Release Date	Request Code	Change Type	NCI Code	CDISC Term Type	CDISC Codelist (Short Name)	CDISC Codelist (Long Name)	Change Summary	Original	New	Change Implementation Instructions

2025-03-28	CDISC-6662	Add	C214529	Term	FRM	Dosage Form	Add new term to existing codelist	- - -	TABLET, MODIFIED RELEASE, BILAYER	

2025-03-28	CDISC-6499	Add	C214660	Term	FRM	Dosage Form	Add new term to existing codelist	- - -	TABLET, GASTRORETENTIVE	

2025-03-28	CDISC-6519	Add	C214661	Term	FRM	Dosage Form	Add new term to existing codelist	- - -	TABLET, MODIFIED RELEASE, MATRIX	

2025-03-28	CDISC-6519	Add	C214662	Term	FRM	Dosage Form	Add new term to existing codelist	- - -	TABLET, MODIFIED RELEASE, EXTRUDABLE CORE SYSTEM	

2025-03-28	CDISC-6519	Add	C214663	Term	FRM	Dosage Form	Add new term to existing codelist	- - -	TABLET, MODIFIED RELEASE, BILAYER (1:2)	

2025-03-28	CDISC-6519	Add	C214664	Term	FRM	Dosage Form	Add new term to existing codelist	- - -	TABLET, MODIFIED RELEASE, BILAYER (1:1)	

2025-03-28	CDISC-6551	Add	C214665	Term	FRM	Dosage Form	Add new term to existing codelist	- - -	NANOSUSPENSION	

2025-03-28	CDISC-6487	Add	C166073	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Granzyme B	

2025-03-28	CDISC-6662	Add	C213922	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Casts	

2025-03-28	CDISC-6662	Add	C213923	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Crystals	

2025-03-28	CDISC-6662	Add	C213924	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Ammonium Oxalate Crystals	

2025-03-28	CDISC-6462	Add	C214675	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Interleukin 17C	

2025-03-28	CDISC-6662	Add	C214676	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Glucuronidated Bilirubin	

2025-03-28	CDISC-6662	Add	C214677	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Delta Bilirubin	

2025-03-28	CDISC-6482	Add	C214678	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Gluten Immunogenic Peptide	

2025-03-28	CDISC-6019	Add	C214679	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	GFR, Estimated Non-Indexed	

2025-03-28	CDISC-6662	Add	C214680	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	GFR, Estimated Indexed	

2025-03-28	CDISC-6662	Add	C214681	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	GFR from B-2 Microglobulin Adj for aBSA	

2025-03-28	CDISC-6662	Add	C214682	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	GFR from Beta-Trace Protein Adj for aBSA	

2025-03-28	CDISC-6662	Add	C214683	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	GFR from Cystatin C and Creat Adj aBSA	

2025-03-28	CDISC-6662	Add	C214684	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	GFR from Creat and UreaN Adj aBSA	

2025-03-28	CDISC-6662	Add	C214685	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	GFR from Creat,UreaN,Alb Adj aBSA	

2025-03-28	CDISC-6662	Add	C214686	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	GFR from Creatinine Adjusted for aBSA	

2025-03-28	CDISC-6662	Add	C214687	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	GFR from Cystatin C Adjusted for aBSA	

2025-03-28	CDISC-6491	Add	C214688	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Clot Firmness	

2025-03-28	CDISC-6491	Add	C214689	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Clot Formation Time	

2025-03-28	CDISC-6491	Add	C214690	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Clot Initiation Time	

2025-03-28	CDISC-6491	Add	C214691	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Maximum Clot Firmness	

2025-03-28	CDISC-6491	Add	C214692	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Clot Lysis Index	

2025-03-28	CDISC-6662	Add	C214693	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Maximum Clot Lysis	

2025-03-28	CDISC-6662	Add	C214694	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Clot Formation Alpha Angle	

2025-03-28	CDISC-6487	Add	C166073	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	GZMB	

2025-03-28	CDISC-6662	Add	C213922	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	CASTS	

2025-03-28	CDISC-6662	Add	C213923	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	CRYSTALS	

2025-03-28	CDISC-6662	Add	C213924	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	CYAMMOX	

2025-03-28	CDISC-6462	Add	C214675	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	INTLK17C	

2025-03-28	CDISC-6662	Add	C214676	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	BILGLC	

2025-03-28	CDISC-6662	Add	C214677	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	BILDELTA	

2025-03-28	CDISC-6482	Add	C214678	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	GLUTENIP	

2025-03-28	CDISC-6019	Add	C214679	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	GFRENI	

2025-03-28	CDISC-6662	Add	C214680	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	GFREI	

2025-03-28	CDISC-6662	Add	C214681	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	GFRNIB2M	

2025-03-28	CDISC-6662	Add	C214682	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	GFRNIBTP	

2025-03-28	CDISC-6662	Add	C214683	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	GFRNICCC	

2025-03-28	CDISC-6662	Add	C214684	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	GFRNICU	

2025-03-28	CDISC-6662	Add	C214685	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	GFRNICUA	

2025-03-28	CDISC-6662	Add	C214686	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	GFRNICRT	

2025-03-28	CDISC-6662	Add	C214687	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	GFRNICYC	

2025-03-28	CDISC-6491	Add	C214688	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	CLOTFM	

2025-03-28	CDISC-6491	Add	C214689	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	CLOTFTIM	

2025-03-28	CDISC-6491	Add	C214690	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	CLOTITIM	

2025-03-28	CDISC-6491	Add	C214691	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	CLOTFMMX	

2025-03-28	CDISC-6491	Add	C214692	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	CLOTLYIX	

2025-03-28	CDISC-6662	Add	C214693	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	CLOTLYMX	

2025-03-28	CDISC-6662	Add	C214694	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	CLOTFAA	

2025-03-28	CDISC-6371	Add	C214695	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	PORTAL VEIN, LEFT BRANCH	

2025-03-28	CDISC-6373	Add	C214696	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	PORTAL VEIN, RIGHT BRANCH	

2025-03-28	CDISC-6444	Add	C214697	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	ELBOW JOINT TENDONS	

2025-03-28	CDISC-6444	Add	C214698	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	BICEPS BRACHII TENDONS	

2025-03-28	CDISC-6569	Add	C214699	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	INTRARETINAL SPACE	

2025-03-28	CDISC-6569	Add	C214700	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	SUBRETINAL SPACE	

2025-03-28	CDISC-6662	Add	C38936	Term	NEOPLASM	Neoplasm Type	Add new term to existing codelist	- - -	MENINGIOMA, BENIGN	NCI C-code updated from C4055 to C38936

2025-03-28	CDISC-6662	Add	C6510	Term	NEOPLASM	Neoplasm Type	Add new term to existing codelist	- - -	LEIOMYOMA, BENIGN	NCI C-code updated from C3157 to C6510

2025-03-28	CDISC-6662	Add	C9303	Term	NEOPLASM	Neoplasm Type	Add new term to existing codelist	- - -	MAST CELL TUMOR, BENIGN	NCI C-code updated from C3217 to C9303

2025-03-28	CDISC-6662	Add	C213929	Term	NONNEO	Non-Neoplastic Finding Type	Add new term to existing codelist	- - -	CALLUS	NCI C-code updated from C79624 to C213929

2025-03-28	CDISC-6428	Add	C214764	Term	NONNEO	Non-Neoplastic Finding Type	Add new term to existing codelist	- - -	RETINAL DYSPLASIA	

2025-03-28	CDISC-6460	Add	C214765	Term	NONNEO	Non-Neoplastic Finding Type	Add new term to existing codelist	- - -	C-CELL COMPLEX	

2025-03-28	CDISC-6461	Add	C214766	Term	NONNEO	Non-Neoplastic Finding Type	Add new term to existing codelist	- - -	GLOMERULUS, IMMATURE	

2025-03-28	CDISC-6508	Add	C214767	Term	NONNEO	Non-Neoplastic Finding Type	Add new term to existing codelist	- - -	MYELOID TO ERYTHROID RATIO, INCREASED	

2025-03-28	CDISC-6508	Add	C214768	Term	NONNEO	Non-Neoplastic Finding Type	Add new term to existing codelist	- - -	MYELOID TO ERYTHROID RATIO, DECREASED	

2025-03-28	CDISC-6662	Add	C214769	Term	NONNEO	Non-Neoplastic Finding Type	Add new term to existing codelist	- - -	INTRAMURAL PLAQUE, FATTY	

2025-03-28	CDISC-6662	Add	C214770	Term	NONNEO	Non-Neoplastic Finding Type	Add new term to existing codelist	- - -	PROLIFERATION, EXTRA-ISLET ENDOCRINE CELL	

2025-03-28	CDISC-6662	Add	C34513	Term	NONNEO	Non-Neoplastic Finding Type	Add new term to existing codelist	- - -	DYSTROPHY, CORNEA	

2025-03-28	CDISC-6662	Add	C35768	Term	NONNEO	Non-Neoplastic Finding Type	Add new term to existing codelist	- - -	ATHEROSCLEROSIS	

2025-03-28	CDISC-6342	Add	C214735	Term	PKUDMG	PK Units of Measure - Dose mg	Add new term to existing codelist	- - -	h*nmolEq/L/mg	

2025-03-28	CDISC-6344	Add	C214737	Term	PKUDMG	PK Units of Measure - Dose mg	Add new term to existing codelist	- - -	nmolEq/L/mg	

2025-03-28	CDISC-6341	Add	C214734	Term	PKUDUG	PK Units of Measure - Dose ug	Add new term to existing codelist	- - -	h*nmolEq/L/ug	

2025-03-28	CDISC-6343	Add	C214736	Term	PKUDUG	PK Units of Measure - Dose ug	Add new term to existing codelist	- - -	nmolEq/L/ug	

2025-03-28	CDISC-6337	Add	C214731	Term	PKUNIT	PK Units of Measure	Add new term to existing codelist	- - -	nmolEq/L	

2025-03-28	CDISC-6338	Add	C214732	Term	PKUNIT	PK Units of Measure	Add new term to existing codelist	- - -	nmolEq/kg	

2025-03-28	CDISC-6340	Add	C214733	Term	PKUNIT	PK Units of Measure	Add new term to existing codelist	- - -	h*nmolEq/L	

2025-03-28	CDISC-6341	Add	C214734	Term	PKUNIT	PK Units of Measure	Add new term to existing codelist	- - -	h*nmolEq/L/ug	

2025-03-28	CDISC-6342	Add	C214735	Term	PKUNIT	PK Units of Measure	Add new term to existing codelist	- - -	h*nmolEq/L/mg	

2025-03-28	CDISC-6343	Add	C214736	Term	PKUNIT	PK Units of Measure	Add new term to existing codelist	- - -	nmolEq/L/ug	

2025-03-28	CDISC-6344	Add	C214737	Term	PKUNIT	PK Units of Measure	Add new term to existing codelist	- - -	nmolEq/L/mg	

2025-03-28	CDISC-6474	Add	C214763	Term	SPEC	Specimen	Add new term to existing codelist	- - -	GANGLION, CILIARY	

2025-03-28	CDISC-6554	Add	C122632	Term	UNIT	Unit	Add new term to existing codelist	- - -	INJECTION	

2025-03-28	CDISC-6409	Add	C214756	Term	UNIT	Unit	Add new term to existing codelist	- - -	mmHg*m2/L/min	

2025-03-28	CDISC-6456	Add	C214757	Term	UNIT	Unit	Add new term to existing codelist	- - -	SFC/WELL	

2025-03-28	CDISC-6456	Add	C214758	Term	UNIT	Unit	Add new term to existing codelist	- - -	/WELL	

2025-03-28	CDISC-6485	Add	C214759	Term	UNIT	Unit	Add new term to existing codelist	- - -	/um2	

2025-03-28	CDISC-6529	Add	C214760	Term	UNIT	Unit	Add new term to existing codelist	- - -	mmol/kg/s	

2025-03-28	CDISC-6496	Add	C214761	Term	UNIT	Unit	Add new term to existing codelist	- - -	ABC	

2025-03-28	CDISC-6476	Add	C214762	Term	VSTEST	Vital Signs Test Name	Add new term to existing codelist	- - -	Fetal Size-for-Gestational Age Category	

2025-03-28	CDISC-6476	Add	C214762	Term	VSTESTCD	Vital Signs Test Code	Add new term to existing codelist	- - -	FTSZGAC	

2025-03-28	CDISC-6595	Remove	C103406	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Human Anti-Mouse Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C103418	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Myelin Antibodies	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C116207	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Parietal Cell Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C116210	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Panel Reactive Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C120626	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Anti-Neutrophil Cytoplasmic Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128953	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	HLA-A23 Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128954	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	HLA-A2 Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128959	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	HLA-DR51 Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128960	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	HLA-DR52 Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128961	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	HLA-DR53 Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128964	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	HLA Class I Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128965	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	HLA Class II Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128966	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	HLA Class II Panel Reactive Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128967	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	HLA Class I Panel Reactive Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C132381	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Calculated Panel Reactive Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C147300	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Neutrophil Cytoplasmic Ab, Atypical	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C147301	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Neutrophil Cytoplasmic Ab, Classic	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C147302	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Neutrophil Cytoplasmic Ab, Perinuclear	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C147334	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Endomysial IgA Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C163420	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Anti-Neutrophil Cytoplasmic IgG Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C163432	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Endomysial Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C163465	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Mitochondrial M2 IgG Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C163496	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Tissue Transglutaminase IgG Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C165965	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Human Anti-Human Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C176313	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Anti-Neutrophil Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6662	Remove	C74673	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Crystals	- - -	NCI C-code updated from C74673 to C213923

2025-03-28	CDISC-6662	Remove	C74759	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Ammonium Oxalate Crystals	- - -	NCI C-code updated from C74759 to C213924

2025-03-28	CDISC-6662	Remove	C74763	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Casts	- - -	NCI C-code updated from C74763 to C213922

2025-03-28	CDISC-6595	Remove	C81979	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Beta-2 Glycoprotein Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C81987	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Islet Neogenesis Assoc Protein Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C98740	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Human Anti-Sheep IgE Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C98741	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Human Anti-Sheep IgG Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C98742	Term	LBTEST	Laboratory Test Name	Remove term entirely from codelist	Human Anti-Sheep IgM Antibody	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C103406	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	HAMAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C103418	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	MYELINAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C116207	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	PARICEAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C116210	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	PRAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C120626	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	ANCAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128953	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	HLAA23A	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128954	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	HLAA2AB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128959	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	HLADR51A	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128960	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	HLADR52A	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128961	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	HLADR53A	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128964	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	HLAIAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128965	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	HLAIIAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128966	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	HLAIIPRA	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C128967	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	HLAIPRA	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C132381	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	PRABC	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C147300	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	ANCATYAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C147301	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	ANCCLSAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C147302	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	ANCPNCAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C147334	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	EDMIGAAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C163420	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	ANCIGAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C163432	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	EDMAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C163465	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	MM2IGAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C163496	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	TTGIGGAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C165965	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	HAHA	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C176313	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	ANAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6662	Remove	C74673	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	CRYSTALS	- - -	NCI C-code updated from C74673 to C213923

2025-03-28	CDISC-6662	Remove	C74759	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	CYAMMOX	- - -	NCI C-code updated from C74759 to C213924

2025-03-28	CDISC-6662	Remove	C74763	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	CASTS	- - -	NCI C-code updated from C74763 to C213922

2025-03-28	CDISC-6595	Remove	C81979	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	B2GLYAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C81987	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	INGAPAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C98740	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	HASIGEAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C98741	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	HASIGGAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6595	Remove	C98742	Term	LBTESTCD	Laboratory Test Code	Remove term entirely from codelist	HASIGMAB	- - -	These TESTs are re-modeled in the IS domain. Please see the IS codetable mapping file for how to model this data.

2025-03-28	CDISC-6662	Remove	C3157	Term	NEOPLASM	Neoplasm Type	Remove term entirely from codelist	LEIOMYOMA, BENIGN	- - -	NCI C-code updated from C3157 to C6510

2025-03-28	CDISC-6662	Remove	C3217	Term	NEOPLASM	Neoplasm Type	Remove term entirely from codelist	MAST CELL TUMOR, BENIGN	- - -	NCI C-code updated from C3217 to C9303

2025-03-28	CDISC-6662	Remove	C4055	Term	NEOPLASM	Neoplasm Type	Remove term entirely from codelist	MENINGIOMA, BENIGN	- - -	NCI C-code updated from C4055 to C38936

2025-03-28	CDISC-6662	Remove	C79624	Term	NONNEO	Non-Neoplastic Finding Type	Remove term entirely from codelist	CALLUS	- - -	NCI C-code updated from C79624 to C213929

2025-03-28	CDISC-6662	Update	C102709	CDISC Definition	EGSTRESC	ECG Result	Update CDISC Definition	An electrocardiographic finding of a QT interval corrected for heart rate that is shorter than the lower limit of normal. Thresholds for different age, gender, and patient populations exist.	An electrocardiographic finding of a QT interval corrected for heart rate that is shorter than the lower limit of normal. Thresholds for different age, sex, and patient populations exist.	

2025-03-28	CDISC-6662	Update	C107098	CDISC Definition	EGSTRESC	ECG Result	Update CDISC Definition	An electrocardiographic finding in which the QT interval corrected for heart rate using Bazett's formula is prolonged. Thresholds for different age, gender, and patient populations exist.	An electrocardiographic finding in which the QT interval corrected for heart rate using Bazett's formula is prolonged. Thresholds for different age, sex, and patient populations exist.	

2025-03-28	CDISC-6662	Update	C107099	CDISC Definition	EGSTRESC	ECG Result	Update CDISC Definition	An electrocardiographic finding in which the QT interval corrected for heart rate using Fridericia's formula is prolonged. Thresholds for different age, gender, and patient populations exist.	An electrocardiographic finding in which the QT interval corrected for heart rate using Fridericia's formula is prolonged. Thresholds for different age, sex, and patient populations exist.	

2025-03-28	CDISC-6662	Update	C111097	CDISC Definition	EGSTRESC	ECG Result	Update CDISC Definition	An electrocardiographic finding of abnormally slow heart rate with its origin in the sinus node. Thresholds for different age, gender, and patient populations exist.	An electrocardiographic finding of abnormally slow heart rate with its origin in the sinus node. Thresholds for different age, sex, and patient populations exist.	

2025-03-28	CDISC-6662	Update	C111104	CDISC Definition	EGSTRESC	ECG Result	Update CDISC Definition	An electrocardiographic finding of abnormally rapid heart rate with its origin in the sinus node. Thresholds for different age, gender, and patient populations exist.	An electrocardiographic finding of abnormally rapid heart rate with its origin in the sinus node. Thresholds for different age, sex, and patient populations exist.	

2025-03-28	CDISC-6662	Update	C111120	CDISC Definition	EGSTRESC	ECG Result	Update CDISC Definition	An electrocardiographic finding of abnormally slow heart rate. Thresholds for different age, gender, and patient populations exist.	An electrocardiographic finding of abnormally slow heart rate. Thresholds for different age, sex, and patient populations exist.	

2025-03-28	CDISC-6662	Update	C111121	CDISC Definition	EGSTRESC	ECG Result	Update CDISC Definition	An electrocardiographic finding of abnormally rapid heart rate. Thresholds for different age, gender, and patient populations exist.	An electrocardiographic finding of abnormally rapid heart rate. Thresholds for different age, sex, and patient populations exist.	

2025-03-28	CDISC-6662	Update	C112402	CDISC Definition	EGSTRESC	ECG Result	Update CDISC Definition	An electrocardiographic finding in which the QT interval corrected for heart rate using Bazett's formula is shortened. Thresholds for different age, gender, and patient populations exist.	An electrocardiographic finding in which the QT interval corrected for heart rate using Bazett's formula is shortened. Thresholds for different age, sex, and patient populations exist.	

2025-03-28	CDISC-6662	Update	C112403	CDISC Definition	EGSTRESC	ECG Result	Update CDISC Definition	An electrocardiographic finding in which the QT interval corrected for heart rate using Fridericia's formula is shortened. Thresholds for different age, gender, and patient populations exist.	An electrocardiographic finding in which the QT interval corrected for heart rate using Fridericia's formula is shortened. Thresholds for different age, sex, and patient populations exist.	

2025-03-28	CDISC-6662	Update	C62246	CDISC Definition	EGSTRESC	ECG Result	Update CDISC Definition	An electrocardiographic finding of an abnormally short PR interval. Thresholds for different age, gender, and patient populations exist.	An electrocardiographic finding of an abnormally short PR interval. Thresholds for different age, sex, and patient populations exist.	

2025-03-28	CDISC-6662	Update	C71034	CDISC Definition	EGSTRESC	ECG Result	Update CDISC Definition	An electrocardiographic finding in which the QT interval not corrected for heart rate is prolonged. Thresholds for different age, gender, and patient populations exist.	An electrocardiographic finding in which the QT interval not corrected for heart rate is prolonged. Thresholds for different age, sex, and patient populations exist.	

2025-03-28	CDISC-6662	Update	C83817	CDISC Definition	EGSTRESC	ECG Result	Update CDISC Definition	An electrocardiographic finding in which the QTc interval corrected for heart rate is prolonged. Thresholds for different age, gender, and patient populations exist.	An electrocardiographic finding in which the QTc interval corrected for heart rate is prolonged. Thresholds for different age, sex, and patient populations exist.	

2025-03-28	CDISC-6662	Update	C92228	CDISC Definition	EGSTRESC	ECG Result	Update CDISC Definition	An electrocardiographic finding in which the QT interval corrected for heart rate using Bazett's formula is slightly prolonged. Thresholds for different age, gender, and patient populations exist.	An electrocardiographic finding in which the QT interval corrected for heart rate using Bazett's formula is slightly prolonged. Thresholds for different age, sex, and patient populations exist.	

2025-03-28	CDISC-6662	Update	C92229	CDISC Definition	EGSTRESC	ECG Result	Update CDISC Definition	An electrocardiographic finding in which the QT interval corrected for heart rate using Fridericia's formula is slightly prolonged. Thresholds for different age, gender, and patient populations exist.	An electrocardiographic finding in which the QT interval corrected for heart rate using Fridericia's formula is slightly prolonged. Thresholds for different age, sex, and patient populations exist.	

2025-03-28	CDISC-6662	Update	C42994	CDISC Definition	FRM	Dosage Form	Update CDISC Definition	A liquid dosage form that contains solid particles dispersed in a liquid vehicle. Note: A liquid is pourable; it flows and conforms to its container at room temperature. It displays Newtonian or pseudoplastic flow behavior.	A dosage form that contains solid particles dispersed in a liquid vehicle.	

2025-03-28	CDISC-6662	Update	C100449	CDISC Definition	LBTEST	Laboratory Test Name	Update CDISC Definition	A measurement of the glomerular filtration rate (GFR) based on the clearance of beta-trace protein after adjusting it for the body surface area.	A direct measurement of the glomerular filtration rate (GFR) based on the clearance of beta-trace protein after adjusting it for the standard body surface area value 1.73m2.	

2025-03-28	CDISC-6662	Update	C100449	NCI Preferred Term	LBTEST	Laboratory Test Name	Update NCI Preferred Term	Glomerular Filtration Rate from Beta-Trace Protein Adjusted for BSA Measurement	Direct Glomerular Filtration Rate from Beta-Trace Protein Adjusted for Standard BSA Measurement	

2025-03-28	CDISC-6662	Update	C100450	CDISC Definition	LBTEST	Laboratory Test Name	Update CDISC Definition	A measurement of the glomerular filtration rate (GFR) based on the clearance of beta-2 microglobulin after adjusting it for the body surface area.	A direct measurement of the glomerular filtration rate (GFR) based on the clearance of beta-2 microglobulin after adjusting it for the standard body surface area value 1.73m2.	

2025-03-28	CDISC-6662	Update	C100450	NCI Preferred Term	LBTEST	Laboratory Test Name	Update NCI Preferred Term	Glomerular Filtration Rate from B-2 Microglobulin Adjusted for BSA Measurement	Direct Glomerular Filtration Rate from Beta-Trace Protein Adjusted for Standard BSA Measurement	

2025-03-28	CDISC-6662	Update	C105443	CDISC Definition	LBTEST	Laboratory Test Name	Update CDISC Definition	A biomarker test that measures liver pathology through the assessment of a six-parameter blood test (for Alpha-2-macroglobulin, Haptoglobin, Apolipoprotein A1, Gamma-glutamyl transpeptidase (GGT), Total bilirubin, and Alanine aminotransferase (ALT)), taking into account the age and gender of the patient.	A biomarker test that measures liver pathology through the assessment of a six-parameter blood test (for Alpha-2-macroglobulin, Haptoglobin, Apolipoprotein A1, Gamma-glutamyl transpeptidase (GGT), Total bilirubin, and Alanine aminotransferase (ALT)), taking into account the age and sex of the patient.	

2025-03-28	CDISC-6662	Update	C110935	CDISC Definition	LBTEST	Laboratory Test Name	Update CDISC Definition	A kidney function test that estimates the fluid volume that is filtered from the kidney glomeruli to the Bowman's capsule per unit of time.	A kidney function test that estimates the fluid volume that is filtered from the kidney glomeruli to the Bowman's capsule per unit of time, which may or may not be indexed for body surface area.	

2025-03-28	CDISC-6662	Update	C122157	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	T Cells	

2025-03-28	CDISC-6662	Update	C127614	CDISC Definition	LBTEST	Laboratory Test Name	Update CDISC Definition	An estimation of the glomerular filtration rate adjusted for body surface area based on cystatin C and creatinine.	An estimation of the glomerular filtration rate adjusted for standard body surface area (1.73m2) based on cystatin C and creatinine.	

2025-03-28	N/A	Update	C127614	NCI Preferred Term	LBTEST	Laboratory Test Name	Update NCI Preferred Term	Glomerular Filtration Rate from Cystatin C and Creatinine Adjusted for BSA	Estimated Glomeluar Filtration Rate from Cystatin C and Creatinine Adjusted for Standard BSA	

2025-03-28	CDISC-6662	Update	C128975	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	Plasma Cells/Leuk	

2025-03-28	CDISC-6662	Update	C147351	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	Gran/Leuk	

2025-03-28	CDISC-6662	Update	C147385	CDISC Definition	LBTEST	Laboratory Test Name	Update CDISC Definition	A scoring system that evaluates liver pathology through the assessment of multiple blood test parameters, taking into account additional demographic factors such as the age and/or gender of the subject.	A scoring system that evaluates liver pathology through the assessment of multiple blood test parameters, taking into account additional demographic factors such as the age and/or sex of the subject.	

2025-03-28	N/A	Update	C147404	NCI Preferred Term	LBTEST	Laboratory Test Name	Update NCI Preferred Term	N-methylhistamine Measurement	N-Methylhistamine Measurement	

2025-03-28	CDISC-6662	Update	C163442	CDISC Definition	LBTEST	Laboratory Test Name	Update CDISC Definition	An estimation of the glomerular filtration rate adjusted for body surface area based on creatinine and urea nitrogen.	An estimation of the glomerular filtration rate adjusted for standard body surface area (1.73m2) based on creatinine and urea nitrogen.	

2025-03-28	N/A	Update	C163442	NCI Preferred Term	LBTEST	Laboratory Test Name	Update NCI Preferred Term	Glomerular Filtration Rate from Creatinine and Urea Nitrogen Adjusted for Body Surface Area Measurement	Estimated Glomerular Filtration Rate from Creatinine and Urea Nitrogen Adjusted for Standard BSA	

2025-03-28	CDISC-6662	Update	C163443	CDISC Definition	LBTEST	Laboratory Test Name	Update CDISC Definition	An estimation of the glomerular filtration rate adjusted for body surface area based on creatinine, urea nitrogen, and albumin.	An estimation of the glomerular filtration rate adjusted for standard body surface area (1.73m2) based on creatinine, urea nitrogen, and albumin.	

2025-03-28	N/A	Update	C163443	NCI Preferred Term	LBTEST	Laboratory Test Name	Update NCI Preferred Term	Glomerular Filtration Rate from Creatinine, Urea Nitrogen, and Albumin Adjusted for Body Surface Area Measurement	Estimated Glomerular Filtration Rate from Creatinine, Urea Nitrogen, and Albumin Adjusted for Standard BSA	

2025-03-28	CDISC-6462	Update	C165985	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	Protransforming Growth Factor Alpha	

2025-03-28	CDISC-6462	Update	C165985	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	TGF-Alpha	

2025-03-28	CDISC-6662	Update	C174314	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	B Cells	

2025-03-28	CDISC-6662	Update	C187987	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	Plasma Cells/Total Cells	

2025-03-28	CDISC-6462	Update	C198285	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	C-Type Lectin Domain Family 8 Member A	

2025-03-28	CDISC-6462	Update	C198285	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	CLEC8A	

2025-03-28	CDISC-6462	Update	C198285	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	Oxidized LDL Receptor 1	

2025-03-28	CDISC-6462	Update	C198285	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	Oxidized Low-Density Lipoprotein Receptor 1	

2025-03-28	CDISC-6662	Update	C199902	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	NF-H	

2025-03-28	CDISC-6662	Update	C199902	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	Neurofilament Heavy Polypeptide	

2025-03-28	CDISC-6662	Update	C199902	CDISC Synonym	LBTEST	Laboratory Test Name	Remove CDISC Synonym	Neurofilament Heavy Polypeptide: NF-H	- - -	

2025-03-28	CDISC-6662	Update	C209578	CDISC Submission Value	LBTEST	Laboratory Test Name	Update CDISC Submission Value	Amyloid Probably Score	Amyloid Probability Score	

2025-03-28	CDISC-6662	Update	C209578	CDISC Synonym	LBTEST	Laboratory Test Name	Remove CDISC Synonym	Amyloid Probably Score	- - -	

2025-03-28	CDISC-6662	Update	C64481	CDISC Definition	LBTEST	Laboratory Test Name	Update CDISC Definition	A measurement of the conjugated or water-soluble bilirubin in a biological specimen.	A measurement of the glucuronidated bilirubin and albumin-bound bilirubin in a biological specimen.	

2025-03-28	CDISC-6662	Update	C64481	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	Conjugated Bilirubin + Albumin-Bound Bilirubin	

2025-03-28	CDISC-6662	Update	C64481	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	Conjugated Bilirubin + Delta Bilirubin	

2025-03-28	CDISC-6662	Update	C64483	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	Non-Glucuronidated Bilirubin	

2025-03-28	CDISC-6662	Update	C64483	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	Unconjugated Bilirubin	

2025-03-28	N/A	Update	C64849	NCI Preferred Term	LBTEST	Laboratory Test Name	Update NCI Preferred Term	Glycosylated Hemoglobin Measurement	Hemoglobin A1C Measurement	

2025-03-28	CDISC-6662	Update	C64849	CDISC Synonym	LBTEST	Laboratory Test Name	Remove CDISC Synonym	Glycated Hemoglobin	- - -	

2025-03-28	CDISC-6662	Update	C64849	CDISC Synonym	LBTEST	Laboratory Test Name	Remove CDISC Synonym	Glycosylated Hemoglobin A1C	- - -	

2025-03-28	N/A	Update	C81993	NCI Preferred Term	LBTEST	Laboratory Test Name	Update NCI Preferred Term	Tissue Plasminogen Activator Antigen Measurement	Tissue Plasminogen Activator Measurement	

2025-03-28	CDISC-6662	Update	C98735	CDISC Definition	LBTEST	Laboratory Test Name	Update CDISC Definition	An estimation of the glomerular filtration rate adjusted for body surface area based on creatinine.	An estimation of the glomerular filtration rate adjusted for standard body surface area (1.73m2) based on creatinine.	

2025-03-28	N/A	Update	C98735	NCI Preferred Term	LBTEST	Laboratory Test Name	Update NCI Preferred Term	Glomerular Filtration Rate from Creatinine Adjusted for BSA	Estimated Glomerular Filtration Rate from Creatinine Adjusted for Standard BSA	

2025-03-28	CDISC-6662	Update	C98736	CDISC Definition	LBTEST	Laboratory Test Name	Update CDISC Definition	An estimation of the glomerular filtration rate adjusted for body surface area based on cystatin C.	An estimation of the glomerular filtration rate adjusted for standard body surface area (1.73m2) based on cystatin C.	

2025-03-28	N/A	Update	C98736	NCI Preferred Term	LBTEST	Laboratory Test Name	Update NCI Preferred Term	Glomerular Filtration Rate from Cystatin C Adjusted for BSA	Estimated Glomerular Filtration Rate from Cystatin C Adjusted for Standard BSA	

2025-03-28	CDISC-6662	Update	C100449	CDISC Definition	LBTESTCD	Laboratory Test Code	Update CDISC Definition	A measurement of the glomerular filtration rate (GFR) based on the clearance of beta-trace protein after adjusting it for the body surface area.	A direct measurement of the glomerular filtration rate (GFR) based on the clearance of beta-trace protein after adjusting it for the standard body surface area value 1.73m2.	

2025-03-28	CDISC-6662	Update	C100449	NCI Preferred Term	LBTESTCD	Laboratory Test Code	Update NCI Preferred Term	Glomerular Filtration Rate from Beta-Trace Protein Adjusted for BSA Measurement	Direct Glomerular Filtration Rate from Beta-Trace Protein Adjusted for Standard BSA Measurement	

2025-03-28	CDISC-6662	Update	C100450	CDISC Definition	LBTESTCD	Laboratory Test Code	Update CDISC Definition	A measurement of the glomerular filtration rate (GFR) based on the clearance of beta-2 microglobulin after adjusting it for the body surface area.	A direct measurement of the glomerular filtration rate (GFR) based on the clearance of beta-2 microglobulin after adjusting it for the standard body surface area value 1.73m2.	

2025-03-28	CDISC-6662	Update	C100450	NCI Preferred Term	LBTESTCD	Laboratory Test Code	Update NCI Preferred Term	Glomerular Filtration Rate from B-2 Microglobulin Adjusted for BSA Measurement	Direct Glomerular Filtration Rate from Beta-Trace Protein Adjusted for Standard BSA Measurement	

2025-03-28	CDISC-6662	Update	C105443	CDISC Definition	LBTESTCD	Laboratory Test Code	Update CDISC Definition	A biomarker test that measures liver pathology through the assessment of a six-parameter blood test (for Alpha-2-macroglobulin, Haptoglobin, Apolipoprotein A1, Gamma-glutamyl transpeptidase (GGT), Total bilirubin, and Alanine aminotransferase (ALT)), taking into account the age and gender of the patient.	A biomarker test that measures liver pathology through the assessment of a six-parameter blood test (for Alpha-2-macroglobulin, Haptoglobin, Apolipoprotein A1, Gamma-glutamyl transpeptidase (GGT), Total bilirubin, and Alanine aminotransferase (ALT)), taking into account the age and sex of the patient.	

2025-03-28	CDISC-6662	Update	C110935	CDISC Definition	LBTESTCD	Laboratory Test Code	Update CDISC Definition	A kidney function test that estimates the fluid volume that is filtered from the kidney glomeruli to the Bowman's capsule per unit of time.	A kidney function test that estimates the fluid volume that is filtered from the kidney glomeruli to the Bowman's capsule per unit of time, which may or may not be indexed for body surface area.	

2025-03-28	CDISC-6662	Update	C122157	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	T Cells	

2025-03-28	CDISC-6662	Update	C127614	CDISC Definition	LBTESTCD	Laboratory Test Code	Update CDISC Definition	An estimation of the glomerular filtration rate adjusted for body surface area based on cystatin C and creatinine.	An estimation of the glomerular filtration rate adjusted for standard body surface area (1.73m2) based on cystatin C and creatinine.	

2025-03-28	N/A	Update	C127614	NCI Preferred Term	LBTESTCD	Laboratory Test Code	Update NCI Preferred Term	Glomerular Filtration Rate from Cystatin C and Creatinine Adjusted for BSA	Estimated Glomeluar Filtration Rate from Cystatin C and Creatinine Adjusted for Standard BSA	

2025-03-28	CDISC-6662	Update	C128975	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	Plasma Cells/Leuk	

2025-03-28	CDISC-6662	Update	C147351	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	Gran/Leuk	

2025-03-28	CDISC-6662	Update	C147385	CDISC Definition	LBTESTCD	Laboratory Test Code	Update CDISC Definition	A scoring system that evaluates liver pathology through the assessment of multiple blood test parameters, taking into account additional demographic factors such as the age and/or gender of the subject.	A scoring system that evaluates liver pathology through the assessment of multiple blood test parameters, taking into account additional demographic factors such as the age and/or sex of the subject.	

2025-03-28	N/A	Update	C147404	NCI Preferred Term	LBTESTCD	Laboratory Test Code	Update NCI Preferred Term	N-methylhistamine Measurement	N-Methylhistamine Measurement	

2025-03-28	CDISC-6662	Update	C163442	CDISC Definition	LBTESTCD	Laboratory Test Code	Update CDISC Definition	An estimation of the glomerular filtration rate adjusted for body surface area based on creatinine and urea nitrogen.	An estimation of the glomerular filtration rate adjusted for standard body surface area (1.73m2) based on creatinine and urea nitrogen.	

2025-03-28	N/A	Update	C163442	NCI Preferred Term	LBTESTCD	Laboratory Test Code	Update NCI Preferred Term	Glomerular Filtration Rate from Creatinine and Urea Nitrogen Adjusted for Body Surface Area Measurement	Estimated Glomerular Filtration Rate from Creatinine and Urea Nitrogen Adjusted for Standard BSA	

2025-03-28	CDISC-6662	Update	C163443	CDISC Definition	LBTESTCD	Laboratory Test Code	Update CDISC Definition	An estimation of the glomerular filtration rate adjusted for body surface area based on creatinine, urea nitrogen, and albumin.	An estimation of the glomerular filtration rate adjusted for standard body surface area (1.73m2) based on creatinine, urea nitrogen, and albumin.	

2025-03-28	N/A	Update	C163443	NCI Preferred Term	LBTESTCD	Laboratory Test Code	Update NCI Preferred Term	Glomerular Filtration Rate from Creatinine, Urea Nitrogen, and Albumin Adjusted for Body Surface Area Measurement	Estimated Glomerular Filtration Rate from Creatinine, Urea Nitrogen, and Albumin Adjusted for Standard BSA	

2025-03-28	CDISC-6462	Update	C165985	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	Protransforming Growth Factor Alpha	

2025-03-28	CDISC-6462	Update	C165985	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	TGF-Alpha	

2025-03-28	CDISC-6662	Update	C174314	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	B Cells	

2025-03-28	CDISC-6662	Update	C187987	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	Plasma Cells/Total Cells	

2025-03-28	CDISC-6462	Update	C198285	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	C-Type Lectin Domain Family 8 Member A	

2025-03-28	CDISC-6462	Update	C198285	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	CLEC8A	

2025-03-28	CDISC-6462	Update	C198285	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	Oxidized LDL Receptor 1	

2025-03-28	CDISC-6462	Update	C198285	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	Oxidized Low-Density Lipoprotein Receptor 1	

2025-03-28	CDISC-6662	Update	C199902	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	NF-H	

2025-03-28	CDISC-6662	Update	C199902	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	Neurofilament Heavy Polypeptide	

2025-03-28	CDISC-6662	Update	C199902	CDISC Synonym	LBTESTCD	Laboratory Test Code	Remove CDISC Synonym	Neurofilament Heavy Polypeptide: NF-H	- - -	

2025-03-28	CDISC-6662	Update	C209578	CDISC Synonym	LBTESTCD	Laboratory Test Code	Remove CDISC Synonym	Amyloid Probably Score	- - -	

2025-03-28	CDISC-6662	Update	C64481	CDISC Definition	LBTESTCD	Laboratory Test Code	Update CDISC Definition	A measurement of the conjugated or water-soluble bilirubin in a biological specimen.	A measurement of the glucuronidated bilirubin and albumin-bound bilirubin in a biological specimen.	

2025-03-28	CDISC-6662	Update	C64481	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	Conjugated Bilirubin + Albumin-Bound Bilirubin	

2025-03-28	CDISC-6662	Update	C64481	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	Conjugated Bilirubin + Delta Bilirubin	

2025-03-28	CDISC-6662	Update	C64483	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	Non-Glucuronidated Bilirubin	

2025-03-28	CDISC-6662	Update	C64483	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	Unconjugated Bilirubin	

2025-03-28	N/A	Update	C64849	NCI Preferred Term	LBTESTCD	Laboratory Test Code	Update NCI Preferred Term	Glycosylated Hemoglobin Measurement	Hemoglobin A1C Measurement	

2025-03-28	CDISC-6662	Update	C64849	CDISC Synonym	LBTESTCD	Laboratory Test Code	Remove CDISC Synonym	Glycated Hemoglobin	- - -	

2025-03-28	CDISC-6662	Update	C64849	CDISC Synonym	LBTESTCD	Laboratory Test Code	Remove CDISC Synonym	Glycosylated Hemoglobin A1C	- - -	

2025-03-28	N/A	Update	C81993	NCI Preferred Term	LBTESTCD	Laboratory Test Code	Update NCI Preferred Term	Tissue Plasminogen Activator Antigen Measurement	Tissue Plasminogen Activator Measurement	

2025-03-28	CDISC-6662	Update	C98735	CDISC Definition	LBTESTCD	Laboratory Test Code	Update CDISC Definition	An estimation of the glomerular filtration rate adjusted for body surface area based on creatinine.	An estimation of the glomerular filtration rate adjusted for standard body surface area (1.73m2) based on creatinine.	

2025-03-28	N/A	Update	C98735	NCI Preferred Term	LBTESTCD	Laboratory Test Code	Update NCI Preferred Term	Glomerular Filtration Rate from Creatinine Adjusted for BSA	Estimated Glomerular Filtration Rate from Creatinine Adjusted for Standard BSA	

2025-03-28	CDISC-6662	Update	C98736	CDISC Definition	LBTESTCD	Laboratory Test Code	Update CDISC Definition	An estimation of the glomerular filtration rate adjusted for body surface area based on cystatin C.	An estimation of the glomerular filtration rate adjusted for standard body surface area (1.73m2) based on cystatin C.	

2025-03-28	N/A	Update	C98736	NCI Preferred Term	LBTESTCD	Laboratory Test Code	Update NCI Preferred Term	Glomerular Filtration Rate from Cystatin C Adjusted for BSA	Estimated Glomerular Filtration Rate from Cystatin C Adjusted for Standard BSA	

2025-03-28	N/A	Update	C116164	NCI Preferred Term	LOC	Anatomical Location	Update NCI Preferred Term	Skin Of The Axilla	Skin of the Axilla	

2025-03-28	N/A	Update	C12360	NCI Preferred Term	LOC	Anatomical Location	Update NCI Preferred Term	Intra-Abdominal Lymph Node	Abdominal Lymph Node	

2025-03-28	N/A	Update	C41449	NCI Preferred Term	LOC	Anatomical Location	Update NCI Preferred Term	Epidural Spinal Canal Space	Epidural Spinal Space	

2025-03-28	N/A	Update	C3775	NCI Preferred Term	NEOPLASM	Neoplasm Type	Update NCI Preferred Term	Adnexal Carcinoma	Skin Adnexal Carcinoma	

2025-03-28	N/A	Update	C7580	NCI Preferred Term	NEOPLASM	Neoplasm Type	Update NCI Preferred Term	Skin Appendage Adenoma	Skin Adnexal Adenoma	

2025-03-28	CDISC-6662	Update	C166082	CDISC Definition	PKUNIT	PK Units of Measure	Update CDISC Definition	Nanogram equivalents of a radiolabeled substance per gram of matrix or tissue.	Nanogram equivalents of a substance per gram of matrix or tissue (e.g., radiolabeled dose).	

2025-03-28	CDISC-6662	Update	C166083	CDISC Definition	PKUNIT	PK Units of Measure	Update CDISC Definition	Nanogram equivalents of a radiolabeled substance per milliliter, divided by milligram equivalents (radiolabeled dose).	Nanogram equivalents of a substance per milliliter, divided by milligram equivalents (e.g., radiolabeled dose).	

2025-03-28	CDISC-6662	Update	C166084	CDISC Definition	PKUNIT	PK Units of Measure	Update CDISC Definition	Picogram equivalents of a radiolabeled substance per gram of matrix or tissue.	Picogram equivalents of a substance per gram of matrix or tissue (e.g., radiolabeled dose).	

2025-03-28	CDISC-6662	Update	C166085	CDISC Definition	PKUNIT	PK Units of Measure	Update CDISC Definition	Picogram equivalents of a radiolabeled substance per milliliter of matrix or fluid.	Picogram equivalents of a substance per milliliter of matrix or fluid (e.g., radiolabeled dose).	

2025-03-28	CDISC-6662	Update	C166086	CDISC Definition	PKUNIT	PK Units of Measure	Update CDISC Definition	Picogram equivalents of a radiolabeled substance per milliliter, divided by milligram equivalents (radiolabeled dose).	Picogram equivalents of a substance per milliliter, divided by milligram equivalents (e.g., radiolabeled dose).	

2025-03-28	CDISC-6662	Update	C166087	CDISC Definition	PKUNIT	PK Units of Measure	Update CDISC Definition	Microgram equivalents of a radiolabeled substance per gram of matrix or tissue.	Microgram equivalents of a substance per gram of matrix or tissue (e.g., radiolabeled dose).	

2025-03-28	CDISC-6662	Update	C166088	CDISC Definition	PKUNIT	PK Units of Measure	Update CDISC Definition	Microgram equivalents of a radiolabeled substance per milliliter, divided by milligram equivalents (radiolabeled dose).	Microgram equivalents of a substance per milliliter, divided by milligram equivalents (e.g., radiolabeled dose).	

2025-03-28	CDISC-6662	Update	C38246	CDISC Definition	ROUTE	Route of Administration Response	Update CDISC Definition	Administration within the stomach. (FDA)	Administration directly into the stomach, usually by means of a tube.	

2025-03-28	CDISC-6662	Update	C78374	CDISC Definition	ROUTE	Route of Administration Response	Update CDISC Definition	Administration through the mouth and into the stomach, usually by means of a tube. (NCI)	For nonclinical studies, administration through the mouth and into the stomach, usually by means of an oral gavage tube.	

2025-03-28	N/A	Update	C68768	NCI Preferred Term	SPECCOND	Specimen Condition	Update NCI Preferred Term	Contamination	Contaminated	

2025-03-28	CDISC-6662	Update	C210095	CDISC Submission Value	STSPRM	SEND Trial Summary Parameter Test Name	Update CDISC Submission Value	In vitro Phenotypic Expression Duration Unit	In vitro Phenotypic Expression Dur Unit	

2025-03-28	CDISC-6662	Update	C210095	CDISC Synonym	STSPRM	SEND Trial Summary Parameter Test Name	Add new CDISC Synonym	- - -	In vitro Phenotypic Expression Dur Unit	

2025-03-28	CDISC-6662	Update	C210095	CDISC Synonym	STSPRMCD	SEND Trial Summary Parameter Test Code	Add new CDISC Synonym	- - -	In vitro Phenotypic Expression Dur Unit	

2025-03-28	CDISC-6662	Update	C166082	CDISC Definition	UNIT	Unit	Update CDISC Definition	Nanogram equivalents of a radiolabeled substance per gram of matrix or tissue.	Nanogram equivalents of a substance per gram of matrix or tissue (e.g., radiolabeled dose).