D C15222 Diet Diet The customary allowance of food and drink taken by a person or an animal from day to day, particularly one especially planned to meet specific requirements of the individual, including or excluding certain items of food; a prescribed course of eating and drinking in which the amount and kind of food, as well as the times at which it is to be taken, are regulated for therapeutic purposes or selected with reference to a particular state of health. C3367 Finding C89506 NICHD Newborn Screening Terminology D C3284 Obstruction Obstruction Blockage of the normal flow of the contents of an anatomical passageway. C3367 Finding C89506 NICHD Newborn Screening Terminology D C42614 Name Name The words or language units by which a thing is known. C20181 Conceptual Entity C89506 NICHD Newborn Screening Terminology D C63481 Physiologic Testing Physiologic Testing The examination of variables concerning organism or bodily functions. C20993 Clinical Assessment Tool C89506 NICHD Newborn Screening Terminology D C64546 Color Assessment Color Assessment A qualitative assessment of the color of a biological specimen. C20993 Clinical Assessment Tool C89506 NICHD Newborn Screening Terminology D C71460 Method Method A means, manner of procedure, or systematic course of actions that have to be performed in order to accomplish a particular goal. C16847 Technique C89506 NICHD Newborn Screening Terminology D C71898 Brand Name Brand Name The part of the name or logo associated with a specific product or service identifying and distinguishing it from varieties of the same product or service marketed by competing companies. C42614 Name C89506 NICHD Newborn Screening Terminology D C81250 Functional Assessment Functional Assessment An appraisal of the operation and performance of an object of interest. C20993 Clinical Assessment Tool C89506 NICHD Newborn Screening Terminology D C81265 Evaluation Method Evaluation Method A description of the technique for the appraisal of a subject or object. C71460 Method C89506 NICHD Newborn Screening Terminology D C81266 Examination Method Examination Method A description of the technique for the inspection of a subject or object. C71460 Method C89506 NICHD Newborn Screening Terminology D C81307 Estimation Method Estimation Method A description of the technique for the approximate calculation of a value. C71460 Method C89506 NICHD Newborn Screening Terminology D C15222 Diet Diet The customary allowance of food and drink taken by a person or an animal from day to day, particularly one especially planned to meet specific requirements of the individual, including or excluding certain items of food; a prescribed course of eating and drinking in which the amount and kind of food, as well as the times at which it is to be taken, are regulated for therapeutic purposes or selected with reference to a particular state of health. C3367 Finding C90259 NICHD Pediatric Terminology D C19337 Diagnostic Ultrasound Ultrasound Use of ultrasound for imaging or diagnostic purposes. Employs frequencies ranging from 1.6 to 10 megahertz. (DCTD-DIP) C92721 Screening and Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology D C20181 Conceptual Entity Conceptual Entity An organizational header for concepts representing mostly abstract entities. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology D C25499 Event Event Something that happens at a given place and time. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology D C3284 Obstruction Obstruction Blockage of the normal flow of the contents of an anatomical passageway. C3367 Finding C90259 NICHD Pediatric Terminology D C42614 Name Name The words or language units by which a thing is known. C20181 Conceptual Entity C90259 NICHD Pediatric Terminology D C62781 Doppler Ultrasound Ultrasonography Diagnostic imaging that uses sound waves (ultrasound) applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. C16847 Technique C90259 NICHD Pediatric Terminology D C63481 Physiologic Testing Physiologic Testing The examination of variables concerning organism or bodily functions. C20993 Clinical Assessment Tool C90259 NICHD Pediatric Terminology D C64546 Color Assessment Color Assessment A qualitative assessment of the color of a biological specimen. C20993 Clinical Assessment Tool C90259 NICHD Pediatric Terminology D C64851 Choriogonadotropin Beta Measurement Pregnancy Test A determination of the presence of Choriogonadotropin Beta protein. C92949 Pregnancy Test C90259 NICHD Pediatric Terminology D C71460 Method Method A means, manner of procedure, or systematic course of actions that have to be performed in order to accomplish a particular goal. C16847 Technique C90259 NICHD Pediatric Terminology D C71898 Brand Name Brand Name The part of the name or logo associated with a specific product or service identifying and distinguishing it from varieties of the same product or service marketed by competing companies. C42614 Name C90259 NICHD Pediatric Terminology D C81250 Functional Assessment Functional Assessment An appraisal of the operation and performance of an object of interest. C20993 Clinical Assessment Tool C90259 NICHD Pediatric Terminology D C81265 Evaluation Method Evaluation Method A description of the technique for the appraisal of a subject or object. C71460 Method C90259 NICHD Pediatric Terminology D C81266 Examination Method Examination Method A description of the technique for the inspection of a subject or object. C71460 Method C90259 NICHD Pediatric Terminology D C81307 Estimation Method Estimation Method A description of the technique for the approximate calculation of a value. C71460 Method C90259 NICHD Pediatric Terminology D C81317 Postnatal Postnatal The time period after birth. C92858 Pregnancy Time Period C90259 NICHD Pediatric Terminology D C92938 Release of Egg Release of Egg The process in which the mature ovarian Graffian follicle ruptures and discharges the ovum (egg) inside it. C16465 Conception C90259 NICHD Pediatric Terminology D C19337 Diagnostic Ultrasound Ultrasound Use of ultrasound for imaging or diagnostic purposes. Employs frequencies ranging from 1.6 to 10 megahertz. (DCTD-DIP) C92721 Screening and Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology D C25499 Event Event Something that happens at a given place and time. C90259 NICHD Pediatric Terminology C92712 NICHD Pregnancy & Childbirth Terminology D C62781 Doppler Ultrasound Ultrasonography Diagnostic imaging that uses sound waves (ultrasound) applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. C16847 Technique C92712 NICHD Pregnancy & Childbirth Terminology D C64851 Choriogonadotropin Beta Measurement Pregnancy Test A determination of the presence of Choriogonadotropin Beta protein. C92949 Pregnancy Test C92712 NICHD Pregnancy & Childbirth Terminology D C81317 Postnatal Postnatal The time period after birth. C92858 Pregnancy Time Period C92712 NICHD Pregnancy & Childbirth Terminology D C92938 Release of Egg Release of Egg The process in which the mature ovarian Graffian follicle ruptures and discharges the ovum (egg) inside it. C16465 Conception C92712 NICHD Pregnancy & Childbirth Terminology A C2890 Bacterial Infection Bacterial Disease An acute infectious disorder caused by gram positive or gram negative bacteria. Representative examples include pneumococcal , streptococcal, salmonella and meningeal infections. C26726 Infectious Disease C89506 NICHD Newborn Screening Terminology A C2931 Cardiovascular Disorder Cardiovascular Disorder A non-neoplastic or neoplastic disorder affecting the heart or the vessels (arteries, veins and lymph vessels). Representative examples of non-neoplastic cardiovascular disorders are endocarditis and hypertension. Representative examples of neoplastic cardiovascular disorders are endocardial myxoma and angiosarcoma. C2991 Disease or Disorder C89506 NICHD Newborn Screening Terminology A C1126 Haemophilus Influenzae B Vaccine Haemophilus Influenzae B Vaccine Hib Vaccine|PRP vaccine A vaccine against serotype b of the Gram-negative bacterium H. influenzae (Hib). Hib vaccines contain polysaccharide-protein conjugate antigens that produce greater host immune responses than first-generation purified polysaccharide vaccine. These vaccines may differ with regard to use of protein carriers, polysaccharides, diluents, and preservatives. C1455 Conjugate Vaccine C90259 NICHD Pediatric Terminology A C14187 Bacteria Bacteria Unicellular, prokaryotic organisms that reproduce by cell division and usually have cell walls; can be shaped like spheres, rods or spirals and can be found in virtually any environment. C14250 Organism C90259 NICHD Pediatric Terminology A C14226 Human Papillomavirus Human Papilloma Virus A strain of papillomavirus that can infect the skin and mucous membranes of humans. C14283 Virus C90259 NICHD Pediatric Terminology A C14250 Organism Organism A living entity. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology A C14259 Poliovirus Poliovirus An enterovirus comprised of an single-stranded positive sense RNA genome and a protein capsid. This virus is the human pathogen that causes poliomyelitis. C14283 Virus C90259 NICHD Pediatric Terminology A C14283 Virus Virus An infectious agent which consists of two parts, genetic material and a protein coat. These organisms lack independent metabolism, and they must infect the cells of other types of organisms to reproduce. Most viruses are capable of passing through fine filters that retain bacteria, and are not visible through a light microscope. C14250 Organism C90259 NICHD Pediatric Terminology A C14338 Human Papillomavirus-16 Human Papillomavirus-16 A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce skin and mucosal epithelial lesions. Human papillomavirus-16 (HPV16) has been directly linked to cervical cancer and is significantly associated with invasiveness. Progression from low- to high-grade neoplasia is often associated with the integration of the HPV16 genome into the host chromosome. C14226 Human Papilloma Virus C90259 NICHD Pediatric Terminology A C14377 Human Papillomavirus-18 Human Papillomavirus-18 A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce skin and mucosal epithelial lesions. Human papillomavirus-18 (HPV18) has been directly linked to cervical cancer and plays a role in the pathogenesis of the disease. The virus integrates its DNA at specific chromosomal locations, such as 8q24 and 12q15. The use of molecular markers for HPV18 infection may allow the identification of patients with early stage cervical cancer and those at high risk for disease recurrence. C14226 Human Papilloma Virus C90259 NICHD Pediatric Terminology A C1455 Conjugate Vaccine Conjugate Vaccine A category of vaccines created by covalently attaching an antigen from an organism to a carrier protein from the same organism to aid in the delivery of the immunogen. C97125 Polysaccharide Vaccine C90259 NICHD Pediatric Terminology A C15329 Surgical Procedure Surgical Procedure A diagnostic or treatment procedure performed by manual and/or instrumental means, often involving an incision and the removal or replacement of a diseased organ or tissue; of or relating to or involving or used in surgery or requiring or amenable to treatment by surgery. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology A C15332 Gynecological Surgical Procedure Gynecologic Surgical Procedure Surgery performed on the female reproductive system. C15329 Surgical Procedure C90259 NICHD Pediatric Terminology A C15429 Research Activity Research Activity Systematic investigation into a subject in order to discover facts, establish or revise a theory, or develop a plan of action based on the facts discovered. C16205 Healthcare Activity C90259 NICHD Pediatric Terminology A C1572 Recombinant Viral Vaccine Recombinant Viral Vaccine A vaccine produced from genetically engineered viral vector by introduction of foreign genetic materials to activate immune response in a host. C923 Vaccine C90259 NICHD Pediatric Terminology A C1643 Pneumococcal Polyvalent Vaccine Pneumococcal 23-valent Polysaccharide Vaccine An polyvalent vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. Pneumococcal polyvalent vaccine contains highly purified capsular antigens from the 23 most prevalent or invasive pneumococcal types of Streptococcus pneumoniae to ensure cross-protection. Following vaccination, protective capsular type-specific antibody levels typically develop by the third week; serotype-specific antibody levels generally decline after 5-10 years. C97125 Polysaccharide Vaccine C90259 NICHD Pediatric Terminology A C1909 Pharmacologic Substance Pharmacologic Substance An active natural, synthetic or semi-synthetic ingredient including endogenous body substance that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the human body, but does not include intermediates used in the synthesis of such ingredient (21 CFR 314.3(b)). C45306 Substance C90259 NICHD Pediatric Terminology A C1920 Attenuated Live Virus Vaccine Attenuated Live Virus Vaccine Live vaccines prepared from microorganisms which have undergone physical adaptation (e.g., by radiation or temperature conditioning) or serial passage in laboratory animal hosts or infected tissue/cell cultures, in order to produce avirulent mutant strains capable of inducing protective immunity. Live-attenuated vaccines are used when a CD8+ T Cell (cellular cytotoxicity) response is desired. C97116 Attenuated Live Vaccine C90259 NICHD Pediatric Terminology A C1951 Human Papilloma Virus Vaccine Recombinant Human Papilloma Virus Vaccine A recombinant vaccine of different types of HPV proteins which are well-conserved within types with a significant inter-type variation. C1572 Recombinant Viral Vaccine C90259 NICHD Pediatric Terminology A C26323 Hematologic and Lymphocytic Disorder Hematological Disorder A neoplastic or non-neoplastic disorder that affects the production and proliferation of the hematopoietic cells including lymphoid cells, the synthesis of hemoglobin, and/or the mechanisms of coagulation. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C2643 Trivalent Influenza Vaccine Trivalent Influenza Vaccine Flu prevention|Flu prophylaxis|Flu shot|Flu vaccination A synthetic vaccine consisting of three inactivated influenza viruses, two different influenza type A strains and one influenza type B strain. Trivalent influenza vaccine is formulated annually, based on influenza strains projected to be prevalent in the upcoming flu season. This agent may be formulated for injection or intranasal administration. C2848 Polyvalent Vaccine C90259 NICHD Pediatric Terminology A C2660 Tetanus Toxoid Vaccine Tetanus Toxoid Vaccine A preparation of formaldehyde-deactivated toxin isolated from the bacterium Clostridium tetani. Tetanus toxoid is used for booster injection and can stimulate the production of antitoxin antibodies. This agent may be used as an adjuvant in cancer vaccines. C96398 Toxoid Vaccine C90259 NICHD Pediatric Terminology A C26726 Infectious Disorder Infectious Disease A disorder resulting from the presence and activity of a microbial, viral, or parasitic agent. It can be transmitted by direct or indirect contact. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C26739 Sensorineural Deafness Sensorineural Hearing Loss Hearing loss caused by a problem in the inner ear or auditory nerve. A sensorineural loss often affects a person’s ability to hear some frequencies more than others. This means that sounds may be appear distorted, even with the use of a hearing aid. Sensorineural losses can range from mild to profound. C35731 Hearing Loss C90259 NICHD Pediatric Terminology A C26828 Meningitis Meningitis A disorder characterized by acute inflammation of the meninges of the brain and/or spinal cord. C26726 Infectious Disease C90259 NICHD Pediatric Terminology A C26835 Nervous System Disorder Neurologic Disorder A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C26871 Respiratory Disorder Respiratory System Disorder A non-neoplastic or neoplastic disorder that affects the tracheobronchial tree and/or the lung parenchyma. Representative examples include infections, carcinomas, and lymphomas. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C26920 Encephalopathy Encephalopathy A functional and/or structural disorder of the brain caused by diseases (e.g. liver disease, kidney disease), medications, chemicals, and injuries. C96413 Brain Disorder C90259 NICHD Pediatric Terminology A C27019 Male Reproductive System Disorder Male Reproductive System Disorder A non-neoplastic or neoplastic disorder that affects the male genital system. Representative examples of non-neoplastic disorders include infection, testicular torsion, and undescended testis. Representative examples of neoplastic disorders include germ cell tumors, carcinoma, lymphoma, and sarcoma. C4875 Reproductive System Disorder C90259 NICHD Pediatric Terminology A C27020 Female Reproductive System Disorder Female Reproductive System Disorder A non-neoplastic or neoplastic disorder that affects the female genital system. Representative examples of non-neoplastic disorders include infection, endometriosis, and adenomyosis. Representative examples of neoplastic disorders include germ cell tumors, carcinoma, lymphoma, and sarcoma. C4875 Reproductive System Disorder C90259 NICHD Pediatric Terminology A C27560 Neonatal Respiratory Distress Syndrome Neonatal Respiratory Distress Syndrome A condition of the newborn marked by dyspnea with cyanosis, most frequently occurring in premature infants, children of diabetic mothers and infants delivered by cesarean section, and sometimes with no predisposing cause. C97173 Congenital Abnormality of the Respiratory System C90259 NICHD Pediatric Terminology A C27561 Respiratory Distress Syndrome Respiratory Distress Syndrome A group of conditions characterized by failure of normal respiration caused by lack of lung surfactant. C26871 Respiratory System Disorder C90259 NICHD Pediatric Terminology A C27574 Connective and Soft Tissue Disorder Musculoskeletal System Disorder Any deviation from the normal structure or function of the musculoskeletal or connective tissue that is manifested by a characteristic set of symptoms and signs. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C27645 Conductive Hearing Loss Conductive Hearing Loss Hearing loss caused by a problem in the outer ear or middle ear. Conductive losses usually affect all frequencies to the same degree. These losses are not usually severe. C35731 Hearing Loss C90259 NICHD Pediatric Terminology A C27864 Parasitic Infection Parasitic Disease A successful invasion of a host by an organism that uses the host for food and shelter. C26726 Infectious Disease C90259 NICHD Pediatric Terminology A C28161 Intramuscular Route of Administration Intramuscular Route of Administration Intramuscular injection is a route of drug administration via injection into muscle tissue. Aqueous or oleaginous solutions and emulsions or suspensions may be administered. Absorption rates, delay in availability of the drug to the systemic circulation, and duration of effect are perfusion-limited, depend on molecular size of the agent, volume, and osmolarity of the drug solution, fat content of the injection site, and patient physical activity. C38291 Parenteral Route of Administration C90259 NICHD Pediatric Terminology A C2848 Polyvalent Vaccine Polyvalent Vaccine A vaccine designed to elicit an immune response either to more than one infectious agent or to several different antigenic determinants of a single agent. C923 Vaccine C90259 NICHD Pediatric Terminology A C2878 Anxiety Disorder Anxiety Disorder A category of psychiatric disorders which are characterized by anxious feelings or fear often accompanied by physical symptoms associated with anxiety. C2893 Psychiatric Disorder C90259 NICHD Pediatric Terminology A C2890 Bacterial Infection Bacterial Disease An acute infectious disorder caused by gram positive or gram negative bacteria. Representative examples include pneumococcal , streptococcal, salmonella and meningeal infections. C26726 Infectious Disease C90259 NICHD Pediatric Terminology A C29090 Hepatitis A Vaccine Hepatitis A Vaccine An inactivated virus vaccine that provides active immunization against hepatitis A virus (HAV). Immunization with hepatitis A vaccine induces the formation of anti-HAV antibodies which provide protection against hepatitis A infection. C29694 Inactivated Vaccine C90259 NICHD Pediatric Terminology A C29091 Hepatitis B Vaccine Recombinant Hepatitis B Vaccine A non-infectious mixture containing recombinant hepatitis B surface antigen (HBsAg) in a liquid vehicle. Immunization with the hepatitis B vaccine induces the formation of specific anti-hepatitis B antibodies and an active immunity against hepatitis B infection. C1572 Recombinant Viral Vaccine C90259 NICHD Pediatric Terminology A C2931 Cardiovascular Disorder Cardiovascular Disorder A non-neoplastic or neoplastic disorder affecting the heart or the vessels (arteries, veins and lymph vessels). Representative examples of non-neoplastic cardiovascular disorders are endocarditis and hypertension. Representative examples of neoplastic cardiovascular disorders are endocardial myxoma and angiosarcoma. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C2934 Central Nervous System Disorder Central Nervous System Disorder A non-neoplastic or neoplastic disorder which affects the brain and/or spinal cord. C26835 Neurologic Disorder C90259 NICHD Pediatric Terminology A C2960 Condyloma Acuminatum Genital Warts Condyloma Acuminatum A sexually transmitted papillary growth caused by the human papillomavirus. It usually arises in the skin and mucous membranes of the perianal region and external genitalia. C3439 Viral Disease C90259 NICHD Pediatric Terminology A C29694 Inactivated Vaccine Inactivated Vaccine A preparation of killed microorganisms that is intended to prevent or treat an infectious disease by inducing active immunity to the causative microorganism. C923 Vaccine C90259 NICHD Pediatric Terminology A C2978 Cyst Cyst A sac-like closed membranous structure that may be empty or contain fluid or amorphous material. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C2987 Diarrhea Diarrhea A condition of frequent and watery bowel movements. C4876 Symptom C90259 NICHD Pediatric Terminology A C29888 Mumps Mumps A contagious viral infection caused by the mumps virus. Symptoms include swollen and tender parotid glands, fever, muscle aches and fatigue. Due to vaccination programs, mumps has become a rare disease. C96411 Childhood Viral Disease C90259 NICHD Pediatric Terminology A C2990 Gastrointestinal Disorder Gastrointestinal Disorder A non-neoplastic or neoplastic disorder that affects the gastrointestinal tract, anus, liver, biliary system, and pancreas. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C2991 Disease or Disorder Disease or Disorder Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology A C3009 Endocrine Disorder Endocrine System Disorder Any deviation from the normal structure or function of the endocrine system that is manifested by a characteristic set of symptoms and signs. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C3020 Epilepsy Epilepsy A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions. C96413 Brain Disorder C90259 NICHD Pediatric Terminology A C3038 Fever Fever The elevation of the body's temperature above the upper limit of normal, usually taken as 37.7 degrees C. C4876 Symptom C90259 NICHD Pediatric Terminology A C307 Biological Agent Biologic Agent Biotechnology-derived pharmaceutical agents made from living organisms or their products. Includes recombinant proteins, monoclonal antibodies, and nucleic acids. C1909 Pharmacologic Substance C90259 NICHD Pediatric Terminology A C3096 Hepatitis A Infection Hepatitis A Acute inflammation of the liver caused by the hepatitis A virus. It is highly contagious and usually contracted through close contact with an infected individual or their feces, contaminated food or water. C3439 Viral Disease C90259 NICHD Pediatric Terminology A C3097 Hepatitis B Infection Hepatitis B A viral infection caused by the hepatitis B virus. C3439 Viral Disease C90259 NICHD Pediatric Terminology A C3114 Hypersensitivity Allergic Reaction A local or general reaction of an organism following contact with a specific allergen to which it has been previously exposed and to which it has become sensitized. C4876 Symptom C90259 NICHD Pediatric Terminology A C3262 Neoplasm Neoplasm A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C3303 Pain Pain The sensation of discomfort, distress, or agony, resulting from the stimulation of specialized nerve endings. C4876 Symptom C90259 NICHD Pediatric Terminology A C3333 Pneumonia Pneumonia An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, due to infections (viruses, fungi, mycoplasma, or bacteria), treatment (e.g. radiation), or exposure (inhalation) to chemicals. Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness. C26871 Respiratory System Disorder C90259 NICHD Pediatric Terminology A C3364 Septicemia Sepsis The presence of pathogenic microorganisms in the blood stream causing a rapidly progressing systemic reaction that may lead to shock. Symptoms include fever, chills, tachycardia, and increased respiratory rate. It is a medical emergency that requires urgent medical attention. C2890 Bacterial Disease C90259 NICHD Pediatric Terminology A C3371 Skin Disorder Integumentary System Disorder Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C3389 Post-Traumatic Stress Disorder Post-Traumatic Stress Disorder An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by intrusive recurring thoughts or images of the traumatic event; avoidance of anything associated with the event; a state of hyperarousal and diminished emotional responsiveness. These symptoms are present for at least one month and the disorder is usually long-term. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology A C3408 Thrombocytopenia Thrombocytopenia A condition in which there is an abnormally small number of platelets in the circulating blood. C26323 Hematological Disorder C90259 NICHD Pediatric Terminology A C3430 Urinary System Disorder Urinary System Disorder Disorders of any part of the urologic system. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C34362 Agoraphobia Agoraphobia An anxiety disorder characterized by an intense, irrational fear of venturing out into open places or situations in which help (or escape) might not be available should excessive anxiety or panic symptoms develop. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology A C34387 Anorexia Nervosa Anorexia Nervosa A disorder most often seen in adolescent females characterized by a refusal to maintain a minimally normal body weight, an intense fear of gaining weight, a disturbance in body image, and, in postmenarcheal females, the development of amenorrhea. C89332 Eating Disorder C90259 NICHD Pediatric Terminology A C3439 Viral Infection Viral Disease Viral Infection Any disease caused by a virus. C26726 Infectious Disease C90259 NICHD Pediatric Terminology A C3442 Vomiting Vomiting The reflex act of ejecting the contents of the stomach through the mouth. C4876 Symptom C90259 NICHD Pediatric Terminology A C34423 Bipolar Disorder Bipolar Disorder A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence. C2893 Psychiatric Disorder C90259 NICHD Pediatric Terminology A C34440 Bulimia Bulimia Nervosa A disorder characterized by recurrent episodes of binge-eating over which the individual feels a lack of control; these episodes of binge-eating are followed by recurrent compensatory behavior to prevent weight gain, usually self-induced vomiting. In addition, self-evaluation is unduly influenced by body image. C89332 Eating Disorder C90259 NICHD Pediatric Terminology A C34460 Cerebral Palsy Cerebral Palsy A group of disorders affecting the development of movement and posture, often accompanied by disturbances of sensation, perception, cognition, and behavior. It results from damage to the fetal or infant brain. C26835 Neurologic Disorder C89328 Pediatric Disease or Disorder C90259 NICHD Pediatric Terminology A C34527 Demyelinating Disorder Demyelinating Disorder A broad group of disorders that affect the myelin sheaths that cover the neurons. Myelin sheathes cover neuronal axons in the central and peripheral nervous system and function to increase travelling impulse speeds. Disruption of this sheath impairs neuronal transmission and can result in disorders such as multiple sclerosis and Guillain-Barre syndrome, among others. C26835 Neurologic Disorder C90259 NICHD Pediatric Terminology A C34541 Diphtheria Diphtheria A Gram-positive bacterial infection caused by Corynebacterium diphtheria. It usually involves the oral cavity, pharynx, and nasal cavity. Patients develop pseudomembranes in the affected areas and manifest signs and symptoms of an upper respiratory infection. The diphtheria toxin may cause myocarditis, polyneuritis, and other systemic effects. C2890 Bacterial Disease C90259 NICHD Pediatric Terminology A C34632 Gastroenteritis Gastroenteritis An inflammatory disorder that affects the upper and lower gastrointestinal tract. Most commonly, this is attributed to viruses; however bacteria, parasites or adverse reactions can also be the culprit. Symptoms include acute diarrhea and vomiting. C2990 Gastrointestinal Disorder C90259 NICHD Pediatric Terminology A C34662 Central Hearing Loss Central Hearing Loss Hearing loss caused by a problem along the pathway from the inner ear to the auditory region of the brain or in the brain itself. C35731 Hearing Loss C90259 NICHD Pediatric Terminology A C34797 Malaria Malaria A protozoan infection caused by the genus Plasmodium. There are four species of Plasmodium that can infect humans: Plasmodium falciparum, vivax, ovale, and malariae. It is transmitted to humans by infected mosquitoes. Signs and symptoms include paroxysmal high fever, sweating, chills, and anemia. C27864 Parasitic Disease C90259 NICHD Pediatric Terminology A C34927 Social Phobia Social Anxiety Disorder An anxiety disorder characterized by an intense, irrational fear of one or more social or performance situations in which the individual believes that he or she will be scrutinized by others. Exposure to social situations immediately provokes an anxiety response. In adults, the social phobia is recognized as excessive or unreasonable. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology A C34982 Retrolental Fibroplasia Retinopathy of Prematurity A bilateral retinopathy characterized by neovascularization, scarring, retinal detachment, and eventually blindness. It may be mild or severe. It occurs in babies born prematurely. Causes include oxygen toxicity and hypoxia. C97172 Congenital Abnormality of the Nervous System C90259 NICHD Pediatric Terminology A C35004 Childhood Schizophrenia Childhood Schizophrenia Schizophrenia occurring in childhood. C92190 Childhood Mental Disorder C90259 NICHD Pediatric Terminology A C35014 Separation Anxiety Disorder Separation Anxiety Disorder An anxiety disorder characterized by recurrent excessive distress due to fear of separation from the home or from major attachment figures; the distress is developmentally inappropriate and causes impairment in social, academic, or other areas of functioning. C92190 Childhood Mental Disorder C90259 NICHD Pediatric Terminology A C3507 Immune System Disorder Immunolymphatic System Disorder A disorder resulting from an abnormality in the immune system. -- 2003 C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C35078 Tourette Syndrome Tourette's Syndrome A neurologic disorder caused by defective metabolism of the neurotransmitters in the brain. It is characterized by repeated involuntary movements (motor tics) and uncontrollable vocal sounds (vocal tics). The symptoms are usually manifested before the age of eighteen. C96412 Brain Development Abnormality C90259 NICHD Pediatric Terminology A C35089 Typhoid Fever Typhoid Fever A bacterial infectious disorder contracted by consumption of food or drink contaminated with Salmonella typhi. This disorder is common in developing countries and can be treated with antibiotics. C2890 Bacterial Disease C90259 NICHD Pediatric Terminology A C35107 Congenital Genitourinary Abnormality Congenital Abnormality of the Genitourinary System An abnormality of the genitourinary system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology A C35126 Vision Disorder Vision Disorder Visual impairments limiting one or more of the basic functions of the eye: visual acuity, dark adaptation, color vision, or peripheral vision. These may result from eye diseases, optic nerve diseases, visual pathway diseases, occipital lobe diseases, ocular motility disorders' and other conditions. C63711 Sensory Disorder C90259 NICHD Pediatric Terminology A C35275 Visual Cortex Disorder Visual Cortex Disorder Cortical Visual Impairment A vision disorder that results from damage of the part of the cerebral cortex that is involved in the processing of visual information. C35126 Vision Disorder C90259 NICHD Pediatric Terminology A C35284 Specific Phobia Specific Phobia An anxiety disorder characterized by an intense, irrational fear cued by the presence or anticipation of a specific object or situation. Exposure to the phobic stimulus immediately provokes an anxiety response. In adults, the specific phobia is recognized as excessive or unreasonable. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology A C35470 Behavior-Related Disorder Behavioral Disorder A specific behavioral problem that occurs in persistent patterns and characteristic clusters and that causes clinically significant impairment. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C35547 Yellow Fever Virus Infection Yellow Fever Virus Infection A viral infection caused by a flavivirus called yellow fever virus. It is transmitted to humans from infected mosquitoes. The signs and symptoms range from a mild febrile illness to liver damage with jaundice and hemorrhages. C3439 Viral Disease C90259 NICHD Pediatric Terminology A C35550 Acute Poliomyelitis Poliomyelitis Polio An acute infectious disorder that affects the nervous system. It is caused by the poliovirus. The virus spreads by direct contact, and can be prevented by prophylaxis with the polio vaccine. C96411 Childhood Viral Disease C90259 NICHD Pediatric Terminology A C35729 Congenital Cardiovascular Abnormality Congenital Abnormality of the Circulatory System A heart or vascular abnormality which is inborn or present at birth. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology A C35731 Hearing Loss Hearing Loss A partial or complete loss of hearing in one or both ears. It is classified as conductive, sensory, or central. C63711 Sensory Disorder C90259 NICHD Pediatric Terminology A C3782 Cervical Intraepithelial Neoplasia Cervical Intraepithelial Neoplasia Squamous or glandular intraepithelial neoplasia that affects the cervical mucosal epithelium. There is no evidence of stromal invasion. According to the degree of cellular atypia and the associated architectural changes, it is classified as low or high grade. C3262 Neoplasm C90259 NICHD Pediatric Terminology A C37928 Confusion Confusion A mental state characterized by a lack of clear and orderly thought and behavior. C4876 Symptom C90259 NICHD Pediatric Terminology A C38114 Route of Administration Route of Administration Designation of the part of the body through which or into which, or the way in which, the medicinal product is intended to be introduced. In some cases a medicinal product can be intended for more than one route and/or method of administration. C16847 Technique C90259 NICHD Pediatric Terminology A C38141 Pneumococcal 7-Valent Conjugate Vaccine Pneumococcal 7-Valent Conjugate Vaccine An active immunizing agent used to prevent infection by the bacterium Streptococcus pneumoniae. Pneumococcal 7-valent conjugate vaccine consists of a solution of saccharides of the capsular antigens of Streptococcus serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F individually conjugated to diphtheria CRM 197 protein. C97123 Pneumococcal Conjugate Vaccine C90259 NICHD Pediatric Terminology A C38276 Intravenous Route of Administration Intravenous Route of Administration Administration of a drug within or into a vein or veins. Introduction of the drug directly into venous circulation results in 100% bioavailability due to an absence of the absorption phase, provides a precise and continuous mode of drug therapy, especially for drugs with a narrow therapeutic index. C38291 Parenteral Route of Administration C90259 NICHD Pediatric Terminology A C38284 Nasal Route of Administration Nasal Route of Administration Administration of a drug by the way of the nose. This often results in systemic action of the agent due to absorption through the nasal mucosa. The richly supplied vascular nature of the nasal mucosa coupled with its high drug permeation makes the nasal route of administration attractive for many drugs, including proteins and peptides. C38114 Route of Administration C90259 NICHD Pediatric Terminology A C38288 Oral Route of Administration Oral Route of Administration The introduction of a substance to the mouth or into the gastrointestinal tract by the way of the mouth, usually for systemic action. It is the most common, convenient, and usually the safest and least expensive route of drug administration, but it uses the most complicated pathway to the tissues and bioavailability varies. The disadvantages of method are hepatic first pass metabolism and enzymatic degradation of the drug within the gastrointestinal tract. This prohibits oral administration of certain classes of drugs especially peptides and proteins. C38114 Route of Administration C90259 NICHD Pediatric Terminology A C38291 Parenteral Route of Administration Parenteral Route of Administration Administration of a substance by some means other than through the gastrointestinal tract: usually through injection, infusion, or implantation. Predominantly, the drug action is systemic, but in some cases, it is confined to local area. C38114 Route of Administration C90259 NICHD Pediatric Terminology A C38299 Subcutaneous Route of Administration Subcutaneous Route of Administration Drug administration beneath the skin. It provides for relatively slow, sustained release of the drug. The rate of absorption into the blood is perfusion-limited, proportional to the amount of drug at the site and can be enhanced by chemical or physical stimulation of blood flow. Subcutaneous administration minimizes the risks associated with intravascular injection: for subcutaneous infusions, external and implantable pumps are used. C38291 Parenteral Route of Administration C90259 NICHD Pediatric Terminology A C39594 Skin Rash Skin Rash Any change in the skin which affects its appearance or texture. A rash may be localized to one part of the body, or affect all the skin. Rashes may cause the skin to change color, itch, become warm, bumpy, dry, cracked or blistered, swell and may be painful. C4876 Symptom C90259 NICHD Pediatric Terminology A C4077 Redness Redness Coloration of the skin; sign of inflammation C4876 Symptom C90259 NICHD Pediatric Terminology A C42734 Contraceptive Device Contraceptive Device A device designed to prevent conception through local or systemic effect, such as a barrier contraceptive, an intrauterine device, or a means of preventing ovulation (e.g., birth control pill). C62103 Device C90259 NICHD Pediatric Terminology A C4875 Reproductive System Disorder Reproductive System Disorder A non-neoplastic or neoplastic disorder that affects the male or female genital system. Representative examples of non-neoplastic disorders include infection, testicular torsion, endometriosis, and adenomyosis. Representative examples of neoplastic disorders include germ cell tumors, carcinoma, lymphoma, and sarcoma. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C5041 Speech Manifestations Speech Disorder A term referring to disorders characterized by the disruption of normal speech. It includes stuttering, lisps, dysarthria and voice disorders. C9229 Systemic Disorder C90259 NICHD Pediatric Terminology A C50896 Intraventricular Brain Hemorrhage Intraventricular Hemorrhage Bleeding into the brain's ventricles. C2931 Cardiovascular Disorder C90259 NICHD Pediatric Terminology A C53482 Influenza Influenza Flu An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system. C3439 Viral Disease C90259 NICHD Pediatric Terminology A C62651 Allergen Allergen A substance that elicits an allergic reaction. C45306 Substance C90259 NICHD Pediatric Terminology A C62761 Attenuated Bacteria Vaccine Attenuated Live Bacterial Vaccine Any vaccine created by reducing the virulence of bacteria but still keeping the bacteria viable (live). In the production of an attenuated vaccine, the infectious agent is altered so that it becomes harmless or less virulent. This is in contrast to those vaccines produced by "killing" the pathogen (inactivated vaccine). C97116 Attenuated Live Vaccine C90259 NICHD Pediatric Terminology A C63711 Neurosensory Disorder Sensory Disorder An interruption or alteration in the sensory activity or functions of the nervous system. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C70856 Observation Result Observational Result An outcome of observation represented as a text, qualitative, or quantitative parameter, code, image, graph, etc. C3367 Finding C90259 NICHD Pediatric Terminology A C71091 Human Herpesvirus 3 Varicella-Zoster Virus An icosahedral, enveloped virus containing a single molecule of linear double-stranded DNA of 125000 nucleotides that infects only humans. It is the causative agent of chickenpox and shingles. C14283 Virus C90259 NICHD Pediatric Terminology A C75488 Rett Syndrome Rett Syndrome A progressive neurologic disorder caused by mutations in the MECP2 gene on chromosome X. It almost exclusively affects girls. It is characterized by language and learning difficulties, poor communication skills, and repetitive hand motions. Other signs and symptoms include microcephaly, scoliosis, breathing abnormalities, and sleep disturbances. C97179 Pervasive Developmental Disorder C90259 NICHD Pediatric Terminology A C76205 Bordetella pertussis Bordetella pertussis A species of bacteria within the phylum Proteobacteria consisting of gram-negative aerobic coccobacillus that are the causative agent of pertussis. C14187 Bacteria C90259 NICHD Pediatric Terminology A C77199 Rotavirus Rotavirus A genus of double stranded RNA viruses that carry 11 unique double helix molecules of RNA that encode one or two proteins each. The RNA is surrounded by a three-layered icosahedral protein capsid. Viral particles are up to 76.5 nm in diameter and are not enveloped. C14283 Virus C90259 NICHD Pediatric Terminology A C80444 H1N1 Influenza H1N1 Influenza Swine flu An acute viral respiratory infection caused by a strain of influenza virus which is endemic in swine (pigs). Rarely reported in humans prior to 2009, the disease is caused by a mutated strain of swine influenza A (H1N1) virus. It is highly contagious and spreads mainly through coughing and sneezing. Signs and symptoms include fever, chills, coughing, sore throat headache, muscle ache, and generalized weakness. Antiviral medications are most effective in the first two days of the illness. C53482 Influenza C90259 NICHD Pediatric Terminology A C81182 Measurement Device Measurement Device Any device used to determine the dimension of an object. C62103 Device C90259 NICHD Pediatric Terminology A C84392 Mental Retardation Mental Retardation A developmental disorder characterized by less than average intelligence and significant limitations in adaptive behavior with onset before the age of 18. C92190 Childhood Mental Disorder C90259 NICHD Pediatric Terminology A C84479 Excessive Blood Clotting Thrombophilia A condition characterized by an abnormally high level of thrombi. Causes include thrombotic thrombocytopenic purpura, disseminated intravascular coagulation, bone marrow disorders, and antiphospholipid antibody syndrome. C26323 Hematological Disorder C90259 NICHD Pediatric Terminology A C84915 Necrotizing Enterocolitis Necrotizing Enterocolitis A serious, life-threatening disorder characterized by necrotic changes affecting portions of the small and large intestine. It is usually seen in neonates, particularly premature infants. Signs and symptoms include abdominal distention and tenderness, intestinal bleeding and ileus. It may lead to cardiovascular collapse and shock. C97171 Congenital Abnormality of the Digestive System C90259 NICHD Pediatric Terminology A C85185 Tetanus Tetanus A serious infectious disorder that follows wound contamination by the Gram-positive bacterium Clostridium tetani. The bacteria produce a neurotoxin called tetanospasmin, which causes muscle spasm in the jaw and other anatomic sites. C2890 Bacterial Disease C90259 NICHD Pediatric Terminology A C86605 Neisseria meningitidis Neisseria meningitidis A gram negative diplococcal bacterium that is a causative agent for meningitis and other meningococcal diseases. C14187 Bacteria C90259 NICHD Pediatric Terminology A C88411 Obsessive Compulsive Disorder Obsessive-Compulsive Disorder A disorder characterized by the presence of persistent and recurrent irrational thoughts (obsessions), resulting in marked anxiety and repetitive excessive behaviors (compulsions) as a way to try to decrease that anxiety. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology A C88412 Autism Spectrum Disorder Autism Spectrum Disorder A spectrum of developmental disorders that includes autism, Asperger syndrome, and Rett syndrome. Signs and symptoms include poor communication skills, defective social interactions, and repetitive behaviors. C97179 Pervasive Developmental Disorder C90259 NICHD Pediatric Terminology A C9039 Cervical Carcinoma Cervical Carcinoma A carcinoma arising from either the exocervical squamous epithelium or the endocervical glandular epithelium. The major histologic types of cervical carcinoma are: squamous carcinoma, adenocarcinoma, adenosquamous carcinoma, adenoid cystic carcinoma and undifferentiated carcinoma. C3262 Neoplasm C90259 NICHD Pediatric Terminology A C90599 Bronchopulmonary Dysplasia Bronchopulmonary Dysplasia A non-neoplastic lung disorder which develops in premature neonates who have been treated with oxygen and mechanical ventilation. C97173 Congenital Abnormality of the Respiratory System C90259 NICHD Pediatric Terminology A C91715 Inactivated Poliovirus Vaccine Inactivated Poliovirus Vaccine A vaccine consisting of inactivated poliovirus (IPV) types 1,2 and 3, with active immunizing activity against poliomyelitis. Upon intramuscular vaccination, inactivated poliovirus vaccine (IPV) activates the immune system to develop antibodies against polioviruses. C29694 Inactivated Vaccine C90259 NICHD Pediatric Terminology A C91717 Diphtheria Toxoid/Tetanus Toxoid/Acellular Pertussis Vaccine Adsorbed Diphtheria Toxoid/Tetanus Toxoid/Acellular Pertussis Vaccine DTP vaccine A vaccine containing detoxified tetanus toxoid, detoxified diphtheria toxoid and acellular pertussis antigens, adsorbed on aluminum phosphate, with active immunizing activity against diphtheria, tetanus and pertussis. The acellular pertussis vaccine components, produced by Bordetella pertussis, are detoxified pertussis toxin (PT), filamentous hemagglutinin (FHA), pertactin (PRN) and fimbriae types 2 and 3 (FIM). Intramuscular injection with this vaccine activates the immune system to develop antibodies against tetanus toxin, diphtheria toxin and B. pertussis antigens. C2848 Polyvalent Vaccine C90259 NICHD Pediatric Terminology A C91718 Diphtheria Toxoid/Tetanus Toxoid Vaccine Adsorbed Diphtheria Toxoid/Tetanus Toxoid Vaccine Adsorbed A vaccine containing detoxified tetanus toxoid and detoxified diphtheria toxoid adsorbed on aluminum phosphate with active immunizing activity against diphtheria and tetanus. Intramuscular injection with this vaccine activates the immune system to develop antibodies against tetanus toxin and diphtheria toxin. C96398 Toxoid Vaccine C90259 NICHD Pediatric Terminology A C92190 Pediatric Psychiatric Disorder Childhood Mental Disorder A category of psychiatric disorders which includes disorders most commonly identified in infancy, childhood, or adolescence. C89328 Pediatric Disease or Disorder C90259 NICHD Pediatric Terminology A C9229 Systemic Disease Systemic Disorder A clinical course finding indicating that a disease presents with systemic manifestations. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology A C923 Vaccine Vaccine Preparations containing substances with antigenic properties administered to activate the immune system, thereby inducing an immune response. Vaccines range from inactivated or attenuated microorganisms (bacteria and viruses), enhanced autologous tumor cells, tumor antigens or epitopes that are used to elicit host immune responses. Vaccines are used for the prevention, amelioration, or treatment of infectious diseases and cancer. C307 Biologic Agent C90259 NICHD Pediatric Terminology A C92561 Developmental Coordination Disorder Developmental coordination disorder Developmental Dyspraxia A disorder characterized by an impairment in the development of an individual's motor coordination skills; this impairment in motor development is not due to a medical condition. C89338 Neurodevelopmental Disorder C92190 Childhood Mental Disorder C90259 NICHD Pediatric Terminology A C92569 Selective Mutism Selective Mutism A persistent failure to speak in certain social situations (i.e., school) where speaking is expected, despite speaking in other situations. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology A C92621 Acute Stress Disorder Acute Stress Disorder An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by dissociative symptoms; vivid recollections of the traumatic event; avoidance of stimuli associated with the traumatic event; and a constant state of hyperarousal for no more than one month. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology A C92622 Generalized Anxiety Disorder Generalized Anxiety Disorder An anxiety disorder characterized by excessive and difficult-to-control worry about a number of life situations. The worry is accompanied by restlessness, fatigue, inability to concentrate, irritability, muscle tension, and/or sleep disturbance and lasts for at least 6 months. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology A C96391 Meningococcal Conjugate Vaccine MCV4 Meningococcal Conjugate Vaccine MCV-4 A conjugate vaccine of meningococcal polysaccharide used for active immunization against invasive meningococcal disease caused by Neisseria meningiditis serogroups A, C, Y, and W-135. C1455 Conjugate Vaccine C90259 NICHD Pediatric Terminology A C96394 Rotavirus Vaccine Rotavirus Vaccine A viral vaccine that prevents against rotavirus infection, the leading cause of severe acute gastroenteritis. C1920 Attenuated Live Virus Vaccine C90259 NICHD Pediatric Terminology A C96395 Varicella Vaccine Varicella Vaccine Chickenpox Vaccine|Shingles Vaccine A live attenuated virus vaccine used to prevent chickenpox and shingles, which is caused by varicella-zoster virus (VZV). C1920 Attenuated Live Virus Vaccine C90259 NICHD Pediatric Terminology A C96396 Yellow Fever Vaccine Yellow Fever Vaccine A live, attenuated viral vaccine to prevent yellow fever, endemic to parts of Africa and South America. C1920 Attenuated Live Virus Vaccine C90259 NICHD Pediatric Terminology A C96398 Toxoid Vaccine Toxoid Vaccine Any vaccine that contains an inactivated toxic substance used for disease prophylaxis or to vaccinate against snake bites. C923 Vaccine C90259 NICHD Pediatric Terminology A C96401 Oral Polio Vaccine Oral Polio Vaccine A vaccine that contains live attenuated polio virus. It is administered orally as polio prophylaxis in many areas of the world, but not in the U.S. since 2000. C1920 Attenuated Live Virus Vaccine C90259 NICHD Pediatric Terminology A C96402 Live Attenuated Influenza Vaccine Live Attenuated Influenza Vaccine Nasal Spray Flu Vaccine A vaccine that contains live attenuated influenza virus (LAIV) particles. This vaccine is administered intranasally for influenza prophylaxis. Not all populations are good candidates for LAIV; the very young, elderly, asthmatics and those with health impaired may be better treated with the trivalent inactivated vaccine that is administered intramuscularly. C1920 Attenuated Live Virus Vaccine C90259 NICHD Pediatric Terminology A C96403 Measles/Mumps/Rubella Vaccine Measles Mumps Rubella Vaccine A trivalent vaccine containing live attenuated viruses that can cause measles, mumps and rubella. It is an injection administered subcutaneously in two separate doses. C1920 Attenuated Live Virus Vaccine C90259 NICHD Pediatric Terminology A C96405 Tetanus and Diphtheria Toxoids Adsorbed Tetanus and Diphtheria Toxoids Adsorbed A sterile, intramuscular suspension of alum (aluminum potassium sulfate)-precipitated toxoids indicated for active immunization for the prevention of tetanus and diphtheria for use in persons 7 years of age or older. C96398 Toxoid Vaccine C90259 NICHD Pediatric Terminology A C96406 Rubeola Infection Measles Rubeola A highly contagious viral infection caused by the measles virus. Symptoms appear 8-12 days after exposure and include a rash, cough, fever and muscle pains that can last 4-7 days. Measles vaccines are available to provide prophylaxis, usually combined with mumps and rubella vaccines (MMR). C96411 Childhood Viral Disease C90259 NICHD Pediatric Terminology A C96408 Influenza Vaccination Influenza Vaccination The administration of live or attenuated influenza virus for the prophylaxis of influenza. C15258 Immunization C90259 NICHD Pediatric Terminology A C96409 Polio Vaccination Polio Vaccination The administration a series of either live or inactivated poliovirus for the prophylaxis of poliomyelitis. C15258 Immunization C90259 NICHD Pediatric Terminology A C96410 Dyslexia Dyslexia A learning disorder characterized by an impairment in processing written words. Reading difficulties can include distortions, omissions or substitutions of characters. Oral and silent reading difficulties can include faulty and slow comprehension. C89334 Learning Disorder C90259 NICHD Pediatric Terminology A C96411 Pediatric Viral Infection Childhood Viral Disease A viral infection that occurs during childhood. C89328 Pediatric Disease or Disorder C3439 Viral Disease C90259 NICHD Pediatric Terminology A C96412 Brain Developmental Abnormality Brain Development Abnormality A group of congenital or acquired disorders that affect the normal development of the brain. C89338 Neurodevelopmental Disorder C90259 NICHD Pediatric Terminology A C96413 Brain Disorder Brain Disorder A non-neoplastic or neoplastic disorder that affects the brain. C2934 Central Nervous System Disorder C90259 NICHD Pediatric Terminology A C96519 Meningococcal Polysaccharide Vaccine MPSV4 Meningococcal Polysaccharide Vaccine MPSV-4 A polysaccharide vaccine used to prevent contraction of meningococcal meningitis. C97125 Polysaccharide Vaccine C90259 NICHD Pediatric Terminology A C97109 Blindness Blindness The lack of vision. It is caused by neurological or physiological factors. C35126 Vision Disorder C90259 NICHD Pediatric Terminology A C97116 Attenuated Live Vaccine Attenuated Live Vaccine Any vaccine created by reducing the virulence of the infectious agent but still keeping the agent viable (live). In the production of an attenuated vaccine, the infectious agent is altered so that it becomes harmless or less virulent. This is in contrast to those vaccines produced by killing the pathogen (inactivated vaccine). C923 Vaccine C90259 NICHD Pediatric Terminology A C97120 Pneumococcal 10-valent Conjugate Vaccine Pneumococcal 10-valent Conjugate Vaccine An active immunizing vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. It is indicated for disease caused by serotypes 1, 5, 4, 6B, 7, 9V, 14, 18C, 19F, and 23F. C97123 Pneumococcal Conjugate Vaccine C90259 NICHD Pediatric Terminology A C97121 Pneumococcal 13-valent Conjugate Vaccine Pneumococcal 13-valent Conjugate Vaccine An active immunizing vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. It is indicated for disease caused by serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F. It can also be used to prevent against otitis media by serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F. C97123 Pneumococcal Conjugate Vaccine C90259 NICHD Pediatric Terminology A C97122 Diphtheria Toxoid/Tetanus Toxoid/Inactivated Pertussis Vaccine Diphtheria Toxoid/Tetanus Toxoid/Inactivated Pertussis Vaccine DTP A vaccine containing detoxified tetanus toxoid, detoxified diphtheria toxoid and inactivated pertussis antigens. C2848 Polyvalent Vaccine C90259 NICHD Pediatric Terminology A C97123 Pneumococcal Conjugate Vaccine Pneumococcal Conjugate Vaccine An active immunizing vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. It consists of a solution of saccharides of the capsular antigens of Streptococcus serotypes individually conjugated to proteins. C1455 Conjugate Vaccine C90259 NICHD Pediatric Terminology A C97125 Polysaccharide Vaccine Polysaccharide Vaccine A category of vaccines that use the extracted and purified outer polysaccharide coat of the particular bacteria. C923 Vaccine C90259 NICHD Pediatric Terminology A C97126 Ty21a Typhoid Vaccine Ty21a Typhoid Vaccine A live attenuated oral virus vaccine used to prevent typhoid, which is caused by Salmonella typhi. C62761 Attenuated Live Bacterial Vaccine C90259 NICHD Pediatric Terminology A C97127 Vi Capsular Polysaccharide Typhoid Vaccine Vi Capsular Polysaccharide Typhoid Vaccine A live attenuated injectable virus vaccine used to prevent typhoid, which is caused by Salmonella typhi. C97125 Polysaccharide Vaccine C90259 NICHD Pediatric Terminology A C97132 Chicken Pox Infection Chicken Pox A contagious childhood disorder caused by the varicella zoster virus. It is transmitted via respiratory secretions and contact with chickenpox blister contents. It presents with a vesicular skin rush, usually associated with fever, headache, and myalgias. The pruritic fluid-filled vesicles occur 10-21 days after exposure and last for 3-4 days. An additional 3-4 days of malaise follows before the affected individual feels better. An individual is contagious 1-2 days prior to the appearance of the blisters until all blisters are crusted over. Generally, healthy individuals recover without complications. C96411 Childhood Viral Disease C90259 NICHD Pediatric Terminology A C97150 NICHD Neurological Development Terminology NICHD Neurological Development Terminology Terminology for concepts associated with disorders of neurological development in the pediatric population that has been contributed by the National Institute of Child Health and Human Development. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology A C97151 Systemic Congenital Disorder Systemic Congenital Disorder An inherited disorder that presents with systemic manifestations. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology A C97155 Language Disorder Language Disorder A category of disorders characterized by an impairment in the development of an individual's language capabilities, which is in contrast to his/her non-verbal intellect. C92190 Childhood Mental Disorder C90259 NICHD Pediatric Terminology A C97159 Asperger Syndrome Asperger Syndrome A disorder most often diagnosed in the pediatric years in which the individual displays marked impairment in social interaction and a repetitive, stereotyped pattern of behavior. The individual, however, displays no delay in language or cognitive development, which differentiates Asperger Syndrome from autism. C88412 Autism Spectrum Disorder C90259 NICHD Pediatric Terminology A C97160 Attention Deficit Hyperactivity Disorder Attention Deficit Hyperactivity Disorder A disorder characterized by a marked pattern of inattention and/or hyperactivity-impulsivity that is inconsistent with developmental level and clearly interferes with functioning in at least two settings (e.g. at home and at school). At least some of the symptoms must be present before the age of 7 years. C35470 Behavioral Disorder C90259 NICHD Pediatric Terminology A C97161 Autism Autism A disorder characterized by marked impairments in social interaction and communication accompanied by a pattern of repetitive, stereotyped behaviors and activities. Developmental delays in social interaction and language surface prior to age 3 years. C88412 Autism Spectrum Disorder C90259 NICHD Pediatric Terminology A C97162 Binge Eating Disorder Binge Eating Disorder A disorder characterized by recurrent episodes of binge-eating over which the individual feels a lack of control and a sense of disgust and shame; unlike bulimia, however, there is no attempt to compensate for the binge-eating through vomiting or fasting. C89332 Eating Disorder C90259 NICHD Pediatric Terminology A C97163 Childhood Depression Childhood Depression Similar to depression in adults, childhood depression is characterized by a prolonged depressed or irritable mood accompanied by a significant loss of interest in activities, changes in appetite or sleep, decreased energy, feelings of worthlessness, and/or recurrent thoughts of death or suicide. C92190 Childhood Mental Disorder C90259 NICHD Pediatric Terminology A C97164 Childhood Disintegrative Disorder Childhood Disintegrative Disorder A pediatric disorder characterized by normal development for at least the first two years of life followed by a severe regression in language, social interaction, bowel or bladder control, and/or motor skills. The affected individual may also exhibit repetitive and stereotyped patterns of behavior similar to autism. C97179 Pervasive Developmental Disorder C90259 NICHD Pediatric Terminology A C97165 Dyscalculia Dyscalculia A wide group of related learning disorders characterized by difficulties with mathematics and manipulating numbers; the difficulty with math may be caused or exacerbated by visuo-spatial or language processing difficulties. C89334 Learning Disorder C90259 NICHD Pediatric Terminology A C97166 Echolalia Echolalia A symptom of neurologic or psychiatric dysfunction in which the individual involuntarily and meaninglessly repeats a recently heard word, series of words, or a song. C97170 Central Auditory Processing Disorder C90259 NICHD Pediatric Terminology A C97167 Anemia of Prematurity Anemia of Prematurity A blood disorder characterized by low hemoglobin levels in premature neonates that usually spontaneously resolves within 3-6 months post birth. A combination of factors including the transition from the liver to the bone marrow for erythropoiesis in a neonate, blood loss experienced during delivery, the shortened life span of fetal blood cells, and an acclimation to a relatively hyperoxic environment outside the womb can predispose a neonate to this condition. C35729 Congenital Abnormality of the Circulatory System C90259 NICHD Pediatric Terminology A C97168 Ataxic Cerebral Palsy Ataxic Cerebral Palsy The least common subtype of cerebral palsy, in which the individual displays hypotonia, a loss of motor coordination, and an intention tremor. Individuals with ataxic cerebral palsy walk very unsteadily, with a wide-based gait. C34460 Cerebral Palsy C90259 NICHD Pediatric Terminology A C97169 Athetoid Cerebral Palsy Athetoid Cerebral Palsy A subtype of cerebral palsy characterized by involuntary, purposeless writhing movements which affect the hands, feet, arms, and legs; the face and tongue may be affected as well, leading to involuntary grimacing, drooling, dysarthria and difficulty eating. C34460 Cerebral Palsy C90259 NICHD Pediatric Terminology A C97170 Central Auditory Processing Disorder Central Auditory Processing Disorder A disorder characterized by impairment of the auditory processing, resulting in deficiencies in the recognition and interpretation of sounds by the brain. Causes include brain maturation delays and brain traumas or tumors. C97155 Language Disorder C90259 NICHD Pediatric Terminology A C97171 Congenital Gastrointestinal Disorder Congenital Abnormality of the Digestive System An abnormality of the digestive system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology A C97172 Congenital Nervous System Disorder Congenital Abnormality of the Nervous System An abnormality of the nervous system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology A C97173 Congenital Respiratory System Disorder Congenital Abnormality of the Respiratory System An abnormality of the respiratory system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology A C97174 Congenital Skin Disorder Congenital Abnormality of the Skin A skin abnormality that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology A C97175 Low Vision Low Vision Reduced ability to perceive visual stimuli. C35126 Vision Disorder C90259 NICHD Pediatric Terminology A C97176 Maternal Obesity Maternal Obesity Obesity in a female who has a child. C26836 Nutritional Disorder C90259 NICHD Pediatric Terminology A C97177 Mixed Cerebral Palsy Mixed Cerebral Palsy A subtype of cerebral palsy characterized by both the tight muscle tone of spastic cerebral palsy and the writhing, involuntary muscle movements of athetoid cerebral palsy. C34460 Cerebral Palsy C90259 NICHD Pediatric Terminology A C97178 Mixed Hearing Loss Mixed Hearing Loss A combination of conductive and sensorineural losses. C35731 Hearing Loss C90259 NICHD Pediatric Terminology A C97179 Pervasive Developmental Disorder Pervasive Developmental Disorder A category of developmental disorders characterized by impaired communication and socialization skills. The impairments are incongruent with the individual's developmental level or mental age. These disorders can be associated with general medical or genetic conditions. C96412 Brain Development Abnormality C89338 Neurodevelopmental Disorder C90259 NICHD Pediatric Terminology A C97193 Panic Disorder without Agoraphobia Panic Disorder without Agoraphobia A disorder in which an individual experiences recurrent, unexpected panic attacks and persistent concern about having additional panic attacks. Agoraphobia is not a component of this disorder. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology A C97194 Panic Disorder with Agoraphobia Panic Disorder with Agoraphobia A disorder in which an individual experiences recurrent, unexpected panic attacks and persistent concern about having additional panic attacks. Agoraphobia is a component of this disorder. C2878 Anxiety Disorder C90259 NICHD Pediatric Terminology A C97250 Intellectual Disability Intellectual Disabilities A broad category of disorders characterized by an impairment to the intelligence an individual possesses. These impairments can result from trauma, birth or disease and are not restricted to any particular age group. C96413 Brain Disorder C90259 NICHD Pediatric Terminology A C3408 Thrombocytopenia Thrombocytopenia A condition in which there is an abnormally small number of platelets in the circulating blood. C26323 Hematological Disorder C92712 NICHD Pregnancy & Childbirth Terminology A C3430 Urinary System Disorder Urinary System Disorder Disorders of any part of the urologic system. C2991 Disease or Disorder C92712 NICHD Pregnancy & Childbirth Terminology A C1126 Haemophilus Influenzae B Vaccine Haemophilus Influenzae B Vaccine Hib Vaccine|PRP vaccine A vaccine against serotype b of the Gram-negative bacterium H. influenzae (Hib). Hib vaccines contain polysaccharide-protein conjugate antigens that produce greater host immune responses than first-generation purified polysaccharide vaccine. These vaccines may differ with regard to use of protein carriers, polysaccharides, diluents, and preservatives. C1455 Conjugate Vaccine C96388 NICHD Childhood Immunization Terminology A C14187 Bacteria Bacteria Unicellular, prokaryotic organisms that reproduce by cell division and usually have cell walls; can be shaped like spheres, rods or spirals and can be found in virtually any environment. C14250 Organism C96388 NICHD Childhood Immunization Terminology A C14226 Human Papillomavirus Human Papilloma Virus A strain of papillomavirus that can infect the skin and mucous membranes of humans. C14283 Virus C96388 NICHD Childhood Immunization Terminology A C14250 Organism Organism A living entity. C90259 NICHD Pediatric Terminology C96388 NICHD Childhood Immunization Terminology A C14259 Poliovirus Poliovirus An enterovirus comprised of an single-stranded positive sense RNA genome and a protein capsid. This virus is the human pathogen that causes poliomyelitis. C14283 Virus C96388 NICHD Childhood Immunization Terminology A C14283 Virus Virus An infectious agent which consists of two parts, genetic material and a protein coat. These organisms lack independent metabolism, and they must infect the cells of other types of organisms to reproduce. Most viruses are capable of passing through fine filters that retain bacteria, and are not visible through a light microscope. C14250 Organism C96388 NICHD Childhood Immunization Terminology A C14338 Human Papillomavirus-16 Human Papillomavirus-16 A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce skin and mucosal epithelial lesions. Human papillomavirus-16 (HPV16) has been directly linked to cervical cancer and is significantly associated with invasiveness. Progression from low- to high-grade neoplasia is often associated with the integration of the HPV16 genome into the host chromosome. C14226 Human Papilloma Virus C96388 NICHD Childhood Immunization Terminology A C14377 Human Papillomavirus-18 Human Papillomavirus-18 A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce skin and mucosal epithelial lesions. Human papillomavirus-18 (HPV18) has been directly linked to cervical cancer and plays a role in the pathogenesis of the disease. The virus integrates its DNA at specific chromosomal locations, such as 8q24 and 12q15. The use of molecular markers for HPV18 infection may allow the identification of patients with early stage cervical cancer and those at high risk for disease recurrence. C14226 Human Papilloma Virus C96388 NICHD Childhood Immunization Terminology A C1455 Conjugate Vaccine Conjugate Vaccine A category of vaccines created by covalently attaching an antigen from an organism to a carrier protein from the same organism to aid in the delivery of the immunogen. C97125 Polysaccharide Vaccine C96388 NICHD Childhood Immunization Terminology A C15258 Immunization Immunization Inoculating an individual with either killed or live agents to prevent contraction of a disease. C15843 Preventive Intervention C96388 NICHD Childhood Immunization Terminology A C1572 Recombinant Viral Vaccine Recombinant Viral Vaccine A vaccine produced from genetically engineered viral vector by introduction of foreign genetic materials to activate immune response in a host. C923 Vaccine C96388 NICHD Childhood Immunization Terminology A C1643 Pneumococcal Polyvalent Vaccine Pneumococcal 23-valent Polysaccharide Vaccine An polyvalent vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. Pneumococcal polyvalent vaccine contains highly purified capsular antigens from the 23 most prevalent or invasive pneumococcal types of Streptococcus pneumoniae to ensure cross-protection. Following vaccination, protective capsular type-specific antibody levels typically develop by the third week; serotype-specific antibody levels generally decline after 5-10 years. C97125 Polysaccharide Vaccine C96388 NICHD Childhood Immunization Terminology A C1909 Pharmacologic Substance Pharmacologic Substance An active natural, synthetic or semi-synthetic ingredient including endogenous body substance that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the human body, but does not include intermediates used in the synthesis of such ingredient (21 CFR 314.3(b)). C45306 Substance C96388 NICHD Childhood Immunization Terminology A C1920 Attenuated Live Virus Vaccine Attenuated Live Virus Vaccine Live vaccines prepared from microorganisms which have undergone physical adaptation (e.g., by radiation or temperature conditioning) or serial passage in laboratory animal hosts or infected tissue/cell cultures, in order to produce avirulent mutant strains capable of inducing protective immunity. Live-attenuated vaccines are used when a CD8+ T Cell (cellular cytotoxicity) response is desired. C97116 Attenuated Live Vaccine C96388 NICHD Childhood Immunization Terminology A C1951 Human Papilloma Virus Vaccine Recombinant Human Papilloma Virus Vaccine A recombinant vaccine of different types of HPV proteins which are well-conserved within types with a significant inter-type variation. C1572 Recombinant Viral Vaccine C96388 NICHD Childhood Immunization Terminology A C26323 Hematologic and Lymphocytic Disorder Hematological Disorder A neoplastic or non-neoplastic disorder that affects the production and proliferation of the hematopoietic cells including lymphoid cells, the synthesis of hemoglobin, and/or the mechanisms of coagulation. C2991 Disease or Disorder C96388 NICHD Childhood Immunization Terminology A C2643 Trivalent Influenza Vaccine Trivalent Influenza Vaccine Flu prevention|Flu prophylaxis|Flu shot|Flu vaccination A synthetic vaccine consisting of three inactivated influenza viruses, two different influenza type A strains and one influenza type B strain. Trivalent influenza vaccine is formulated annually, based on influenza strains projected to be prevalent in the upcoming flu season. This agent may be formulated for injection or intranasal administration. C2848 Polyvalent Vaccine C96388 NICHD Childhood Immunization Terminology A C2660 Tetanus Toxoid Vaccine Tetanus Toxoid Vaccine A preparation of formaldehyde-deactivated toxin isolated from the bacterium Clostridium tetani. Tetanus toxoid is used for booster injection and can stimulate the production of antitoxin antibodies. This agent may be used as an adjuvant in cancer vaccines. C96398 Toxoid Vaccine C96388 NICHD Childhood Immunization Terminology A C26726 Infectious Disorder Infectious Disease A disorder resulting from the presence and activity of a microbial, viral, or parasitic agent. It can be transmitted by direct or indirect contact. C2991 Disease or Disorder C96388 NICHD Childhood Immunization Terminology A C26828 Meningitis Meningitis A disorder characterized by acute inflammation of the meninges of the brain and/or spinal cord. C26726 Infectious Disease C96388 NICHD Childhood Immunization Terminology A C26835 Nervous System Disorder Neurologic Disorder A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves. C2991 Disease or Disorder C96388 NICHD Childhood Immunization Terminology A C27644 Deafness Deafness An inherited or acquired condition characterized by a partial or complete loss of hearing in one or both ears. The level of impairment varies from a mild but important loss of sensitivity to a total loss of hearing. C35731 Hearing Loss C96388 NICHD Childhood Immunization Terminology A C27864 Parasitic Infection Parasitic Disease A successful invasion of a host by an organism that uses the host for food and shelter. C26726 Infectious Disease C96388 NICHD Childhood Immunization Terminology A C28161 Intramuscular Route of Administration Intramuscular Route of Administration Intramuscular injection is a route of drug administration via injection into muscle tissue. Aqueous or oleaginous solutions and emulsions or suspensions may be administered. Absorption rates, delay in availability of the drug to the systemic circulation, and duration of effect are perfusion-limited, depend on molecular size of the agent, volume, and osmolarity of the drug solution, fat content of the injection site, and patient physical activity. C38291 Parenteral Route of Administration C96388 NICHD Childhood Immunization Terminology A C2848 Polyvalent Vaccine Polyvalent Vaccine A vaccine designed to elicit an immune response either to more than one infectious agent or to several different antigenic determinants of a single agent. C923 Vaccine C96388 NICHD Childhood Immunization Terminology A C2890 Bacterial Infection Bacterial Disease An acute infectious disorder caused by gram positive or gram negative bacteria. Representative examples include pneumococcal , streptococcal, salmonella and meningeal infections. C26726 Infectious Disease C96388 NICHD Childhood Immunization Terminology A C29090 Hepatitis A Vaccine Hepatitis A Vaccine An inactivated virus vaccine that provides active immunization against hepatitis A virus (HAV). Immunization with hepatitis A vaccine induces the formation of anti-HAV antibodies which provide protection against hepatitis A infection. C29694 Inactivated Vaccine C96388 NICHD Childhood Immunization Terminology A C29091 Hepatitis B Vaccine Recombinant Hepatitis B Vaccine A non-infectious mixture containing recombinant hepatitis B surface antigen (HBsAg) in a liquid vehicle. Immunization with the hepatitis B vaccine induces the formation of specific anti-hepatitis B antibodies and an active immunity against hepatitis B infection. C1572 Recombinant Viral Vaccine C96388 NICHD Childhood Immunization Terminology A C2960 Condyloma Acuminatum Genital Warts Condyloma Acuminatum A sexually transmitted papillary growth caused by the human papillomavirus. It usually arises in the skin and mucous membranes of the perianal region and external genitalia. C3439 Viral Disease C96388 NICHD Childhood Immunization Terminology A C2962 Seizure Seizure Sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin. C4876 Symptom C96388 NICHD Childhood Immunization Terminology A C29694 Inactivated Vaccine Inactivated Vaccine A preparation of killed microorganisms that is intended to prevent or treat an infectious disease by inducing active immunity to the causative microorganism. C923 Vaccine C96388 NICHD Childhood Immunization Terminology A C2978 Cyst Cyst A sac-like closed membranous structure that may be empty or contain fluid or amorphous material. C2991 Disease or Disorder C96388 NICHD Childhood Immunization Terminology A C2987 Diarrhea Diarrhea A condition of frequent and watery bowel movements. C4876 Symptom C96388 NICHD Childhood Immunization Terminology A C29888 Mumps Mumps A contagious viral infection caused by the mumps virus. Symptoms include swollen and tender parotid glands, fever, muscle aches and fatigue. Due to vaccination programs, mumps has become a rare disease. C96411 Childhood Viral Disease C96388 NICHD Childhood Immunization Terminology A C2990 Gastrointestinal Disorder Gastrointestinal Disorder A non-neoplastic or neoplastic disorder that affects the gastrointestinal tract, anus, liver, biliary system, and pancreas. C2991 Disease or Disorder C96388 NICHD Childhood Immunization Terminology A C2991 Disease or Disorder Disease or Disorder Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function. C90259 NICHD Pediatric Terminology C96388 NICHD Childhood Immunization Terminology A C3038 Fever Fever The elevation of the body's temperature above the upper limit of normal, usually taken as 37.7 degrees C. C4876 Symptom C96388 NICHD Childhood Immunization Terminology A C307 Biological Agent Biologic Agent Biotechnology-derived pharmaceutical agents made from living organisms or their products. Includes recombinant proteins, monoclonal antibodies, and nucleic acids. C1909 Pharmacologic Substance C96388 NICHD Childhood Immunization Terminology A C3096 Hepatitis A Infection Hepatitis A Acute inflammation of the liver caused by the hepatitis A virus. It is highly contagious and usually contracted through close contact with an infected individual or their feces, contaminated food or water. C3439 Viral Disease C96388 NICHD Childhood Immunization Terminology A C3097 Hepatitis B Infection Hepatitis B A viral infection caused by the hepatitis B virus. C3439 Viral Disease C96388 NICHD Childhood Immunization Terminology A C3114 Hypersensitivity Allergic Reaction A local or general reaction of an organism following contact with a specific allergen to which it has been previously exposed and to which it has become sensitized. C4876 Symptom C96388 NICHD Childhood Immunization Terminology A C3262 Neoplasm Neoplasm A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias. C2991 Disease or Disorder C96388 NICHD Childhood Immunization Terminology A C3303 Pain Pain The sensation of discomfort, distress, or agony, resulting from the stimulation of specialized nerve endings. C4876 Symptom C96388 NICHD Childhood Immunization Terminology A C3333 Pneumonia Pneumonia An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, due to infections (viruses, fungi, mycoplasma, or bacteria), treatment (e.g. radiation), or exposure (inhalation) to chemicals. Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness. C26871 Respiratory System Disorder C96388 NICHD Childhood Immunization Terminology A C3364 Septicemia Sepsis The presence of pathogenic microorganisms in the blood stream causing a rapidly progressing systemic reaction that may lead to shock. Symptoms include fever, chills, tachycardia, and increased respiratory rate. It is a medical emergency that requires urgent medical attention. C2890 Bacterial Disease C96388 NICHD Childhood Immunization Terminology A C3439 Viral Infection Viral Disease Viral Infection Any disease caused by a virus. C26726 Infectious Disease C96388 NICHD Childhood Immunization Terminology A C3442 Vomiting Vomiting The reflex act of ejecting the contents of the stomach through the mouth. C4876 Symptom C96388 NICHD Childhood Immunization Terminology A C34541 Diphtheria Diphtheria A Gram-positive bacterial infection caused by Corynebacterium diphtheria. It usually involves the oral cavity, pharynx, and nasal cavity. Patients develop pseudomembranes in the affected areas and manifest signs and symptoms of an upper respiratory infection. The diphtheria toxin may cause myocarditis, polyneuritis, and other systemic effects. C2890 Bacterial Disease C96388 NICHD Childhood Immunization Terminology A C34632 Gastroenteritis Gastroenteritis An inflammatory disorder that affects the upper and lower gastrointestinal tract. Most commonly, this is attributed to viruses; however bacteria, parasites or adverse reactions can also be the culprit. Symptoms include acute diarrhea and vomiting. C2990 Gastrointestinal Disorder C96388 NICHD Childhood Immunization Terminology A C34797 Malaria Malaria A protozoan infection caused by the genus Plasmodium. There are four species of Plasmodium that can infect humans: Plasmodium falciparum, vivax, ovale, and malariae. It is transmitted to humans by infected mosquitoes. Signs and symptoms include paroxysmal high fever, sweating, chills, and anemia. C27864 Parasitic Disease C96388 NICHD Childhood Immunization Terminology A C35089 Typhoid Fever Typhoid Fever A bacterial infectious disorder contracted by consumption of food or drink contaminated with Salmonella typhi. This disorder is common in developing countries and can be treated with antibiotics. C2890 Bacterial Disease C96388 NICHD Childhood Immunization Terminology A C35470 Behavior-Related Disorder Behavioral Disorder A specific behavioral problem that occurs in persistent patterns and characteristic clusters and that causes clinically significant impairment. C2991 Disease or Disorder C96388 NICHD Childhood Immunization Terminology A C35547 Yellow Fever Virus Infection Yellow Fever Virus Infection A viral infection caused by a flavivirus called yellow fever virus. It is transmitted to humans from infected mosquitoes. The signs and symptoms range from a mild febrile illness to liver damage with jaundice and hemorrhages. C3439 Viral Disease C96388 NICHD Childhood Immunization Terminology A C35550 Acute Poliomyelitis Poliomyelitis Polio An acute infectious disorder that affects the nervous system. It is caused by the poliovirus. The virus spreads by direct contact, and can be prevented by prophylaxis with the polio vaccine. C96411 Childhood Viral Disease C96388 NICHD Childhood Immunization Terminology A C35731 Hearing Loss Hearing Loss A partial or complete loss of hearing in one or both ears. It is classified as conductive, sensory, or central. C63711 Sensory Disorder C96388 NICHD Childhood Immunization Terminology A C3724 Cystic Hygroma Cystic Hygroma Cystic Lymphangioma A benign lymphatic neoplasm usually arising from the neck and characterized by cystic dilation of the lymphatic vessels. C2978 Cyst C96388 NICHD Childhood Immunization Terminology A C3782 Cervical Intraepithelial Neoplasia Cervical Intraepithelial Neoplasia Squamous or glandular intraepithelial neoplasia that affects the cervical mucosal epithelium. There is no evidence of stromal invasion. According to the degree of cellular atypia and the associated architectural changes, it is classified as low or high grade. C3262 Neoplasm C96388 NICHD Childhood Immunization Terminology A C37928 Confusion Confusion A mental state characterized by a lack of clear and orderly thought and behavior. C4876 Symptom C96388 NICHD Childhood Immunization Terminology A C38114 Route of Administration Route of Administration Designation of the part of the body through which or into which, or the way in which, the medicinal product is intended to be introduced. In some cases a medicinal product can be intended for more than one route and/or method of administration. C16847 Technique C96388 NICHD Childhood Immunization Terminology A C38141 Pneumococcal 7-Valent Conjugate Vaccine Pneumococcal 7-Valent Conjugate Vaccine An active immunizing agent used to prevent infection by the bacterium Streptococcus pneumoniae. Pneumococcal 7-valent conjugate vaccine consists of a solution of saccharides of the capsular antigens of Streptococcus serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F individually conjugated to diphtheria CRM 197 protein. C97123 Pneumococcal Conjugate Vaccine C96388 NICHD Childhood Immunization Terminology A C38276 Intravenous Route of Administration Intravenous Route of Administration Administration of a drug within or into a vein or veins. Introduction of the drug directly into venous circulation results in 100% bioavailability due to an absence of the absorption phase, provides a precise and continuous mode of drug therapy, especially for drugs with a narrow therapeutic index. C38291 Parenteral Route of Administration C96388 NICHD Childhood Immunization Terminology A C38284 Nasal Route of Administration Nasal Route of Administration Administration of a drug by the way of the nose. This often results in systemic action of the agent due to absorption through the nasal mucosa. The richly supplied vascular nature of the nasal mucosa coupled with its high drug permeation makes the nasal route of administration attractive for many drugs, including proteins and peptides. C38114 Route of Administration C96388 NICHD Childhood Immunization Terminology A C38288 Oral Route of Administration Oral Route of Administration The introduction of a substance to the mouth or into the gastrointestinal tract by the way of the mouth, usually for systemic action. It is the most common, convenient, and usually the safest and least expensive route of drug administration, but it uses the most complicated pathway to the tissues and bioavailability varies. The disadvantages of method are hepatic first pass metabolism and enzymatic degradation of the drug within the gastrointestinal tract. This prohibits oral administration of certain classes of drugs especially peptides and proteins. C38114 Route of Administration C96388 NICHD Childhood Immunization Terminology A C38291 Parenteral Route of Administration Parenteral Route of Administration Administration of a substance by some means other than through the gastrointestinal tract: usually through injection, infusion, or implantation. Predominantly, the drug action is systemic, but in some cases, it is confined to local area. C38114 Route of Administration C96388 NICHD Childhood Immunization Terminology A C38299 Subcutaneous Route of Administration Subcutaneous Route of Administration Drug administration beneath the skin. It provides for relatively slow, sustained release of the drug. The rate of absorption into the blood is perfusion-limited, proportional to the amount of drug at the site and can be enhanced by chemical or physical stimulation of blood flow. Subcutaneous administration minimizes the risks associated with intravascular injection: for subcutaneous infusions, external and implantable pumps are used. C38291 Parenteral Route of Administration C96388 NICHD Childhood Immunization Terminology A C39594 Skin Rash Skin Rash Any change in the skin which affects its appearance or texture. A rash may be localized to one part of the body, or affect all the skin. Rashes may cause the skin to change color, itch, become warm, bumpy, dry, cracked or blistered, swell and may be painful. C4876 Symptom C96388 NICHD Childhood Immunization Terminology A C4077 Redness Redness Coloration of the skin; sign of inflammation C4876 Symptom C96388 NICHD Childhood Immunization Terminology A C53482 Influenza Influenza Flu An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system. C3439 Viral Disease C96388 NICHD Childhood Immunization Terminology A C62651 Allergen Allergen A substance that elicits an allergic reaction. C45306 Substance C96388 NICHD Childhood Immunization Terminology A C62761 Attenuated Bacteria Vaccine Attenuated Live Bacterial Vaccine Any vaccine created by reducing the virulence of bacteria but still keeping the bacteria viable (live). In the production of an attenuated vaccine, the infectious agent is altered so that it becomes harmless or less virulent. This is in contrast to those vaccines produced by "killing" the pathogen (inactivated vaccine). C97116 Attenuated Live Vaccine C96388 NICHD Childhood Immunization Terminology A C63711 Neurosensory Disorder Sensory Disorder An interruption or alteration in the sensory activity or functions of the nervous system. C2991 Disease or Disorder C96388 NICHD Childhood Immunization Terminology A C71091 Human Herpesvirus 3 Varicella-Zoster Virus An icosahedral, enveloped virus containing a single molecule of linear double-stranded DNA of 125000 nucleotides that infects only humans. It is the causative agent of chickenpox and shingles. C14283 Virus C96388 NICHD Childhood Immunization Terminology A C76205 Bordetella pertussis Bordetella pertussis A species of bacteria within the phylum Proteobacteria consisting of gram-negative aerobic coccobacillus that are the causative agent of pertussis. C14187 Bacteria C96388 NICHD Childhood Immunization Terminology A C77199 Rotavirus Rotavirus A genus of double stranded RNA viruses that carry 11 unique double helix molecules of RNA that encode one or two proteins each. The RNA is surrounded by a three-layered icosahedral protein capsid. Viral particles are up to 76.5 nm in diameter and are not enveloped. C14283 Virus C96388 NICHD Childhood Immunization Terminology A C80444 H1N1 Influenza H1N1 Influenza Swine flu An acute viral respiratory infection caused by a strain of influenza virus which is endemic in swine (pigs). Rarely reported in humans prior to 2009, the disease is caused by a mutated strain of swine influenza A (H1N1) virus. It is highly contagious and spreads mainly through coughing and sneezing. Signs and symptoms include fever, chills, coughing, sore throat headache, muscle ache, and generalized weakness. Antiviral medications are most effective in the first two days of the illness. C53482 Influenza C96388 NICHD Childhood Immunization Terminology A C84392 Mental Retardation Mental Retardation A developmental disorder characterized by less than average intelligence and significant limitations in adaptive behavior with onset before the age of 18. C92190 Childhood Mental Disorder C96388 NICHD Childhood Immunization Terminology A C85051 Rubella Infection Rubella Infection German Measles A viral infection caused by the rubella virus. It is initially manifested with flu-like symptoms that last one or two days, followed by the development of a characteristic red rash which lasts from one to five days. The rash first appears in the neck and face. It subsequently spreads to the rest of the body. C3439 Viral Disease C96388 NICHD Childhood Immunization Terminology A C85185 Tetanus Tetanus A serious infectious disorder that follows wound contamination by the Gram-positive bacterium Clostridium tetani. The bacteria produce a neurotoxin called tetanospasmin, which causes muscle spasm in the jaw and other anatomic sites. C2890 Bacterial Disease C96388 NICHD Childhood Immunization Terminology A C86605 Neisseria meningitidis Neisseria meningitidis A gram negative diplococcal bacterium that is a causative agent for meningitis and other meningococcal diseases. C14187 Bacteria C96388 NICHD Childhood Immunization Terminology A C9011 Dermoid Cyst Dermoid Cyst A mature teratoma characterized by the presence of a cyst which is lined by mature tissue resembling the epidermis and the epidermal appendages. It occurs in the ovary, testis, and extragonadal sites including central nervous system and skin. C2978 Cyst C96388 NICHD Childhood Immunization Terminology A C9039 Cervical Carcinoma Cervical Carcinoma A carcinoma arising from either the exocervical squamous epithelium or the endocervical glandular epithelium. The major histologic types of cervical carcinoma are: squamous carcinoma, adenocarcinoma, adenosquamous carcinoma, adenoid cystic carcinoma and undifferentiated carcinoma. C3262 Neoplasm C96388 NICHD Childhood Immunization Terminology A C91715 Inactivated Poliovirus Vaccine Inactivated Poliovirus Vaccine A vaccine consisting of inactivated poliovirus (IPV) types 1,2 and 3, with active immunizing activity against poliomyelitis. Upon intramuscular vaccination, inactivated poliovirus vaccine (IPV) activates the immune system to develop antibodies against polioviruses. C29694 Inactivated Vaccine C96388 NICHD Childhood Immunization Terminology A C91717 Diphtheria Toxoid/Tetanus Toxoid/Acellular Pertussis Vaccine Adsorbed Diphtheria Toxoid/Tetanus Toxoid/Acellular Pertussis Vaccine DTP vaccine A vaccine containing detoxified tetanus toxoid, detoxified diphtheria toxoid and acellular pertussis antigens, adsorbed on aluminum phosphate, with active immunizing activity against diphtheria, tetanus and pertussis. The acellular pertussis vaccine components, produced by Bordetella pertussis, are detoxified pertussis toxin (PT), filamentous hemagglutinin (FHA), pertactin (PRN) and fimbriae types 2 and 3 (FIM). Intramuscular injection with this vaccine activates the immune system to develop antibodies against tetanus toxin, diphtheria toxin and B. pertussis antigens. C2848 Polyvalent Vaccine C96388 NICHD Childhood Immunization Terminology A C91718 Diphtheria Toxoid/Tetanus Toxoid Vaccine Adsorbed Diphtheria Toxoid/Tetanus Toxoid Vaccine Adsorbed A vaccine containing detoxified tetanus toxoid and detoxified diphtheria toxoid adsorbed on aluminum phosphate with active immunizing activity against diphtheria and tetanus. Intramuscular injection with this vaccine activates the immune system to develop antibodies against tetanus toxin and diphtheria toxin. C96398 Toxoid Vaccine C96388 NICHD Childhood Immunization Terminology A C9229 Systemic Disease Systemic Disorder A clinical course finding indicating that a disease presents with systemic manifestations. C2991 Disease or Disorder C96388 NICHD Childhood Immunization Terminology A C923 Vaccine Vaccine Preparations containing substances with antigenic properties administered to activate the immune system, thereby inducing an immune response. Vaccines range from inactivated or attenuated microorganisms (bacteria and viruses), enhanced autologous tumor cells, tumor antigens or epitopes that are used to elicit host immune responses. Vaccines are used for the prevention, amelioration, or treatment of infectious diseases and cancer. C307 Biologic Agent C96388 NICHD Childhood Immunization Terminology A C92872 Rubella Immunization Rubella Immunization The administration of a live attenuated viral vaccine to prevent rubella infection. C15258 Immunization C96388 NICHD Childhood Immunization Terminology A C92915 Varicella Zoster Virus Immunization Chickenpox Immunization The administration of a live attenuated viral vaccine to prevent herpes zoster infection. C15258 Immunization C96388 NICHD Childhood Immunization Terminology A C92947 Rh Immune Globulin Administration Rh Immune Globulin Administration Rho(D) Immune Globulin Administration The administration of Rh Immune Globulin to a pregnant mother to ameliorate the effects of conflicting Rh factors during pregnancy. C15843 Preventive Intervention C96388 NICHD Childhood Immunization Terminology A C96391 Meningococcal Conjugate Vaccine MCV4 Meningococcal Conjugate Vaccine MCV-4 A conjugate vaccine of meningococcal polysaccharide used for active immunization against invasive meningococcal disease caused by Neisseria meningiditis serogroups A, C, Y, and W-135. C1455 Conjugate Vaccine C96388 NICHD Childhood Immunization Terminology A C96394 Rotavirus Vaccine Rotavirus Vaccine A viral vaccine that prevents against rotavirus infection, the leading cause of severe acute gastroenteritis. C1920 Attenuated Live Virus Vaccine C96388 NICHD Childhood Immunization Terminology A C96395 Varicella Vaccine Varicella Vaccine Chickenpox Vaccine|Shingles Vaccine A live attenuated virus vaccine used to prevent chickenpox and shingles, which is caused by varicella-zoster virus (VZV). C1920 Attenuated Live Virus Vaccine C96388 NICHD Childhood Immunization Terminology A C96396 Yellow Fever Vaccine Yellow Fever Vaccine A live, attenuated viral vaccine to prevent yellow fever, endemic to parts of Africa and South America. C1920 Attenuated Live Virus Vaccine C96388 NICHD Childhood Immunization Terminology A C96398 Toxoid Vaccine Toxoid Vaccine Any vaccine that contains an inactivated toxic substance used for disease prophylaxis or to vaccinate against snake bites. C923 Vaccine C96388 NICHD Childhood Immunization Terminology A C96401 Oral Polio Vaccine Oral Polio Vaccine A vaccine that contains live attenuated polio virus. It is administered orally as polio prophylaxis in many areas of the world, but not in the U.S. since 2000. C1920 Attenuated Live Virus Vaccine C96388 NICHD Childhood Immunization Terminology A C96402 Live Attenuated Influenza Vaccine Live Attenuated Influenza Vaccine Nasal Spray Flu Vaccine A vaccine that contains live attenuated influenza virus (LAIV) particles. This vaccine is administered intranasally for influenza prophylaxis. Not all populations are good candidates for LAIV; the very young, elderly, asthmatics and those with health impaired may be better treated with the trivalent inactivated vaccine that is administered intramuscularly. C1920 Attenuated Live Virus Vaccine C96388 NICHD Childhood Immunization Terminology A C96403 Measles/Mumps/Rubella Vaccine Measles Mumps Rubella Vaccine A trivalent vaccine containing live attenuated viruses that can cause measles, mumps and rubella. It is an injection administered subcutaneously in two separate doses. C1920 Attenuated Live Virus Vaccine C96388 NICHD Childhood Immunization Terminology A C96405 Tetanus and Diphtheria Toxoids Adsorbed Tetanus and Diphtheria Toxoids Adsorbed A sterile, intramuscular suspension of alum (aluminum potassium sulfate)-precipitated toxoids indicated for active immunization for the prevention of tetanus and diphtheria for use in persons 7 years of age or older. C96398 Toxoid Vaccine C96388 NICHD Childhood Immunization Terminology A C96406 Rubeola Infection Measles Rubeola A highly contagious viral infection caused by the measles virus. Symptoms appear 8-12 days after exposure and include a rash, cough, fever and muscle pains that can last 4-7 days. Measles vaccines are available to provide prophylaxis, usually combined with mumps and rubella vaccines (MMR). C96411 Childhood Viral Disease C96388 NICHD Childhood Immunization Terminology A C96408 Influenza Vaccination Influenza Vaccination The administration of live or attenuated influenza virus for the prophylaxis of influenza. C15258 Immunization C96388 NICHD Childhood Immunization Terminology A C96409 Polio Vaccination Polio Vaccination The administration a series of either live or inactivated poliovirus for the prophylaxis of poliomyelitis. C15258 Immunization C96388 NICHD Childhood Immunization Terminology A C96411 Pediatric Viral Infection Childhood Viral Disease A viral infection that occurs during childhood. C89328 Pediatric Disease or Disorder C3439 Viral Disease C96388 NICHD Childhood Immunization Terminology A C96412 Brain Developmental Abnormality Brain Development Abnormality A group of congenital or acquired disorders that affect the normal development of the brain. C89338 Neurodevelopmental Disorder C96388 NICHD Childhood Immunization Terminology A C96413 Brain Disorder Brain Disorder A non-neoplastic or neoplastic disorder that affects the brain. C2934 Central Nervous System Disorder C96388 NICHD Childhood Immunization Terminology A C96519 Meningococcal Polysaccharide Vaccine MPSV4 Meningococcal Polysaccharide Vaccine MPSV-4 A polysaccharide vaccine used to prevent contraction of meningococcal meningitis. C97125 Polysaccharide Vaccine C96388 NICHD Childhood Immunization Terminology A C97116 Attenuated Live Vaccine Attenuated Live Vaccine Any vaccine created by reducing the virulence of the infectious agent but still keeping the agent viable (live). In the production of an attenuated vaccine, the infectious agent is altered so that it becomes harmless or less virulent. This is in contrast to those vaccines produced by killing the pathogen (inactivated vaccine). C923 Vaccine C96388 NICHD Childhood Immunization Terminology A C97120 Pneumococcal 10-valent Conjugate Vaccine Pneumococcal 10-valent Conjugate Vaccine An active immunizing vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. It is indicated for disease caused by serotypes 1, 5, 4, 6B, 7, 9V, 14, 18C, 19F, and 23F. C97123 Pneumococcal Conjugate Vaccine C96388 NICHD Childhood Immunization Terminology A C97121 Pneumococcal 13-valent Conjugate Vaccine Pneumococcal 13-valent Conjugate Vaccine An active immunizing vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. It is indicated for disease caused by serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F. It can also be used to prevent against otitis media by serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F. C97123 Pneumococcal Conjugate Vaccine C96388 NICHD Childhood Immunization Terminology A C97122 Diphtheria Toxoid/Tetanus Toxoid/Inactivated Pertussis Vaccine Diphtheria Toxoid/Tetanus Toxoid/Inactivated Pertussis Vaccine DTP A vaccine containing detoxified tetanus toxoid, detoxified diphtheria toxoid and inactivated pertussis antigens. C2848 Polyvalent Vaccine C96388 NICHD Childhood Immunization Terminology A C97123 Pneumococcal Conjugate Vaccine Pneumococcal Conjugate Vaccine An active immunizing vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. It consists of a solution of saccharides of the capsular antigens of Streptococcus serotypes individually conjugated to proteins. C1455 Conjugate Vaccine C96388 NICHD Childhood Immunization Terminology A C97125 Polysaccharide Vaccine Polysaccharide Vaccine A category of vaccines that use the extracted and purified outer polysaccharide coat of the particular bacteria. C923 Vaccine C96388 NICHD Childhood Immunization Terminology A C97126 Ty21a Typhoid Vaccine Ty21a Typhoid Vaccine A live attenuated oral virus vaccine used to prevent typhoid, which is caused by Salmonella typhi. C62761 Attenuated Live Bacterial Vaccine C96388 NICHD Childhood Immunization Terminology A C97127 Vi Capsular Polysaccharide Typhoid Vaccine Vi Capsular Polysaccharide Typhoid Vaccine A live attenuated injectable virus vaccine used to prevent typhoid, which is caused by Salmonella typhi. C97125 Polysaccharide Vaccine C96388 NICHD Childhood Immunization Terminology A C97132 Chicken Pox Infection Chicken Pox A contagious childhood disorder caused by the varicella zoster virus. It is transmitted via respiratory secretions and contact with chickenpox blister contents. It presents with a vesicular skin rush, usually associated with fever, headache, and myalgias. The pruritic fluid-filled vesicles occur 10-21 days after exposure and last for 3-4 days. An additional 3-4 days of malaise follows before the affected individual feels better. An individual is contagious 1-2 days prior to the appearance of the blisters until all blisters are crusted over. Generally, healthy individuals recover without complications. C96411 Childhood Viral Disease C96388 NICHD Childhood Immunization Terminology A C15329 Surgical Procedure Surgical Procedure A diagnostic or treatment procedure performed by manual and/or instrumental means, often involving an incision and the removal or replacement of a diseased organ or tissue; of or relating to or involving or used in surgery or requiring or amenable to treatment by surgery. C25218 Intervention or Procedure C97150 NICHD Neurological Development Terminology A C15332 Gynecological Surgical Procedure Gynecologic Surgical Procedure Surgery performed on the female reproductive system. C15329 Surgical Procedure C97150 NICHD Neurological Development Terminology A C15429 Research Activity Research Activity Systematic investigation into a subject in order to discover facts, establish or revise a theory, or develop a plan of action based on the facts discovered. C16205 Healthcare Activity C97150 NICHD Neurological Development Terminology A C26323 Hematologic and Lymphocytic Disorder Hematological Disorder A neoplastic or non-neoplastic disorder that affects the production and proliferation of the hematopoietic cells including lymphoid cells, the synthesis of hemoglobin, and/or the mechanisms of coagulation. C2991 Disease or Disorder C97150 NICHD Neurological Development Terminology A C26739 Sensorineural Deafness Sensorineural Hearing Loss Hearing loss caused by a problem in the inner ear or auditory nerve. A sensorineural loss often affects a person’s ability to hear some frequencies more than others. This means that sounds may be appear distorted, even with the use of a hearing aid. Sensorineural losses can range from mild to profound. C35731 Hearing Loss C97150 NICHD Neurological Development Terminology A C26835 Nervous System Disorder Neurologic Disorder A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves. C2991 Disease or Disorder C97150 NICHD Neurological Development Terminology A C26871 Respiratory Disorder Respiratory System Disorder A non-neoplastic or neoplastic disorder that affects the tracheobronchial tree and/or the lung parenchyma. Representative examples include infections, carcinomas, and lymphomas. C2991 Disease or Disorder C97150 NICHD Neurological Development Terminology A C26920 Encephalopathy Encephalopathy A functional and/or structural disorder of the brain caused by diseases (e.g. liver disease, kidney disease), medications, chemicals, and injuries. C96413 Brain Disorder C97150 NICHD Neurological Development Terminology A C27019 Male Reproductive System Disorder Male Reproductive System Disorder A non-neoplastic or neoplastic disorder that affects the male genital system. Representative examples of non-neoplastic disorders include infection, testicular torsion, and undescended testis. Representative examples of neoplastic disorders include germ cell tumors, carcinoma, lymphoma, and sarcoma. C4875 Reproductive System Disorder C97150 NICHD Neurological Development Terminology A C27020 Female Reproductive System Disorder Female Reproductive System Disorder A non-neoplastic or neoplastic disorder that affects the female genital system. Representative examples of non-neoplastic disorders include infection, endometriosis, and adenomyosis. Representative examples of neoplastic disorders include germ cell tumors, carcinoma, lymphoma, and sarcoma. C4875 Reproductive System Disorder C97150 NICHD Neurological Development Terminology A C27560 Neonatal Respiratory Distress Syndrome Neonatal Respiratory Distress Syndrome A condition of the newborn marked by dyspnea with cyanosis, most frequently occurring in premature infants, children of diabetic mothers and infants delivered by cesarean section, and sometimes with no predisposing cause. C97173 Congenital Abnormality of the Respiratory System C97150 NICHD Neurological Development Terminology A C27561 Respiratory Distress Syndrome Respiratory Distress Syndrome A group of conditions characterized by failure of normal respiration caused by lack of lung surfactant. C26871 Respiratory System Disorder C97150 NICHD Neurological Development Terminology A C27574 Connective and Soft Tissue Disorder Musculoskeletal System Disorder Any deviation from the normal structure or function of the musculoskeletal or connective tissue that is manifested by a characteristic set of symptoms and signs. C2991 Disease or Disorder C97150 NICHD Neurological Development Terminology A C27645 Conductive Hearing Loss Conductive Hearing Loss Hearing loss caused by a problem in the outer ear or middle ear. Conductive losses usually affect all frequencies to the same degree. These losses are not usually severe. C35731 Hearing Loss C97150 NICHD Neurological Development Terminology A C2878 Anxiety Disorder Anxiety Disorder A category of psychiatric disorders which are characterized by anxious feelings or fear often accompanied by physical symptoms associated with anxiety. C2893 Psychiatric Disorder C97150 NICHD Neurological Development Terminology A C2931 Cardiovascular Disorder Cardiovascular Disorder A non-neoplastic or neoplastic disorder affecting the heart or the vessels (arteries, veins and lymph vessels). Representative examples of non-neoplastic cardiovascular disorders are endocarditis and hypertension. Representative examples of neoplastic cardiovascular disorders are endocardial myxoma and angiosarcoma. C2991 Disease or Disorder C97150 NICHD Neurological Development Terminology A C2934 Central Nervous System Disorder Central Nervous System Disorder A non-neoplastic or neoplastic disorder which affects the brain and/or spinal cord. C26835 Neurologic Disorder C97150 NICHD Neurological Development Terminology A C3009 Endocrine Disorder Endocrine System Disorder Any deviation from the normal structure or function of the endocrine system that is manifested by a characteristic set of symptoms and signs. C2991 Disease or Disorder C97150 NICHD Neurological Development Terminology A C3020 Epilepsy Epilepsy A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions. C96413 Brain Disorder C97150 NICHD Neurological Development Terminology A C3371 Skin Disorder Integumentary System Disorder Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs. C2991 Disease or Disorder C97150 NICHD Neurological Development Terminology A C3389 Post-Traumatic Stress Disorder Post-Traumatic Stress Disorder An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by intrusive recurring thoughts or images of the traumatic event; avoidance of anything associated with the event; a state of hyperarousal and diminished emotional responsiveness. These symptoms are present for at least one month and the disorder is usually long-term. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology A C34362 Agoraphobia Agoraphobia An anxiety disorder characterized by an intense, irrational fear of venturing out into open places or situations in which help (or escape) might not be available should excessive anxiety or panic symptoms develop. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology A C34387 Anorexia Nervosa Anorexia Nervosa A disorder most often seen in adolescent females characterized by a refusal to maintain a minimally normal body weight, an intense fear of gaining weight, a disturbance in body image, and, in postmenarcheal females, the development of amenorrhea. C89332 Eating Disorder C97150 NICHD Neurological Development Terminology A C34423 Bipolar Disorder Bipolar Disorder A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence. C2893 Psychiatric Disorder C97150 NICHD Neurological Development Terminology A C34440 Bulimia Bulimia Nervosa A disorder characterized by recurrent episodes of binge-eating over which the individual feels a lack of control; these episodes of binge-eating are followed by recurrent compensatory behavior to prevent weight gain, usually self-induced vomiting. In addition, self-evaluation is unduly influenced by body image. C89332 Eating Disorder C97150 NICHD Neurological Development Terminology A C34460 Cerebral Palsy Cerebral Palsy A group of disorders affecting the development of movement and posture, often accompanied by disturbances of sensation, perception, cognition, and behavior. It results from damage to the fetal or infant brain. C26835 Neurologic Disorder C89328 Pediatric Disease or Disorder C97150 NICHD Neurological Development Terminology A C34527 Demyelinating Disorder Demyelinating Disorder A broad group of disorders that affect the myelin sheaths that cover the neurons. Myelin sheathes cover neuronal axons in the central and peripheral nervous system and function to increase travelling impulse speeds. Disruption of this sheath impairs neuronal transmission and can result in disorders such as multiple sclerosis and Guillain-Barre syndrome, among others. C26835 Neurologic Disorder C97150 NICHD Neurological Development Terminology A C34662 Central Hearing Loss Central Hearing Loss Hearing loss caused by a problem along the pathway from the inner ear to the auditory region of the brain or in the brain itself. C35731 Hearing Loss C97150 NICHD Neurological Development Terminology A C34927 Social Phobia Social Anxiety Disorder An anxiety disorder characterized by an intense, irrational fear of one or more social or performance situations in which the individual believes that he or she will be scrutinized by others. Exposure to social situations immediately provokes an anxiety response. In adults, the social phobia is recognized as excessive or unreasonable. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology A C34982 Retrolental Fibroplasia Retinopathy of Prematurity A bilateral retinopathy characterized by neovascularization, scarring, retinal detachment, and eventually blindness. It may be mild or severe. It occurs in babies born prematurely. Causes include oxygen toxicity and hypoxia. C97172 Congenital Abnormality of the Nervous System C97150 NICHD Neurological Development Terminology A C35004 Childhood Schizophrenia Childhood Schizophrenia Schizophrenia occurring in childhood. C92190 Childhood Mental Disorder C97150 NICHD Neurological Development Terminology A C35014 Separation Anxiety Disorder Separation Anxiety Disorder An anxiety disorder characterized by recurrent excessive distress due to fear of separation from the home or from major attachment figures; the distress is developmentally inappropriate and causes impairment in social, academic, or other areas of functioning. C92190 Childhood Mental Disorder C97150 NICHD Neurological Development Terminology A C3507 Immune System Disorder Immunolymphatic System Disorder A disorder resulting from an abnormality in the immune system. -- 2003 C2991 Disease or Disorder C97150 NICHD Neurological Development Terminology A C35078 Tourette Syndrome Tourette's Syndrome A neurologic disorder caused by defective metabolism of the neurotransmitters in the brain. It is characterized by repeated involuntary movements (motor tics) and uncontrollable vocal sounds (vocal tics). The symptoms are usually manifested before the age of eighteen. C96412 Brain Development Abnormality C97150 NICHD Neurological Development Terminology A C35107 Congenital Genitourinary Abnormality Congenital Abnormality of the Genitourinary System An abnormality of the genitourinary system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C97150 NICHD Neurological Development Terminology A C35126 Vision Disorder Vision Disorder Visual impairments limiting one or more of the basic functions of the eye: visual acuity, dark adaptation, color vision, or peripheral vision. These may result from eye diseases, optic nerve diseases, visual pathway diseases, occipital lobe diseases, ocular motility disorders' and other conditions. C63711 Sensory Disorder C97150 NICHD Neurological Development Terminology A C35275 Visual Cortex Disorder Visual Cortex Disorder Cortical Visual Impairment A vision disorder that results from damage of the part of the cerebral cortex that is involved in the processing of visual information. C35126 Vision Disorder C97150 NICHD Neurological Development Terminology A C35284 Specific Phobia Specific Phobia An anxiety disorder characterized by an intense, irrational fear cued by the presence or anticipation of a specific object or situation. Exposure to the phobic stimulus immediately provokes an anxiety response. In adults, the specific phobia is recognized as excessive or unreasonable. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology A C35470 Behavior-Related Disorder Behavioral Disorder A specific behavioral problem that occurs in persistent patterns and characteristic clusters and that causes clinically significant impairment. C2991 Disease or Disorder C97150 NICHD Neurological Development Terminology A C35729 Congenital Cardiovascular Abnormality Congenital Abnormality of the Circulatory System A heart or vascular abnormality which is inborn or present at birth. C2849 Congenital Abnormality C97150 NICHD Neurological Development Terminology A C35731 Hearing Loss Hearing Loss A partial or complete loss of hearing in one or both ears. It is classified as conductive, sensory, or central. C63711 Sensory Disorder C97150 NICHD Neurological Development Terminology A C42734 Contraceptive Device Contraceptive Device A device designed to prevent conception through local or systemic effect, such as a barrier contraceptive, an intrauterine device, or a means of preventing ovulation (e.g., birth control pill). C62103 Device C97150 NICHD Neurological Development Terminology A C4875 Reproductive System Disorder Reproductive System Disorder A non-neoplastic or neoplastic disorder that affects the male or female genital system. Representative examples of non-neoplastic disorders include infection, testicular torsion, endometriosis, and adenomyosis. Representative examples of neoplastic disorders include germ cell tumors, carcinoma, lymphoma, and sarcoma. C2991 Disease or Disorder C97150 NICHD Neurological Development Terminology A C5041 Speech Manifestations Speech Disorder A term referring to disorders characterized by the disruption of normal speech. It includes stuttering, lisps, dysarthria and voice disorders. C9229 Systemic Disorder C97150 NICHD Neurological Development Terminology A C50896 Intraventricular Brain Hemorrhage Intraventricular Hemorrhage Bleeding into the brain's ventricles. C2931 Cardiovascular Disorder C97150 NICHD Neurological Development Terminology A C63711 Neurosensory Disorder Sensory Disorder An interruption or alteration in the sensory activity or functions of the nervous system. C2991 Disease or Disorder C97150 NICHD Neurological Development Terminology A C70856 Observation Result Observational Result An outcome of observation represented as a text, qualitative, or quantitative parameter, code, image, graph, etc. C3367 Finding C97150 NICHD Neurological Development Terminology A C75488 Rett Syndrome Rett Syndrome A progressive neurologic disorder caused by mutations in the MECP2 gene on chromosome X. It almost exclusively affects girls. It is characterized by language and learning difficulties, poor communication skills, and repetitive hand motions. Other signs and symptoms include microcephaly, scoliosis, breathing abnormalities, and sleep disturbances. C97179 Pervasive Developmental Disorder C97150 NICHD Neurological Development Terminology A C81182 Measurement Device Measurement Device Any device used to determine the dimension of an object. C62103 Device C97150 NICHD Neurological Development Terminology A C84392 Mental Retardation Mental Retardation A developmental disorder characterized by less than average intelligence and significant limitations in adaptive behavior with onset before the age of 18. C92190 Childhood Mental Disorder C97150 NICHD Neurological Development Terminology A C84915 Necrotizing Enterocolitis Necrotizing Enterocolitis A serious, life-threatening disorder characterized by necrotic changes affecting portions of the small and large intestine. It is usually seen in neonates, particularly premature infants. Signs and symptoms include abdominal distention and tenderness, intestinal bleeding and ileus. It may lead to cardiovascular collapse and shock. C97171 Congenital Abnormality of the Digestive System C97150 NICHD Neurological Development Terminology A C88411 Obsessive Compulsive Disorder Obsessive-Compulsive Disorder A disorder characterized by the presence of persistent and recurrent irrational thoughts (obsessions), resulting in marked anxiety and repetitive excessive behaviors (compulsions) as a way to try to decrease that anxiety. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology A C88412 Autism Spectrum Disorder Autism Spectrum Disorder A spectrum of developmental disorders that includes autism, Asperger syndrome, and Rett syndrome. Signs and symptoms include poor communication skills, defective social interactions, and repetitive behaviors. C97179 Pervasive Developmental Disorder C97150 NICHD Neurological Development Terminology A C89332 Eating Disorder Eating Disorder A broad group of psychological disorders with abnormal eating behaviors leading to physiological effects from overeating or insufficient food intake. C2893 Psychiatric Disorder C97150 NICHD Neurological Development Terminology A C89337 Congenital Musculoskeletal Defect Congenital Abnormality of the Musculoskeletal System An abnormality of the musculoskeletal system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C97150 NICHD Neurological Development Terminology A C90599 Bronchopulmonary Dysplasia Bronchopulmonary Dysplasia A non-neoplastic lung disorder which develops in premature neonates who have been treated with oxygen and mechanical ventilation. C97173 Congenital Abnormality of the Respiratory System C97150 NICHD Neurological Development Terminology A C92190 Pediatric Psychiatric Disorder Childhood Mental Disorder A category of psychiatric disorders which includes disorders most commonly identified in infancy, childhood, or adolescence. C89328 Pediatric Disease or Disorder C97150 NICHD Neurological Development Terminology A C92561 Developmental Coordination Disorder Developmental coordination disorder Developmental Dyspraxia A disorder characterized by an impairment in the development of an individual's motor coordination skills; this impairment in motor development is not due to a medical condition. C89338 Neurodevelopmental Disorder C92190 Childhood Mental Disorder C97150 NICHD Neurological Development Terminology A C92569 Selective Mutism Selective Mutism A persistent failure to speak in certain social situations (i.e., school) where speaking is expected, despite speaking in other situations. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology A C92621 Acute Stress Disorder Acute Stress Disorder An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by dissociative symptoms; vivid recollections of the traumatic event; avoidance of stimuli associated with the traumatic event; and a constant state of hyperarousal for no more than one month. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology A C92622 Generalized Anxiety Disorder Generalized Anxiety Disorder An anxiety disorder characterized by excessive and difficult-to-control worry about a number of life situations. The worry is accompanied by restlessness, fatigue, inability to concentrate, irritability, muscle tension, and/or sleep disturbance and lasts for at least 6 months. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology A C96410 Dyslexia Dyslexia A learning disorder characterized by an impairment in processing written words. Reading difficulties can include distortions, omissions or substitutions of characters. Oral and silent reading difficulties can include faulty and slow comprehension. C89334 Learning Disorder C97150 NICHD Neurological Development Terminology A C96412 Brain Developmental Abnormality Brain Development Abnormality A group of congenital or acquired disorders that affect the normal development of the brain. C89338 Neurodevelopmental Disorder C97150 NICHD Neurological Development Terminology A C96413 Brain Disorder Brain Disorder A non-neoplastic or neoplastic disorder that affects the brain. C2934 Central Nervous System Disorder C97150 NICHD Neurological Development Terminology A C97109 Blindness Blindness The lack of vision. It is caused by neurological or physiological factors. C35126 Vision Disorder C97150 NICHD Neurological Development Terminology A C97151 Systemic Congenital Disorder Systemic Congenital Disorder An inherited disorder that presents with systemic manifestations. C2849 Congenital Abnormality C97150 NICHD Neurological Development Terminology A C97155 Language Disorder Language Disorder A category of disorders characterized by an impairment in the development of an individual's language capabilities, which is in contrast to his/her non-verbal intellect. C92190 Childhood Mental Disorder C97150 NICHD Neurological Development Terminology A C97159 Asperger Syndrome Asperger Syndrome A disorder most often diagnosed in the pediatric years in which the individual displays marked impairment in social interaction and a repetitive, stereotyped pattern of behavior. The individual, however, displays no delay in language or cognitive development, which differentiates Asperger Syndrome from autism. C88412 Autism Spectrum Disorder C97150 NICHD Neurological Development Terminology A C97160 Attention Deficit Hyperactivity Disorder Attention Deficit Hyperactivity Disorder A disorder characterized by a marked pattern of inattention and/or hyperactivity-impulsivity that is inconsistent with developmental level and clearly interferes with functioning in at least two settings (e.g. at home and at school). At least some of the symptoms must be present before the age of 7 years. C35470 Behavioral Disorder C97150 NICHD Neurological Development Terminology A C97161 Autism Autism A disorder characterized by marked impairments in social interaction and communication accompanied by a pattern of repetitive, stereotyped behaviors and activities. Developmental delays in social interaction and language surface prior to age 3 years. C88412 Autism Spectrum Disorder C97150 NICHD Neurological Development Terminology A C97162 Binge Eating Disorder Binge Eating Disorder A disorder characterized by recurrent episodes of binge-eating over which the individual feels a lack of control and a sense of disgust and shame; unlike bulimia, however, there is no attempt to compensate for the binge-eating through vomiting or fasting. C89332 Eating Disorder C97150 NICHD Neurological Development Terminology A C97163 Childhood Depression Childhood Depression Similar to depression in adults, childhood depression is characterized by a prolonged depressed or irritable mood accompanied by a significant loss of interest in activities, changes in appetite or sleep, decreased energy, feelings of worthlessness, and/or recurrent thoughts of death or suicide. C92190 Childhood Mental Disorder C97150 NICHD Neurological Development Terminology A C97164 Childhood Disintegrative Disorder Childhood Disintegrative Disorder A pediatric disorder characterized by normal development for at least the first two years of life followed by a severe regression in language, social interaction, bowel or bladder control, and/or motor skills. The affected individual may also exhibit repetitive and stereotyped patterns of behavior similar to autism. C97179 Pervasive Developmental Disorder C97150 NICHD Neurological Development Terminology A C97165 Dyscalculia Dyscalculia A wide group of related learning disorders characterized by difficulties with mathematics and manipulating numbers; the difficulty with math may be caused or exacerbated by visuo-spatial or language processing difficulties. C89334 Learning Disorder C97150 NICHD Neurological Development Terminology A C97166 Echolalia Echolalia A symptom of neurologic or psychiatric dysfunction in which the individual involuntarily and meaninglessly repeats a recently heard word, series of words, or a song. C97170 Central Auditory Processing Disorder C97150 NICHD Neurological Development Terminology A C97167 Anemia of Prematurity Anemia of Prematurity A blood disorder characterized by low hemoglobin levels in premature neonates that usually spontaneously resolves within 3-6 months post birth. A combination of factors including the transition from the liver to the bone marrow for erythropoiesis in a neonate, blood loss experienced during delivery, the shortened life span of fetal blood cells, and an acclimation to a relatively hyperoxic environment outside the womb can predispose a neonate to this condition. C35729 Congenital Abnormality of the Circulatory System C97150 NICHD Neurological Development Terminology A C97168 Ataxic Cerebral Palsy Ataxic Cerebral Palsy The least common subtype of cerebral palsy, in which the individual displays hypotonia, a loss of motor coordination, and an intention tremor. Individuals with ataxic cerebral palsy walk very unsteadily, with a wide-based gait. C34460 Cerebral Palsy C97150 NICHD Neurological Development Terminology A C97169 Athetoid Cerebral Palsy Athetoid Cerebral Palsy A subtype of cerebral palsy characterized by involuntary, purposeless writhing movements which affect the hands, feet, arms, and legs; the face and tongue may be affected as well, leading to involuntary grimacing, drooling, dysarthria and difficulty eating. C34460 Cerebral Palsy C97150 NICHD Neurological Development Terminology A C97170 Central Auditory Processing Disorder Central Auditory Processing Disorder A disorder characterized by impairment of the auditory processing, resulting in deficiencies in the recognition and interpretation of sounds by the brain. Causes include brain maturation delays and brain traumas or tumors. C97155 Language Disorder C97150 NICHD Neurological Development Terminology A C97171 Congenital Gastrointestinal Disorder Congenital Abnormality of the Digestive System An abnormality of the digestive system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C97150 NICHD Neurological Development Terminology A C97172 Congenital Nervous System Disorder Congenital Abnormality of the Nervous System An abnormality of the nervous system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C97150 NICHD Neurological Development Terminology A C97173 Congenital Respiratory System Disorder Congenital Abnormality of the Respiratory System An abnormality of the respiratory system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C97150 NICHD Neurological Development Terminology A C97174 Congenital Skin Disorder Congenital Abnormality of the Skin A skin abnormality that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C97150 NICHD Neurological Development Terminology A C97175 Low Vision Low Vision Reduced ability to perceive visual stimuli. C35126 Vision Disorder C97150 NICHD Neurological Development Terminology A C97176 Maternal Obesity Maternal Obesity Obesity in a female who has a child. C26836 Nutritional Disorder C97150 NICHD Neurological Development Terminology A C97177 Mixed Cerebral Palsy Mixed Cerebral Palsy A subtype of cerebral palsy characterized by both the tight muscle tone of spastic cerebral palsy and the writhing, involuntary muscle movements of athetoid cerebral palsy. C34460 Cerebral Palsy C97150 NICHD Neurological Development Terminology A C97178 Mixed Hearing Loss Mixed Hearing Loss A combination of conductive and sensorineural losses. C35731 Hearing Loss C97150 NICHD Neurological Development Terminology A C97179 Pervasive Developmental Disorder Pervasive Developmental Disorder A category of developmental disorders characterized by impaired communication and socialization skills. The impairments are incongruent with the individual's developmental level or mental age. These disorders can be associated with general medical or genetic conditions. C96412 Brain Development Abnormality C89338 Neurodevelopmental Disorder C97150 NICHD Neurological Development Terminology A C97193 Panic Disorder without Agoraphobia Panic Disorder without Agoraphobia A disorder in which an individual experiences recurrent, unexpected panic attacks and persistent concern about having additional panic attacks. Agoraphobia is not a component of this disorder. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology A C97194 Panic Disorder with Agoraphobia Panic Disorder with Agoraphobia A disorder in which an individual experiences recurrent, unexpected panic attacks and persistent concern about having additional panic attacks. Agoraphobia is a component of this disorder. C2878 Anxiety Disorder C97150 NICHD Neurological Development Terminology A C97250 Intellectual Disability Intellectual Disabilities A broad category of disorders characterized by an impairment to the intelligence an individual possesses. These impairments can result from trauma, birth or disease and are not restricted to any particular age group. C96413 Brain Disorder C97150 NICHD Neurological Development Terminology C C12219 Anatomic Structure, System, or Substance Anatomic Structure or System A human biological structure, fluid or other substance; excludes single molecular entities. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C C12326 Undescended Testis Undescended Testis The failure of one or both testes of a male fetus to descend from the abdomen into the scrotum during the late part of pregnancy. If not surgically corrected in early childhood, males may be at increased risk for testicular cancer later in life. C35107 Congenital Abnormality of the Genitourinary System C89506 NICHD Newborn Screening Terminology C C12326 Undescended Testis Undescended Testis The failure of one or both testes of a male fetus to descend from the abdomen into the scrotum during the late part of pregnancy. If not surgically corrected in early childhood, males may be at increased risk for testicular cancer later in life. C35107 Congenital Abnormality of the Genitourinary System C90259 NICHD Pediatric Terminology C C15220 Diagnosis Diagnosis The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation. C70856 Observational Result C89506 NICHD Newborn Screening Terminology C C15220 Diagnosis Diagnosis The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation. C70856 Observational Result C90259 NICHD Pediatric Terminology C C15256 Hysterectomy Hysterectomy A surgical procedure to remove the uterine body (partial hysterectomy) or the uterine body and cervix (total hysterectomy). -- 2004 C15332 Gynecologic Surgical Procedure C90259 NICHD Pediatric Terminology C C15256 Hysterectomy Hysterectomy A surgical procedure to remove the uterine body (partial hysterectomy) or the uterine body and cervix (total hysterectomy). -- 2004 C15332 Gynecologic Surgical Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C15291 Oophorectomy Oophorectomy Partial or complete removal of one or both of the ovaries. C15332 Gynecologic Surgical Procedure C90259 NICHD Pediatric Terminology C C15291 Oophorectomy Oophorectomy Partial or complete removal of one or both of the ovaries. C15332 Gynecologic Surgical Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C15348 Vasectomy Vasectomy Surgical removal of part or all of the vas deferens. C92892 Surgical Contraception Method C90259 NICHD Pediatric Terminology C C15348 Vasectomy Vasectomy Surgical removal of part or all of the vas deferens. C92892 Surgical Contraception Method C92712 NICHD Pregnancy & Childbirth Terminology C C15384 Surgical Incision Surgical Incision An intentional cut made to an individual's body with the intent of performing a diagnostic or therapeutic intervention. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology C C15384 Surgical Incision Surgical Incision An intentional cut made to an individual's body with the intent of performing a diagnostic or therapeutic intervention. C25218 Intervention or Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C15709 Genetic Testing Genetic Testing The process of isolating and testing the DNA of an embryo or a person to detect the presence of genetic alterations or defects that may predispose to the future development of a disease or disorder. C25294 Laboratory Procedure C89506 NICHD Newborn Screening Terminology C C15709 Genetic Testing Genetic Testing The process of isolating and testing the DNA of an embryo or a person to detect the presence of genetic alterations or defects that may predispose to the future development of a disease or disorder. C25294 Laboratory Procedure C90259 NICHD Pediatric Terminology C C16465 Conception Conception Fertilization of an ovum by a spermatozoon resulting in formation of a viable zygote. C21173 Reproductive Process C90259 NICHD Pediatric Terminology C C16465 Conception Conception Fertilization of an ovum by a spermatozoon resulting in formation of a viable zygote. C21173 Reproductive Process C92712 NICHD Pregnancy & Childbirth Terminology C C16576 Female Female A person who belongs to the sex that normally produces ova. The term is used to indicate biological sex distinctions, or cultural gender role distinctions, or both. C28421 Sex C89506 NICHD Newborn Screening Terminology C C16576 Female Female A person who belongs to the sex that normally produces ova. The term is used to indicate biological sex distinctions, or cultural gender role distinctions, or both. C28421 Sex C90259 NICHD Pediatric Terminology C C16580 in vitro Fertilization In Vitro Fertilization Fertilization of an ovum outside of the body. C92930 Conception Method C90259 NICHD Pediatric Terminology C C16580 in vitro Fertilization In Vitro Fertilization Fertilization of an ovum outside of the body. C92930 Conception Method C92712 NICHD Pregnancy & Childbirth Terminology C C16847 Technique Technique A practiced and regimented skill or series of actions. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology C C17103 Risk Factor Risk Factor Any aspect of an individual's life, behavior, an environmental exposure, or an inborn or inherited characteristic that increases the likelihood of a disease, condition or injury. C20189 Property or Attribute C89506 NICHD Newborn Screening Terminology C C17103 Risk Factor Risk Factor Any aspect of an individual's life, behavior, an environmental exposure, or an inborn or inherited characteristic that increases the likelihood of a disease, condition or injury. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C C17230 Ultrasonography Ultrasound Imaging Ultrasound A technique in which high-frequency sound waves are bounced off internal organs and the echo pattern is converted into a 2 dimensional picture of the structures beneath the transducer. C18020 Diagnostic Procedure C16847 Technique C89506 NICHD Newborn Screening Terminology C C17230 Ultrasonography Ultrasound Imaging Ultrasound A technique in which high-frequency sound waves are bounced off internal organs and the echo pattern is converted into a 2 dimensional picture of the structures beneath the transducer. C18020 Diagnostic Procedure C16847 Technique C90259 NICHD Pediatric Terminology C C17230 Ultrasonography Ultrasound Imaging Ultrasound A technique in which high-frequency sound waves are bounced off internal organs and the echo pattern is converted into a 2 dimensional picture of the structures beneath the transducer. C18020 Diagnostic Procedure C16847 Technique C92712 NICHD Pregnancy & Childbirth Terminology C C17348 Papanicolaou Smear Procedure Pap Smear A sample of secretions and superficial cells of the body of uterus, cervix, and ovaries; examined with a microscope to detect any abnormal cells. C15843 Preventive Intervention C90259 NICHD Pediatric Terminology C C17348 Papanicolaou Smear Procedure Pap Smear A sample of secretions and superficial cells of the body of uterus, cervix, and ovaries; examined with a microscope to detect any abnormal cells. C15843 Preventive Intervention C92712 NICHD Pregnancy & Childbirth Terminology C C20197 Male Male A person who belongs to the sex that normally produces sperm. The term is used to indicate biological sex distinctions, cultural gender role distinctions, or both. C28421 Sex C89506 NICHD Newborn Screening Terminology C C20197 Male Male A person who belongs to the sex that normally produces sperm. The term is used to indicate biological sex distinctions, cultural gender role distinctions, or both. C28421 Sex C90259 NICHD Pediatric Terminology C C20989 Physical Examination Physical Examination A systemic evaluation of the body and it's functions using visual inspection, palpation, percussion and auscultation. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment. C18020 Diagnostic Procedure C89506 NICHD Newborn Screening Terminology C C20989 Physical Examination Physical Examination A systemic evaluation of the body and it's functions using visual inspection, palpation, percussion and auscultation. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment. C18020 Diagnostic Procedure C90259 NICHD Pediatric Terminology C C20993 Research or Clinical Assessment Tool Clinical Assessment Tool Any one of several evaluation/assessment tools used to ascertain a patient's condition or diagnosis. C25214 Evaluation Procedure C90259 NICHD Pediatric Terminology C C21514 Temporal Qualifier Temporal Qualifier Terms used to indicate units of time or other terms associated with time. C20189 Property or Attribute C89506 NICHD Newborn Screening Terminology C C21514 Temporal Qualifier Temporal Qualifier Terms used to indicate units of time or other terms associated with time. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C C25155 Birth Birth The event of being born. C92934 Labor and Delivery Process C90259 NICHD Pediatric Terminology C C25155 Birth Birth The event of being born. C92934 Labor and Delivery Process C92712 NICHD Pregnancy & Childbirth Terminology C C25178 Health Health Refers to a person's state of physical, mental and social well-being; usually it refers specifically to the state of being in good health, a state of complete physical, mental and social well-being, and does not consist only of the absence of disease or infirmity. In any organism health constitutes a form of homeostasis with inputs and outputs of energy and mass in approximate equilibrium allowing for growth and continued survival. In humans, a subjective feeling of well-being coming from somatic and cognitive perceptions is considered an essential component of health. C92722 Qualitative Concept C89506 NICHD Newborn Screening Terminology C C25178 Health Health Refers to a person's state of physical, mental and social well-being; usually it refers specifically to the state of being in good health, a state of complete physical, mental and social well-being, and does not consist only of the absence of disease or infirmity. In any organism health constitutes a form of homeostasis with inputs and outputs of energy and mass in approximate equilibrium allowing for growth and continued survival. In humans, a subjective feeling of well-being coming from somatic and cognitive perceptions is considered an essential component of health. C92722 Qualitative Concept C90259 NICHD Pediatric Terminology C C25180 Indicator Indicator An event, entity or condition that typically characterizes a prescribed environment or situation and determines or aids in determining whether certain stated circumstances exist or criteria are satisfied. C92722 Qualitative Concept C89506 NICHD Newborn Screening Terminology C C25180 Indicator Indicator An event, entity or condition that typically characterizes a prescribed environment or situation and determines or aids in determining whether certain stated circumstances exist or criteria are satisfied. C92722 Qualitative Concept C90259 NICHD Pediatric Terminology C C25190 Person Person A human being. C90259 NICHD Pediatric Terminology C89506 NICHD Newborn Screening Terminology C C25190 Person Person A human being. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C C25207 Time Time The continuum of experience in which events pass from the future through the present to the past. C20189 Property or Attribute C89506 NICHD Newborn Screening Terminology C C25207 Time Time The continuum of experience in which events pass from the future through the present to the past. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C C25596 Breast Feeding Breast Feeding The nursing of an infant at the mother's breast. C19988 Organismal Process C89506 NICHD Newborn Screening Terminology C C25596 Breast Feeding Breast Feeding The nursing of an infant at the mother's breast. C19988 Organismal Process C90259 NICHD Pediatric Terminology C C25598 Observation Observation Watching something and taking note of what happens. C18020 Diagnostic Procedure C89506 NICHD Newborn Screening Terminology C C25598 Observation Observation Watching something and taking note of what happens. C18020 Diagnostic Procedure C90259 NICHD Pediatric Terminology C C25737 Identification Identification The procedure of having an identity established. C92722 Qualitative Concept C89506 NICHD Newborn Screening Terminology C C25737 Identification Identification The procedure of having an identity established. C92722 Qualitative Concept C90259 NICHD Pediatric Terminology C C26720 Chorioamnionitis Chorioamnionitis Inflammation of the fetal sac membranes. C27020 Female Reproductive System Disorder C90259 NICHD Pediatric Terminology C C26720 Chorioamnionitis Chorioamnionitis Inflammation of the fetal sac membranes. C27020 Female Reproductive System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C26734 Congenital Hypothyroidism Congenital Hypothyroidism A deficiency of thyroid hormone present at birth. The etiology can be genetic or environmental, or a combination of both; treatment is based on severity and causality. C34816 Congenital Metabolic Disorder C89506 NICHD Newborn Screening Terminology C C26734 Congenital Hypothyroidism Congenital Hypothyroidism A deficiency of thyroid hormone present at birth. The etiology can be genetic or environmental, or a combination of both; treatment is based on severity and causality. C34816 Congenital Metabolic Disorder C90259 NICHD Pediatric Terminology C C26785 Goiter Goiter Enlargement of the thyroid gland usually caused by lack of iodine in the diet, hyperthyroidism, or thyroid nodules. Symptoms include difficulty in breathing and swallowing. C3009 Endocrine System Disorder C26836 Nutritional Disorder C89506 NICHD Newborn Screening Terminology C C26785 Goiter Goiter Enlargement of the thyroid gland usually caused by lack of iodine in the diet, hyperthyroidism, or thyroid nodules. Symptoms include difficulty in breathing and swallowing. C3009 Endocrine System Disorder C26836 Nutritional Disorder C90259 NICHD Pediatric Terminology C C26836 Nutritional Disorder Nutritional Disorder Any condition related to a disturbance between proper intake and utilization of nourishment. C9229 Systemic Disorder C90259 NICHD Pediatric Terminology C C27644 Deafness Deafness An inherited or acquired condition characterized by a partial or complete loss of hearing in one or both ears. The level of impairment varies from a mild but important loss of sensitivity to a total loss of hearing. C35731 Hearing Loss C89506 NICHD Newborn Screening Terminology C C27644 Deafness Deafness An inherited or acquired condition characterized by a partial or complete loss of hearing in one or both ears. The level of impairment varies from a mild but important loss of sensitivity to a total loss of hearing. C35731 Hearing Loss C90259 NICHD Pediatric Terminology C C28258 Condom Condom A contraceptive device consisting of a thin rubber or latex sheath worn over the penis during intercourse. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C C28258 Condom Condom A contraceptive device consisting of a thin rubber or latex sheath worn over the penis during intercourse. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C C28421 Sex Sex The assemblage of physical properties or qualities by which male is distinguished from female; the physical difference between male and female; the distinguishing peculiarity of male or female. C25447 Characteristic C89506 NICHD Newborn Screening Terminology C C28421 Sex Sex The assemblage of physical properties or qualities by which male is distinguished from female; the physical difference between male and female; the distinguishing peculiarity of male or female. C25447 Characteristic C90259 NICHD Pediatric Terminology C C2849 Congenital Abnormality Congenital Abnormality Any abnormality, anatomical or biochemical, evident at birth or during the neonatal period. C89328 Pediatric Disease or Disorder C89506 NICHD Newborn Screening Terminology C C2849 Congenital Abnormality Congenital Abnormality Any abnormality, anatomical or biochemical, evident at birth or during the neonatal period. C89328 Pediatric Disease or Disorder C90259 NICHD Pediatric Terminology C C2893 Psychiatric Disorder Psychiatric Disorder A disorder characterized by behavioral and/or psychological abnormalities, often accompanied by physical symptoms. The symptoms may cause clinically significant distress or impairment in social and occupational areas of functioning. Representative examples include anxiety disorders, cognitive disorders, mood disorders and schizophrenia. C96413 Brain Disorder C90259 NICHD Pediatric Terminology C C2982 Depression Depression A melancholy feeling of sadness and despair. C2893 Psychiatric Disorder C90259 NICHD Pediatric Terminology C C2982 Depression Depression A melancholy feeling of sadness and despair. C2893 Psychiatric Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C3014 Endometriosis Endometriosis The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs. C27020 Female Reproductive System Disorder C90259 NICHD Pediatric Terminology C C3014 Endometriosis Endometriosis The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs. C27020 Female Reproductive System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C3085 Hemangioma Hemangioma A benign localized vascular neoplasm usually occurring in infancy and childhood. It is characterized by the formation of capillary-sized or cavernous vascular channels. The majority of cases are congenital. C2978 Cyst C89506 NICHD Newborn Screening Terminology C C3085 Hemangioma Hemangioma A benign localized vascular neoplasm usually occurring in infancy and childhood. It is characterized by the formation of capillary-sized or cavernous vascular channels. The majority of cases are congenital. C2978 Cyst C90259 NICHD Pediatric Terminology C C3101 Genetic Disorder Genetic Disorder Genetic Diseases are diseases in which inherited genes predispose to increased risk. The genetic disorders associated with cancer often result from an alteration or mutation in a single gene. The diseases range from rare dominant cancer family syndrome to familial tendencies in which low-penetrance genes may interact with other genes or environmental factors to induce cancer. Research may involve clinical, epidemiologic, and laboratory studies of persons, families, and populations at high risk of these disorders. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C C32221 Body Part Body Part Any part of an organism. C12219 Anatomic Structure or System C89506 NICHD Newborn Screening Terminology C C32221 Body Part Body Part Any part of an organism. C12219 Anatomic Structure or System C90259 NICHD Pediatric Terminology C C3231 Menopause Menopause The permanent cessation of menses, usually defined by 6 to 12 months of amenorrhea in a woman over 45 years of age. C19988 Organismal Process C90259 NICHD Pediatric Terminology C C3231 Menopause Menopause The permanent cessation of menses, usually defined by 6 to 12 months of amenorrhea in a woman over 45 years of age. C19988 Organismal Process C92712 NICHD Pregnancy & Childbirth Terminology C C3367 Finding Finding Objective evidence of disease perceptible to the examining physician (sign) and subjective evidence of disease perceived by the patient (symptom). C90259 NICHD Pediatric Terminology C89506 NICHD Newborn Screening Terminology C C3367 Finding Finding Objective evidence of disease perceptible to the examining physician (sign) and subjective evidence of disease perceived by the patient (symptom). C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C C3376 Sleep Disorder Sleep Disorder A change from the patient's baseline sleeping pattern, either an increase or a decrease in the number of hours slept. This can also refer to alterations in the stages of sleep. C9229 Systemic Disorder C90259 NICHD Pediatric Terminology C C34144 Embryologic Structure or System Embryonic Structure or System Body tissue, region, surface, cavity, fluid, organ, or collection of organs present in, or associated with, an embryo. C12219 Anatomic Structure or System C89506 NICHD Newborn Screening Terminology C C34144 Embryologic Structure or System Embryonic Structure or System Body tissue, region, surface, cavity, fluid, organ, or collection of organs present in, or associated with, an embryo. C12219 Anatomic Structure or System C90259 NICHD Pediatric Terminology C C34144 Embryologic Structure or System Embryonic Structure or System Body tissue, region, surface, cavity, fluid, organ, or collection of organs present in, or associated with, an embryo. C12219 Anatomic Structure or System C92712 NICHD Pregnancy & Childbirth Terminology C C3418 Toxoplasmosis Toxoplasmosis A parasitic disease contracted by the ingestion or fetal transmission of toxoplasma gondii. C27864 Parasitic Disease C90259 NICHD Pediatric Terminology C C3418 Toxoplasmosis Toxoplasmosis A parasitic disease contracted by the ingestion or fetal transmission of toxoplasma gondii. C27864 Parasitic Disease C92712 NICHD Pregnancy & Childbirth Terminology C C34376 Hemolytic Anemia Hemolytic Anemia Anemia resulting from the premature destruction of the peripheral blood red cells. It may be congenital or it may be caused by infections, medications, or malignancies. C26323 Hematological Disorder C90259 NICHD Pediatric Terminology C C34376 Hemolytic Anemia Hemolytic Anemia Anemia resulting from the premature destruction of the peripheral blood red cells. It may be congenital or it may be caused by infections, medications, or malignancies. C26323 Hematological Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C34383 Sickle Cell Disease Sickle Cell Disease A blood disorder characterized by the appearance of sickle-shaped red blood cells and anemia. C35729 Congenital Abnormality of the Circulatory System C89506 NICHD Newborn Screening Terminology C C34383 Sickle Cell Disease Sickle Cell Disease A blood disorder characterized by the appearance of sickle-shaped red blood cells and anemia. C35729 Congenital Abnormality of the Circulatory System C90259 NICHD Pediatric Terminology C C34491 Clubbing of Fingers Clubbing of Fingers An abnormal enlargement of the terminal phalanges accompanied by increased length-wise curvature of the nails, giving the digits a club-like appearance. Clubbing has been noted with a wide variety of conditions, including pulmonary and cardiac diseases, liver disorders, and disorders of the gastrointestinal tract. C89337 Congenital Abnormality of the Musculoskeletal System C89506 NICHD Newborn Screening Terminology C C34491 Clubbing of Fingers Clubbing of Fingers An abnormal enlargement of the terminal phalanges accompanied by increased length-wise curvature of the nails, giving the digits a club-like appearance. Clubbing has been noted with a wide variety of conditions, including pulmonary and cardiac diseases, liver disorders, and disorders of the gastrointestinal tract. C89337 Congenital Abnormality of the Musculoskeletal System C90259 NICHD Pediatric Terminology C C34675 Hemoglobin C Disease Hemoglobin C Disease A blood disorder characterized by the appearance of sickle-shaped red blood cells and anemia. This disorder is caused by a specific mutation in the beta-globin HBB gene, whereby a lysine is substituted for a glutamic acid at the sixth amino acid in the protein. C35729 Congenital Abnormality of the Circulatory System C89506 NICHD Newborn Screening Terminology C C34675 Hemoglobin C Disease Hemoglobin C Disease A blood disorder characterized by the appearance of sickle-shaped red blood cells and anemia. This disorder is caused by a specific mutation in the beta-globin HBB gene, whereby a lysine is substituted for a glutamic acid at the sixth amino acid in the protein. C35729 Congenital Abnormality of the Circulatory System C90259 NICHD Pediatric Terminology C C34687 Diaphragmatic Hernia Diaphragmatic Hernia A congenital or acquired weakness or opening in the diaphragm which allows abdominal contents to protrude into the chest cavity; congenital diaphragmatic hernias are caused when the embryonic diaphragm fails to fuse. C89337 Congenital Abnormality of the Musculoskeletal System C89506 NICHD Newborn Screening Terminology C C34687 Diaphragmatic Hernia Diaphragmatic Hernia A congenital or acquired weakness or opening in the diaphragm which allows abdominal contents to protrude into the chest cavity; congenital diaphragmatic hernias are caused when the embryonic diaphragm fails to fuse. C89337 Congenital Abnormality of the Musculoskeletal System C90259 NICHD Pediatric Terminology C C34724 Low Birth Weight Low Birth Weight Refers to a fetus or infant who is smaller than expected for the age or gender, or who has a birthweight less than the 10th percentile. C76325 Birth Weight C89506 NICHD Newborn Screening Terminology C C34724 Low Birth Weight Low Birth Weight Refers to a fetus or infant who is smaller than expected for the age or gender, or who has a birthweight less than the 10th percentile. C76325 Birth Weight C90259 NICHD Pediatric Terminology C C34724 Low Birth Weight Low Birth Weight Refers to a fetus or infant who is smaller than expected for the age or gender, or who has a birthweight less than the 10th percentile. C76325 Birth Weight C92712 NICHD Pregnancy & Childbirth Terminology C C34781 Spastic Diplegia Spastic Diplegia A type of cerebral palsy characterized by spasticity and hypertonia of the lower extremities bilaterally, particularly the legs, hips, and pelvis; this is the most common (70%) form of cerebral palsy. C34460 Cerebral Palsy C89506 NICHD Newborn Screening Terminology C C34781 Spastic Diplegia Spastic Diplegia A type of cerebral palsy characterized by spasticity and hypertonia of the lower extremities bilaterally, particularly the legs, hips, and pelvis; this is the most common (70%) form of cerebral palsy. C34460 Cerebral Palsy C90259 NICHD Pediatric Terminology C C34816 Congenital Metabolic Disorder Congenital Metabolic Disorder A group of disorders present at birth that involve genetic defects leading to disturbances in carbohydrate, lipid, lysosomal storage or amino acid metabolism in the body. C97151 Systemic Congenital Disorder C89506 NICHD Newborn Screening Terminology C C34816 Congenital Metabolic Disorder Congenital Metabolic Disorder A group of disorders present at birth that involve genetic defects leading to disturbances in carbohydrate, lipid, lysosomal storage or amino acid metabolism in the body. C97151 Systemic Congenital Disorder C90259 NICHD Pediatric Terminology C C34941 Pregnancy Complication Pregnancy Complication The co-occurrence of pregnancy and a disease. The disease may precede or follow conception and it may or may not have a deleterious effect on the pregnant woman or fetus. C2991 Disease or Disorder C89506 NICHD Newborn Screening Terminology C C34941 Pregnancy Complication Pregnancy Complication The co-occurrence of pregnancy and a disease. The disease may precede or follow conception and it may or may not have a deleterious effect on the pregnant woman or fetus. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C C34965 Pyelonephritis Pyelonephritis An acute or chronic inflammatory process affecting the kidney. It is caused by bacteria and in most cases it is the result of a urinary tract infection. Signs and symptoms include fever, chills, flank pain, painful and frequent urination, cloudy or bloody urine, and confusion. C2890 Bacterial Disease C90259 NICHD Pediatric Terminology C C34965 Pyelonephritis Pyelonephritis An acute or chronic inflammatory process affecting the kidney. It is caused by bacteria and in most cases it is the result of a urinary tract infection. Signs and symptoms include fever, chills, flank pain, painful and frequent urination, cloudy or bloody urine, and confusion. C2890 Bacterial Disease C92712 NICHD Pregnancy & Childbirth Terminology C C35024 Sinusitis Sinus Infection An acute or chronic infectious process affecting the mucous membranes of the paranasal sinuses. C26726 Infectious Disease C26871 Respiratory System Disorder C90259 NICHD Pediatric Terminology C C35024 Sinusitis Sinus Infection An acute or chronic infectious process affecting the mucous membranes of the paranasal sinuses. C26726 Infectious Disease C26871 Respiratory System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C35040 Strabismus Strabismus Strabismus is the intermittent or constant misalignment of an eye so that its line of vision is not pointed at the same object as the other eye. Strabismus is caused by an imbalance in the extraocular muscles which control the positioning of the eyes. Strabismus is normal in newborns but should resolve by the time the baby is 6 months old. In older children with strabismus, the brain may learn to ignore the input from one eye, and this may lead to amblyopia, a potentially permanent decrease in vision in that eye if not corrected. C35126 Vision Disorder C89506 NICHD Newborn Screening Terminology C C35040 Strabismus Strabismus Strabismus is the intermittent or constant misalignment of an eye so that its line of vision is not pointed at the same object as the other eye. Strabismus is caused by an imbalance in the extraocular muscles which control the positioning of the eyes. Strabismus is normal in newborns but should resolve by the time the baby is 6 months old. In older children with strabismus, the brain may learn to ignore the input from one eye, and this may lead to amblyopia, a potentially permanent decrease in vision in that eye if not corrected. C35126 Vision Disorder C90259 NICHD Pediatric Terminology C C36284 Reproductive System Finding Reproductive System Finding Symptoms, physical examination results, and/or laboratory test results related to the reproductive system. C70856 Observational Result C90259 NICHD Pediatric Terminology C C36284 Reproductive System Finding Reproductive System Finding Symptoms, physical examination results, and/or laboratory test results related to the reproductive system. C70856 Observational Result C92712 NICHD Pregnancy & Childbirth Terminology C C3724 Cystic Hygroma Cystic Hygroma Cystic Lymphangioma A benign lymphatic neoplasm usually arising from the neck and characterized by cystic dilation of the lymphatic vessels. C2978 Cyst C89506 NICHD Newborn Screening Terminology C C3724 Cystic Hygroma Cystic Hygroma Cystic Lymphangioma A benign lymphatic neoplasm usually arising from the neck and characterized by cystic dilation of the lymphatic vessels. C2978 Cyst C90259 NICHD Pediatric Terminology C C38013 Range Range The difference between the lowest and highest numerical values; the limits or scale of variation. C70766 Quantitative Concept C89506 NICHD Newborn Screening Terminology C C38013 Range Range The difference between the lowest and highest numerical values; the limits or scale of variation. C70766 Quantitative Concept C90259 NICHD Pediatric Terminology C C38036 Audiometric Test Audiometric Test Testing conducted utilizing a manual or microprocessor audiometer to test for hearing loss. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C38036 Audiometric Test Audiometric Test Testing conducted utilizing a manual or microprocessor audiometer to test for hearing loss. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C3836 Infertility Infertility Inability to conceive for at least one year after trying and having unprotected sex. Causes of female infertility include endometriosis, fallopian tubes obstruction, and polycystic ovary syndrome. Causes of male infertility include abnormal sperm production or function, blockage of the epididymis, blockage of the ejaculatory ducts, hypospadias, exposure to pesticides, and health related issues. C27020 Female Reproductive System Disorder C90259 NICHD Pediatric Terminology C C3836 Infertility Infertility Inability to conceive for at least one year after trying and having unprotected sex. Causes of female infertility include endometriosis, fallopian tubes obstruction, and polycystic ovary syndrome. Causes of male infertility include abnormal sperm production or function, blockage of the epididymis, blockage of the ejaculatory ducts, hypospadias, exposure to pesticides, and health related issues. C27020 Female Reproductive System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C389 Oral Contraceptive Oral Contraceptive Pill An agent taken orally to prevent conception. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C C389 Oral Contraceptive Oral Contraceptive Pill An agent taken orally to prevent conception. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C C3890 Hypoxia Hypoxia A decrease in the amount of oxygen in the body. Symptoms range from mild (impaired judgment, memory loss, impaired motor coordination) to severe (seizures and coma). C81236 Birth Complication C89506 NICHD Newborn Screening Terminology C C3890 Hypoxia Hypoxia A decrease in the amount of oxygen in the body. Symptoms range from mild (impaired judgment, memory loss, impaired motor coordination) to severe (seizures and coma). C81236 Birth Complication C90259 NICHD Pediatric Terminology C C41148 Placement Placement Position or arrangement, as of the teeth; the state of being placed or arranged, as the assignment of a person to a appropriate clinical study. C92722 Qualitative Concept C89506 NICHD Newborn Screening Terminology C C41148 Placement Placement Position or arrangement, as of the teeth; the state of being placed or arranged, as the assignment of a person to a appropriate clinical study. C92722 Qualitative Concept C90259 NICHD Pediatric Terminology C C42767 Vaginal Diaphragm Vaginal Diaphragm A medical contraceptive device of soft flexible material, usually of thin rubber, that is designed to cover the cervix uteri prior to sexual intercourse to prevent the entry of spermatozoa. To enhance efficacy, a spermicidal agent is often placed within the device. Antimicrobial agent(s) can also be used to prevent sexually transmitted diseases. Efficacy of vaginal diaphragm against infections is very limited. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C C42767 Vaginal Diaphragm Vaginal Diaphragm A medical contraceptive device of soft flexible material, usually of thin rubber, that is designed to cover the cervix uteri prior to sexual intercourse to prevent the entry of spermatozoa. To enhance efficacy, a spermicidal agent is often placed within the device. Antimicrobial agent(s) can also be used to prevent sexually transmitted diseases. Efficacy of vaginal diaphragm against infections is very limited. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C C42771 Intrauterine Device Intra Uterine Device A device usually made of plastic or metal, inserted into the uterus to prevent conception. IUCD can be a coil, loop, triangle, or T in shape; its material can be impregnated with a pharmaceutical agent. The primary action of all IUCDs is the induction of a foreign-body reaction within the endometrium. This sterile inflammatory process is toxic to gametes, primarily spermatozoa, and effectively prevents viable sperm from passing into the fallopian tubes. The copper-bearing device has an independent toxic effect on spermatozoa. The progestin-releasing devices produce changes in endometrial architecture and function that reduce the potential for implantation of a fertilized egg. The progestin effect on the cervical mucus also reduces the penetrability of sperm. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C C42771 Intrauterine Device Intra Uterine Device A device usually made of plastic or metal, inserted into the uterus to prevent conception. IUCD can be a coil, loop, triangle, or T in shape; its material can be impregnated with a pharmaceutical agent. The primary action of all IUCDs is the induction of a foreign-body reaction within the endometrium. This sterile inflammatory process is toxic to gametes, primarily spermatozoa, and effectively prevents viable sperm from passing into the fallopian tubes. The copper-bearing device has an independent toxic effect on spermatozoa. The progestin-releasing devices produce changes in endometrial architecture and function that reduce the potential for implantation of a fertilized egg. The progestin effect on the cervical mucus also reduces the penetrability of sperm. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C C45306 Substance Substance A material with particular features. C90259 NICHD Pediatric Terminology C90259 NICHD Pediatric Terminology C C47868 Blood Chemistry Measurement Blood Test The determination of the measured concentrations of chemical constituents of the blood by assay in a clinical laboratory. C18020 Diagnostic Procedure C90259 NICHD Pediatric Terminology C C47868 Blood Chemistry Measurement Blood Test The determination of the measured concentrations of chemical constituents of the blood by assay in a clinical laboratory. C18020 Diagnostic Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C49100 Data Value Data Value The information contained in a data field. It may represent a numeric quantity, a textual characterization, a date or time measurement, or some other state, depending on the nature of the attribute. C20189 Property or Attribute C89506 NICHD Newborn Screening Terminology C C49100 Data Value Data Value The information contained in a data field. It may represent a numeric quantity, a textual characterization, a date or time measurement, or some other state, depending on the nature of the attribute. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C C49672 Vital Signs Vital Sign Measurement A character or string that represents the vital signs examination. C18020 Diagnostic Procedure C89506 NICHD Newborn Screening Terminology C C49672 Vital Signs Vital Sign Measurement A character or string that represents the vital signs examination. C18020 Diagnostic Procedure C90259 NICHD Pediatric Terminology C C49676 Pulse Rate Pulse Rate The rate of the pulse as observed in an artery, expressed as beats per minute. It can be measured at several anatomical sites, including the wrist, neck, temple, groin, behind the knees, or on top of the foot. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C C49676 Pulse Rate Pulse Rate The rate of the pulse as observed in an artery, expressed as beats per minute. It can be measured at several anatomical sites, including the wrist, neck, temple, groin, behind the knees, or on top of the foot. C81274 Numeric Value C90259 NICHD Pediatric Terminology C C49677 Heart Rate Heart Rate The number of heartbeats per unit of time, usually expressed as beats per minute. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C C49677 Heart Rate Heart Rate The number of heartbeats per unit of time, usually expressed as beats per minute. C81274 Numeric Value C90259 NICHD Pediatric Terminology C C49678 Respiratory Rate Respiratory Rate The rate of breathing (inhalation and exhalation) measured within in a unit time, usually expressed as breaths per minute. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C C49678 Respiratory Rate Respiratory Rate The rate of breathing (inhalation and exhalation) measured within in a unit time, usually expressed as breaths per minute. C81274 Numeric Value C90259 NICHD Pediatric Terminology C C50583 Herpes Herpes Any inflammatory skin disease caused by a herpesvirus and characterized by the formation of small vesicles in clusters. C3439 Viral Disease C90259 NICHD Pediatric Terminology C C50583 Herpes Herpes Any inflammatory skin disease caused by a herpesvirus and characterized by the formation of small vesicles in clusters. C3439 Viral Disease C92712 NICHD Pregnancy & Childbirth Terminology C C50791 Urinary Tract Infection Urinary Tract Infection A bacterial infectious process affecting any part of the urinary tract, most commonly the bladder and the urethra. Symptoms include urinary urgency and frequency, burning sensation during urination, lower abdominal discomfort, and cloudy urine. C3430 Urinary System Disorder C90259 NICHD Pediatric Terminology C C50791 Urinary Tract Infection Urinary Tract Infection A bacterial infectious process affecting any part of the urinary tract, most commonly the bladder and the urethra. Symptoms include urinary urgency and frequency, burning sensation during urination, lower abdominal discomfort, and cloudy urine. C3430 Urinary System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C54706 Blood Pressure Blood Pressure The pressure of the circulating blood against the walls of the blood vessels. C25447 Characteristic C89506 NICHD Newborn Screening Terminology C C54706 Blood Pressure Blood Pressure The pressure of the circulating blood against the walls of the blood vessels. C25447 Characteristic C90259 NICHD Pediatric Terminology C C54706 Blood Pressure Blood Pressure The pressure of the circulating blood against the walls of the blood vessels. C25447 Characteristic C92712 NICHD Pregnancy & Childbirth Terminology C C61009 Blood Type Blood Type The specific reaction pattern of erythrocytes of an individual to the antisera of one blood group; e.g., the ABO blood group consists of four major blood types: O, A, B, and AB. This classification depends on the presence or absence of two major antigens: A or B. Type O occurs when neither is present and type AB when both are present. The blood type is the genetic phenotype of the individual for one blood group system and may be determined using different antisera available for testing. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C C61009 Blood Type Blood Type The specific reaction pattern of erythrocytes of an individual to the antisera of one blood group; e.g., the ABO blood group consists of four major blood types: O, A, B, and AB. This classification depends on the presence or absence of two major antigens: A or B. Type O occurs when neither is present and type AB when both are present. The blood type is the genetic phenotype of the individual for one blood group system and may be determined using different antisera available for testing. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C62736 Cognitive Assessment Cognitive Assessment The examination of the cognitive capacities or deficits of an individual through the application of tests that probe that individual's ability to perform various mental activities such as perception, learning, and reasoning. C81313 Neurologic Examination C89506 NICHD Newborn Screening Terminology C C62736 Cognitive Assessment Cognitive Assessment The examination of the cognitive capacities or deficits of an individual through the application of tests that probe that individual's ability to perform various mental activities such as perception, learning, and reasoning. C81313 Neurologic Examination C90259 NICHD Pediatric Terminology C C64848 Hemoglobin Measurement Hemoglobin Measurement A quantitative measurement of the amount of hemoglobin present in a sample. C25294 Laboratory Procedure C89506 NICHD Newborn Screening Terminology C C64848 Hemoglobin Measurement Hemoglobin Measurement A quantitative measurement of the amount of hemoglobin present in a sample. C25294 Laboratory Procedure C90259 NICHD Pediatric Terminology C C64848 Hemoglobin Measurement Hemoglobin Measurement A quantitative measurement of the amount of hemoglobin present in a sample. C25294 Laboratory Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C66849 Ovulation Ovulation Release of Egg The discharge of a secondary oocyte from a vesicular follicle of the ovary. C21173 Reproductive Process C90259 NICHD Pediatric Terminology C C66849 Ovulation Ovulation Release of Egg The discharge of a secondary oocyte from a vesicular follicle of the ovary. C21173 Reproductive Process C92712 NICHD Pregnancy & Childbirth Terminology C C69055 Contraceptive Sponge Contraceptive Sponge A sponge impregnated with an antispermicidal agent; it is designed to be placed into the vaginal canal to prevent live sperm from entering the uterus. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C C69055 Contraceptive Sponge Contraceptive Sponge A sponge impregnated with an antispermicidal agent; it is designed to be placed into the vaginal canal to prevent live sperm from entering the uterus. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C C70766 Quantitative Quantitative Concept Capable of being estimated or expressed with numeric values. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C C70766 Quantitative Quantitative Concept Capable of being estimated or expressed with numeric values. C20189 Property or Attribute C92712 NICHD Pregnancy & Childbirth Terminology C C73437 APGAR Score APGAR Score The numerical sum between zero and ten that is computed from individual values of zero to two that are assigned to five different areas of interest in newborn screenings. These areas are breathing, muscle tone, pulse rate, reflex irritability and skin color. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C C73437 APGAR Score APGAR Score The numerical sum between zero and ten that is computed from individual values of zero to two that are assigned to five different areas of interest in newborn screenings. These areas are breathing, muscle tone, pulse rate, reflex irritability and skin color. C81274 Numeric Value C90259 NICHD Pediatric Terminology C C75387 Human Chorionic Gonadotropin Measurement Human Chorionic Gonadotropin Measurement A laboratory test to detect the amount of human chorionic gonadotropin in a biospecimen. C92949 Pregnancy Test C90259 NICHD Pediatric Terminology C C75387 Human Chorionic Gonadotropin Measurement Human Chorionic Gonadotropin Measurement A laboratory test to detect the amount of human chorionic gonadotropin in a biospecimen. C92949 Pregnancy Test C92712 NICHD Pregnancy & Childbirth Terminology C C76325 Birth Weight Birth Weight In humans, the weight of a neonate measured within one hour after birth. The factors influencing the birth weight include but not limited to infant sex, racial and ethnic group, maternal size and health status, concurrent diseases, parity, and nutrition, pregnancy environment and conditions, e.g. altitude of geographic area. C81328 Body Weight C89506 NICHD Newborn Screening Terminology C C76325 Birth Weight Birth Weight In humans, the weight of a neonate measured within one hour after birth. The factors influencing the birth weight include but not limited to infant sex, racial and ethnic group, maternal size and health status, concurrent diseases, parity, and nutrition, pregnancy environment and conditions, e.g. altitude of geographic area. C81328 Body Weight C90259 NICHD Pediatric Terminology C C77140 Clinical Test Result Clinical Test Result The result of a laboratory, radiologic, or other clinical test performed to determine the presence, absence, or degree of a condition. C70856 Observational Result C89506 NICHD Newborn Screening Terminology C C77140 Clinical Test Result Clinical Test Result The result of a laboratory, radiologic, or other clinical test performed to determine the presence, absence, or degree of a condition. C70856 Observational Result C90259 NICHD Pediatric Terminology C C78293 Fallopian Tube Obstruction Fallopian Tube Obstruction Blockage of the normal flow of the contents in the fallopian tube. C27020 Female Reproductive System Disorder C90259 NICHD Pediatric Terminology C C78293 Fallopian Tube Obstruction Fallopian Tube Obstruction Blockage of the normal flow of the contents in the fallopian tube. C27020 Female Reproductive System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C78603 Scoliosis Scoliosis A congenital or acquired spine deformity characterized by lateral curvature of the spine. C27574 Musculoskeletal System Disorder C90259 NICHD Pediatric Terminology C C78742 Lochia Lochial Flow Vaginal discharge occurring during the post-partum period. It consists of a mixture of blood, mucus, and placental remnants. C92935 Postpartum Process C90259 NICHD Pediatric Terminology C C78742 Lochia Lochial Flow Vaginal discharge occurring during the post-partum period. It consists of a mixture of blood, mucus, and placental remnants. C92935 Postpartum Process C92712 NICHD Pregnancy & Childbirth Terminology C C81178 Newborn Screening Newborn Screening A specific type of newborn examination performed to allow for early detection of disease(s) and/or disorder(s). C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C81178 Newborn Screening Newborn Screening A specific type of newborn examination performed to allow for early detection of disease(s) and/or disorder(s). C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C81181 Infant Reflex Infant Reflex Primitive reflex actions that newborns display in response to specific stimuli. These reflexes are involuntary and most disappear as the infant matures. C90346 Child Behavior C89506 NICHD Newborn Screening Terminology C C81181 Infant Reflex Infant Reflex Primitive reflex actions that newborns display in response to specific stimuli. These reflexes are involuntary and most disappear as the infant matures. C90346 Child Behavior C90259 NICHD Pediatric Terminology C C81184 Vernier Caliper Vernier Caliper A medical device that is a combination of ruler and caliper that can measure the distance between two points. The configuration of this device permits the measurement of internal dimensions. C81182 Measurement Device C89506 NICHD Newborn Screening Terminology C C81184 Vernier Caliper Vernier Caliper A medical device that is a combination of ruler and caliper that can measure the distance between two points. The configuration of this device permits the measurement of internal dimensions. C81182 Measurement Device C90259 NICHD Pediatric Terminology C C81230 APGAR Test APGAR Test A test devised by Dr. Virginia Apgar to assess the overall health of a newborn upon birth. The test is administered at one and five minutes after birth and allows for the assignation of numerical values between zero and two for specific observations regarding skin color, pulse rate, reflex irritability, muscle tone and breathing. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C81230 APGAR Test APGAR Test A test devised by Dr. Virginia Apgar to assess the overall health of a newborn upon birth. The test is administered at one and five minutes after birth and allows for the assignation of numerical values between zero and two for specific observations regarding skin color, pulse rate, reflex irritability, muscle tone and breathing. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C81232 Bayley Scales of Infant Development Bayley Scales of Infant Development A standardized series of measurements that assesses the cognitive, motor, and behavioral development in infants and babies from one to twenty-four months of age. C81314 Newborn Behavioral Examination C89506 NICHD Newborn Screening Terminology C C81232 Bayley Scales of Infant Development Bayley Scales of Infant Development A standardized series of measurements that assesses the cognitive, motor, and behavioral development in infants and babies from one to twenty-four months of age. C81314 Newborn Behavioral Examination C90259 NICHD Pediatric Terminology C C81234 Behavioral Assessment Behavioral Assessment Assessment of individual responses to age appropriate stimuli. C25214 Evaluation Procedure C89506 NICHD Newborn Screening Terminology C C81234 Behavioral Assessment Behavioral Assessment Assessment of individual responses to age appropriate stimuli. C25214 Evaluation Procedure C90259 NICHD Pediatric Terminology C C81235 Behavioral Rating Scale Behavioral Rating Scale A range of values designed to quantify the qualitative responses of an individual to a set of challenges. C81314 Newborn Behavioral Examination C89506 NICHD Newborn Screening Terminology C C81235 Behavioral Rating Scale Behavioral Rating Scale A range of values designed to quantify the qualitative responses of an individual to a set of challenges. C81314 Newborn Behavioral Examination C90259 NICHD Pediatric Terminology C C81236 Birth Complication Birth Complication The development of a problematic medical situation that occurs concurrently with the birth of a neonate. C92718 Finding during Childbirth Labor C89506 NICHD Newborn Screening Terminology C C81236 Birth Complication Birth Complication The development of a problematic medical situation that occurs concurrently with the birth of a neonate. C92718 Finding during Childbirth Labor C90259 NICHD Pediatric Terminology C C81236 Birth Complication Birth Complication The development of a problematic medical situation that occurs concurrently with the birth of a neonate. C92718 Finding during Childbirth Labor C92712 NICHD Pregnancy & Childbirth Terminology C C81238 Brazelton Neonatal Behavioral Assessment Scale Brazelton Neonatal Behavioral Assessment Scale An assessment tool created by Dr. T. Berry Brazelton and his colleagues to assist caregivers in determining developmental strengths and weaknesses in infants from birth to the age of two months. C81314 Newborn Behavioral Examination C89506 NICHD Newborn Screening Terminology C C81238 Brazelton Neonatal Behavioral Assessment Scale Brazelton Neonatal Behavioral Assessment Scale An assessment tool created by Dr. T. Berry Brazelton and his colleagues to assist caregivers in determining developmental strengths and weaknesses in infants from birth to the age of two months. C81314 Newborn Behavioral Examination C90259 NICHD Pediatric Terminology C C81239 Cause of Death Cause of Death The circumstance or condition that results in the death of a living being. C70856 Observational Result C89506 NICHD Newborn Screening Terminology C C81239 Cause of Death Cause of Death The circumstance or condition that results in the death of a living being. C70856 Observational Result C90259 NICHD Pediatric Terminology C C81240 Cellular Telephone Number Cellular Telephone Number The sequence of numbers or characters, that when dialed, connects to a particular cellular telephone. C40978 Telephone Number C89506 NICHD Newborn Screening Terminology C C81240 Cellular Telephone Number Cellular Telephone Number The sequence of numbers or characters, that when dialed, connects to a particular cellular telephone. C40978 Telephone Number C90259 NICHD Pediatric Terminology C C81242 Crown to Rump Length Measurement Crown to Rump Length Measurement A measurement from the high prominence of the head to the low prominence of the buttocks of a fetus or embryo during ultrasound. This measurement is useful in determining gestational age. C81253 Gestational Weeks Assessment C89506 NICHD Newborn Screening Terminology C C81242 Crown to Rump Length Measurement Crown to Rump Length Measurement A measurement from the high prominence of the head to the low prominence of the buttocks of a fetus or embryo during ultrasound. This measurement is useful in determining gestational age. C81253 Gestational Weeks Assessment C90259 NICHD Pediatric Terminology C C81245 Denver Development Screening Test Denver Development Screening Test A test developed at the University of Colorado Medical Center to assess the developmental status of infants and children from birth to six years of age. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C81245 Denver Development Screening Test Denver Development Screening Test A test developed at the University of Colorado Medical Center to assess the developmental status of infants and children from birth to six years of age. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C81247 Expected Date of Confinement Expected Date of Confinement The projected date of delivery for a pregnant female. C25164 Date C89506 NICHD Newborn Screening Terminology C C81247 Expected Date of Confinement Expected Date of Confinement The projected date of delivery for a pregnant female. C25164 Date C90259 NICHD Pediatric Terminology C C81247 Expected Date of Confinement Expected Date of Confinement The projected date of delivery for a pregnant female. C25164 Date C92712 NICHD Pregnancy & Childbirth Terminology C C81248 Forceps Delivery Forceps Delivery The method referring to the delivery of a fetus through the vaginal canal with assistance of obstetrical forceps. C81301 Vaginal Assisted Delivery C89506 NICHD Newborn Screening Terminology C C81248 Forceps Delivery Forceps Delivery The method referring to the delivery of a fetus through the vaginal canal with assistance of obstetrical forceps. C81301 Vaginal Assisted Delivery C90259 NICHD Pediatric Terminology C C81248 Forceps Delivery Forceps Delivery The method referring to the delivery of a fetus through the vaginal canal with assistance of obstetrical forceps. C81301 Vaginal Assisted Delivery C92712 NICHD Pregnancy & Childbirth Terminology C C81252 Gesell Developmental Schedule Gesell Developmental Schedule A scale used as an instrument to assess a child's motor and language development, as well as personal-social and adaptive behaviors. C81314 Newborn Behavioral Examination C89506 NICHD Newborn Screening Terminology C C81252 Gesell Developmental Schedule Gesell Developmental Schedule A scale used as an instrument to assess a child's motor and language development, as well as personal-social and adaptive behaviors. C81314 Newborn Behavioral Examination C90259 NICHD Pediatric Terminology C C81253 Gestational Weeks Assessment Gestational Weeks Assessment A standard determination of fetal age; it is the number of weeks since the first day of the last menstrual period of the mother to the date of interest. C90341 Pediatric Intervention or Procedure C89506 NICHD Newborn Screening Terminology C C81253 Gestational Weeks Assessment Gestational Weeks Assessment A standard determination of fetal age; it is the number of weeks since the first day of the last menstrual period of the mother to the date of interest. C90341 Pediatric Intervention or Procedure C90259 NICHD Pediatric Terminology C C81255 Head Circumference Head Circumference A circumferential measurement of the head at the widest point, which is traditionally above the eyebrows. C25334 Length C89506 NICHD Newborn Screening Terminology C C81255 Head Circumference Head Circumference A circumferential measurement of the head at the widest point, which is traditionally above the eyebrows. C25334 Length C90259 NICHD Pediatric Terminology C C81261 Measuring Tape Measuring Tape A pliable length of fabric, plastic, paper or some composite that is has incremental lengths imprinted on the surface. C81182 Measurement Device C89506 NICHD Newborn Screening Terminology C C81261 Measuring Tape Measuring Tape A pliable length of fabric, plastic, paper or some composite that is has incremental lengths imprinted on the surface. C81182 Measurement Device C90259 NICHD Pediatric Terminology C C81263 Mental Development Index Mental Development Index A sequential arrangement of information pertaining to the evolution of an individual's cognitive development. C81314 Newborn Behavioral Examination C89506 NICHD Newborn Screening Terminology C C81263 Mental Development Index Mental Development Index A sequential arrangement of information pertaining to the evolution of an individual's cognitive development. C81314 Newborn Behavioral Examination C90259 NICHD Pediatric Terminology C C81264 Mental Scale Mental Scale A range of values that characterizes an individual's mental development. C81314 Newborn Behavioral Examination C89506 NICHD Newborn Screening Terminology C C81264 Mental Scale Mental Scale A range of values that characterizes an individual's mental development. C81314 Newborn Behavioral Examination C90259 NICHD Pediatric Terminology C C81267 Feeding Method Feeding Method A description of the technique for the manner in which a subject is administered food. C16847 Technique C89506 NICHD Newborn Screening Terminology C C81267 Feeding Method Feeding Method A description of the technique for the manner in which a subject is administered food. C16847 Technique C90259 NICHD Pediatric Terminology C C81270 Newborn Motor Scale Newborn Motor Scale A range of values used to quantify newborn motor development. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C C81270 Newborn Motor Scale Newborn Motor Scale A range of values used to quantify newborn motor development. C81274 Numeric Value C90259 NICHD Pediatric Terminology C C81272 First Feeding First Feeding The first time that a neonate is provided nutrition. C25207 Time C89506 NICHD Newborn Screening Terminology C C81272 First Feeding First Feeding The first time that a neonate is provided nutrition. C25207 Time C90259 NICHD Pediatric Terminology C C81282 Dubowitz Score Ballard/Dubowitz Score The numerical value that represents a clinical assessment of neurological and physical criteria, performed between birth and five days of age, to determine an infant's gestational age and maturity. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C C81282 Dubowitz Score Ballard/Dubowitz Score The numerical value that represents a clinical assessment of neurological and physical criteria, performed between birth and five days of age, to determine an infant's gestational age and maturity. C81274 Numeric Value C90259 NICHD Pediatric Terminology C C81283 Red Reflex Vision Test Red Reflex Vision Test An optic examination in which an ophthalmoscope or retinoscope is placed approximately 30cm from the eye to visualize whether a reddish hue is reflected from the retina. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C81283 Red Reflex Vision Test Red Reflex Vision Test An optic examination in which an ophthalmoscope or retinoscope is placed approximately 30cm from the eye to visualize whether a reddish hue is reflected from the retina. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C81284 Residential Telephone Number Residential Telephone Number The sequence of numbers or characters, that when dialed, connects to a particular residential telephone. C40978 Telephone Number C89506 NICHD Newborn Screening Terminology C C81284 Residential Telephone Number Residential Telephone Number The sequence of numbers or characters, that when dialed, connects to a particular residential telephone. C40978 Telephone Number C90259 NICHD Pediatric Terminology C C81288 S-Beta Thalassemia S-Beta Thalassemia A disorder characterized by the body's inability to synthesize beta-globin chains, leading to the formation of abnormal hemoglobin and anemia. This inherited autosomal recessive blood disorder is caused by germline mutation of the HBB gene. C35729 Congenital Abnormality of the Circulatory System C89506 NICHD Newborn Screening Terminology C C81288 S-Beta Thalassemia S-Beta Thalassemia A disorder characterized by the body's inability to synthesize beta-globin chains, leading to the formation of abnormal hemoglobin and anemia. This inherited autosomal recessive blood disorder is caused by germline mutation of the HBB gene. C35729 Congenital Abnormality of the Circulatory System C90259 NICHD Pediatric Terminology C C81291 Sick Newborn Sick Newborn A neonate that is unwell. C16731 Newborn C89506 NICHD Newborn Screening Terminology C C81291 Sick Newborn Sick Newborn A neonate that is unwell. C16731 Newborn C90259 NICHD Pediatric Terminology C C81298 Total Body Length Total Body Length The total linear extent of the body. C25334 Length C89506 NICHD Newborn Screening Terminology C C81298 Total Body Length Total Body Length The total linear extent of the body. C25334 Length C90259 NICHD Pediatric Terminology C C81300 Vacuum Assisted Vaginal Delivery Vacuum Assisted Vaginal Delivery The method referring to the delivery of a fetus through the vaginal canal with assistance of a vacuum extractor device. C81301 Vaginal Assisted Delivery C89506 NICHD Newborn Screening Terminology C C81300 Vacuum Assisted Vaginal Delivery Vacuum Assisted Vaginal Delivery The method referring to the delivery of a fetus through the vaginal canal with assistance of a vacuum extractor device. C81301 Vaginal Assisted Delivery C90259 NICHD Pediatric Terminology C C81300 Vacuum Assisted Vaginal Delivery Vacuum Assisted Vaginal Delivery The method referring to the delivery of a fetus through the vaginal canal with assistance of a vacuum extractor device. C81301 Vaginal Assisted Delivery C92712 NICHD Pregnancy & Childbirth Terminology C C81301 Vaginal Assisted Delivery Vaginal Assisted Delivery The method referring to the use of medical devices such as vacuum extractor or forceps to assist with the delivery of a fetus. C81303 Vaginal Delivery C89506 NICHD Newborn Screening Terminology C C81301 Vaginal Assisted Delivery Vaginal Assisted Delivery The method referring to the use of medical devices such as vacuum extractor or forceps to assist with the delivery of a fetus. C81303 Vaginal Delivery C90259 NICHD Pediatric Terminology C C81301 Vaginal Assisted Delivery Vaginal Assisted Delivery The method referring to the use of medical devices such as vacuum extractor or forceps to assist with the delivery of a fetus. C81303 Vaginal Delivery C92712 NICHD Pregnancy & Childbirth Terminology C C81302 Vaginal Birth after Cesarean Vaginal Birth after Cesarean The method referring to the delivery of a fetus through the vaginal canal after the mother has had a cesarean delivery with a previous pregnancy. C81303 Vaginal Delivery C89506 NICHD Newborn Screening Terminology C C81302 Vaginal Birth after Cesarean Vaginal Birth after Cesarean The method referring to the delivery of a fetus through the vaginal canal after the mother has had a cesarean delivery with a previous pregnancy. C81303 Vaginal Delivery C90259 NICHD Pediatric Terminology C C81302 Vaginal Birth after Cesarean Vaginal Birth after Cesarean The method referring to the delivery of a fetus through the vaginal canal after the mother has had a cesarean delivery with a previous pregnancy. C81303 Vaginal Delivery C92712 NICHD Pregnancy & Childbirth Terminology C C81306 Breathing Effort Score Breathing Effort Score A component of the APGAR score, it is the numerical value assigned to the assessment of breathing effort by a neonate. 0 = no spontaneous respirations; 1 = slow or irregular respirations or a weak cry; 2 = strong, consistent respirations with a robust cry. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C C81306 Breathing Effort Score Breathing Effort Score A component of the APGAR score, it is the numerical value assigned to the assessment of breathing effort by a neonate. 0 = no spontaneous respirations; 1 = slow or irregular respirations or a weak cry; 2 = strong, consistent respirations with a robust cry. C81274 Numeric Value C90259 NICHD Pediatric Terminology C C81309 Heart Rate Score Heart Rate Score A component of the APGAR score, it is the numerical value assigned to an assessment of the circulatory status of a neonate. 0 = no pulse; 1 = rate less than 100 beats per minute; 2 = rate greater than 100 beats per minute. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C C81309 Heart Rate Score Heart Rate Score A component of the APGAR score, it is the numerical value assigned to an assessment of the circulatory status of a neonate. 0 = no pulse; 1 = rate less than 100 beats per minute; 2 = rate greater than 100 beats per minute. C81274 Numeric Value C90259 NICHD Pediatric Terminology C C81310 Lasso-O Measuring Tape Lasso-O Measuring Tape A measuring tape frequently used to measure head circumference in newborns. C81261 Measuring Tape C89506 NICHD Newborn Screening Terminology C C81310 Lasso-O Measuring Tape Lasso-O Measuring Tape A measuring tape frequently used to measure head circumference in newborns. C81261 Measuring Tape C90259 NICHD Pediatric Terminology C C81312 Muscle Tone Score Muscle Tone Score A component of the APGAR score, it is the numerical value assigned to an assessment of the residual muscle tension of a neonate. 0 = flaccid; 1 = flexion of extremities; 2 = active motion. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C C81312 Muscle Tone Score Muscle Tone Score A component of the APGAR score, it is the numerical value assigned to an assessment of the residual muscle tension of a neonate. 0 = flaccid; 1 = flexion of extremities; 2 = active motion. C81274 Numeric Value C90259 NICHD Pediatric Terminology C C81313 Neurologic Examination Neurologic Examination The assessment of the functionality of the brain, spinal column, and nerves. C18020 Diagnostic Procedure C89506 NICHD Newborn Screening Terminology C C81313 Neurologic Examination Neurologic Examination The assessment of the functionality of the brain, spinal column, and nerves. C18020 Diagnostic Procedure C90259 NICHD Pediatric Terminology C C81314 Newborn Behavioral Examination Newborn Behavioral Examination The assessment of behavior in neonates. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C81314 Newborn Behavioral Examination Newborn Behavioral Examination The assessment of behavior in neonates. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C81319 Reflex Irritability Score Reflex Irritability Score A component of the APGAR score, it is the numerical value assigned to the neonate's response to stimuli, such as a mild pinch. 0 = no reaction; 1 = grimace; 2 = grimace with a cough, sneeze, or vigorous cry. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C C81319 Reflex Irritability Score Reflex Irritability Score A component of the APGAR score, it is the numerical value assigned to the neonate's response to stimuli, such as a mild pinch. 0 = no reaction; 1 = grimace; 2 = grimace with a cough, sneeze, or vigorous cry. C81274 Numeric Value C90259 NICHD Pediatric Terminology C C81321 Skin Color Score Skin Color Score A component of the APGAR score, it is the numerical value assigned to an assessment of the color of the skin of a neonate. 0 = pale blue; 1 = pink body and pale blue extremities; 2 = pink body and extremities. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C C81321 Skin Color Score Skin Color Score A component of the APGAR score, it is the numerical value assigned to an assessment of the color of the skin of a neonate. 0 = pale blue; 1 = pink body and pale blue extremities; 2 = pink body and extremities. C81274 Numeric Value C90259 NICHD Pediatric Terminology C C81325 Transferase Deficiency Galactosemia Transferase Deficient Galactosemia A disorder characterized by the body's inability to metabolize galactose. This type of galactosemia is caused by germline mutations in the GALT gene which leads to the inhibition in the activity of the enzyme galactose-1-phosphate uridyl transferase. C34816 Congenital Metabolic Disorder C89506 NICHD Newborn Screening Terminology C C81325 Transferase Deficiency Galactosemia Transferase Deficient Galactosemia A disorder characterized by the body's inability to metabolize galactose. This type of galactosemia is caused by germline mutations in the GALT gene which leads to the inhibition in the activity of the enzyme galactose-1-phosphate uridyl transferase. C34816 Congenital Metabolic Disorder C90259 NICHD Pediatric Terminology C C81328 Body Weight Body Weight The weight of a subject. C25447 Characteristic C89506 NICHD Newborn Screening Terminology C C81328 Body Weight Body Weight The weight of a subject. C25447 Characteristic C90259 NICHD Pediatric Terminology C C84449 Pediatric Obesity Childhood Obesity Having a high amount of body fat during childhood. C89328 Pediatric Disease or Disorder C90259 NICHD Pediatric Terminology C C84480 Heart Murmur Heart Murmur A periodic humming or blowing sound heard on auscultation of the heart that can indicate the presence of cardiac disease; murmurs are the result of vibrations caused by the turbulent flow of blood in the heart or great vessels. Murmurs are characterized according to the area of generation (mitral, aortic, tricuspid, or pulmonary) and according to the period of the cycle (systolic or diastolic). C2931 Cardiovascular Disorder C89506 NICHD Newborn Screening Terminology C C84480 Heart Murmur Heart Murmur A periodic humming or blowing sound heard on auscultation of the heart that can indicate the presence of cardiac disease; murmurs are the result of vibrations caused by the turbulent flow of blood in the heart or great vessels. Murmurs are characterized according to the area of generation (mitral, aortic, tricuspid, or pulmonary) and according to the period of the cycle (systolic or diastolic). C2931 Cardiovascular Disorder C90259 NICHD Pediatric Terminology C C84641 Clubfoot Clubfoot The most common congenital deformation of the foot, occurring in 1 of 1,000 live births. The most common form is talipes equinovarus, where the deformed foot is turned downward and inward sharply. C89337 Congenital Abnormality of the Musculoskeletal System C89506 NICHD Newborn Screening Terminology C C84641 Clubfoot Clubfoot The most common congenital deformation of the foot, occurring in 1 of 1,000 live births. The most common form is talipes equinovarus, where the deformed foot is turned downward and inward sharply. C89337 Congenital Abnormality of the Musculoskeletal System C90259 NICHD Pediatric Terminology C C84669 Dextrocardia Dextrocardia A rare congenital abnormality in which the heart is located in the right side of the chest. It is associated with other congenital heart defects. C35729 Congenital Abnormality of the Circulatory System C89506 NICHD Newborn Screening Terminology C C84669 Dextrocardia Dextrocardia A rare congenital abnormality in which the heart is located in the right side of the chest. It is associated with other congenital heart defects. C35729 Congenital Abnormality of the Circulatory System C90259 NICHD Pediatric Terminology C C84687 Encephalocele Encephalocele A congenital neural tube closure defect resulting in the protrusion of the brain through a skull opening. When the protrusion includes the meninges, the term encephalomeningocele is used. C84923 Neural Tube Defect C89506 NICHD Newborn Screening Terminology C C84687 Encephalocele Encephalocele A congenital neural tube closure defect resulting in the protrusion of the brain through a skull opening. When the protrusion includes the meninges, the term encephalomeningocele is used. C84923 Neural Tube Defect C90259 NICHD Pediatric Terminology C C84749 Newborn Examination Newborn Examination A general assessment of the overall health of a newborn. C90341 Pediatric Intervention or Procedure C89506 NICHD Newborn Screening Terminology C C84749 Newborn Examination Newborn Examination A general assessment of the overall health of a newborn. C90341 Pediatric Intervention or Procedure C90259 NICHD Pediatric Terminology C C84750 HELLP Syndrome HELLP Syndrome A life-threatening complication of pregnancy usually occurring in women with preeclampsia or eclampsia. It is characterized by hemolytic anemia, elevated liver enzymes, and low platelet count. Signs and symptoms include headaches, nausea, vomiting, blurred vision, and upper abdominal pain. It may lead to diffuse intravascular coagulation and acute renal failure. C85021 Preeclampsia C89506 NICHD Newborn Screening Terminology C C84750 HELLP Syndrome HELLP Syndrome A life-threatening complication of pregnancy usually occurring in women with preeclampsia or eclampsia. It is characterized by hemolytic anemia, elevated liver enzymes, and low platelet count. Signs and symptoms include headaches, nausea, vomiting, blurred vision, and upper abdominal pain. It may lead to diffuse intravascular coagulation and acute renal failure. C85021 Preeclampsia C90259 NICHD Pediatric Terminology C C84750 HELLP Syndrome HELLP Syndrome A life-threatening complication of pregnancy usually occurring in women with preeclampsia or eclampsia. It is characterized by hemolytic anemia, elevated liver enzymes, and low platelet count. Signs and symptoms include headaches, nausea, vomiting, blurred vision, and upper abdominal pain. It may lead to diffuse intravascular coagulation and acute renal failure. C85021 Preeclampsia C92712 NICHD Pregnancy & Childbirth Terminology C C84923 Neural Tube Defect Neural Tube Defect A congenital defect characterized by failure of the neural tube to close completely; this results in the presence of openings in the brain or spinal cord. Examples of neural tube defects include encephalocele and spina bifida. C97172 Congenital Abnormality of the Nervous System C89506 NICHD Newborn Screening Terminology C C84923 Neural Tube Defect Neural Tube Defect A congenital defect characterized by failure of the neural tube to close completely; this results in the presence of openings in the brain or spinal cord. Examples of neural tube defects include encephalocele and spina bifida. C97172 Congenital Abnormality of the Nervous System C90259 NICHD Pediatric Terminology C C85021 Preeclampsia Preeclampsia A pregnancy-related disorder characterized by an increase in the blood pressure after the twentieth week of gestation, and by the presence of proteinuria. It may appear up to six weeks post-partum. It may lead to eclampsia with development of tonic-clonic seizures. C9243 C89506 NICHD Newborn Screening Terminology C C85021 Preeclampsia Preeclampsia A pregnancy-related disorder characterized by an increase in the blood pressure after the twentieth week of gestation, and by the presence of proteinuria. It may appear up to six weeks post-partum. It may lead to eclampsia with development of tonic-clonic seizures. C9243 C90259 NICHD Pediatric Terminology C C85021 Preeclampsia Preeclampsia A pregnancy-related disorder characterized by an increase in the blood pressure after the twentieth week of gestation, and by the presence of proteinuria. It may appear up to six weeks post-partum. It may lead to eclampsia with development of tonic-clonic seizures. C9243 C92712 NICHD Pregnancy & Childbirth Terminology C C85051 Rubella Infection Rubella Infection German Measles A viral infection caused by the rubella virus. It is initially manifested with flu-like symptoms that last one or two days, followed by the development of a characteristic red rash which lasts from one to five days. The rash first appears in the neck and face. It subsequently spreads to the rest of the body. C3439 Viral Disease C90259 NICHD Pediatric Terminology C C85051 Rubella Infection Rubella Infection German Measles A viral infection caused by the rubella virus. It is initially manifested with flu-like symptoms that last one or two days, followed by the development of a characteristic red rash which lasts from one to five days. The rash first appears in the neck and face. It subsequently spreads to the rest of the body. C3439 Viral Disease C92712 NICHD Pregnancy & Childbirth Terminology C C85189 Thyroglossal Duct Cyst Thyroglossal Duct Cyst A congenital benign cyst arising from the remnants of the thyroglossal duct. It is usually located in the midline of the neck. C2978 Cyst C89506 NICHD Newborn Screening Terminology C C85189 Thyroglossal Duct Cyst Thyroglossal Duct Cyst A congenital benign cyst arising from the remnants of the thyroglossal duct. It is usually located in the midline of the neck. C2978 Cyst C90259 NICHD Pediatric Terminology C C85573 Auscultation Auscultation Listening with a device, such as a stethoscope, to anatomical locations that produce audible sounds like the heart, lungs and abdomen. C18020 Diagnostic Procedure C90259 NICHD Pediatric Terminology C C85573 Auscultation Auscultation Listening with a device, such as a stethoscope, to anatomical locations that produce audible sounds like the heart, lungs and abdomen. C18020 Diagnostic Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C87068 Circumcision Circumcision Surgical removal of the prepuce (foreskin) of a male; the foreskin is the fold of skin covering the glans of the penis. C15329 Surgical Procedure C89506 NICHD Newborn Screening Terminology C C87068 Circumcision Circumcision Surgical removal of the prepuce (foreskin) of a male; the foreskin is the fold of skin covering the glans of the penis. C15329 Surgical Procedure C90259 NICHD Pediatric Terminology C C87069 Cleft Palate Cleft Palate A congenital abnormality consisting of a fissure in the midline of the hard and/or soft palate; it is the result of the failure of the two sides of the palate to fuse during embryonic development. C97171 Congenital Abnormality of the Digestive System C89506 NICHD Newborn Screening Terminology C C87069 Cleft Palate Cleft Palate A congenital abnormality consisting of a fissure in the midline of the hard and/or soft palate; it is the result of the failure of the two sides of the palate to fuse during embryonic development. C97171 Congenital Abnormality of the Digestive System C90259 NICHD Pediatric Terminology C C87070 Hypotonia Hypotonia A condition of decreased tone of the skeletal muscles and diminished resistance to passive stretching. C4876 Symptom C89506 NICHD Newborn Screening Terminology C C87070 Hypotonia Hypotonia A condition of decreased tone of the skeletal muscles and diminished resistance to passive stretching. C4876 Symptom C90259 NICHD Pediatric Terminology C C87071 Ear Dimple Ear Dimple A pit or dimple in front of the ear of a newborn is a common finding; rarely, such a dimple may get infected, which will be manifested with redness and swelling and will require medical attention. C97174 Congenital Abnormality of the Skin C89506 NICHD Newborn Screening Terminology C C87071 Ear Dimple Ear Dimple A pit or dimple in front of the ear of a newborn is a common finding; rarely, such a dimple may get infected, which will be manifested with redness and swelling and will require medical attention. C97174 Congenital Abnormality of the Skin C90259 NICHD Pediatric Terminology C C87072 Esophageal Atresia Esophageal Atresia A congenital abnormality of the esophagus in which the upper esophagus ends as a blind pouch and does not connect with the lower esophagus; it is often accompanied by a tracheoesophageal fistula. Signs and symptoms in a newborn with this abnormality include excessive salivation, choking, coughing, and the development of cyanosis and respiratory distress when fed. C97171 Congenital Abnormality of the Digestive System C89506 NICHD Newborn Screening Terminology C C87072 Esophageal Atresia Esophageal Atresia A congenital abnormality of the esophagus in which the upper esophagus ends as a blind pouch and does not connect with the lower esophagus; it is often accompanied by a tracheoesophageal fistula. Signs and symptoms in a newborn with this abnormality include excessive salivation, choking, coughing, and the development of cyanosis and respiratory distress when fed. C97171 Congenital Abnormality of the Digestive System C90259 NICHD Pediatric Terminology C C87074 Ophthalmic Prophylaxis Eye prophylaxis The practice of placing antibiotic eye drops or ointment in a neonate's eyes after birth. C49236 Therapeutic Procedure C89506 NICHD Newborn Screening Terminology C C87074 Ophthalmic Prophylaxis Eye prophylaxis The practice of placing antibiotic eye drops or ointment in a neonate's eyes after birth. C49236 Therapeutic Procedure C90259 NICHD Pediatric Terminology C C87077 Fused Eyelid Fused Eyelid A congenital abnormality in which the margins of the upper and lower eyelids are fused together by bands of tissue. C97174 Congenital Abnormality of the Skin C89506 NICHD Newborn Screening Terminology C C87077 Fused Eyelid Fused Eyelid A congenital abnormality in which the margins of the upper and lower eyelids are fused together by bands of tissue. C97174 Congenital Abnormality of the Skin C90259 NICHD Pediatric Terminology C C87081 Heart Rhythm Heart Rhythm The recurrent, measured movements (rhythm) of a beating heart. C25447 Characteristic C89506 NICHD Newborn Screening Terminology C C87081 Heart Rhythm Heart Rhythm The recurrent, measured movements (rhythm) of a beating heart. C25447 Characteristic C90259 NICHD Pediatric Terminology C C87083 Heterotaxia Heterotaxia The abnormal arrangement or position of thoracic and/or abdominal organs in relation to each other, often occurring in a right/left transposition. C97151 Systemic Congenital Disorder C89506 NICHD Newborn Screening Terminology C C87083 Heterotaxia Heterotaxia The abnormal arrangement or position of thoracic and/or abdominal organs in relation to each other, often occurring in a right/left transposition. C97151 Systemic Congenital Disorder C90259 NICHD Pediatric Terminology C C87085 Hypertonia Hypertonia A condition of increased muscle tone manifested by increased resistance of the muscle to passive stretching. C4876 Symptom C89506 NICHD Newborn Screening Terminology C C87085 Hypertonia Hypertonia A condition of increased muscle tone manifested by increased resistance of the muscle to passive stretching. C4876 Symptom C90259 NICHD Pediatric Terminology C C87089 Irregular Respiration Irregular Breathing A change from the normal breathing pattern in an infant, child, or adult, in terms of the amplitude and frequency of inhalations and exhalations. C4876 Symptom C89506 NICHD Newborn Screening Terminology C C87089 Irregular Respiration Irregular Breathing A change from the normal breathing pattern in an infant, child, or adult, in terms of the amplitude and frequency of inhalations and exhalations. C4876 Symptom C90259 NICHD Pediatric Terminology C C87090 Labial Fusion Labial Fusion Usually found in girls between 6 months and 6 years of age, this condition occurs wherein the labia grow together instead of as 2 separate folds, thereby blocking the opening of the vagina. It is caused by conditions such as repeated diaper rash, urine and stool infections, and sexual abuse. The condition often spontaneously corrects or responds to the application of estrogen cream. C35107 Congenital Abnormality of the Genitourinary System C89506 NICHD Newborn Screening Terminology C C87090 Labial Fusion Labial Fusion Usually found in girls between 6 months and 6 years of age, this condition occurs wherein the labia grow together instead of as 2 separate folds, thereby blocking the opening of the vagina. It is caused by conditions such as repeated diaper rash, urine and stool infections, and sexual abuse. The condition often spontaneously corrects or responds to the application of estrogen cream. C35107 Congenital Abnormality of the Genitourinary System C90259 NICHD Pediatric Terminology C C87092 Large for Gestational Age Large for Gestational Age A fetus or infant who is larger than expected for the age or gender, or who has a birthweight greater than the 90th percentile. C25447 Characteristic C89506 NICHD Newborn Screening Terminology C C87092 Large for Gestational Age Large for Gestational Age A fetus or infant who is larger than expected for the age or gender, or who has a birthweight greater than the 90th percentile. C25447 Characteristic C90259 NICHD Pediatric Terminology C C87092 Large for Gestational Age Large for Gestational Age A fetus or infant who is larger than expected for the age or gender, or who has a birthweight greater than the 90th percentile. C25447 Characteristic C92712 NICHD Pregnancy & Childbirth Terminology C C87093 Meconium Aspiration Syndrome Meconium Aspiration Syndrome A serious condition in which a newborn breathes a mixture of meconium (the first intestinal discharge) and amniotic fluid into the lungs around the time of delivery. Meconium aspiration syndrome occurs in 5-10 percent of births and typically occurs when the infant is stressed, as when the infant is past its due date. C97173 Congenital Abnormality of the Respiratory System C89506 NICHD Newborn Screening Terminology C C87093 Meconium Aspiration Syndrome Meconium Aspiration Syndrome A serious condition in which a newborn breathes a mixture of meconium (the first intestinal discharge) and amniotic fluid into the lungs around the time of delivery. Meconium aspiration syndrome occurs in 5-10 percent of births and typically occurs when the infant is stressed, as when the infant is past its due date. C97173 Congenital Abnormality of the Respiratory System C90259 NICHD Pediatric Terminology C C87093 Meconium Aspiration Syndrome Meconium Aspiration Syndrome A serious condition in which a newborn breathes a mixture of meconium (the first intestinal discharge) and amniotic fluid into the lungs around the time of delivery. Meconium aspiration syndrome occurs in 5-10 percent of births and typically occurs when the infant is stressed, as when the infant is past its due date. C97173 Congenital Abnormality of the Respiratory System C92712 NICHD Pregnancy & Childbirth Terminology C C87094 Micrognathism Micrognathism A congenital abnormality of the jaws (particularly the mandible) in which they are unusually small. This condition is not always pathological and may correct itself as the patient matures; however, it may also present as a birth defect in multiple syndromes. C89337 Congenital Abnormality of the Musculoskeletal System C89506 NICHD Newborn Screening Terminology C C87094 Micrognathism Micrognathism A congenital abnormality of the jaws (particularly the mandible) in which they are unusually small. This condition is not always pathological and may correct itself as the patient matures; however, it may also present as a birth defect in multiple syndromes. C89337 Congenital Abnormality of the Musculoskeletal System C90259 NICHD Pediatric Terminology C C87096 Movement of Lip Corners Movement of Lip Corners During examination of the newborn infant, the examiner looks for symmetric movement of the lip corners. Movement of the lip corners is governed by the zygomatic major muscle. C4876 Symptom C89506 NICHD Newborn Screening Terminology C C87096 Movement of Lip Corners Movement of Lip Corners During examination of the newborn infant, the examiner looks for symmetric movement of the lip corners. Movement of the lip corners is governed by the zygomatic major muscle. C4876 Symptom C90259 NICHD Pediatric Terminology C C87101 Neonatal Abstinence Syndrome Neonatal Abstinence Syndrome A constellation of signs and symptoms observable in a neonate that are consistent with maternal substance abuse or withdrawal while pregnant. C97151 Systemic Congenital Disorder C89506 NICHD Newborn Screening Terminology C C87101 Neonatal Abstinence Syndrome Neonatal Abstinence Syndrome A constellation of signs and symptoms observable in a neonate that are consistent with maternal substance abuse or withdrawal while pregnant. C97151 Systemic Congenital Disorder C90259 NICHD Pediatric Terminology C C87103 Newborn Heart Rate Newborn Heart Rate The number of heartbeats of the newborn per minute; the normal range is 100 - 180 heartbeats per minute. C49677 Heart Rate C89506 NICHD Newborn Screening Terminology C C87103 Newborn Heart Rate Newborn Heart Rate The number of heartbeats of the newborn per minute; the normal range is 100 - 180 heartbeats per minute. C49677 Heart Rate C90259 NICHD Pediatric Terminology C C87104 Newborn Respiratory Rate Newborn Respiratory Rate The number of inhalations and exhalations of the newborn per minute; the normal range is 30 - 60 breaths per minute. C49678 Respiratory Rate C89506 NICHD Newborn Screening Terminology C C87104 Newborn Respiratory Rate Newborn Respiratory Rate The number of inhalations and exhalations of the newborn per minute; the normal range is 30 - 60 breaths per minute. C49678 Respiratory Rate C90259 NICHD Pediatric Terminology C C87105 Newborn Blood Pressure Newborn Blood Pressure The systolic and diastolic blood pressure of the newborn upon examination; the normal range of the systolic blood pressure is 60 - 90, while the normal range of the diastolic blood pressure is 20-60. C81274 Numeric Value C89506 NICHD Newborn Screening Terminology C C87105 Newborn Blood Pressure Newborn Blood Pressure The systolic and diastolic blood pressure of the newborn upon examination; the normal range of the systolic blood pressure is 60 - 90, while the normal range of the diastolic blood pressure is 20-60. C81274 Numeric Value C90259 NICHD Pediatric Terminology C C87110 Polydactyly Polydactyly A congenital abnormality characterized by more than 5 digits on a hand or foot. C89337 Congenital Abnormality of the Musculoskeletal System C89506 NICHD Newborn Screening Terminology C C87110 Polydactyly Polydactyly A congenital abnormality characterized by more than 5 digits on a hand or foot. C89337 Congenital Abnormality of the Musculoskeletal System C90259 NICHD Pediatric Terminology C C87113 Premature Rupture of Membrane Premature Rupture of Membranes PROM The condition when a patient who is beyond 37 weeks gestation presents with rupture of membranes prior to the onset of labor. Rupture of membranes is diagnosed by speculum vaginal examination of the cervix and vaginal cavity, which will show pooling of fluid in the vagina or leakage of fluid from the cervix. Preterm PROM (known as PPROM) refers to a patient who has not yet reached 37 weeks gestation and presents with rupture of membranes. C34941 Pregnancy Complication C89506 NICHD Newborn Screening Terminology C C87113 Premature Rupture of Membrane Premature Rupture of Membranes PROM The condition when a patient who is beyond 37 weeks gestation presents with rupture of membranes prior to the onset of labor. Rupture of membranes is diagnosed by speculum vaginal examination of the cervix and vaginal cavity, which will show pooling of fluid in the vagina or leakage of fluid from the cervix. Preterm PROM (known as PPROM) refers to a patient who has not yet reached 37 weeks gestation and presents with rupture of membranes. C34941 Pregnancy Complication C90259 NICHD Pediatric Terminology C C87113 Premature Rupture of Membrane Premature Rupture of Membranes PROM The condition when a patient who is beyond 37 weeks gestation presents with rupture of membranes prior to the onset of labor. Rupture of membranes is diagnosed by speculum vaginal examination of the cervix and vaginal cavity, which will show pooling of fluid in the vagina or leakage of fluid from the cervix. Preterm PROM (known as PPROM) refers to a patient who has not yet reached 37 weeks gestation and presents with rupture of membranes. C34941 Pregnancy Complication C92712 NICHD Pregnancy & Childbirth Terminology C C87114 Proptosis Proptosis Abnormal protrusion of one or both eyes from the socket; causes include hyperthyroidism (particularly Graves disease); bleeding behind the eye; infection, inflammation, or tumors of the orbit; and vascular disorders. C35126 Vision Disorder C89506 NICHD Newborn Screening Terminology C C87114 Proptosis Proptosis Abnormal protrusion of one or both eyes from the socket; causes include hyperthyroidism (particularly Graves disease); bleeding behind the eye; infection, inflammation, or tumors of the orbit; and vascular disorders. C35126 Vision Disorder C90259 NICHD Pediatric Terminology C C87115 Hemolytic Disease of the Newborn Hemolytic Disease of the Newborn A disorder caused when there is a Rh-factor blood-type incompatibility between the mother and fetus, and the mother's immune system forms antibodies that attack the red blood cells of her unborn child. This disorder can only occur if the mother is Rh-negative and the fetus is Rh-positive. C35729 Congenital Abnormality of the Circulatory System C89506 NICHD Newborn Screening Terminology C C87115 Hemolytic Disease of the Newborn Hemolytic Disease of the Newborn A disorder caused when there is a Rh-factor blood-type incompatibility between the mother and fetus, and the mother's immune system forms antibodies that attack the red blood cells of her unborn child. This disorder can only occur if the mother is Rh-negative and the fetus is Rh-positive. C35729 Congenital Abnormality of the Circulatory System C90259 NICHD Pediatric Terminology C C87118 Sacral Dimple Sacral Dimple A sacral dimple, or pilonidal dimple, is a small hollow area or sinus present at birth and located just above the crease of the buttocks. In most cases, pilonidal dimples are benign and may just be accompanied by increased hair growth in the area. C97174 Congenital Abnormality of the Skin C89506 NICHD Newborn Screening Terminology C C87118 Sacral Dimple Sacral Dimple A sacral dimple, or pilonidal dimple, is a small hollow area or sinus present at birth and located just above the crease of the buttocks. In most cases, pilonidal dimples are benign and may just be accompanied by increased hair growth in the area. C97174 Congenital Abnormality of the Skin C90259 NICHD Pediatric Terminology C C87120 Single Palmar Crease Single Palmar Crease A single transverse palmar crease is found in 5% of newborns and is frequently inherited as a familial trait. However, single palmar creases can be associated with Down's syndrome and other genetic disorders, or with fetal alcohol syndrome. C97174 Congenital Abnormality of the Skin C89506 NICHD Newborn Screening Terminology C C87120 Single Palmar Crease Single Palmar Crease A single transverse palmar crease is found in 5% of newborns and is frequently inherited as a familial trait. However, single palmar creases can be associated with Down's syndrome and other genetic disorders, or with fetal alcohol syndrome. C97174 Congenital Abnormality of the Skin C90259 NICHD Pediatric Terminology C C87121 Situs Inversus Situs Inversus A congenital condition in which there is complete right-to-left reversal of the position of the major thoracic and abdominal organs (that is, they are arranged in a mirror image of the normal positioning). C97151 Systemic Congenital Disorder C89506 NICHD Newborn Screening Terminology C C87121 Situs Inversus Situs Inversus A congenital condition in which there is complete right-to-left reversal of the position of the major thoracic and abdominal organs (that is, they are arranged in a mirror image of the normal positioning). C97151 Systemic Congenital Disorder C90259 NICHD Pediatric Terminology C C87125 Syndactyly Syndactyly A congenital condition characterized by webbing between the fingers and/or toes, joining the digits together. In rare cases, the joining of the fingers or toes may involve bony fusion between the digits. Common causes include Down Syndrome and hereditary syndactyly. C89337 Congenital Abnormality of the Musculoskeletal System C89506 NICHD Newborn Screening Terminology C C87125 Syndactyly Syndactyly A congenital condition characterized by webbing between the fingers and/or toes, joining the digits together. In rare cases, the joining of the fingers or toes may involve bony fusion between the digits. Common causes include Down Syndrome and hereditary syndactyly. C89337 Congenital Abnormality of the Musculoskeletal System C90259 NICHD Pediatric Terminology C C87130 Pterygium Colli Pterygium Colli A congenital, usually bilateral, thick web-like fold of skin that extends from the acromion to the mastoid process. This deformity is associated with Turner Syndrome and Noonan Syndrome. C97174 Congenital Abnormality of the Skin C90259 NICHD Pediatric Terminology C C87167 Eclampsia Eclampsia A potentially life-threatening disorder in pregnant or puerperal women manifested by convulsions in association with hypertension, edema, and/or proteinuria. C27020 Female Reproductive System Disorder C89506 NICHD Newborn Screening Terminology C C87167 Eclampsia Eclampsia A potentially life-threatening disorder in pregnant or puerperal women manifested by convulsions in association with hypertension, edema, and/or proteinuria. C27020 Female Reproductive System Disorder C90259 NICHD Pediatric Terminology C C87167 Eclampsia Eclampsia A potentially life-threatening disorder in pregnant or puerperal women manifested by convulsions in association with hypertension, edema, and/or proteinuria. C27020 Female Reproductive System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C87168 Group B Streptococcal Infection Group B Streptococcal Infection Group B Streptococcus, also known as Streptococcus agalactiae, colonizes the vaginal and gastrointestinal tracts of up to 45% of healthy women and may infect neonates in utero or during delivery, causing neonatal sepsis in 1-2% of colonized neonates. GBS infection may also occur in nonpregnant (particularly elderly) adults with underlying medical conditions, presenting as urinary tract infection, pneumonia, or soft-tissue infection. C2890 Bacterial Disease C89506 NICHD Newborn Screening Terminology C C87168 Group B Streptococcal Infection Group B Streptococcal Infection Group B Streptococcus, also known as Streptococcus agalactiae, colonizes the vaginal and gastrointestinal tracts of up to 45% of healthy women and may infect neonates in utero or during delivery, causing neonatal sepsis in 1-2% of colonized neonates. GBS infection may also occur in nonpregnant (particularly elderly) adults with underlying medical conditions, presenting as urinary tract infection, pneumonia, or soft-tissue infection. C2890 Bacterial Disease C90259 NICHD Pediatric Terminology C C87175 Cleft Lip Cleft Lip A congenital abnormality consisting of one or more clefts (splits) in the upper lip, which may be accompanied by a cleft palate; it is the result of the failure of the embryonic parts of the lip to fuse. C97171 Congenital Abnormality of the Digestive System C89506 NICHD Newborn Screening Terminology C C87175 Cleft Lip Cleft Lip A congenital abnormality consisting of one or more clefts (splits) in the upper lip, which may be accompanied by a cleft palate; it is the result of the failure of the embryonic parts of the lip to fuse. C97171 Congenital Abnormality of the Digestive System C90259 NICHD Pediatric Terminology C C89328 Non-Neoplastic Pediatric Disorder Pediatric Disease or Disorder A non-neoplastic disease that typically manifests prior to adulthood. C2991 Disease or Disorder C89506 NICHD Newborn Screening Terminology C C89328 Non-Neoplastic Pediatric Disorder Pediatric Disease or Disorder A non-neoplastic disease that typically manifests prior to adulthood. C2991 Disease or Disorder C90259 NICHD Pediatric Terminology C C89329 Conduct Disorder Conduct Disorder A disorder diagnosed in childhood or adolescence age group characterized by aggressive behavior, deceitfulness, destruction of property or violation of rules that is persistent and repetitive, and within a one year period. C35470 Behavioral Disorder C90259 NICHD Pediatric Terminology C C89330 Developmental Disorder Developmental Disorder A disorder diagnosed in childhood that is marked by either physical or mental impairment or both, which in turn affects the child from achieving age related developmental milestones. C89328 Pediatric Disease or Disorder C90259 NICHD Pediatric Terminology C C89332 Eating Disorder Eating Disorder A broad group of psychological disorders with abnormal eating behaviors leading to physiological effects from overeating or insufficient food intake. C2893 Psychiatric Disorder C90259 NICHD Pediatric Terminology C C89334 Learning Disorder Learning Disorder A group of disorders that affect a person's ability to learn or process specific types of information which is in contrast to his/her apparent level of intellect. C92190 Childhood Mental Disorder C90259 NICHD Pediatric Terminology C C89337 Congenital Musculoskeletal Defect Congenital Abnormality of the Musculoskeletal System An abnormality of the musculoskeletal system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C89506 NICHD Newborn Screening Terminology C C89337 Congenital Musculoskeletal Defect Congenital Abnormality of the Musculoskeletal System An abnormality of the musculoskeletal system that is present at birth or detected in the neonatal period. C2849 Congenital Abnormality C90259 NICHD Pediatric Terminology C C89338 Neurodevelopmental Disorder Neurodevelopmental Disorder A childhood affliction that has a neurological basis and manifests as a developmental disability. C89330 Developmental Disorder C90259 NICHD Pediatric Terminology C C89339 Neurological Screening Neurological Screening A specific type of neurologic examination for early detection of disease(s) and/or disorder(s). C81313 Neurologic Examination C89506 NICHD Newborn Screening Terminology C C89339 Neurological Screening Neurological Screening A specific type of neurologic examination for early detection of disease(s) and/or disorder(s). C81313 Neurologic Examination C90259 NICHD Pediatric Terminology C C89343 Finnegan Score Measurement Finnegan Score Measurement A tool to evaluate neonatal abstinence syndrome (NAS), that measures the degree to which a neonate is experiencing symptoms of withdrawal due to maternal substance abuse. C89515 Neonatal Abstinence Syndrome Assessment C89506 NICHD Newborn Screening Terminology C C89343 Finnegan Score Measurement Finnegan Score Measurement A tool to evaluate neonatal abstinence syndrome (NAS), that measures the degree to which a neonate is experiencing symptoms of withdrawal due to maternal substance abuse. C89515 Neonatal Abstinence Syndrome Assessment C90259 NICHD Pediatric Terminology C C89512 Barlow's Maneuver Barlow's Maneuver Useful in assessing for developmental dysplasia of the hip, this test is performed when the thigh is pushed posteriorly and the hip is adducted. Should the hip become dislocated by this movement, the result is considered positive. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C89512 Barlow's Maneuver Barlow's Maneuver Useful in assessing for developmental dysplasia of the hip, this test is performed when the thigh is pushed posteriorly and the hip is adducted. Should the hip become dislocated by this movement, the result is considered positive. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C89513 Heel to Ear Measurement Heel to Ear Measurement Useful in assessing neonatal neuromuscular development, this is obtained when the infant is placed in a supine position and the infant's feet are grasped pulled toward the ipsilateral ears. The examiner measures the angle made by the arc from the table to the infant's heels; increased angle for age suggests hypotonia, and decreased angle for age suggests hypertonia. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C89513 Heel to Ear Measurement Heel to Ear Measurement Useful in assessing neonatal neuromuscular development, this is obtained when the infant is placed in a supine position and the infant's feet are grasped pulled toward the ipsilateral ears. The examiner measures the angle made by the arc from the table to the infant's heels; increased angle for age suggests hypotonia, and decreased angle for age suggests hypertonia. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C89514 Palmar Crease Examination Inspection of palm crease When examining the infant's palm for abnormalities, the examiner may note a single transverse palmar crease, which is found in 5% of newborns and is frequently inherited as a familial trait. However, single palmar creases can be associated with Down's syndrome and other genetic disorders, or with fetal alcohol syndrome. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C89514 Palmar Crease Examination Inspection of palm crease When examining the infant's palm for abnormalities, the examiner may note a single transverse palmar crease, which is found in 5% of newborns and is frequently inherited as a familial trait. However, single palmar creases can be associated with Down's syndrome and other genetic disorders, or with fetal alcohol syndrome. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C89515 Neonatal Abstinence Syndrome Assessment Neonatal Abstinence Syndrome Assessment The measurement of the degree to which a neonate is experiencing symptoms of withdrawal due to maternal substance abuse; the score can be used to determine subsequent treatment of the infant. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C89515 Neonatal Abstinence Syndrome Assessment Neonatal Abstinence Syndrome Assessment The measurement of the degree to which a neonate is experiencing symptoms of withdrawal due to maternal substance abuse; the score can be used to determine subsequent treatment of the infant. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C89516 Neuromuscular Maturity Assessment Neuromuscular Maturity Assessment An examination of the following neonatal attributes: 1) posture; 2) the "square window" (how far the baby's hands can be flexed toward the wrist); 3) arm recoil; 4) "popliteal angle" (how far the baby's knees extend); 5) "scarf sign" (how far the baby's elbows can be moved across the chest); and 6) "heel to ear" (how far the baby's feet can be moved to the ears). It is a subscore of the Dubowitz/Ballard Examination for Gestational Age. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C89516 Neuromuscular Maturity Assessment Neuromuscular Maturity Assessment An examination of the following neonatal attributes: 1) posture; 2) the "square window" (how far the baby's hands can be flexed toward the wrist); 3) arm recoil; 4) "popliteal angle" (how far the baby's knees extend); 5) "scarf sign" (how far the baby's elbows can be moved across the chest); and 6) "heel to ear" (how far the baby's feet can be moved to the ears). It is a subscore of the Dubowitz/Ballard Examination for Gestational Age. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C89517 Ortolani Maneuver Ortolani Maneuver When testing for congenital dislocation of the hip, this is the result obtained when the examiner gently abducts the hip while pushing upward on the greater trochanter. If the hip is dislocated, it will relocate with an audible clunk, which is a positive result for this test. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C89517 Ortolani Maneuver Ortolani Maneuver When testing for congenital dislocation of the hip, this is the result obtained when the examiner gently abducts the hip while pushing upward on the greater trochanter. If the hip is dislocated, it will relocate with an audible clunk, which is a positive result for this test. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C89518 Physical Maturity Assessment Physical Maturity Assessment An examination of the following neonatal attributes: 1) skin texture; 2) lanugo; 3) plantar creases; 4) breast; 5) eyes and ears; 6) genitals, male; and 7) genitals, female. It is a subscore of the Dubowitz/Ballard Examination for Gestational Age. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C89518 Physical Maturity Assessment Physical Maturity Assessment An examination of the following neonatal attributes: 1) skin texture; 2) lanugo; 3) plantar creases; 4) breast; 5) eyes and ears; 6) genitals, male; and 7) genitals, female. It is a subscore of the Dubowitz/Ballard Examination for Gestational Age. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C89519 Popliteal Angle Measurement Popliteal Angle Measurement An examination whereby the patient is placed supine, the hip is flexed 90 degrees, and the knee is extended until firm resistance is met. The popliteal angle is the angle from the tibia to the femur. This measurement is used to assess hamstring contracture in children with cerebral palsy. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C89519 Popliteal Angle Measurement Popliteal Angle Measurement An examination whereby the patient is placed supine, the hip is flexed 90 degrees, and the knee is extended until firm resistance is met. The popliteal angle is the angle from the tibia to the femur. This measurement is used to assess hamstring contracture in children with cerebral palsy. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C89520 Square Window Square Window When testing the newborn infant for neuromuscular maturity, the "square window" test measures wrist flexibility and resistance to extensor stretching, The examiner straightens the infant's fingers and applies gentle pressure on the dorsum of the hand, close to the fingers, and then estimates the angle between the palm of the hand and the forearm. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C89520 Square Window Square Window When testing the newborn infant for neuromuscular maturity, the "square window" test measures wrist flexibility and resistance to extensor stretching, The examiner straightens the infant's fingers and applies gentle pressure on the dorsum of the hand, close to the fingers, and then estimates the angle between the palm of the hand and the forearm. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C89521 Scarf Sign Scarf Sign When testing the newborn infant for neuromuscular maturity, the "scarf sign" test is carried out by drawing the newborn's arm across the chest to the opposite shoulder until resistance is felt. In term infants, the elbow should not cross the midline of the chest. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C89521 Scarf Sign Scarf Sign When testing the newborn infant for neuromuscular maturity, the "scarf sign" test is carried out by drawing the newborn's arm across the chest to the opposite shoulder until resistance is felt. In term infants, the elbow should not cross the midline of the chest. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C9011 Dermoid Cyst Dermoid Cyst A mature teratoma characterized by the presence of a cyst which is lined by mature tissue resembling the epidermis and the epidermal appendages. It occurs in the ovary, testis, and extragonadal sites including central nervous system and skin. C2978 Cyst C89506 NICHD Newborn Screening Terminology C C9011 Dermoid Cyst Dermoid Cyst A mature teratoma characterized by the presence of a cyst which is lined by mature tissue resembling the epidermis and the epidermal appendages. It occurs in the ovary, testis, and extragonadal sites including central nervous system and skin. C2978 Cyst C90259 NICHD Pediatric Terminology C C90342 Developmental Milestone Developmental Milestones Physical or behavioral signs of maturation or skills gained by a developing child, which should be achieved by a given age that provide important information regarding the child's development. The milestones are different for each age range. Failure to achieve a particular milestone by a given age is indicative of developmental delay. C70856 Observational Result C90259 NICHD Pediatric Terminology C C90492 Personal Information Personal Information Data, facts or figures about an individual; the set of relevant items would depend on the use case. C20189 Property or Attribute C89506 NICHD Newborn Screening Terminology C C90492 Personal Information Personal Information Data, facts or figures about an individual; the set of relevant items would depend on the use case. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C C90496 Arm Recoil Arm Recoil Measurement A test commonly administered to assess the physiologic response to extending the arms as straight as possible alongside the body when lying down. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C90496 Arm Recoil Arm Recoil Measurement A test commonly administered to assess the physiologic response to extending the arms as straight as possible alongside the body when lying down. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C90497 Galeazzi Test Galeazzi Test An assessment for developmental dysplasia of the hip or a leg-length discrepancy, the patient is placed in a supine position and the ankles are brought to the buttocks with the hips and knees flexed. The result is considered positive when the knees are at different heights. C84749 Newborn Examination C89506 NICHD Newborn Screening Terminology C C90497 Galeazzi Test Galeazzi Test An assessment for developmental dysplasia of the hip or a leg-length discrepancy, the patient is placed in a supine position and the ankles are brought to the buttocks with the hips and knees flexed. The result is considered positive when the knees are at different heights. C84749 Newborn Examination C90259 NICHD Pediatric Terminology C C90498 Risk Factor Assessment Risk Factor Assessment A systematic gathering of information regarding the variables associated with an individual's increased risk of disease or infection. C25218 Intervention or Procedure C89506 NICHD Newborn Screening Terminology C C90498 Risk Factor Assessment Risk Factor Assessment A systematic gathering of information regarding the variables associated with an individual's increased risk of disease or infection. C25218 Intervention or Procedure C90259 NICHD Pediatric Terminology C C91199 Vaginal Ring Dosage Form Vaginal Ring A ring composed of active and/or inert ingredient(s), intended for administration in or around the vagina. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C C91199 Vaginal Ring Dosage Form Vaginal Ring A ring composed of active and/or inert ingredient(s), intended for administration in or around the vagina. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C C92711 Fetal Finding Fetal Finding Any intrauterine symptom or result related to the fetus. C70856 Observational Result C90259 NICHD Pediatric Terminology C C92711 Fetal Finding Fetal Finding Any intrauterine symptom or result related to the fetus. C70856 Observational Result C92712 NICHD Pregnancy & Childbirth Terminology C C92714 Fetal Examination Fetal Examination A test or diagnostic examination to assess the health status and well being of the fetus. C90341 Pediatric Intervention or Procedure C90259 NICHD Pediatric Terminology C C92714 Fetal Examination Fetal Examination A test or diagnostic examination to assess the health status and well being of the fetus. C90341 Pediatric Intervention or Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C92715 Fetal Heart Finding Fetal Heart Finding An observation of the fetal heart that may or may not be abnormal. C70856 Observational Result C90259 NICHD Pediatric Terminology C C92715 Fetal Heart Finding Fetal Heart Finding An observation of the fetal heart that may or may not be abnormal. C70856 Observational Result C92712 NICHD Pregnancy & Childbirth Terminology C C92716 Fetal Heart Rate Fetal Heart Rate The number of fetal cardiac beats per minute. C49677 Heart Rate C90259 NICHD Pediatric Terminology C C92716 Fetal Heart Rate Fetal Heart Rate The number of fetal cardiac beats per minute. C49677 Heart Rate C92712 NICHD Pregnancy & Childbirth Terminology C C92718 Finding during Childbirth Labor Finding during Childbirth Labor Symptom, signs, test results in a pregnant mother childbirth. C70856 Observational Result C90259 NICHD Pediatric Terminology C C92718 Finding during Childbirth Labor Finding during Childbirth Labor Symptom, signs, test results in a pregnant mother childbirth. C70856 Observational Result C92712 NICHD Pregnancy & Childbirth Terminology C C92721 Pregnancy Related Screening Screening or Clinical Tests during Pregnancy A group of tests performed during pregnancy to assess fetal health and to detect for genetic abnormalities and various disorders. C15843 Preventive Intervention C90259 NICHD Pediatric Terminology C C92721 Pregnancy Related Screening Screening or Clinical Tests during Pregnancy A group of tests performed during pregnancy to assess fetal health and to detect for genetic abnormalities and various disorders. C15843 Preventive Intervention C92712 NICHD Pregnancy & Childbirth Terminology C C92722 Qualitative Qualitative Concept A measurement expressed in words rather than numbers. C20189 Property or Attribute C90259 NICHD Pediatric Terminology C C92722 Qualitative Qualitative Concept A measurement expressed in words rather than numbers. C20189 Property or Attribute C92712 NICHD Pregnancy & Childbirth Terminology C C92726 Abnormal Pregnancy Abnormal Pregnancy A pregnancy that is complicated and affected by an abnormal finding or disease condition in either the fetus and/or the mother. C27020 Female Reproductive System Disorder C90259 NICHD Pediatric Terminology C C92726 Abnormal Pregnancy Abnormal Pregnancy A pregnancy that is complicated and affected by an abnormal finding or disease condition in either the fetus and/or the mother. C27020 Female Reproductive System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C92727 Alcohol Related Birth Defect Alcohol Related Birth Defects A physical or cognitive mental abnormality caused by maternal alcohol consumption and its toxic effect on the developing embryo during pregnancy. C92780 Fetal Alcohol Spectrum Disorder C90259 NICHD Pediatric Terminology C C92727 Alcohol Related Birth Defect Alcohol Related Birth Defects A physical or cognitive mental abnormality caused by maternal alcohol consumption and its toxic effect on the developing embryo during pregnancy. C92780 Fetal Alcohol Spectrum Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C92728 Alcohol Related Neurodevelopmental Disorder Alcohol Related Neurodevelopmental Disorder A cognitive and neurological disorder due to fetal intrauterine exposure to maternal alcohol consumption. Typically, this presents without facies or other growth abnormalities. C92780 Fetal Alcohol Spectrum Disorder C90259 NICHD Pediatric Terminology C C92728 Alcohol Related Neurodevelopmental Disorder Alcohol Related Neurodevelopmental Disorder A cognitive and neurological disorder due to fetal intrauterine exposure to maternal alcohol consumption. Typically, this presents without facies or other growth abnormalities. C92780 Fetal Alcohol Spectrum Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C92730 Angular Pregnancy Angular Pregnancy A type of pregnancy which starts with the embryo in the interstitial section of the fallopian tube, which then grows into the uterine cavity. C34945 Ectopic Pregnancy C90259 NICHD Pediatric Terminology C C92730 Angular Pregnancy Angular Pregnancy A type of pregnancy which starts with the embryo in the interstitial section of the fallopian tube, which then grows into the uterine cavity. C34945 Ectopic Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92732 Anterior Occiput Presentation Anterior Occiput Occiput Anterior A fetal position during delivery in which the head of the fetus faces the mother's back. C92926 Fetal Position C90259 NICHD Pediatric Terminology C C92732 Anterior Occiput Presentation Anterior Occiput Occiput Anterior A fetal position during delivery in which the head of the fetus faces the mother's back. C92926 Fetal Position C92712 NICHD Pregnancy & Childbirth Terminology C C92739 Back Labor Back Labor A type of labor where the labor pain or discomfort is felt by the pregnant mother in her back. C4876 Symptom C90259 NICHD Pediatric Terminology C C92739 Back Labor Back Labor A type of labor where the labor pain or discomfort is felt by the pregnant mother in her back. C4876 Symptom C92712 NICHD Pregnancy & Childbirth Terminology C C92740 Bacterial Vaginosis Screening Bacterial Vaginosis Screen A test done during pregnancy for the presence of Gardnerella vaginalis, Ureaplasma urealyticum, Mycoplasma hominis, Mobiluncus, Prevotella and anaerobic bacteria. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C C92740 Bacterial Vaginosis Screening Bacterial Vaginosis Screen A test done during pregnancy for the presence of Gardnerella vaginalis, Ureaplasma urealyticum, Mycoplasma hominis, Mobiluncus, Prevotella and anaerobic bacteria. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92744 Blood Glucose Measurement Blood Glucose Measurement A quantitative measurement for assessing the amount of glucose present in a blood sample. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C C92744 Blood Glucose Measurement Blood Glucose Measurement A quantitative measurement for assessing the amount of glucose present in a blood sample. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92753 Cesarean Hysterectomy Caesarean Hysterectomy Surgical removal of uterus as a concurrent procedure after a cesarean delivery. C15256 Hysterectomy C90259 NICHD Pediatric Terminology C C92753 Cesarean Hysterectomy Caesarean Hysterectomy Surgical removal of uterus as a concurrent procedure after a cesarean delivery. C15256 Hysterectomy C92712 NICHD Pregnancy & Childbirth Terminology C C92757 Contraceptive Cap Cervical Contraceptive Cap A medical device with a small rubber cap that fits over the cervix to block sperm from entering the cervical os. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C C92757 Contraceptive Cap Cervical Contraceptive Cap A medical device with a small rubber cap that fits over the cervix to block sperm from entering the cervical os. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C C92759 Contraceptive Implant Contraceptive Implant A drug implant that acts as a birth control device and which is inserted under the skin for drug delivery into the body. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C C92759 Contraceptive Implant Contraceptive Implant A drug implant that acts as a birth control device and which is inserted under the skin for drug delivery into the body. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C C92760 Contraceptive Patch Contraceptive Patch A dermal patch that contains estrogen and progestin hormones for release and absorption through the skin and into the body to prevent pregnancy. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C C92760 Contraceptive Patch Contraceptive Patch A dermal patch that contains estrogen and progestin hormones for release and absorption through the skin and into the body to prevent pregnancy. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C C92761 Cornual Pregnancy Cornual Pregnancy A type of pregnancy where the embryo develops in the cornu of uterus. C34945 Ectopic Pregnancy C90259 NICHD Pediatric Terminology C C92761 Cornual Pregnancy Cornual Pregnancy A type of pregnancy where the embryo develops in the cornu of uterus. C34945 Ectopic Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92764 Cystic Fibrosis Carrier Screening Cystic Fibrosis Carrier Screening A genetic test to determine if either parent has the trait of cystic fibrosis carrier. C92803 Screening for Genetic Defect C90259 NICHD Pediatric Terminology C C92764 Cystic Fibrosis Carrier Screening Cystic Fibrosis Carrier Screening A genetic test to determine if either parent has the trait of cystic fibrosis carrier. C92803 Screening for Genetic Defect C92712 NICHD Pregnancy & Childbirth Terminology C C92766 Delivery of Placenta Delivery of Placenta The natural process whereby the placenta detaches from the uterus. It occurs during the third stage of childbirth and shortly after delivery of the fetus. C92935 Postpartum Process C90259 NICHD Pediatric Terminology C C92766 Delivery of Placenta Delivery of Placenta The natural process whereby the placenta detaches from the uterus. It occurs during the third stage of childbirth and shortly after delivery of the fetus. C92935 Postpartum Process C92712 NICHD Pregnancy & Childbirth Terminology C C92776 External Fetal Rotation External Fetal Rotation External version A manual method of maneuvering the fetus from outside the mother's abdomen to convert a breech into a cephalic presentation. C81179 Delivery Procedure C90259 NICHD Pediatric Terminology C C92776 External Fetal Rotation External Fetal Rotation External version A manual method of maneuvering the fetus from outside the mother's abdomen to convert a breech into a cephalic presentation. C81179 Delivery Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C92779 False Labor False Labor A relatively painless, irregular tightening sensation felt by the pregnant mother over the abdomen after the 28th week of pregnancy, that lasts about a minute each time C92904 Uterine Contraction C90259 NICHD Pediatric Terminology C C92779 False Labor False Labor A relatively painless, irregular tightening sensation felt by the pregnant mother over the abdomen after the 28th week of pregnancy, that lasts about a minute each time C92904 Uterine Contraction C92712 NICHD Pregnancy & Childbirth Terminology C C92780 Fetal Alcohol Spectrum Disorder Fetal Alcohol Spectrum Disorder A group of disorders caused by a prenatal exposure to maternal consumption of alcohol leading to a range of behavioral, cognitive and neurological deficits in the offspring. It is characterized by physical growth problems, distinct facies, and varying psycho-neurological issues. C97151 Systemic Congenital Disorder C90259 NICHD Pediatric Terminology C C92780 Fetal Alcohol Spectrum Disorder Fetal Alcohol Spectrum Disorder A group of disorders caused by a prenatal exposure to maternal consumption of alcohol leading to a range of behavioral, cognitive and neurological deficits in the offspring. It is characterized by physical growth problems, distinct facies, and varying psycho-neurological issues. C97151 Systemic Congenital Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C92782 Fetal Bradycardia Fetal Bradycardia A decrease in the fetal heart rate below normal baseline values. C92716 Fetal Heart Rate C90259 NICHD Pediatric Terminology C C92782 Fetal Bradycardia Fetal Bradycardia A decrease in the fetal heart rate below normal baseline values. C92716 Fetal Heart Rate C92712 NICHD Pregnancy & Childbirth Terminology C C92786 Fetal Fibronectin Test Fetal Fibronectin Test A laboratory test to detect fetal prematurity by measuring levels of fetal fibronectin from vaginal and cervical secretions. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C C92786 Fetal Fibronectin Test Fetal Fibronectin Test A laboratory test to detect fetal prematurity by measuring levels of fetal fibronectin from vaginal and cervical secretions. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92793 Fetal Malpresentation Malpresentation of Fetus An abnormal position assumed by the fetus in the birth canal during the childbirth process. C81236 Birth Complication C90259 NICHD Pediatric Terminology C C92793 Fetal Malpresentation Malpresentation of Fetus An abnormal position assumed by the fetus in the birth canal during the childbirth process. C81236 Birth Complication C92712 NICHD Pregnancy & Childbirth Terminology C C92794 Fetal Pulse Oximetry Fetal Pulse Oximetry A method to assess fetal oxygenation status during labor and delivery using a noninvasive reflectance pulse oximeter. C92714 Fetal Examination C90259 NICHD Pediatric Terminology C C92794 Fetal Pulse Oximetry Fetal Pulse Oximetry A method to assess fetal oxygenation status during labor and delivery using a noninvasive reflectance pulse oximeter. C92714 Fetal Examination C92712 NICHD Pregnancy & Childbirth Terminology C C92796 Fetal Tachycardia Fetal Tachycardia An increase in the fetal heart rate above the normal baseline values. C92716 Fetal Heart Rate C90259 NICHD Pediatric Terminology C C92796 Fetal Tachycardia Fetal Tachycardia An increase in the fetal heart rate above the normal baseline values. C92716 Fetal Heart Rate C92712 NICHD Pregnancy & Childbirth Terminology C C92803 Genetic Screening Screening for Genetic Defect Testing to determine if there is a predisposition or indication of a possible genetic or a chromosomal abnormality. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C C92803 Genetic Screening Screening for Genetic Defect Testing to determine if there is a predisposition or indication of a possible genetic or a chromosomal abnormality. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92805 Group B Streptococcus Screening Group B Streptococcus Screening Screening with a swab from the vaginal and rectal areas in late pregnancy to test for the presence of Group B streptococcal infection. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C C92805 Group B Streptococcus Screening Group B Streptococcus Screening Screening with a swab from the vaginal and rectal areas in late pregnancy to test for the presence of Group B streptococcal infection. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92806 Hepatitis B Screening Hepatitis B Screening A test performed to determine the presence or absence of hepatitis B surface antigen. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C C92806 Hepatitis B Screening Hepatitis B Screening A test performed to determine the presence or absence of hepatitis B surface antigen. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92809 Hormone Imbalance Hormone Imbalance An abnormal finding indicating that the level of a particular hormone is not within the expected normal values. C3009 Endocrine System Disorder C90259 NICHD Pediatric Terminology C C92809 Hormone Imbalance Hormone Imbalance An abnormal finding indicating that the level of a particular hormone is not within the expected normal values. C3009 Endocrine System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C92813 Impending Labor Impending Labor The period of time prior to the beginning of childbirth labor; common signs and symptoms include nesting, anxiety, excitement, loss of mucous plug, increased urinary frequency and loose bowel movements. C21173 Reproductive Process C90259 NICHD Pediatric Terminology C C92813 Impending Labor Impending Labor The period of time prior to the beginning of childbirth labor; common signs and symptoms include nesting, anxiety, excitement, loss of mucous plug, increased urinary frequency and loose bowel movements. C21173 Reproductive Process C92712 NICHD Pregnancy & Childbirth Terminology C C92836 Non-Stress Test Non-Stress Test A non-invasive test usually done during the third trimester to check for fetal well being. It is performed using an external fetal heart rate monitor to assess the fetal heart rate response to fetal movements. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C C92836 Non-Stress Test Non-Stress Test A non-invasive test usually done during the third trimester to check for fetal well being. It is performed using an external fetal heart rate monitor to assess the fetal heart rate response to fetal movements. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92837 Nuchal Translucency Screen Nuchal Translucency Screen nuchal fold scan An ultrasonic examination of the fetus to confirm gestational age by assessing and measuring for the clear space at the back of the fetal neck using external calipers. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C C92837 Nuchal Translucency Screen Nuchal Translucency Screen nuchal fold scan An ultrasonic examination of the fetus to confirm gestational age by assessing and measuring for the clear space at the back of the fetal neck using external calipers. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92841 Perinatal Death Perinatal Death The death of an infant before birth after 28 weeks of gestation or shortly after birth. C90491 Pregnancy Outcome C90259 NICHD Pediatric Terminology C C92841 Perinatal Death Perinatal Death The death of an infant before birth after 28 weeks of gestation or shortly after birth. C90491 Pregnancy Outcome C92712 NICHD Pregnancy & Childbirth Terminology C C92842 Persistent Fetal Bradycardia Persistent Fetal Bradycardia A decrease in the fetal heart beat rate below 110 per minute or below the normal baseline value expected for the particular fetal age for a period of more than 10 minutes. C92782 Fetal Bradycardia C90259 NICHD Pediatric Terminology C C92842 Persistent Fetal Bradycardia Persistent Fetal Bradycardia A decrease in the fetal heart beat rate below 110 per minute or below the normal baseline value expected for the particular fetal age for a period of more than 10 minutes. C92782 Fetal Bradycardia C92712 NICHD Pregnancy & Childbirth Terminology C C92843 Persistent Fetal Tachycardia Persistent Fetal Tachycardia An increase in the fetal heart rate above the expected normal baseline values for an extended period. C92796 Fetal Tachycardia C90259 NICHD Pediatric Terminology C C92843 Persistent Fetal Tachycardia Persistent Fetal Tachycardia An increase in the fetal heart rate above the expected normal baseline values for an extended period. C92796 Fetal Tachycardia C92712 NICHD Pregnancy & Childbirth Terminology C C92844 Physiologic Lightening Physiologic Lightening A physical feeling of being able to breathe better during late trimester of pregnancy when the baby starts to descend lower into the pelvic cavity. C92819 Intrapartum Process C90259 NICHD Pediatric Terminology C C92844 Physiologic Lightening Physiologic Lightening A physical feeling of being able to breathe better during late trimester of pregnancy when the baby starts to descend lower into the pelvic cavity. C92819 Intrapartum Process C92712 NICHD Pregnancy & Childbirth Terminology C C92845 Placental Duncan Mechanism Duncan Mechanism The expulsion of the placenta with presentation of the maternal rough side first, rather than the usual fetal side of the placenta. C92935 Postpartum Process C90259 NICHD Pediatric Terminology C C92845 Placental Duncan Mechanism Duncan Mechanism The expulsion of the placenta with presentation of the maternal rough side first, rather than the usual fetal side of the placenta. C92935 Postpartum Process C92712 NICHD Pregnancy & Childbirth Terminology C C92847 Polycystic Ovary Syndrome Polycystic Ovary Syndrome A disorder that manifests as multiple cysts on the ovaries. It results in hormonal imbalances and leads to irregular and abnormal menstrual periods, excess growth of hair, acne eruptions and obesity. C3009 Endocrine System Disorder C90259 NICHD Pediatric Terminology C C92847 Polycystic Ovary Syndrome Polycystic Ovary Syndrome A disorder that manifests as multiple cysts on the ovaries. It results in hormonal imbalances and leads to irregular and abnormal menstrual periods, excess growth of hair, acne eruptions and obesity. C3009 Endocrine System Disorder C92712 NICHD Pregnancy & Childbirth Terminology C C92852 Postpartum Depression Postpartum Depression A type of clinical depression that occurs after childbirth. C2982 Depression C90259 NICHD Pediatric Terminology C C92852 Postpartum Depression Postpartum Depression A type of clinical depression that occurs after childbirth. C2982 Depression C92712 NICHD Pregnancy & Childbirth Terminology C C92859 Prenatal HIV Screening HIV Screening Testing of a pregnant mother for antibodies to the human immunodeficiency virus (HIV) in early pregnancy. Results permit management to reduce the chances of maternal transmission of HIV to the fetus. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C C92859 Prenatal HIV Screening HIV Screening Testing of a pregnant mother for antibodies to the human immunodeficiency virus (HIV) in early pregnancy. Results permit management to reduce the chances of maternal transmission of HIV to the fetus. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92862 Preterm Premature Rupture of Membrane Preterm Premature Rupture of Membrane PPROM An early rupture of the amniotic membranes during pregnancy and one that precedes 37 weeks of gestation. C87113 Premature Rupture of Membranes C90259 NICHD Pediatric Terminology C C92862 Preterm Premature Rupture of Membrane Preterm Premature Rupture of Membrane PPROM An early rupture of the amniotic membranes during pregnancy and one that precedes 37 weeks of gestation. C87113 Premature Rupture of Membranes C92712 NICHD Pregnancy & Childbirth Terminology C C92869 Relaxation Time between Uterine Contractions Contraction Interval Relaxation Time between Contractions The period between uterine contractions during labor when the uterine smooth muscles relax. C70766 Quantitative Concept C90259 NICHD Pediatric Terminology C C92869 Relaxation Time between Uterine Contractions Contraction Interval Relaxation Time between Contractions The period between uterine contractions during labor when the uterine smooth muscles relax. C70766 Quantitative Concept C92712 NICHD Pregnancy & Childbirth Terminology C C92873 Rubella Screening Screening for Rubella A test during pregnancy to determine maternal exposure to the rubella virus that could lead to pregnancy complications or congenital rubella syndrome in the newborn. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C C92873 Rubella Screening Screening for Rubella A test during pregnancy to determine maternal exposure to the rubella virus that could lead to pregnancy complications or congenital rubella syndrome in the newborn. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92874 Rupture of Membrane Rupture of Membrane amniorrhexis|breaking water Breaking or tearing of the amniotic membranes during childbirth leading to the leakage of amniotic fluid and the progression of labor. C92819 Intrapartum Process C90259 NICHD Pediatric Terminology C C92874 Rupture of Membrane Rupture of Membrane amniorrhexis|breaking water Breaking or tearing of the amniotic membranes during childbirth leading to the leakage of amniotic fluid and the progression of labor. C92819 Intrapartum Process C92712 NICHD Pregnancy & Childbirth Terminology C C92878 Sexually Transmitted Disease Screening Sexually Transmitted Disease Screening A test to detect the presence of a sexually transmissible disease such as HIV, chlamydia, syphilis, gonorrhea, hepatitis B or hepatitis C. C15843 Preventive Intervention C90259 NICHD Pediatric Terminology C C92878 Sexually Transmitted Disease Screening Sexually Transmitted Disease Screening A test to detect the presence of a sexually transmissible disease such as HIV, chlamydia, syphilis, gonorrhea, hepatitis B or hepatitis C. C15843 Preventive Intervention C92712 NICHD Pregnancy & Childbirth Terminology C C92882 Sinciput Presentation Sinciput A fetal position during delivery in which the frontal part of the skull including forehead and the top of the head is first to descend into the birth canal. C92926 Fetal Position C90259 NICHD Pediatric Terminology C C92882 Sinciput Presentation Sinciput A fetal position during delivery in which the frontal part of the skull including forehead and the top of the head is first to descend into the birth canal. C92926 Fetal Position C92712 NICHD Pregnancy & Childbirth Terminology C C92886 Spermicide Spermicide A chemical product that is deleterious to sperms and can be in the form of either a jelly, foam, or cream. C42734 Contraceptive Device C90259 NICHD Pediatric Terminology C C92886 Spermicide Spermicide A chemical product that is deleterious to sperms and can be in the form of either a jelly, foam, or cream. C42734 Contraceptive Device C92712 NICHD Pregnancy & Childbirth Terminology C C92889 ST Waveform Analysis ST Waveform Analysis Technology STAN A method of fetal ECG surveillance during labor that monitors the ST segment, to indicate any fetal hypoxia. C92714 Fetal Examination C90259 NICHD Pediatric Terminology C C92889 ST Waveform Analysis ST Waveform Analysis Technology STAN A method of fetal ECG surveillance during labor that monitors the ST segment, to indicate any fetal hypoxia. C92714 Fetal Examination C92712 NICHD Pregnancy & Childbirth Terminology C C92892 Surgical Contraception Surgical Contraception Method A method of achieving contraception with the aid of a surgical procedure that prevents fertilization of an egg by a sperm. C37932 Contraception C15332 Gynecologic Surgical Procedure C90259 NICHD Pediatric Terminology C C92892 Surgical Contraception Surgical Contraception Method A method of achieving contraception with the aid of a surgical procedure that prevents fertilization of an egg by a sperm. C37932 Contraception C15332 Gynecologic Surgical Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C92901 Tubal Ligation Tubal Ligation A method of female sterilization where the fallopian tubes are surgically ligated to prevent conception. C92892 Surgical Contraception Method C90259 NICHD Pediatric Terminology C C92901 Tubal Ligation Tubal Ligation A method of female sterilization where the fallopian tubes are surgically ligated to prevent conception. C92892 Surgical Contraception Method C92712 NICHD Pregnancy & Childbirth Terminology C C92908 Uterine Contraction Stress Test Contraction Stress Test A test done to check for the fetal well being after administering oxytocin or nipple stimulus to induce uterine contractions in the mother. An external fetal heart rate monitor is used to assess the fetal heart rate in response to the uterine contractions. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C C92908 Uterine Contraction Stress Test Contraction Stress Test A test done to check for the fetal well being after administering oxytocin or nipple stimulus to induce uterine contractions in the mother. An external fetal heart rate monitor is used to assess the fetal heart rate in response to the uterine contractions. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92916 Varicella Zoster Virus Screening Screening for Chickenpox A test to determine if an individual has antibodies to the varicella zoster virus. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C C92916 Varicella Zoster Virus Screening Screening for Chickenpox A test to determine if an individual has antibodies to the varicella zoster virus. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92920 Assessment of Fetal Condition Assessment of Fetal Condition A method to determine health status of fetus; it includes prenatal diagnostic methods and obstetrical management. C90341 Pediatric Intervention or Procedure C90259 NICHD Pediatric Terminology C C92920 Assessment of Fetal Condition Assessment of Fetal Condition A method to determine health status of fetus; it includes prenatal diagnostic methods and obstetrical management. C90341 Pediatric Intervention or Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C92921 Abdominal Pregnancy Abdominal Pregnancy Ectopic pregnancy characterized by the implantation of the embryo in the peritoneal cavity or abdominal organs. C34945 Ectopic Pregnancy C90259 NICHD Pediatric Terminology C C92921 Abdominal Pregnancy Abdominal Pregnancy Ectopic pregnancy characterized by the implantation of the embryo in the peritoneal cavity or abdominal organs. C34945 Ectopic Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92922 Cardiotocography Intrapartum Cardiotocography Electronic fetal monitoring|continuous cardiotocography (CTG)|intrapartum CTG The monitoring of both maternal uterine contractions and fetal heart rate during the process of labor and delivery. C92714 Fetal Examination C90259 NICHD Pediatric Terminology C C92922 Cardiotocography Intrapartum Cardiotocography Electronic fetal monitoring|continuous cardiotocography (CTG)|intrapartum CTG The monitoring of both maternal uterine contractions and fetal heart rate during the process of labor and delivery. C92714 Fetal Examination C92712 NICHD Pregnancy & Childbirth Terminology C C92923 Development of Corpus Luteum Development of Corpus Luteum The process by which the ovarian follicle becomes the corpus luteum. It occurs after ovulation. C21173 Reproductive Process C90259 NICHD Pediatric Terminology C C92923 Development of Corpus Luteum Development of Corpus Luteum The process by which the ovarian follicle becomes the corpus luteum. It occurs after ovulation. C21173 Reproductive Process C92712 NICHD Pregnancy & Childbirth Terminology C C92925 Fetal Biophysical Profile Fetal Biophysical Profile A clinical scoring method to monitor fetal asphyxia using four ultrasonic observations that include fetal breathing, fetal body movements, fetal tone, and amniotic fluid volume. Also included is the non-stress test derived fetal heart rate response to fetal movements. C92721 Screening or Clinical Tests during Pregnancy C90259 NICHD Pediatric Terminology C C92925 Fetal Biophysical Profile Fetal Biophysical Profile A clinical scoring method to monitor fetal asphyxia using four ultrasonic observations that include fetal breathing, fetal body movements, fetal tone, and amniotic fluid volume. Also included is the non-stress test derived fetal heart rate response to fetal movements. C92721 Screening or Clinical Tests during Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92929 Fetal Heart Rate Monitoring Fetal Heart Rate Monitoring The act of observing and recording the fetal heart rate for determining the baseline values and any variations or other abnormal tracings. C92714 Fetal Examination C90259 NICHD Pediatric Terminology C C92929 Fetal Heart Rate Monitoring Fetal Heart Rate Monitoring The act of observing and recording the fetal heart rate for determining the baseline values and any variations or other abnormal tracings. C92714 Fetal Examination C92712 NICHD Pregnancy & Childbirth Terminology C C92945 Ovarian Pregnancy Ovarian Pregnancy An ectopic pregnancy of unknown etiology that occurs in the ovary instead of the uterine corpus. It may result in severe intra-abdominal bleeding. C34945 Ectopic Pregnancy C90259 NICHD Pediatric Terminology C C92945 Ovarian Pregnancy Ovarian Pregnancy An ectopic pregnancy of unknown etiology that occurs in the ovary instead of the uterine corpus. It may result in severe intra-abdominal bleeding. C34945 Ectopic Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92946 Tubal Pregnancy Tubal Pregnancy An ectopic pregnancy that occurs in the fallopian tube instead of the uterine corpus. Causes include pelvic inflammatory disease and prior pelvic surgery. It may result in severe abdominal pain, vaginal bleeding, and tubal rupture. C34945 Ectopic Pregnancy C90259 NICHD Pediatric Terminology C C92946 Tubal Pregnancy Tubal Pregnancy An ectopic pregnancy that occurs in the fallopian tube instead of the uterine corpus. Causes include pelvic inflammatory disease and prior pelvic surgery. It may result in severe abdominal pain, vaginal bleeding, and tubal rupture. C34945 Ectopic Pregnancy C92712 NICHD Pregnancy & Childbirth Terminology C C92947 Rh Immune Globulin Administration Rh Immune Globulin Administration Rho(D) Immune Globulin Administration The administration of Rh Immune Globulin to a pregnant mother to ameliorate the effects of conflicting Rh factors during pregnancy. C15843 Preventive Intervention C90259 NICHD Pediatric Terminology C C92947 Rh Immune Globulin Administration Rh Immune Globulin Administration Rho(D) Immune Globulin Administration The administration of Rh Immune Globulin to a pregnant mother to ameliorate the effects of conflicting Rh factors during pregnancy. C15843 Preventive Intervention C92712 NICHD Pregnancy & Childbirth Terminology C C92949 Pregnancy Test Pregnancy Test Any examination performed to assess if a female is gravid. C18020 Diagnostic Procedure C90259 NICHD Pediatric Terminology C C92949 Pregnancy Test Pregnancy Test Any examination performed to assess if a female is gravid. C18020 Diagnostic Procedure C92712 NICHD Pregnancy & Childbirth Terminology C C94835 Normal Spontaneous Vaginal Delivery Normal Spontaneous Vaginal Delivery Normal Delivery A process of birthing whereby the fetus is born unaided by medical inducements or surgical intervention and without complication. C81303 Vaginal Delivery C89506 NICHD Newborn Screening Terminology C C94835 Normal Spontaneous Vaginal Delivery Normal Spontaneous Vaginal Delivery Normal Delivery A process of birthing whereby the fetus is born unaided by medical inducements or surgical intervention and without complication. C81303 Vaginal Delivery C90259 NICHD Pediatric Terminology C C94835 Normal Spontaneous Vaginal Delivery Normal Spontaneous Vaginal Delivery Normal Delivery A process of birthing whereby the fetus is born unaided by medical inducements or surgical intervention and without complication. C81303 Vaginal Delivery C92712 NICHD Pregnancy & Childbirth Terminology