terminology C81259 Left Ear Left Ear The organ of hearing located on the left side of the head. C32221 Body Part C90259 NICHD Pediatric Terminology C92825 Left Occiput Anterior Presentation Left Occiput Anterior A fetal position during delivery in which the head of the fetus is in the birth canal facing the area between the right hip and the spine of the mother. C92732 Anterior Occiput C90259 NICHD Pediatric Terminology C32974 Leg Leg One of the two lower extremities in humans used for locomotion and support. C32221 Body Part C90259 NICHD Pediatric Terminology C25334 Length Length The linear extent in space from one end of something to the other end, or the extent of something from beginning to end. C25447 Characteristic C90259 NICHD Pediatric Terminology C89335 Life Stage Life Stage A designation assigned to a particular period during a life cycle, generally defined by chronological parameters. C21514 Temporal Qualifier C90259 NICHD Pediatric Terminology C12220 Lip Lip Fleshy fold which surrounds the opening of the mouth. C32221 Body Part C90259 NICHD Pediatric Terminology C96402 Live Attenuated Influenza Vaccine Live Attenuated Influenza Vaccine Nasal Spray Flu Vaccine A vaccine that contains live attenuated influenza virus (LAIV) particles. This vaccine is administered intranasally for influenza prophylaxis. Not all populations are good candidates for LAIV; the very young, elderly, asthmatics and those with health impaired may be better treated with the trivalent inactivated vaccine that is administered intramuscularly. C1920 Attenuated Live Virus Vaccine C90259 NICHD Pediatric Terminology C81260 Local Anesthesia Procedure Local Anesthesia Procedure The temporary suppression of sensation at a specific region of the body by pharmacological intervention. This type of anesthesia does not induce unconsciousness in the patient. C15181 Anesthesia Procedure C90259 NICHD Pediatric Terminology C78742 Lochia Lochial Flow Vaginal discharge occurring during the post-partum period. It consists of a mixture of blood, mucus, and placental remnants. C92935 Postpartum Process C90259 NICHD Pediatric Terminology C92826 Longitudinal Fetal Presentation Longitudinal Fetal Presentation A type of fetal presentation where the fetal spine is aligned along the longitudinal axis of the uterus and descends into the birth canal during delivery. C92724 Fetal Presentation C90259 NICHD Pediatric Terminology C34724 Low Birth Weight Low Birth Weight Refers to a fetus or infant who is smaller than expected for the age or gender, or who has a birthweight less than the 10th percentile. C76325 Birth Weight C90259 NICHD Pediatric Terminology C70934 Low Test Reference Range Low Test Reference Range Reported low limit of the test reference range. C38013 Range C90259 NICHD Pediatric Terminology C97175 Low Vision Low Vision Reduced ability to perceive visual stimuli. C35126 Vision Disorder C90259 NICHD Pediatric Terminology C92827 Lower Uterine Segment Incision Lower Uterine Segment Incision A surgical incision line on the uterus that is transversely cut in relation to the lower uterine segment. C15384 Surgical Incision C90259 NICHD Pediatric Terminology C50644 Lung Overinflation Lung Overinflation Abnormal permanent enlargement of the lung air spaces distal to terminal bronchiole not resulted from wall destruction, e.g. due to loss of opposite lung. C4876 Symptom C90259 NICHD Pediatric Terminology C25381 Maiden Name Maiden Name A woman's surname before marriage. C90492 Personal Information C90259 NICHD Pediatric Terminology C34797 Malaria Malaria A protozoan infection caused by the genus Plasmodium. There are four species of Plasmodium that can infect humans: Plasmodium falciparum, vivax, ovale, and malariae. It is transmitted to humans by infected mosquitoes. Signs and symptoms include paroxysmal high fever, sweating, chills, and anemia. C27864 Parasitic Disease C90259 NICHD Pediatric Terminology C20197 Male Male A person who belongs to the sex that normally produces sperm. The term is used to indicate biological sex distinctions, cultural gender role distinctions, or both. C28421 Sex C90259 NICHD Pediatric Terminology C27019 Male Reproductive System Disorder Male Reproductive System Disorder A non-neoplastic or neoplastic disorder that affects the male genital system. Representative examples of non-neoplastic disorders include infection, testicular torsion, and undescended testis. Representative examples of neoplastic disorders include germ cell tumors, carcinoma, lymphoma, and sarcoma. C4875 Reproductive System Disorder C90259 NICHD Pediatric Terminology C92793 Fetal Malpresentation Malpresentation of Fetus An abnormal position assumed by the fetus in the birth canal during the childbirth process. C81236 Birth Complication C90259 NICHD Pediatric Terminology C92828 Maternal Fever Maternal Fever The elevation of body temperature in a pregnant mother above 38 degrees C or more than 101 degrees F, and may be indicative of an infection. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C92829 Maternal Hypotension Maternal Hypotension A decrease in the systolic blood pressure in a pregnant mother for values that are less than 25% of her normal blood pressure levels or arbitrarily, one that is less than 100 mm Hg during pregnancy. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C90337 Maternal Life Stage Maternal Life Stage The period of time during a female's reproductive years that she functions as a mother. C89335 Life Stage C90259 NICHD Pediatric Terminology C97176 Maternal Obesity Maternal Obesity Obesity in a female who has a child. C26836 Nutritional Disorder C90259 NICHD Pediatric Terminology C17770 Maturation Maturation The act, or process, of natural progression in physical and psychological maturation from a previous, lower, or embryonic stage to a later, more complex, or adult stage. C19988 Organismal Process C90259 NICHD Pediatric Terminology C96406 Rubeola Infection Measles Rubeola A highly contagious viral infection caused by the measles virus. Symptoms appear 8-12 days after exposure and include a rash, cough, fever and muscle pains that can last 4-7 days. Measles vaccines are available to provide prophylaxis, usually combined with mumps and rubella vaccines (MMR). C96411 Childhood Viral Disease C90259 NICHD Pediatric Terminology C96403 Measles/Mumps/Rubella Vaccine Measles Mumps Rubella Vaccine A trivalent vaccine containing live attenuated viruses that can cause measles, mumps and rubella. It is an injection administered subcutaneously in two separate doses. C1920 Attenuated Live Virus Vaccine C90259 NICHD Pediatric Terminology C81182 Measurement Device Measurement Device Any device used to determine the dimension of an object. C62103 Device C90259 NICHD Pediatric Terminology C81261 Measuring Tape Measuring Tape A pliable length of fabric, plastic, paper or some composite that is has incremental lengths imprinted on the surface. C81182 Measurement Device C90259 NICHD Pediatric Terminology C78743 Meconium Meconium The newborn's first intestinal discharge. It is a dark-green, thick substance composed of mucus, intestinal secretions, hair, and intestinal mucosa cells. C13236 Biological Substance C90259 NICHD Pediatric Terminology C87093 Meconium Aspiration Syndrome Meconium Aspiration Syndrome A serious condition in which a newborn breathes a mixture of meconium (the first intestinal discharge) and amniotic fluid into the lungs around the time of delivery. Meconium aspiration syndrome occurs in 5-10 percent of births and typically occurs when the infant is stressed, as when the infant is past its due date. C97173 Congenital Abnormality of the Respiratory System C90259 NICHD Pediatric Terminology C81262 Medical Record Number Medical Record Number An identifying number within an institution that is used to reference a subject's medical information. C18772 Personal Medical History C90259 NICHD Pediatric Terminology C90603 Medication Administered at Birth Medication Given at Birth Pharmacologic agents administered to a neonate at birth. C49236 Therapeutic Procedure C90259 NICHD Pediatric Terminology C26828 Meningitis Meningitis A disorder characterized by acute inflammation of the meninges of the brain and/or spinal cord. C26726 Infectious Disease C90259 NICHD Pediatric Terminology C96391 Meningococcal Conjugate Vaccine MCV4 Meningococcal Conjugate Vaccine MCV-4 A conjugate vaccine of meningococcal polysaccharide used for active immunization against invasive meningococcal disease caused by Neisseria meningiditis serogroups A, C, Y, and W-135. C1455 Conjugate Vaccine C90259 NICHD Pediatric Terminology C96519 Meningococcal Polysaccharide Vaccine MPSV4 Meningococcal Polysaccharide Vaccine MPSV-4 A polysaccharide vaccine used to prevent contraction of meningococcal meningitis. C97125 Polysaccharide Vaccine C90259 NICHD Pediatric Terminology C3231 Menopause Menopause The permanent cessation of menses, usually defined by 6 to 12 months of amenorrhea in a woman over 45 years of age. C19988 Organismal Process C90259 NICHD Pediatric Terminology C81263 Mental Development Index Mental Development Index A sequential arrangement of information pertaining to the evolution of an individual's cognitive development. C81314 Newborn Behavioral Examination C90259 NICHD Pediatric Terminology C84392 Mental Retardation Mental Retardation A developmental disorder characterized by less than average intelligence and significant limitations in adaptive behavior with onset before the age of 18. C92190 Childhood Mental Disorder C90259 NICHD Pediatric Terminology C81264 Mental Scale Mental Scale A range of values that characterizes an individual's mental development. C81314 Newborn Behavioral Examination C90259 NICHD Pediatric Terminology C87094 Micrognathism Micrognathism A congenital abnormality of the jaws (particularly the mandible) in which they are unusually small. This condition is not always pathological and may correct itself as the patient matures; however, it may also present as a birth defect in multiple syndromes. C89337 Congenital Abnormality of the Musculoskeletal System C90259 NICHD Pediatric Terminology C67405 Microinternational Unit per Milliliter Microinternational Unit per Milliliter Unit of arbitrary substance concentration (biologic activity concentration) defined as the concentration of one millionth of international unit per one milliliter of system volume. C25709 Unit of Measure C90259 NICHD Pediatric Terminology C89347 Middle Childhood Middle Childhood The time period in a child's life that is generally defined as between 5 and 10 years of life. A human life stage that begins at six years of age and continues until eleven complete years of age. C89345 Child Life Stage C90259 NICHD Pediatric Terminology C92830 Midline Longitudinal Uterine Incision Midline Longitudinal Incision A surgical incision line that extends in a midline longitudinal axis of the uterus. C15384 Surgical Incision C90259 NICHD Pediatric Terminology C92831 Mild Uterine Contraction Mild Uterine Contractions An uterine contraction that is barely felt. C92904 Uterine Contraction C90259 NICHD Pediatric Terminology C67015 Milligram per Deciliter Milligram per Deciliter A unit of mass concentration defined as the concentration of one milligram of a substance in unit volume of the mixture equal to one cubic deciliter or 100 cubic centimeters. It is also a unit of mass density (volumic mass) defined as the density of substance which mass equal to one milligram occupies the volume one cubic deciliter or 100 cubic centimeters. C25709 Unit of Measure C90259 NICHD Pediatric Terminology C64387 Millimole per Liter Millimole per Liter A unit of concentration (molarity unit) equal to one thousandth of a mole (10E-3 mole) of solute per one liter of solution. C25709 Unit of Measure C90259 NICHD Pediatric Terminology C92832 Missed Menstrual Period Missed Period The absence of a menstrual period based on the expected start date of the menstrual cycle. C92771 Early Pregnancy Symptoms C90259 NICHD Pediatric Terminology C97177 Mixed Cerebral Palsy Mixed Cerebral Palsy A subtype of cerebral palsy characterized by both the tight muscle tone of spastic cerebral palsy and the writhing, involuntary muscle movements of athetoid cerebral palsy. C34460 Cerebral Palsy C90259 NICHD Pediatric Terminology C97178 Mixed Hearing Loss Mixed Hearing Loss A combination of conductive and sensorineural losses. C35731 Hearing Loss C90259 NICHD Pediatric Terminology C41147 Modality Modality A specific manner, characteristic, pattern of application or the employment of, any therapeutic agent or method of treatment, especially involving the physical treatment of a condition. C25447 Characteristic C90259 NICHD Pediatric Terminology C81268 Molar Ratio Molar Ratio The relative number of moles of one substance to another in a chemical reaction. C25709 Unit of Measure C90259 NICHD Pediatric Terminology C92833 Montgomery Tubercle Montgomery's Tubercles A group of small sebaceous glands that secrete into the areolae of the mother's breast to lubricate the nipple during breastfeeding. C92771 Early Pregnancy Symptoms C90259 NICHD Pediatric Terminology C92937 Pregnancy Mood Swing Mood Swing The fluctuations in the mental and emotional state of an individual during pregnancy. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C92834 Morning Sickness Morning Sickness The nausea and vomiting that accompanies early pregnancy. C92771 Early Pregnancy Symptoms C90259 NICHD Pediatric Terminology C81311 Moro Reflex Moro Reflex An involuntary, primal response in the neonate to loud noise or the feeling of falling. The response is characterized by the infant's arms symmetrically spreading out to the side and then back to the midline, and involuntarily flexion of the fingers and toes. C81181 Infant Reflex C90259 NICHD Pediatric Terminology C81269 Motor Development Motor Development The evolution of physical movement over an individual's lifespan. C17770 Maturation C90259 NICHD Pediatric Terminology C5039 Motor Manifestations Motor Manifestations The presence of an alteration in the ability to move one's body or any body parts in accordance with one's intent. C4876 Symptom C90259 NICHD Pediatric Terminology C87095 Mottling Mottling A patchy appearance of the skin caused by underlying blood vessel changes. C4876 Symptom C90259 NICHD Pediatric Terminology C87096 Movement of Lip Corners Movement of Lip Corners During examination of the newborn infant, the examiner looks for symmetric movement of the lip corners. Movement of the lip corners is governed by the zygomatic major muscle. C4876 Symptom C90259 NICHD Pediatric Terminology C34213 Mucous Connective Tissue Mucous Connective Tissue Wharton's Jelly A gelatinous type of connective tissue that is found in the umbilical cord. C13236 Biological Substance C90259 NICHD Pediatric Terminology C92752 Cervical Mucus Plug Mucus Plug A mucus plug situated in the maternal cervical os during pregnancy that prevents entry of bacteria into the uterus. C13236 Biological Substance C90259 NICHD Pediatric Terminology C81271 Multiple Birth Multiple Birth A single birthing event that produces two or more offspring. C90491 Pregnancy Outcome C90259 NICHD Pediatric Terminology C87097 Multiple Gestation Multiple Gestation A pregnancy involving twins or higher-order multiple fetuses (e.g., triplets, quadruplets). C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C92931 Multiple Pregnancy Multiple Pregnancy A gestation with more than one fertilized egg implanted as a viable fetus in the uterus. C92933 Normal Pregnancy C90259 NICHD Pediatric Terminology C29888 Mumps Mumps A contagious viral infection caused by the mumps virus. Symptoms include swollen and tender parotid glands, fever, muscle aches and fatigue. Due to vaccination programs, mumps has become a rare disease. C96411 Childhood Viral Disease C90259 NICHD Pediatric Terminology C81312 Muscle Tone Score Muscle Tone Score A component of the APGAR score, it is the numerical value assigned to an assessment of the residual muscle tension of a neonate. 0 = flaccid; 1 = flexion of extremities; 2 = active motion. C81274 Numeric Value C90259 NICHD Pediatric Terminology C27574 Connective and Soft Tissue Disorder Musculoskeletal System Disorder Any deviation from the normal structure or function of the musculoskeletal or connective tissue that is manifested by a characteristic set of symptoms and signs. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C34832 Myoclonic Jerk Myoclonic Jerk A sudden, involuntary contraction of a muscle or group of muscles; these movements may develop as a symptom of a number of neurological diseases including epilepsy, Parkinson's disease, Alzheimer's disease, or Creutzfeldt-Jacob disease. C4876 Symptom C90259 NICHD Pediatric Terminology C67326 Nanogram per Deciliter Nanogram per Deciliter A unit of mass concentration defined as the concentration of one nanogram of a substance per unit volume of the mixture equal to one deciliter. The concept also refers to the unit of mass density (volumic mass) defined as the density of substance which mass equal to one nanogram occupies the volume of one deciliter. C25709 Unit of Measure C90259 NICHD Pediatric Terminology C78500 Nasal Congestion Nasal Congestion The blockage of the nasal passage due to mucosal edema. It is usually the result of a viral infection or an allergic reaction. C4876 Symptom C90259 NICHD Pediatric Terminology C87099 Nasal Flaring Nasal Flaring Enlargement of the nostrils during breathing; although there are many possible causes, it can be a sign of respiratory distress in young infants. C4876 Symptom C90259 NICHD Pediatric Terminology C38284 Nasal Route of Administration Nasal Route of Administration Administration of a drug by the way of the nose. This often results in systemic action of the agent due to absorption through the nasal mucosa. The richly supplied vascular nature of the nasal mucosa coupled with its high drug permeation makes the nasal route of administration attractive for many drugs, including proteins and peptides. C38114 Route of Administration C90259 NICHD Pediatric Terminology C92932 Natural Birth Natural Birth The process of giving birth vaginally without any surgical intervention. C90491 Pregnancy Outcome C90259 NICHD Pediatric Terminology C13063 Neck Neck The region that connects the head to the rest of the body. C32221 Body Part C90259 NICHD Pediatric Terminology C84915 Necrotizing Enterocolitis Necrotizing Enterocolitis A serious, life-threatening disorder characterized by necrotic changes affecting portions of the small and large intestine. It is usually seen in neonates, particularly premature infants. Signs and symptoms include abdominal distention and tenderness, intestinal bleeding and ileus. It may lead to cardiovascular collapse and shock. C97171 Congenital Abnormality of the Digestive System C90259 NICHD Pediatric Terminology C35450 Negative Pregnancy Test Negative Pregnancy Test A finding which indicates an individual is not pregnant. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C86605 Neisseria meningitidis Neisseria meningitidis A gram negative diplococcal bacterium that is a causative agent for meningitis and other meningococcal diseases. C14187 Bacteria C90259 NICHD Pediatric Terminology C87101 Neonatal Abstinence Syndrome Neonatal Abstinence Syndrome A constellation of signs and symptoms observable in a neonate that are consistent with maternal substance abuse or withdrawal while pregnant. C97151 Systemic Congenital Disorder C90259 NICHD Pediatric Terminology C89515 Neonatal Abstinence Syndrome Assessment Neonatal Abstinence Syndrome Assessment The measurement of the degree to which a neonate is experiencing symptoms of withdrawal due to maternal substance abuse; the score can be used to determine subsequent treatment of the infant. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C27560 Neonatal Respiratory Distress Syndrome Neonatal Respiratory Distress Syndrome A condition of the newborn marked by dyspnea with cyanosis, most frequently occurring in premature infants, children of diabetic mothers and infants delivered by cesarean section, and sometimes with no predisposing cause. C97173 Congenital Abnormality of the Respiratory System C90259 NICHD Pediatric Terminology C89887 Full Term Neonatal Stage Neonatal Stage Term Neonatal Stage The period at birth when a newborn is born after the full gestational period. A human life stage that begins at full term birth and continues until twenty-seven complete days of age. C89345 Child Life Stage C90259 NICHD Pediatric Terminology C3262 Neoplasm Neoplasm A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C84923 Neural Tube Defect Neural Tube Defect A congenital defect characterized by failure of the neural tube to close completely; this results in the presence of openings in the brain or spinal cord. Examples of neural tube defects include encephalocele and spina bifida. C97172 Congenital Abnormality of the Nervous System C90259 NICHD Pediatric Terminology C89338 Neurodevelopmental Disorder Neurodevelopmental Disorder A childhood affliction that has a neurological basis and manifests as a developmental disability. C89330 Developmental Disorder C90259 NICHD Pediatric Terminology C26835 Nervous System Disorder Neurologic Disorder A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C81313 Neurologic Examination Neurologic Examination The assessment of the functionality of the brain, spinal column, and nerves. C18020 Diagnostic Procedure C90259 NICHD Pediatric Terminology C89339 Neurological Screening Neurological Screening A specific type of neurologic examination for early detection of disease(s) and/or disorder(s). C81313 Neurologic Examination C90259 NICHD Pediatric Terminology C89516 Neuromuscular Maturity Assessment Neuromuscular Maturity Assessment An examination of the following neonatal attributes: 1) posture; 2) the "square window" (how far the baby's hands can be flexed toward the wrist); 3) arm recoil; 4) "popliteal angle" (how far the baby's knees extend); 5) "scarf sign" (how far the baby's elbows can be moved across the chest); and 6) "heel to ear" (how far the baby's feet can be moved to the ears). It is a subscore of the Dubowitz/Ballard Examination for Gestational Age. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C92835 Neutral Fetal Attitude Neutral Fetal Attitude A position of the fetus during the labor and delivery process where the fetal chin is mildly flexed but with a forward facing head. C92713 Fetal Attitude C90259 NICHD Pediatric Terminology C16731 Newborn Newborn An infant during the first month after birth. C42708 Child C90259 NICHD Pediatric Terminology C81314 Newborn Behavioral Examination Newborn Behavioral Examination The assessment of behavior in neonates. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C87105 Newborn Blood Pressure Newborn Blood Pressure The systolic and diastolic blood pressure of the newborn upon examination; the normal range of the systolic blood pressure is 60 - 90, while the normal range of the diastolic blood pressure is 20-60. C81274 Numeric Value C90259 NICHD Pediatric Terminology C84749 Newborn Examination Newborn Examination A general assessment of the overall health of a newborn. C90341 Pediatric Intervention or Procedure C90259 NICHD Pediatric Terminology C87103 Newborn Heart Rate Newborn Heart Rate The number of heartbeats of the newborn per minute; the normal range is 100 - 180 heartbeats per minute. C49677 Heart Rate C90259 NICHD Pediatric Terminology C81270 Newborn Motor Scale Newborn Motor Scale A range of values used to quantify newborn motor development. C81274 Numeric Value C90259 NICHD Pediatric Terminology C87104 Newborn Respiratory Rate Newborn Respiratory Rate The number of inhalations and exhalations of the newborn per minute; the normal range is 30 - 60 breaths per minute. C49678 Respiratory Rate C90259 NICHD Pediatric Terminology C81178 Newborn Screening Newborn Screening A specific type of newborn examination performed to allow for early detection of disease(s) and/or disorder(s). C84749 Newborn Examination C90259 NICHD Pediatric Terminology C96388 NICHD Childhood Immunization Terminology NICHD Childhood Immunization Terminology Terminology for concepts associated with immunization in children (birth to 21 years of age) contributed by the National Institute of Child Health and Human Development. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C97150 NICHD Neurological Development Terminology NICHD Neurological Development Terminology Terminology for concepts associated with neurological development in children contributed by the National Institute of Child Health and Human Development. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C89506 NICHD Newborn Screening Terminology NICHD Newborn Screening Terminology Terminology for concepts associated with neonatal and infant examination contributed by the National Institute of Child Health and Human Development. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C92712 NICHD Pregnancy and Childbirth Terminology NICHD Pregnancy & Childbirth Terminology Terminology for concepts associated with Pregnancy, Labor and Delivery contributed by the National Institute of Child Health and Human Development. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C49487 No No The non-affirmative response to a question. C25180 Indicator C90259 NICHD Pediatric Terminology C92836 Obstetric Non-Stress Test Non-Stress Test A non-invasive test usually done during the third trimester to check for fetal well being. It is performed using an external fetal heart rate monitor to assess the fetal heart rate response to fetal movements. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C92933 Normal Pregnancy Normal Pregnancy A pregnancy that is normal for both the mother and the fetus. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C78727 Normal Reference Range Normal Reference Range Reported values within the typical or expected range. C38013 Range C90259 NICHD Pediatric Terminology C94835 Normal Spontaneous Vaginal Delivery Normal Spontaneous Vaginal Delivery Normal Delivery A process of birthing whereby the fetus is born unaided by medical inducements or surgical intervention and without complication. C81303 Vaginal Delivery C90259 NICHD Pediatric Terminology C92891 Subdermal Birth Control Implant Norplant Subdermal Birth Control Implant A subdermal implant incorporating silastic tubing containing levonorgestrel designed to administer a continuous dose of progestins for pregnancy contraception. C92759 Contraceptive Implant C90259 NICHD Pediatric Terminology C12756 Nose Nose A structure of special sense serving as an organ of the sense of smell and as an entrance to the respiratory tract. C32221 Body Part C90259 NICHD Pediatric Terminology C92837 Nuchal Translucency Screen Nuchal Translucency Screen nuchal fold scan An ultrasonic examination of the fetus to confirm gestational age by assessing and measuring for the clear space at the back of the fetal neck using external calipers. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C81274 Numeric Value Numeric Value Information in the form of a numeral contained in a data field. C49100 Data Value C90259 NICHD Pediatric Terminology C28294 Nutrition Nutrition That which is consumed to fuel necessary life processes of an organism. C19988 Organismal Process C90259 NICHD Pediatric Terminology C26836 Nutritional Disorder Nutritional Disorder Any condition related to a disturbance between proper intake and utilization of nourishment. C9229 Systemic Disorder C90259 NICHD Pediatric Terminology C92838 Oblique Fetal Presentation Oblique Fetal Presentation A fetal position during delivery in which the spine of the fetus is not aligned with the mother's resulting in the descent into the birth canal in an oblique position. C92724 Fetal Presentation C90259 NICHD Pediatric Terminology C25598 Observation Observation Watching something and taking note of what happens. C18020 Diagnostic Procedure C90259 NICHD Pediatric Terminology C70856 Observation Result Observational Result An outcome of observation represented as a text, qualitative, or quantitative parameter, code, image, graph, etc. C3367 Finding C90259 NICHD Pediatric Terminology C88411 Obsessive Compulsive Disorder Obsessive-Compulsive Disorder A disorder characterized by the presence of persistent and recurrent irrational thoughts (obsessions), resulting in marked anxiety and repetitive excessive behaviors (compulsions) as a way to try to decrease that anxiety. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology C89340 Obstetric Procedure Obstetric Procedure Any pregnancy or childbirth related procedure associated with a mother during her reproductive years. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology C92839 Oligohydramnios Oligohydramnios A lower than normal volume of amniotic fluid observed by ultrasound during pregnancy. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C81227 One Minute After Birth One Minute After Birth The actual time that is one minute after the birth of a fetus. This period is most commonly referenced during the administration of the APGAR test. C25207 Time C90259 NICHD Pediatric Terminology C15291 Oophorectomy Oophorectomy Partial or complete removal of one or both of the ovaries. C15332 Gynecologic Surgical Procedure C90259 NICHD Pediatric Terminology C12421 Oral Cavity Oral Cavity The cavity located at the upper end of the alimentary canal, behind the teeth and gums that is bounded on the outside by the lips, above by the hard and soft palates and below by the tongue. C32221 Body Part C90259 NICHD Pediatric Terminology C389 Oral Contraceptive Oral Contraceptive Pill An agent taken orally to prevent conception. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C96401 Oral Polio Vaccine Oral Polio Vaccine A vaccine that contains live attenuated polio virus. It is administered orally as polio prophylaxis in many areas of the world, but not in the U.S. since 2000. C1920 Attenuated Live Virus Vaccine C90259 NICHD Pediatric Terminology C38288 Oral Route of Administration Oral Route of Administration The introduction of a substance to the mouth or into the gastrointestinal tract by the way of the mouth, usually for systemic action. It is the most common, convenient, and usually the safest and least expensive route of drug administration, but it uses the most complicated pathway to the tissues and bioavailability varies. The disadvantages of method are hepatic first pass metabolism and enzymatic degradation of the drug within the gastrointestinal tract. This prohibits oral administration of certain classes of drugs especially peptides and proteins. C38114 Route of Administration C90259 NICHD Pediatric Terminology C14250 Organism Organism A living entity. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C19988 Organismal Process Organismal Process A biologic function, activity, or process involving either specialized organ functions, individual organs, organ systems, body parts, or whole organisms. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C89517 Ortolani Maneuver Ortolani Maneuver When testing for congenital dislocation of the hip, this is the result obtained when the examiner gently abducts the hip while pushing upward on the greater trochanter. If the hip is dislocated, it will relocate with an audible clunk, which is a positive result for this test. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C17649 Other Other Different than the one(s) previously specified or mentioned. C27993 General Qualifier C90259 NICHD Pediatric Terminology C48519 Ounce Ounce The traditional unit of mass. The avoirdupois ounce is equal to 1/16 pound, or 28.3495 grams, or 0.911 457 troy ounce. C25709 Unit of Measure C90259 NICHD Pediatric Terminology C92945 Ovarian Pregnancy Ovarian Pregnancy An ectopic pregnancy of unknown etiology that occurs in the ovary instead of the uterine corpus. It may result in severe intra-abdominal bleeding. C34945 Ectopic Pregnancy C90259 NICHD Pediatric Terminology C66849 Ovulation Ovulation Release of Egg The discharge of a secondary oocyte from a vesicular follicle of the ovary. C21173 Reproductive Process C90259 NICHD Pediatric Terminology C2283 Oxytocin Oxytocin Oxytocin (125 aa, ~13kDa) is encoded by the human OXT gene. This protein plays a role in smooth muscle contraction in both the mammary gland and uterus. Oxytocin also is involved in maternal-newborn bonding, cognition and many other psychological and physiological processes. C13236 Biological Substance C90259 NICHD Pediatric Terminology C3303 Pain Pain The sensation of discomfort, distress, or agony, resulting from the stimulation of specialized nerve endings. C4876 Symptom C90259 NICHD Pediatric Terminology C50685 Pallor Pallor An unusual or extreme paleness, state of decreased skin coloration. C4876 Symptom C90259 NICHD Pediatric Terminology C97194 Panic Disorder with Agoraphobia Panic Disorder with Agoraphobia A disorder in which an individual experiences recurrent, unexpected panic attacks and persistent concern about having additional panic attacks. Agoraphobia is a component of this disorder. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology C97193 Panic Disorder without Agoraphobia Panic Disorder without Agoraphobia A disorder in which an individual experiences recurrent, unexpected panic attacks and persistent concern about having additional panic attacks. Agoraphobia is not a component of this disorder. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology C17348 Papanicolaou Smear Procedure Pap Smear A sample of secretions and superficial cells of the body of uterus, cervix, and ovaries; examined with a microscope to detect any abnormal cells. C15843 Preventive Intervention C90259 NICHD Pediatric Terminology C27864 Parasitic Infection Parasitic Disease A successful invasion of a host by an organism that uses the host for food and shelter. C26726 Infectious Disease C90259 NICHD Pediatric Terminology C38291 Parenteral Route of Administration Parenteral Route of Administration Administration of a substance by some means other than through the gastrointestinal tract: usually through injection, infusion, or implantation. Predominantly, the drug action is systemic, but in some cases, it is confined to local area. C38114 Route of Administration C90259 NICHD Pediatric Terminology C81275 Pass Pass One of two possible results of a pass/fail assessment; when the result satisfies a condition. C25180 Indicator C90259 NICHD Pediatric Terminology C92840 Passing of Mucus Plug Passing of Mucus Plug A discharge of the mucus plug from the cervical os during cervical dilation in preparation for the labor and delivery of the baby. C92819 Intrapartum Process C90259 NICHD Pediatric Terminology C89328 Non-Neoplastic Pediatric Disorder Pediatric Disease or Disorder A non-neoplastic disease that typically manifests prior to adulthood. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C90341 Pediatric Intervention or Procedure Pediatric Intervention or Procedure A diagnostic or therapeutic course of action usually performed on patients under the age of 18. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology C92841 Perinatal Death Perinatal Death The death of an infant before birth after 28 weeks of gestation or shortly after birth. C90491 Pregnancy Outcome C90259 NICHD Pediatric Terminology C92842 Persistent Fetal Bradycardia Persistent Fetal Bradycardia A decrease in the fetal heart beat rate below 110 per minute or below the normal baseline value expected for the particular fetal age for a period of more than 10 minutes. C92782 Fetal Bradycardia C90259 NICHD Pediatric Terminology C92843 Persistent Fetal Tachycardia Persistent Fetal Tachycardia An increase in the fetal heart rate above the expected normal baseline values for an extended period. C92796 Fetal Tachycardia C90259 NICHD Pediatric Terminology C25190 Person Person A human being. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C25191 Person Name Person Name A word or group of words indicating the identity of a person usually consisting of a first (personal) name and a last (family) name with an optional middle name. In some cultural traditions the family name comes first. C90492 Personal Information C90259 NICHD Pediatric Terminology C90492 Personal Information Personal Information Data, facts or figures about an individual; the set of relevant items would depend on the use case. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C18772 Personal Medical History Personal Medical History A record of a patient's background regarding health and the occurrence of disease events of the individual. In addition, personal medical history may be a variable in epidemiologic studies. C90492 Personal Information C90259 NICHD Pediatric Terminology C97179 Pervasive Developmental Disorder Pervasive Developmental Disorder A category of developmental disorders characterized by impaired communication and socialization skills. The impairments are incongruent with the individual's developmental level or mental age. These disorders can be associated with general medical or genetic conditions. C96412 Brain Development Abnormality C89338 Neurodevelopmental Disorder C90259 NICHD Pediatric Terminology C1909 Pharmacologic Substance Pharmacologic Substance An active natural, synthetic or semi-synthetic ingredient including endogenous body substance that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the human body, but does not include intermediates used in the synthesis of such ingredient (21 CFR 314.3(b)). C45306 Substance C90259 NICHD Pediatric Terminology C81280 Phenylalanine Measurement Phenylalanine Measurement The measurement of the amount of phenylalanine in a biologic specimen. C25294 Laboratory Procedure C90259 NICHD Pediatric Terminology C81281 Phenylalanine to Tyrosine Ratio Measurement Phenylalanine to Tyrosine Ratio Measurement The determination of the ratio of phenylalanine compared to tyrosine present in a sample. The measurement may be expressed as a ratio or percentage. C25294 Laboratory Procedure C90259 NICHD Pediatric Terminology C81315 Phenylketonuria Phenylketonuria A disorder characterized by the body's inability to break down and utilize the essential amino acid phenylalanine. C34816 Congenital Metabolic Disorder C90259 NICHD Pediatric Terminology C20989 Physical Examination Physical Examination A systemic evaluation of the body and it's functions using visual inspection, palpation, percussion and auscultation. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment. C18020 Diagnostic Procedure C90259 NICHD Pediatric Terminology C89518 Physical Maturity Assessment Physical Maturity Assessment An examination of the following neonatal attributes: 1) skin texture; 2) lanugo; 3) plantar creases; 4) breast; 5) eyes and ears; 6) genitals, male; and 7) genitals, female. It is a subscore of the Dubowitz/Ballard Examination for Gestational Age. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C81316 Physical Symmetry Physical Symmetry A physical attribute of visual balance and proportion between opposing structures. C25447 Characteristic C90259 NICHD Pediatric Terminology C92844 Physiologic Lightening Physiologic Lightening A physical feeling of being able to breathe better during late trimester of pregnancy when the baby starts to descend lower into the pelvic cavity. C92819 Intrapartum Process C90259 NICHD Pediatric Terminology C41148 Placement Placement Position or arrangement, as of the teeth; the state of being placed or arranged, as the assignment of a person to a appropriate clinical study. C92722 Qualitative Concept C90259 NICHD Pediatric Terminology C26858 Placenta Previa Placenta Previa A condition in which the placenta is implanted in the lower part of the uterus. --2003 C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C26685 Premature Separation of Placenta Placental Abruption The separation of the placenta from the maternal uterine attachment when it occurs after the twentieth week of the pregnancy. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C92854 Postpartum Placental Separation Placental Separation A process in childbirth in which the placenta separates from its uterine lining, after the delivery of the baby. C92935 Postpartum Process C90259 NICHD Pediatric Terminology C97120 Pneumococcal 10-valent Conjugate Vaccine Pneumococcal 10-valent Conjugate Vaccine An active immunizing vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. It is indicated for disease caused by serotypes 1, 5, 4, 6B, 7, 9V, 14, 18C, 19F, and 23F. C97123 Pneumococcal Conjugate Vaccine C90259 NICHD Pediatric Terminology C97121 Pneumococcal 13-valent Conjugate Vaccine Pneumococcal 13-valent Conjugate Vaccine An active immunizing vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. It is indicated for disease caused by serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F. It can also be used to prevent against otitis media by serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F. C97123 Pneumococcal Conjugate Vaccine C90259 NICHD Pediatric Terminology C1643 Pneumococcal Polyvalent Vaccine Pneumococcal 23-valent Polysaccharide Vaccine An polyvalent vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. Pneumococcal polyvalent vaccine contains highly purified capsular antigens from the 23 most prevalent or invasive pneumococcal types of Streptococcus pneumoniae to ensure cross-protection. Following vaccination, protective capsular type-specific antibody levels typically develop by the third week; serotype-specific antibody levels generally decline after 5-10 years. C97125 Polysaccharide Vaccine C90259 NICHD Pediatric Terminology C38141 Pneumococcal 7-Valent Conjugate Vaccine Pneumococcal 7-Valent Conjugate Vaccine An active immunizing agent used to prevent infection by the bacterium Streptococcus pneumoniae. Pneumococcal 7-valent conjugate vaccine consists of a solution of saccharides of the capsular antigens of Streptococcus serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F individually conjugated to diphtheria CRM 197 protein. C97123 Pneumococcal Conjugate Vaccine C90259 NICHD Pediatric Terminology C97123 Pneumococcal Conjugate Vaccine Pneumococcal Conjugate Vaccine An active immunizing vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. It consists of a solution of saccharides of the capsular antigens of Streptococcus serotypes individually conjugated to proteins. C1455 Conjugate Vaccine C90259 NICHD Pediatric Terminology C3333 Pneumonia Pneumonia An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, due to infections (viruses, fungi, mycoplasma, or bacteria), treatment (e.g. radiation), or exposure (inhalation) to chemicals. Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness. C26871 Respiratory System Disorder C90259 NICHD Pediatric Terminology C81297 Point in Time Test Given Point in Time Test Given The hour, minute, and/or second that an examination was administered. C25207 Time C90259 NICHD Pediatric Terminology C96409 Polio Vaccination Polio Vaccination The administration a series of either live or inactivated poliovirus for the prophylaxis of poliomyelitis. C15258 Immunization C90259 NICHD Pediatric Terminology C35550 Acute Poliomyelitis Poliomyelitis Polio An acute infectious disorder that affects the nervous system. It is caused by the poliovirus. The virus spreads by direct contact, and can be prevented by prophylaxis with the polio vaccine. C96411 Childhood Viral Disease C90259 NICHD Pediatric Terminology C14259 Poliovirus Poliovirus An enterovirus comprised of an single-stranded positive sense RNA genome and a protein capsid. This virus is the human pathogen that causes poliomyelitis. C14283 Virus C90259 NICHD Pediatric Terminology C92847 Polycystic Ovary Syndrome Polycystic Ovary Syndrome A disorder that manifests as multiple cysts on the ovaries. It results in hormonal imbalances and leads to irregular and abnormal menstrual periods, excess growth of hair, acne eruptions and obesity. C3009 Endocrine System Disorder C90259 NICHD Pediatric Terminology C87110 Polydactyly Polydactyly A congenital abnormality characterized by more than 5 digits on a hand or foot. C89337 Congenital Abnormality of the Musculoskeletal System C90259 NICHD Pediatric Terminology C92848 Polyhydramnios Polyhydramnios An excess quantity of amniotic fluid in the amniotic sac as compared to normal values. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C97125 Polysaccharide Vaccine Polysaccharide Vaccine A category of vaccines that use the extracted and purified outer polysaccharide coat of the particular bacteria. C923 Vaccine C90259 NICHD Pediatric Terminology C2848 Polyvalent Vaccine Polyvalent Vaccine A vaccine designed to elicit an immune response either to more than one infectious agent or to several different antigenic determinants of a single agent. C923 Vaccine C90259 NICHD Pediatric Terminology C87111 Poor Feeding Poor Feeding Occurs either when an infant shows no interest in feeding or when there is an inability to take in adequate nutrition. Poor feeding is a nonspecific symptom of many disorders, including neurological, genetic, structural, metabolic, and infectious diseases. C4876 Symptom C90259 NICHD Pediatric Terminology C89519 Popliteal Angle Measurement Popliteal Angle Measurement An examination whereby the patient is placed supine, the hip is flexed 90 degrees, and the knee is extended until firm resistance is met. The popliteal angle is the angle from the tibia to the femur. This measurement is used to assess hamstring contracture in children with cerebral palsy. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C92849 Positive Pregnancy Test Positive Pregnancy Test A test result indicating the presence of hormones (HCG) in the blood or urine of a woman that confirm pregnancy . C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C25621 Postal Code Postal Code Any system designed to expedite the sorting and delivery of mail by assigning a series of alphanumeric codes to each delivery area. Also used to refer to any individual delivery area code. C16495 Demographics C90259 NICHD Pediatric Terminology C92850 Posterior Occiput Presentation Posterior Occiput A fetal position during delivery in which the head of the fetus is facing the mother's abdomen. C92926 Fetal Position C90259 NICHD Pediatric Terminology C90338 Maternal Postnatal Stage Postnatal Stage The stage in the life of a mother after she has given birth. C90337 Maternal Life Stage C90259 NICHD Pediatric Terminology C92851 Postpartum Postpartum The period of time immediately after labor and delivery. C92858 Pregnancy Time Period C90259 NICHD Pediatric Terminology C92852 Postpartum Depression Postpartum Depression A type of clinical depression that occurs after childbirth. C2982 Depression C90259 NICHD Pediatric Terminology C92853 Postpartum Hemorrhage Postpartum Hemorrhage Hemorrhage defined as a blood loss in excess of 500 mL after vaginal delivery or more than 1000 mL after a cesarean delivery. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C92935 Postpartum Process Postpartum Process The recovery and readjustment process in a mother after pregnancy and delivery. C92934 Labor and Delivery Process C90259 NICHD Pediatric Terminology C92936 Postpartum Recovery Post-Partum Recovery The healing and recuperation of the mother including physiological readjustment after pregnancy and delivery of the baby. C92935 Postpartum Process C90259 NICHD Pediatric Terminology C3389 Post-Traumatic Stress Disorder Post-Traumatic Stress Disorder An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by intrusive recurring thoughts or images of the traumatic event; avoidance of anything associated with the event; a state of hyperarousal and diminished emotional responsiveness. These symptoms are present for at least one month and the disorder is usually long-term. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology C48531 Pound Pound The traditional unit of mass. By international agreement, one avoirdupois pound is equal to exactly 0.453 592 37 kilogram, 16 ounces, or 1.215 28 troy pounds. C25709 Unit of Measure C90259 NICHD Pediatric Terminology C90340 Maternal Preconception Stage Preconception Stage The stage in the life of a female during which she is attempting to get pregnant. C90337 Maternal Life Stage C90259 NICHD Pediatric Terminology C85021 Preeclampsia Preeclampsia A pregnancy-related disorder characterized by an increase in the blood pressure after the twentieth week of gestation, and by the presence of proteinuria. It may appear up to six weeks post-partum. It may lead to eclampsia with development of tonic-clonic seizures. C4371 Pregnancy Induced Hypertension C90259 NICHD Pediatric Terminology C25742 Pregnancy Pregnancy The state or condition of having a developing embryo or fetus in the body (uterus), after union of an ovum and spermatozoon, during the period from conception to birth. C21173 Reproductive Process C90259 NICHD Pediatric Terminology C91825 Pappalysin-1 Pregnancy Associated Plasma Protein A Pappalysin-1 (1627 aa, ~181 kDa) is encoded by the human PAPPA gene. This protein is involved in the modulation of proteolysis. C92745 Blood Test for Protein Level C90259 NICHD Pediatric Terminology C34941 Pregnancy Complication Pregnancy Complication The co-occurrence of pregnancy and a disease. The disease may precede or follow conception and it may or may not have a deleterious effect on the pregnant woman or fetus. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C92720 Pregnancy Finding Pregnancy Finding Symptoms, signs, diagnostic examinations or a test results in a pregnant mother. C36284 Reproductive System Finding C90259 NICHD Pediatric Terminology C4371 Pregnancy Associated Hypertension Pregnancy Induced Hypertension The most common complication of pregnancy. It may appear as chronic hypertension or preeclampsia. It may cause brain hemorrhage, pulmonary edema, abruptio placentae, gestational diabetes mellitus, renal failure, premature delivery and fetal growth abnormalities. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C90491 Pregnancy Outcome Pregnancy Outcome Findings observed at the end of a pregnancy. C36284 Reproductive System Finding C90259 NICHD Pediatric Terminology C92949 Pregnancy Test Pregnancy Test Any examination performed to assess if a female is gravid. C18020 Diagnostic Procedure C90259 NICHD Pediatric Terminology C92858 Pregnancy Time Period Pregnancy Time Period The duration of pregnancy from conception to childbirth. C21514 Temporal Qualifier C90259 NICHD Pediatric Terminology C50917 Premature Labor Premature Labor Ouster of a viable infant before the normal end of gestation, commonly defined as interruption of pregnancy between the twentieth-thirty seventh completed weeks after the onset of the last menstrual cycle. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C87113 Premature Rupture of Membrane Premature Rupture of Membranes PROM The condition when a patient who is beyond 37 weeks gestation presents with rupture of membranes prior to the onset of labor. Rupture of membranes is diagnosed by speculum vaginal examination of the cervix and vaginal cavity, which will show pooling of fluid in the vagina or leakage of fluid from the cervix. Preterm PROM (known as PPROM) refers to a patient who has not yet reached 37 weeks gestation and presents with rupture of membranes. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C81318 Prenatal Prenatal The time period after impregnation and before birth. C92858 Pregnancy Time Period C90259 NICHD Pediatric Terminology C90339 Maternal Prenatal Stage Prenatal Stage The stage in the life of a mother during which she is pregnant. C90337 Maternal Life Stage C90259 NICHD Pediatric Terminology C92860 Prenatal Vitamin Prenatal Vitamins A vitamin enriched supplement containing higher doses for specific nutrients such as folic acid, intended for women before, during and after pregnancy and also during their lactating phase. C45306 Substance C90259 NICHD Pediatric Terminology C92861 Preterm Birth Preterm Birth The birth of an infant of less than 37 weeks for the gestational age. C90491 Pregnancy Outcome C90259 NICHD Pediatric Terminology C89888 Preterm Neonatal Stage Preterm Neonatal Stage The period at birth when a newborn is born prior to the full gestational period. A human life stage that begins at birth prior to thirty-seven weeks of full gestation (full term) and continues until twenty-seven complete days after birth. C89345 Child Life Stage C90259 NICHD Pediatric Terminology C49642 Preterm Newborn Infant Preterm Newborn Infant An infant born prior to completion of the normal gestation period. C16731 Newborn C90259 NICHD Pediatric Terminology C92862 Preterm Premature Rupture of Membrane Preterm Premature Rupture of Membrane PPROM An early rupture of the amniotic membranes during pregnancy and one that precedes 37 weeks of gestation. C87113 Premature Rupture of Membranes C90259 NICHD Pediatric Terminology C15843 Preventive Intervention Preventive Intervention Therapeutic, nutritional, environmental, social and or behavioral interventions at the societal, community, organizational or individual levels to reduce, modify or stop the course of a disease. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology C778 Prolactin Prolactin Human prolactin (227 aa, 26 kDa precursor) is encoded by the human prolactin (PIT1) gene. This secreted lactogenic glycoprotein is expressed in both anterior pituitary lactotropes and the decidual endometrium. It acts primarily on the mammary gland and, in synergy with estrogen, induces progesterone release by corpus luteum cells to render the uterine mucosa suitable for implantation. C13236 Biological Substance C90259 NICHD Pediatric Terminology C92863 Prolonged Fetal Heart Rate Acceleration Prolonged Acceleration An abrupt and extended increase in the fetal heart rate during labor contractions. C92788 Fetal Heart Rate Acceleration C90259 NICHD Pediatric Terminology C92864 Prolonged Fetal Heart Rate Deceleration Prolonged Deceleration An extended decrease in the fetal heart rate compared to the normal baseline values. C92789 Fetal Heart Rate Deceleration C90259 NICHD Pediatric Terminology C20189 Property or Attribute Property or Attribute A distinguishing quality or prominent aspect of a person, object, action, process, or substance. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C87114 Proptosis Proptosis Abnormal protrusion of one or both eyes from the socket; causes include hyperthyroidism (particularly Graves disease); bleeding behind the eye; infection, inflammation, or tumors of the orbit; and vascular disorders. C35126 Vision Disorder C90259 NICHD Pediatric Terminology C2893 Psychiatric Disorder Psychiatric Disorder A disorder characterized by behavioral and/or psychological abnormalities, often accompanied by physical symptoms. The symptoms may cause clinically significant distress or impairment in social and occupational areas of functioning. Representative examples include anxiety disorders, cognitive disorders, mood disorders and schizophrenia. C96413 Brain Disorder C90259 NICHD Pediatric Terminology C87130 Pterygium Colli Pterygium Colli A congenital, usually bilateral, thick web-like fold of skin that extends from the acromion to the mastoid process. This deformity is associated with Turner Syndrome and Noonan Syndrome. C97174 Congenital Abnormality of the Skin C90259 NICHD Pediatric Terminology C49676 Pulse Rate Pulse Rate The rate of the pulse as observed in an artery, expressed as beats per minute. It can be measured at several anatomical sites, including the wrist, neck, temple, groin, behind the knees, or on top of the foot. C81274 Numeric Value C90259 NICHD Pediatric Terminology C87108 Pupils Equal Round and Reactive to Light and Accommodation Result Pupils Equal Round and Reactive to Light and Accommodation Result While performing an assessment of the eyes, the examiner notes whether the pupils are equal and round, reactive to light, and have the ability to accommodate. If all findings are normal, the abbreviation PERRLA is noted in the examiner's account of the physical examination. C77140 Clinical Test Result C90259 NICHD Pediatric Terminology C87107 Pupils Equal Round and Reactive to Light Result Pupils Equal Round and Reactive to Light Result While performing an assessment of the eyes, the examiner notes whether the pupils are equal, round, and reactive to light. If all findings are normal, the abbreviation PERRL is noted in the examiner's account of the physical examination. C77140 Clinical Test Result C90259 NICHD Pediatric Terminology C34965 Pyelonephritis Pyelonephritis An acute or chronic inflammatory process affecting the kidney. It is caused by bacteria and in most cases it is the result of a urinary tract infection. Signs and symptoms include fever, chills, flank pain, painful and frequent urination, cloudy or bloody urine, and confusion. C2890 Bacterial Disease C90259 NICHD Pediatric Terminology C92865 Quad Screen Quad Screen A screening measurement in which the maternal blood levels of alpha-fetoprotein, unconjugated estriol, human chorionic gonadotrophin and Inhibin A are calculated. These are then evaluated in relation to the mother's age, weight and fetal gestational age. C92803 Screening for Genetic Defect C90259 NICHD Pediatric Terminology C92722 Qualitative Qualitative Concept A measurement expressed in words rather than numbers. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C70766 Quantitative Quantitative Concept Capable of being estimated or expressed with numeric values. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C17049 Race Race An arbitrary classification of a taxonomic group that is a division of a species. It usually arises as a consequence of geographical isolation within a species and is characterized by shared heredity, physical attributes and behavior, and in the case of humans, by common history, nationality, or geographic distribution. C16495 Demographics C90259 NICHD Pediatric Terminology C38013 Range Range The difference between the lowest and highest numerical values; the limits or scale of variation. C70766 Quantitative Concept C90259 NICHD Pediatric Terminology C29091 Hepatitis B Vaccine Recombinant Hepatitis B Vaccine A non-infectious mixture containing recombinant hepatitis B surface antigen (HBsAg) in a liquid vehicle. Immunization with the hepatitis B vaccine induces the formation of specific anti-hepatitis B antibodies and an active immunity against hepatitis B infection. C1572 Recombinant Viral Vaccine C90259 NICHD Pediatric Terminology C1951 Human Papilloma Virus Vaccine Recombinant Human Papilloma Virus Vaccine A recombinant vaccine of different types of HPV proteins which are well-conserved within types with a significant inter-type variation. C1572 Recombinant Viral Vaccine C90259 NICHD Pediatric Terminology C1572 Recombinant Viral Vaccine Recombinant Viral Vaccine A vaccine produced from genetically engineered viral vector by introduction of foreign genetic materials to activate immune response in a host. C923 Vaccine C90259 NICHD Pediatric Terminology C12390 Rectum Rectum The terminal portion of the gastrointestinal tract, extending from the rectosigmoid junction to the anal canal. C32221 Body Part C90259 NICHD Pediatric Terminology C92866 Recurrent Fetal Heart Rate Deceleration Recurrent Deceleration A frequently repeated decrease in the fetal heart rate that occurs in conjunction with a uterine contraction; this happens with the majority of heartbeats. C92789 Fetal Heart Rate Deceleration C90259 NICHD Pediatric Terminology C81283 Red Reflex Vision Test Red Reflex Vision Test An optic examination in which an ophthalmoscope or retinoscope is placed approximately 30cm from the eye to visualize whether a reddish hue is reflected from the retina. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C4077 Redness Redness Coloration of the skin; sign of inflammation C4876 Symptom C90259 NICHD Pediatric Terminology C52582 Referral Referral Sending a patient from one practitioner to another for health care services. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology C81319 Reflex Irritability Score Reflex Irritability Score A component of the APGAR score, it is the numerical value assigned to the neonate's response to stimuli, such as a mild pinch. 0 = no reaction; 1 = grimace; 2 = grimace with a cough, sneeze, or vigorous cry. C81274 Numeric Value C90259 NICHD Pediatric Terminology C64381 Regional Anesthesia Procedure Regional Anesthesia Procedure The administration of pharmaceutical agents intended to produce loss of sensation in a particular anatomical region. C15181 Anesthesia Procedure C90259 NICHD Pediatric Terminology C92867 Regular Uterine Contraction Regular Contraction A consistent rhythmic pattern of uterine muscle tightening that occurs at regular intervals for the same duration of time. C92904 Uterine Contraction C90259 NICHD Pediatric Terminology C92868 Regularity of Uterine Contraction Regularity of Uterine Contraction The nature and pattern of occurrence for the uterine contractions during labor. C70766 Quantitative Concept C90259 NICHD Pediatric Terminology C50726 Regurgitation Regurgitation Flow in the opposite direction from normal, as the casting up of undigested food or gas from the stomach, or the backward flowing of blood into the heart, or between the chambers of the heart when a valve is incompetent. C4876 Symptom C90259 NICHD Pediatric Terminology C21173 Reproductive Process Reproductive Process A Reproductive System Process involves a function of cellular, cell, or tissue components of the organ system involved in generation of offspring that includes the ovaries, fallopian tubes, uterus, cervix, and vagina in women or the prostate, testes, and penis in men. C19988 Organismal Process C90259 NICHD Pediatric Terminology C4875 Reproductive System Disorder Reproductive System Disorder A non-neoplastic or neoplastic disorder that affects the male or female genital system. Representative examples of non-neoplastic disorders include infection, testicular torsion, endometriosis, and adenomyosis. Representative examples of neoplastic disorders include germ cell tumors, carcinoma, lymphoma, and sarcoma. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C36284 Reproductive System Finding Reproductive System Finding Symptoms, physical examination results, and/or laboratory test results related to the reproductive system. C70856 Observational Result C90259 NICHD Pediatric Terminology C15429 Research Activity Research Activity Systematic investigation into a subject in order to discover facts, establish or revise a theory, or develop a plan of action based on the facts discovered. C16205 Healthcare Activity C90259 NICHD Pediatric Terminology C81284 Residential Telephone Number Residential Telephone Number The sequence of numbers or characters, that when dialed, connects to a particular residential telephone. C40978 Telephone Number C90259 NICHD Pediatric Terminology C27561 Respiratory Distress Syndrome Respiratory Distress Syndrome A group of conditions characterized by failure of normal respiration caused by lack of lung surfactant. C26871 Respiratory System Disorder C90259 NICHD Pediatric Terminology C49678 Respiratory Rate Respiratory Rate The rate of breathing (inhalation and exhalation) measured within in a unit time, usually expressed as breaths per minute. C81274 Numeric Value C90259 NICHD Pediatric Terminology C26871 Respiratory Disorder Respiratory System Disorder A non-neoplastic or neoplastic disorder that affects the tracheobronchial tree and/or the lung parenchyma. Representative examples include infections, carcinomas, and lymphomas. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C34982 Retinopathy of Prematurity Retinopathy of Prematurity A bilateral retinopathy characterized by neovascularization, scarring, retinal detachment, and eventually blindness. It may be mild or severe. It occurs in babies born prematurely. Causes include oxygen toxicity and hypoxia. C97172 Congenital Abnormality of the Nervous System C90259 NICHD Pediatric Terminology C75488 Rett Syndrome Rett Syndrome A progressive neurologic disorder caused by mutations in the MECP2 gene on chromosome X. It almost exclusively affects girls. It is characterized by language and learning difficulties, poor communication skills, and repetitive hand motions. Other signs and symptoms include microcephaly, scoliosis, breathing abnormalities, and sleep disturbances. C97179 Pervasive Developmental Disorder C90259 NICHD Pediatric Terminology C92948 Rh Factor Measurement Rh factor Measurement An immunology test to measure for the presence of the Rh factor antigen in blood. C47868 Blood Test C90259 NICHD Pediatric Terminology C92947 Rh Immune Globulin Administration Rh Immune Globulin Administration Rho(D) Immune Globulin Administration The administration of Rh Immune Globulin to a pregnant mother to ameliorate the effects of conflicting Rh factors during pregnancy. C15843 Preventive Intervention C90259 NICHD Pediatric Terminology C84504 Rh Incompatibility Rh Incompatibility A complication during pregnancy; it occurs when the mother is Rh-negative and the infant is Rh-positive. The mother's body develops antibodies against the fetal red blood cells leading to their destruction. This complication generally does not affect first-born Rh-positive babies. Rh-positive newborn babies from subsequent pregnancies develop complications of Rh incompatibility which include hemolysis, jaundice, enlarged liver and spleen, petechiae, hypotonia, neurologic damage, and heart problems. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C87116 Rhonchi Rhonchi An abnormal sound similar to snoring heard on auscultation of the bronchial airways, suggesting a partial obstruction due to thick secretions, a muscular spasm, or a neoplasm. C4876 Symptom C90259 NICHD Pediatric Terminology C81285 Right Ear Right Ear The organ of hearing located on the right side of the head. C32221 Body Part C90259 NICHD Pediatric Terminology C92871 Right Occiput Anterior Presentation Right Occiput Anterior ROA A fetal position during delivery in which the fetus is in the birth canal and the back of the head is oriented towards the maternal right thigh region. C92732 Anterior Occiput C90259 NICHD Pediatric Terminology C17103 Risk Factor Risk Factor Any aspect of an individual's life, behavior, an environmental exposure, or an inborn or inherited characteristic that increases the likelihood of a disease, condition or injury. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C90498 Risk Factor Assessment Risk Factor Assessment A systematic gathering of information regarding the variables associated with an individual's increased risk of disease or infection. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology C81320 Rooting Reflex Rooting Reflex An involuntary, primal response in the neonate to search for the nipple when the cheek is touched. C81181 Infant Reflex C90259 NICHD Pediatric Terminology C77199 Rotavirus Rotavirus A genus of double stranded RNA viruses that carry 11 unique double helix molecules of RNA that encode one or two proteins each. The RNA is surrounded by a three-layered icosahedral protein capsid. Viral particles are up to 76.5 nm in diameter and are not enveloped. C14283 Virus C90259 NICHD Pediatric Terminology C96394 Rotavirus Vaccine Rotavirus Vaccine A viral vaccine that prevents against rotavirus infection, the leading cause of severe acute gastroenteritis. C1920 Attenuated Live Virus Vaccine C90259 NICHD Pediatric Terminology C38114 Route of Administration Route of Administration Designation of the part of the body through which or into which, or the way in which, the medicinal product is intended to be introduced. In some cases a medicinal product can be intended for more than one route and/or method of administration. C16847 Technique C90259 NICHD Pediatric Terminology C69284 R-R Interval R-R Wave Period The time measurement between the R wave (ventricular depolarization) of successive heartbeats as measured in milliseconds. C92790 Fetal Heart Rate Variability C90259 NICHD Pediatric Terminology C92872 Rubella Immunization Rubella Immunization The administration of a live attenuated viral vaccine to prevent rubella infection. C15258 Immunization C90259 NICHD Pediatric Terminology C85051 Rubella Infection Rubella Infection German Measles A viral infection caused by the rubella virus. It is initially manifested with flu-like symptoms that last one or two days, followed by the development of a characteristic red rash which lasts from one to five days. The rash first appears in the neck and face. It subsequently spreads to the rest of the body. C3439 Viral Disease C90259 NICHD Pediatric Terminology C92874 Rupture of Membrane Rupture of Membrane amniorrhexis|breaking water Breaking or tearing of the amniotic membranes during childbirth leading to the leakage of amniotic fluid and the progression of labor. C92819 Intrapartum Process C90259 NICHD Pediatric Terminology C87118 Sacral Dimple Sacral Dimple A sacral dimple, or pilonidal dimple, is a small hollow area or sinus present at birth and located just above the crease of the buttocks. In most cases, pilonidal dimples are benign and may just be accompanied by increased hair growth in the area. C97174 Congenital Abnormality of the Skin C90259 NICHD Pediatric Terminology C81288 S-Beta Thalassemia S-Beta Thalassemia A disorder characterized by the body's inability to synthesize beta-globin chains, leading to the formation of abnormal hemoglobin and anemia. This inherited autosomal recessive blood disorder is caused by germline mutation of the HBB gene. C35729 Congenital Abnormality of the Circulatory System C90259 NICHD Pediatric Terminology C89521 Scarf Sign Scarf Sign When testing the newborn infant for neuromuscular maturity, the "scarf sign" test is carried out by drawing the newborn's arm across the chest to the opposite shoulder until resistance is felt. In term infants, the elbow should not cross the midline of the chest. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C92846 Placental Schultze Mechanism Schultze Mechanism The separation of the placenta from the uterine wall during labor; it begins at the placental center and leads to an expulsion of the placenta after delivery of the baby. C92766 Delivery of Placenta C90259 NICHD Pediatric Terminology C78603 Scoliosis Scoliosis A congenital or acquired spine deformity characterized by lateral curvature of the spine. C27574 Musculoskeletal System Disorder C90259 NICHD Pediatric Terminology C92916 Varicella Zoster Virus Screening Screening for Chickenpox A test to determine if an individual has antibodies to the varicella zoster virus. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C92803 Genetic Screening Screening for Genetic Defect Testing to determine if there is a predisposition or indication of a possible genetic or a chromosomal abnormality. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C92873 Rubella Screening Screening for Rubella A test during pregnancy to determine maternal exposure to the rubella virus that could lead to pregnancy complications or congenital rubella syndrome in the newborn. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C92721 Pregnancy Related Screening Screening or Clinical Tests during Pregnancy A group of tests performed during pregnancy to assess fetal health and to detect for genetic abnormalities and various disorders. C15843 Preventive Intervention C90259 NICHD Pediatric Terminology C92875 Second Stage of Labor Second Stage of Labor Birthing Stage A stage during labor and childbirth when the cervix is effaced totally and remains dilated until the birth of the baby. C92723 Stages of Labor C90259 NICHD Pediatric Terminology C92876 Second Trimester Second Trimester The period of gestation that ranges from the 13th to the 27th week of pregnancy. C69121 Trimester C90259 NICHD Pediatric Terminology C2962 Seizure Seizure Sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin. C4876 Symptom C90259 NICHD Pediatric Terminology C92569 Selective Mutism Selective Mutism A persistent failure to speak in certain social situations (i.e., school) where speaking is expected, despite speaking in other situations. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology C26739 Sensorineural Deafness Sensorineural Hearing Loss Hearing loss caused by a problem in the inner ear or auditory nerve. A sensorineural loss often affects a person's ability to hear some frequencies more than others. This means that sounds may be appear distorted, even with the use of a hearing aid. Sensorineural losses can range from mild to profound. C35731 Hearing Loss C90259 NICHD Pediatric Terminology C63711 Neurosensory Disorder Sensory Disorder An interruption or alteration in the sensory activity or functions of the nervous system. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C35014 Separation Anxiety Disorder Separation Anxiety Disorder An anxiety disorder characterized by recurrent excessive distress due to fear of separation from the home or from major attachment figures; the distress is developmentally inappropriate and causes impairment in social, academic, or other areas of functioning. C92190 Childhood Mental Disorder C90259 NICHD Pediatric Terminology C3364 Septicemia Sepsis The presence of pathogenic microorganisms in the blood stream causing a rapidly progressing systemic reaction that may lead to shock. Symptoms include fever, chills, tachycardia, and increased respiratory rate. It is a medical emergency that requires urgent medical attention. C2890 Bacterial Disease C90259 NICHD Pediatric Terminology C28421 Sex Sex The assemblage of physical properties or qualities by which male is distinguished from female; the physical difference between male and female; the distinguishing peculiarity of male or female. C25447 Characteristic C90259 NICHD Pediatric Terminology C92877 Sexual Abstinence Sexual Abstinence Prevention of contraception by not engaging in sexual intercourse. C37932 Contraception C90259 NICHD Pediatric Terminology C92878 Sexually Transmitted Disease Screening Sexually Transmitted Disease Screening A test to detect the presence of a sexually transmissible disease such as HIV, chlamydia, syphilis, gonorrhea, hepatitis B or hepatitis C. C15843 Preventive Intervention C90259 NICHD Pediatric Terminology C92879 Short-Term Fetal Heart Rate Variability Short-Term Variability A non-sustained irregular fetal heart rate in comparison to normal baseline values. C92790 Fetal Heart Rate Variability C90259 NICHD Pediatric Terminology C25203 Shoulder Shoulder The region of the body between the neck and the upper arm. C32221 Body Part C90259 NICHD Pediatric Terminology C81290 Shoulder Dystocia Shoulder Dystocia Abnormal labor or childbirth due to fetal shoulder obstruction in the vaginal canal. C81236 Birth Complication C90259 NICHD Pediatric Terminology C92880 Shoulder Presentation Shoulder Presentation A fetal position during delivery in which the shoulder descends into the birth canal first. C92793 Malpresentation of Fetus C90259 NICHD Pediatric Terminology C81291 Sick Newborn Sick Newborn A neonate that is unwell. C16731 Newborn C90259 NICHD Pediatric Terminology C34383 Sickle Cell Disease Sickle Cell Disease A blood disorder characterized by the appearance of sickle-shaped red blood cells and anemia. C35729 Congenital Abnormality of the Circulatory System C90259 NICHD Pediatric Terminology C92881 Signs of Impending Birth Signs of Impending Birth The indicating characteristics in a pregnant mother who is in the process of labor and delivery of a fetus; common signs and symptoms include nesting, anxiety, excitement, loss of mucous plug, increased urinary frequency and loose bowel movements. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C92882 Sinciput Presentation Sinciput A fetal position during delivery in which the frontal part of the skull including forehead and the top of the head is first to descend into the birth canal. C92926 Fetal Position C90259 NICHD Pediatric Terminology C87120 Single Palmar Crease Single Palmar Crease A single transverse palmar crease is found in 5% of newborns and is frequently inherited as a familial trait. However, single palmar creases can be associated with Down's syndrome and other genetic disorders, or with fetal alcohol syndrome. C97174 Congenital Abnormality of the Skin C90259 NICHD Pediatric Terminology C35024 Sinusitis Sinus Infection An acute or chronic infectious process affecting the mucous membranes of the paranasal sinuses. C26726 Infectious Disease C26871 Respiratory System Disorder C90259 NICHD Pediatric Terminology C87121 Situs Inversus Situs Inversus A congenital condition in which there is complete right-to-left reversal of the position of the major thoracic and abdominal organs (that is, they are arranged in a mirror image of the normal positioning). C97151 Systemic Congenital Disorder C90259 NICHD Pediatric Terminology C92856 Pregnancy Related Skin Change Skin Changes Alterations in the skin's appearance during pregnancy due to hormonal level changes. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C81321 Skin Color Score Skin Color Score A component of the APGAR score, it is the numerical value assigned to an assessment of the color of the skin of a neonate. 0 = pale blue; 1 = pink body and pale blue extremities; 2 = pink body and extremities. C81274 Numeric Value C90259 NICHD Pediatric Terminology C39594 Skin Rash Skin Rash Any change in the skin which affects its appearance or texture. A rash may be localized to one part of the body, or affect all the skin. Rashes may cause the skin to change color, itch, become warm, bumpy, dry, cracked or blistered, swell and may be painful. C4876 Symptom C90259 NICHD Pediatric Terminology C73425 Sleep Sleep A natural and periodic state of rest during which consciousness of the world is suspended. C19988 Organismal Process C90259 NICHD Pediatric Terminology C3376 Sleep Disorder Sleep Disorder A change from the patient's baseline sleeping pattern, either an increase or a decrease in the number of hours slept. This can also refer to alterations in the stages of sleep. C9229 Systemic Disorder C90259 NICHD Pediatric Terminology C29719 Smoking History Smoking History A record of an individual's background in regard to smoking tobacco. This would include such factors as start date, end date (if applicable), number of cigarette smoked, attempts to quit, and others. C18772 Personal Medical History C90259 NICHD Pediatric Terminology C50746 Sneezing Sneezing A symptom consisting of the involuntary expulsion of air from the nose. C4876 Symptom C90259 NICHD Pediatric Terminology C34927 Social Phobia Social Anxiety Disorder An anxiety disorder characterized by an intense, irrational fear of one or more social or performance situations in which the individual believes that he or she will be scrutinized by others. Exposure to social situations immediately provokes an anxiety response. In adults, the social phobia is recognized as excessive or unreasonable. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology C81292 Social History Social History Past events that occurred between individuals and/or their communities. C18772 Personal Medical History C90259 NICHD Pediatric Terminology C34781 Spastic Diplegia Spastic Diplegia A type of cerebral palsy characterized by spasticity and hypertonia of the lower extremities bilaterally, particularly the legs, hips, and pelvis; this is the most common (70%) form of cerebral palsy. C34460 Cerebral Palsy C90259 NICHD Pediatric Terminology C35284 Specific Phobia Specific Phobia An anxiety disorder characterized by an intense, irrational fear cued by the presence or anticipation of a specific object or situation. Exposure to the phobic stimulus immediately provokes an anxiety response. In adults, the specific phobia is recognized as excessive or unreasonable. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology C5041 Speech Manifestations Speech Disorder A term referring to disorders characterized by the disruption of normal speech. It includes stuttering, lisps, dysarthria and voice disorders. C9229 Systemic Disorder C90259 NICHD Pediatric Terminology C92883 Spermicidal Cream Spermicidal Cream A vaginal cream that is deleterious to sperm. C92886 Spermicide C90259 NICHD Pediatric Terminology C92884 Spermicidal Foam Spermicidal Foam A vaginal foam that is deleterious to sperm. C92886 Spermicide C90259 NICHD Pediatric Terminology C92885 Spermicidal Jelly Spermicidal Jelly A vaginal jelly that is deleterious to sperm. C92886 Spermicide C90259 NICHD Pediatric Terminology C92886 Spermicide Spermicide A chemical product that is deleterious to sperms and can be in the form of either a jelly, foam, or cream. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C92887 Spinal Block Spinal Block A procedure in which a pharmaceutical agent is administered into the subarachnoid space, producing a loss of sensation at and below the level of the block. C64381 Regional Anesthesia Procedure C90259 NICHD Pediatric Terminology C92888 Spontaneous Rupture of Membrane Spontaneous Rupture of Membrane SROM The normal rupture of the amniotic sac in a full term pregnant mother at the onset of labor. C92874 Rupture of Membrane C90259 NICHD Pediatric Terminology C89520 Square Window Square Window When testing the newborn infant for neuromuscular maturity, the "square window" test measures wrist flexibility and resistance to extensor stretching, The examiner straightens the infant's fingers and applies gentle pressure on the dorsum of the hand, close to the fingers, and then estimates the angle between the palm of the hand and the forearm. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C92889 ST Waveform Analysis ST Waveform Analysis Technology STAN A method of fetal ECG surveillance during labor that monitors the ST segment, to indicate any fetal hypoxia. C92714 Fetal Examination C90259 NICHD Pediatric Terminology C92723 Stage of Labor Stages of Labor The various distinct periods of the labor and childbirth process. It involves uterine contractions and cervical dilation to expel the fetus and for the baby to be born. C21514 Temporal Qualifier C90259 NICHD Pediatric Terminology C81322 Step Reflex Step Reflex An involuntary, primal response in the neonate to take brisk steps when the feet are placed on a surface whilst in a supported standing position. C81181 Infant Reflex C90259 NICHD Pediatric Terminology C35040 Strabismus Strabismus Strabismus is the intermittent or constant misalignment of an eye so that its line of vision is not pointed at the same object as the other eye. Strabismus is caused by an imbalance in the extraocular muscles which control the positioning of the eyes. Strabismus is normal in newborns but should resolve by the time the baby is 6 months old. In older children with strabismus, the brain may learn to ignore the input from one eye, and this may lead to amblyopia, a potentially permanent decrease in vision in that eye if not corrected. C35126 Vision Disorder C90259 NICHD Pediatric Terminology C81293 Street Number Street Number The numeric or alphabetic identifier of a building on a thoroughfare. C16495 Demographics C90259 NICHD Pediatric Terminology C92857 Pregnancy Stretch Mark Stretch Marks The visible, linear scarring in the dermis, predominantly of the abdomen due to the stretching of tissue and related hormonal changes during pregnancy. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C92890 Stripping of Membrane Stripping of Membrane An intervention during labor and delivery, of gently sweeping the amniotic membrane to separate it from the attachment to the lower uterine segment. C92814 Induction of Labor C90259 NICHD Pediatric Terminology C38299 Subcutaneous Route of Administration Subcutaneous Route of Administration Drug administration beneath the skin. It provides for relatively slow, sustained release of the drug. The rate of absorption into the blood is perfusion-limited, proportional to the amount of drug at the site and can be enhanced by chemical or physical stimulation of blood flow. Subcutaneous administration minimizes the risks associated with intravascular injection: for subcutaneous infusions, external and implantable pumps are used. C38291 Parenteral Route of Administration C90259 NICHD Pediatric Terminology C81294 Submitting Facility Submitting Facility The hospital or medical institution that is submitting data or information. C16495 Demographics C90259 NICHD Pediatric Terminology C45306 Substance Substance A material with particular features. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C81323 Sucking Reflex Sucking Reflex An involuntary, primal response in the neonate when a nipple is placed on an infant's lips. C81181 Infant Reflex C90259 NICHD Pediatric Terminology C92892 Surgical Contraception Surgical Contraception Method A method of achieving contraception with the aid of a surgical procedure that prevents fertilization of an egg by a sperm. C37932 Contraception C15332 Gynecologic Surgical Procedure C90259 NICHD Pediatric Terminology C15384 Surgical Incision Surgical Incision An intentional cut made to an individual's body with the intent of performing a diagnostic or therapeutic intervention. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology C15329 Surgical Procedure Surgical Procedure A diagnostic or treatment procedure performed by manual and/or instrumental means, often involving an incision and the removal or replacement of a diseased organ or tissue; of or relating to or involving or used in surgery or requiring or amenable to treatment by surgery. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology C36172 Sweating Sweating The loss of a watery fluid, consisting mainly of sodium chloride and urea in solution, that is secreted by the sweat glands in the skin of mammals. C4876 Symptom C90259 NICHD Pediatric Terminology C4876 Symptom Symptom Subjective evidence of disease perceived by the patient. C3367 Finding C90259 NICHD Pediatric Terminology C87125 Syndactyly Syndactyly A congenital condition characterized by webbing between the fingers and/or toes, joining the digits together. In rare cases, the joining of the fingers or toes may involve bony fusion between the digits. Common causes include Down Syndrome and hereditary syndactyly. C89337 Congenital Abnormality of the Musculoskeletal System C90259 NICHD Pediatric Terminology C97151 Systemic Congenital Disorder Systemic Congenital Disorder An inherited disorder that presents with systemic manifestations. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology C9229 Systemic Disease Systemic Disorder A clinical course finding indicating that a disease presents with systemic manifestations. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C92911 Uterine Tachysystole Tachysystole A frequency of uterine contraction that is higher than normal. C92904 Uterine Contraction C90259 NICHD Pediatric Terminology C16847 Technique Technique A practiced and regimented skill or series of actions. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology C92939 Teenage Pregnancy Teenage Pregnancy A pregnancy in an adolescent between the ages of thirteen and nineteen. C92933 Normal Pregnancy C90259 NICHD Pediatric Terminology C40978 Telephone Number Telephone Number A sequence of decimal digits (0-9) that is used for identifying a destination telephone line or other device in a telephone network. C90492 Personal Information C90259 NICHD Pediatric Terminology C25206 Temperature Temperature A measure of the average kinetic energy of a system of particles. Temperature may be quantified, in the context of thermodynamics, as the potential of one system to transfer thermal energy to another system until both systems reach a state of thermal equilibrium. C25447 Characteristic C90259 NICHD Pediatric Terminology C21514 Temporal Qualifier Temporal Qualifier Terms used to indicate units of time or other terms associated with time. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C85185 Tetanus Tetanus A serious infectious disorder that follows wound contamination by the Gram-positive bacterium Clostridium tetani. The bacteria produce a neurotoxin called tetanospasmin, which causes muscle spasm in the jaw and other anatomic sites. C2890 Bacterial Disease C90259 NICHD Pediatric Terminology C96405 Tetanus and Diphtheria Toxoids Adsorbed Tetanus and Diphtheria Toxoids Adsorbed A sterile, intramuscular suspension of alum (aluminum potassium sulfate)-precipitated toxoids indicated for active immunization for the prevention of tetanus and diphtheria for use in persons 7 years of age or older. C96398 Toxoid Vaccine C90259 NICHD Pediatric Terminology C2660 Tetanus Toxoid Vaccine Tetanus Toxoid Vaccine A preparation of formaldehyde-deactivated toxin isolated from the bacterium Clostridium tetani. Tetanus toxoid is used for booster injection and can stimulate the production of antitoxin antibodies. This agent may be used as an adjuvant in cancer vaccines. C96398 Toxoid Vaccine C90259 NICHD Pediatric Terminology C92894 Therapeutic Abortion Procedure Therapeutic Abortion Intentional end of pregnancy by the removal or expulsion of a fetus or embryo from the uterus to preserve the health of the gravida (pregnant female). C89340 Obstetric Procedure C90259 NICHD Pediatric Terminology C49236 Therapeutic Procedure Therapeutic Procedure An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology C92895 Third Stage of Labor Third Stage of Labor Placental Stage A stage during labor and childbirth that starts with the birth of the baby and ends with the delivery of the placenta. C92723 Stages of Labor C90259 NICHD Pediatric Terminology C92896 Third Trimester Third Trimester The period of gestation that ranges from the 28th week of pregnancy until delivery. C69121 Trimester C90259 NICHD Pediatric Terminology C12799 Thorax Thorax The division of the body lying between the neck and the abdomen. C32221 Body Part C90259 NICHD Pediatric Terminology C3408 Thrombocytopenia Thrombocytopenia A condition in which there is an abnormally small number of platelets in the circulating blood. C26323 Hematological Disorder C90259 NICHD Pediatric Terminology C84479 Excessive Blood Clotting Thrombophilia A condition characterized by an abnormally high level of thrombi. Causes include thrombotic thrombocytopenic purpura, disseminated intravascular coagulation, bone marrow disorders, and antiphospholipid antibody syndrome. C26323 Hematological Disorder C90259 NICHD Pediatric Terminology C85189 Thyroglossal Duct Cyst Thyroglossal Duct Cyst A congenital benign cyst arising from the remnants of the thyroglossal duct. It is usually located in the midline of the neck. C2978 Cyst C90259 NICHD Pediatric Terminology C64813 Thyrotropin Measurement Thyrotropin Measurement A quantitative measurement of the amount of thyrotropin present in a sample. C25294 Laboratory Procedure C90259 NICHD Pediatric Terminology C25207 Time Time The continuum of experience in which events pass from the future through the present to the past. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C92897 Tocodynamometry Tocodynamometry The recording of uterine muscle contractions during pregnancy and labor. C16847 Technique C90259 NICHD Pediatric Terminology C89342 Toddler Toddler A child that is approximately between 12 and 18 months of age. C42708 Child C90259 NICHD Pediatric Terminology C89890 Toddler Stage Toddler Stage The period of life between 13 months and 2 years of age. A human life stage that begins at thirteen months of age and continues until twenty-four complete months of age. C89345 Child Life Stage C90259 NICHD Pediatric Terminology C33788 Toe Toe One of the terminal digits of the foot. C32221 Body Part C90259 NICHD Pediatric Terminology C81324 Tonic Neck Reflex Tonic Neck Reflex An involuntary, primal response in the neonate in which the arm extends to follow the infant's gaze, while the opposing arm and leg flex inward. C81181 Infant Reflex C90259 NICHD Pediatric Terminology C81298 Total Body Length Total Body Length The total linear extent of the body. C25334 Length C90259 NICHD Pediatric Terminology C74794 Total Thyroxine Measurement Total Thyroxine Measurement The determination of the amount of free and bound thyroxine present in a sample. C25294 Laboratory Procedure C90259 NICHD Pediatric Terminology C35078 Tourette Syndrome Tourette's Syndrome A neurologic disorder caused by defective metabolism of the neurotransmitters in the brain. It is characterized by repeated involuntary movements (motor tics) and uncontrollable vocal sounds (vocal tics). The symptoms are usually manifested before the age of eighteen. C96412 Brain Development Abnormality C90259 NICHD Pediatric Terminology C34943 Toxemia of Pregnancy Toxemia A pregnancy induced hypertensive state that occurs after 20 weeks of gestation characterized by an increase in blood pressure, along with body swelling and proteinuria. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C96398 Toxoid Vaccine Toxoid Vaccine Any vaccine that contains an inactivated toxic substance used for disease prophylaxis or to vaccinate against snake bites. C923 Vaccine C90259 NICHD Pediatric Terminology C3418 Toxoplasmosis Toxoplasmosis A parasitic disease contracted by the ingestion or fetal transmission of toxoplasma gondii. C27864 Parasitic Disease C90259 NICHD Pediatric Terminology C81325 Transferase Deficiency Galactosemia Transferase Deficient Galactosemia A disorder characterized by the body's inability to metabolize galactose. This type of galactosemia is caused by germline mutations in the GALT gene which leads to the inhibition in the activity of the enzyme galactose-1-phosphate uridyl transferase. C34816 Congenital Metabolic Disorder C90259 NICHD Pediatric Terminology C92942 Transition Phase of Labor Transitional Phase of Labor The period during the first stage of labor and childbirth that involves strong uterine contractions and maximal cervical dilatation. C92798 First Stage of Labor C90259 NICHD Pediatric Terminology C92898 Transverse Fetal Presentation Transverse Fetal Presentation A fetal position during delivery in which the alignment of the spine of the fetus is not parallel to the mother's spine. C92724 Fetal Presentation C90259 NICHD Pediatric Terminology C92899 Transverse Occiput Presentation Transverse Occiput A fetal position during delivery in which the face is towards one of the mother's thighs while descending into the birth canal. C92926 Fetal Position C90259 NICHD Pediatric Terminology C38038 Tremor Tremor The shaking movement of the whole body or just a certain part of it, often caused by problems of the neurons responsible for muscle action. C4876 Symptom C90259 NICHD Pediatric Terminology C69121 Trimester Trimester A period of three months; especially one of the three three-month periods into which human pregnancy is divided. C92858 Pregnancy Time Period C90259 NICHD Pediatric Terminology C92900 Triple Screen Triple Screen A screening method in which maternal blood levels of alpha-fetoprotein, unconjugated estriol and human chorionic gonadotrophin are calculated. The results are subsequently evaluated in relation to the mother's age, weight and fetal gestational age. C92803 Screening for Genetic Defect C90259 NICHD Pediatric Terminology C2643 Trivalent Influenza Vaccine Trivalent Influenza Vaccine Flu prevention|Flu prophylaxis|Flu shot|Flu vaccination A synthetic vaccine consisting of three inactivated influenza viruses, two different influenza type A strains and one influenza type B strain. Trivalent influenza vaccine is formulated annually, based on influenza strains projected to be prevalent in the upcoming flu season. This agent may be formulated for injection or intranasal administration. C2848 Polyvalent Vaccine C90259 NICHD Pediatric Terminology C92901 Tubal Ligation Tubal Ligation A method of female sterilization where the fallopian tubes are surgically ligated to prevent conception. C92892 Surgical Contraception Method C90259 NICHD Pediatric Terminology C92946 Tubal Pregnancy Tubal Pregnancy An ectopic pregnancy that occurs in the fallopian tube instead of the uterine corpus. Causes include pelvic inflammatory disease and prior pelvic surgery. It may result in severe abdominal pain, vaginal bleeding, and tubal rupture. C34945 Ectopic Pregnancy C90259 NICHD Pediatric Terminology C97126 Ty21a Typhoid Vaccine Ty21a Typhoid Vaccine A live attenuated oral virus vaccine used to prevent typhoid, which is caused by Salmonella typhi. C62761 Attenuated Live Bacterial Vaccine C90259 NICHD Pediatric Terminology C35089 Typhoid Fever Typhoid Fever A bacterial infectious disorder contracted by consumption of food or drink contaminated with Salmonella typhi. This disorder is common in developing countries and can be treated with antibiotics. C2890 Bacterial Disease C90259 NICHD Pediatric Terminology C17230 Ultrasonography Ultrasound Imaging Ultrasound A technique in which high-frequency sound waves are bounced off internal organs and the echo pattern is converted into a 2 dimensional picture of the structures beneath the transducer. C18020 Diagnostic Procedure C16847 Technique C90259 NICHD Pediatric Terminology C92902 Umbilical Cord Compression Umbilical Cord Compression An abnormal situation in utero, when there is increased pressure on the umbilical cord, which constricts blood supply to the fetus. C81236 Birth Complication C90259 NICHD Pediatric Terminology C87126 Umbilical Cord Prolapse Umbilical Cord Prolapse Prolapsed Cord An obstetric emergency when the umbilical cord is pushed into the vagina ahead of the baby and becomes compressed, cutting off the flow of blood to the baby. C81236 Birth Complication C90259 NICHD Pediatric Terminology C12326 Undescended Testis Undescended Testis The failure of one or both testes of a male fetus to descend from the abdomen into the scrotum during the late part of pregnancy. If not surgically corrected in early childhood, males may be at increased risk for testicular cancer later in life. C35107 Congenital Abnormality of the Genitourinary System C90259 NICHD Pediatric Terminology C25709 Unit of Measure Unit of Measure A named quantity in terms of which other quantities are measured or specified, used as a standard measurement of like kinds. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C77606 Unit per Gram Unit per Gram An arbitrary unit of substance content expressed in unit(s) per gram. C25709 Unit of Measure C90259 NICHD Pediatric Terminology C92903 Urge to Push Urge to Push A characteristic sign of impending birth in the mother during the second stage of labor; she feels like bearing down due to the pressure of the baby in the birth canal. C92881 Signs of Impending Birth C90259 NICHD Pediatric Terminology C3430 Urinary System Disorder Urinary System Disorder Disorders of any part of the urologic system. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C50791 Urinary Tract Infection Urinary Tract Infection A bacterial infectious process affecting any part of the urinary tract, most commonly the bladder and the urethra. Symptoms include urinary urgency and frequency, burning sensation during urination, lower abdominal discomfort, and cloudy urine. C3430 Urinary System Disorder C90259 NICHD Pediatric Terminology C30010 US State US State One of the fifty states which is a member of the federation known as the United States of America. Other US geographic areas, such as Puerto Rico and the District of Columbia, are essentially equivalent to State when used in an address. C16495 Demographics C90259 NICHD Pediatric Terminology C92904 Uterine Contraction Uterine Contraction A tightening of the involuntary smooth muscles of the uterus. C92819 Intrapartum Process C90259 NICHD Pediatric Terminology C92909 Uterine Involution Uterine Involution Atrophy or reduction of the size of the uterine corpus. C92935 Postpartum Process C90259 NICHD Pediatric Terminology C92910 Uterine Souffle Uterine Souffle A soft murmur heard in auscultating a pregnant uterus. It is caused by the increased vascularity of pregnancy. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C923 Vaccine Vaccine Preparations containing substances with antigenic properties administered to activate the immune system, thereby inducing an immune response. Vaccines range from inactivated or attenuated microorganisms (bacteria and viruses), enhanced autologous tumor cells, tumor antigens or epitopes that are used to elicit host immune responses. Vaccines are used for the prevention, amelioration, or treatment of infectious diseases and cancer. C307 Biologic Agent C90259 NICHD Pediatric Terminology C81300 Vacuum Assisted Vaginal Delivery Vacuum Assisted Vaginal Delivery The method referring to the delivery of a fetus through the vaginal canal with assistance of a vacuum extractor device. C81301 Vaginal Assisted Delivery C90259 NICHD Pediatric Terminology C81301 Vaginal Assisted Delivery Vaginal Assisted Delivery The method referring to the use of medical devices such as vacuum extractor or forceps to assist with the delivery of a fetus. C81303 Vaginal Delivery C90259 NICHD Pediatric Terminology C81302 Vaginal Birth after Cesarean Vaginal Birth after Cesarean The method referring to the delivery of a fetus through the vaginal canal after the mother has had a cesarean delivery with a previous pregnancy. C81303 Vaginal Delivery C90259 NICHD Pediatric Terminology C92912 Vaginal Birth Mechanism Vaginal Birth Mechanism The natural processes involved in giving birth vaginally. C92934 Labor and Delivery Process C90259 NICHD Pediatric Terminology C92913 Vaginal Bleeding during Pregnancy Vaginal Bleeding Hemorrhage from the vagina that may range from light spotting to heavy flow during pregnancy. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C81303 Vaginal Delivery Vaginal Delivery The method referring to the delivery of a fetus through the vaginal canal. C81179 Delivery Procedure C90259 NICHD Pediatric Terminology C42767 Vaginal Diaphragm Vaginal Diaphragm A medical contraceptive device of soft flexible material, usually of thin rubber, that is designed to cover the cervix uteri prior to sexual intercourse to prevent the entry of spermatozoa. To enhance efficacy, a spermicidal agent is often placed within the device. Antimicrobial agent(s) can also be used to prevent sexually transmitted diseases. Efficacy of vaginal diaphragm against infections is very limited. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C91199 Vaginal Ring Dosage Form Vaginal Ring A ring composed of active and/or inert ingredient(s), intended for administration in or around the vagina. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C92914 Variable Fetal Heart Rate Deceleration Variable Deceleration An irregular decrease in the fetal heart rate after the peak of an uterine contraction. C92789 Fetal Heart Rate Deceleration C90259 NICHD Pediatric Terminology C96395 Varicella Vaccine Varicella Vaccine Chickenpox Vaccine|Shingles Vaccine A live attenuated virus vaccine used to prevent chickenpox and shingles, which is caused by varicella-zoster virus (VZV). C1920 Attenuated Live Virus Vaccine C90259 NICHD Pediatric Terminology C71091 Human Herpesvirus 3 Varicella-Zoster Virus An icosahedral, enveloped virus containing a single molecule of linear double-stranded DNA of 125000 nucleotides that infects only humans. It is the causative agent of chickenpox and shingles. C14283 Virus C90259 NICHD Pediatric Terminology C87127 Vasa Previa Vasa Previa A serious condition in which blood vessels of the umbilical cord or the placenta cross the entrance to the birth canal, beneath the fetus; this can lead to rapid fetal blood loss during labor and delivery if the blood vessels tear as the cervix dilates and the membranes rupture. C81236 Birth Complication C90259 NICHD Pediatric Terminology C15348 Vasectomy Vasectomy Surgical removal of part or all of the vas deferens. C92892 Surgical Contraception Method C90259 NICHD Pediatric Terminology C81184 Vernier Caliper Vernier Caliper A medical device that is a combination of ruler and caliper that can measure the distance between two points. The configuration of this device permits the measurement of internal dimensions. C81182 Measurement Device C90259 NICHD Pediatric Terminology C34328 Vernix Caseosa Vernix Caseosa A white cheese-like protective material that covers the skin of a fetus. C13236 Biological Substance C90259 NICHD Pediatric Terminology C12998 Vertebral Column Vertebral Column A series of bones, muscles, tendons, and other tissues reaching from the base of the skull to the tailbone. The vertebral column forms the axis of the skeleton and encloses as well as protects the spinal cord and the fluid surrounding the spinal cord. C32221 Body Part C90259 NICHD Pediatric Terminology C92917 Vertex Presentation Vertex Presentation A fetal position during delivery in which the head of the fetus is flexed and it is first to descend into the birth canal. C92748 Cephalic Presentation C90259 NICHD Pediatric Terminology C97127 Vi Capsular Polysaccharide Typhoid Vaccine Vi Capsular Polysaccharide Typhoid Vaccine A live attenuated injectable virus vaccine used to prevent typhoid, which is caused by Salmonella typhi. C97125 Polysaccharide Vaccine C90259 NICHD Pediatric Terminology C3439 Viral Infection Viral Disease Viral Infection Any disease caused by a virus. C26726 Infectious Disease C90259 NICHD Pediatric Terminology C14283 Virus Virus An infectious agent which consists of two parts, genetic material and a protein coat. These organisms lack independent metabolism, and they must infect the cells of other types of organisms to reproduce. Most viruses are capable of passing through fine filters that retain bacteria, and are not visible through a light microscope. C14250 Organism C90259 NICHD Pediatric Terminology C35126 Vision Disorder Vision Disorder Visual impairments limiting one or more of the basic functions of the eye: visual acuity, dark adaptation, color vision, or peripheral vision. These may result from eye diseases, optic nerve diseases, visual pathway diseases, occipital lobe diseases, ocular motility disorders' and other conditions. C63711 Sensory Disorder C90259 NICHD Pediatric Terminology C35275 Visual Cortex Disorder Visual Cortex Disorder Cortical Visual Impairment A vision disorder that results from damage of the part of the cerebral cortex that is involved in the processing of visual information. C35126 Vision Disorder C90259 NICHD Pediatric Terminology C49672 Vital Signs Vital Sign Measurement A character or string that represents the vital signs examination. C18020 Diagnostic Procedure C90259 NICHD Pediatric Terminology C943 Vitamin K Vitamin K The term "vitamin K" refers to a group of chemically similar fat-soluble compounds called naphthoquinones: vitamin K1 (phytonadione) is found in plants and is the primary source of vitamin K for humans through dietary consumption, vitamin K2 compounds (menaquinones) are made by bacteria in the human gut, and vitamin K3 (menadione) is a water-soluble preparation available for adults only. Vitamin K is necessary for the liver to produce the coagulation factors II, VII, IX, and X, as well as the clotting factors protein C, protein S, and protein Z; vitamin K deficiency can result in deficiencies of these coagulation factors and excess bleeding. An injection of vitamin K is routinely given to newborn infants to prevent vitamin K deficiency bleeding, also known as hemorrhagic disease of the newborn. Vitamin K deficiency is rare in adults but may result from chronic malnutrition or an inability to absorb dietary vitamins. C45306 Substance C90259 NICHD Pediatric Terminology C3442 Vomiting Vomiting The reflex act of ejecting the contents of the stomach through the mouth. C4876 Symptom C90259 NICHD Pediatric Terminology C87128 Watery Stool Watery Stool Frequent, loose, and watery stools are noted in most infants, even if they are fed formula, until they are six to eight weeks old; after that, the stools become firmer and less frequent. C4876 Symptom C90259 NICHD Pediatric Terminology C87129 Weak Breathing Weak Breathing Shallow inhalations and exhalations that indicate respiratory distress. C4876 Symptom C90259 NICHD Pediatric Terminology C62754 Weight Gain Weight Gain An increase in overall body mass. C92720 Pregnancy Finding C90259 NICHD Pediatric Terminology C78718 Wheezing Wheezing A symptom and a finding during physical examination, characterized by a high-pitched, whistling sound during breathing. It results from the narrowing or obstruction of the respiratory airways. The most common causes of wheezing are asthma, chronic obstructive pulmonary disease, tracheobronchitis, and pulmonary edema. C4876 Symptom C90259 NICHD Pediatric Terminology C92919 Withdrawal Contraception Withdrawal Contraception A birth control method adopted during sexual intercourse by withdrawing the penis from the vagina before ejaculation. C37932 Contraception C90259 NICHD Pediatric Terminology C87131 Yawning Yawning An involuntary deep inhalation with the mouth open, often a sign of drowsiness or boredom. C4876 Symptom C90259 NICHD Pediatric Terminology C96396 Yellow Fever Vaccine Yellow Fever Vaccine A live, attenuated viral vaccine to prevent yellow fever, endemic to parts of Africa and South America. C1920 Attenuated Live Virus Vaccine C90259 NICHD Pediatric Terminology C35547 Yellow Fever Virus Infection Yellow Fever Virus Infection A viral infection caused by a flavivirus called yellow fever virus. It is transmitted to humans from infected mosquitoes. The signs and symptoms range from a mild febrile illness to liver damage with jaundice and hemorrhages. C3439 Viral Disease C90259 NICHD Pediatric Terminology C49488 Yes Yes The affirmative response to a question. C25180 Indicator C90259 NICHD Pediatric Terminology C92921 Abdominal Pregnancy Abdominal Pregnancy Ectopic pregnancy characterized by the implantation of the embryo in the peritoneal cavity or abdominal organs. C34945 Ectopic Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C92725 Abnormal Fetal Attitude Abnormal Fetal Attitude An abnormality in the position of the fetus during the labor and delivery process. C92713 Fetal Attitude C92712 NICHD Pregnancy & Childbirth Terminology C92726 Abnormal Pregnancy Abnormal Pregnancy A pregnancy that is complicated and affected by an abnormal finding or disease condition in either the fetus and/or the mother. C27020 Female Reproductive System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C35221 Abortion Finding Abortion Any termination of pregnancy happening before the fetus is able to sustain independent life. C90491 Pregnancy Outcome C92712 NICHD Pregnancy & Childbirth Terminology C92943 Active Phase of Labor Active Phase of Labor The period during the first stage of labor and childbirth involved with cervical dilatation, effacement, and fetal station. C92798 First Stage of Labor C92712 NICHD Pregnancy & Childbirth Terminology C92727 Alcohol Related Birth Defect Alcohol Related Birth Defects A physical or cognitive mental abnormality caused by maternal alcohol consumption and its toxic effect on the developing embryo during pregnancy. C92780 Fetal Alcohol Spectrum Disorder C92712 NICHD Pregnancy & Childbirth Terminology C92728 Alcohol Related Neurodevelopmental Disorder Alcohol Related Neurodevelopmental Disorder A cognitive and neurological disorder due to fetal intrauterine exposure to maternal alcohol consumption. Typically, this presents without facies or other growth abnormalities. C92780 Fetal Alcohol Spectrum Disorder C92712 NICHD Pregnancy & Childbirth Terminology C74732 Alpha-fetoprotein Measurement Alpha-fetoprotein Measurement The determination of the amount of alpha-fetoprotein present in a sample. C92745 Blood Test for Protein Level C92712 NICHD Pregnancy & Childbirth Terminology C52009 Amniocentesis Amniocentesis A prenatal diagnostic procedure in which a small sample of amniotic fluid is removed from the uterus by a needle inserted into the abdomen. This procedure is used to detect various genetic abnormalities in the fetus and/or the sex of the fetus. C92803 Screening for Genetic Defect C92712 NICHD Pregnancy & Childbirth Terminology C92729 Amnioinfusion Amnioinfusion The procedure of instilling saline or other fluids into the amniotic cavity using an intrauterine catheter. C89340 Obstetric Procedure C92712 NICHD Pregnancy & Childbirth Terminology C13188 Amniotic Fluid Amniotic Fluid The fluid within the amniotic cavity which surrounds and protects the developing embryo. It is initially produced by the amnion and then later by the lungs and kidneys. The amount at term normally varies from 500 to 2000 ml. C13236 Biological Substance C92712 NICHD Pregnancy & Childbirth Terminology C97167 Anemia of Prematurity Anemia of Prematurity A blood disorder characterized by low hemoglobin levels in premature neonates that usually spontaneously resolves within 3-6 months post birth. A combination of factors including the transition from the liver to the bone marrow for erythropoiesis in a neonate, blood loss experienced during delivery, the shortened life span of fetal blood cells, and an acclimation to a relatively hyperoxic environment outside the womb can predispose a neonate to this condition. C35729 Congenital Abnormality of the Circulatory System C92712 NICHD Pregnancy & Childbirth Terminology C15181 Anesthesia Procedure Anesthesia Procedure Treatment with a pharmacological substance that produces a loss of feeling. C25218 Intervention or Procedure C92712 NICHD Pregnancy & Childbirth Terminology C92730 Angular Pregnancy Angular Pregnancy A type of pregnancy which starts with the embryo in the interstitial section of the fallopian tube, which then grows into the uterine cavity. C34945 Ectopic Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C92731 Antepartum Antepartum The period of time preceding labor and delivery. C92858 Pregnancy Time Period C92712 NICHD Pregnancy & Childbirth Terminology C92732 Anterior Occiput Presentation Anterior Occiput Occiput Anterior A fetal position during delivery in which the head of the fetus faces the mother's back. C92926 Fetal Position C92712 NICHD Pregnancy & Childbirth Terminology C92733 Appropriate for Gestational Age Appropriate for Gestational Age An assessment of the fetus or the newborn infant for growth and size that is considered within normal ranges. C92711 Fetal Finding C92712 NICHD Pregnancy & Childbirth Terminology C16739 Artificial Insemination Artificial Insemination Introduction of sperm into the female reproductive tract by artificial means in order to achieve fertilization. C92930 Conception Method C92712 NICHD Pregnancy & Childbirth Terminology C92734 Artificial Rupture of Membrane Artificial Rupture of Membrane AROM An external intervention during labor and delivery to break the bag of membranes or the amniotic sac to facilitate childbirth. C92814 Induction of Labor C92712 NICHD Pregnancy & Childbirth Terminology C92735 Assessment of Fetal Attitude Assessment of Fetal Attitude A method to find the position of the fetal head in the uterine cavity in its descent during labor. C92920 Assessment of Fetal Condition C92712 NICHD Pregnancy & Childbirth Terminology C92920 Assessment of Fetal Condition Assessment of Fetal Condition A method to determine health status of fetus; it includes prenatal diagnostic methods and obstetrical management. C90341 Pediatric Intervention or Procedure C92712 NICHD Pregnancy & Childbirth Terminology C92736 Assessment of Fetal Heart Condition Assessment of Fetal Heart Condition The monitoring of the fetal heart to determine the cardiac status and health of the fetus during pregnancy and labor. C92920 Assessment of Fetal Condition C92712 NICHD Pregnancy & Childbirth Terminology C92737 Assessment of Fetal Presentation Assessment of Fetal Presentation A series of maneuvers to determine the position and presenting part of the fetus with respect to the maternal pelvic canal in preparation for labor and the birth process. C92920 Assessment of Fetal Condition C92712 NICHD Pregnancy & Childbirth Terminology C92738 Assisted Labor Assisted Labor An intervention during the childbirth process to help the laboring mother deliver her baby. C89340 Obstetric Procedure C92712 NICHD Pregnancy & Childbirth Terminology C85573 Auscultation Auscultation Listening with a device, such as a stethoscope, to anatomical locations that produce audible sounds like the heart, lungs and abdomen. C18020 Diagnostic Procedure C92712 NICHD Pregnancy & Childbirth Terminology C92739 Back Labor Back Labor A type of labor where the labor pain or discomfort is felt by the pregnant mother in her back. C4876 Symptom C92712 NICHD Pregnancy & Childbirth Terminology C92740 Bacterial Vaginosis Screening Bacterial Vaginosis Screen A test done during pregnancy for the presence of Gardnerella vaginalis, Ureaplasma urealyticum, Mycoplasma hominis, Mobiluncus, Prevotella and anaerobic bacteria. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C92741 Baseline Fetal Heart Rate Baseline Fetal Heart Rate The number of fetal cardiac beats per minute, considered as the reference value against which measurements in the future can be made. C92716 Fetal Heart Rate C92712 NICHD Pregnancy & Childbirth Terminology C92781 Fetal Heart Beat to Beat Variability Beat to Beat Variability A fetal heart monitor finding where there is a change in the beats per minute from one fetal heart beat to the next. C92790 Fetal Heart Rate Variability C92712 NICHD Pregnancy & Childbirth Terminology C305 Bilirubin Bilirubin A dark orange, yellow pigment that is the product of the breakdown of iron in the blood; it is conjugated in the liver and excreted in the bile. C13236 Biological Substance C92712 NICHD Pregnancy & Childbirth Terminology C13236 Body Fluid or Substance Biological Substance Material produced by living organisms; it can be a necessary constituent of, or product of an organismal process. C45306 Substance C92712 NICHD Pregnancy & Childbirth Terminology C25155 Birth Birth The event of being born. C92934 Labor and Delivery Process C92712 NICHD Pregnancy & Childbirth Terminology C81236 Birth Complication Birth Complication The development of a problematic medical situation that occurs concurrently with the birth of a neonate. C92718 Finding during Childbirth Labor C92712 NICHD Pregnancy & Childbirth Terminology C28133 Blood Cell Count Blood Cell Count The determination of the number of red blood cells, white blood cells, and platelets in a blood sample. C47868 Blood Test C92712 NICHD Pregnancy & Childbirth Terminology C92744 Blood Glucose Measurement Blood Glucose Measurement A quantitative measurement for assessing the amount of glucose present in a blood sample. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C54706 Blood Pressure Blood Pressure The pressure of the circulating blood against the walls of the blood vessels. C25447 Characteristic C92712 NICHD Pregnancy & Childbirth Terminology C47868 Blood Chemistry Measurement Blood Test The determination of the measured concentrations of chemical constituents of the blood by assay in a clinical laboratory. C18020 Diagnostic Procedure C92712 NICHD Pregnancy & Childbirth Terminology C92745 Blood Protein Measurement Blood Test for Protein Level A quantitative measurement for assessing the amount of protein present in a blood sample. C47868 Blood Test C92712 NICHD Pregnancy & Childbirth Terminology C61009 Blood Type Blood Type The specific reaction pattern of erythrocytes of an individual to the antisera of one blood group; e.g., the ABO blood group consists of four major blood types: O, A, B, and AB. This classification depends on the presence or absence of two major antigens: A or B. Type O occurs when neither is present and type AB when both are present. The blood type is the genetic phenotype of the individual for one blood group system and may be determined using different antisera available for testing. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C92742 Birth Partner Coached Method of Delivery Bradley Method A method of birth coaching in assisting the mother by her partner, to relieve her distress during labor and delivery by applying relaxation techniques and encouraging abdominal breathing. C92738 Assisted Labor C92712 NICHD Pregnancy & Childbirth Terminology C92746 Breast Engorgement Breast Engorgement A painful swelling of the breasts due to accumulation of milk in blocked lactating ducts. C92935 Postpartum Process C92712 NICHD Pregnancy & Childbirth Terminology C92855 Pregnancy Breast Soreness Breast Soreness The tenderness of the breasts during pregnancy due to changes in the hormonal levels and increased breast tissue growth. C92771 Early Pregnancy Symptoms C92712 NICHD Pregnancy & Childbirth Terminology C34438 Breech Presentation Breech Presentation A type of fetal presentation when the baby descends into the birth canal with hips, buttocks or its foot first during delivery. C92793 Malpresentation of Fetus C92712 NICHD Pregnancy & Childbirth Terminology C90599 Bronchopulmonary Dysplasia Bronchopulmonary Dysplasia A non-neoplastic lung disorder which develops in premature neonates who have been treated with oxygen and mechanical ventilation. C97173 Congenital Abnormality of the Respiratory System C92712 NICHD Pregnancy & Childbirth Terminology C92747 Bulging Perineum Bulging Perineum The protrusion in the perineal area during the second stage of labor. It is the characteristic sign of impending birth and is caused by increased pressure in the region. C92881 Signs of Impending Birth C92712 NICHD Pregnancy & Childbirth Terminology C92753 Cesarean Hysterectomy Caesarean Hysterectomy Surgical removal of uterus as a concurrent procedure after a cesarean delivery. C15256 Hysterectomy C92712 NICHD Pregnancy & Childbirth Terminology C46088 Caesarian Section Caesarian Section C-Section The delivery of an infant through a surgical abdominal incision. Surgery is performed when there may be complications associated with a vaginal birth and increased risk to the mother or fetus. C81179 Delivery Procedure C92712 NICHD Pregnancy & Childbirth Terminology C87067 Caput Succedaneum Caput Succedaneum A diffuse swelling of the scalp in a newborn, usually caused by the trauma of the scalp pushing through a narrowed cervix during birth. The swelling may extend across the midline of the scalp and may exhibit discoloration or bruising. C81236 Birth Complication C92712 NICHD Pregnancy & Childbirth Terminology C50484 Fetal Cephalhematoma Cephalhematoma A subperiosteal hemorrhage limited to the surface of one cranial bone, a usually benign condition seen in the newborn as a result of bone trauma. C81236 Birth Complication C92712 NICHD Pregnancy & Childbirth Terminology C92748 Cephalic Presentation Cephalic Presentation A fetal position during delivery in which the head of the fetus descends into the maternal pelvis. C92724 Fetal Presentation C92712 NICHD Pregnancy & Childbirth Terminology C92749 Cephalo-Pelvic Disproportion Cephalo-Pelvic Disproportion An abnormal condition during labor when the diameter of the fetal head is larger than the maternal pelvic canal; thus it is dangerous or impossible for the fetus to progress to a vaginal method of delivery. C81236 Birth Complication C92712 NICHD Pregnancy & Childbirth Terminology C92757 Contraceptive Cap Cervical Contraceptive Cap A medical device with a small rubber cap that fits over the cervix to block sperm from entering the cervical os. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C92750 Cervical Dilation Cervical Dilation A stretching and opening of the cervical os during childbirth in preparation for delivery of the baby; the diameter is measured in centimeters. C92819 Intrapartum Process C92712 NICHD Pregnancy & Childbirth Terminology C92751 Cervical Effacement Cervical Effacement A shortening and thinning of cervix due to the action of uterine contractions during active labor to allow for fetal descent. C92819 Intrapartum Process C92712 NICHD Pregnancy & Childbirth Terminology C92754 Change in Uterine Shape Change in Uterine Shape A variation in the dimensions of the uterus. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C92915 Varicella Zoster Virus Immunization Chickenpox Immunization The administration of a live attenuated viral vaccine to prevent herpes zoster infection. C15258 Immunization C92712 NICHD Pregnancy & Childbirth Terminology C26720 Chorioamnionitis Chorioamnionitis Inflammation of the fetal sac membranes. C27020 Female Reproductive System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C92755 Chorionic Villus Sampling Chorionic Villus Sampling The extraction of placenta tissue containing the chorionic villi from the maternal uterus in early pregnancy to screen for fetal genetic defects. C92803 Screening for Genetic Defect C92712 NICHD Pregnancy & Childbirth Terminology C32348 Colostrum Colostrum A thick, protein-rich substance secreted by the breasts during the second half of pregnancy and for a few days after birth before the breast milk comes in. It contains antibodies which serve to give the baby protection from disease and also has a laxative effect on the colon which helps to expel the plug of meconium and facilitate the establishment of normal bowel movements. C13236 Biological Substance C92712 NICHD Pregnancy & Childbirth Terminology C92756 Compound Fetal Presentation Compound Presentation A fetal position during delivery in which there are multiple fetal body parts that descends down the birth canal along with the main presenting part. Usually, this includes usually an extremity. C92793 Malpresentation of Fetus C92712 NICHD Pregnancy & Childbirth Terminology C16465 Conception Conception Fertilization of an ovum by a spermatozoon resulting in formation of a viable zygote. C21173 Reproductive Process C92712 NICHD Pregnancy & Childbirth Terminology C92930 Method of Conception Conception Method The process of conceiving a baby. C89340 Obstetric Procedure C92712 NICHD Pregnancy & Childbirth Terminology C28258 Condom Condom A contraceptive device consisting of a thin rubber or latex sheath worn over the penis during intercourse. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C37932 Contraception Contraception The prevention of conception or impregnation by the use of devices or drugs or surgery. C15843 Preventive Intervention C92712 NICHD Pregnancy & Childbirth Terminology C92758 Contraceptive Coil Contraceptive Coil Loop A medical device that is inserted into the uterus to prevent pregnancy. C42771 Intra Uterine Device C92712 NICHD Pregnancy & Childbirth Terminology C42734 Contraceptive Device Contraceptive Device A device designed to prevent conception through local or systemic effect, such as a barrier contraceptive, an intrauterine device, or a means of preventing ovulation (e.g., birth control pill). C62103 Device C92712 NICHD Pregnancy & Childbirth Terminology C92759 Contraceptive Implant Contraceptive Implant A drug implant that acts as a birth control device and which is inserted under the skin for drug delivery into the body. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C92760 Contraceptive Patch Contraceptive Patch A dermal patch that contains estrogen and progestin hormones for release and absorption through the skin and into the body to prevent pregnancy. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C69055 Contraceptive Sponge Contraceptive Sponge A sponge impregnated with an antispermicidal agent; it is designed to be placed into the vaginal canal to prevent live sperm from entering the uterus. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C92905 Uterine Contraction Frequency Contraction Frequency The number of uterine contractions recorded over a period of time, usually in minutes; measured from the start of one contraction to the start of the next. C70766 Quantitative Concept C92712 NICHD Pregnancy & Childbirth Terminology C92906 Uterine Contraction Intensity Contraction Intensity The duration of an uterine contraction expressed as mmHg. C70766 Quantitative Concept C92712 NICHD Pregnancy & Childbirth Terminology C92907 Uterine Contraction Interval Contraction Interval Relaxation Time between Uterine Contractions The time interval between uterine contractions during labor. C70766 Quantitative Concept C92712 NICHD Pregnancy & Childbirth Terminology C92908 Uterine Contraction Stress Test Contraction Stress Test A test done to check for the fetal well being after administering oxytocin or nipple stimulus to induce uterine contractions in the mother. An external fetal heart rate monitor is used to assess the fetal heart rate in response to the uterine contractions. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C92761 Cornual Pregnancy Cornual Pregnancy A type of pregnancy where the embryo develops in the cornu of uterus. C34945 Ectopic Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C92762 Crash Caesarean Section Crash Caesarean Section An emergency cesarean section that is carried out urgently in cases of fetal distress or severe maternal complication that is life threatening to either or both of them. C46088 Caesarian Section C92712 NICHD Pregnancy & Childbirth Terminology C92763 Crowning during Childbirth Crowning The characteristic sign of impending birth during the second stage of labor. The presenting part of the head of fetus is visible and firmly rimmed by the maternal vaginal wall. C92881 Signs of Impending Birth C92712 NICHD Pregnancy & Childbirth Terminology C92764 Cystic Fibrosis Carrier Screening Cystic Fibrosis Carrier Screening A genetic test to determine if either parent has the trait of cystic fibrosis carrier. C92803 Screening for Genetic Defect C92712 NICHD Pregnancy & Childbirth Terminology C92765 Deflexed Fetal Attitude Deflexed Attitude A position of the fetus during the labor and delivery process where the fetal back is straight, the head position is deflexed and upright on the spine. C92713 Fetal Attitude C92712 NICHD Pregnancy & Childbirth Terminology C92766 Delivery of Placenta Delivery of Placenta The natural process whereby the placenta detaches from the uterus. It occurs during the third stage of childbirth and shortly after delivery of the fetus. C92935 Postpartum Process C92712 NICHD Pregnancy & Childbirth Terminology C81179 Birth Method of Delivery Delivery Procedure Description of the method by which a fetus is delivered. C89340 Obstetric Procedure C92712 NICHD Pregnancy & Childbirth Terminology C2982 Depression Depression A melancholy feeling of sadness and despair. C2893 Psychiatric Disorder C92712 NICHD Pregnancy & Childbirth Terminology C92923 Development of Corpus Luteum Development of Corpus Luteum The process by which the ovarian follicle becomes the corpus luteum. It occurs after ovulation. C21173 Reproductive Process C92712 NICHD Pregnancy & Childbirth Terminology C92767 Dilated Anus Dilated Anus A characteristic sign of impending birth where the anal opening becomes wider due to increased pressure in the perineal region during the second stage of labor. C92881 Signs of Impending Birth C92712 NICHD Pregnancy & Childbirth Terminology C92768 Drug Induced Induction of Labor Drug Induced Induction of Labor Using pharmaceutical agents to influence uterine contractions and start labor during the childbirth process. C92814 Induction of Labor C92712 NICHD Pregnancy & Childbirth Terminology C92845 Placental Duncan Mechanism Duncan Mechanism The expulsion of the placenta with presentation of the maternal rough side first, rather than the usual fetal side of the placenta. C92935 Postpartum Process C92712 NICHD Pregnancy & Childbirth Terminology C92769 Duration of Uterine Contraction Duration of Contraction The length of time from the beginning to the end of a single uterine contraction during the labor and childbirth process. C70766 Quantitative Concept C92712 NICHD Pregnancy & Childbirth Terminology C92770 Early Fetal Heart Rate Deceleration Early Deceleration A decrease in the fetal heart rate that occurs in the initial stages of uterine contractions. C92789 Fetal Heart Rate Deceleration C92712 NICHD Pregnancy & Childbirth Terminology C92924 Early Post-Partum Recovery Early Post-Partum Recovery The early stages in the recuperation process of a mother after her pregnancy and delivery. C92936 Post-Partum Recovery C92712 NICHD Pregnancy & Childbirth Terminology C92771 Early Pregnancy Symptom Early Pregnancy Symptoms A characteristic complaint in a fertile woman that is indicative of a pregnancy. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C87167 Eclampsia Eclampsia A potentially life-threatening disorder in pregnant or puerperal women manifested by convulsions in association with hypertension, edema, and/or proteinuria. C27020 Female Reproductive System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C34945 Ectopic Pregnancy Ectopic Pregnancy An abnormal pregnancy in which the egg is implanted anywhere outside the corpus uteri. C92726 Abnormal Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C16541 Embryo Transfer Embryo Transfer Refers to a step in the process of in vitro fertilization (IVF) whereby one or several embryos are removed from an embryo culture and placed into the uterus of the female with the intent to establish a pregnancy. C92930 Conception Method C92712 NICHD Pregnancy & Childbirth Terminology C13229 Embryonic Structure Embryonic Structure A body part, organ or organ component that is formed during the embryonic stage of life of an organism. C34144 Embryonic Structure or System C92712 NICHD Pregnancy & Childbirth Terminology C34144 Embryologic Structure or System Embryonic Structure or System Body tissue, region, surface, cavity, fluid, organ, or collection of organs present in, or associated with, an embryo. C12219 Anatomic Structure or System C92712 NICHD Pregnancy & Childbirth Terminology C92772 Emergency Caesarean Section Emergency Caesarean Section A cesarean section that is unanticipated and carried out during the labor process when it is determined that a vaginal method of delivery would be risky. C46088 Caesarian Section C92712 NICHD Pregnancy & Childbirth Terminology C3014 Endometriosis Endometriosis The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs. C27020 Female Reproductive System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C35435 Enlarging Abdomen Enlarged Abdomen Increasing girth of the mid section of an individual. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C92773 Enlarged Uterus Enlarged Uterus An increase in the overall dimensions or volume of the uterus compared to normal. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C15642 Epidural Block Epidural Block An anesthetic procedure that involves administering pharmaceutical agents into the epidural space of the spinal canal. Frequently administered agents include local anesthetics and analgesics. C64381 Regional Anesthesia Procedure C92712 NICHD Pregnancy & Childbirth Terminology C92774 Episiotomy Episiotomy A surgical widening of the introitus by cutting into the musculature of the maternal perineum with a linear midline or oblique incision so as to facilitate vaginal childbirth. C15384 Surgical Incision C92712 NICHD Pregnancy & Childbirth Terminology C25214 Evaluation Evaluation Procedure Systematic, objective appraisal of the significance, effectiveness, and impact of activities or condition according to specified objectives and criteria. C25218 Intervention or Procedure C92712 NICHD Pregnancy & Childbirth Terminology C81247 Expected Date of Confinement Expected Date of Confinement The projected date of delivery for a pregnant female. C25164 Date C92712 NICHD Pregnancy & Childbirth Terminology C92775 Extended Fetal Attitude Extended Fetal Attitude A position of the fetus during the labor and delivery process where the head is extended back. C92713 Fetal Attitude C92712 NICHD Pregnancy & Childbirth Terminology C92776 External Fetal Rotation External Fetal Rotation External version A manual method of maneuvering the fetus from outside the mother's abdomen to convert a breech into a cephalic presentation. C81179 Delivery Procedure C92712 NICHD Pregnancy & Childbirth Terminology C92778 Face Presentation Face Presentation A fetal position during delivery in which the face of the fetus is first to descend into the birth canal. C92748 Cephalic Presentation C92712 NICHD Pregnancy & Childbirth Terminology C78293 Fallopian Tube Obstruction Fallopian Tube Obstruction Blockage of the normal flow of the contents in the fallopian tube. C27020 Female Reproductive System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C92779 False Labor False Labor A relatively painless, irregular tightening sensation felt by the pregnant mother over the abdomen after the 28th week of pregnancy, that lasts about a minute each time C92904 Uterine Contraction C92712 NICHD Pregnancy & Childbirth Terminology C3036 Fatigue Fatigue That state, following a period of mental or bodily activity, characterized by a lessened capacity for work and reduced efficiency or accomplishment, usually accompanied by a feeling of weariness, sleepiness, or irritability. C92771 Early Pregnancy Symptoms C92712 NICHD Pregnancy & Childbirth Terminology C16579 Fertilization Fertilization The process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronuclei. C92930 Conception Method C92712 NICHD Pregnancy & Childbirth Terminology C92780 Fetal Alcohol Spectrum Disorder Fetal Alcohol Spectrum Disorder A group of disorders caused by a prenatal exposure to maternal consumption of alcohol leading to a range of behavioral, cognitive and neurological deficits in the offspring. It is characterized by physical growth problems, distinct facies, and varying psycho-neurological issues. C97151 Systemic Congenital Disorder C92712 NICHD Pregnancy & Childbirth Terminology C84713 Fetal Alcohol Syndrome Fetal Alcohol Syndrome A syndrome that can develop in infants whose mothers consumed alcohol during pregnancy. Manifestations of this syndrome include low birth weight, failure to thrive, developmental defects, organ dysfunction, mental deficiencies, behavioral problems and poor motor coordination. C92780 Fetal Alcohol Spectrum Disorder C92712 NICHD Pregnancy & Childbirth Terminology C92713 Fetal Attitude Fetal Attitude A position assumed by fetal body parts to one another (head, chest, arms and legs) in relation to the chest. C92711 Fetal Finding C92712 NICHD Pregnancy & Childbirth Terminology C92925 Fetal Biophysical Profile Fetal Biophysical Profile A clinical scoring method to monitor fetal asphyxia using four ultrasonic observations that include fetal breathing, fetal body movements, fetal tone, and amniotic fluid volume. Also included is the non-stress test derived fetal heart rate response to fetal movements. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C92782 Fetal Bradycardia Fetal Bradycardia A decrease in the fetal heart rate below normal baseline values. C92716 Fetal Heart Rate C92712 NICHD Pregnancy & Childbirth Terminology C92783 Fetal Descent Fetal Descent The movement of the fetus led by the presenting part into the maternal pelvic cavity during active labor. C92912 Vaginal Birth Mechanism C92712 NICHD Pregnancy & Childbirth Terminology C50563 Fetal Distress Fetal Distress Symptoms indicative of a state of duress to a fetus while in utero. C81236 Birth Complication C92712 NICHD Pregnancy & Childbirth Terminology C92784 Fetal Engagement Fetal Engagement A position adopted by the fetus during labor when its head moves down into the maternal pelvic cavity. C92912 Vaginal Birth Mechanism C92712 NICHD Pregnancy & Childbirth Terminology C92714 Fetal Examination Fetal Examination A test or diagnostic examination to assess the health status and well being of the fetus. C90341 Pediatric Intervention or Procedure C92712 NICHD Pregnancy & Childbirth Terminology C92785 Fetal Extension Fetal Extension A change in the position of the head of the fetus as it descends through the maternal pelvic cavity during labor and delivery. C92912 Vaginal Birth Mechanism C92712 NICHD Pregnancy & Childbirth Terminology C92786 Fetal Fibronectin Test Fetal Fibronectin Test A laboratory test to detect fetal prematurity by measuring levels of fetal fibronectin from vaginal and cervical secretions. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C92711 Fetal Finding Fetal Finding Any intrauterine symptom or result related to the fetus. C70856 Observational Result C92712 NICHD Pregnancy & Childbirth Terminology C92715 Fetal Heart Finding Fetal Heart Finding An observation of the fetal heart that may or may not be abnormal. C70856 Observational Result C92712 NICHD Pregnancy & Childbirth Terminology C92716 Fetal Heart Rate Fetal Heart Rate The number of fetal cardiac beats per minute. C49677 Heart Rate C92712 NICHD Pregnancy & Childbirth Terminology C92788 Fetal Heart Rate Acceleration Fetal Heart Rate Acceleration An increase in the fetal heart rate above normal baseline values for an extended period. C92715 Fetal Heart Finding C92712 NICHD Pregnancy & Childbirth Terminology C92789 Fetal Heart Rate Deceleration Fetal Heart Rate Deceleration A decrease in the fetal heart rate less than the normal baseline values. C92715 Fetal Heart Finding C92712 NICHD Pregnancy & Childbirth Terminology C92929 Fetal Heart Rate Monitoring Fetal Heart Rate Monitoring The act of observing and recording the fetal heart rate for determining the baseline values and any variations or other abnormal tracings. C92714 Fetal Examination C92712 NICHD Pregnancy & Childbirth Terminology C92790 Fetal Heart Rate Variability Fetal Heart Rate Variability A fetal heart with rate changes from the normal baseline values. C92715 Fetal Heart Finding C92712 NICHD Pregnancy & Childbirth Terminology C92791 Fetal Heart Tone Fetal Heart Tone The sounds of the fetal heart. C92715 Fetal Heart Finding C92712 NICHD Pregnancy & Childbirth Terminology C92792 Fetal Heart Tone Location Fetal Heart Tone Location The site of fetal cardiac sounds that can be distinctly detected in relation to the maternal abdomen. C92715 Fetal Heart Finding C92712 NICHD Pregnancy & Childbirth Terminology C50564 Fetal Hypoxia Fetal Hypoxia Hypoxia in utero, caused by conditions such as inadequate placental function (often abruptio placentae), preeclamptic toxicity, prolapse of the umbilical cord, or complications from anesthetic administration. C81236 Birth Complication C92712 NICHD Pregnancy & Childbirth Terminology C92926 Fetal Position Fetal Position The position of the fetus in the uterus. C92711 Fetal Finding C92712 NICHD Pregnancy & Childbirth Terminology C92927 Fetal Position above Umbilicus Fetal Position above Umbilicus A reference point for the fetal position when the fetal heart rate is detected above the mother's umbilicus. C92926 Fetal Position C92712 NICHD Pregnancy & Childbirth Terminology C92928 Fetal Position below Umbilicus Fetal Position below Umbilicus A reference point for the fetal position when the fetal heart rate is detected below the mother's umbilicus. C92926 Fetal Position C92712 NICHD Pregnancy & Childbirth Terminology C92724 Fetal Presentation Fetal Presentation The first part of the fetus that is visible at the cervical opening during delivery. C92711 Fetal Finding C92712 NICHD Pregnancy & Childbirth Terminology C92794 Fetal Pulse Oximetry Fetal Pulse Oximetry A method to assess fetal oxygenation status during labor and delivery using a noninvasive reflectance pulse oximeter. C92714 Fetal Examination C92712 NICHD Pregnancy & Childbirth Terminology C92795 Fetal Restitution Fetal Restitution The repositioning of the fetal head attitude immediately after delivery, returning to a normal position in alignment with the rest of its body. C92912 Vaginal Birth Mechanism C92712 NICHD Pregnancy & Childbirth Terminology C92717 Fetal Station Fetal Station The relationship of the presenting part of the fetus to the maternal ischial spines during labor and delivery. C92711 Fetal Finding C92712 NICHD Pregnancy & Childbirth Terminology C92796 Fetal Tachycardia Fetal Tachycardia An increase in the fetal heart rate above the normal baseline values. C92716 Fetal Heart Rate C92712 NICHD Pregnancy & Childbirth Terminology C92718 Finding during Childbirth Labor Finding during Childbirth Labor Symptom, signs, test results in a pregnant mother childbirth. C70856 Observational Result C92712 NICHD Pregnancy & Childbirth Terminology C92797 First Movement First Movement An initial set of movements by the fetus that is observed by the pregnant mother. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C92798 First Stage of Labor First Stage of Labor Dilating Stage The stage of the labor and childbirth process when the uterine contractions become strong and regular with cervical effacement and complete dilation of the cervix. C92723 Stages of Labor C92712 NICHD Pregnancy & Childbirth Terminology C92799 First Trimester First Trimester The period of gestation that ranges from the first day of the last menstrual period in a woman up to the 12th week of her pregnancy. C69121 Trimester C92712 NICHD Pregnancy & Childbirth Terminology C92800 Flexed Fetal Attitude Flexed Fetal Attitude A position of the fetus during the labor and delivery process where the fetal chin is in close relation to its chest; other joints are also in a flexed position. This prepares the fetus to present the smallest diameter for passage through the maternal pelvis. C92713 Fetal Attitude C92712 NICHD Pregnancy & Childbirth Terminology C92787 Fetal Flexion Flexion A cardinal movement in labor when the head of the fetus folds towards its chest to assume the smallest anero-posterior diameter for the presenting part during delivery. C92912 Vaginal Birth Mechanism C92712 NICHD Pregnancy & Childbirth Terminology C92801 Food Craving Food Craving An abnormal desire for eating certain foods. C92771 Early Pregnancy Symptoms C92712 NICHD Pregnancy & Childbirth Terminology C81248 Forceps Delivery Forceps Delivery The method referring to the delivery of a fetus through the vaginal canal with assistance of obstetrical forceps. C81301 Vaginal Assisted Delivery C92712 NICHD Pregnancy & Childbirth Terminology C92802 Fourth Stage of Labor Fourth Stage of Labor Recovery Stage A stage during labor and childbirth that starts with the delivery of the placenta and lasts about two hours after delivering the baby. C92723 Stages of Labor C92712 NICHD Pregnancy & Childbirth Terminology C64380 General Anesthesia Procedure General Anesthesia Procedure Actions that render a patient unconscious for the purpose of performing a diagnostic or interventional procedure. C15181 Anesthesia Procedure C92712 NICHD Pregnancy & Childbirth Terminology C92804 Gestational Gestational The period of fetal development in the uterus from the start of conception until its birth. C92858 Pregnancy Time Period C92712 NICHD Pregnancy & Childbirth Terminology C34942 Gestational Diabetes Mellitus Gestational Diabetes Diabetes that develops during pregnancy. It usually resolves after delivery. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C92805 Group B Streptococcus Screening Group B Streptococcus Screening Screening with a swab from the vaginal and rectal areas in late pregnancy to test for the presence of Group B streptococcal infection. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C15332 Gynecological Surgical Procedure Gynecologic Surgical Procedure Surgery performed on the female reproductive system. C15329 Surgical Procedure C92712 NICHD Pregnancy & Childbirth Terminology C16205 Healthcare Activity Healthcare Activity The actions of prevention, treatment, and management of illness and the preservation of mental and physical well-being through the services offered by the medical and allied health professions. C90259 NICHD Pediatric Terminology C92712 NICHD Pregnancy & Childbirth Terminology C84750 HELLP Syndrome HELLP Syndrome A life-threatening complication of pregnancy usually occurring in women with preeclampsia or eclampsia. It is characterized by hemolytic anemia, elevated liver enzymes, and low platelet count. Signs and symptoms include headaches, nausea, vomiting, blurred vision, and upper abdominal pain. It may lead to diffuse intravascular coagulation and acute renal failure. C85021 Preeclampsia C92712 NICHD Pregnancy & Childbirth Terminology C64848 Hemoglobin Measurement Hemoglobin Measurement A quantitative measurement of the amount of hemoglobin present in a sample. C25294 Laboratory Procedure C92712 NICHD Pregnancy & Childbirth Terminology C34376 Hemolytic Anemia Hemolytic Anemia Anemia resulting from the premature destruction of the peripheral blood red cells. It may be congenital or it may be caused by infections, medications, or malignancies. C26323 Hematological Disorder C92712 NICHD Pregnancy & Childbirth Terminology C92806 Hepatitis B Screening Hepatitis B Screening A test performed to determine the presence or absence of hepatitis B surface antigen. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C50583 Herpes Herpes Any inflammatory skin disease caused by a herpesvirus and characterized by the formation of small vesicles in clusters. C3439 Viral Disease C92712 NICHD Pregnancy & Childbirth Terminology C92807 High Risk Pregnancy High Risk Pregnancy A fetal/maternal condition that is risky and portends complications for the mother and/or fetus, when compared to a normal pregnancy. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C92859 Prenatal HIV Screening HIV Screening Testing of a pregnant mother for antibodies to the human immunodeficiency virus (HIV) in early pregnancy. Results permit management to reduce the chances of maternal transmission of HIV to the fetus. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C92808 Hormonal Contraception Hormonal Method The birth control method that utilizes external source of sex hormones to prevent pregnancy by interfering with the ovulation, fertilization or implantation of the fertilized egg in the uterus. C37932 Contraception C92712 NICHD Pregnancy & Childbirth Terminology C92809 Hormone Imbalance Hormone Imbalance An abnormal finding indicating that the level of a particular hormone is not within the expected normal values. C3009 Endocrine System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C75387 Human Chorionic Gonadotropin Measurement Human Chorionic Gonadotropin Measurement A laboratory test to detect the amount of human chorionic gonadotropin in a biospecimen. C92949 Pregnancy Test C92712 NICHD Pregnancy & Childbirth Terminology C87084 Hyperemesis Gravidarum Hyperemesis Gravidarum Severe, intractable vomiting during pregnancy (usually the first trimester) accompanied by dehydration, weight loss, and electrolyte imbalances. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C92810 Hypnobirthing Hypnobirthing An unique natural method of childbirth that is supported by a relaxing self-hypnosis method. C92738 Assisted Labor C92712 NICHD Pregnancy & Childbirth Terminology C15256 Hysterectomy Hysterectomy A surgical procedure to remove the uterine body (partial hysterectomy) or the uterine body and cervix (total hysterectomy). -- 2004 C15332 Gynecologic Surgical Procedure C92712 NICHD Pregnancy & Childbirth Terminology C92811 Hysterotomy Hysterotomy A surgical incision made on the uterus to access the uterine cavity. C15384 Surgical Incision C92712 NICHD Pregnancy & Childbirth Terminology C92812 Hysterotomy Abortion Hysterotomy Abortion A type of abortion where the product of conception is accessed through a surgical incision on the corpus uteri intended to terminate the pregnancy. C92954 Induced Abortion C92712 NICHD Pregnancy & Childbirth Terminology C15258 Immunization Immunization Inoculating an individual with either killed or live agents to prevent contraction of a disease. C15843 Preventive Intervention C92712 NICHD Pregnancy & Childbirth Terminology C92813 Impending Labor Impending Labor The period of time prior to the beginning of childbirth labor; common signs and symptoms include nesting, anxiety, excitement, loss of mucous plug, increased urinary frequency and loose bowel movements. C21173 Reproductive Process C92712 NICHD Pregnancy & Childbirth Terminology C16580 in vitro Fertilization In Vitro Fertilization Fertilization of an ovum outside of the body. C92930 Conception Method C92712 NICHD Pregnancy & Childbirth Terminology C26906 Urinary Frequency Increased Frequency of Urination Urination at short intervals; it may result from increased urine formation, decreased bladder capacity, or lower urinary tract irritation. C92771 Early Pregnancy Symptoms C92712 NICHD Pregnancy & Childbirth Terminology C92954 Induced Abortion Procedure Induced Abortion A surgical or medical procedure that terminates a pregnancy by removing the fetus. C92894 Therapeutic Abortion C92712 NICHD Pregnancy & Childbirth Terminology C92814 Induction of Labor Induction of Labor The administration of pharmaceutical agents to promote the start of labor and childbirth process. C92738 Assisted Labor C92712 NICHD Pregnancy & Childbirth Terminology C3836 Infertility Infertility Inability to conceive for at least one year after trying and having unprotected sex. Causes of female infertility include endometriosis, fallopian tubes obstruction, and polycystic ovary syndrome. Causes of male infertility include abnormal sperm production or function, blockage of the epididymis, blockage of the ejaculatory ducts, hypospadias, exposure to pesticides, and health related issues. C27020 Female Reproductive System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C92815 Intense Uterine Contraction Intensified Contraction A powerful, temporary tensing of the uterine muscles that is stronger than previously felt movements. C92904 Uterine Contraction C92712 NICHD Pregnancy & Childbirth Terminology C92816 Intermittent Fetal Heart Rate Deceleration Intermittent Deceleration An infrequently repeated decrease in the fetal heart rate that occurs in conjunction with a uterine contraction. C92789 Fetal Heart Rate Deceleration C92712 NICHD Pregnancy & Childbirth Terminology C92817 Internal Fetal Rotation Internal Fetal Rotation A finding during labor, in which the occiput rotates anteriorly and the head of the fetus assumes an oblique orientation while the fetus descends through the maternal pelvis. C92718 Finding during Childbirth Labor C92712 NICHD Pregnancy & Childbirth Terminology C42771 Intrauterine Device Intra Uterine Device A device usually made of plastic or metal, inserted into the uterus to prevent conception. IUCD can be a coil, loop, triangle, or T in shape; its material can be impregnated with a pharmaceutical agent. The primary action of all IUCDs is the induction of a foreign-body reaction within the endometrium. This sterile inflammatory process is toxic to gametes, primarily spermatozoa, and effectively prevents viable sperm from passing into the fallopian tubes. The copper-bearing device has an independent toxic effect on spermatozoa. The progestin-releasing devices produce changes in endometrial architecture and function that reduce the potential for implantation of a fertilized egg. The progestin effect on the cervical mucus also reduces the penetrability of sperm. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C92818 Intrapartum Intrapartum The period of time during labor and delivery. C92858 Pregnancy Time Period C92712 NICHD Pregnancy & Childbirth Terminology C92922 Cardiotocography Intrapartum Cardiotocography Electronic fetal monitoring|continuous cardiotocography (CTG)|intrapartum CTG The monitoring of both maternal uterine contractions and fetal heart rate during the process of labor and delivery. C92714 Fetal Examination C92712 NICHD Pregnancy & Childbirth Terminology C92819 Intrapartum Process Intrapartum Process The process that occurs during labor and delivery. C92934 Labor and Delivery Process C92712 NICHD Pregnancy & Childbirth Terminology C92820 Intrauterine Cordocentesis Intrauterine Cordocentesis Fetal Blood Sampling|Percutaneous Umbilical Blood Sampling (PUBS)|Umbilical Vein Sampling The retrieval of blood sample from the umbilical cord while the fetus is in utero. C16847 Technique C92712 NICHD Pregnancy & Childbirth Terminology C80083 Fetal Growth Retardation Intrauterine Growth Retardation Fetal Growth Restriction|Fetal Growth Retardation|IUGR|Intrauterine Growth Restriction Inhibition of fetal growth resulting in the inability of the fetus to achieve its potential size. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C92743 Birthing Labor Labor The processes an individual engages in when she attempts to gives birth. C92819 Intrapartum Process C92712 NICHD Pregnancy & Childbirth Terminology C92934 Parturition Labor and Delivery Process The process by which a mammal gives birth. C21173 Reproductive Process C92712 NICHD Pregnancy & Childbirth Terminology C92821 Labor Pain Labor Pain The discomfort that is experienced by the pregnant mother during the childbirth process as she attempts to give birth. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C15266 Laparotomy Laparotomy Creation of a surgical opening into the abdominal cavity. C15384 Surgical Incision C92712 NICHD Pregnancy & Childbirth Terminology C87092 Large for Gestational Age Large for Gestational Age A fetus or infant who is larger than expected for the age or gender, or who has a birthweight greater than the 90th percentile. C25447 Characteristic C92712 NICHD Pregnancy & Childbirth Terminology C81257 Last Menstrual Period Last Menstrual Period The first day of the female's last menstrual cycle. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C92822 Late Fetal Heart Rate Deceleration Late Deceleration A decrease in the fetal heart rate that occurs gradually after the peak in uterine contraction. C92789 Fetal Heart Rate Deceleration C92712 NICHD Pregnancy & Childbirth Terminology C92823 Late Pregnancy Bleeding Late Pregnancy Bleeding An abnormal bleeding through the vagina that occurs during the last trimester of pregnancy. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C92941 Latent Phase of Labor Latent Phase of Labor The period during the first stage of labor and childbirth that precedes the active phase of labor. C92798 First Stage of Labor C92712 NICHD Pregnancy & Childbirth Terminology C92824 Leakage of Amniotic Fluid Leakage of Amniotic Fluid The discharge of amniotic fluid vaginally due to a tear or rupture in the amniotic membrane. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C92825 Left Occiput Anterior Presentation Left Occiput Anterior A fetal position during delivery in which the head of the fetus is in the birth canal facing the area between the right hip and the spine of the mother. C92732 Anterior Occiput C92712 NICHD Pregnancy & Childbirth Terminology C81260 Local Anesthesia Procedure Local Anesthesia Procedure The temporary suppression of sensation at a specific region of the body by pharmacological intervention. This type of anesthesia does not induce unconsciousness in the patient. C15181 Anesthesia Procedure C92712 NICHD Pregnancy & Childbirth Terminology C78742 Lochia Lochial Flow Vaginal discharge occurring during the post-partum period. It consists of a mixture of blood, mucus, and placental remnants. C92935 Postpartum Process C92712 NICHD Pregnancy & Childbirth Terminology C92826 Longitudinal Fetal Presentation Longitudinal Fetal Presentation A type of fetal presentation where the fetal spine is aligned along the longitudinal axis of the uterus and descends into the birth canal during delivery. C92724 Fetal Presentation C92712 NICHD Pregnancy & Childbirth Terminology C34724 Low Birth Weight Low Birth Weight Refers to a fetus or infant who is smaller than expected for the age or gender, or who has a birthweight less than the 10th percentile. C76325 Birth Weight C92712 NICHD Pregnancy & Childbirth Terminology C92827 Lower Uterine Segment Incision Lower Uterine Segment Incision A surgical incision line on the uterus that is transversely cut in relation to the lower uterine segment. C15384 Surgical Incision C92712 NICHD Pregnancy & Childbirth Terminology C92793 Fetal Malpresentation Malpresentation of Fetus An abnormal position assumed by the fetus in the birth canal during the childbirth process. C81236 Birth Complication C92712 NICHD Pregnancy & Childbirth Terminology C92828 Maternal Fever Maternal Fever The elevation of body temperature in a pregnant mother above 38 degrees C or more than 101 degrees F, and may be indicative of an infection. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C92829 Maternal Hypotension Maternal Hypotension A decrease in the systolic blood pressure in a pregnant mother for values that are less than 25% of her normal blood pressure levels or arbitrarily, one that is less than 100 mm Hg during pregnancy. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C97176 Maternal Obesity Maternal Obesity Obesity in a female who has a child. C26836 Nutritional Disorder C92712 NICHD Pregnancy & Childbirth Terminology C81182 Measurement Device Measurement Device Any device used to determine the dimension of an object. C62103 Device C92712 NICHD Pregnancy & Childbirth Terminology C78743 Meconium Meconium The newborn's first intestinal discharge. It is a dark-green, thick substance composed of mucus, intestinal secretions, hair, and intestinal mucosa cells. C13236 Biological Substance C92712 NICHD Pregnancy & Childbirth Terminology C87093 Meconium Aspiration Syndrome Meconium Aspiration Syndrome A serious condition in which a newborn breathes a mixture of meconium (the first intestinal discharge) and amniotic fluid into the lungs around the time of delivery. Meconium aspiration syndrome occurs in 5-10 percent of births and typically occurs when the infant is stressed, as when the infant is past its due date. C97173 Congenital Abnormality of the Respiratory System C92712 NICHD Pregnancy & Childbirth Terminology C3231 Menopause Menopause The permanent cessation of menses, usually defined by 6 to 12 months of amenorrhea in a woman over 45 years of age. C19988 Organismal Process C92712 NICHD Pregnancy & Childbirth Terminology C92830 Midline Longitudinal Uterine Incision Midline Longitudinal Incision A surgical incision line that extends in a midline longitudinal axis of the uterus. C15384 Surgical Incision C92712 NICHD Pregnancy & Childbirth Terminology C92831 Mild Uterine Contraction Mild Uterine Contractions An uterine contraction that is barely felt. C92904 Uterine Contraction C92712 NICHD Pregnancy & Childbirth Terminology C92832 Missed Menstrual Period Missed Period The absence of a menstrual period based on the expected start date of the menstrual cycle. C92771 Early Pregnancy Symptoms C92712 NICHD Pregnancy & Childbirth Terminology C92833 Montgomery Tubercle Montgomery's Tubercles A group of small sebaceous glands that secrete into the areolae of the mother's breast to lubricate the nipple during breastfeeding. C92771 Early Pregnancy Symptoms C92712 NICHD Pregnancy & Childbirth Terminology C92937 Pregnancy Mood Swing Mood Swing The fluctuations in the mental and emotional state of an individual during pregnancy. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C92834 Morning Sickness Morning Sickness The nausea and vomiting that accompanies early pregnancy. C92771 Early Pregnancy Symptoms C92712 NICHD Pregnancy & Childbirth Terminology C34213 Mucous Connective Tissue Mucous Connective Tissue Wharton's Jelly A gelatinous type of connective tissue that is found in the umbilical cord. C13236 Biological Substance C92712 NICHD Pregnancy & Childbirth Terminology C92752 Cervical Mucus Plug Mucus Plug A mucus plug situated in the maternal cervical os during pregnancy that prevents entry of bacteria into the uterus. C13236 Biological Substance C92712 NICHD Pregnancy & Childbirth Terminology C81271 Multiple Birth Multiple Birth A single birthing event that produces two or more offspring. C90491 Pregnancy Outcome C92712 NICHD Pregnancy & Childbirth Terminology C87097 Multiple Gestation Multiple Gestation A pregnancy involving twins or higher-order multiple fetuses (e.g., triplets, quadruplets). C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C92931 Multiple Pregnancy Multiple Pregnancy A gestation with more than one fertilized egg implanted as a viable fetus in the uterus. C92933 Normal Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C92932 Natural Birth Natural Birth The process of giving birth vaginally without any surgical intervention. C90491 Pregnancy Outcome C92712 NICHD Pregnancy & Childbirth Terminology C84915 Necrotizing Enterocolitis Necrotizing Enterocolitis A serious, life-threatening disorder characterized by necrotic changes affecting portions of the small and large intestine. It is usually seen in neonates, particularly premature infants. Signs and symptoms include abdominal distention and tenderness, intestinal bleeding and ileus. It may lead to cardiovascular collapse and shock. C97171 Congenital Abnormality of the Digestive System C92712 NICHD Pregnancy & Childbirth Terminology C35450 Negative Pregnancy Test Negative Pregnancy Test A finding which indicates an individual is not pregnant. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C27560 Neonatal Respiratory Distress Syndrome Neonatal Respiratory Distress Syndrome A condition of the newborn marked by dyspnea with cyanosis, most frequently occurring in premature infants, children of diabetic mothers and infants delivered by cesarean section, and sometimes with no predisposing cause. C97173 Congenital Abnormality of the Respiratory System C92712 NICHD Pregnancy & Childbirth Terminology C92835 Neutral Fetal Attitude Neutral Fetal Attitude A position of the fetus during the labor and delivery process where the fetal chin is mildly flexed but with a forward facing head. C92713 Fetal Attitude C92712 NICHD Pregnancy & Childbirth Terminology C92836 Obstetric Non-Stress Test Non-Stress Test A non-invasive test usually done during the third trimester to check for fetal well being. It is performed using an external fetal heart rate monitor to assess the fetal heart rate response to fetal movements. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C92933 Normal Pregnancy Normal Pregnancy A pregnancy that is normal for both the mother and the fetus. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C94835 Normal Spontaneous Vaginal Delivery Normal Spontaneous Vaginal Delivery Normal Delivery A process of birthing whereby the fetus is born unaided by medical inducements or surgical intervention and without complication. C81303 Vaginal Delivery C92712 NICHD Pregnancy & Childbirth Terminology C92891 Subdermal Birth Control Implant Norplant Subdermal Birth Control Implant A subdermal implant incorporating silastic tubing containing levonorgestrel designed to administer a continuous dose of progestins for pregnancy contraception. C92759 Contraceptive Implant C92712 NICHD Pregnancy & Childbirth Terminology C92837 Nuchal Translucency Screen Nuchal Translucency Screen nuchal fold scan An ultrasonic examination of the fetus to confirm gestational age by assessing and measuring for the clear space at the back of the fetal neck using external calipers. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C92838 Oblique Fetal Presentation Oblique Fetal Presentation A fetal position during delivery in which the spine of the fetus is not aligned with the mother's resulting in the descent into the birth canal in an oblique position. C92724 Fetal Presentation C92712 NICHD Pregnancy & Childbirth Terminology C92839 Oligohydramnios Oligohydramnios A lower than normal volume of amniotic fluid observed by ultrasound during pregnancy. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C15291 Oophorectomy Oophorectomy Partial or complete removal of one or both of the ovaries. C15332 Gynecologic Surgical Procedure C92712 NICHD Pregnancy & Childbirth Terminology C389 Oral Contraceptive Oral Contraceptive Pill An agent taken orally to prevent conception. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C92945 Ovarian Pregnancy Ovarian Pregnancy An ectopic pregnancy of unknown etiology that occurs in the ovary instead of the uterine corpus. It may result in severe intra-abdominal bleeding. C34945 Ectopic Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C66849 Ovulation Ovulation Release of Egg The discharge of a secondary oocyte from a vesicular follicle of the ovary. C21173 Reproductive Process C92712 NICHD Pregnancy & Childbirth Terminology C2283 Oxytocin Oxytocin Oxytocin (125 aa, ~13kDa) is encoded by the human OXT gene. This protein plays a role in smooth muscle contraction in both the mammary gland and uterus. Oxytocin also is involved in maternal-newborn bonding, cognition and many other psychological and physiological processes. C13236 Biological Substance C92712 NICHD Pregnancy & Childbirth Terminology C17348 Papanicolaou Smear Procedure Pap Smear A sample of secretions and superficial cells of the body of uterus, cervix, and ovaries; examined with a microscope to detect any abnormal cells. C15843 Preventive Intervention C92712 NICHD Pregnancy & Childbirth Terminology C92840 Passing of Mucus Plug Passing of Mucus Plug A discharge of the mucus plug from the cervical os during cervical dilation in preparation for the labor and delivery of the baby. C92819 Intrapartum Process C92712 NICHD Pregnancy & Childbirth Terminology C92841 Perinatal Death Perinatal Death The death of an infant before birth after 28 weeks of gestation or shortly after birth. C90491 Pregnancy Outcome C92712 NICHD Pregnancy & Childbirth Terminology C92842 Persistent Fetal Bradycardia Persistent Fetal Bradycardia A decrease in the fetal heart beat rate below 110 per minute or below the normal baseline value expected for the particular fetal age for a period of more than 10 minutes. C92782 Fetal Bradycardia C92712 NICHD Pregnancy & Childbirth Terminology C92843 Persistent Fetal Tachycardia Persistent Fetal Tachycardia An increase in the fetal heart rate above the expected normal baseline values for an extended period. C92796 Fetal Tachycardia C92712 NICHD Pregnancy & Childbirth Terminology C92844 Physiologic Lightening Physiologic Lightening A physical feeling of being able to breathe better during late trimester of pregnancy when the baby starts to descend lower into the pelvic cavity. C92819 Intrapartum Process C92712 NICHD Pregnancy & Childbirth Terminology C26858 Placenta Previa Placenta Previa A condition in which the placenta is implanted in the lower part of the uterus. --2003 C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C26685 Premature Separation of Placenta Placental Abruption The separation of the placenta from the maternal uterine attachment when it occurs after the twentieth week of the pregnancy. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C92854 Postpartum Placental Separation Placental Separation A process in childbirth in which the placenta separates from its uterine lining, after the delivery of the baby. C92935 Postpartum Process C92712 NICHD Pregnancy & Childbirth Terminology C92847 Polycystic Ovary Syndrome Polycystic Ovary Syndrome A disorder that manifests as multiple cysts on the ovaries. It results in hormonal imbalances and leads to irregular and abnormal menstrual periods, excess growth of hair, acne eruptions and obesity. C3009 Endocrine System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C92848 Polyhydramnios Polyhydramnios An excess quantity of amniotic fluid in the amniotic sac as compared to normal values. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C92849 Positive Pregnancy Test Positive Pregnancy Test A test result indicating the presence of hormones (HCG) in the blood or urine of a woman that confirm pregnancy . C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C92850 Posterior Occiput Presentation Posterior Occiput A fetal position during delivery in which the head of the fetus is facing the mother's abdomen. C92926 Fetal Position C92712 NICHD Pregnancy & Childbirth Terminology C92851 Postpartum Postpartum The period of time immediately after labor and delivery. C92858 Pregnancy Time Period C92712 NICHD Pregnancy & Childbirth Terminology C92852 Postpartum Depression Postpartum Depression A type of clinical depression that occurs after childbirth. C2982 Depression C92712 NICHD Pregnancy & Childbirth Terminology C92853 Postpartum Hemorrhage Postpartum Hemorrhage Hemorrhage defined as a blood loss in excess of 500 mL after vaginal delivery or more than 1000 mL after a cesarean delivery. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C92935 Postpartum Process Postpartum Process The recovery and readjustment process in a mother after pregnancy and delivery. C92934 Labor and Delivery Process C92712 NICHD Pregnancy & Childbirth Terminology C92936 Postpartum Recovery Post-Partum Recovery The healing and recuperation of the mother including physiological readjustment after pregnancy and delivery of the baby. C92935 Postpartum Process C92712 NICHD Pregnancy & Childbirth Terminology C85021 Preeclampsia Preeclampsia A pregnancy-related disorder characterized by an increase in the blood pressure after the twentieth week of gestation, and by the presence of proteinuria. It may appear up to six weeks post-partum. It may lead to eclampsia with development of tonic-clonic seizures. C4371 Pregnancy Induced Hypertension C92712 NICHD Pregnancy & Childbirth Terminology C25742 Pregnancy Pregnancy The state or condition of having a developing embryo or fetus in the body (uterus), after union of an ovum and spermatozoon, during the period from conception to birth. C21173 Reproductive Process C92712 NICHD Pregnancy & Childbirth Terminology C91825 Pappalysin-1 Pregnancy Associated Plasma Protein A Pappalysin-1 (1627 aa, ~181 kDa) is encoded by the human PAPPA gene. This protein is involved in the modulation of proteolysis. C92745 Blood Test for Protein Level C92712 NICHD Pregnancy & Childbirth Terminology C92720 Pregnancy Finding Pregnancy Finding Symptoms, signs, diagnostic examinations or a test results in a pregnant mother. C36284 Reproductive System Finding C92712 NICHD Pregnancy & Childbirth Terminology C4371 Pregnancy Associated Hypertension Pregnancy Induced Hypertension The most common complication of pregnancy. It may appear as chronic hypertension or preeclampsia. It may cause brain hemorrhage, pulmonary edema, abruptio placentae, gestational diabetes mellitus, renal failure, premature delivery and fetal growth abnormalities. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C90491 Pregnancy Outcome Pregnancy Outcome Findings observed at the end of a pregnancy. C36284 Reproductive System Finding C92712 NICHD Pregnancy & Childbirth Terminology C92949 Pregnancy Test Pregnancy Test Any examination performed to assess if a female is gravid. C18020 Diagnostic Procedure C92712 NICHD Pregnancy & Childbirth Terminology C92858 Pregnancy Time Period Pregnancy Time Period The duration of pregnancy from conception to childbirth. C21514 Temporal Qualifier C92712 NICHD Pregnancy & Childbirth Terminology C50917 Premature Labor Premature Labor Ouster of a viable infant before the normal end of gestation, commonly defined as interruption of pregnancy between the twentieth-thirty seventh completed weeks after the onset of the last menstrual cycle. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C87113 Premature Rupture of Membrane Premature Rupture of Membranes PROM The condition when a patient who is beyond 37 weeks gestation presents with rupture of membranes prior to the onset of labor. Rupture of membranes is diagnosed by speculum vaginal examination of the cervix and vaginal cavity, which will show pooling of fluid in the vagina or leakage of fluid from the cervix. Preterm PROM (known as PPROM) refers to a patient who has not yet reached 37 weeks gestation and presents with rupture of membranes. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C81318 Prenatal Prenatal The time period after impregnation and before birth. C92858 Pregnancy Time Period C92712 NICHD Pregnancy & Childbirth Terminology C92860 Prenatal Vitamin Prenatal Vitamins A vitamin enriched supplement containing higher doses for specific nutrients such as folic acid, intended for women before, during and after pregnancy and also during their lactating phase. C45306 Substance C92712 NICHD Pregnancy & Childbirth Terminology C92861 Preterm Birth Preterm Birth The birth of an infant of less than 37 weeks for the gestational age. C90491 Pregnancy Outcome C92712 NICHD Pregnancy & Childbirth Terminology C92862 Preterm Premature Rupture of Membrane Preterm Premature Rupture of Membrane PPROM An early rupture of the amniotic membranes during pregnancy and one that precedes 37 weeks of gestation. C87113 Premature Rupture of Membranes C92712 NICHD Pregnancy & Childbirth Terminology C778 Prolactin Prolactin Human prolactin (227 aa, 26 kDa precursor) is encoded by the human prolactin (PIT1) gene. This secreted lactogenic glycoprotein is expressed in both anterior pituitary lactotropes and the decidual endometrium. It acts primarily on the mammary gland and, in synergy with estrogen, induces progesterone release by corpus luteum cells to render the uterine mucosa suitable for implantation. C13236 Biological Substance C92712 NICHD Pregnancy & Childbirth Terminology C92863 Prolonged Fetal Heart Rate Acceleration Prolonged Acceleration An abrupt and extended increase in the fetal heart rate during labor contractions. C92788 Fetal Heart Rate Acceleration C92712 NICHD Pregnancy & Childbirth Terminology C92864 Prolonged Fetal Heart Rate Deceleration Prolonged Deceleration An extended decrease in the fetal heart rate compared to the normal baseline values. C92789 Fetal Heart Rate Deceleration C92712 NICHD Pregnancy & Childbirth Terminology C34965 Pyelonephritis Pyelonephritis An acute or chronic inflammatory process affecting the kidney. It is caused by bacteria and in most cases it is the result of a urinary tract infection. Signs and symptoms include fever, chills, flank pain, painful and frequent urination, cloudy or bloody urine, and confusion. C2890 Bacterial Disease C92712 NICHD Pregnancy & Childbirth Terminology C92865 Quad Screen Quad Screen A screening measurement in which the maternal blood levels of alpha-fetoprotein, unconjugated estriol, human chorionic gonadotrophin and Inhibin A are calculated. These are then evaluated in relation to the mother's age, weight and fetal gestational age. C92803 Screening for Genetic Defect C92712 NICHD Pregnancy & Childbirth Terminology C92866 Recurrent Fetal Heart Rate Deceleration Recurrent Deceleration A frequently repeated decrease in the fetal heart rate that occurs in conjunction with a uterine contraction; this happens with the majority of heartbeats. C92789 Fetal Heart Rate Deceleration C92712 NICHD Pregnancy & Childbirth Terminology C64381 Regional Anesthesia Procedure Regional Anesthesia Procedure The administration of pharmaceutical agents intended to produce loss of sensation in a particular anatomical region. C15181 Anesthesia Procedure C92712 NICHD Pregnancy & Childbirth Terminology C92867 Regular Uterine Contraction Regular Contraction A consistent rhythmic pattern of uterine muscle tightening that occurs at regular intervals for the same duration of time. C92904 Uterine Contraction C92712 NICHD Pregnancy & Childbirth Terminology C92868 Regularity of Uterine Contraction Regularity of Uterine Contraction The nature and pattern of occurrence for the uterine contractions during labor. C70766 Quantitative Concept C92712 NICHD Pregnancy & Childbirth Terminology C21173 Reproductive Process Reproductive Process A Reproductive System Process involves a function of cellular, cell, or tissue components of the organ system involved in generation of offspring that includes the ovaries, fallopian tubes, uterus, cervix, and vagina in women or the prostate, testes, and penis in men. C19988 Organismal Process C92712 NICHD Pregnancy & Childbirth Terminology C36284 Reproductive System Finding Reproductive System Finding Symptoms, physical examination results, and/or laboratory test results related to the reproductive system. C70856 Observational Result C92712 NICHD Pregnancy & Childbirth Terminology C27561 Respiratory Distress Syndrome Respiratory Distress Syndrome A group of conditions characterized by failure of normal respiration caused by lack of lung surfactant. C26871 Respiratory System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C92948 Rh Factor Measurement Rh factor Measurement An immunology test to measure for the presence of the Rh factor antigen in blood. C47868 Blood Test C92712 NICHD Pregnancy & Childbirth Terminology C92947 Rh Immune Globulin Administration Rh Immune Globulin Administration Rho(D) Immune Globulin Administration The administration of Rh Immune Globulin to a pregnant mother to ameliorate the effects of conflicting Rh factors during pregnancy. C15843 Preventive Intervention C92712 NICHD Pregnancy & Childbirth Terminology C84504 Rh Incompatibility Rh Incompatibility A complication during pregnancy; it occurs when the mother is Rh-negative and the infant is Rh-positive. The mother's body develops antibodies against the fetal red blood cells leading to their destruction. This complication generally does not affect first-born Rh-positive babies. Rh-positive newborn babies from subsequent pregnancies develop complications of Rh incompatibility which include hemolysis, jaundice, enlarged liver and spleen, petechiae, hypotonia, neurologic damage, and heart problems. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C92871 Right Occiput Anterior Presentation Right Occiput Anterior ROA A fetal position during delivery in which the fetus is in the birth canal and the back of the head is oriented towards the maternal right thigh region. C92732 Anterior Occiput C92712 NICHD Pregnancy & Childbirth Terminology C69284 R-R Interval R-R Wave Period The time measurement between the R wave (ventricular depolarization) of successive heartbeats as measured in milliseconds. C92790 Fetal Heart Rate Variability C92712 NICHD Pregnancy & Childbirth Terminology C92872 Rubella Immunization Rubella Immunization The administration of a live attenuated viral vaccine to prevent rubella infection. C15258 Immunization C92712 NICHD Pregnancy & Childbirth Terminology C85051 Rubella Infection Rubella Infection German Measles A viral infection caused by the rubella virus. It is initially manifested with flu-like symptoms that last one or two days, followed by the development of a characteristic red rash which lasts from one to five days. The rash first appears in the neck and face. It subsequently spreads to the rest of the body. C3439 Viral Disease C92712 NICHD Pregnancy & Childbirth Terminology C92874 Rupture of Membrane Rupture of Membrane amniorrhexis|breaking water Breaking or tearing of the amniotic membranes during childbirth leading to the leakage of amniotic fluid and the progression of labor. C92819 Intrapartum Process C92712 NICHD Pregnancy & Childbirth Terminology C92846 Placental Schultze Mechanism Schultze Mechanism The separation of the placenta from the uterine wall during labor; it begins at the placental center and leads to an expulsion of the placenta after delivery of the baby. C92766 Delivery of Placenta C92712 NICHD Pregnancy & Childbirth Terminology C92916 Varicella Zoster Virus Screening Screening for Chickenpox A test to determine if an individual has antibodies to the varicella zoster virus. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C92803 Genetic Screening Screening for Genetic Defect Testing to determine if there is a predisposition or indication of a possible genetic or a chromosomal abnormality. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C92873 Rubella Screening Screening for Rubella A test during pregnancy to determine maternal exposure to the rubella virus that could lead to pregnancy complications or congenital rubella syndrome in the newborn. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C92721 Pregnancy Related Screening Screening or Clinical Tests during Pregnancy A group of tests performed during pregnancy to assess fetal health and to detect for genetic abnormalities and various disorders. C15843 Preventive Intervention C92712 NICHD Pregnancy & Childbirth Terminology C92875 Second Stage of Labor Second Stage of Labor Birthing Stage A stage during labor and childbirth when the cervix is effaced totally and remains dilated until the birth of the baby. C92723 Stages of Labor C92712 NICHD Pregnancy & Childbirth Terminology C92876 Second Trimester Second Trimester The period of gestation that ranges from the 13th to the 27th week of pregnancy. C69121 Trimester C92712 NICHD Pregnancy & Childbirth Terminology C92877 Sexual Abstinence Sexual Abstinence Prevention of contraception by not engaging in sexual intercourse. C37932 Contraception C92712 NICHD Pregnancy & Childbirth Terminology C92878 Sexually Transmitted Disease Screening Sexually Transmitted Disease Screening A test to detect the presence of a sexually transmissible disease such as HIV, chlamydia, syphilis, gonorrhea, hepatitis B or hepatitis C. C15843 Preventive Intervention C92712 NICHD Pregnancy & Childbirth Terminology C92879 Short-Term Fetal Heart Rate Variability Short-Term Variability A non-sustained irregular fetal heart rate in comparison to normal baseline values. C92790 Fetal Heart Rate Variability C92712 NICHD Pregnancy & Childbirth Terminology C81290 Shoulder Dystocia Shoulder Dystocia Abnormal labor or childbirth due to fetal shoulder obstruction in the vaginal canal. C81236 Birth Complication C92712 NICHD Pregnancy & Childbirth Terminology C92880 Shoulder Presentation Shoulder Presentation A fetal position during delivery in which the shoulder descends into the birth canal first. C92793 Malpresentation of Fetus C92712 NICHD Pregnancy & Childbirth Terminology C92881 Signs of Impending Birth Signs of Impending Birth The indicating characteristics in a pregnant mother who is in the process of labor and delivery of a fetus; common signs and symptoms include nesting, anxiety, excitement, loss of mucous plug, increased urinary frequency and loose bowel movements. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C92882 Sinciput Presentation Sinciput A fetal position during delivery in which the frontal part of the skull including forehead and the top of the head is first to descend into the birth canal. C92926 Fetal Position C92712 NICHD Pregnancy & Childbirth Terminology C35024 Sinusitis Sinus Infection An acute or chronic infectious process affecting the mucous membranes of the paranasal sinuses. C26726 Infectious Disease C26871 Respiratory System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C92856 Pregnancy Related Skin Change Skin Changes Alterations in the skin's appearance during pregnancy due to hormonal level changes. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C92883 Spermicidal Cream Spermicidal Cream A vaginal cream that is deleterious to sperm. C92886 Spermicide C92712 NICHD Pregnancy & Childbirth Terminology C92884 Spermicidal Foam Spermicidal Foam A vaginal foam that is deleterious to sperm. C92886 Spermicide C92712 NICHD Pregnancy & Childbirth Terminology C92885 Spermicidal Jelly Spermicidal Jelly A vaginal jelly that is deleterious to sperm. C92886 Spermicide C92712 NICHD Pregnancy & Childbirth Terminology C92886 Spermicide Spermicide A chemical product that is deleterious to sperms and can be in the form of either a jelly, foam, or cream. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C92887 Spinal Block Spinal Block A procedure in which a pharmaceutical agent is administered into the subarachnoid space, producing a loss of sensation at and below the level of the block. C64381 Regional Anesthesia Procedure C92712 NICHD Pregnancy & Childbirth Terminology C92888 Spontaneous Rupture of Membrane Spontaneous Rupture of Membrane SROM The normal rupture of the amniotic sac in a full term pregnant mother at the onset of labor. C92874 Rupture of Membrane C92712 NICHD Pregnancy & Childbirth Terminology C92889 ST Waveform Analysis ST Waveform Analysis Technology STAN A method of fetal ECG surveillance during labor that monitors the ST segment, to indicate any fetal hypoxia. C92714 Fetal Examination C92712 NICHD Pregnancy & Childbirth Terminology C92723 Stage of Labor Stages of Labor The various distinct periods of the labor and childbirth process. It involves uterine contractions and cervical dilation to expel the fetus and for the baby to be born. C21514 Temporal Qualifier C92712 NICHD Pregnancy & Childbirth Terminology C92857 Pregnancy Stretch Mark Stretch Marks The visible, linear scarring in the dermis, predominantly of the abdomen due to the stretching of tissue and related hormonal changes during pregnancy. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C92890 Stripping of Membrane Stripping of Membrane An intervention during labor and delivery, of gently sweeping the amniotic membrane to separate it from the attachment to the lower uterine segment. C92814 Induction of Labor C92712 NICHD Pregnancy & Childbirth Terminology C92892 Surgical Contraception Surgical Contraception Method A method of achieving contraception with the aid of a surgical procedure that prevents fertilization of an egg by a sperm. C37932 Contraception C15332 Gynecologic Surgical Procedure C92712 NICHD Pregnancy & Childbirth Terminology C15384 Surgical Incision Surgical Incision An intentional cut made to an individual's body with the intent of performing a diagnostic or therapeutic intervention. C25218 Intervention or Procedure C92712 NICHD Pregnancy & Childbirth Terminology C92911 Uterine Tachysystole Tachysystole A frequency of uterine contraction that is higher than normal. C92904 Uterine Contraction C92712 NICHD Pregnancy & Childbirth Terminology C92939 Teenage Pregnancy Teenage Pregnancy A pregnancy in an adolescent between the ages of thirteen and nineteen. C92933 Normal Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C92894 Therapeutic Abortion Procedure Therapeutic Abortion Intentional end of pregnancy by the removal or expulsion of a fetus or embryo from the uterus to preserve the health of the gravida (pregnant female). C89340 Obstetric Procedure C92712 NICHD Pregnancy & Childbirth Terminology C49236 Therapeutic Procedure Therapeutic Procedure An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process. C25218 Intervention or Procedure C92712 NICHD Pregnancy & Childbirth Terminology C92895 Third Stage of Labor Third Stage of Labor Placental Stage A stage during labor and childbirth that starts with the birth of the baby and ends with the delivery of the placenta. C92723 Stages of Labor C92712 NICHD Pregnancy & Childbirth Terminology C92896 Third Trimester Third Trimester The period of gestation that ranges from the 28th week of pregnancy until delivery. C69121 Trimester C92712 NICHD Pregnancy & Childbirth Terminology C3408 Thrombocytopenia Thrombocytopenia A condition in which there is an abnormally small number of platelets in the circulating blood. C26323 Hematological Disorder C92712 NICHD Pregnancy & Childbirth Terminology C92897 Tocodynamometry Tocodynamometry The recording of uterine muscle contractions during pregnancy and labor. C16847 Technique C92712 NICHD Pregnancy & Childbirth Terminology C34943 Toxemia of Pregnancy Toxemia A pregnancy induced hypertensive state that occurs after 20 weeks of gestation characterized by an increase in blood pressure, along with body swelling and proteinuria. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C3418 Toxoplasmosis Toxoplasmosis A parasitic disease contracted by the ingestion or fetal transmission of toxoplasma gondii. C27864 Parasitic Disease C92712 NICHD Pregnancy & Childbirth Terminology C92942 Transition Phase of Labor Transitional Phase of Labor The period during the first stage of labor and childbirth that involves strong uterine contractions and maximal cervical dilatation. C92798 First Stage of Labor C92712 NICHD Pregnancy & Childbirth Terminology C92898 Transverse Fetal Presentation Transverse Fetal Presentation A fetal position during delivery in which the alignment of the spine of the fetus is not parallel to the mother's spine. C92724 Fetal Presentation C92712 NICHD Pregnancy & Childbirth Terminology C92899 Transverse Occiput Presentation Transverse Occiput A fetal position during delivery in which the face is towards one of the mother's thighs while descending into the birth canal. C92926 Fetal Position C92712 NICHD Pregnancy & Childbirth Terminology C69121 Trimester Trimester A period of three months; especially one of the three three-month periods into which human pregnancy is divided. C92858 Pregnancy Time Period C92712 NICHD Pregnancy & Childbirth Terminology C92900 Triple Screen Triple Screen A screening method in which maternal blood levels of alpha-fetoprotein, unconjugated estriol and human chorionic gonadotrophin are calculated. The results are subsequently evaluated in relation to the mother's age, weight and fetal gestational age. C92803 Screening for Genetic Defect C92712 NICHD Pregnancy & Childbirth Terminology C92901 Tubal Ligation Tubal Ligation A method of female sterilization where the fallopian tubes are surgically ligated to prevent conception. C92892 Surgical Contraception Method C92712 NICHD Pregnancy & Childbirth Terminology C92946 Tubal Pregnancy Tubal Pregnancy An ectopic pregnancy that occurs in the fallopian tube instead of the uterine corpus. Causes include pelvic inflammatory disease and prior pelvic surgery. It may result in severe abdominal pain, vaginal bleeding, and tubal rupture. C34945 Ectopic Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C17230 Ultrasonography Ultrasound Imaging Ultrasound A technique in which high-frequency sound waves are bounced off internal organs and the echo pattern is converted into a 2 dimensional picture of the structures beneath the transducer. C18020 Diagnostic Procedure C16847 Technique C92712 NICHD Pregnancy & Childbirth Terminology C92902 Umbilical Cord Compression Umbilical Cord Compression An abnormal situation in utero, when there is increased pressure on the umbilical cord, which constricts blood supply to the fetus. C81236 Birth Complication C92712 NICHD Pregnancy & Childbirth Terminology C87126 Umbilical Cord Prolapse Umbilical Cord Prolapse Prolapsed Cord An obstetric emergency when the umbilical cord is pushed into the vagina ahead of the baby and becomes compressed, cutting off the flow of blood to the baby. C81236 Birth Complication C92712 NICHD Pregnancy & Childbirth Terminology C92903 Urge to Push Urge to Push A characteristic sign of impending birth in the mother during the second stage of labor; she feels like bearing down due to the pressure of the baby in the birth canal. C92881 Signs of Impending Birth C92712 NICHD Pregnancy & Childbirth Terminology C3430 Urinary System Disorder Urinary System Disorder Disorders of any part of the urologic system. C2991 Disease or Disorder C92712 NICHD Pregnancy & Childbirth Terminology C50791 Urinary Tract Infection Urinary Tract Infection A bacterial infectious process affecting any part of the urinary tract, most commonly the bladder and the urethra. Symptoms include urinary urgency and frequency, burning sensation during urination, lower abdominal discomfort, and cloudy urine. C3430 Urinary System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C92904 Uterine Contraction Uterine Contraction A tightening of the involuntary smooth muscles of the uterus. C92819 Intrapartum Process C92712 NICHD Pregnancy & Childbirth Terminology C92909 Uterine Involution Uterine Involution Atrophy or reduction of the size of the uterine corpus. C92935 Postpartum Process C92712 NICHD Pregnancy & Childbirth Terminology C92910 Uterine Souffle Uterine Souffle A soft murmur heard in auscultating a pregnant uterus. It is caused by the increased vascularity of pregnancy. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C81300 Vacuum Assisted Vaginal Delivery Vacuum Assisted Vaginal Delivery The method referring to the delivery of a fetus through the vaginal canal with assistance of a vacuum extractor device. C81301 Vaginal Assisted Delivery C92712 NICHD Pregnancy & Childbirth Terminology C81301 Vaginal Assisted Delivery Vaginal Assisted Delivery The method referring to the use of medical devices such as vacuum extractor or forceps to assist with the delivery of a fetus. C81303 Vaginal Delivery C92712 NICHD Pregnancy & Childbirth Terminology C81302 Vaginal Birth after Cesarean Vaginal Birth after Cesarean The method referring to the delivery of a fetus through the vaginal canal after the mother has had a cesarean delivery with a previous pregnancy. C81303 Vaginal Delivery C92712 NICHD Pregnancy & Childbirth Terminology C92912 Vaginal Birth Mechanism Vaginal Birth Mechanism The natural processes involved in giving birth vaginally. C92934 Labor and Delivery Process C92712 NICHD Pregnancy & Childbirth Terminology C92913 Vaginal Bleeding during Pregnancy Vaginal Bleeding Hemorrhage from the vagina that may range from light spotting to heavy flow during pregnancy. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C81303 Vaginal Delivery Vaginal Delivery The method referring to the delivery of a fetus through the vaginal canal. C81179 Delivery Procedure C92712 NICHD Pregnancy & Childbirth Terminology C42767 Vaginal Diaphragm Vaginal Diaphragm A medical contraceptive device of soft flexible material, usually of thin rubber, that is designed to cover the cervix uteri prior to sexual intercourse to prevent the entry of spermatozoa. To enhance efficacy, a spermicidal agent is often placed within the device. Antimicrobial agent(s) can also be used to prevent sexually transmitted diseases. Efficacy of vaginal diaphragm against infections is very limited. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C91199 Vaginal Ring Dosage Form Vaginal Ring A ring composed of active and/or inert ingredient(s), intended for administration in or around the vagina. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C92914 Variable Fetal Heart Rate Deceleration Variable Deceleration An irregular decrease in the fetal heart rate after the peak of an uterine contraction. C92789 Fetal Heart Rate Deceleration C92712 NICHD Pregnancy & Childbirth Terminology C87127 Vasa Previa Vasa Previa A serious condition in which blood vessels of the umbilical cord or the placenta cross the entrance to the birth canal, beneath the fetus; this can lead to rapid fetal blood loss during labor and delivery if the blood vessels tear as the cervix dilates and the membranes rupture. C81236 Birth Complication C92712 NICHD Pregnancy & Childbirth Terminology C15348 Vasectomy Vasectomy Surgical removal of part or all of the vas deferens. C92892 Surgical Contraception Method C92712 NICHD Pregnancy & Childbirth Terminology C34328 Vernix Caseosa Vernix Caseosa A white cheese-like protective material that covers the skin of a fetus. C13236 Biological Substance C92712 NICHD Pregnancy & Childbirth Terminology C92917 Vertex Presentation Vertex Presentation A fetal position during delivery in which the head of the fetus is flexed and it is first to descend into the birth canal. C92748 Cephalic Presentation C92712 NICHD Pregnancy & Childbirth Terminology C62754 Weight Gain Weight Gain An increase in overall body mass. C92720 Pregnancy Finding C92712 NICHD Pregnancy & Childbirth Terminology C92919 Withdrawal Contraception Withdrawal Contraception A birth control method adopted during sexual intercourse by withdrawing the penis from the vagina before ejaculation. C37932 Contraception C92712 NICHD Pregnancy & Childbirth Terminology