Subset Code Subset Preferred Term Concept Code NCIt Preferred Term NCIt Definition ICDC Preferred Term ICDC Synonym CDISC Preferred Term C166372 Canine Glioma Project Property Terminology C167283 Adjusted Coding Mutation Rate Per Megabase The frequency that coding region mutations occur in a sample per megabase of DNA sequence adjusted for the baseline mutation rate. Adjusted_coding_mutation_rate_per_megabase Adjusted coding mutation rate per megabase C166372 Canine Glioma Project Property Terminology C13717 Anatomic Site Named locations of or within the body. Anatomical_Location Anatomical Location CDISC C166372 Canine Glioma Project Property Terminology C9478 Atypia The condition of being irregular or not conforming to type. Atypia (Y/N) C166372 Canine Glioma Project Property Terminology C167281 Dog Age in Years "The length of a dog's life, stated in years since birth." Dog_Age_years Dog Age years C166372 Canine Glioma Project Property Terminology C167279 Original Dog Breed Data The original text for the dog breed name in the initial documentation. Dog_Breed_Orig Dog Breed Orig C166372 Canine Glioma Project Property Terminology C101295 Whole Exome Sequencing A procedure that can determine the DNA sequence for all of the exons in an individual. Exome WHOLE EXOME SEQUENCING C166372 Canine Glioma Project Property Terminology C42077 Cellular Infiltrate A morphological finding where an influx of cells is detected in locations or numbers that those cells are not normally found. Infiltration (N/F/D) INFILTRATE C166372 Canine Glioma Project Property Terminology C41455 Microvascular Proliferation "A morphological finding indicating the presence of newly formed blood vessels comprised of smooth muscle cells, pericytes and hyperplastic endothelial cells." MVP (Y/N) C166372 Canine Glioma Project Property Terminology C92469 Matched Tissues "Tissues samples from a single source that differ minimally (e.g., normal and cancerous tissues, treated and untreated tissues)." Matched_Normal Matched Normal C166372 Canine Glioma Project Property Terminology C167287 DNA Methylation-Dependent Predicted Disease Class A genetic finding that predicts the disease type based on the DNA methylation profile of the sample. Methylation_Predicted_Class Methylation Predicted Class C166372 Canine Glioma Project Property Terminology C167288 DNA Methylation-Dependent Predicted Disease Class Probability An estimate of the likelihood that the DNA methylation-based disease class prediction is accurate. Methylation_Prediction_Probability Methylation Prediction Probability C166372 Canine Glioma Project Property Terminology C35959 Mitotic Activity Having to do with the presence of dividing (proliferating) cells. Cancerous tissue generally has more mitotic activity than normal tissues. Mitosis (Y/N) C166372 Canine Glioma Project Property Terminology C35867 Morphologic Finding A light microscopic finding that describes the cellular characteristics and architectural patterns of cell populations in a tissue sample. Morphology (A/O/U) C166372 Canine Glioma Project Property Terminology C36184 Necrotic Change A finding indicating the presence of cellular necrosis in a tissue specimen. Necrosis (Y/N) C166372 Canine Glioma Project Property Terminology C124261 Whole Transcriptome Sequencing A procedure that can determine the nucleotide sequence for all of the RNA transcripts in an individual. RNAseq WHOLE TRANSCRIPTOME SEQUENCING C166372 Canine Glioma Project Property Terminology C167284 Reduced-Representation Bisulfite Sequencing A bisulfite-based sequencing techinque where genomic DNA is exposed to one or more restriction enzymes prior to sequencing to produce sequence-specific fragmentation. RRBS C166372 Canine Glioma Project Property Terminology C166393 Specimen Identifier A unique alphanumeric identifier assigned to a specimen. Sample_ID C166372 Canine Glioma Project Property Terminology C167280 Anatomic Site of Origin for Matched Normal Tissue The anatomic site from which a matched normal tissue sample was procured. Source_Matched_Normal_Tissue Source Matched Normal Tissue C166372 Canine Glioma Project Property Terminology C83083 Subject Identifier "A sequence of characters used to identify, name, or characterize a trial or study subject." Subject_ID Subject ID SUBJID C166372 Canine Glioma Project Property Terminology C103264 Tissue Source Site A clinical site that collects and provides patient samples and clinical metadata for research use. TSS C166372 Canine Glioma Project Property Terminology C156419 Days between Diagnosis and Death "The time interval from a person's date of death to the date of initial pathologic diagnosis, represented as a calculated number of days." Time from diagnosis to decease (if known) C166372 Canine Glioma Project Property Terminology C64262 Biologic Sample Preservation Procedure "Procedures utilized to save organic substances from decay. Some preservation procedures are meant to maintain cells, tissues, or organisms in a viable state." Tissue_Archival Tissue Archival C166372 Canine Glioma Project Property Terminology C49236 Therapeutic Procedure An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process. Treatment C166372 Canine Glioma Project Property Terminology C18000 Histologic Grade "The degree of abnormality of cancer cells, a measure of differentiation, the extent to which cancer cells are similar in appearance and function to healthy cells of the same tissue type. The degree of differentiation often relates to the clinical behavior of the particular tumor. Based on the microscopic findings, tumor grade is commonly described by one of four degrees of severity. Histopathologic grade of a tumor may be used to plan treatment and estimate the future course, outcome, and overall prognosis of disease. Certain types of cancers, such as soft tissue sarcoma, primary brain tumors, lymphomas, and breast have special grading systems." Tumor_Grade Grade (high/low) || Tumor Grade C166372 Canine Glioma Project Property Terminology C4741 A classification system grouping neoplasms according to their cellular characteristics. Tumor_Morphology Tumor Morphology C166372 Canine Glioma Project Property Terminology C127771 Tumor Cell to Total Cell Ratio Measurement The determination of the ratio of tumor cells compared to total cells present in a sample. The measurement may be expressed as a ratio or percentage. Tumor_Purity Tumor Purity TUMCECE || Tumor Cells/Total Cells C166372 Canine Glioma Project Property Terminology C101294 Whole Genome Sequencing A procedure that can determine the DNA sequence for nearly the entire genome of an individual. WGS WHOLE GENOME SEQUENCING C166372 Canine Glioma Project Property Terminology C167289 Comparative Brain Tumor Consortium Annotation Present A question regarding whether any annotations were made by a member of the NCI Comparative Brain Tumor Consortium (CBTC). cbtc_annot_present cbtc annot present C166372 Canine Glioma Project Property Terminology C167290 Comments from CBTC Review "A textual explanation, observation, suggestion or question added by the NCI Comparative Brain Tumor Consortium (CBTC) reviewer." comments_cbtc_review comments cbtc review C166372 Canine Glioma Project Property Terminology C162690 Slide ID Examined by Pathologist The identifier for an slide that has been examined by a pathologist. hpe_slide_id hpe slide id C166372 Canine Glioma Project Property Terminology C167285 Mean Exome Read Depth The mean number of times each gene encoding an RNA transcript was fully sequenced. mean_exome_coverage mean exome coverage C166372 Canine Glioma Project Property Terminology C167286 Percent Exome Covered at Read Depth of 30X A measurement of the percent of the exome sequenced at a read depth of 30X. percent_exome_covered_at_30X percent exome covered at 30X C166373 ICDC Property Terminology C78541 Adverse Event Verbatim Description The verbatim description of the adverse event. adverse_event_description adverse event description AETERM C166373 ICDC Property Terminology C166200 Adverse Event Severity Grade A numeric value corresponding to the degree of severity of an adverse event. adverse_event_grade adverse event grade C166373 ICDC Property Terminology C164318 Adverse Event Grade Description A textual description of the grade of an adverse event. adverse_event_grade_description adverse event grade description C166373 ICDC Property Terminology C164320 Adverse Event Term "A term that refers to an adverse event, often taken from a list of standardized terms." adverse_event_term adverse event term C166373 ICDC Property Terminology C164321 Adverse Event Agent Name The name of a therapeutic agent considered to be causally linked to an adverse event. ae_agent_name ae agent name C166373 ICDC Property Terminology C164319 Adverse Event Dose The dose of a therapeutic agent considered to be causally linked to an adverse event. ae_dose ae dose C166373 ICDC Property Terminology C168623 Specify Other Adverse Event A directive to identify the cause of an adverse event when the listed responses are not applicable. ae_other ae other C166373 ICDC Property Terminology C164322 Drug Name The identifier or name of a therapeutic agent. agent_name agent name C166373 ICDC Property Terminology C166199 Agent Unit of Measure The unit of measure that is associated with an agent for administration. agent_units_of_measure agent units of measure C166373 ICDC Property Terminology C166205 Area of Analysis The total area of a sample that is used for analysis. analysis_area analysis area C166373 ICDC Property Terminology C166201 Percent of Glass in Analysis Area The area of a sample on a slide that is represented by glass; the area of the sample that represents gaps in the sample. analysis_area_percentage_glass analysis area percentage glass C166373 ICDC Property Terminology C166202 Percent Pigmented Tumor in Analysis Area "The area of a sample on a slide that is represented by pigmented tumor tissue, which will be analyzed." analysis_area_percentage_pigmented_tumor analysis area percentage pigmented tumor C166373 ICDC Property Terminology C166203 Percent Stroma in Analysis Area The percentage of the analysis area that is represented by stromal tissue. analysis_area_percentage_stroma analysis area percentage stroma C166373 ICDC Property Terminology C166204 Percent Tumor in Analysis Area The percentage of the analysis area that is represented by tumor tissue. analysis_area_percentage_tumor analysis area percentage tumor C166373 ICDC Property Terminology C164323 Surgical Site The anatomical site on which surgery was performed. anatomical_site_of_surgery anatomical site of surgery C166373 ICDC Property Terminology C49236 Therapeutic Procedure An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process. any_therapy any therapy C166373 ICDC Property Terminology C142701 Study Branch A planned point in time within the study design in which there is a subdivision of subjects to particular procedures or treatment groups. arm C166373 ICDC Property Terminology C93728 Arm Description The textual representation of the arm. This is a description of the pathway followed by all subjects in a particular treatment regimen. arm_description arm description Study Arm Description C166373 ICDC Property Terminology C81297 Point in Time Test Given "The hour, minute, and/or second that an examination was administered." assessment_timepoint assessment timepoint C166373 ICDC Property Terminology C166260 Adverse Event Attributed to Commercial Product An indication that an adverse event is causally related to the use of a commercially available product. attribution_to_commercial attribution to commercial C166373 ICDC Property Terminology C166261 Adverse Event Attributed to Disease An indication that an adverse event is causally related to the natural history of disease. attribution_to_disease attribution to disease C166373 ICDC Property Terminology C166262 Adverse Event Attributed to Investigational New Drug An indication that an adverse event is causally related to the use of an investigational new drug (IND). attribution_to_ind attribution to ind C166373 ICDC Property Terminology C166263 Adverse Event Attributed to Other Cause An indication that an adverse event is causally related to an entity that is a not a disease- or research-related process nor a commercial product or investigational new drug (IND). attribution_to_other attribution to other C166373 ICDC Property Terminology C166264 Adverse Event Attributed to Research An indication that an adverse event is causally related to processes a subject was exposed to during a research study. attribution_to_research attribution to research C166373 ICDC Property Terminology C168625 Best Overall Response Registered from Start of Therapy to a Time Point of Interest The most clinically favorable response recorded from the start of the treatment until a specified time point in a study. best_resp_vet_tx_tp_best_response C166373 ICDC Property Terminology C168626 Best Secondary Endpoint Response Registered from Start of Therapy to a Time Point of Interest The most favorable response measured for a secondary endpoint recorded from the start of the treatment until a specified time point in a study. best_resp_vet_tx_tp_secondary_response C166373 ICDC Property Terminology C94536 Best Overall Response The most clinically favorable response recorded from the start of the study treatment until the end of treatment. best_response best response BESTRESP || Best Overall Response C166373 ICDC Property Terminology C25157 Body Surface Area "A measure of the 2-dimensional extent of the body surface (i.e., the skin). Body surface area (BSA) can be calculated by mathematical formula or from a chart that relates height to weight. BSA is often an important factor in dosing." body_surface_area body surface area BSA || Body Surface Area C166373 ICDC Property Terminology C12919 Organ System "An anatomical structure that consists of organs and organ subclasses responsible for certain body functions. Representative examples are the gastrointestinal system, urinary system, and hematopoietic system." body_system body system C166373 ICDC Property Terminology C25206 Temperature "A measure of the average kinetic energy of a system of particles. Temperature may be quantified, in the context of thermodynamics, as the potential of one system to transfer thermal energy to another system until both systems reach a state of thermal equilibrium." body_temperature body temperature TEMP || TEMP || TEMP || TEMP || TEMP || Temperature || Temperature || Temperature || Temperature || Temperature C166373 ICDC Property Terminology C53693 Dog Breed A type of dog known for its special or distinctive characteristics. breed C166373 ICDC Property Terminology C164324 Case Identifier A unique alphanumeric identifier assigned to a specific case. case_id case id C166373 ICDC Property Terminology C142704 Study Description "Specific, essential aspects of an investigation that are detailed, including structure, blinding, dosage, and participant demographics." clinical_study_description clinical study description C166373 ICDC Property Terminology C168630 ICDC Study Identifier A unique alphanumeric code assigned to a project by the Integrated Canine Data Commons (ICDC) that includes an abbreviation representing the project's sponsor organization. clinical_study_designation clinical study designation C166373 ICDC Property Terminology C83082 Study Identifier "A sequence of characters used to identify, name, or characterize the study." clinical_study_id clinical study id STUDYID C166373 ICDC Property Terminology C68631 Study Name The name applied to a scientific investigation. clinical_study_name clinical study name C166373 ICDC Property Terminology C142175 Study Type The nature of the investigation or the investigational use for which clinical study is being done. clinical_study_type clinical study type STYPE || Study Type || Study Type C166373 ICDC Property Terminology C166209 Cohort Description The description of the characteristics that define a cohort. cohort_description cohort description C166373 ICDC Property Terminology C166210 Cohort Dose The dose of medication administered to a particular cohort. cohort_dose cohort dose C166373 ICDC Property Terminology C25393 Comment "A written explanation, observation or criticism added to textual material." comment C166373 ICDC Property Terminology C161320 Comorbid Condition Medical or health condition that is concomitant or concurrent with the primary condition or disease under study. concurrent_disease concurrent disease Comorbid Condition C166373 ICDC Property Terminology C164326 Concurrent Disease Type The classification and naming of comorbid conditions. concurrent_disease_type concurrent disease type C166373 ICDC Property Terminology C166228 Follow-Up Type of Contact A description of the type of interaction that occurs between provider and subject during the follow-up period. contact_type contact type C166373 ICDC Property Terminology C164327 Case Report Form Identifier A unique alphanumeric identifier assigned to a specific case report form. crf_id crf id C166373 ICDC Property Terminology C165236 Treatment Assignment Code An identification code assigned to each unique treatment regimen to uniformly group patients for separate analysis of adverse events and response data. ctep_treatment_assignment_code ctep treatment assignment code C166373 ICDC Property Terminology C166208 Chemotherapeutic Cycle Number The number of the individual chemotherapeutic cycle. cycle_number cycle number C166373 ICDC Property Terminology C156819 Date of Last Administration The date of the last administration of the substance of interest. date_last_medication_administration date last medication administration C166373 ICDC Property Terminology C166218 Date of Best Response The date on which the best response to therapy was observed and recorded. date_of_best_response date of best response C166373 ICDC Property Terminology C94173 Biologic Entity Birth Date The date (and time) on which the biologic entity is born. date_of_birth date of birth C166373 ICDC Property Terminology C166206 Chemotherapeutic Cycle End Date The date on which a chemotherapeutic cycle is ended. date_of_cycle_end date of cycle end C166373 ICDC Property Terminology C166207 Chemotherapeutic Cycle Start Date The date on which a chemotherapeutic cycle is started. date_of_cycle_start date of cycle start C166373 ICDC Property Terminology C164339 Date of Diagnosis The date on which a diagnosis of disease was made. date_of_diagnosis date of diagnosis C166373 ICDC Property Terminology C166219 Date of Disease Progression The date on which disease progression was observed and recorded. date_of_disease_progression date of disease progression C166373 ICDC Property Terminology C164340 Date of Evaluation The date on which an evaluation was performed. date_of_evaluation date of evaluation C166373 ICDC Property Terminology C83030 Physical Examination Date The date that the physical examination occurred on. date_of_examination date of examination PEDAT C166373 ICDC Property Terminology C164328 Date of First Dose The date on which the first dose of a specified treatment regiment was administered. date_of_first_dose date of first dose C166373 ICDC Property Terminology C166265 Histologic Confirmation Date The date that a histological diagnosis was confirmed. date_of_histology_confirmation date of histology confirmation C166373 ICDC Property Terminology C166266 Institutional Animal Care and Use Committee Approval Date The date that the Institutional Animal Care and Use Committee (IACUC) approved an animal study protocol. This date cannot be released to funding agencies until congruency between the animal use in the funding proposal and the IACUC approved protocol has been verified. date_of_iacuc_approval date of iacuc approval C166373 ICDC Property Terminology C93579 Informed Consent Date The date (and time) the patient gives consent to a surgical or medical procedure or participation in a clinical study after achieving an understanding of the relevant medical facts and the risks involved. date_of_informed_consent date of informed consent C166373 ICDC Property Terminology C156916 Date of Last Contact The date of the last contact. date_of_last_contact date of last contact C166373 ICDC Property Terminology C164329 Date of Last Dose The date on which the last dose of a specified treatment regiment was administered. date_of_last_dose date of last dose C166373 ICDC Property Terminology C156814 Date of Last Therapy "The date of the last radiation treatment, chemotherapy, molecular targeted therapy, or immunotherapy treatment." date_of_last_dose_any_therapy date of last dose any therapy C166373 ICDC Property Terminology C164342 Date of Last NSAID Administration The date on which a patient last received an NSAID. date_of_last_dose_nsaid date of last dose nsaid C166373 ICDC Property Terminology C164343 Date of Last Steroid Administration The date on which a patient last received steroid. date_of_last_dose_steroid date of last dose steroid C166373 ICDC Property Terminology C166253 Date of Missed Dose Specifies the date of a missed dose of a therapeutic agent. date_of_missed_dose date of missed dose C166373 ICDC Property Terminology C93681 Study Registration Date The date (and time) the subject has been registered to the study. date_of_registration date of registration C166373 ICDC Property Terminology C81286 Collection Date The date on which the sample or data was collected. date_of_sample_collection date of sample collection C166373 ICDC Property Terminology C159308 Date of Surgical Procedure A question about the date on which a surgical procedure was performed. date_of_surgery date of surgery C166373 ICDC Property Terminology C83032 Vital Signs Date The date on which a vital signs assessment is carried out. date_of_vital_signs date of vital signs VSDAT C166373 ICDC Property Terminology C93610 Off Study Date The date (and time) when the study subject is removed from the study. date_off_study date off study C166373 ICDC Property Terminology C166220 Date Off Treatment The date on which a subject is no longer receiving therapy. date_off_treatment date off treatment C166373 ICDC Property Terminology C93718 Adverse Event Resolution Date The date (and time) when the adverse event ends or returns to baseline. date_resolved date resolved C166373 ICDC Property Terminology C166251 Study Conduct Date Range The date range that encompasses the dates that a study was performed. dates_of_conduct dates of conduct C166373 ICDC Property Terminology C166221 Treatment Cycle Day Number A number that indicates the position of a day within a treatment cycle. day_in_cycle day in cycle C166373 ICDC Property Terminology C2991 Disease or Disorder "Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function." disease_term disease term C166373 ICDC Property Terminology C93399 Document Identifier The unique identification of a document in a specified context. document_number document number C166373 ICDC Property Terminology C25488 Dose "A quantity of an agent (such as substance or energy) administered, taken, or absorbed at one time." dose_level dose level DOSE || DOSE || Dose Level || Dose per Administration || TRTDOS C166373 ICDC Property Terminology C123282 Regimen-Limiting Toxicity A side effect of a drug or other treatment that is serious enough to necessitate a dose modification. dose_limiting_toxicity dose limiting toxicity C166373 ICDC Property Terminology C71137 Dose Regimen "A treatment plan that specifies the amount, schedule, and the duration of intervention(s)." dose_schedule dose schedule DOSRGM || DOSRGM || Dose Regimen C166373 ICDC Property Terminology C166259 Dose Unit of Measure The unit of measure that is associated with the dose of a substance administered to the subject. dose_units_of_measure dose units of measure C166373 ICDC Property Terminology C41328 Electrocardiographic Finding Graphic representation and categorization of the electrical vectors produced by the depolarization and repolarization of myocardial tissue. ecg C166373 ICDC Property Terminology C166224 Enrollment Document Number The identifier assigned to an enrollment document. enrollment_document_number enrollment document number C166373 ICDC Property Terminology C166226 Evaluation Code The code assigned to an evaluation. evaluation_code evaluation code C166373 ICDC Property Terminology C166227 Evaluation Sequence Number "The number assigned to an evaluation, indicating where a particular evaluation falls within a sequence of multiple evaluations." evaluation_number evaluation number C166373 ICDC Property Terminology C166267 Unknown Status Reason An explanation of why the status of a subject is unknown. explain_unknown_status explain unknown status C166373 ICDC Property Terminology C171190 Electronic File Description A free text field that can be used to document details about an electronic file that may not be captured elsewhere. file_description file description C166373 ICDC Property Terminology C171252 Electronic File Format The format of an electronic file. file_format file format C166373 ICDC Property Terminology C47922 Pathname "The specification of a node (file or directory) in a hierarchical file system, usually specified by listing the nodes top-down." file_location file location C166373 ICDC Property Terminology C171191 Electronic File Name The literal identifier for an electronic file. file_name file name C166373 ICDC Property Terminology C171192 Electronic File Size The size of an electronic file. file_size file size C166373 ICDC Property Terminology C171193 Electronic File Status The condition for an electronic file relative to the current data or file processing step. file_status file status C166373 ICDC Property Terminology C172272 Electronic File Content Type The nature of the content stored in an electronic file. file_type file type C166373 ICDC Property Terminology C156846 Follow-Up Information Information regarding the follow-up period. follow_up_data follow up data C166373 ICDC Property Terminology C166229 Normal or Tumor Sample Pathology Indicator Specifies whether a sample is derived from normal or tumor-bearing tissue. general_sample_pathology general sample pathology C166373 ICDC Property Terminology C18000 Histologic Grade "The degree of abnormality of cancer cells, a measure of differentiation, the extent to which cancer cells are similar in appearance and function to healthy cells of the same tissue type. The degree of differentiation often relates to the clinical behavior of the particular tumor. Based on the microscopic findings, tumor grade is commonly described by one of four degrees of severity. Histopathologic grade of a tumor may be used to plan treatment and estimate the future course, outcome, and overall prognosis of disease. Certain types of cancers, such as soft tissue sarcoma, primary brain tumors, lymphomas, and breast have special grading systems." histological_grade histological grade || tumor grade || tumor_grade C166373 ICDC Property Terminology C166230 Histopathology-Cytopathology Indicator An indicator denoting whether a diagnosis was assigned based on histopathology or cytopathology. histology_cytopathology histology cytopathology C166373 ICDC Property Terminology C94272 Person Initials "The first letters of the person's first name, middle name, and last name." initials C166373 ICDC Property Terminology C25334 Length "The linear extent in space from one end of something to the other end, or the extent of something from beginning to end." length_of_tumor length of tumor LENGTH || LENGTH || LENGTH || LENGTH || LENGTH || LENGTH || Length || Length || Length || Length || Length || Length C166373 ICDC Property Terminology C166231 Lesion Description "Specifies the description of a localized pathological or traumatic structural change, damage, deformity, or discontinuity of tissue, organ, or body part." lesion_description lesion description C166373 ICDC Property Terminology C93587 Lesion Number "The integer assigned to a localized pathological or traumatic structural change, damage, deformity, or discontinuity of tissue, organ or body part." lesion_number lesion number C166373 ICDC Property Terminology C166232 Lesion Site "Specifies the anatomic site of a localized pathological or traumatic structural change, damage, deformity, or discontinuity of tissue, organ, or body part." lesion_site lesion site C166373 ICDC Property Terminology C96684 Longest Diameter The longest possible length of a straight line passing through the center of a circular or spheroid object that connects two points on the circumference. longest_measurement longest measurement LDIAM || LDIAM || LDIAM || LDIAM || Longest Diameter || Longest Diameter || Longest Diameter || Longest Diameter C166373 ICDC Property Terminology C171276 MD5 Checksum A 32-character hexadecimal number that is computed on a file. md5sum C166373 ICDC Property Terminology C167209 Measurable Lesion A finding indicating that a localized pathological lesion can be measured in at least one dimension. measurable_lesion measurable lesion C166373 ICDC Property Terminology C166268 How was the Extent of Disease Measured A question pertaining to how the extent of a disease or lesion was measured. measured_how measured how C166373 ICDC Property Terminology C459 Medication "A drug product that contains one or more active and/or inactive ingredients; it is intended to treat, prevent or alleviate the symptoms of disease. This term does not refer to the individual ingredients that make up the product." medication C166373 ICDC Property Terminology C167190 Dose Administered A quantity of an agent given to an individual at one time. medication_actual_dose medication actual dose C166373 ICDC Property Terminology C166233 Medication Acutal Unit of Measure The actual unit of measure used to quantify an administered dose of a therapeutic agent to a subject. medication_actual_units_of_measure medication actual units of measure C166373 ICDC Property Terminology C166235 Medication Course Number "The number assigned to a course of therapeutic agent administration, indicating where a particular course of treatment falls within a sequence of treatments." medication_course_number medication course number C166373 ICDC Property Terminology C83168 Duration of Use The amount of time that a thing is consumed or employed. medication_duration medication duration CDUR C166373 ICDC Property Terminology C70848 Lot Number A distinctive alpha-numeric identification code assigned by the manufacturer or distributor to a specific quantity of manufactured material or product within a batch. medication_lot_number medication lot number LOT || LOT || Lot Number C166373 ICDC Property Terminology C166269 Missed Medication Dose Name The name of the medication that was not taken when a dose was missed. medication_missed_dose medication missed dose C166373 ICDC Property Terminology C25709 Unit of Measure "A named quantity in terms of which other quantities are measured or specified, used as a standard measurement of like kinds." medication_units_of_measure medication units of measure C166373 ICDC Property Terminology C166236 Medication Vial Identifier An identifier associated with a particular vial of medication. medication_vial_id medication vial id C166373 ICDC Property Terminology C50429 Missed Dose A dose of medicine that was not taken at the prescribed dosing interval. missed_dose_amount missed dose amount C166373 ICDC Property Terminology C166234 Missed Dose Unit of Measure The unit of measure used to quantify a missed dose of a therapeutic agent to a subject. missed_dose_units_of_measure missed dose units of measure C166373 ICDC Property Terminology C164330 Modified ECOG Performance Status A version of the ECOG performance status scale for use in canines. modified_ecog modified ecog C166373 ICDC Property Terminology C166270 Necropsy Sample A biospecimen collected during the surgical examination of a dead body. necropsy_sample necropsy sample C166373 ICDC Property Terminology C158349 Neutered Indicator An indication as to whether the animal(s) has been neutered. neutered_indicator neutered indicator NEUTIND || Neutered Indicator C166373 ICDC Property Terminology C166238 Non-Tumor Tissue Area The area within a sample that is represented by non-tumor tissue. non_tumor_tissue_area non tumor tissue area C166373 ICDC Property Terminology C166271 Non-responsive Therapy Type The categorization of the treatment that was administered to a subject that did not produce the intended (therapeutic) effect. nonresponse_therapy_type nonresponse therapy type C166373 ICDC Property Terminology C166241 Number of Prior Regimens A number that identifies the number of prior cyles of any therapy a subject has received. number_of_prior_regimens_any_therapy number of prior regimens any therapy C166373 ICDC Property Terminology C166242 Number of Prior Regimens of NSAID A number that identifies the number of prior cyles of NSAID therapy a subject has received. number_of_prior_regimens_nsaid number of prior regimens nsaid C166373 ICDC Property Terminology C166243 Number of Prior Regimens of Steroids A number that identifies the number of prior cyles of steroid therapy a subject has received. number_of_prior_regimens_steroid number of prior regimens steroid C166373 ICDC Property Terminology C28277 Pathology Report "A report that provides a description of the gross and microscopic examination of the specimen and is used to make a diagnosis and to determine treatment. It defines which structures and organs of the body are involved by the tumor, verifies the primary site of the cancer and describes the extent to which it has spread." pathology_report pathology report C166373 ICDC Property Terminology C164338 Age of Enrollment "The age of a subject when entering a group, catalog, list, or study." patient_age_at_enrollment patient age at enrollment C166373 ICDC Property Terminology C69257 Subject Name The name of the individual of interest. patient_first_name patient first name C166373 ICDC Property Terminology C164337 Patient Identifier An alphanumeric identifier assigned to a specific patient. patient_id patient id C166373 ICDC Property Terminology C166244 Patient Status An indicator that provides information on the current health status of a patient. patient_status patient status C166373 ICDC Property Terminology C70730 Clinical Study Population Subgroup "Relatively uniform groups (e.g. etiologically and pathogenetically more homogeneous, racial, ethnic, or gender-specific, or the disease- or condition-specific) of study subjects formed within a clinical study population for a separate analysis. The selection of the subgroups, methods of subgroup analysis, and anticipated difference in observation outcome(s) have to be defined and justified in the study protocol and based on known biological mechanisms, and/or findings in previous studies." patient_subgroup patient subgroup C166373 ICDC Property Terminology C81328 Body Weight The weight of a subject. patient_weight patient weight || weight BW || Body Weight C166373 ICDC Property Terminology C166247 Physical Examination Comment A field for use to add comments regarding a physical examination. pe_comment pe comment C166373 ICDC Property Terminology C83119 Physical Exam Result The outcome of the physical examination assessment. pe_finding pe finding PERES C166373 ICDC Property Terminology C166245 Percent Stromal Tissue The percentage of stromal tissue in a sample. percentage_stroma percentage stroma C166373 ICDC Property Terminology C166246 Percent Tumor Tissue The percentage of tumor tissue in a sample. percentage_tumor percentage tumor C166373 ICDC Property Terminology C25257 Phase "A distinguishable part, a stage in a series of events or in a process of development, e.g. any of the varying aspects or stages in course of a disease; a fraction of a cycle." phase C166373 ICDC Property Terminology C166254 Change Since Last Physical Exam Changes from the previous physical examination that are noted during the current physical examination. physical_exam_changes physical exam changes C166373 ICDC Property Terminology C113376 Physical Exam Performed An indication or description that a subject physical examination test has occurred. physical_exam_performed physical exam performed PEPERF C166373 ICDC Property Terminology C70713 Biospecimen Type "The type of a material sample taken from a biological entity for testing, diagnostic, propagation, treatment or research purposes. This includes particular types of cellular molecules, cells, tissues, organs, body fluids, embryos, and body excretory substances." physical_sample_type physical sample type SPEC C166373 ICDC Property Terminology C40974 First Name A word or group of words indicating a person's first (personal or given) name; the name that precedes the surname. pi_first_name pi first name C166373 ICDC Property Terminology C40975 Last Name A word or group of words indicating a person's last (family) name. pi_last_name pi last name C166373 ICDC Property Terminology C166237 Middle Initial The first letter of a person's middle name. pi_middle_initial pi middle initial C166373 ICDC Property Terminology C15477 Prior Radiation Therapy An indicator that a person previously received radiation treatment for the same condition. previously_irradiated previously irradiated C166373 ICDC Property Terminology C16124 Prior Therapy Prior action or administration of therapeutic agents that produced an effect that is intended to alter or stop a pathologic process. previously_treated previously treated C166373 ICDC Property Terminology C158874 Primary Site of Disease The primary site of a disease of interest. primary_disease_site primary disease site C166373 ICDC Property Terminology C166248 Prior NSAID Exposure Indicator Specifies wheter a subject has had prior exposure to NSAID. prior_nsaid_exposure prior nsaid exposure C166373 ICDC Property Terminology C166249 Prior Steroid Exposure Indicator Specifies wheter a subject has had prior exposure to steroids. prior_steroid_exposure prior steroid exposure C166373 ICDC Property Terminology C166250 Prior Therapy Type Specifies the type of prior therapy. prior_therapy_type prior therapy type C166373 ICDC Property Terminology C25218 Intervention or Procedure "An activity that produces an effect, or that is intended to alter the course of a disease in a patient or population. This is a general term that encompasses the medical, social, behavioral, and environmental acts that can have preventive, therapeutic, or palliative effects." procedure C166373 ICDC Property Terminology C93495 Acronym The non-unique initials or abbreviated name used for identification. program_acronym program acronym C166373 ICDC Property Terminology C166272 Program External URL A URL address for a research program or study that is accessible by those outside the host institution. program_external_url program external url C166373 ICDC Property Terminology C166273 Program Full Description An unabridged description of a research program or study. program_full_description program full description C166373 ICDC Property Terminology C166274 Program Name The name applied to a research program or study. program_name program name C166373 ICDC Property Terminology C166275 Program Short Description An abbreviated description of a research program or study. program_short_description program short description C166373 ICDC Property Terminology C168629 ICDC Program Sort Order A value assigned by the Integrated Canine Data Commons (ICDC) that indicates where a particular project is located in the list of all of the projects included in ICDC. program_sort_order program sort order C166373 ICDC Property Terminology C25749 Pulse The rhythmic wave within the arteries occurring with each contraction of the left ventricle. pulse C166373 ICDC Property Terminology C38085 Pulse Oximetry A non-invasive method that provides estimates of arterial oxyhemoglobin saturation by utilizing selected wavelengths of light to determine the saturation of oxyhemoglobin. pulse_ox pulse ox PULSE OXIMETRY C166373 ICDC Property Terminology C49627 Reason for Non-Completion The reason that a subject was discontinued from a clinical trial. reason_off_study reason off study C166373 ICDC Property Terminology C166276 Reason Off Treatment The reason the administration of a drug or therapeutic procedure was interrupted or stopped. reason_off_treatment reason off treatment C166373 ICDC Property Terminology C41206 Institution "An established society, corporation, foundation or other organization founded and united for a specific purpose, e.g. for health-related research; also used to refer to a building or buildings occupied or used by such organization." registering_institution registering institution INSTITUTION C166373 ICDC Property Terminology C4809 Residual Disease Tumor cells that remain in the body following cancer treatment. residual_disease residual disease C166373 ICDC Property Terminology C164331 Respiratory Pattern "A description of the breathing cycle at a point in time, which is informed by the rate, depth, and regularity of respiration." respiration_pattern respiration pattern C166373 ICDC Property Terminology C49678 Respiratory Rate "The rate of breathing (inhalation and exhalation) measured within in a unit time, usually expressed as breaths per minute." respiration_rate respiration rate RESP || RESPRATE || Respiratory Rate || Respiratory Rate C166373 ICDC Property Terminology C38114 Route of Administration "Designation of the part of the body through which or into which, or the way in which, the medicinal product is intended to be introduced. In some cases a medicinal product can be intended for more than one route and/or method of administration." route_of_administration route of administration ROUTE || ROUTE || ROUTE || Route of Administration || Route of Administration C166373 ICDC Property Terminology C166393 Specimen Identifier A unique alphanumeric identifier assigned to a specimen. sample_id sample id C166373 ICDC Property Terminology C64262 Biologic Sample Preservation Procedure "Procedures utilized to save organic substances from decay. Some preservation procedures are meant to maintain cells, tissues, or organisms in a viable state." sample_preservation sample preservation C166373 ICDC Property Terminology C171435 Sample Anatomic Site The anatomic site from which a biospecimen was obtained. sample_site sample site C166373 ICDC Property Terminology C28421 Sex The assemblage of physical properties or qualities by which male is distinguished from female; the physical difference between male and female; the distinguishing peculiarity of male or female. sex SEX C166373 ICDC Property Terminology C166277 Short Site Name The abbreviation or abridged identifier representing the place hosting a research program or study. site_short_name site short name C166373 ICDC Property Terminology C171436 Sample Pathology Indicator Specifies the pathologic process or disease associated with a sample. specific_sample_pathology specific sample pathology C166373 ICDC Property Terminology C28108 Disease Stage Qualifier An adjectival term that can specify or describe a disease stage. stage_of_disease stage of disease C166373 ICDC Property Terminology C78441 Start Time The time at which something is to start or did start. start_time start time STTIM C166373 ICDC Property Terminology C82573 End Time The time when an event has ceased. stop_time stop time ENTIM C166373 ICDC Property Terminology C171437 ICDC Summarized Sample Type Indicator "An ICDC property that specifies the combined data that indicates the type (tissue, blood, cells, etc.), normal or tumor origin and derivation from a primary tumor or metastatic lesion for a sample." summarized_sample_type summarized sample type C166373 ICDC Property Terminology C164341 Surgical Finding A finding or observation that is made during surgery. surgical_finding surgical finding C166373 ICDC Property Terminology C25298 Systolic Blood Pressure The maximum pressure exerted into the systemic arterial circulation during the contraction of the left ventricle of the heart. systolic_bp systolic bp SYSBP || SYSBP || Systolic Blood Pressure || Systolic Blood Pressure C166373 ICDC Property Terminology C94520 Target Lesion Identification "The identification of a lesion that is present at baseline, is measurable and is the primary target of the therapeutic intervention." target_lesion target lesion TARGET C166373 ICDC Property Terminology C168631 Therapeutic Indicator An indication as to whether a specified treatment has been administered to a subject. therapeutic_indicator therapeutic indicator C166373 ICDC Property Terminology C157517 Therapy Used at Visit An indication of the type of therapy used during a visit. therapy_type therapy type C166373 ICDC Property Terminology C94394 Cumulative Dose The total amount of a therapeutic agent administered to a subject over a defined period of time. total_dose total dose C166373 ICDC Property Terminology C93620 Period Dose Total Total of all doses of treatment in a given period of time. total_number_of_doses_any_therapy total number of doses any therapy C166373 ICDC Property Terminology C164333 NSAID Total Dose The total number of doses of NSAIDs given in a given period of time. total_number_of_doses_nsaid total number of doses nsaid C166373 ICDC Property Terminology C164334 Steroid Total Dose The total number of doses of steroids given in a given period of time. total_number_of_doses_steroid total number of doses steroid C166373 ICDC Property Terminology C166239 Total Sample Tissue Area The total area of a tissue sample. total_tissue_area total tissue area C166373 ICDC Property Terminology C164335 Treatment Data Data pertaining to the medical or surgical treatment of a patient. treatment_data treatment data C166373 ICDC Property Terminology C171433 Treatment Performed at Study Site Indicator Specifies whether treatment was administered to a subject at a study site. treatment_performed_at_site treatment performed at site C166373 ICDC Property Terminology C171434 Treatment Performed in Minimal Residual Disease Indicator Specifies whether a treatment was administered to a subject that was diagnosed with minimal residual disease. treatment_performed_in_minimal_residual treatment performed in minimal residual C166373 ICDC Property Terminology C157518 Therapy Used Since Last Visit An indication of the type of therapy used since the last visit. treatment_since_last_contact treatment since last contact C166373 ICDC Property Terminology C171438 Tumor Sample Origin Indicator Specifies whether a sample was derived from a primary tumor versus a metastatic lesion. tumor_sample_origin tumor sample origin C166373 ICDC Property Terminology C166240 Tumor Tissue Area The area within a sample that is comprised of tumor tissue. tumor_tissue_area tumor tissue area C166373 ICDC Property Terminology C41334 Unexpected Adverse Event "Any adverse event associated with a medical product or procedure that has not been previously observed, whether or not the event was anticipated because of the pharmacologic properties of the study agent or the nature of the medical procedure. This includes events that are more serious than expected or occur more frequently than expected, particularly, any adverse experience, the nature, severity or frequency of which is not consistent with the product label, or with the current investigator brochure for investigational agent; or with the risk information described in the investigational plan or protocol or consent form." unexpected_adverse_event unexpected adverse event unexpected adverse drug reaction C166373 ICDC Property Terminology C54100 Universally Unique Identifier "A 128 bit identifier. Depending on the mechanism used to generate it, it is either guaranteed to be different from all other UUIDs/GUIDs generated until 3400 AD or extremely likely to be different. Its relatively small size lends itself well to sorting, ordering, and hashing of all sorts, storing in databases, simple allocation, and ease of programming in general." uuid C166373 ICDC Property Terminology C164336 Veterinary Medical Center A veterinary institution that provides medical or surgical care and treatment for the sick or the injured. veterinary_medical_center veterinary medical center C166373 ICDC Property Terminology C83031 Visit Date The date on which a visit occurred. visit_date visit date VISDAT C166373 ICDC Property Terminology C83101 Visit Number The numerical identifier of the visit. visit_number visit number C166373 ICDC Property Terminology C94515 Tumor Volume volume_of_tumor volume of tumor C166373 ICDC Property Terminology C158774 Pathologic Width The longest diameter of a tumor from the pathology examination of a specimen. width_of_tumor width of tumor