A C177536 GDC Property Terminology C170562 Prepared Amount The quantity of a product that has been made ready for use. amount A C177536 GDC Property Terminology C173595 First Variant Gene Symbol The gene symbol that represents either a single gene that has a mutation or the gene that comprises the 5' portion of the coding sequence involved in a fusion gene mutation. gene_symbol gene symbol A C177536 GDC Property Terminology C181350 Number of Sequence Variants A quantitative assessment of the number of sequence variants within a region of interest. loci_abnormal_count loci abnormal count A C177536 GDC Property Terminology C182036 Nucleotide Sequencing Site Name The name of the site that performed nucleotide sequencing on a sample. sequencing_center sequencing center A C177536 GDC Property Terminology C182037 Nucleotide Sequencing Analyte Volume The volume occupied by an analyte that is or will be subjected to nucleotide sequence analysis. analyte_volume analyte volume A C177536 GDC Property Terminology C182038 Nucleotide Sequencing Aliquot Weight The weight of an aliquot that is or will be subjected to nucleotide sequence analysis. aliquot_quantity aliquot quantity A C177536 GDC Property Terminology C182039 Nucleotide Sequencing Analyte Weight The weight of an analyte that is or will be subjected to nucleotide sequence analysis. analyte_quantity analyte quantity A C177536 GDC Property Terminology C182040 Nucleotide Sequencing Date The date that nucleotide sequencing was performed. sequencing_date sequencing date A C177536 GDC Property Terminology C182041 Total Number of Genetic Loci Assayed The total number of genetic loci assayed represented by the number of normal loci plus the number of abnormal loci. loci_count loci count A C177536 GDC Property Terminology C182042 Number of Patient Relatives with History of Cancer The number of patient relatives that have a known history of cancer. relatives_with_cancer_history_count relatives with cancer history count A C177536 GDC Property Terminology C182043 Number of Prostatic Chips Examined The total number of prostatic chips subjected to biomarker analysis. prostatic_chips_total_count prostatic chips total count A C177536 GDC Property Terminology C182044 Number of Prostatic Chips Positive The number of prostatic chips that have a positive biomarker result. prostatic_chips_positive_count prostatic chips positive count A C177536 GDC Property Terminology C182045 Number of Recovered Cells Expected The number of cells one expected to recover during single cell isolation. number_expect_cells number expect cells A C177536 GDC Property Terminology C182046 Number of Years in Occupation The number of years a subject has worked in a specific occupation. occupation_duration_years occupation duration years A C177536 GDC Property Terminology C182047 Number of RECIST Baseline Target Lesion The number of baseline target lesions, as described by the Response Evaluation Criteria in Solid Tumours (RECIST) criteria. recist_targeted_regions_number recist targeted regions number A C177536 GDC Property Terminology C182048 Predicted Maximum Read Length of Sequenced Fragment The predicted maximum length for the nucleotide fragments sequenced during a read. fragment_maximum_length fragment maximum length A C177536 GDC Property Terminology C182049 Predicted Mean Read Length of Sequenced Fragment The predicted mean length for the nucleotide fragments sequenced during a read. fragment_mean_length fragment mean length A C177536 GDC Property Terminology C182050 Predicted Minimum Read Length of Sequenced Fragment The predicted minimum length for the nucleotide fragments sequenced during a read. fragment_minimum_length fragment minimum length A C177536 GDC Property Terminology C182051 Project Data Submission Enabled Indicator An indicator specifying that data may be submitted to a project. submission_enabled submission enabled A C177536 GDC Property Terminology C182052 Project Release Request Indicator An indicator that specifies that a submitter has requested that their project be released. release_requested release requested A C177536 GDC Property Terminology C182053 Project Reviewed by AWG Indicator An indication that the project has been reviewed by the GDC AWG. awg_review awg review A C177536 GDC Property Terminology C182054 Project Submission Status The submission status for a project. state A C177536 GDC Property Terminology C182055 RECIST Baseline Target Lesion Sum The sum of baseline target lesions, as described by the Response Evaluation Criteria in Solid Tumours (RECIST) criteria. recist_targeted_regions_sum recist targeted regions sum A C177536 GDC Property Terminology C182056 Read Group Name The name assigned to a read group. read_group_name read group name A C177536 GDC Property Terminology C182057 Sequencing Adapter Name The name of a nucleic acid sequencing adapter. adapter_name adapter name A C177536 GDC Property Terminology C182058 Sequencing Library Name The name of the nucleotide sequencing library. library_name library name A C177536 GDC Property Terminology C182059 Paired End Reads Indicator An indicator that specifies whether a nucleotide sample was subjected to paired end reads. is_paired_end is paired end A C177536 GDC Property Terminology C182060 Parent with Radiation Exposure Indicator An indicator that specifies if a subject's parent was exposed to radiation. parent_with_radiation_exposure parent with radiation exposure A C177536 GDC Property Terminology C182061 Pathology Report UUID A universally unique identifier assigned to a pathology report. pathology_report_uuid pathology report uuid A C177536 GDC Property Terminology C182062 Year of Initial Cancer Diagnosis The four digit year associated with the receipt of the initial cancer diagnosis. year_of_diagnosis year of diagnosis A C177536 GDC Property Terminology C182063 Year of Pancreatitis Onset The four digit year associated with the receipt of the initial diagnosis of chronic pancreatitis. pancreatitis_onset_year pancreatitis onset year A C177536 GDC Property Terminology C182064 FFPE Indicator An indicator that specifies whether a specimen or sample was subjected to formalin fixation and paraffin embedding (FFPE). is_ffpe is ffpe A C177536 GDC Property Terminology C182065 Trim Adapter Sequence Indicator An indicator specifying whether adapter trimming was suggested. to_trim_adapter_sequence to trim adapter sequence A C177536 GDC Property Terminology C182079 Reported Average Base Quality The average base call quality reported by the system. average_base_quality average base quality A C177536 GDC Property Terminology C182080 Sequencing Adapter Nucleic Acid Sequence The chemical composition of a sequencing adapter, which includes the nucleotide base sequence and any modifying chemical structures. adapter_sequence adapter sequence A C177536 GDC Property Terminology C182081 Sequencing Lane Identifier The numerical identifier for the lane or machine unit where a sample was located during nucleotide sequencing. lane_number lane number A C177536 GDC Property Terminology C182082 Tissue Microassay Array Position Identifier The alphanumeric identifier for the position of a specific tissue sample on a microassay array slide. tissue_microarray_coordinates tissue microarray coordinates A C177536 GDC Property Terminology C182083 Test Site Domain Name The internet domain name or namespace associated with the institute or center that manages a study or project. namespace A C177536 GDC Property Terminology C182084 Sequencing Library Preparation Kit Catalog Number The catalog number for the nucleotide sequencing library kit. library_preparation_kit_catalog_number library preparation kit catalog number A C177536 GDC Property Terminology C182085 Sequencing Library Preparation Kit Name The name for the nucleotide sequencing library kit. library_preparation_kit_name library preparation kit name A C177536 GDC Property Terminology C182086 Sequencing Library Preparation Kit Vendor Name The vendor name for the nucleotide sequencing library kit. library_preparation_kit_vendor library preparation kit vendor A C177536 GDC Property Terminology C182087 Sequencing Library Preparation Kit Version The version for the nucleotide sequencing library kit. library_preparation_kit_version library preparation kit version A C177536 GDC Property Terminology C182088 Slide Section Anatomic Site The anatomic site from which a section mounted to a slide was obtained. section_location section location A C177536 GDC Property Terminology C182089 Source Site Name The name of the center or institution that provided an item. source_center source center A C177536 GDC Property Terminology C182090 Spike-In Concentration The concentration of spike-in standard in a sample or assay. spike_ins_concentration spike ins concentration A C177536 GDC Property Terminology C182091 Spike-In FASTA File Name The name of an electronic file containing FASTA data obtained in the presence of a spiked-in standard. spike_ins_fasta spike ins fasta A C177536 GDC Property Terminology C182092 Spike-In Inclusion Indicator An indication as to whether a spiked-in standard was included in an assay or experiment. includes_spike_ins includes spike ins A C177536 GDC Property Terminology C182093 Standard Deviation for Read Length of Sequenced Fragments The standard deviation for the length of the nucleotide fragments sequenced during a read. fragment_standard_deviation_length fragment standard deviation length A C177536 GDC Property Terminology C182094 Request for Submission Indicator An indicator that specifies that a user has requested that their project or data be submitted to the database. request_submission request submission A C177536 GDC Property Terminology C182095 Submitter Reviewing Project Indicator An indication as to whether a project is being reviewed by the submitter. in_review in review A C177536 GDC Property Terminology C182096 Suspected Reason for Disease Response The suspected reason that a subject had a certain disease response. cause_of_response cause of response A C177536 GDC Property Terminology C182097 Undescended Testis Corrected Indicator An indicator that specifies if a subject's undescended testis was corrected. undescended_testis_corrected undescended testis corrected A C177536 GDC Property Terminology C182099 Undescended Testis History Indicator An indicator that specifies if a subject had an undescended testis. undescended_testis_history undescended testis history A C177536 GDC Property Terminology C182101 Undescended Testis Corrected Method An activity performed to correct undescended testis. undescended_testis_corrected_method undescended testis corrected method A C177536 GDC Property Terminology C182102 Undescended Testis Laterality The side of the body where a subject's undescended testis was located. undescended_testis_history_laterality undescended testis history laterality A C177536 GDC Property Terminology C182106 Biospecimen Sequence Number A number that identifies the relative position of a biospecimen in a series of samples. sample_ordinal sample ordinal A C177536 GDC Property Terminology C182109 Adrenal Hormone Indicator A indication of whether expression of an adrenal hormone was found in a sample. adrenal_hormone adrenal hormone A C177536 GDC Property Terminology C182112 Cancer Model Distributor Reference Identifier The reference number assigned to a cancer model by the distributor. distributor_reference distributor reference A C177536 GDC Property Terminology C182115 Number of Days Between Index Date and Laboratory Test The number of days between an index date and the date that a laboratory test was performed. days_to_test days to test A C177536 GDC Property Terminology C182116 Data Analysis Workflow URL A URL-formatted web address the data analysis workflow. workflow_link workflow link A C177536 GDC Property Terminology C182117 Data Analysis Workflow Version The version of the workflow used in data analysis. workflow_version workflow version D C177536 GDC Property Terminology C43568 Gene Symbol A unique gene name approved by an organism specific nomenclature committee. gene_symbol gene symbol D C177536 GDC Property Terminology C87917 Microbiology Specimen Sequence Number A number that identifies the ordering relations (in time, space, etc.) in a set of microbiology specimens. sample_ordinal sample ordinal A C177537 GDC Value Terminology C103867 Norepinephrine-Secreting A finding indicating that an excess amount of norepinephrine is secreted by a tumor. Norepinephrine-Secreting | laboratory_test C25294 laboratory_test A C177537 GDC Value Terminology C103868 Normetanephrine-Secreting A finding indicating that an excess amount of normetanephrine is secreted by a tumor. Normetanephrine-Secreting | laboratory_test C25294 laboratory_test A C177537 GDC Value Terminology C103869 Epinephrine-Secreting A finding indicating that an excess amount of epinephrine is secreted by a tumor. Epinephrine-Secreting | laboratory_test C25294 laboratory_test A C177537 GDC Value Terminology C103870 Metanephrine-Secreting A finding indicating that an excess amount of metanephrine is secreted by a tumor. Metanephrine-Secreting | laboratory_test C25294 laboratory_test A C177537 GDC Value Terminology C103871 Dopamine-Secreting A finding indicating that an excess amount of dopamine is secreted by a tumor. Dopamine-Secreting | laboratory_test C25294 laboratory_test A C177537 GDC Value Terminology C103872 Methoxytyramine-Secreting A finding indicating that an excess amount of methoxytyramine is secreted by a tumor. Methoxytyramine-Secreting | laboratory_test C25294 laboratory_test A C177537 GDC Value Terminology C104785 PDPN Gene This gene plays a role in cell shape. PDPN | gene_symbol C173595 gene_symbol A C177537 GDC Value Terminology C105522 Unit Per Gram Hemoglobin Unit of arbitrary substance concentration (biologic activity concentration) defined as the concentration of one unit per gram of hemoglobin. U/g Hb | test_units C67415 test_units A C177537 GDC Value Terminology C106015 SERPINA9 Gene This gene is involved in trypsin activity regulation. GCET1 | gene_symbol C173595 gene_symbol A C177537 GDC Value Terminology C106505 Cancer Antigen 72-4 Measurement The determination of the amount of the cancer antigen 72-4 present in a sample. TAG-72 | laboratory_test C25294 laboratory_test A C177537 GDC Value Terminology C111066 Orchiopexy A surgical procedure in which an undescended testis is fixated inside the scrotum. Orchiopexy | undescended_testis_corrected_method C182101 undescended_testis_corrected_method A C177537 GDC Value Terminology C117873 Subcarinal Lymph Node A lymph node located in the thoracic cavity between the lungs. It is bordered by the carina of the trachea, lower lobe bronchus on the left and the bronchus intermedius on the right. Lymph Node, Subcarinal | metastasis_at_diagnosis_site C177625 metastasis_at_diagnosis_site A C177537 GDC Value Terminology C122858 Cytokeratin-6 Staining Method An immunohistochemical technique used to detect the presence of cytokeratin-6 in a tissue sample. Cytokeratin 6 | laboratory_test C25294 laboratory_test A C177537 GDC Value Terminology C122859 Cytokeratin-5 Staining Method An immunohistochemical technique used to detect the presence of cytokeratin-5 in a tissue sample. Cytokeratin 5 | laboratory_test C25294 laboratory_test A C177537 GDC Value Terminology C123856 CALB2 Gene This gene is involved in calcium ion homeostasis. CALB2 | gene_symbol C173595 gene_symbol A C177537 GDC Value Terminology C131459 Microsatellite Stable Indicates that no positive loci have been detected in the microsatellite instability (MSI) biomarkers in a sample. MSS | msi_status C139285 msi_status A C177537 GDC Value Terminology C142330 Hepatitis C Virus RNA Measurement The determination of the amount of hepatitis C virus RNA present in a sample. Hepatitis C Virus RNA | viral_hepatitis_serologies C177609 viral_hepatitis_serologies A C177537 GDC Value Terminology C153189 Transcriptomics A study of the complete set of RNA transcripts that are produced by the genome, under specific circumstances or in a specific cell. Transcriptome Profiling | data_category C175886 data_category A C177537 GDC Value Terminology C156018 Archive A place or collection containing records, documents, or other materials, especially those of historical interest. Archive | data_category C175886 data_category A C177537 GDC Value Terminology C16237 Validation The act of validating; finding or testing the truth of something. Validation | experimental_strategy C43622 experimental_strategy A C177537 GDC Value Terminology C175747 Befotertinib An orally available inhibitor of the epidermal growth factor receptor (EGFR) mutant form T790M, with potential antineoplastic activity. Upon administration, befotertinib specifically binds to and inhibits EGFR T790M, a secondarily acquired resistance mutation, which prevents EGFR-mediated signaling and leads to cell death in EGFR T790M-expressing tumor cells. Compared to some other EGFR inhibitors, befotertinib may have therapeutic benefits in tumors with T790M-mediated drug resistance. EGFR, a receptor tyrosine kinase that is mutated in many tumor cell types, plays a key role in tumor cell proliferation and tumor vascularization. EGFR Mutant-specific Inhibitor D-0316 | therapeutic_agents C1909 therapeutic_agents A C177537 GDC Value Terminology C178240 BG8 IHC Staining Method An immunohistochemical technique utilizing the mouse monoclonal antibody BG8, which is directed against the type 2 fucosylated antigen Lewis Y (LeY). BG8 specifically binds to LeY, a blood group Lewis carbohydrate determinant expressed on certain glycolipids and glycoproteins. In healthy subjects, LeY is expressed in low levels by a few types of epithelial cells; however, it is aberrantly expressed in high levels in many carcinomas. This method is use in the detection of certain tumors, such as carcinomas of the breast, lung, and colon. Additionally, it may distinguish neoplasms derived from mesothelium from other epithelial-derived neoplasms. BG8 | laboratory_test C25294 laboratory_test A C177537 GDC Value Terminology C18421 EPCAM Gene This gene is involved in calcium-independent cellular adhesion and in the regulation of immune responses. EPCAM | gene_symbol C173595 gene_symbol A C177537 GDC Value Terminology C25695 Submission The act of referring for judgment or consideration by others; the act of handing over something. submitted | state C182054 state A C177537 GDC Value Terminology C26556 DNTT Gene This gene is involved in DNA synthesis. It also plays a role in the generation of antigen diversity in pre-B and pre-T lymphocytes during early differentiation. DNTT | gene_symbol C173595 gene_symbol A C177537 GDC Value Terminology C26598 PTGS2 Gene This gene is involved in mitogenesis, inflammation and angiogenesis. PTGS2 | gene_symbol C173595 gene_symbol A C177537 GDC Value Terminology C2703 Mistletoe Extract An extract of the whole plant Viscum album (mistletoe) with potential biological response modifier (BRM) activity. Mistletoe extract may both stimulate the antitumoral functions of the immune system and have a direct toxic effect on tumor cells. (NCI04) Mistletoe Extract | therapeutic_agents C1909 therapeutic_agents A C177537 GDC Value Terminology C36318 Microsatellite Instability Genomic instability associated with the presence of hypermutability in specific genetic marker regions resulting from defective DNA mismatch repair. MSI | msi_status C139285 msi_status A C177537 GDC Value Terminology C42576 Kilogram per Cubic Meter A SI derived unit of mass concentration defined as the concentration of one kilogram of a substance per unit volume of the mixture equal to one cubic meter, or the concentration of one milligram of a substance per unit volume of the mixture equal to one milliliter, or one gram of a substance per one liter of the mixture. It is also a unit of mass density (volumic mass) defined as the density of substance which mass equal to one milligram occupies the volume one milliliter. g/L | test_units C67415 test_units A C177537 GDC Value Terminology C42729 Review The act of appraisal, evaluation, or analysis. review | state C182054 state A C177537 GDC Value Terminology C45834 Pancreatic Neuroendocrine Microadenoma A well differentiated pancreatic neuroendocrine tumor which measures less than 0.5 cm in diameter and it is not associated with a hormonal syndrome. Pancreatic endocrine tumor, benign | primary_diagnosis || Pancreatic microadenoma | primary_diagnosis C177621 primary_diagnosis A C177537 GDC Value Terminology C47845 FASTA Format A sequence in FASTA format consists of a single-line description, followed by lines of sequence data. The first character of the description line is a greater-than (">") symbol in the first column. Sequences are represented in the standard IUB/IUPAC single letter amino acid and nucleic acid codes, with a single hyphen or dash being used to represent a gap of indeterminate length; in amino acid sequences asterix ("*") can represent a translation stop. FASTA | data_format C42761 data_format A C177537 GDC Value Terminology C48177 Processing The act of preparing or putting through a prescribed procedure. processing | state C182054 state A C177537 GDC Value Terminology C48326 Red The hue of the long-wave end of the visible spectrum, evoked in the human observer by radiant energy with wavelengths of approximately 630 to 750 nanometers; any of a group of colors that may vary in lightness and saturation and whose hue resembles that of blood Red | channel C181706 channel A C177537 GDC Value Terminology C48508 Micromole per Liter A unit of concentration (molarity unit) equal to one one-millionth of a mole (10E-6 mole) of solute per one liter of solution. umol/L | test_units C67415 test_units A C177537 GDC Value Terminology C49069 Open Affording unobstructed entrance and exit; affording free passage or access; accessible to all. open | state C182054 state A C177537 GDC Value Terminology C49070 Closed Not affording passage or access; blocked against entry. closed | state C182054 state A C177537 GDC Value Terminology C61398 Radiation Exposure Exposure to radioactive materials or ionizing radiation, whether by external irradiation, contact or contamination with radioactive material, or incorporation of radioactive materials, as in the case of certain diagnostic procedures. Radiation | exposure_type C157103 exposure_type A C177537 GDC Value Terminology C62669 Proteomic Profiling A laboratory procedure that determines both the identity and levels of expression of the proteins in a biological sample or specimen. Proteome Profiling | data_category C175886 data_category A C177537 GDC Value Terminology C63480 Protein Expression Analysis Any method of protein detection that can be used to quantify the level of a protein in a sample. Protein Expression Quantification | data_type C42645 data_type A C177537 GDC Value Terminology C64387 Millimole per Liter A unit of concentration (molarity unit) equal to one thousandth of a mole (10E-3 mole) of solute per one liter of solution. mmol/L | test_units C67415 test_units A C177537 GDC Value Terminology C64572 Microgram per Milliliter A metric unit of mass concentration defined as the concentration of one gram of a substance per unit volume of the mixture equal to one cubic meter. The concept also refers to the metric unit of mass density (volumic mass) defined as the density of a substance which mass equal to one gram occupies the volume of one cubic meter. mcg/mL | test_units || mg/L | test_units C67415 test_units A C177537 GDC Value Terminology C64783 Gram per Deciliter A unit of mass concentration defined as the concentration of one gram of a substance per unit volume of the mixture equal to one deciliter (100 milliliters). The concept also refers to the metric unit of mass density (volumic mass) defined as the density of substance which mass equal to one gram occupies the volume one deciliter. g/dL | test_units C67415 test_units A C177537 GDC Value Terminology C64850 Hepatitis B Virus Surface Antigen Measurement A determination of the presence of hepatitis B virus surface antigen. Hepatitis B Surface Antigen | viral_hepatitis_serologies C177609 viral_hepatitis_serologies A C177537 GDC Value Terminology C66721 Levoleucovorin Calcium A levo isoform of leucovorin calcium with antineoplastic activity. Levoleucovorin is an active metabolite of folic acid, which does not require metabolism by dihydrofolate reductase. This agent counteracts the toxic effects of other folic acid derivative agents, rescuing the patient while permitting the antitumor activity of the folate antagonist. This agent also potentiates the effects of fluorouracil and its derivatives by stabilizing the binding of the drug's metabolite to its target enzyme, thus prolonging drug activity. Levoleucovorin Calcium | therapeutic_agents C1909 therapeutic_agents A C177537 GDC Value Terminology C67015 Milligram per Deciliter A unit of mass concentration defined as the concentration of one milligram of a substance in unit volume of the mixture equal to one cubic deciliter or 100 cubic centimeters. It is also a unit of mass density (volumic mass) defined as the density of substance which mass equal to one milligram occupies the volume one cubic deciliter or 100 cubic centimeters. mg/dL | test_units C67415 test_units A C177537 GDC Value Terminology C67244 Thousand Cells per Microliter A unit of cell concentration expressed as a number of cells in thousands per unit volume equal to one microliter. x10^3 cells/mcL | test_units C67415 test_units A C177537 GDC Value Terminology C67249 Billion Cells per Liter A unit of cell concentration expressed as a number of cells in billions per unit volume equal to one liter. x10^9 cells/L | test_units C67415 test_units A C177537 GDC Value Terminology C67397 Microkatal per Liter Unit of catalytic activity concentration defined as activity equal to one millionth of katal per one liter of the system volume. ukat/L | test_units C67415 test_units A C177537 GDC Value Terminology C67456 Unit per Liter An arbitrary unit of substance concentration equal to the concentration at which one liter of mixture contains one unit of a substance. U/L | test_units C67415 test_units A C177537 GDC Value Terminology C74711 Hepatitis B Surface Antibody Measurement The determination of the surface antibody reaction of a sample to the Hepatitis B virus. HBV Surface Antibody | viral_hepatitis_serologies C177609 viral_hepatitis_serologies A C177537 GDC Value Terminology C77607 Unit per Milliliter An arbitrary unit of substance content expressed in unit(s) per milliliter. U/mL | test_units C67415 test_units A C177537 GDC Value Terminology C92535 Hepatitis C Antibody Measurement A quantitative measurement of the antibody reaction of a biological specimen to the Hepatitis C virus. Hepatitis C Antibody | viral_hepatitis_serologies C177609 viral_hepatitis_serologies A C177537 GDC Value Terminology C96592 Circulating Endothelial Cell Count The determination of the amount of circulating endothelial cells present in a sample. Circulating Endothelial Cells | laboratory_test C25294 laboratory_test A C177537 GDC Value Terminology C96660 Hepatitis B Virus Core Antibody Measurement The determination of the amount of Hepatitis B virus core antibody present in a sample. HBV Core Antibody | viral_hepatitis_serologies C177609 viral_hepatitis_serologies C C177537 GDC Value Terminology C101088 ARID2 Gene This gene is involved in both transcriptional regulation and chromatin remodeling. ARID2 | gene_symbol || ARID2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101091 BCOR Gene This gene plays a role in the repression of gene transcription. BCOR | gene_symbol || BCOR | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101095 CDK12 Gene This gene is involved in protein phosphorylation, RNA splicing and transcription elongation. CDK12 | gene_symbol || CDK12 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101098 NUTM2A Gene This gene has an unknown function. NUTM2A | gene_symbol || NUTM2A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101101 NUTM2B Gene The function of this gene is unknown. NUTM2B | gene_symbol || NUTM2B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101104 FBXO11 Gene This gene plays a role in the recognition of proteins to be ubiquitinylated. FBXO11 | gene_symbol || FBXO11 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101107 HEY1 Gene This gene is involved in both transcription factor binding and transcriptional repression. HEY1 | gene_symbol || HEY1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101110 SRSF2 Gene This gene plays a role in RNA splicing. SRSF2 | gene_symbol || SRSF2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101113 U2AF1 Gene This gene is involved in the splicing of mRNA. U2AF1 | gene_symbol || U2AF1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101116 YWHAE Gene This gene plays a role in signaling. YWHAE | gene_symbol || YWHAE | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101120 ZRSR2 Gene This gene is involved in mRNA processing. ZRSR2 | gene_symbol || ZRSR2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101126 STIL Gene This gene plays a role in both cellular proliferation and embryonic development. STIL | gene_symbol || STIL | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101144 SYP Gene This gene is involved in vesicle targeting and synaptic plasticity. SYP | gene_symbol || SYP | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101346 STAG2 Gene This gene is involved in cell division. STAG2 | gene_symbol || STAG2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101425 KIF5B Gene This gene is involved in the transport of vesicles along microtubules. KIF5B | gene_symbol || KIF5B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101428 WDCP Gene This gene plays a role in binding to tyrosine-protein kinase HCK. WDCP | gene_symbol || WDCP | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101431 SDC4 Gene This gene is involved in cell-matrix interactions. SDC4 | gene_symbol || SDC4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101434 SLC34A2 Gene This gene plays a role in phosphate transport. SLC34A2 | gene_symbol || SLC34A2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101440 CAMTA1 Gene This gene is involved in both DNA binding and transcription. CAMTA1 | gene_symbol || CAMTA1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101443 H3-3A Gene This gene is involved in chromatin structure. H3F3A | gene_symbol || H3F3A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101446 LRIG3 Gene This gene may be involved in signaling. LRIG3 | gene_symbol || LRIG3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101449 PHF6 Gene This gene plays a role in transcriptional regulation. PHF6 | gene_symbol || PHF6 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101452 ECT2L Gene This gene may be involved in guanine nucleotide exchange. ECT2L | gene_symbol || ECT2L | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101494 PPFIBP1 Gene This gene plays a role in protein-protein interactions and cell-matrix adhesion. PPFIBP1 | gene_symbol || PPFIBP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101559 SGK1 Gene This gene plays a role in both protein phosphorylation and cellular stress response. SGK1 | gene_symbol || SGK1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101565 DDX3X Gene This gene is involved in RNA binding. DDX3X | gene_symbol || DDX3X | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101617 ZMYM3 Gene This gene is involved in chromatin modification. ZMYM3 | gene_symbol || ZMYM3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101638 TBX3 Gene This gene is involved in both transcriptional repression and limb development. TBX3 | gene_symbol || TBX3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101646 FOXA1 Gene This gene plays a role in the modulation of gene expression. FOXA1 | gene_symbol || FOXA1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101721 EED Gene This gene plays a role in the negative regulation of transcription. EED | gene_symbol || EED | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C101732 H3C2 Gene This gene is involved in chromatin structure. HIST1H3B | gene_symbol || HIST1H3B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C102517 PREX2 Gene This gene is involved in guanine nucleotide exchange. PREX2 | gene_symbol || PREX2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C102520 ARID1B Gene This gene plays a role in both chromatin remodeling and transcriptional regulation. ARID1B | gene_symbol || ARID1B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C102523 MAP3K13 Gene This gene is involved in both protein phosphorylation and signaling. MAP3K13 | gene_symbol || MAP3K13 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C102534 SPOP Gene This gene may be involved in both transcriptional repression and protein ubiquitination. SPOP | gene_symbol || SPOP | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C102796 DNM2 Gene This gene plays a role in both GTP hydrolysis and microtubule organization. DNM2 | gene_symbol || DNM2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C102802 SH2B3 Gene This gene plays a role in T-cell activation. SH2B3 | gene_symbol || SH2B3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C102901 PPP6C Gene This gene plays a role in both protein dephosphorylation and signaling. PPP6C | gene_symbol || PPP6C | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C102939 CD99 Gene This gene plays a role in the cell adhesion process. CD99 | gene_symbol || CD99 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C102968 ID3 Gene This gene plays a role in transcriptional repression. ID3 | gene_symbol || ID3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C103873 SDHA Gene This gene is involved in the mitochondrial respiratory chain. SDHA | gene_symbol || SDHA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C104128 CCR7 Gene This gene plays a role in immune function. CCR7 | gene_symbol || CCR7 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C104212 PTPN13 Gene This gene is involved in both protein dephosphorylation and signal transduction. PTPN13 | gene_symbol || PTPN13 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C104303 EPAS1 Gene This gene plays a role in the cellular response to hypoxia. EPAS1 | gene_symbol || EPAS1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C104587 NT5C2 Gene This gene plays a role in purine metabolism. NT5C2 | gene_symbol || NT5C2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C104651 MIB1 Gene This gene is involved in both ubiquitination and cell signaling. MIB1 | gene_symbol C173595 gene_symbol C C177537 GDC Value Terminology C104821 PLCG1 Gene This gene is involved in both intracellular signaling and second messenger production. PLCG1 | gene_symbol || PLCG1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C105393 CCNC Gene This gene plays a role in the modulation of gene transcription. CCNC | gene_symbol || CCNC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C105605 ZEB1 Gene This gene is involved in the transcriptional repression of interleukin 2. ZEB1 | gene_symbol || ZEB1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C106067 RSPO2 Gene This gene plays a role in both Wnt signaling and embryonic morphogenesis. RSPO2 | gene_symbol || RSPO2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C106113 PTPRK Gene This gene is involved in receptor signaling, cell-cell contact and cell migration. PTPRK | gene_symbol || PTPRK | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C106190 NTHL1 Gene This gene plays a role in nucleotide-excision DNA repair. NTHL1 | gene_symbol || NTHL1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C106224 POLD1 Gene This gene is involved in DNA replication and proofreading. POLD1 | gene_symbol || POLD1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C106232 POLE Gene This gene is involved in both DNA replication and DNA base-excision repair. POLE | gene_symbol || POLE | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C106340 FAM131B Gene This gene has not been characterized. FAM131B | gene_symbol || FAM131B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C106358 ZNF444 Gene This gene is involved in both transcriptional regulation and DNA binding. ZNF444 | gene_symbol || ZNF444 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C106606 MAP2K2 Gene This gene plays a role in both protein phosphorylation and signal transduction. MAP2K2 | gene_symbol || MAP2K2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C106635 SETBP1 Gene This gene may be involved in the modulation of protein SET activity. SETBP1 | gene_symbol || SETBP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C107646 TRAF7 Gene This gene is involved in both MAPK signaling and protein ubiquitination. TRAF7 | gene_symbol || TRAF7 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C107649 RNF43 Gene This gene is involved in both protein ubiquitination and the Wnt signaling pathway. RNF43 | gene_symbol || RNF43 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C107652 RPL5 Gene This gene plays a role in ribosome assembly. RPL5 | gene_symbol || RPL5 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C107655 POT1 Gene This gene plays a role in the regulation of telomere length. POT1 | gene_symbol || POT1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C107658 CNOT3 Gene This gene is involved in mRNA degradation, miRNA-mediated repression, translational regulation and general transcription regulation. CNOT3 | gene_symbol || CNOT3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C107661 STRN Gene This gene may play a role in cell scaffolding or calcium signaling. STRN | gene_symbol || STRN | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C111830 LRP1B Gene This gene plays a role in low density lipoprotein metabolism. LRP1B | gene_symbol || LRP1B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C111841 EPHA7 Gene This gene plays a role in mediation of developmental processes. EPHA7 | gene_symbol || EPHA7 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C111928 UBR5 Gene This gene plays a role in protein ubiquitination. UBR5 | gene_symbol || UBR5 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C111937 QKI Gene This gene is involved in both the biosynthesis and maintenance of mRNA. QKI | gene_symbol || QKI | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C112105 KEAP1 Gene This gene is involved in ubiquitin-mediated protein degradation. KEAP1 | gene_symbol || KEAP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C112905 SALL4 Gene This gene plays a role in both transcriptional regulation and stem cell maintenance. SALL4 | gene_symbol || SALL4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C113585 FLNA Gene This gene is involved in remodeling of the cytoskeleton. FLNA | gene_symbol || FLNA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C113760 H3-3B Gene This gene plays a role in nucleosome assembly. H3F3B | gene_symbol || H3F3B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C113762 ATP1A1 Gene This gene is involved in both ion transport and ATP metabolism. ATP1A1 | gene_symbol || ATP1A1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C113765 ATP2B3 Gene This gene plays a role in ATP-dependent calcium transport. ATP2B3 | gene_symbol || ATP2B3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C113769 CACNA1D Gene This gene is involved in voltage-dependent calcium transport. CACNA1D | gene_symbol || CACNA1D | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C114452 RANBP2 Gene This gene is involved in both SUMOylation and nuclear transport. RANBP2 | gene_symbol || RANBP2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C114529 GRM3 Gene This gene is involved in ligand-depending signaling. GRM3 | gene_symbol || GRM3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C114743 BCL2L12 Gene This gene is involved in the regulation of apoptosis. BCL2L12 | gene_symbol || BCL2L12 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C115310 SPEN Gene This gene plays a role in hormone-mediated transcriptional regulation. SPEN | gene_symbol || SPEN | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C115382 RBM10 Gene This gene is involved in RNA binding and processing. RBM10 | gene_symbol || RBM10 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C115424 ZFHX3 Gene This gene is involved in myoblast and neuronal differentiation. ZFHX3 | gene_symbol || ZFHX3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C115994 BCLAF1 Gene Human BCLAF1 wild-type allele is located within 6q22-q23 and is approximately 33 kb in length. This allele, which encodes Bcl-2-associated transcription factor 1 protein, plays a role in both apoptosis promotion and the repression of transcription. BCLAF1 | gene_symbol || BCLAF1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C116296 ASXL2 Gene This gene plays a role in both chromatin modification and the positive regulation of transcription. ASXL2 | gene_symbol || ASXL2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C116411 ISX Gene This gene is involved in gene expression regulation in the intestine. ISX | gene_symbol || ISX | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C117001 APOBEC3B Gene This gene plays a role in viral DNA cytosine deamination. APOBEC3B | gene_symbol || APOBEC3B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C117094 MAML3 Gene This gene plays a role in both transcriptional activation and signaling. MAML3 | gene_symbol || MAML3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C118285 Denifanstat An orally bioavailable fatty acid synthase (FASN) inhibitor, with potential antineoplastic activity. Upon administration, denifanstat binds to and blocks FASN, which prevents the synthesis of palmitate needed for tumor cell growth and survival. This leads to a reduction in cell signaling, an induction of tumor cell apoptosis and the inhibition of cell proliferation in susceptible tumor cells. FASN, an enzyme responsible for the de novo synthesis of palmitic acid, is overexpressed in tumor cells and plays a key role in tumor metabolism, lipid signaling, tumor cell survival and drug resistance; tumor cells are dependent on increased fatty acid production for their enhanced metabolic needs and rapid growth. FASN Inhibitor TVB-2640 | therapeutic_agents C1909 therapeutic_agents C C177537 GDC Value Terminology C118319 ZNRF3 Gene This gene is involved in protein ubiquitination and Wnt pathway inhibition. ZNRF3 | gene_symbol || ZNRF3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C118358 Exoresection A surgical technique for the transscleral resection of large, anteriorly located uveal melanomas with ciliary body and/or iris involvement. This approach is most common when conservative therapy is either unlikely to help, or likely to cause complications. Exoresection | method_of_diagnosis || Local Resection (Exoresection; wall resection) | method_of_sample_procurement C177576 || C70700 method_of_diagnosis || method_of_sample_procurement C C177537 GDC Value Terminology C119652 KNSTRN Gene This gene plays a role in both mitotic spindle formation and chromosome segregation. KNSTRN | gene_symbol || KNSTRN | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C122560 DNAJB1 Gene This gene plays a role in the regulation of protein folding. DNAJB1 | gene_symbol || DNAJB1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C122823 ETNK1 Gene This gene plays a role in phospholipid biosynthesis. ETNK1 | gene_symbol || ETNK1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C122875 DCTN1 Gene This gene is involved in the modulation of retrograde transport of cytoplasmic organelles and vesicles. DCTN1 | gene_symbol || DCTN1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C122878 ZCCHC8 Gene This gene plays a role in RNA binding. ZCCHC8 | gene_symbol || ZCCHC8 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C122881 MYO5A Gene This gene is involved in vesicle transport along actin filaments. MYO5A | gene_symbol || MYO5A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C122884 LSM14A Gene This gene plays a role in the storage of mRNA. LSM14A | gene_symbol || LSM14A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C122887 CEP89 Gene This gene is involved in cilia formation. CEP89 | gene_symbol || CEP89 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C122890 PWWP2A Gene This gene may play a role in protein-protein or protein-DNA interactions. PWWP2A | gene_symbol || PWWP2A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C122903 NAB2 Gene This gene plays a role in the repression of gene transcription. NAB2 | gene_symbol || NAB2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C122906 SHTN1 Gene This gene is involved in neuronal polarization. SHTN1 | gene_symbol || SHTN1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C122909 PTPRB Gene This gene is involved in dephosphorylation of proteins. PTPRB | gene_symbol || PTPRB | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C123160 Lepidic Adenocarcinoma A lung adenocarcinoma characterized by the presence of mildly and moderately differentiated adenocarcinoma cells across the alveolar walls with at least one focus of invasive carcinoma measuring more than 5 mm in greatest dimension. Lepidic predominant adenocarcinoma | primary_diagnosis C177621 primary_diagnosis C C177537 GDC Value Terminology C124048 DUX4L1 Gene Human DUX4L1 gene is located in the vicinity of 4q35 and is approximately 2 kb in length. The product is a processed pseudogene that produces an RNA transcript, but does not encode a protein product. This gene is within a D4Z4 repeat array; contraction of this macrosatellite repeat is associated with facioscapulohumeral muscular dystrophy (FSHD). DUX4L1 | gene_symbol || DUX4L1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C12414 Bladder The distensible sac-like organ that functions as a reservoir of urine, collecting from the kidneys and eliminating via the urethra. Bladder | biospecimen_anatomic_site || Bladder | hysterectomy_margins_involved || Bladder | metastasis_at_diagnosis_site || Bladder | primary_site || Bladder | treatment_anatomic_site || Bladder, NOS | progression_or_recurrence_anatomic_site || Bladder, NOS | site_of_resection_or_biopsy || Bladder, NOS | tissue_or_organ_of_origin C156421 || C156422 || C158874 || C171435 || C177570 || C177594 || C177625 || C70729 site_of_resection_or_biopsy || tissue_or_organ_of_origin || primary_site || biospecimen_anatomic_site || progression_or_recurrence_anatomic_site || hysterectomy_margins_involved || metastasis_at_diagnosis_site || treatment_anatomic_site C C177537 GDC Value Terminology C126274 Fuzuloparib An orally available inhibitor of poly (ADP-ribose) polymerase (PARP) types 1 and 2, with potential antineoplastic activity. Upon oral administration, fuzuloparib inhibits PARP 1 and 2 activity, which inhibits PARP-mediated repair of damaged DNA via the base excision repair (BER) pathway, enhances the accumulation of DNA strand breaks, promotes genomic instability, and leads to an induction of apoptosis. The PARP family of proteins catalyze post-translational ADP-ribosylation of nuclear proteins, which then transduce signals to recruit other proteins to repair damaged DNA. PARP inhibition may enhance the cytotoxicity of DNA-damaging agents and may reverse tumor cell chemoresistance and radioresistance. Fluzoparib | therapeutic_agents C1909 therapeutic_agents C C177537 GDC Value Terminology C126774 ROBO2 Gene This gene plays a role in ligand binding, axon guidance and cell migration. ROBO2 | gene_symbol || ROBO2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C12683 Bronchus Tubular structure in continuation with the trachea, serving as air passage. It terminates in the lung (terminal bronchiole). Bronchus | biospecimen_anatomic_site || Bronchus | metastasis_at_diagnosis_site || Bronchus | treatment_anatomic_site C171435 || C177625 || C70729 biospecimen_anatomic_site || metastasis_at_diagnosis_site || treatment_anatomic_site C C177537 GDC Value Terminology C128251 CHD4 Gene This gene is involved in ATP-dependent chromatin remodeling. CHD4 | gene_symbol || CHD4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C128254 FAT4 Gene This gene plays a role in planar cell polarity. FAT4 | gene_symbol || FAT4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C128257 LZTR1 Gene This gene may be involved in Golgi stabilization, embryogenesis or transcriptional regulation. LZTR1 | gene_symbol || LZTR1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C128854 MUC4 Gene This gene is involved in both cell adhesion and receptor signaling. MUC4 | gene_symbol || MUC4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C129065 CCR4 Gene This gene is involved in chemokine-dependent G protein-coupled receptor signaling. CCR4 | gene_symbol || CCR4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C131224 STAG1 Gene This gene plays a role in sister chromatid binding. STAG1 | gene_symbol || STAG1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C131268 BCORL1 Gene This gene plays a role in the inhibition of gene expression. BCORL1 | gene_symbol || BCORL1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C131315 EIF1AX Gene This gene is involved in translation initiation and efficiency. EIF1AX | gene_symbol || EIF1AX | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C131801 POLQ Gene This gene is involved in DNA synthesis and repair. POLQ | gene_symbol || POLQ | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C132170 MB21D2 Gene This gene plays a role in protein-protein interactions. MB21D2 | gene_symbol || MB21D2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C132328 BCL9L Gene This gene plays a role in the coactivation of gene transcription. BCL9L | gene_symbol || BCL9L | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C132851 Evorpacept A variant of signal regulatory protein alpha (SIRPa) that antagonizes the human cell surface antigen CD47, with potential phagocytosis-inducing, immunostimulating and antineoplastic activities. Upon administration, evorpacept binds to CD47 expressed on tumor cells and prevents the interaction of CD47 with its ligand SIRPa, a protein expressed on phagocytic cells. This prevents CD47/SIRPa-mediated signaling and abrogates the CD47/SIRPa-mediated inhibition of phagocytosis. This induces pro-phagocytic signaling mediated by the binding of the pro-phagocytic signal calreticulin (CRT), which is specifically expressed on the surface of tumor cells, to low-density lipoprotein (LDL) receptor-related protein (LRP), expressed on macrophages. This results in macrophage activation and the specific phagocytosis of tumor cells. In addition, blocking CD47 signaling activates both an anti-tumor cytotoxic T-lymphocyte (CTL) immune response and T cell-mediated killing of CD47-expressing tumor cells. CD47, also called integrin-associated protein (IAP), is a tumor-associated antigen (TAA) expressed on normal, healthy hematopoietic stem cells (HSC) and overexpressed on the surface of a variety of cancer cells. Expression of CD47, and its interaction with SIRPa, leads to the inhibition of macrophage activation and protects cancer cells from phagocytosis, which allows cancer cells to proliferate. CD47 Antagonist ALX148 | therapeutic_agents C1909 therapeutic_agents C C177537 GDC Value Terminology C13332 Bilateral Affecting both sides of the body or a matched pair of organs. Bilateral | biospecimen_laterality || Bilateral | laterality || Bilateral | undescended_testis_corrected_laterality || Bilateral | undescended_testis_history_laterality C177605 || C181723 || C182102 || C25185 biospecimen_laterality || undescended_testis_corrected_laterality || undescended_testis_history_laterality || laterality C C177537 GDC Value Terminology C142827 Primary Pulmonary Myxoid Sarcoma with EWSR1-CREB1 Fusion A sarcoma that arises from the lung. It is related to a bronchus and is often predominantly endobronchial. It is characterized by the proliferation of round and spindle cells within a myxoid stroma. It is associated with the presence of an EWSR1-CREB1 fusion gene. Pulmonary myxoid sarcoma with EWSR1-CREB1 translocation | primary_diagnosis C177621 primary_diagnosis C C177537 GDC Value Terminology C143031 A1CF Gene This gene is involved in the deamination of APOB mRNA. A1CF | gene_symbol || A1CF | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143036 DCAF12L2 Gene This gene may play a role in protein complex formation. DCAF12L2 | gene_symbol || DCAF12L2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143039 CYSLTR2 Gene This gene is involved in cysteinyl leukotriene binding and signal transduction. CYSLTR2 | gene_symbol || CYSLTR2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143042 CSMD3 Gene This gene plays a role in neuronal development. CSMD3 | gene_symbol || CSMD3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143049 CRNKL1 Gene This gene is involved in RNA binding and pre-mRNA splicing. CRNKL1 | gene_symbol || CRNKL1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143052 COL3A1 Gene This gene plays a role in collagen formation in connective tissues. COL3A1 | gene_symbol || COL3A1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143056 CNBD1 Gene This gene is involved in cyclic nucleotide binding. CNBD1 | gene_symbol || CNBD1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143061 CHST11 Gene This gene plays a role in the metabolism of chondroitin sulfate. CHST11 | gene_symbol || CHST11 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143064 LARP4B Gene This gene is involved in RNA metabolism and translation. LARP4B | gene_symbol || LARP4B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143069 POLG Gene This gene plays a role in the replication of mitochondrial DNA. POLG | gene_symbol || POLG | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143072 PABPC1 Gene This gene is involved in binding to poly(A)RNA. PABPC1 | gene_symbol || PABPC1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143075 NBEA Gene This gene plays a role in membrane-targeting of protein kinase A. NBEA | gene_symbol || NBEA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143078 S100A7 Gene This gene is involved in both calcium binding and antimicrobial activity. S100A7 | gene_symbol || S100A7 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143082 RGPD3 Gene This gene may play a role in the localization of the GTPase Ran. RGPD3 | gene_symbol || RGPD3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143090 PRPF40B Gene This gene may be involved in mRNA splicing. PRPF40B | gene_symbol || PRPF40B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143093 CDH10 Gene This gene plays a role in the modulation of neuronal cell shape and cell-cell adhesion. CDH10 | gene_symbol || CDH10 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143096 CDH17 Gene This gene is involved in cell-cell adhesion and intestinal proton-dependent peptide transport. CDH17 | gene_symbol || CDH17 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143100 ZNF429 Gene This gene may play a role in the regulation of gene transcription. ZNF429 | gene_symbol || ZNF429 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143103 ZNF479 Gene This gene may play a role in the regulation of gene transcription. ZNF479 | gene_symbol || ZNF479 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143106 WNK2 Gene This gene plays a role in electrolyte homeostasis, cell signaling, cell survival, and cellular proliferation. WNK2 | gene_symbol || WNK2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143109 FAM47C Gene This gene has no known function. FAM47C | gene_symbol || FAM47C | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143112 FAM135B Gene This gene may play a role in the metabolism of lipids. FAM135B | gene_symbol || FAM135B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143115 CTNNA2 Gene This gene is involved in cell-cell adhesion and cellular differentiation in the nervous system. CTNNA2 | gene_symbol || CTNNA2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143118 RGS7 Gene This gene plays a role in the inhibition of both G protein-coupled receptor signaling and signal transduction. RGS7 | gene_symbol || RGS7 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143121 PRDM2 Gene This gene is involved in both methylation of histone H3 and transcriptional regulation. PRDM2 | gene_symbol || PRDM2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143124 FOXR1 Gene This gene plays a role in DNA binding and transcriptional regulation. FOXR1 | gene_symbol || FOXR1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143127 FKBP9 Gene This gene is involved in chaperone-mediated protein folding. FKBP9 | gene_symbol || FKBP9 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143130 FBLN2 Gene This gene plays a role in protein-protein interactions in the extracellular matrix. FBLN2 | gene_symbol || FBLN2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C143133 FAT3 Gene This gene is involved in cell adhesion and neurite development. FAT3 | gene_symbol || FAT3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C148532 Amdizalisib An orally bioavailable selective inhibitor of the delta isoform of phosphatidylinositide 3-kinase (phosphoinositide 3'-kinase delta; PI3Kd; PI3K-d), with potential antineoplastic activity. Upon oral administration, amdizalisib selectively binds to and inhibits PI3Kd, and prevents the activation of the PI3Kd/AKT signaling pathway, and B-cell activation. This both decreases proliferation and induces cell death in PI3Kd-overexpressing tumor cells. PI3Kd plays a key role in the B-cell receptor (BCR) signaling pathway and the proliferation of hematologic cancer cells. The targeted inhibition of PI3Kd is designed to preserve PI3K signaling in normal, non-neoplastic cells and thereby to minimize serious side effects. PI3Kd, an enzyme often overexpressed in cancer cells, plays a crucial role in tumor cell regulation and survival. PI3K-delta Inhibitor HMPL 689 | therapeutic_agents C1909 therapeutic_agents C C177537 GDC Value Terminology C15288 Orchiectomy Surgical removal of one or both testicles. Orchiectomy | method_of_sample_procurement || Testis Removed | undescended_testis_corrected_method C182101 || C70700 undescended_testis_corrected_method || method_of_sample_procurement C C177537 GDC Value Terminology C15445 Hormone Therapy Various treatment modalities that produce the desired therapeutic effect by means of change of hormone/hormones level. Hormone Therapy | therapeutic_agents || Hormone Therapy | treatment_type || Hormones | undescended_testis_corrected_method C182101 || C1909 || C25218 undescended_testis_corrected_method || therapeutic_agents || treatment_type C C177537 GDC Value Terminology C162620 Autologous Anti-CD19/CD22 CAR T-cells AUTO3 A preparation of autologous T-lymphocytes that have been transduced with a bicistronic retroviral vector encoding both an anti-CD19 chimeric antigen receptor (CAR) fused to OX40 co-stimulatory domain and an anti-CD22 CAR linked to the intracellular signaling domains of 4-1BB (CD137) and the zeta chain of the TCR/CD3 complex (TCRzeta; CD247; CD3zeta), optimized with a novel pentameric spacer derived from the collagen oligomeric matrix protein (COMP), with potential antineoplastic activity. Upon administration, the autologous anti-CD19/CD22 CAR T-cells AUTO3 bind to and induce selective toxicity in tumor cells expressing CD19 and CD22. CD19 and CD22, both transmembrane phosphoglycoproteins expressed on the surface of cells in the B lineage, are often overexpressed on malignant B-cells. By simultaneously targeting two B-cell antigens, this preparation may minimize relapse due to single antigen loss in patients with B-cell malignancies. Autologous Anti-CD19/CD22 CAR T-cells AUTO3 | therapeutic_agents C1909 therapeutic_agents C C177537 GDC Value Terminology C162630 HOXB1 Gene This gene is involved in the development of anterior embryonic structures and facial nerves. HOXB1 | gene_symbol || HOXB1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C16887 MYC Gene This gene plays a role in cell cycle progression and apoptosis. Cytogenetic aberrations in the gene are involved in cellular transformation and are associated with a variety of hematopoietic tumors, leukemias and lymphomas. MYC | gene_symbol || MYC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C17060 HRAS Gene This gene plays a role in signal transduction and cellular communication. HRAS | gene_symbol || HRAS | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C17084 REL Gene This gene is involved in transcriptional regulation and signal transduction through the nuclear factor kappa B NFKB signal transduction pathway. REL | gene_symbol || REL | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C171139 IGKC Gene This gene plays a role in the structure of immunoglobulin light chains. IGKC | gene_symbol C173595 gene_symbol C C177537 GDC Value Terminology C171152 Single Cell RNA Sequencing A procedure that can determine the nucleotide sequence for all of the RNA transcripts in an amplified nucleotide sample that was derived from a single cell. scRNA-Seq | library_strand C177563 || C43622 library_strand || experimental_strategy C C177537 GDC Value Terminology C17346 ABL1 Gene This gene is involved in cell adhesion, differentiation, division and stress response. ABL1 | gene_symbol || ABL1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C17358 DCC Gene This gene plays a role in the regulation of several processes that determine neuronal cell morphology. DCC | gene_symbol || DCC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C17359 TP53 Gene This gene plays a critical role in cell cycle regulation and has tumor suppressor activity. TP53 | gene_symbol || TP53 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C17360 RB1 Gene This gene is involved in the regulation of cell differentiation, growth and proliferation. RB1 | gene_symbol || RB1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C17424 NF1 Gene This gene plays a role in signal transduction and cytoskeletal remodeling. NF1 | gene_symbol || NF1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C17425 NF2 Gene This gene plays a role in cell adhesion and cytoskeletal remodeling. It is also involved in suppression of cell growth. NF2 | gene_symbol || NF2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C17567 APC Gene This gene plays a role in signal transduction. It is involved in both adhesion and migration of cells. APC | gene_symbol || APC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C17756 ERBB2 Gene This gene plays a role in cellular proliferation and is involved in the oncogenic process through amplification and/or overexpression in several cancers. ERBB2 | gene_symbol || ERBB2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C17757 EGFR Gene This gene is involved in the epidermal growth factor signal transduction pathway. EGFR | gene_symbol || EGFR | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C17782 CDKN1A Gene This gene is a regulator of cell cycle progression at the G1 phase of the cell cycle. CDKN1A | gene_symbol || CDKN1A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C17963 BCL2 Gene This gene is involved in apoptotic regulation. Overexpression of this gene promotes the pathogenesis of B-Cell lymphomas, due to anti-apoptotic activity. BCL2 | gene_symbol || BCL2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C17965 BRCA1 Gene This gene plays a role in cell cycle control, regulation of transcription and the maintenance of genomic stability. It is also involved in the inhibition of mammary cell growth. BRCA1 | gene_symbol || BRCA1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C17973 LMO2 Gene This gene plays a crucial role in hematopoietic development and is involved in transcriptional activation. LMO2 | gene_symbol || LMO2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C17998 Unknown Not known, observed, recorded; or reported as unknown by the data contributor. Unknown | ajcc_clinical_m || Unknown | ajcc_clinical_n || Unknown | ajcc_clinical_stage || Unknown | ajcc_clinical_t || Unknown | ajcc_pathologic_m || Unknown | ajcc_pathologic_n || Unknown | ajcc_pathologic_stage || Unknown | ajcc_pathologic_t || Unknown | ajcc_staging_system_edition || Unknown | alcohol_history || Unknown | alcohol_intensity || Unknown | alcohol_type || Unknown | anaplasia_present || Unknown | anaplasia_present_type || Unknown | ann_arbor_b_symptoms || Unknown | ann_arbor_clinical_stage || Unknown | ann_arbor_extranodal_involvement || Unknown | ann_arbor_pathologic_stage || Unknown | antigen || Unknown | asbestos_exposure || Unknown | barretts_esophagus_goblet_cells_present || Unknown | biospecimen_anatomic_site || Unknown | biospecimen_laterality || Unknown | biospecimen_type || Unknown | bone_marrow_malignant_cells || Unknown | burkitt_lymphoma_clinical_variant || Unknown | cause_of_death || Unknown | cause_of_death_source || Unknown | cdc_hiv_risk_factors || Unknown | chemo_concurrent_to_radiation || Unknown | child_pugh_classification || Unknown | chipseq_antibody || Unknown | chipseq_target || Unknown | chromosome || Unknown | classification_of_tumor || Unknown | coal_dust_exposure || Unknown | cog_liver_stage || Unknown | cog_neuroblastoma_risk_group || Unknown | cog_renal_stage || Unknown | cog_rhabdomyosarcoma_risk_group || Unknown | columnar_mucosa_present || Unknown | comorbidity || Unknown | comorbidity_method_of_diagnosis || Unknown | composition || Unknown | diabetes_treatment_type || Unknown | diagnosis_pathologically_confirmed || Unknown | disease_response || Unknown | disease_type || Unknown | distance_normal_to_tumor || Unknown | dysplasia_degree || Unknown | dysplasia_type || Unknown | ecog_performance_status || Unknown | eln_risk_classification || Unknown | enneking_msts_grade || Unknown | enneking_msts_metastasis || Unknown | enneking_msts_stage || Unknown | enneking_msts_tumor_site || Unknown | environmental_tobacco_smoke_exposure || Unknown | esophageal_columnar_dysplasia_degree || Unknown | esophageal_columnar_metaplasia_present || Unknown | ethnicity || Unknown | exposure_duration || Unknown | figo_stage || Unknown | first_symptom_prior_to_diagnosis || Unknown | fragmentation_enzyme || Unknown | gastric_esophageal_junction_involvement || Unknown | gene_symbol || Unknown | goblet_cells_columnar_mucosa_present || Unknown | haart_treatment_indicator || Unknown | hepatitis_sustained_virological_response || Unknown | histone_family || Unknown | histone_variant || Unknown | hormonal_contraceptive_type || Unknown | hormonal_contraceptive_use || Unknown | hormone_replacement_therapy_type || Unknown | hpv_positive_type || Unknown | hysterectomy_margins_involved || Unknown | hysterectomy_type || Unknown | igcccg_stage || Unknown | imaging_result || Unknown | immunosuppressive_treatment_type || Unknown | initial_disease_status || Unknown | inpc_grade || Unknown | inpc_histologic_group || Unknown | inrg_stage || Unknown | inss_stage || Unknown | instrument_model || Unknown | irs_group || Unknown | irs_stage || Unknown | ishak_fibrosis_score || Unknown | iss_stage || Unknown | karnofsky_performance_status || Unknown | laboratory_test || Unknown | largest_extrapelvic_peritoneal_focus || Unknown | laterality || Unknown | lost_to_followup || Unknown | lymph_node_involved_site || Unknown | lymph_node_involvement || Unknown | lymphatic_invasion_present || Unknown | margin_status || Unknown | medulloblastoma_molecular_classification || Unknown | menopause_status || Unknown | metaplasia_present || Unknown | metastasis_at_diagnosis || Unknown | metastasis_at_diagnosis_site || Unknown | method_of_diagnosis || Unknown | method_of_sample_procurement || Unknown | micropapillary_features || Unknown | mismatch_repair_mutation || Unknown | mitosis_karyorrhexis_index || Unknown | molecular_analysis_method || Unknown | morphology || Unknown | non_nodal_regional_disease || Unknown | non_nodal_tumor_deposits || Unknown | normal_tumor_genotype_snp_match || Unknown | ovarian_specimen_status || Unknown | ovarian_surface_involvement || Unknown | perineural_invasion_present || Unknown | peripancreatic_lymph_nodes_positive || Unknown | peritoneal_fluid_cytological_status || Unknown | ploidy || Unknown | pregnancy_outcome || Unknown | pregnant_at_diagnosis || Unknown | premature_at_birth || Unknown | preservation_method || Unknown | primary_diagnosis || Unknown | primary_site || Unknown | prior_treatment || Unknown | procedures_performed || Unknown | progression_or_recurrence || Unknown | progression_or_recurrence_anatomic_site || Unknown | progression_or_recurrence_type || Unknown | race || Unknown | radon_exposure || Unknown | reflux_treatment_type || Unknown | relationship_primary_diagnosis || Unknown | relationship_type || Unknown | residual_disease || Unknown | respirable_crystalline_silica_exposure || Unknown | risk_factor || Unknown | risk_factor_treatment || Unknown | sample_type || Unknown | satellite_nodule_present || Unknown | second_gene_symbol || Unknown | secondhand_smoke_as_child || Unknown | site_of_resection_or_biopsy || Unknown | smoking_frequency || Unknown | supratentorial_localization || Unknown | synchronous_malignancy || Unknown | target_capture_kit || Unknown | test_analyte_type || Unknown | test_result || Unknown | test_units || Unknown | therapeutic_agents || Unknown | time_between_waking_and_first_smoke || Unknown | tissue_or_organ_of_origin || Unknown | tissue_type || Unknown | tobacco_smoking_status || Unknown | transglottic_extension || Unknown | treatment_anatomic_site || Unknown | treatment_effect || Unknown | treatment_effect_indicator || Unknown | treatment_frequency || Unknown | treatment_intent_type || Unknown | treatment_outcome || Unknown | treatment_type || Unknown | tumor_confined_to_organ_of_origin || Unknown | tumor_descriptor || Unknown | tumor_focality || Unknown | tumor_grade || Unknown | tumor_regression_grade || Unknown | type_of_smoke_exposure || Unknown | variant_origin || Unknown | variant_type || Unknown | vascular_invasion_present || Unknown | vascular_invasion_type || Unknown | viral_hepatitis_serologies || Unknown | vital_status || Unknown | who_cns_grade || Unknown | who_nte_grade || Unknown | wilms_tumor_histologic_subtype || Unknown | zygosity || unknown | gender || unknown | prior_malignancy || unknown | progression_or_recurrence || unknown | relationship_gender || unknown | relative_with_cancer_history || unknown | treatment_or_therapy || unknown | vital_status C102562 || C105721 || C106304 || C106317 || C106541 || C111073 || C112400 || C121007 || C123560 || C125738 || C126378 || C127768 || C127772 || C129439 || C13202 || C133427 || C133706 || C139007 || C140258 || C140259 || C140262 || C140266 || C141342 || C15256 || C15599 || C156421 || C156422 || C157110 || C157233 || C157410 || C157425 || C158874 || C159824 || C160720 || C160827 || C160996 || C16124 || C161320 || C16165 || C162221 || C164057 || C16457 || C16515 || C16564 || C166229 || C16687 || C17001 || C17049 || C17103 || C171253 || C17140 || C171435 || C173544 || C17357 || C173595 || C174459 || C175524 || C176287 || C176708 || C176985 || C177549 || C177550 || C177555 || C177556 || C177557 || C177558 || C177559 || C177561 || C177562 || C177564 || C177565 || C177566 || C177567 || C177568 || C177570 || C177571 || C177572 || C177573 || C177574 || C177575 || C177576 || C177578 || C177583 || C177585 || C177586 || C177587 || C177588 || C177589 || C177590 || C177591 || C177592 || C177593 || C177594 || C177595 || C177597 || C177598 || C177599 || C177600 || C177601 || C177603 || C177604 || C177605 || C177606 || C177607 || C177608 || C177609 || C177610 || C177611 || C177612 || C177613 || C177614 || C177616 || C177619 || C177620 || C177621 || C177622 || C177624 || C177625 || C177626 || C177627 || C177628 || C177630 || C177631 || C177632 || C177633 || C177634 || C177635 || C177636 || C177637 || C177638 || C177640 || C177641 || C178243 || C178276 || C178286 || C178287 || C178288 || C178289 || C18849 || C18919 || C1909 || C19232 || C19697 || C19770 || C19796 || C25185 || C25218 || C25294 || C25717 || C268 || C28013 || C28076 || C29878 || C2991 || C33027 || C35529 || C36037 || C36292 || C38032 || C4086 || C45824 || C45902 || C4809 || C49236 || C50995 || C53414 || C54398 || C55816 || C574 || C67415 || C70700 || C70713 || C70729 || C81229 || C81239 || C83280 || C83315 || C83393 || C85416 || C89081 || C90491 || C92808 || C93431 || C95149 || C99532 inpc_grade || ecog_performance_status || tumor_regression_grade || mitosis_karyorrhexis_index || menopause_status || igcccg_stage || premature_at_birth || child_pugh_classification || margin_status || figo_stage || alcohol_intensity || perineural_invasion_present || vascular_invasion_present || medulloblastoma_molecular_classification || chromosome || inrg_stage || mismatch_repair_mutation || iss_stage || enneking_msts_stage || enneking_msts_grade || enneking_msts_tumor_site || enneking_msts_metastasis || chemo_concurrent_to_radiation || hysterectomy_type || hormone_replacement_therapy_type || site_of_resection_or_biopsy || tissue_or_organ_of_origin || hpv_positive_type || first_symptom_prior_to_diagnosis || hormonal_contraceptive_use || tumor_focality || primary_site || lost_to_followup || lymphatic_invasion_present || satellite_nodule_present || transglottic_extension || prior_treatment || synchronous_malignancy || haart_treatment_indicator || metastasis_at_diagnosis || type_of_smoke_exposure || comorbidity || fragmentation_enzyme || ethnicity || tumor_descriptor || histone_family || ploidy || race || risk_factor || second_gene_symbol || environmental_tobacco_smoke_exposure || biospecimen_anatomic_site || variant_type || gender || gene_symbol || classification_of_tumor || peritoneal_fluid_cytological_status || cause_of_death_source || imaging_result || morphology || irs_group || irs_stage || ajcc_clinical_stage || ajcc_pathologic_stage || test_analyte_type || ann_arbor_clinical_stage || ann_arbor_pathologic_stage || ajcc_staging_system_edition || eln_risk_classification || comorbidity_method_of_diagnosis || inpc_histologic_group || who_cns_grade || who_nte_grade || wilms_tumor_histologic_subtype || progression_or_recurrence_anatomic_site || supratentorial_localization || distance_normal_to_tumor || radon_exposure || coal_dust_exposure || respirable_crystalline_silica_exposure || method_of_diagnosis || dysplasia_degree || target_capture_kit || ann_arbor_b_symptoms || ann_arbor_extranodal_involvement || bone_marrow_malignant_cells || burkitt_lymphoma_clinical_variant || columnar_mucosa_present || diagnosis_pathologically_confirmed || esophageal_columnar_metaplasia_present || gastric_esophageal_junction_involvement || barretts_esophagus_goblet_cells_present || goblet_cells_columnar_mucosa_present || hysterectomy_margins_involved || metaplasia_present || non_nodal_regional_disease || non_nodal_tumor_deposits || normal_tumor_genotype_snp_match || ovarian_surface_involvement || progression_or_recurrence || risk_factor_treatment || variant_origin || biospecimen_laterality || ajcc_clinical_m || ajcc_pathologic_m || ovarian_specimen_status || viral_hepatitis_serologies || instrument_model || ajcc_clinical_n || ajcc_pathologic_n || chipseq_antibody || chipseq_target || initial_disease_status || pregnant_at_diagnosis || histone_variant || primary_diagnosis || relationship_gender || cdc_hiv_risk_factors || metastasis_at_diagnosis_site || secondhand_smoke_as_child || smoking_frequency || time_between_waking_and_first_smoke || cog_liver_stage || cog_neuroblastoma_risk_group || cog_renal_stage || cog_rhabdomyosarcoma_risk_group || hepatitis_sustained_virological_response || ajcc_clinical_t || ajcc_pathologic_t || reflux_treatment_type || treatment_effect_indicator || progression_or_recurrence_type || esophageal_columnar_dysplasia_degree || relationship_primary_diagnosis || peripancreatic_lymph_nodes_positive || anaplasia_present || anaplasia_present_type || vascular_invasion_type || largest_extrapelvic_peritoneal_focus || history_of_tumor || prior_malignancy || treatment_outcome || therapeutic_agents || preservation_method || tissue_type || molecular_analysis_method || tobacco_smoking_status || laterality || treatment_type || laboratory_test || vital_status || antigen || karnofsky_performance_status || tumor_grade || relative_with_cancer_history || disease_type || lymph_node_involved_site || lymph_node_involvement || tumor_confined_to_organ_of_origin || test_result || treatment_effect || dysplasia_type || zygosity || alcohol_type || residual_disease || treatment_or_therapy || disease_response || composition || treatment_intent_type || asbestos_exposure || immunosuppressive_treatment_type || test_units || method_of_sample_procurement || sample_type || treatment_anatomic_site || alcohol_history || cause_of_death || exposure_duration || biospecimen_type || relationship_type || inss_stage || treatment_frequency || pregnancy_outcome || hormonal_contraceptive_type || procedures_performed || ishak_fibrosis_score || diabetes_treatment_type C C177537 GDC Value Terminology C18021 CCND1 Gene This gene plays a role in the regulation of mitotic events. CCND1 | gene_symbol || CCND1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18022 CDKN2A Gene This gene functions as a tumor suppressor and transcriptional regulator. CDKN2A | gene_symbol || CDKN2A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C181091 AQP1 Gene This gene plays a role in transmembrane transport of water. AQP1 | gene_symbol C173595 gene_symbol C C177537 GDC Value Terminology C18120 BRCA2 Gene This gene is involved in cell cycle control, DNA repair and the maintenance of genomic stability. It also plays a role in the proliferation of embryonic cells. BRCA2 | gene_symbol || BRCA2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18139 ERG Gene This gene plays a regulatory role in transcription, cellular maintenance and hematopoiesis. ERG | gene_symbol || ERG | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18173 TERT Gene This gene is involved in cell cycle regulation and telomere maintenance. TERT | gene_symbol || TERT | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18211 Protein Overexpression Synthesis of excess polypeptide within the cell. Overexpression is often due to the amplification or deregulation of the gene which encodes the gene product. Overexpressed | relationship_type C36292 test_result C C177537 GDC Value Terminology C18249 CDH1 Gene This gene plays a role in cell-cell adhesion and loss of function contributes to the progression of many carcinomas. CDH1 | gene_symbol || CDH1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18250 CDK4 Gene This gene is involved in G1 stage cell cycle progression. CDK4 | gene_symbol || CDK4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18251 EXT1 Gene This gene plays a role in heparin/heparin sulfate biosynthesis, axon guidance and biogenesis/cell organization. EXT1 | gene_symbol || EXT1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18252 EXT2 Gene This gene is involved in the heparin/heparin sulfate biosynthesis, cell organization/biogenesis and development of the cytoskeleton in chondrocytes. EXT2 | gene_symbol || EXT2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18253 STK11 Gene This gene plays a role in cell cycle regulation. It is also putatively involved in glucose production. STK11 | gene_symbol || STK11 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18254 MEN1 Gene This gene is involved in transcriptional regulation and has tumor suppressor activity. MEN1 | gene_symbol || MEN1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18255 PTCH1 Gene This gene is involved in tumor suppression and mutations in this gene have been associated with several cancers and cancer related diseases. PTCH1 | gene_symbol || PTCH1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18256 PTEN Gene This gene plays a role in signal transduction and apoptosis. It is also involved in the regulation of cell cycle progression. PTEN | gene_symbol || PTEN | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18257 RET Gene This gene plays an essential role in neural crest development, cellular growth and differentiation. Mutations in the gene are associated with a variety of neoplasias and carcinomas. RET | gene_symbol || RET | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18258 SMAD4 Gene This gene plays a role in signal transduction and transcriptional activation. It is also involved in suppression of angiogenesis. SMAD4 | gene_symbol || SMAD4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18259 TSC1 Gene This gene is involved in cell cycle regulation and the loss of cellular adhesion. TSC1 | gene_symbol || TSC1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18260 TSC2 Gene This gene plays a role in signal transduction and cell cycle control. It is involved in cell adhesion, differentiation, growth and migration. TSC2 | gene_symbol || TSC2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18261 VHL Gene This gene is involved in transcriptional repression and protein degradation. VHL | gene_symbol || VHL | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18262 WT1 Gene This gene plays a role in regulation of transcription. It is involved in the control of both cell differentiation and proliferation. WT1 | gene_symbol || WT1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18278 PDGFB Gene This gene is involved in cellular growth and proliferation. It is also plays a role in intercellular signaling. PDGFB | gene_symbol || PDGFB | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18301 TAL1 Gene This gene plays a role in regulation of transcription and cell organization. It is involved in both embryonic hematopoiesis and adult erythropoiesis. TAL1 | gene_symbol || TAL1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18312 ETV6 Gene This gene plays a regulatory role in transcription and in matrix metalloproteinase activity. ETV6 | gene_symbol || ETV6 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18321 FLI1 Gene This gene plays a role in transcriptional activation and has been implicated in the pathogenesis of neuroepithelioma. FLI1 | gene_symbol || FLI1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18322 EWSR1 Gene This gene may play a role in post-transcriptional regulation; however the function remains to be elucidated. Mutations in the gene result in Ewing sarcoma and other tumors. EWSR1 | gene_symbol || EWSR1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18325 MET Gene This gene plays a regulatory role in the modulation of cell-surface receptors and hepatocyte growth factor interactions. MET | gene_symbol || MET | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18337 PIM1 Gene This gene is involved in apoptosis, cell cycle regulation and signal transduction. PIM1 | gene_symbol || PIM1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18338 RAF1 Gene This gene is involved in cell growth, proliferation, differentiation and migration. It also plays a role in apoptosis. RAF1 | gene_symbol || RAF1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18345 MDM2 Gene This gene plays a role in several cellular processes related to cellular viability; including the cell cycle and apoptosis. MDM2 | gene_symbol || MDM2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18347 EIF3E Gene This gene is involved in the initiation and regulation of protein translation. EIF3E | gene_symbol || EIF3E | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18350 AKT1 Gene This gene is involved in signal transduction and negative regulation of apoptosis. It also plays a role in glucose transport, glycogen synthesis, protein synthesis and neuronal survival. AKT1 | gene_symbol || AKT1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18352 AKT2 Gene This gene plays a role in glucose homeostasis and the inhibition of apoptosis. AKT2 | gene_symbol || AKT2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18354 ARAF Gene This gene plays a role in signal transduction and the cellular response to mitogens. ARAF | gene_symbol || ARAF | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18356 RHOA Gene This gene plays a role in signal transduction. It is involved in several cellular functions including cell differentiation and cytoskeletal remodeling. RHOA | gene_symbol || RHOA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18360 BCL3 Gene This gene is involved in transcriptional co-activation and signal transduction. BCL3 | gene_symbol || BCL3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18363 BRAF Gene This gene is involved in cell organization/biogenesis and the inhibition of apoptosis. BRAF | gene_symbol || BRAF | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18364 CBL Gene This gene plays a role in signal transduction and the regulation of protein degradation. CBL | gene_symbol || CBL | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18365 VAV1 Gene This gene plays a role in signal transduction. It is involved in the development and activation of both B cells and T cells. VAV1 | gene_symbol || VAV1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18376 CCDC6 Gene This gene may play a role in tumor suppression. CCDC6 | gene_symbol || CCDC6 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18378 DDX6 Gene This gene plays a role in the translation of mRNA encoded by genes involved in cell proliferation and malignant transformation. DDX6 | gene_symbol || DDX6 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18381 NCOA4 Gene This gene is involved in the transcriptional activation of target genes. NCOA4 | gene_symbol || NCOA4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18384 EPHA3 Gene This gene is involved in receptor tyrosine kinase signal transduction and plays a role in lymphoid function and differentiation. EPHA3 | gene_symbol || EPHA3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18386 ERBB3 Gene This gene is involved in signal transduction pathways that result in cellular proliferation or differentiation. The gene has also been associated with numerous cancers. ERBB3 | gene_symbol || ERBB3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18388 ERBB4 Gene This gene is involved in neuronal development and plays a role in receptor tyrosine kinase signal transduction that regulates cellular proliferation and differentiation. ERBB4 | gene_symbol || ERBB4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18392 MECOM Gene This gene plays a role in transcriptional regulation, histone methylation and leukemogenesis. MECOM | gene_symbol || MECOM | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18394 SMARCB1 Gene This gene plays a role in chromatin remodeling and regulation of transcription. SMARCB1 | gene_symbol || SMARCB1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18397 FAT1 Gene This gene is involved in both cellular polarization and cell-cell adhesion. FAT1 | gene_symbol || FAT1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18399 ROS1 Gene This gene plays a role in receptor tyrosine phosphorylation signal transduction, and is thought to play a role in cellular growth or differentiation, but an exact function has not been substantiated. ROS1 | gene_symbol || ROS1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18404 NFKB2 Gene This gene plays a role in transcriptional regulation, signal transduction and inflammatory responses. NFKB2 | gene_symbol || NFKB2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18405 MYCN Gene This gene is involved in transcriptional regulation and amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. MYCN | gene_symbol || MYCN | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18407 MYCL Gene This gene is involved in transcriptional regulation and is frequently amplified in small-cell lung cancer. MYCL | gene_symbol || MYCL | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18411 MPL Gene This gene plays a regulatory role in megakaryocytopoiesis and platelet formation. MPL | gene_symbol || MPL | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18417 MAF Gene This gene plays a role in transcriptional regulation and cellular differentiation. MAF | gene_symbol || MAF | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18430 IRF4 Gene This gene is involved in the regulation of B-cell differentiation and proliferation. It also plays a role in mediating the proliferation of mitogen-stimulated T cells. IRF4 | gene_symbol || IRF4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18451 ABL2 Gene This gene plays a role in signal transduction. ABL2 | gene_symbol || ABL2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18455 BCR Gene This gene plays a role in signal transduction. BCR | gene_symbol || BCR | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18481 MSH2 Gene This gene plays a role in DNA mismatch repair mutations in the gene result in hereditary nonpolyposis colorectal cancer-1. MSH2 | gene_symbol || MSH2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18482 MLH1 Gene This gene plays a role in DNA mismatch repair. MLH1 | gene_symbol || MLH1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18504 SMAD3 Gene This gene is involved in signal transduction and apoptosis. It also plays a role in the regulation of both steroid synthesis and T-cell response. SMAD3 | gene_symbol || SMAD3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18516 CSF1R Gene This gene is essential for the regulation of the production, differentiation, and function of macrophages. CSF1R | gene_symbol || CSF1R | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18524 FHIT Gene This gene is involved in nucleotide metabolism and cell cycle control. FHIT | gene_symbol || FHIT | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18541 LCK Gene This gene is involved in signal transduction and the development/function of T cells. LCK | gene_symbol || LCK | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18551 NTRK1 Gene This gene is involved in cellular differentiation and neurotrophic functions. NTRK1 | gene_symbol || NTRK1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18576 MAX Gene This gene is involved in transcriptional regulation and plays a role in the mediation of DNA-protein interactions. MAX | gene_symbol || MAX | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18579 RUNX1 Gene This gene plays a role in transcriptional regulation and cytogenetic aberrations are associated with several leukemias. RUNX1 | gene_symbol || RUNX1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18583 ATM Gene This gene is involved in apoptosis, DNA repair and cell cycle regulation. ATM | gene_symbol || ATM | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18584 CBFB Gene This gene is involved in hematopoiesis and osteogenesis. CBFB | gene_symbol || CBFB | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18585 KMT2A Gene This gene is involved in transcriptional regulation and alterations in the gene are associated with acute lymphoblastic leukemia. KMT2A | gene_symbol || KMT2A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18590 PMS1 Gene This gene is involved in mismatch repair and mutations in the gene result in hereditary non-polyposis colon cancer 3. MLH2 | gene_symbol || MLH2 | second_gene_symbol || PMS1 | gene_symbol || PMS1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18591 PMS2 Gene This gene is involved in mismatch repair and mutations in the gene result in hereditary non-polyposis colon cancer 4. PMS2 | gene_symbol || PMS2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18592 TGFBR2 Gene This gene plays a role in cellular proliferation and mitogenic responses. TGFBR2 | gene_symbol || TGFBR2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18608 TLX1 Gene This gene plays a role in transcriptional regulation and organogenesis. Translocations in the gene are associated with acute T-cell leukemia. TLX1 | gene_symbol || TLX1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C18609 KIT Gene This gene plays a role in cellular hematopoiesis and differentiations. Mutations in the gene are associated with several diseases, including acute myelogenous leukemia, gastrointestinal tumors, and mast cell disease. KIT | gene_symbol || KIT | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C19195 MSH6 Gene This gene is involved in mismatch repair and plays a role in several cancers. MSH6 | gene_symbol || MSH6 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C19531 JUN Gene This gene plays a critical role in transcriptional regulation and cellular growth. JUN | gene_symbol || JUN | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C19874 SMARCE1 Gene This gene is involved in chromatin remodeling and regulation of transcription. SMARCE1 | gene_symbol || SMARCE1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C19875 SMARCD1 Gene This gene plays a role in chromatin remodeling and regulation of transcription. SMARCD1 | gene_symbol || SMARCD1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C19878 SMARCA4 Gene This gene plays a role in chromatin remodeling, cell cycle control and regulation of transcription. SMARCA4 | gene_symbol || SMARCA4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C19917 SRC Gene This gene is involved in apoptosis, hormonogenesis, focal adhesion and the formation of intercellular junctions. SRC | gene_symbol || SRC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C19929 FGFR1 Gene This gene plays a role in mitogenesis and differentiation. FGFR1 | gene_symbol || FGFR1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C19931 FGFR2 Gene This gene plays a role in mitogenesis and differentiation and mutations in the gene are associated with craniosynostotic syndromes and bone malformations. FGFR2 | gene_symbol || FGFR2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C19969 AXIN1 Gene This gene plays a role in signal transduction and is involved in development. AXIN1 | gene_symbol || AXIN1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20060 CDKN1B Gene This gene is involved in cell cycle regulation and cyclin regulation. CDKN1B | gene_symbol || CDKN1B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20070 WRN Gene This gene is involved in DNA repair and the unwinding of DNA. WRN | gene_symbol || WRN | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20174 NRG1 Gene This gene plays a role in cellular differentiation, growth and proliferation. NRG1 | gene_symbol || NRG1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20352 BIRC6 Gene This gene regulates the apoptotic program via signal transduction in the ubiquitination pathway. BIRC6 | gene_symbol || BIRC6 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20356 BIRC3 Gene This anti-apoptotic gene regulates apoptotic activity. BIRC3 gene promotes tumor cell survival. BIRC3 | gene_symbol || BIRC3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20361 XPA Gene This gene facilitates DNA binding in repair processes and is associated with the disease xeroderma pigmentosum complementation group A. XPA | gene_symbol || XPA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20555 ERCC2 Gene This gene is involved in nucleotide excision repair and corrects sensitivity to UV radiation and defective nucleotide excision repair in xeroderma pigmentosum cells of complementation group D. ERCC2 | gene_symbol || ERCC2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20556 ERCC3 Gene This gene is involved in DNA excision repair and transcription. ERCC3 | gene_symbol || ERCC3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20557 ERCC5 Gene This gene plays a role in the nucleotide base excision repair of UV-induced DNA damage and mutations of the gene cause Cockayne syndrome. ERCC5 | gene_symbol || ERCC5 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20558 ERCC4 Gene This gene is involved in nucleotide excision repair and is involved in the correction of defective nucleotide excision repair in xeroderma pigmentosum cells of complementation group F. ERCC4 | gene_symbol || ERCC4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20560 ATR Gene This gene is involved in cell cycle checkpoints and DNA recombination. ATR | gene_symbol || ATR | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20576 HMGA1 Gene This gene plays a role in a number of cellular processes including apoptosis, chromatin organization and transcriptional regulation. HMGA1 | gene_symbol || HMGA1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20577 HMGA2 Gene This gene is involved in chromatin organization and regulation of gene transcription. It also plays a role in development. HMGA2 | gene_symbol || HMGA2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20676 PSIP1 Gene This gene is involved in regulation of transcription. It also plays a role in mediation of pre-mRNA splicing. PSIP1 | gene_symbol || PSIP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20695 NCOA1 Gene This gene plays a role in regulation of transcription. NCOA1 | gene_symbol || NCOA1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20697 NCOA2 Gene This gene is involved in regulation of transcription. It also plays a role in myogenic differentiation. NCOA2 | gene_symbol || NCOA2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20715 BARD1 Gene This gene plays a role in cellular response and is susceptible to oncogenic mutations in breast and ovarian cancers. BARD1 | gene_symbol || BARD1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20743 FGFR4 Gene This gene plays a role in mitogenesis and differentiation. FGFR4 | gene_symbol || FGFR4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20763 AXIN2 Gene This gene is involved in signal transduction and plays a role in development. AXIN2 | gene_symbol || AXIN2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20766 BAP1 Gene This gene is involved in cellular growth regulation and is purported to have tumor suppression activity. BAP1 | gene_symbol || BAP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20786 FBXW7 Gene This gene is involved in ubiquitin-dependent proteolysis and regulation of the G1-S cell cycle checkpoint. FBXW7 | gene_symbol || FBXW7 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20805 BLM Gene This gene plays a role in DNA unwinding and recombination-mediated telomere lengthening. BLM | gene_symbol || BLM | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20820 NUP98 Gene This gene plays a role in transport and is frequently overexpressed in prostate cancers. NUP98 | gene_symbol || NUP98 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20899 ELF3 Gene This gene is involved in the regulation of both transcription and epithelial cell differentiation. It also plays a role in angiogenesis. ELF3 | gene_symbol || ELF3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20937 AKT3 Gene This gene is involved in signal transduction and the inhibition of apoptosis. AKT3 | gene_symbol || AKT3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C20987 CTNNB1 Gene This gene is involved in signal transduction and regulation of transcription. CTNNB1 | gene_symbol || CTNNB1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21091 TNC Gene This gene is involved in cell adhesion, differentiation and proliferation. TNC | gene_symbol || TNC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21167 CHGA Gene This gene plays a role in the modulation of the neuroendocrine system. CHGA | gene_symbol || CHGA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21178 NBN Gene This gene plays a role in DNA repair and cell cycle checkpoints. NBN | gene_symbol || NBN | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21185 NPM1 Gene This gene is involved in the regulation of ribosomal assembly. NPM1 | gene_symbol || NPM1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21220 PIK3CA Gene This gene is involved in apoptosis, cell growth and angiogenesis. PIK3CA | gene_symbol || PIK3CA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21222 MAP2K1 Gene This gene plays a role in signal transduction and regulation of transcription. It is also involved in cell differentiation, growth and proliferation. MAP2K1 | gene_symbol || MAP2K1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21227 MAPK1 Gene This gene plays a role in signal transduction and positive regulation of the cell cycle. MAPK1 | gene_symbol || MAPK1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21232 MGMT Gene This gene is involved in DNA repair. MGMT | gene_symbol || MGMT | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21267 ACVR1 Gene This gene plays a role in the transforming growth factor-beta signal transduction pathway through serine/threonine specificity. ACVR1 | gene_symbol || ACVR1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21271 ACVR2A Gene This gene plays a role in the transforming growth factor-beta signal transduction pathway through constitutive kinase activity. ACVR2A | gene_symbol || ACVR2A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21291 CD28 Gene This gene plays several roles in cellular functions specific to the T-cell. CD28 | gene_symbol || CD28 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21294 LCP1 Gene This gene plays a role in cytoskeletal remodeling. LCP1 | gene_symbol || LCP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21305 AKAP9 Gene This gene plays a role in signal transduction and modulates synaptic transmission. AKAP9 | gene_symbol || AKAP9 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21320 RHOH Gene This gene plays a role in signal transduction in hematopoietic cells. RHOH | gene_symbol || RHOH | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21327 EZH2 Gene This gene plays a role in chromatin remodeling and transcriptional regulation. EZH2 | gene_symbol || EZH2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21353 BMP5 Gene This gene plays a role in the regulation of mesenchymal differentiation. It is involved in cartilage and bone formation. BMP5 | gene_symbol || BMP5 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21366 BMPR1A Gene This gene plays a role in the bone morphogenetic protein signaling pathway. BMPR1A | gene_symbol || BMPR1A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21385 AFF4 Gene This gene plays a regulatory role in transcription and is involved in male germ cell differentiation. AFF4 | gene_symbol || AFF4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21412 CCNE1 Gene This gene regulates the G1/S phase of the cell cycle by cyclin expression. CCNE1 | gene_symbol || CCNE1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21416 NSD2 Gene This gene plays a role in histone-lysine methylation. NSD2 | gene_symbol || NSD2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21555 FAS Gene This gene is involved in the mediation of cellular surface receptors and apoptotic signals. FAS | gene_symbol || FAS | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21568 CD209 Gene This gene plays a role in the regulation of host defense responses and mediates pathogen-binding properties. CD209 | gene_symbol || CD209 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21571 RARA Gene This gene plays a role in transcription and retinoic acid receptor signal transduction. RARA | gene_symbol || RARA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C21589 CBLB Gene This gene plays a role in the regulation of T cell activation. CBLB | gene_symbol || CBLB | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24259 BCL10 Gene This gene is involved in the promotion of apoptosis. BCL10 | gene_symbol || BCL10 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24260 BCL6 Gene This gene is involved in transcriptional repression and plays a role in the modulation of B-cell responses. BCL6 | gene_symbol || BCL6 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24261 BCL7A Gene This gene may play a role in signal transduction. BCL7A | gene_symbol || BCL7A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24262 BCL9 Gene This gene plays a role in signal transduction and is involved in development. BCL9 | gene_symbol || BCL9 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24288 CDKN2C Gene This gene is involved in cell cycle inhibition and regulation. CDKN2C | gene_symbol || CDKN2C | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24292 CDX2 Gene This gene plays a role in transcriptional initiation, embryonic axial elongation and patterning. CDX2 | gene_symbol || CDX2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24308 COX6C Gene This gene is involved in mitochondrial respiration. COX6C | gene_symbol || COX6C | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24313 CSF3R Gene This gene plays an inhibitory role in cell survival and proliferation. CSF3R | gene_symbol || CSF3R | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24323 CUL3 Gene This gene plays a role in protein degradation and cell cycle arrest. CUL3 | gene_symbol || CUL3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24327 CXCR4 Gene This gene is involved in the mediation of viral entry into cells and cellular migration and chemotaxis. CXCR4 | gene_symbol || CXCR4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24330 DAXX Gene This gene plays a role in signal transduction, regulation of transcription and enhancement of apoptosis. DAXX | gene_symbol || DAXX | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24333 DDR2 Gene This gene plays a role in extracellular matrix communication processes and receptor-mediated signal transduction. DDR2 | gene_symbol || DDR2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24339 DEK Gene This gene is involved in RNA processing and regulation of chromatin organization. DEK | gene_symbol || DEK | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24369 EPS15 Gene This gene plays a role in signal transduction and cell proliferation. EPS15 | gene_symbol || EPS15 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24377 ETV1 Gene This gene is involved in transcriptional activation and spinal cord development. ETV1 | gene_symbol || ETV1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24378 ETV4 Gene This gene plays a regulatory role in transcription and in matrix metalloproteinase activity. ETV4 | gene_symbol || ETV4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24385 FANCG Gene This gene is involved in the maintenance of genomic integrity and nuclear signal transduction. Allelic variants of the gene are involved in Fanconi syndrome. FANCG | gene_symbol || FANCG | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24393 FGFR3 Gene This gene plays a role in bone development and maintenance and mutations in the gene are associated with craniosynostosis and several types of skeletal dysplasia. FGFR3 | gene_symbol || FGFR3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24397 RSPO3 Gene This gene is thought to be involved in transport; however, a function has yet to be elucidated. RSPO3 | gene_symbol || RSPO3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24399 FLT3 Gene This gene plays a role in hematopoiesis and may function as a growth factor receptor. FLT3 | gene_symbol || FLT3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24400 FLT4 Gene This gene plays an essential role in the development of embryonic cardiovasculature and lymphatic vessel formation. FLT4 | gene_symbol || FLT4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24401 CEP43 Gene This gene is involved in the regulation of cell shape, polarity and motility. FGFR1OP | gene_symbol || FGFR1OP | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24402 FOXO1 Gene This gene is involved in transcriptional regulation and may play a role in myogenic growth and differentiation. FOXO1 | gene_symbol || FOXO1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24408 FSTL3 Gene This gene plays a role in a variety of processes including transcription. FSTL3 | gene_symbol || FSTL3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24410 KDSR Gene This gene plays a role in glycosphingolipid metabolism. KDSR | gene_symbol || KDSR | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24432 GLI1 Gene This gene plays a regulatory role in transcription and embryonic development. GLI1 | gene_symbol || GLI1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24474 HOXA9 Gene This gene plays a role in transcriptional regulation, morphogenesis and differentiation. HOXA9 | gene_symbol || HOXA9 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24498 IL2 Gene This gene is involved in growth and lymphokine regulation. IL2 | gene_symbol || IL2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24505 IL6ST Gene This gene plays a role in signal transduction and is putatively involved in embryonic development. IL6ST | gene_symbol || IL6ST | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24506 IL7R Gene This gene is involved in the regulation of lymphopoiesis. IL7R | gene_symbol || IL7R | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24524 IRS4 Gene This gene plays a role in signal transduction and ligand binding. IRS4 | gene_symbol || IRS4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24526 ITK Gene This gene is involved in the differentiation and proliferation of T cells. ITK | gene_symbol || ITK | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24528 JAK1 Gene This gene plays a role in signal transduction. JAK1 | gene_symbol || JAK1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24529 JAK2 Gene This gene is involved in erythropoiesis and signal transduction. JAK2 | gene_symbol || JAK2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24530 JAK3 Gene This gene plays a role in signal transduction. JAK3 | gene_symbol || JAK3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24532 KDR Gene This gene plays a role in angiogenesis and vascular regulation. KDR | gene_symbol || KDR | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24538 AFF3 Gene This gene is involved in transcriptional activation and is purported to play roles in lymphoid development and oncogenesis. AFF3 | gene_symbol || AFF3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24552 LIFR Gene This gene plays a critical role in cell fate and proliferation in both embryonic and adult cells. LIFR | gene_symbol || LIFR | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24564 LYL1 Gene This gene plays a role in transcriptional regulation and is involved in the pathogenesis of acute lymphoblastic leukemia. LYL1 | gene_symbol || LYL1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24566 SMAD2 Gene This gene plays a role in signal transduction and repression of transcription. SMAD2 | gene_symbol || SMAD2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24572 MAP3K1 Gene This gene plays a role in mediating cellular responses to growth factors, metabolic stimuli and mitogens. MAP3K1 | gene_symbol || MAP3K1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24600 KMT2D Gene This gene plays a role in co-activation of gene expression. KMT2D | gene_symbol || KMT2D | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24601 MLLT1 Gene This gene is involved in transcriptional regulation and translocations in the gene are associated with acute leukemia. MLLT1 | gene_symbol || MLLT1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24602 AFF1 Gene This gene is involved in transcriptional regulation and translocations in the gene are associated with acute leukemia. AFF1 | gene_symbol || AFF1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24603 MLLT3 Gene This gene plays a role in transcriptional regulation and translocations in the gene are associated with leukemia. MLLT3 | gene_symbol || MLLT3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24604 AFDN Gene This gene is involved in cell adhesion and cytoskeletal modeling. MLLT4 | gene_symbol || MLLT4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24605 MLLT6 Gene This gene is involved in transcriptional regulation and aberrations in the gene are associated with acute leukemias due to chromosomal translocations. MLLT6 | gene_symbol || MLLT6 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24606 FOXO4 Gene This gene plays a role in smooth muscle cell differentiation, cellular growth, cell cycle regulation and tumor suppression. FOXO4 | gene_symbol || FOXO4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24617 MTCP1 Gene This gene plays a role in the proliferation of T cells and is involved in cell cycle regulation. MTCP1 | gene_symbol || MTCP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24625 NDRG1 Gene This gene plays a role in cellular stress responses. It is also involved in both cell growth and differentiation. NDRG1 | gene_symbol || NDRG1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24636 NOTCH1 Gene This gene is involved in intercellular signal transduction that plays a key role in development. NOTCH1 | gene_symbol || NOTCH1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24647 NTRK3 Gene This gene plays a role in neuronal development and cellular differentiation. Mutations in the gene are associated with medulloblastomas, secretory breast carcinomas and other cancers. NTRK3 | gene_symbol || NTRK3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24648 NUMA1 Gene This gene plays an essential role in normal mitosis. It is also involved in cell organization/biogenesis. NUMA1 | gene_symbol || NUMA1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24649 NUP214 Gene This gene plays a critical role in nuclear transport and docking regulation. Alterations in the gene have been associated with several cancers and leukemias. NUP214 | gene_symbol || NUP214 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24658 PAX3 Gene This gene plays a role in the transcriptional activation of target genes. It is involved in melanogenesis, neurogenesis and skeletal muscle development. PAX3 | gene_symbol || PAX3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24659 PAX5 Gene This gene is involved in the transcriptional regulation of target genes. It plays a role in B-cell differentiation, neural development and spermatogenesis. PAX5 | gene_symbol || PAX5 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24660 PAX7 Gene This gene plays a role in the transcriptional regulation of target genes. It is involved in pattern formation during embryogenesis. PAX7 | gene_symbol || PAX7 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24666 PDGFRA Gene This gene plays a role in mitogenic activities affecting mesenchymal cells and is involved in receptor tyrosine kinase signal transduction. PDGFRA | gene_symbol || PDGFRA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24667 PDGFRB Gene This gene plays a role in mitogenic activities affecting mesenchymal cells and a translocation in the gene results in chronic myelomonocytic leukemia. PDGFRB | gene_symbol || PDGFRB | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24672 PIK3CB Gene This gene is involved in apoptosis, cell growth and angiogenesis. PIK3CB | gene_symbol || PIK3CB | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24686 PML Gene This gene plays a role in tumor suppression and is involved in the regulation of p53 in response to oncogenic signal transduction. PML | gene_symbol || PML | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24689 PPARG Gene This gene plays a regulatory role in adipocyte differentiation. PPARG | gene_symbol || PPARG | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24692 PRDM1 Gene This gene is involved in repression of transcription. It plays a role in the formation of pre-plasma memory B cells and immunoglobulin-secreting plasma cells. PRDM1 | gene_symbol || PRDM1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24701 PTK6 Gene This gene plays a role in signal transduction. PTK6 | gene_symbol || PTK6 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24708 PTPN6 Gene This gene plays a role in the regulation of multiple signaling pathways in hematopoietic cells. PTPN6 | gene_symbol || PTPN6 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24710 SIRPA Gene This gene is involved in cellular signal transduction and tyrosine kinase-coupled signaling processes. SIRPA | gene_symbol || SIRPA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24711 PTPRC Gene This gene plays a role in suppression of cytokine receptor signaling and the regulation of signal transduction in lymphocytes. PTPRC | gene_symbol || PTPRC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24716 PTPRT Gene This gene plays a role in the control of motor axon guidance. PTPRT | gene_symbol || PTPRT | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24721 RALGDS Gene This gene plays a role in signal transduction and cytoskeletal remodeling. It is also involved in regulation of cell growth. RALGDS | gene_symbol || RALGDS | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24733 TRIM27 Gene This gene is involved in the differentiation of male germ cells. TRIM27 | gene_symbol || TRIM27 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24748 RPL10 Gene This gene plays a role in protein biosynthesis. It is also involved in signal transduction. RPL10 | gene_symbol || RPL10 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24801 SET Gene This gene is involved in apoptosis, biogenesis, DNA replication and nuclear organization. SET | gene_symbol || SET | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24804 SFRP4 Gene This gene plays a role in signal transduction, apoptosis and cell proliferation. SFRP4 | gene_symbol || SFRP4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24817 SMO Gene This gene plays a role in G protein-coupled receptor signal transduction and sonic hedgehog pathway activation. SMO | gene_symbol || SMO | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24824 ABI1 Gene This gene plays a role in signal transduction and negative regulation of cell proliferation. ABI1 | gene_symbol || ABI1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24833 STAT3 Gene This gene plays a role in signal transduction and activation of transcription. It is involved in regulation of both apoptosis and cell growth. STAT3 | gene_symbol || STAT3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24835 STAT6 Gene This gene plays a role in signal transduction and activation of transcription. STAT6 | gene_symbol || STAT6 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24843 TAL2 Gene This gene is involved in transcriptional regulation. It plays a role in T-cell acute lymphocytic leukemia. TAL2 | gene_symbol || TAL2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24844 WWTR1 Gene This gene is involved in regulation of transcription. It is involved in fetal/neonatal cardiac and muscle development. WWTR1 | gene_symbol || WWTR1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24846 TCF3 Gene This gene plays a role in regulation of transcription. It is involved in the control of tissue-specific cell fate during embryogenesis. TCF3 | gene_symbol || TCF3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24847 TCF7L2 Gene This gene plays a role in signal transduction and regulation of transcription. TCF7L2 | gene_symbol || TCF7L2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24850 TEC Gene This gene is involved in signal transduction and regulation of immune function. TEC | gene_symbol || TEC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24854 TFE3 Gene This gene plays a role in transcriptional activation. It is involved in melanogenesis. TFE3 | gene_symbol || TFE3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24871 TMPRSS2 Gene This gene plays a role in the activation of pathway signaling. TMPRSS2 | gene_symbol || TMPRSS2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24880 TRRAP Gene This gene is involved in DNA repair and regulation of mitosis. TRRAP | gene_symbol || TRRAP | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24881 TSHR Gene This gene plays an important role in the regulation of thyroid cell metabolism. TSHR | gene_symbol || TSHR | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24892 USP6 Gene This gene is involved in the regulation of cellular ubiquitination. It also plays a role in promoting the recycling of endocytic vesicles to the plasma membrane. USP6 | gene_symbol || USP6 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C24893 USP8 Gene This gene plays a role in ubiquitin-dependent proteolysis and cell proliferation. USP8 | gene_symbol || USP8 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C25228 Right Being or located on or directed toward the side of the body to the east when facing north. Right | biospecimen_laterality || Right | laterality || Right | undescended_testis_corrected_laterality || Right | undescended_testis_history_laterality C177605 || C181723 || C182102 || C25185 biospecimen_laterality || undescended_testis_corrected_laterality || undescended_testis_history_laterality || laterality C C177537 GDC Value Terminology C25229 Left Being or located on or directed toward the side of the body to the west when facing north. Left | biospecimen_laterality || Left | laterality || Left | undescended_testis_corrected_laterality || Left | undescended_testis_history_laterality C177605 || C181723 || C182102 || C25185 biospecimen_laterality || undescended_testis_corrected_laterality || undescended_testis_history_laterality || laterality C C177537 GDC Value Terminology C25785 KRAS Gene This gene is involved in signal transduction and apoptosis. KRAS | gene_symbol || KRAS | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C25786 NRAS Gene This gene plays a role in signal transduction and cell cycle regulation. NRAS | gene_symbol || NRAS | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C25955 DROSHA Gene This gene plays a role in the processing of microRNA in the nucleus. DROSHA | gene_symbol || DROSHA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C25956 DICER1 Gene This gene is involved in the RNA interference pathway. DICER1 | gene_symbol || DICER1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C26337 PTPN11 Gene This gene plays a role in the regulation of cell signaling. It is involved in cell migration, metabolic control, mitogenic activation and gene transcription. PTPN11 | gene_symbol || PTPN11 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C26372 HIF1A Gene This gene plays a role in cardiovascular development and systemic oxygen homeostasis. HIF1A | gene_symbol || HIF1A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C26373 ARNT Gene This gene is involved in xenobiotic metabolism and receptor-ligand mediated interactions. ARNT | gene_symbol || ARNT | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C26418 T-Cell Receptor Beta Locus This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the beta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several D and J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Chromosomal abnormalities involving the T-cell receptor beta locus have been associated with T-cell lymphomas. (from LocusLink) TRB | gene_symbol || TRB | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C26419 T-Cell Receptor Alpha Locus This region represents the germline organization of the T cell receptor alpha locus. The alpha locus includes V (variable), J (joining), and C (constant) segments. During T cell development, the alpha chain is synthesized by a recombination event at the DNA level joining a V segment with a J segment. The C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. (from LocusLink) TRA | gene_symbol || TRA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C26420 T-Cell Receptor Delta Locus This region represents the germline organization of the T cell receptordelta locus. The delta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several D and J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. (from LocusLink) TRD | gene_symbol || TRD | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C26422 Immunoglobulin Heavy Locus This region represents the germline organization of the immunoglobulin heavy chain locus. The locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a D segment with a J segment; a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several D and J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. (from LocusLink) IGH | gene_symbol || IGH | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C26423 Immunoglobulin Lambda Locus This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. (from LocusLink) IGL | gene_symbol || IGL | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C26425 Immunoglobulin Kappa Locus This region represents the germline organization of the kappa light chain locus. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. (from LocusLink) IGK | gene_symbol || IGK | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C26492 RECQL4 Gene This gene is involved in the initiation of DNA replication and sister-chromatid cohesion. RECQL4 | gene_symbol || RECQL4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C26536 SYK Gene This gene plays a role in receptor tyrosine phosphorylation signal transduction, phagocytosis, endothelial cell growth and proliferation. SYK | gene_symbol || SYK | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C26568 CREBBP Gene This gene plays a role in transcriptional regulation and in NF-kappa B signal transduction. CREBBP | gene_symbol || CREBBP | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C26569 EP300 Gene This gene plays a role in DNA repair and regulation of transcription. EP300 | gene_symbol || EP300 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C26584 KLK2 Gene This gene plays a role in proteolysis. KLK2 | gene_symbol || KLK2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C26591 TOP1 Gene This gene is involved in the regulation of both DNA topology and transcription. TOP1 | gene_symbol || TOP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C26623 CASP8 Gene This gene is involved in apoptosis, immune cell homeostasis, lymphocyte activation and immunoprotection. CASP8 | gene_symbol || CASP8 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C28519 FOXO3 Gene This gene is involved in transcriptional regulation and apoptosis. FOXO3 | gene_symbol || FOXO3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C28539 AR Gene This gene plays a role in the transcriptional activation of androgen responsive genes. AR | gene_symbol || AR | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C28569 MYB Gene This gene plays a role in hematopoietic cell proliferation and development. MYB | gene_symbol || MYB | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C28570 RUNX1T1 Gene This gene plays a role in transcriptional regulation and hematopoiesis. RUNX1T1 | gene_symbol || RUNX1T1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C28575 GATA1 Gene This gene is involved in erythropoiesis and transcriptional activation. GATA1 | gene_symbol || GATA1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C28585 HLA-A Gene This gene is involved in immune responses and histocompatibility processes. HLA-A | gene_symbol || HLA-A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C28633 NCOR2 Gene This gene plays a role in repression of transcription. It is also involved in chromatin remodeling. NCOR2 | gene_symbol || NCOR2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C28635 ZBTB16 Gene This gene plays a role in apoptosis and regulation of transcription. It is also involved in cell organization/biogenesis and megakaryocytic development. ZBTB16 | gene_symbol || ZBTB16 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C28640 NCOR1 Gene This gene is involved in chromatin remodeling and repression of transcription. NCOR1 | gene_symbol || NCOR1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C28656 PGR Gene This gene plays a role in the signal transduction processes that are involved in pregnancy. PGR | gene_symbol || PGR | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C28667 STAT5B Gene This gene is involved in signal transduction and activation of transcription. It plays a role in the immune response via stimulation of T-cell proliferation. STAT5B | gene_symbol || STAT5B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C29949 COL1A1 Gene This gene plays an important structural role in cartilage and mutations in the gene are associated with osteogenesis imperfecta. COL1A1 | gene_symbol || COL1A1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C29957 MYH11 Gene This gene plays a regulatory role in muscle contraction and the required ATP hydrolysis. MYH11 | gene_symbol || MYH11 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C35571 Progressive Disease A clinical, pathologic, and/or molecular finding indicating that the course of a disease is worsening in terms of extent or severity. PD-Progressive Disease | best_overall_response || PD-Progressive Disease | disease_response || Progressive Disease | initial_disease_status || Progressive Disease | treatment_outcome C177616 || C18919 || C50995 || C94536 initial_disease_status || treatment_outcome || disease_response || best_overall_response C C177537 GDC Value Terminology C38184 ALK Gene This gene is involved in brain development and neuronal specificity. ALK | gene_symbol || ALK | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C38316 GNAQ Gene This gene plays a role in signal transduction and is involved in calcium signaling. GNAQ | gene_symbol || GNAQ | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C38317 GNAS Gene This gene plays a role in signal transduction and is associated with pituitary tumors. GNAS | gene_symbol || GNAS | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C38349 ESR1 Gene This gene is involved in ligand-activated transcriptional activity. ESR1 | gene_symbol || ESR1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C38396 NFKBIE Gene This gene plays a role in signal transduction and regulation of transcription. It is involved in the immune response. NFKBIE | gene_symbol || NFKBIE | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C38401 NFIB Gene This gene plays a role in transcriptional regulation and mediates DNA-binding interactions. NFIB | gene_symbol || NFIB | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C38409 PRKACA Gene This gene is involved in the regulation of diverse cell processes including cell growth, proliferation, differentiation and motility. PRKACA | gene_symbol || PRKACA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C38517 TFRC Gene This gene plays a regulatory role in receptor-mediated endocytosis and iron metabolism. TFRC | gene_symbol || TFRC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C38536 CREB1 Gene This gene is involved in transcriptional regulation and its activity is modulated in response to hormonal stimulation from the cAMP pathway. CREB1 | gene_symbol || CREB1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C38554 FCGR2B Gene This gene plays a role in the inhibition of immune functions and cellular proliferation. FCGR2B | gene_symbol || FCGR2B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C38896 B-Lymphocyte Antigen CD20 B-lymphocyte antigen CD20 (297 aa, ~33 kDa) is encoded by the human MS4A1 gene. This protein plays a role in both the activation and proliferation of B-cells. CD20 | antigen || FMC-7 | antigen C268 antigen C C177537 GDC Value Terminology C38928 MTOR Gene This gene plays a role in apoptosis, cell growth, differentiation and proliferation. MTOR | gene_symbol || MTOR | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C38939 MUC1 Gene This gene plays a role in cellular signal transduction and is used as a biomarker for breast cancer. MUC1 | gene_symbol || MUC1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C39596 CCND2 Gene This gene is involved in the regulation of the G1/S phase of the cell cycle. CCND2 | gene_symbol || CCND2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C39597 PRKCB Gene This gene is involved in diverse cell processes such as apoptosis, B cell activation and endothelial cell proliferation. PRKCB | gene_symbol || PRKCB | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C39598 CEBPA Gene This gene plays a role in body weight homeostasis and cellular proliferation. Mutations in the gene are associated with acute myeloid leukemia. CEBPA | gene_symbol || CEBPA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C40965 CHEK2 Gene This gene plays a role in cell survival and the negative regulation of cell growth. CHEK2 | gene_symbol || CHEK2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C43234 Not Reported Not provided or available. Not Reported | adrenal_hormone || Not Reported | ajcc_clinical_m || Not Reported | ajcc_clinical_n || Not Reported | ajcc_clinical_stage || Not Reported | ajcc_clinical_t || Not Reported | ajcc_pathologic_m || Not Reported | ajcc_pathologic_n || Not Reported | ajcc_pathologic_stage || Not Reported | ajcc_pathologic_t || Not Reported | ajcc_staging_system_edition || Not Reported | alcohol_history || Not Reported | alcohol_intensity || Not Reported | alcohol_type || Not Reported | anaplasia_present || Not Reported | anaplasia_present_type || Not Reported | ann_arbor_b_symptoms || Not Reported | ann_arbor_clinical_stage || Not Reported | ann_arbor_extranodal_involvement || Not Reported | ann_arbor_pathologic_stage || Not Reported | antigen || Not Reported | asbestos_exposure || Not Reported | barretts_esophagus_goblet_cells_present || Not Reported | biospecimen_anatomic_site || Not Reported | biospecimen_laterality || Not Reported | biospecimen_type || Not Reported | bone_marrow_malignant_cells || Not Reported | burkitt_lymphoma_clinical_variant || Not Reported | cause_of_death || Not Reported | cause_of_death_source || Not Reported | cdc_hiv_risk_factors || Not Reported | chemo_concurrent_to_radiation || Not Reported | child_pugh_classification || Not Reported | chromosome || Not Reported | cog_liver_stage || Not Reported | cog_neuroblastoma_risk_group || Not Reported | cog_renal_stage || Not Reported | cog_rhabdomyosarcoma_risk_group || Not Reported | columnar_mucosa_present || Not Reported | comorbidity || Not Reported | comorbidity_method_of_diagnosis || Not Reported | composition || Not Reported | consistent_pathology_review || Not Reported | diabetes_treatment_type || Not Reported | diagnosis_pathologically_confirmed || Not Reported | disease_response || Not Reported | disease_type || Not Reported | distance_normal_to_tumor || Not Reported | dysplasia_degree || Not Reported | dysplasia_type || Not Reported | ecog_performance_status || Not Reported | eln_risk_classification || Not Reported | enneking_msts_grade || Not Reported | enneking_msts_metastasis || Not Reported | enneking_msts_stage || Not Reported | enneking_msts_tumor_site || Not Reported | esophageal_columnar_dysplasia_degree || Not Reported | esophageal_columnar_metaplasia_present || Not Reported | exposure_duration || Not Reported | eye_color || Not Reported | figo_stage || Not Reported | first_symptom_prior_to_diagnosis || Not Reported | gastric_esophageal_junction_involvement || Not Reported | gene_symbol || Not Reported | gleason_grade_group || Not Reported | goblet_cells_columnar_mucosa_present || Not Reported | haart_treatment_indicator || Not Reported | hepatitis_sustained_virological_response || Not Reported | histone_family || Not Reported | histone_variant || Not Reported | history_of_tumor || Not Reported | hormonal_contraceptive_type || Not Reported | hormonal_contraceptive_use || Not Reported | hormone_replacement_therapy_type || Not Reported | hpv_positive_type || Not Reported | hysterectomy_margins_involved || Not Reported | hysterectomy_type || Not Reported | igcccg_stage || Not Reported | imaging_result || Not Reported | immunosuppressive_treatment_type || Not Reported | initial_disease_status || Not Reported | inpc_grade || Not Reported | inpc_histologic_group || Not Reported | inrg_stage || Not Reported | inss_stage || Not Reported | instrument_model || Not Reported | irs_group || Not Reported | irs_stage || Not Reported | ishak_fibrosis_score || Not Reported | iss_stage || Not Reported | karnofsky_performance_status || Not Reported | laboratory_test || Not Reported | largest_extrapelvic_peritoneal_focus || Not Reported | laterality || Not Reported | lymph_node_involved_site || Not Reported | lymph_node_involvement || Not Reported | lymphatic_invasion_present || Not Reported | margin_status || Not Reported | medulloblastoma_molecular_classification || Not Reported | menopause_status || Not Reported | metaplasia_present || Not Reported | metastasis_at_diagnosis || Not Reported | metastasis_at_diagnosis_site || Not Reported | method_of_diagnosis || Not Reported | method_of_sample_procurement || Not Reported | micropapillary_features || Not Reported | mismatch_repair_mutation || Not Reported | mitosis_karyorrhexis_index || Not Reported | molecular_analysis_method || Not Reported | morphology || Not Reported | necrosis_present || Not Reported | non_nodal_regional_disease || Not Reported | non_nodal_tumor_deposits || Not Reported | normal_tumor_genotype_snp_match || Not Reported | ovarian_specimen_status || Not Reported | ovarian_surface_involvement || Not Reported | parent_with_radiation_exposure || Not Reported | perineural_invasion_present || Not Reported | peripancreatic_lymph_nodes_positive || Not Reported | peritoneal_fluid_cytological_status || Not Reported | ploidy || Not Reported | pregnancy_outcome || Not Reported | pregnant_at_diagnosis || Not Reported | premature_at_birth || Not Reported | preservation_method || Not Reported | primary_diagnosis || Not Reported | primary_site || Not Reported | prior_treatment || Not Reported | procedures_performed || Not Reported | progression_or_recurrence || Not Reported | progression_or_recurrence_anatomic_site || Not Reported | progression_or_recurrence_type || Not Reported | radon_exposure || Not Reported | reflux_treatment_type || Not Reported | relationship_primary_diagnosis || Not Reported | relationship_type || Not Reported | residual_disease || Not Reported | rhabdoid_present || Not Reported | risk_factor || Not Reported | risk_factor_treatment || Not Reported | route_of_administration || Not Reported | sample_type || Not Reported | sarcomatoid_present || Not Reported | satellite_nodule_present || Not Reported | second_gene_symbol || Not Reported | secondhand_smoke_as_child || Not Reported | site_of_resection_or_biopsy || Not Reported | supratentorial_localization || Not Reported | synchronous_malignancy || Not Reported | test_analyte_type || Not Reported | test_result || Not Reported | test_units || Not Reported | therapeutic_agents || Not Reported | tissue_or_organ_of_origin || Not Reported | tissue_type || Not Reported | tobacco_smoking_status || Not Reported | transglottic_extension || Not Reported | treatment_anatomic_site || Not Reported | treatment_effect || Not Reported | treatment_effect_indicator || Not Reported | treatment_frequency || Not Reported | treatment_intent_type || Not Reported | treatment_outcome || Not Reported | treatment_type || Not Reported | tumor_confined_to_organ_of_origin || Not Reported | tumor_descriptor || Not Reported | tumor_focality || Not Reported | tumor_grade || Not Reported | tumor_regression_grade || Not Reported | undescended_testis_corrected || Not Reported | undescended_testis_corrected_laterality || Not Reported | undescended_testis_corrected_method || Not Reported | undescended_testis_history || Not Reported | undescended_testis_history_laterality || Not Reported | variant_type || Not Reported | vascular_invasion_present || Not Reported | vascular_invasion_type || Not Reported | viral_hepatitis_serologies || Not Reported | vital_status || Not Reported | who_cns_grade || Not Reported | who_nte_grade || Not Reported | wilms_tumor_histologic_subtype || Not Reported | zygosity || not reported | classification_of_tumor || not reported | ethnicity || not reported | gender || not reported | last_known_disease_status || not reported | prior_malignancy || not reported | progression_or_recurrence || not reported | race || not reported | relationship_gender || not reported | relative_with_cancer_history || not reported | treatment_or_therapy || not reported | vital_status C102562 || C105721 || C106304 || C106317 || C106541 || C111073 || C112400 || C121007 || C123560 || C125738 || C126378 || C127768 || C127772 || C129439 || C13202 || C133427 || C133706 || C139007 || C140258 || C140259 || C140262 || C140266 || C141342 || C142346 || C15256 || C15599 || C156421 || C156422 || C157110 || C157233 || C157410 || C157425 || C157437 || C158874 || C160720 || C160827 || C160996 || C16124 || C161320 || C16165 || C162221 || C16457 || C16564 || C166229 || C16687 || C17001 || C17049 || C17103 || C171253 || C171435 || C173544 || C17357 || C173595 || C174459 || C175524 || C176287 || C176708 || C176985 || C177549 || C177550 || C177555 || C177556 || C177557 || C177558 || C177559 || C177561 || C177562 || C177564 || C177565 || C177566 || C177567 || C177568 || C177570 || C177571 || C177572 || C177573 || C177576 || C177578 || C177585 || C177586 || C177587 || C177588 || C177589 || C177590 || C177591 || C177592 || C177593 || C177594 || C177595 || C177596 || C177597 || C177598 || C177599 || C177600 || C177601 || C177602 || C177603 || C177605 || C177606 || C177607 || C177608 || C177609 || C177610 || C177611 || C177612 || C177616 || C177617 || C177619 || C177620 || C177621 || C177622 || C177624 || C177625 || C177626 || C177630 || C177631 || C177632 || C177633 || C177634 || C177635 || C177636 || C177637 || C177638 || C177640 || C177641 || C178243 || C178276 || C178286 || C178287 || C178288 || C178289 || C181720 || C181723 || C182060 || C182097 || C182099 || C182101 || C182102 || C182109 || C18849 || C18919 || C1909 || C19232 || C19697 || C19770 || C19796 || C25185 || C25218 || C25294 || C25717 || C268 || C28013 || C28076 || C29878 || C2991 || C33027 || C35529 || C36037 || C36292 || C38032 || C38114 || C39694 || C4086 || C45824 || C45902 || C4809 || C49236 || C50995 || C53414 || C54398 || C55816 || C574 || C67415 || C70700 || C70713 || C70729 || C81229 || C81239 || C83280 || C83315 || C83393 || C85416 || C89081 || C90491 || C92808 || C93431 || C95149 || C99532 inpc_grade || ecog_performance_status || tumor_regression_grade || mitosis_karyorrhexis_index || menopause_status || igcccg_stage || premature_at_birth || child_pugh_classification || margin_status || figo_stage || alcohol_intensity || perineural_invasion_present || vascular_invasion_present || medulloblastoma_molecular_classification || chromosome || inrg_stage || mismatch_repair_mutation || iss_stage || enneking_msts_stage || enneking_msts_grade || enneking_msts_tumor_site || enneking_msts_metastasis || chemo_concurrent_to_radiation || gleason_grade_group || hysterectomy_type || hormone_replacement_therapy_type || site_of_resection_or_biopsy || tissue_or_organ_of_origin || hpv_positive_type || first_symptom_prior_to_diagnosis || hormonal_contraceptive_use || tumor_focality || eye_color || primary_site || lymphatic_invasion_present || satellite_nodule_present || transglottic_extension || prior_treatment || synchronous_malignancy || haart_treatment_indicator || metastasis_at_diagnosis || comorbidity || ethnicity || tumor_descriptor || histone_family || ploidy || race || risk_factor || second_gene_symbol || biospecimen_anatomic_site || variant_type || gender || gene_symbol || classification_of_tumor || peritoneal_fluid_cytological_status || cause_of_death_source || imaging_result || morphology || irs_group || irs_stage || ajcc_clinical_stage || ajcc_pathologic_stage || test_analyte_type || ann_arbor_clinical_stage || ann_arbor_pathologic_stage || ajcc_staging_system_edition || eln_risk_classification || comorbidity_method_of_diagnosis || inpc_histologic_group || who_cns_grade || who_nte_grade || wilms_tumor_histologic_subtype || progression_or_recurrence_anatomic_site || supratentorial_localization || distance_normal_to_tumor || radon_exposure || method_of_diagnosis || dysplasia_degree || ann_arbor_b_symptoms || ann_arbor_extranodal_involvement || bone_marrow_malignant_cells || burkitt_lymphoma_clinical_variant || columnar_mucosa_present || diagnosis_pathologically_confirmed || esophageal_columnar_metaplasia_present || gastric_esophageal_junction_involvement || barretts_esophagus_goblet_cells_present || goblet_cells_columnar_mucosa_present || hysterectomy_margins_involved || metaplasia_present || necrosis_present || non_nodal_regional_disease || non_nodal_tumor_deposits || normal_tumor_genotype_snp_match || ovarian_surface_involvement || progression_or_recurrence || rhabdoid_present || risk_factor_treatment || biospecimen_laterality || ajcc_clinical_m || ajcc_pathologic_m || ovarian_specimen_status || viral_hepatitis_serologies || instrument_model || ajcc_clinical_n || ajcc_pathologic_n || initial_disease_status || last_known_disease_status || pregnant_at_diagnosis || histone_variant || primary_diagnosis || relationship_gender || cdc_hiv_risk_factors || metastasis_at_diagnosis_site || secondhand_smoke_as_child || cog_liver_stage || cog_neuroblastoma_risk_group || cog_renal_stage || cog_rhabdomyosarcoma_risk_group || hepatitis_sustained_virological_response || ajcc_clinical_t || ajcc_pathologic_t || reflux_treatment_type || treatment_effect_indicator || progression_or_recurrence_type || esophageal_columnar_dysplasia_degree || relationship_primary_diagnosis || peripancreatic_lymph_nodes_positive || anaplasia_present || anaplasia_present_type || vascular_invasion_type || largest_extrapelvic_peritoneal_focus || consistent_pathology_review || undescended_testis_corrected_laterality || parent_with_radiation_exposure || undescended_testis_corrected || undescended_testis_history || undescended_testis_corrected_method || undescended_testis_history_laterality || adrenal_hormone || history_of_tumor || prior_malignancy || treatment_outcome || therapeutic_agents || preservation_method || tissue_type || molecular_analysis_method || tobacco_smoking_status || laterality || treatment_type || laboratory_test || vital_status || antigen || karnofsky_performance_status || tumor_grade || relative_with_cancer_history || disease_type || lymph_node_involved_site || lymph_node_involvement || tumor_confined_to_organ_of_origin || test_result || treatment_effect || route_of_administration || sarcomatoid_present || dysplasia_type || zygosity || alcohol_type || residual_disease || treatment_or_therapy || disease_response || composition || treatment_intent_type || asbestos_exposure || immunosuppressive_treatment_type || test_units || method_of_sample_procurement || sample_type || treatment_anatomic_site || alcohol_history || cause_of_death || exposure_duration || biospecimen_type || relationship_type || inss_stage || treatment_frequency || pregnancy_outcome || hormonal_contraceptive_type || procedures_performed || ishak_fibrosis_score || diabetes_treatment_type C C177537 GDC Value Terminology C43236 WAS Gene This gene is involved in signal transduction and plays a role in cell communication and organization. WAS | gene_symbol || WAS | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C43569 CDC73 Gene This gene is involved in transcription and may play a role in cell cycle progression. CDC73 | gene_symbol || CDC73 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C45437 PDCD1LG2 Gene This gene plays a role in the regulation of T-cell proliferation. PDCD1LG2 | gene_symbol || PDCD1LG2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C45497 FES Gene This gene is involved in hematopoiesis and the maintenance of cellular transformation. FES | gene_symbol || FES | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C45602 Bronchial Mixed Squamous Cell and Glandular Papilloma An exceedingly rare benign endobronchial neoplasm characterized by the presence of fibrovascular cores which are lined by both squamous and glandular epithelium. Patients present with obstructive symptoms. Complete resection is curative. 8560/0 | morphology || Mixed squamous cell and glandular papilloma | primary_diagnosis C176985 || C177621 morphology || primary_diagnosis C C177537 GDC Value Terminology C46071 CYP2C8 Gene This gene plays a role in drug metabolism. It is also involved in the oxidation of both endobiotics and xenobiotics. CYP2C8 | gene_symbol || CYP2C8 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C48329 Green The hue of that portion of the visible spectrum lying between yellow and blue, evoked in the human observer by radiant energy with wavelengths of approximately 490 to 570 nanometers; any of a group of colors that may vary in lightness and saturation and whose hue is that of the emerald or somewhat less yellow than that of growing grass. Green | channel || Green | eye_color C157437 || C181706 eye_color || channel C C177537 GDC Value Terminology C48660 Not Applicable Determination of a value is not relevant in the current context. Not Applicable | chipseq_antibody || Not Applicable | disease_type || Not Applicable | fragmentation_enzyme || Not Applicable | gene_symbol || Not Applicable | library_strand || Not Applicable | read_pair_number || Not Applicable | reflux_treatment_type || Not Applicable | target_capture_kit || Not Applicable | tumor_descriptor C16515 || C166229 || C172300 || C173595 || C177563 || C177583 || C177613 || C177637 || C2991 fragmentation_enzyme || tumor_descriptor || read_pair_number || gene_symbol || library_strand || target_capture_kit || chipseq_antibody || reflux_treatment_type || disease_type C C177537 GDC Value Terminology C49018 Regional Lymph Node A lymph node that drains lymph from a region of interest. Lymph Node(s) Regional | biospecimen_anatomic_site || Lymph Node(s) Regional | treatment_anatomic_site || Lymph Node, Regional | metastasis_at_diagnosis_site C171435 || C177625 || C70729 biospecimen_anatomic_site || metastasis_at_diagnosis_site || treatment_anatomic_site C C177537 GDC Value Terminology C49487 No The non-affirmative response to a question. No | adrenal_hormone || No | alcohol_history || No | anaplasia_present || No | ann_arbor_b_symptoms || No | ann_arbor_extranodal_involvement || No | asbestos_exposure || No | barretts_esophagus_goblet_cells_present || No | bone_marrow_malignant_cells || No | chemo_concurrent_to_radiation || No | coal_dust_exposure || No | columnar_mucosa_present || No | consistent_pathology_review || No | diagnosis_pathologically_confirmed || No | environmental_tobacco_smoke_exposure || No | esophageal_columnar_metaplasia_present || No | gastric_esophageal_junction_involvement || No | goblet_cells_columnar_mucosa_present || No | haart_treatment_indicator || No | hepatitis_sustained_virological_response || No | history_of_tumor || No | lost_to_followup || No | lymphatic_invasion_present || No | metaplasia_present || No | mismatch_repair_mutation || No | necrosis_present || No | non_nodal_tumor_deposits || No | normal_tumor_genotype_snp_match || No | parent_with_radiation_exposure || No | perineural_invasion_present || No | pregnant_at_diagnosis || No | premature_at_birth || No | prior_treatment || No | progression_or_recurrence || No | radon_exposure || No | respirable_crystalline_silica_exposure || No | rhabdoid_present || No | risk_factor_treatment || No | sarcomatoid_present || No | secondhand_smoke_as_child || No | synchronous_malignancy || No | treatment_effect_indicator || No | tumor_confined_to_organ_of_origin || No | undescended_testis_corrected || No | undescended_testis_history || No | vascular_invasion_present || no | prior_malignancy || no | progression_or_recurrence || no | relative_with_cancer_history || no | treatment_or_therapy C112400 || C127768 || C127772 || C133706 || C141342 || C159824 || C160720 || C16124 || C161320 || C16165 || C17140 || C177573 || C177574 || C177575 || C177585 || C177586 || C177587 || C177589 || C177590 || C177591 || C177592 || C177593 || C177595 || C177596 || C177598 || C177599 || C177601 || C177602 || C177603 || C177619 || C177626 || C177634 || C177638 || C178286 || C181720 || C182060 || C182097 || C182099 || C182109 || C18849 || C29878 || C36037 || C39694 || C49236 || C55816 || C81229 premature_at_birth || perineural_invasion_present || vascular_invasion_present || mismatch_repair_mutation || chemo_concurrent_to_radiation || lost_to_followup || lymphatic_invasion_present || prior_treatment || synchronous_malignancy || haart_treatment_indicator || environmental_tobacco_smoke_exposure || radon_exposure || coal_dust_exposure || respirable_crystalline_silica_exposure || ann_arbor_b_symptoms || ann_arbor_extranodal_involvement || bone_marrow_malignant_cells || columnar_mucosa_present || diagnosis_pathologically_confirmed || esophageal_columnar_metaplasia_present || gastric_esophageal_junction_involvement || barretts_esophagus_goblet_cells_present || goblet_cells_columnar_mucosa_present || metaplasia_present || necrosis_present || non_nodal_tumor_deposits || normal_tumor_genotype_snp_match || progression_or_recurrence || rhabdoid_present || risk_factor_treatment || pregnant_at_diagnosis || secondhand_smoke_as_child || hepatitis_sustained_virological_response || treatment_effect_indicator || anaplasia_present || consistent_pathology_review || parent_with_radiation_exposure || undescended_testis_corrected || undescended_testis_history || adrenal_hormone || history_of_tumor || prior_malignancy || relative_with_cancer_history || tumor_confined_to_organ_of_origin || sarcomatoid_present || treatment_or_therapy || asbestos_exposure || alcohol_history C C177537 GDC Value Terminology C49488 Yes The affirmative response to a question. Yes | adrenal_hormone || Yes | alcohol_history || Yes | anaplasia_present || Yes | ann_arbor_b_symptoms || Yes | ann_arbor_extranodal_involvement || Yes | asbestos_exposure || Yes | barretts_esophagus_goblet_cells_present || Yes | bone_marrow_malignant_cells || Yes | chemo_concurrent_to_radiation || Yes | coal_dust_exposure || Yes | columnar_mucosa_present || Yes | consistent_pathology_review || Yes | diagnosis_pathologically_confirmed || Yes | environmental_tobacco_smoke_exposure || Yes | esophageal_columnar_metaplasia_present || Yes | gastric_esophageal_junction_involvement || Yes | goblet_cells_columnar_mucosa_present || Yes | haart_treatment_indicator || Yes | hepatitis_sustained_virological_response || Yes | history_of_tumor || Yes | lost_to_followup || Yes | lymphatic_invasion_present || Yes | metaplasia_present || Yes | mismatch_repair_mutation || Yes | necrosis_present || Yes | non_nodal_tumor_deposits || Yes | normal_tumor_genotype_snp_match || Yes | parent_with_radiation_exposure || Yes | perineural_invasion_present || Yes | pregnant_at_diagnosis || Yes | premature_at_birth || Yes | prior_treatment || Yes | progression_or_recurrence || Yes | radon_exposure || Yes | respirable_crystalline_silica_exposure || Yes | rhabdoid_present || Yes | risk_factor_treatment || Yes | sarcomatoid_present || Yes | secondhand_smoke_as_child || Yes | synchronous_malignancy || Yes | treatment_effect_indicator || Yes | tumor_confined_to_organ_of_origin || Yes | undescended_testis_corrected || Yes | undescended_testis_history || Yes | vascular_invasion_present || yes | prior_malignancy || yes | progression_or_recurrence || yes | relative_with_cancer_history || yes | treatment_or_therapy C112400 || C127768 || C127772 || C133706 || C141342 || C159824 || C160720 || C16124 || C161320 || C16165 || C17140 || C177573 || C177574 || C177575 || C177585 || C177586 || C177587 || C177589 || C177590 || C177591 || C177592 || C177593 || C177595 || C177596 || C177598 || C177599 || C177601 || C177602 || C177603 || C177619 || C177626 || C177634 || C177638 || C178286 || C181720 || C182060 || C182097 || C182099 || C182109 || C18849 || C29878 || C36037 || C39694 || C49236 || C55816 || C81229 premature_at_birth || perineural_invasion_present || vascular_invasion_present || mismatch_repair_mutation || chemo_concurrent_to_radiation || lost_to_followup || lymphatic_invasion_present || prior_treatment || synchronous_malignancy || haart_treatment_indicator || environmental_tobacco_smoke_exposure || radon_exposure || coal_dust_exposure || respirable_crystalline_silica_exposure || ann_arbor_b_symptoms || ann_arbor_extranodal_involvement || bone_marrow_malignant_cells || columnar_mucosa_present || diagnosis_pathologically_confirmed || esophageal_columnar_metaplasia_present || gastric_esophageal_junction_involvement || barretts_esophagus_goblet_cells_present || goblet_cells_columnar_mucosa_present || metaplasia_present || necrosis_present || non_nodal_tumor_deposits || normal_tumor_genotype_snp_match || progression_or_recurrence || rhabdoid_present || risk_factor_treatment || pregnant_at_diagnosis || secondhand_smoke_as_child || hepatitis_sustained_virological_response || treatment_effect_indicator || anaplasia_present || consistent_pathology_review || parent_with_radiation_exposure || undescended_testis_corrected || undescended_testis_history || adrenal_hormone || history_of_tumor || prior_malignancy || relative_with_cancer_history || tumor_confined_to_organ_of_origin || sarcomatoid_present || treatment_or_therapy || asbestos_exposure || alcohol_history C C177537 GDC Value Terminology C5264 Lung Mucosa-Associated Lymphoid Tissue Lymphoma An extranodal marginal zone lymphoma that arises from the lung. It is characterized by the neoplastic proliferation of small B-lymphocytes, monocytoid cells and cells with plasma cell differentiation in the marginal zones of reactive lymphoid follicles. The neoplastic cells infiltrate the interfollicular areas and the bronchial epithelium forming lymphoepithelial lesions. The neoplasm is usually discovered as a mass in a chest x-ray in asymptomatic patients. When symptoms occur, they include cough, dyspnea, hemoptysis, and chest pain. If the lung lesions are resectable, surgery can result in prolonged remission. 9699/3 | morphology || BALT lymphoma | primary_diagnosis || Bronchial-associated lymphoid tissue lymphoma | primary_diagnosis C176985 || C177621 morphology || primary_diagnosis C C177537 GDC Value Terminology C53661 ITGAV Gene This gene plays a role in cell communication and angiogenesis. ITGAV | gene_symbol || ITGAV | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C54237 NFE2L2 Gene This gene plays a role in transcriptional regulation. NFE2L2 | gene_symbol || NFE2L2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C60668 CARD11 Gene This gene plays a role in apoptotic regulation. CARD11 | gene_symbol || CARD11 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C60671 MALT1 Gene This gene plays a role in signal transduction and in the pathology of mucosa-associated lymphoid tissue lymphomas. MALT1 | gene_symbol || MALT1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C61056 MUTYH Gene This gene plays a role in the repair of oxidative DNA damage. MUTYH | gene_symbol || MUTYH | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C61136 SOX2 Gene This gene is involved in embryonic development and in the determination of cell fate. SOX2 | gene_symbol || SOX2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C61140 POU5F1 Gene This gene plays a role in early mammalian development. POU5F1 | gene_symbol || POU5F1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C61148 LMNA Gene This gene is involved in the architecture of nuclear membrane construction. LMNA | gene_symbol || LMNA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C62660 B2M Gene This gene plays a role in immune responses. B2M | gene_symbol || B2M | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C62726 Hypofractionated Radiation Therapy Radiation treatment in which the total dose of radiation is divided into large doses and treatments are given less than once a day. Radiation, Hypofractionated | treatment_type C25218 treatment_type C C177537 GDC Value Terminology C63331 Microsatellite Instability Analysis A laboratory procedure to detect microsatellite instability. Microsatellite Analysis | laboratory_test || Microsatellite Analysis | molecular_analysis_method C19770 || C25294 molecular_analysis_method || laboratory_test C C177537 GDC Value Terminology C63514 FLCN Gene This gene may play a role in tumor suppression. FLCN | gene_symbol || FLCN | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C63526 BRIP1 Gene This gene is involved in DNA double-strand break repair. BRIP1 | gene_symbol || BRIP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C68575 OLIG2 Gene This gene is involved in transcriptional regulation and oligodendrocyte and motor neuron differentiation. This gene may play a role in the development of brain tumors. OLIG2 | gene_symbol || OLIG2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C68718 AMER1 Gene This gene may play a role in kidney development. AMER1 | gene_symbol || AMER1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C68722 EZR Gene This gene plays a role in cellular structure. EZR | gene_symbol || EZR | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C68730 IKZF1 Gene This gene is involved in B-cell and T-cell maturation. IKZF1 | gene_symbol || IKZF1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C68734 H4C9 Gene This gene plays a role in nucleosomal structure. HIST1H4I | gene_symbol || HIST1H4I | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C68736 IL21R Gene This gene is involved in cytokine recognition. IL21R | gene_symbol || IL21R | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C69184 SKI Gene This gene is involved in transcriptional regulation and is involved in cellular signal transduction. SKI | gene_symbol || SKI | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C6975 Papillary Renal Cell Carcinoma Also known as chromophil carcinoma, it represents a minority of renal cell carcinomas. It can be hereditary or sporadic. The sporadic papillary renal cell carcinoma is characterized by trisomy of chromosomes 7, 16, and 17, and loss of chromosome Y. The peak incidence is in the sixth and seven decades. It is classified as type 1 or 2, based on the cytoplasmic volume and the thickness of the lining neoplastic cells. The prognosis is more favorable than for conventional (clear cell) renal cell carcinoma. 51 | tumor_code_id || 71 | tumor_code_id || 8260/3 | morphology || Papillary Renal Cell | morphologic_architectural_pattern || Papillary renal cell carcinoma | primary_diagnosis C176985 || C177584 || C177621 || C35886 morphology || tumor_code_id || primary_diagnosis || morphologic_architectural_pattern C C177537 GDC Value Terminology C70584 MITF Gene This gene is involved in transcriptional promotion in melanocytes. MITF | gene_symbol || MITF | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C70991 ASPSCR1 Gene This gene is involved in the modulation of blood glucose levels. ASPSCR1 | gene_symbol || ASPSCR1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C70994 PRCC Gene This gene may be involved in transcriptional regulation. PRCC | gene_symbol || PRCC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C71003 EML4 Gene This gene may play a role in cytoskeletal assembly. EML4 | gene_symbol || EML4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C71018 MUC16 Gene This gene is involved in both cellular adhesion and the maintenance of mucosal surfaces. MUC16 | gene_symbol || MUC16 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C71417 SFPQ Gene This gene may be involved in both transcriptional regulation and nuclear RNA processing. SFPQ | gene_symbol || SFPQ | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C71419 NONO Gene This gene may play a role in both transcriptional regulation and nuclear RNA processing. NONO | gene_symbol || NONO | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C71423 PLAG1 Gene This gene is involved in cellular proliferation. PLAG1 | gene_symbol || PLAG1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C71429 KAT6A Gene This gene is involved in both histone acetylation and transcriptional regulation. KAT6A | gene_symbol || KAT6A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C71431 KAT6B Gene This gene plays a role in both transcription and histone acetylation. KAT6B | gene_symbol || KAT6B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C7270 Minimally Invasive Lung Mixed Non-Mucinous and Mucinous Adenocarcinoma A morphologic variant of minimally invasive lung adenocarcinoma characterized by the presence of Clara cells and/or type II cells, tall columnar cells, and mucin production. 8254/3 | morphology || Bronchio-alveolar carcinoma, mixed mucinous and non-mucinous | primary_diagnosis || Bronchiolo-alveolar carcinoma, Clara cell and goblet cell type | primary_diagnosis || Bronchiolo-alveolar carcinoma, indeterminate type | primary_diagnosis || Bronchiolo-alveolar carcinoma, type II pneumocyte and goblet cell type | primary_diagnosis C176985 || C177621 morphology || primary_diagnosis C C177537 GDC Value Terminology C73443 NKX2-1 Gene This gene plays a role in thyroid gene transcription. NKX2-1 | gene_symbol || NKX2-1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C73449 KLF4 Gene This gene plays a role in gene transcription. KLF4 | gene_symbol || KLF4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C73461 CNTNAP2 Gene This gene may be involved in axonal structure. CNTNAP2 | gene_symbol || CNTNAP2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C73542 JAZF1 Gene This gene may be involved in transcriptional regulation. JAZF1 | gene_symbol || JAZF1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C73545 SUZ12 Gene This gene plays a role in embryonic development and histone methylation. SUZ12 | gene_symbol || SUZ12 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C73652 DNMT3A Gene This gene is involved in epigenetic modification of DNA. DNMT3A | gene_symbol || DNMT3A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C73660 KAT7 Gene This gene is involved in epigenetic control of gene expression. KAT7 | gene_symbol || KAT7 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C73662 SETD2 Gene This gene is involved in epigenetic control of gene expression. SETD2 | gene_symbol || SETD2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C73679 CTCF Gene This gene is involved in epigenetic control of gene expression. CTCF | gene_symbol || CTCF | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C74976 ATRX Gene This gene plays a role in the regulation of both chromatin remodeling and transcription. ATRX | gene_symbol || ATRX | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C75013 BTK Gene This gene is involved in both signaling and B-cell development. BTK | gene_symbol || BTK | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C75307 CHD2 Gene This gene may be involved in the regulation of both gene expression and chromatin modification. CHD2 | gene_symbol || CHD2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C75315 COL2A1 Gene This gene plays a role in both skeletal development and cartilage structure. COL2A1 | gene_symbol || COL2A1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C75333 ELN Gene This gene is involved in the structure of the extracellular matrix. ELN | gene_symbol || ELN | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C75406 SMC1A Gene This gene is involved in maintenance of sister chromatid cohesion during mitosis. SMC1A | gene_symbol || SMC1A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C75472 FOXL2 Gene This gene plays a role in ovarian function. FOXL2 | gene_symbol || FOXL2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C75492 GATA3 Gene This gene plays a role in the modulation of transcription. GATA3 | gene_symbol || GATA3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C75876 NSD1 Gene This gene is involved in the mediation of histone methylation. NSD1 | gene_symbol || NSD1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C77215 IDH1 Gene This gene plays a role in carbohydrate metabolism. IDH1 | gene_symbol || IDH1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C79770 CTNND1 Gene This gene plays a role in signal transduction. CTNND1 | gene_symbol || CTNND1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C80023 EBF1 Gene This gene plays a role in transcriptional activation. EBF1 | gene_symbol || EBF1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C80032 LEF1 Gene This gene plays a role in both signal transduction and transcription. LEF1 | gene_symbol || LEF1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C80101 BTG1 Gene This gene is involved in the regulation of cell proliferation. BTG1 | gene_symbol || BTG1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C80116 TBL1XR1 Gene This gene is involved in transcriptional activation. TBL1XR1 | gene_symbol || TBL1XR1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C82941 CTNND2 Gene This gene is involved in the regulation of both transcription and signal transduction. CTNND2 | gene_symbol || CTNND2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C84301 ANK1 Gene This gene plays a role in red blood cell morphology. ANK1 | gene_symbol || ANK1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C84434 PICALM Gene This gene plays a role in receptor mediated endocytosis. PICALM | gene_symbol || PICALM | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C84461 MLLT10 Gene This gene may be involved in transcriptional regulation. MLLT10 | gene_symbol || MLLT10 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C84464 CLIP1 Gene This gene plays a role in both endocytosis and mitosis. CLIP1 | gene_symbol || CLIP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C84921 ALDH2 Gene This gene plays a role in intermediary metabolism. ALDH2 | gene_symbol || ALDH2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C84928 TNFAIP3 Gene This gene may play a role in the regulation of apoptosis. TNFAIP3 | gene_symbol || TNFAIP3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C84945 PALB2 Gene This gene may play a role in the repair of DNA damage that is resolved by recombination. PALB2 | gene_symbol || PALB2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C84948 IDH2 Gene This gene plays a role in intermediary metabolism. IDH2 | gene_symbol || IDH2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C85995 FANCA Gene This gene may be involved in the mediation of DNA repair. FANCA | gene_symbol || FANCA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C86025 FANCC Gene This gene may play a role in DNA cross-link repair. FANCC | gene_symbol || FANCC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C86549 FANCD2 Gene This gene is involved in the regulation of meiosis, DNA repair and the cell cycle. FANCD2 | gene_symbol || FANCD2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C86551 FANCE Gene This gene plays a role in the regulation of both DNA repair and protein localization. FANCE | gene_symbol || FANCE | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C86553 FANCF Gene This gene may be involved in the regulation of DNA repair. FANCF | gene_symbol || FANCF | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C88173 GPC3 Gene This gene is involved in heparin sulfate binding. GPC3 | gene_symbol || GPC3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C88179 PPM1D Gene This gene plays a role in the modulation of cell cycle arrest. PPM1D | gene_symbol || PPM1D | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C88218 MDM4 Gene This gene plays a role in both cell cycle arrest and the inhibition of apoptosis. MDM4 | gene_symbol || MDM4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C89717 GNA11 Gene This gene is involved in signal transduction. GNA11 | gene_symbol || GNA11 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C90089 MYD88 Gene This gene is involved in the modulation of proinflammatory gene expression. MYD88 | gene_symbol || MYD88 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C90145 RAD51B Gene This gene plays a role in the mediation of homologous recombinational repair of DNA. RAD51B | gene_symbol || RAD51B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C90373 Clinical Trial Agent The pharmacological substance that is being administered in the study. Clinical Trial | therapeutic_agents || Clinical Trial Agent | therapeutic_agents C1909 therapeutic_agents C C177537 GDC Value Terminology C91263 LMO1 Gene This gene is involved in the regulation of transcription. LMO1 | gene_symbol || LMO1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C91356 MSI2 Gene This gene is involved in translational regulation. MSI2 | gene_symbol || MSI2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C91369 ACKR3 Gene This gene is involved in the regulation of chemokine signaling. ACKR3 | gene_symbol || ACKR3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C91791 TP63 Gene This gene plays a role in both transcriptional regulation and limb development. TP63 | gene_symbol || TP63 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C91852 FUS Gene This gene is involved in gene expression, genomic integrity and RNA processing. FUS | gene_symbol || FUS | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C91855 BCL11B Gene This gene may play a role in tumor suppression, signaling and T cell development. BCL11B | gene_symbol || BCL11B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C92177 ATF1 Gene This gene is involved in the modulation of transcription. ATF1 | gene_symbol || ATF1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C92530 ARID1A Gene This gene plays a role in transcriptional regulation. ARID1A | gene_symbol || ARID1A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C92536 PPP2R1A Gene This gene plays a role in the regulation of cell growth and division. PPP2R1A | gene_symbol || PPP2R1A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C92539 DDIT3 Gene This gene plays a role in the modulation of transcription. DDIT3 | gene_symbol || DDIT3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C92663 DGCR8 Gene This gene plays a role in microRNA processing. DGCR8 | gene_symbol || DGCR8 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C92678 CYLD Gene This gene is involved in protein deubiquitination. CYLD | gene_symbol || CYLD | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C92696 MALAT1 Gene This gene may play a role in carcinogenesis. MALAT1 | gene_symbol || MALAT1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C92699 TCL1A Gene This gene is involved in signal transduction. TCL1A | gene_symbol || TCL1A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C92702 BRD4 Gene This gene plays a role in mitosis. BRD4 | gene_symbol || BRD4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C92705 NUTM1 Gene This gene may be involved in testicular function. NUTM1 | gene_symbol || NUTM1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C93075 DDB2 Gene This gene plays a role in DNA repair. DDB2 | gene_symbol || DDB2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C93082 RAD21 Gene This gene is involved in chromosomal cohesion, DNA repair and apoptosis. RAD21 | gene_symbol || RAD21 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C93091 KMT2C Gene This gene plays a role in both methylation and transcriptional regulation KMT2C | gene_symbol || KMT2C | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C93113 MYOD1 Gene This gene plays a role in DNA binding and myogenesis. MYOD1 | gene_symbol || MYOD1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C93138 NFATC2 Gene This gene is involved in cytokine gene transcription. NFATC2 | gene_symbol || NFATC2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C94761 TFEB Gene This gene plays a role in transcription. TFEB | gene_symbol || TFEB | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95252 TET2 Gene This gene is involved in oxidation. TET2 | gene_symbol || TET2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95268 FH Gene This gene plays a role in the Krebs cycle. FH | gene_symbol || FH | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95276 CRTC3 Gene This gene is involved in transcriptional regulation. CRTC3 | gene_symbol || CRTC3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95280 TRIM24 Gene This gene plays a role in hormone-dependent gene transcription. TRIM24 | gene_symbol || TRIM24 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95303 TMEM127 Gene This gene may play a role in signaling and protein trafficking. TMEM127 | gene_symbol || TMEM127 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95313 CALR Gene This gene plays a role in calcium binding and protein folding. CALR | gene_symbol || CALR | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95423 TET1 Gene This gene is involved in the regulation of DNA methylation. TET1 | gene_symbol || TET1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95438 PBRM1 Gene This gene plays a role in chromatin remodeling. PBRM1 | gene_symbol || PBRM1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95449 CRTC1 Gene This gene plays a role in the positive regulation of transcription. CRTC1 | gene_symbol || CRTC1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95456 MAML2 Gene This gene plays a role in transcriptional regulation and signal transduction. MAML2 | gene_symbol || MAML2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95477 CREB3L1 Gene This gene plays a role in transcriptional regulation in response to cellular stress. CREB3L1 | gene_symbol || CREB3L1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95480 CREB3L2 Gene This gene is involved in the response to cellular stress. CREB3L2 | gene_symbol || CREB3L2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95578 CUX1 Gene This gene is involved in both transcriptional regulation and Golgi vesicle transport. CUX1 | gene_symbol || CUX1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95592 BUB1B Gene This gene is involved in mitotic progression. BUB1B | gene_symbol || BUB1B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95838 KCNJ5 Gene This gene is involved in ion transport. KCNJ5 | gene_symbol || KCNJ5 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95865 PCBP1 Gene This gene plays a role in RNA splicing. PCBP1 | gene_symbol || PCBP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C95994 TAF15 Gene This gene plays a role in transcriptional initiation. TAF15 | gene_symbol || TAF15 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C96007 NR4A3 Gene This gene is involved in the modulation of transcription. NR4A3 | gene_symbol || NR4A3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C96013 CIITA Gene This gene plays a role in transcriptional regulation. CIITA | gene_symbol || CIITA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C96022 CD274 Gene This gene is involved in T cell activation and proliferation. CD274 | gene_symbol || CD274 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C96027 RMI2 Gene This gene is involved in DNA replication. RMI2 | gene_symbol || RMI2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C96316 TENT5C Gene This gene is involved in polyadenylation of RNA and mRNA stability. FAM46C | gene_symbol || FAM46C | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C96331 SND1 Gene This gene plays a role in both transcriptional regulation and RNA interference. SND1 | gene_symbol || SND1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C96334 KDM6A Gene This gene is involved in the modulation of histone methylation. KDM6A | gene_symbol || KDM6A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C96341 NSD3 Gene This gene is involved in histone methylation. NSD3 | gene_symbol || NSD3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C96383 IKBKB Gene This gene is involved in protein phosphorylation. IKBKB | gene_symbol || IKBKB | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C96444 KRT7 Gene This gene plays a role in DNA replication. KRT7 | gene_symbol C173595 gene_symbol C C177537 GDC Value Terminology C96457 KRT20 Gene This gene plays a role in the formation of intestinal epithelia. KRT20 | gene_symbol C173595 gene_symbol C C177537 GDC Value Terminology C97279 ARHGAP5 Gene This gene is involved in the regulation of GTPase activity. ARHGAP5 | gene_symbol || ARHGAP5 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97290 RPN1 Gene This gene plays a role in post-translational protein modification. RPN1 | gene_symbol || RPN1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97293 RBM15 Gene This gene plays a role in RNA binding. RBM15 | gene_symbol || RBM15 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97296 MRTFA Gene This gene is involved in transcriptional modulation and muscle cell differentiation. MKL1 | gene_symbol || MKL1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97317 PBX1 Gene This gene plays a role in the modulation of transcription. PBX1 | gene_symbol || PBX1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97320 ASXL1 Gene This gene may be involved in both transcriptional regulation and chromatin remodeling. ASXL1 | gene_symbol || ASXL1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97365 ACSL3 Gene This gene is involved in lipid biosynthesis. ACSL3 | gene_symbol || ACSL3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97369 CARS1 Gene This gene is involved in transfer RNA metabolism. CARS | gene_symbol || CARS | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97372 CCNB1IP1 Gene This gene plays a role in both ubiquitination and cell cycle progression. CCNB1IP1 | gene_symbol || CCNB1IP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97375 CANT1 Gene This gene plays a role in both nucleotide hydrolysis and signal transduction. CANT1 | gene_symbol || CANT1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97378 KNL1 Gene This gene is involved in both signaling and chromosome alignment in mitosis. KNL1 | gene_symbol || KNL1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97381 CCND3 Gene This gene is involved in cell cycle progression. CCND3 | gene_symbol || CCND3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97384 CDK6 Gene This gene plays a role in the progression of the cell cycle. CDK6 | gene_symbol || CDK6 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97387 MLLT11 Gene This gene is involved in mitochondrial functions. MLLT11 | gene_symbol || MLLT11 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97390 RNF213 Gene This gene may be involved in ubiquitination. RNF213 | gene_symbol || RNF213 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97394 BCL11A Gene This gene is involved in both the modulation of cell shape and lymphopoiesis. BCL11A | gene_symbol || BCL11A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97397 BRD3 Gene This gene may play a role in both histone acetylation and transcriptional regulation. BRD3 | gene_symbol || BRD3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97400 ATIC Gene This gene plays a role in purine biosynthesis. ATIC | gene_symbol || ATIC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97403 CHCHD7 Gene This gene may be involved in stature. CHCHD7 | gene_symbol || CHCHD7 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97406 CHIC2 Gene This gene may play a role in vesicular transport. CHIC2 | gene_symbol || CHIC2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97412 CLTC Gene This gene plays a role in both the formation of cellular vesicles and receptor-mediated endocytosis. CLTC | gene_symbol || CLTC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97415 CLTCL1 Gene This gene is involved in both receptor-mediated endocytosis and vesicle formation. CLTCL1 | gene_symbol || CLTCL1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97418 CD74 Gene This gene plays a role in antigen processing and presentation. CD74 | gene_symbol || CD74 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97421 CD79A Gene This gene is involved in B-cell signaling and proliferation. CD79A | gene_symbol || CD79A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97424 CD79B Gene This gene plays a role in signaling in B-cells. CD79B | gene_symbol || CD79B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97427 CDH11 Gene This gene is involved in the adherens junction. CDH11 | gene_symbol || CDH11 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97430 CRLF2 Gene This gene is involved in cytokine binding and signaling. CRLF2 | gene_symbol || CRLF2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97433 NCKIPSD Gene This gene plays a role in stress fiber formation. NCKIPSD | gene_symbol || NCKIPSD | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97436 ARHGEF12 Gene This gene plays a role in both G-protein coupled receptor- and Rho-mediated signaling. ARHGEF12 | gene_symbol || ARHGEF12 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97439 CBLC Gene This gene is involved in both ubiquitination and signaling. CBLC | gene_symbol || CBLC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97445 CBFA2T3 Gene This gene plays a role in transcriptional regulation. CBFA2T3 | gene_symbol || CBFA2T3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97448 KLF6 Gene This gene plays a role in transcriptional activation. KLF6 | gene_symbol || KLF6 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97454 FIP1L1 Gene This gene is involved in mRNA processing. FIP1L1 | gene_symbol || FIP1L1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97457 DDX10 Gene This gene plays a role in both RNA metabolism and ATP hydrolysis. DDX10 | gene_symbol || DDX10 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97460 DDX5 Gene This gene is involved in the mediation of RNA metabolism. DDX5 | gene_symbol || DDX5 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97467 EIF4A2 Gene This gene is involved in translation initiation. EIF4A2 | gene_symbol || EIF4A2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97470 ELF4 Gene This gene plays a role in both DNA binding and transcriptional activation. ELF4 | gene_symbol || ELF4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97476 ELK4 Gene This gene is involved in the regulation of transcription. ELK4 | gene_symbol || ELK4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97479 ETV5 Gene This gene plays a role in the regulation of gene transcription. ETV5 | gene_symbol || ETV5 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97482 FEV Gene This gene may play a role in transcriptional repression. FEV | gene_symbol || FEV | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97493 HOOK3 Gene This gene plays a role in endocytosis and Golgi maintenance. HOOK3 | gene_symbol || HOOK3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97496 HNRNPA2B1 Gene This gene is involved in RNA processing and transport. HNRNPA2B1 | gene_symbol || HNRNPA2B1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97499 ERC1 Gene This gene plays a role in signaling. ERC1 | gene_symbol || ERC1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97504 ARHGAP26 Gene This gene plays a role in signal transduction. ARHGAP26 | gene_symbol || ARHGAP26 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97516 ELL Gene This gene is involved in the modulation of transcription. ELL | gene_symbol || ELL | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97519 ACSL6 Gene This gene is involved in the biosynthesis of lipids. ACSL6 | gene_symbol || ACSL6 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97522 GMPS Gene This gene plays a role in nucleotide biosynthesis. GMPS | gene_symbol || GMPS | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97525 GPHN Gene This gene is involved in vitamin metabolism. GPHN | gene_symbol || GPHN | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97528 CLP1 Gene This gene plays a role in RNA processing. CLP1 | gene_symbol || CLP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97531 SPECC1 Gene This gene may be involved in nuclear structure. SPECC1 | gene_symbol || SPECC1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97534 HERPUD1 Gene This gene is involved in the response to endoplasmic reticulum stress. HERPUD1 | gene_symbol || HERPUD1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97537 HIP1 Gene This gene plays a role in both vesicle coat formation and endocytosis. HIP1 | gene_symbol || HIP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97540 FNBP1 Gene This gene plays a role in endocytosis. FNBP1 | gene_symbol || FNBP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97543 GOLGA5 Gene This gene is involved in Golgi maintenance. GOLGA5 | gene_symbol || GOLGA5 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97546 GOPC Gene This gene plays a role in protein transport. GOPC | gene_symbol || GOPC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97549 FOXP1 Gene This gene is involved in transcriptional modulation. FOXP1 | gene_symbol || FOXP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97552 GATA2 Gene This gene is involved in both DNA binding and transcriptional regulation. GATA2 | gene_symbol || GATA2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97556 HLF Gene This gene is involved in both transcriptional regulation and DNA binding. HLF | gene_symbol || HLF | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97559 MNX1 Gene This gene plays a role in both the regulation of transcription and DNA binding. MNX1 | gene_symbol || MNX1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97562 GAS7 Gene This gene may play a role in neuronal development. GAS7 | gene_symbol || GAS7 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97568 HOXA11 Gene This gene is involved in embryologic pattern formation. HOXA11 | gene_symbol || HOXA11 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97571 HOXA13 Gene This gene plays a role in transcriptional modulation. HOXA13 | gene_symbol || HOXA13 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97574 HOXC11 Gene This gene is involved in embryological development. HOXC11 | gene_symbol || HOXC11 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97577 HOXC13 Gene This gene plays a role in the modulation of transcription. HOXC13 | gene_symbol || HOXC13 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97580 HOXD11 Gene This gene is involved in limb morphogenesis. HOXD11 | gene_symbol || HOXD11 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97583 HOXD13 Gene This gene plays a role in the development of limbs and appendages. HOXD13 | gene_symbol || HOXD13 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97586 HSP90AA1 Gene This gene is involved in both protein folding and nitric oxide metabolism. HSP90AA1 | gene_symbol || HSP90AA1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97589 HSP90AB1 Gene This gene plays a role in both interferon signaling and protein folding. HSP90AB1 | gene_symbol || HSP90AB1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97592 FCRL4 Gene This gene may be involved in B cell receptor signaling. FCRL4 | gene_symbol || FCRL4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97595 KDM5A Gene This gene plays a role in transcriptional modulation. KDM5A | gene_symbol || KDM5A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97598 KDM5C Gene This gene is involved in histone modification. KDM5C | gene_symbol || KDM5C | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97601 KTN1 Gene This gene plays a role in kinesin function. KTN1 | gene_symbol || KTN1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97604 LASP1 Gene This gene is involved in actin-dependent ion transport. LASP1 | gene_symbol || LASP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97607 LHFPL6 Gene This gene may play a role in cell adhesion or cell proliferation. LHFP | gene_symbol || LHFP | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97610 LPP Gene This gene may be involved in cell shape and cell motility. LPP | gene_symbol || LPP | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97615 MDS2 Gene This gene plays a role in myelodysplastic syndrome. MDS2 | gene_symbol || MDS2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97618 MN1 Gene This gene is involved in tumor suppression. MN1 | gene_symbol || MN1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97621 MSN Gene This gene plays a role in both cell adhesion and cytoskeleton modeling. MSN | gene_symbol || MSN | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97646 MYH9 Gene This gene is involved in both cytoskeleton modeling and cytokinesis. MYH9 | gene_symbol || MYH9 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97650 MLF1 Gene This gene plays a role in both transcriptional regulation and cell cycle arrest. MLF1 | gene_symbol || MLF1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97653 NACA Gene This gene plays a role in protein sorting. NACA | gene_symbol || NACA | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97668 NIN Gene This gene is involved in the localization of the centrosome. NIN | gene_symbol || NIN | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97671 MAFB Gene This gene plays a role in both hematopoiesis and transcriptional modulation. MAFB | gene_symbol || MAFB | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97674 MAP2K4 Gene This gene is involved in MAPK signaling. MAP2K4 | gene_symbol || MAP2K4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97677 NOTCH2 Gene This gene plays a role in cell-cell signaling. NOTCH2 | gene_symbol || NOTCH2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97680 OMD Gene This gene is involved in cell adhesion. OMD | gene_symbol || OMD | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97683 P2RY8 Gene This gene plays a role in signaling. P2RY8 | gene_symbol || P2RY8 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97687 PAX8 Gene This gene is involved in thyroid development and transcriptional regulation. PAX8 | gene_symbol || PAX8 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97718 PDE4DIP Gene This gene plays a role in protein complex localization. PDE4DIP | gene_symbol || PDE4DIP | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97721 PER1 Gene This gene is involved in circadian rhythm. PER1 | gene_symbol || PER1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97724 PHOX2B Gene This gene plays a role in the regulation of transcription. PHOX2B | gene_symbol || PHOX2B | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97727 SEPTIN5 Gene This gene plays a role in cell division. SEPT5 | gene_symbol || SEPT5 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97730 POU2AF1 Gene This gene is involved in both humoral immunity and transcriptional regulation. POU2AF1 | gene_symbol || POU2AF1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97733 PIK3R1 Gene This gene is involved in phosphoinositol signaling. PIK3R1 | gene_symbol || PIK3R1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97736 PRDM16 Gene This gene plays a role in both transcriptional regulation and adipocyte differentiation. PRDM16 | gene_symbol || PRDM16 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97739 PRF1 Gene This gene is involved in cytolysis. PRF1 | gene_symbol || PRF1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97742 PRKAR1A Gene This gene plays a role in the regulation of protein kinase A. PRKAR1A | gene_symbol || PRKAR1A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97751 RABEP1 Gene This gene is involved in the regulation of both GTPase activity and endocytosis. RABEP1 | gene_symbol || RABEP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97758 RAP1GDS1 Gene This gene is involved in guanine nucleotide exchange. RAP1GDS1 | gene_symbol || RAP1GDS1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97761 RPL22 Gene This gene is involved in translation. RPL22 | gene_symbol || RPL22 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97764 SNX29 Gene This gene may be involved in signal transduction or lipid binding. SNX29 | gene_symbol || SNX29 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97767 SBDS Gene This gene plays a role in ribosome formation. SBDS | gene_symbol || SBDS | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97770 SDHAF2 Gene This gene is involved in the electron transport chain. SDHAF2 | gene_symbol || SDHAF2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97773 SDHB Gene This gene plays a role in electron transport in the mitochondria. SDHB | gene_symbol || SDHB | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97776 SDHC Gene This gene is involved in mitochondrial electron transport. SDHC | gene_symbol || SDHC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97779 SDHD Gene This gene plays a role in the localization of succinate dehydrogenase activity. SDHD | gene_symbol || SDHD | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97782 SEPTIN6 Gene This gene is involved in both cytokinesis and the organization of the actin cytoskeleton. SEPT6 | gene_symbol || SEPT6 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97785 SRSF3 Gene This gene plays a role in RNA splicing and export. SRSF3 | gene_symbol || SRSF3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97788 SH3GL1 Gene This gene may be involved in endocytosis. SH3GL1 | gene_symbol || SH3GL1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97791 SLC45A3 Gene This gene plays a role in transmembrane transport. SLC45A3 | gene_symbol || SLC45A3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97794 SOCS1 Gene This gene is involved in the attenuation of cytokine signaling. SOCS1 | gene_symbol || SOCS1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97797 SRGAP3 Gene This gene plays a role in GTPase-mediated signaling. SRGAP3 | gene_symbol || SRGAP3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97800 SS18 Gene This gene is involved in transcriptional activation. SS18 | gene_symbol || SS18 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97803 SS18L1 Gene This gene plays a role in the positive regulation of transcription. SS18L1 | gene_symbol || SS18L1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97806 SSX1 Gene This gene may be involved in the regulation of transcription. SSX1 | gene_symbol || SSX1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97809 SSX2 Gene This gene may play a role in transcriptional regulation. SSX2 | gene_symbol || SSX2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97814 SSX4 Gene This gene may be involved in transcriptional modulation. SSX4 | gene_symbol || SSX4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97819 SUFU Gene This gene plays a role in the regulation of both transcription and signaling. SUFU | gene_symbol || SUFU | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97822 TCEA1 Gene This gene is involved in transcription. TCEA1 | gene_symbol || TCEA1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97825 HNF1A Gene This gene plays a role in both DNA binding and transcriptional modulation. HNF1A | gene_symbol || HNF1A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97828 TCF12 Gene This gene is involved in both transcriptional regulation and tissue differentiation. TCF12 | gene_symbol || TCF12 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97834 TFG Gene This gene is involved in signaling. TFG | gene_symbol || TFG | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97837 TFPT Gene This gene plays a role in the regulation of apoptosis. TFPT | gene_symbol || TFPT | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97840 THRAP3 Gene This gene is involved in the activation of transcription. THRAP3 | gene_symbol || THRAP3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97843 TNFRSF14 Gene This gene plays a role in receptor signaling. TNFRSF14 | gene_symbol || TNFRSF14 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97846 TNFRSF17 Gene This gene is involved in the modulation of cytokine signaling. TNFRSF17 | gene_symbol || TNFRSF17 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97849 TPM3 Gene This gene plays a role in muscle contraction. TPM3 | gene_symbol || TPM3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97852 TPM4 Gene This gene is involved in smooth muscle cell contraction. TPM4 | gene_symbol || TPM4 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97855 TPR Gene This gene plays a role in both nuclear transport and mitosis. TPR | gene_symbol || TPR | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97858 TRIM33 Gene This gene is involved in the mediation of protein ubiquitination. TRIM33 | gene_symbol || TRIM33 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97861 TRIP11 Gene This gene plays a role in thyroid receptor binding. TRIP11 | gene_symbol || TRIP11 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97867 WIF1 Gene This gene plays a role in Wnt protein-dependent signaling. WIF1 | gene_symbol || WIF1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97870 XPC Gene This gene is involved in nucleotide excision repair. XPC | gene_symbol || XPC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97873 ZMYM2 Gene This gene plays a role in transcriptional modulation. ZNF198 | gene_symbol || ZNF198 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97876 PATZ1 Gene This gene is involved in transcriptional regulation. PATZ1 | gene_symbol || PATZ1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97879 ZNF331 Gene This gene plays a role in transcriptional regulation. ZNF331 | gene_symbol || ZNF331 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97882 ZNF384 Gene This gene is involved in both transcriptional regulation and DNA binding. ZNF384 | gene_symbol || ZNF384 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97885 ZNF521 Gene This gene plays a role in both the positive and negative regulation of transcription. ZNF521 | gene_symbol || ZNF521 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97888 CNBP Gene This gene is involved in sterol-mediated transcription. CNBP | gene_symbol || CNBP | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97891 CNTRL Gene This gene plays a role in cell cycle progression. CNTRL | gene_symbol || CNTRL | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97894 PAFAH1B2 Gene This gene is involved in lipid metabolism. PAFAH1B2 | gene_symbol || PAFAH1B2 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97897 SEPTIN9 Gene This gene plays a role in actin filament dynamics. SEPT9 | gene_symbol || SEPT9 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97900 PCM1 Gene This gene is involved in centrosome formation. PCM1 | gene_symbol || PCM1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C97912 CIC Gene This gene is involved in the modulation of transcription. CIC | gene_symbol || CIC | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C98017 KIAA1549 Gene This gene may play a role in brain functions. KIAA1549 | gene_symbol || KIAA1549 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C98030 PRRX1 Gene This gene plays a role in both transcriptional regulation and muscle cell development. PRRX1 | gene_symbol || PRRX1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C98093 HMGN2P46 Gene This gene may be involved in prostate functions. HMGN2P46 | gene_symbol || HMGN2P46 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C98096 C15orf65 Gene This gene has no known function. C15orf65 | gene_symbol || C15orf65 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C98099 TLX3 Gene This gene may be involved in transcriptional regulation. TLX3 | gene_symbol || TLX3 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C98120 FEN1 Gene This gene is involved in DNA replication and repair. FEN1 | gene_symbol || FEN1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C98146 GRIN2A Gene This gene is involved in the regulation of ion transport. GRIN2A | gene_symbol || GRIN2A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C98210 MED12 Gene This gene plays a role in the regulation of RNA polymerase II-dependent transcription. MED12 | gene_symbol || MED12 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C98284 SF3B1 Gene This gene is involved in mRNA splicing. SF3B1 | gene_symbol || SF3B1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C99462 VTI1A Gene This gene is involved in vesicular transport. VTI1A | gene_symbol || VTI1A | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C99484 XPO1 Gene This gene plays a role in the regulation of nuclear export. XPO1 | gene_symbol || XPO1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C99614 FUBP1 Gene This gene plays a role in transcriptional modulation. FUBP1 | gene_symbol || FUBP1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol C C177537 GDC Value Terminology C99663 RAC1 Gene This gene is involved in both cell motility and signal transduction. RAC1 | gene_symbol || RAC1 | second_gene_symbol C171253 || C173595 second_gene_symbol || gene_symbol D C177537 GDC Value Terminology C113120 Hepatitis C RNA Measurement A measurement of the Hepatitis C RNA in a biological specimen. Hepatitis C Virus RNA | viral_hepatitis_serologies C177609 viral_hepatitis_serologies D C177537 GDC Value Terminology C116400 Hepatitis C Antibody An antibody produced by B-lymphocytes in response to hepatitis C virus infection. Hepatitis C Antibody | viral_hepatitis_serologies C177609 viral_hepatitis_serologies D C177537 GDC Value Terminology C156773 EGFR Mutant-specific Inhibitor D-0316 An orally available inhibitor of the epidermal growth factor receptor (EGFR) mutant form T790M, with potential antineoplastic activity. Upon administration, the EGFR mutant-specific inhibitor D-0316 specifically binds to and inhibits EGFR T790M, a secondarily acquired resistance mutation, which prevents EGFR-mediated signaling and leads to cell death in EGFR T790M-expressing tumor cells. Compared to some other EGFR inhibitors, D-0316 may have therapeutic benefits in tumors with T790M-mediated drug resistance. EGFR, a receptor tyrosine kinase that is mutated in many tumor cell types, plays a key role in tumor cell proliferation and tumor vascularization. EGFR Mutant-specific Inhibitor D-0316 | therapeutic_agents C1909 therapeutic_agents D C177537 GDC Value Terminology C62786 Hepatitis B Virus HBsAg Surface Protein Antigen Any one of the hepatitis B antigens found on the surface of the Dane particle and on the 20 nm spherical and tubular particles. Several subspecificities of the surface antigen are known. These were formerly called the Australia antigen. Hepatitis B Surface Antigen | viral_hepatitis_serologies C177609 viral_hepatitis_serologies D C177537 GDC Value Terminology C62796 Hepatitis B Virus Surface Antibody An antibody produced by B lymphocytes to the hepatitis B surface antigen as part of the immune response to hepatitis B viral infection. HBV Surface Antibody | viral_hepatitis_serologies C177609 viral_hepatitis_serologies D C177537 GDC Value Terminology C62797 Hepatitis B Virus Core Antibody An antibody produced by B lymphocytes to the hepatitis B core antigen as part of the immune response to hepatitis B viral infection. HBV Core Antibody | viral_hepatitis_serologies C177609 viral_hepatitis_serologies D C177537 GDC Value Terminology C71104 Clinical Trial A research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes. Clinical Trial | therapeutic_agents C1909 therapeutic_agents D C177537 GDC Value Terminology C8510 Progressive Neoplastic Disease PD-Progressive Disease | best_overall_response || PD-Progressive Disease | disease_response C50995 || C94536 disease_response || best_overall_response