October 2018 MED-RT (version name 2018.10.01) The Medication Reference Terminology (MED-RT) is the evolutionary successor to the Veterans Health Administration National Drug File – Reference Terminology (VHA NDF-RT™). Both are formal ontological representations of medication terminology, pharmacologic classifications, and asserted authoritative relationships between them. Content in this version of MED-RT represents revisions based on data in the following sources: FDA SPL (2018.06.05) RxNorm (2018.09.04.18AA) MeSH (2018_2018.07.01) SNOMED CT US Edition (2018.09.18AA) UMLS Metathesaurus (2018AA) TOTAL CONCEPTS IN PREVIOUS VERSION (2018.09.04): 3286 TOTAL CONCEPTS IN CURRENT VERSION (2018.10.01): 3322 EPC concepts: 634 MoA concepts: 641 PE concepts: 1868 PK concepts: 59 TC concepts: 66 EXT concepts: 24 HC concepts: 30 There were 36 new concepts manually added for this release to the Therapeutic Categories hierarchy. This release also includes new relationships added by MED-RT SMEs for the following relationship types: CI_ChemClass CI_MoA CI_PE CI_with has_MoA has_PE has_TC may_prevent may_treat ------------------------------------------------------------------------------------------ August/September 2018 MED-RT (version name 2018.09.04) The Medication Reference Terminology (MED-RT) is the evolutionary successor to the Veterans Health Administration National Drug File – Reference Terminology (VHA NDF-RT™). Both are formal ontological representations of medication terminology, pharmacologic classifications, and asserted authoritative relationships between them. Content in this version of MED-RT represents revisions based on data in the following sources: FDA SPL (2018.06.05) RxNorm (2018.08.06.18AA) MeSH (2018_2018.07.01) SNOMED CT US Edition (2018.03.17AB) UMLS Metathesaurus (2018AA) TOTAL CONCEPTS IN PREVIOUS VERSION (2018.07.02): 3286 TOTAL CONCEPTS IN CURRENT VERSION (2018.09.04): 3286 EPC concepts: 634 MoA concepts: 641 PE concepts: 1868 PK concepts: 59 TC concepts: 30 EXT concepts: 24 HC concepts: 30 ------------------------------------------------------------------------------------------ July 2018 MED-RT (version name 2018.07.02) The Medication Reference Terminology (MED-RT) is the evolutionary successor to the Veterans Health Administration National Drug File – Reference Terminology (VHA NDF-RT™). Both are formal ontological representations of medication terminology, pharmacologic classifications, and asserted authoritative relationships between them. Content in this version of MED-RT represents revisions based on data in the following sources: FDA SPL (2018.06.05) RxNorm (2018.06.04.18AA) MeSH (2018_2018.01.01) SNOMED CT US Edition (2018.03.17AB) UMLS Metathesaurus (2017AB) TOTAL CONCEPTS IN PREVIOUS VERSION (2018.06.04): 3282 TOTAL CONCEPTS IN CURRENT VERSION (2018.07.02): 3286 EPC concepts: 634 MoA concepts: 641 PE concepts: 1868 PK concepts: 59 TC concepts: 30 EXT concepts: 24 HC concepts: 30 There were 4 new concepts manually added for this release including 2 added to Established Pharmacologic Classes and 2 added to the Mechanism of Action hierarchy. ------------------------------------------------------------------------------------------ June 2018 MED-RT (version name 2018.06.04) The Medication Reference Terminology (MED-RT) is the evolutionary successor to the Veterans Health Administration National Drug File – Reference Terminology (VHA NDF-RT™). Both are formal ontological representations of medication terminology, pharmacologic classifications, and asserted authoritative relationships between them. Content in this version of MED-RT represents revisions based on data in the following sources: RxNorm (2018.05.07.18AA) MeSH (2018_2018.01.01) SNOMED CT US Edition (2018.03.17AB) UMLS Metathesaurus (2017AB) TOTAL CONCEPTS IN PREVIOUS VERSION (2018.05.07): 3282 TOTAL CONCEPTS IN CURRENT VERSION (2018.06.04): 3282 EPC concepts: 632 MoA concepts: 639 PE concepts: 1868 PK concepts: 59 TC concepts: 30 EXT concepts: 24 HC concepts: 30 A new authority with a value of 'NLMUMLS' was added to this release to support relationships from RxNorm ingredients to MeSH structural classes as defined by the UMLS Metathesaurus. ------------------------------------------------------------------------------------------ May 2018 MED-RT (version name 2018.05.07) The Medication Reference Terminology (MED-RT) is the evolutionary successor to the Veterans Health Administration National Drug File – Reference Terminology (VHA NDF-RT™). Both are formal ontological representations of medication terminology, pharmacologic classifications, and asserted authoritative relationships between them. Content in this version of MED-RT represents revisions based on data in the following sources and updated using the FDA SPL file dated 3/16/18: RxNorm (2018.04.02.17AB) MeSH (2018_2018.01.01) SNOMED CT US Edition (2018.03.17AB) TOTAL CONCEPTS IN PREVIOUS VERSION (2018.04.02): 3277 TOTAL CONCEPTS IN CURRENT VERSION (2018.05.07): 3282 EPC concepts: 632 MoA concepts: 639 PE concepts: 1868 PK concepts: 59 TC concepts: 30 EXT concepts: 24 HC concepts: 30 There were 5 new concepts manually added for this release including 3 added to Established Pharmacologic Classes and 2 added to the Mechanism of Action hierarchy. The following relationship names have been changed in this release: has_Ingredient -> Synonym Of has_Chemical_Structure -> has_SC has_SNOMED_parent -> Child Of has_SNOMED_child -> Parent Of has_SNOMED_synonym -> Synonym Of Please see the full MED-RT documentation for additional relationship information. ------------------------------------------------------------------------------------------ April 2018 MED-RT (version name 2018.04.02) The Medication Reference Terminology (MED-RT) is the evolutionary successor to the Veterans Health Administration National Drug File – Reference Terminology (VHA NDF-RT™). Both are formal ontological representations of medication terminology, pharmacologic classifications, and asserted authoritative relationships between them. Content in this version of MED-RT represents revisions based on data in the following sources and updated using the FDA SPL file dated 3/14/18: RxNorm (2018.03.05.17AB) MeSH (2018_2018.01.01) SNOMED CT US Edition (2017.09.17AA) TOTAL CONCEPTS IN PREVIOUS VERSION (2018.03.05): 3267 TOTAL CONCEPTS IN CURRENT VERSION (2018.04.02): 3277 EPC concepts: 629 MoA concepts: 637 PE concepts: 1868 PK concepts: 59 TC concepts: 30 EXT concepts: 24 HC concepts: 30 There were 10 new concepts manually added for this release including 2 added to Established Pharmacologic Classes, 6 added to the Mechanism of Action hierarchy, and 2 added to the Physiological Effects hierarchy. ------------------------------------------------------------------------------------------ March 2018 MED-RT (version name 2018.03.05) The Medication Reference Terminology (MED-RT) is the evolutionary successor to the Veterans Health Administration National Drug File – Reference Terminology (VHA NDF-RT™). Both are formal ontological representations of medication terminology, pharmacologic classifications, and asserted authoritative relationships between them. Distribution of MED-RT is through the same channels on the same monthly schedule as its predecessor NDF-RT, in XML and other formats. Content in this version of MED-RT represents revisions based on data in the following sources and updated using the FDA SPL file dated 2/5/18: NDF-RT (2018.02.05.17AB) RxNorm (2018.02.05.17AB) MeSH (2017_2017.09.19) SNOMED CT US Edition (2017.09.17AA) TOTAL CONCEPTS IN CURRENT VERSION (2018.03.05): 3267 EPC concepts: 627 MoA concepts: 631 PE concepts: 1866 PK concepts: 59 TC concepts: 30 EXT concepts: 24 HC concepts: 30 There were 5 new concepts manually added for this release including 2 added to Established Pharmacologic Classes and 3 added to the Mechanism of Action hierarchy.