Release Date	Request Code	Change Type	NCI Code	CDISC Term Type	CDISC Codelist (Short Name)	CDISC Codelist (Long Name)	Change Summary	Original	New	Change Implementation Instructions
2018-09-28	CDISC-3566	Update	C90425	CDISC Definition	DSDECOD	Standardized Disposition Term	Update CDISC Definition	An indication that a subject was euthanized due to ethical reasons, such as being near death.	An indication that a subject was euthanized due to ethical reasons, such as being in poor health or near death.	
2018-09-28	CDISC-3394	Add	C154717	Term	EGMETHOD	ECG Test Method	Add new term to existing codelist	- - -	CONTINUOUS SURFACE ECG RECORDING FOR NON-HUMAN SPECIES	
2018-09-28	CDISC-3395	Add	C154718	Term	EGMETHOD	ECG Test Method	Add new term to existing codelist	- - -	CONTINUOUS ECG RECORDING FOR NON-HUMAN SPECIES USING IMPLANTED LEADS	
2018-09-28	CDISC-3412	Add	C28012	Term	LAT	Laterality	Add new term to existing codelist	- - -	UNILATERAL	"C68598 is removed from codelist and being replaced with C28012, which is being added to the codelist. The NCI concept did not match the granularity of the CDISC concept.
"
2018-09-28	CDISC-3412	Remove	C68598	Term	LAT	Laterality	Remove term entirely from codelist	UNILATERAL	- - -	"C68598 is removed from codelist and being replaced with C28012, which is being added to the codelist. The NCI concept did not match the granularity of the CDISC concept.
"
2018-09-28	CDISC-3566	Update	C119270	CDISC Definition	LBTEST	Laboratory Test Name	Update CDISC Definition	A measurement of the amount of acid required to return a biological specimen to a normal pH under standard conditions.	A calculated measurement of the amount of acid required to return blood to a normal pH under standard conditions.	
2018-09-28	CDISC-3566	Update	C119270	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	Actual Base Excess	
2018-09-28	CDISC-3165	Update	C119272	CDISC Definition	LBTEST	Laboratory Test Name	Update CDISC Definition	A measurement of calcium, which has been corrected for albumin, in a biological specimen.	A measurement of calcium, which has been corrected using an unspecified protein, in a biological specimen.	
2018-09-28	CDISC-3232	Update	C147359	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	FO2 Hb	
2018-09-28	CDISC-3232	Update	C147359	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	Fractioned Oxyhemoglobin	
2018-09-28	CDISC-3233	Update	C147367	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	FMET HB	
2018-09-28	CDISC-3233	Update	C147367	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	Fractionated Methemoglobin	
2018-09-28	CDISC-3106	Add	C154719	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Erythroid Cells/Total Cells	
2018-09-28	CDISC-3106	Add	C154720	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Erythroid Cells/Nucleated Cells	
2018-09-28	CDISC-3169	Add	C154721	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Standard Base Excess	
2018-09-28	CDISC-3183	Add	C154722	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Megakaryocytes/Leukocytes	
2018-09-28	CDISC-3220	Add	C154723	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Immature Platelets	
2018-09-28	CDISC-3230	Add	C154724	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Krebs von den Lungen-6	
2018-09-28	CDISC-3231	Add	C154725	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Islet Cell Antibody	
2018-09-28	CDISC-3234	Add	C154726	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Atherogenic Index of Plasma	
2018-09-28	CDISC-3252; CDISC-3253	Add	C154727	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Fibroblast Growth Factor 19	
2018-09-28	CDISC-3255	Add	C154728	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Soluble CD163	
2018-09-28	CDISC-3256; CDISC-3290	Add	C154729	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Retinol Binding Protein/Creatinine	
2018-09-28	CDISC-3260	Add	C154730	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	S100 Calcium Binding Protein A8	
2018-09-28	CDISC-3260	Add	C154731	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	4-Hydroxymidazolam	
2018-09-28	CDISC-3260	Add	C154732	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	1-Hydroxymidazolam	
2018-09-28	CDISC-3260	Add	C154733	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Bizarre Platelets	
2018-09-28	CDISC-3260	Add	C154734	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Albumin Index	
2018-09-28	CDISC-3260	Add	C154735	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	CSF IgG Index	
2018-09-28	CDISC-3260	Add	C154736	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	E-selectin	
2018-09-28	CDISC-3260	Add	C154737	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Immunoglobulin Heavy Constant Gamma 2	
2018-09-28	CDISC-3260	Add	C154738	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Immunoglobulin Heavy Constant Gamma 4	
2018-09-28	CDISC-3274; CDISC-3290	Add	C154739	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Tryptophan	
2018-09-28	CDISC-3274	Add	C154740	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Kynurenine	
2018-09-28	CDISC-3274	Add	C154741	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Lactulose	
2018-09-28	CDISC-3274	Add	C154742	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Mannitol	
2018-09-28	CDISC-3286	Add	C154743	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Aldrin Epoxidase	
2018-09-28	CDISC-3288; CDISC-3289	Add	C154744	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Nociceptin	
2018-09-28	CDISC-3290	Add	C154745	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Thiocyanate	
2018-09-28	CDISC-3290	Add	C154746	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	HLA Class IA Antigen	
2018-09-28	CDISC-3290	Add	C154747	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	HLA Class IB Antigen	
2018-09-28	CDISC-3290	Add	C154748	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	HLA Class IC Antigen	
2018-09-28	CDISC-3290	Add	C154749	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	HLA DR Beta1 Antigen	
2018-09-28	CDISC-3290	Add	C154750	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	HLA DQ Beta1 Antigen	
2018-09-28	CDISC-3290	Add	C154751	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	HLA DP Beta1 Antigen	
2018-09-28	CDISC-3290	Add	C154752	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Factor VIII Inhibitor	
2018-09-28	CDISC-3566	Add	C154753	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Calcium, Albumin Corrected	
2018-09-28	CDISC-3566	Add	C154755	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Neutrophils, Segmented + Band Form	
2018-09-28	CDISC-3566	Add	C154756	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Neutrophils, Seg + Band Form + Precursor	
2018-09-28	CDISC-3260	Add	C154757	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Mononuclear Cells	
2018-09-28	CDISC-3290	Add	C154758	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Homocitrulline	
2018-09-28	CDISC-3290	Add	C154759	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Alpha-Aminobutyric Acid	
2018-09-28	CDISC-3290	Add	C154760	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Sarcosine	
2018-09-28	CDISC-3290	Add	C154761	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Alpha-Aminoadipic Acid	
2018-09-28	CDISC-3290	Add	C154762	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Alloisoleucine	
2018-09-28	CDISC-3290	Add	C154763	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Argininosuccinic Acid	
2018-09-28	CDISC-3290	Add	C154764	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Beta Alanine	
2018-09-28	CDISC-3290	Add	C154765	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Beta-Aminobutyric Acid	
2018-09-28	CDISC-3290	Add	C154766	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Gamma-Aminobutyric Acid	
2018-09-28	CDISC-3290	Add	C154767	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Hydroxylysine	
2018-09-28	CDISC-3290	Add	C154768	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Glucagon-Like Peptide-1, Inactive Form	
2018-09-28	CDISC-3290	Add	C154769	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Anti-Double Stranded DNA IgG	
2018-09-28	C63321	Update	C63321	CDISC Synonym	LBTEST	Laboratory Test Name	Remove CDISC Synonym	ANC	- - -	ANC' and 'Total ANC' are used inconsistently to mean multiple things and are not a precisely or consistently defined concept across the industry. Please see the new terms (P35) C154755 (NEUTSGB/Neutrophils, Segmented + Band Form) and C154756 (NEUTSGBP/Neutrophils, Seg + Band Form + Precursor) if more precision is required.
2018-09-28	CDISC-3352	Update	C64810	CDISC Definition	LBTEST	Laboratory Test Name	Update CDISC Definition	A measurement of the nitrite in a urine specimen.	A measurement of the nitrite in a biological specimen.	
2018-09-28	CDISC-3279	Add	C74949	Term	LBTEST	Laboratory Test Name	Add new term to existing codelist	- - -	Lipid	
2018-09-28	CDISC-3117	Update	C81974	CDISC Synonym	LBTEST	Laboratory Test Name	Add new CDISC Synonym	- - -	Antiglobulin Test Polyspecific, Direct	
2018-09-28	CDISC-3566	Update	C119270	CDISC Definition	LBTESTCD	Laboratory Test Code	Update CDISC Definition	A measurement of the amount of acid required to return a biological specimen to a normal pH under standard conditions.	A calculated measurement of the amount of acid required to return blood to a normal pH under standard conditions.	
2018-09-28	CDISC-3566	Update	C119270	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	Actual Base Excess	
2018-09-28	CDISC-3165	Update	C119272	CDISC Definition	LBTESTCD	Laboratory Test Code	Update CDISC Definition	A measurement of calcium, which has been corrected for albumin, in a biological specimen.	A measurement of calcium, which has been corrected using an unspecified protein, in a biological specimen.	
2018-09-28	CDISC-3232	Update	C147359	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	FO2 Hb	
2018-09-28	CDISC-3232	Update	C147359	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	Fractioned Oxyhemoglobin	
2018-09-28	CDISC-3233	Update	C147367	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	FMET HB	
2018-09-28	CDISC-3233	Update	C147367	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	Fractionated Methemoglobin	
2018-09-28	CDISC-3106	Add	C154719	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	ERCECE	
2018-09-28	CDISC-3106	Add	C154720	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	ERCENC	
2018-09-28	CDISC-3169	Add	C154721	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	STBSEXCS	
2018-09-28	CDISC-3183	Add	C154722	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	KRCYMGLE	
2018-09-28	CDISC-3220	Add	C154723	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	PLATIM	
2018-09-28	CDISC-3230	Add	C154724	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	KL6	
2018-09-28	CDISC-3231	Add	C154725	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	ICAB	
2018-09-28	CDISC-3234	Add	C154726	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	ATHPIDX	
2018-09-28	CDISC-3252; CDISC-3253	Add	C154727	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	FGF19	
2018-09-28	CDISC-3255	Add	C154728	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	CD163S	
2018-09-28	CDISC-3256; CDISC-3290	Add	C154729	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	RBPCREAT	
2018-09-28	CDISC-3260	Add	C154730	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	S100A8	
2018-09-28	CDISC-3260	Add	C154731	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	HYDMDZ4	
2018-09-28	CDISC-3260	Add	C154732	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	HYDMDZ1	
2018-09-28	CDISC-3260	Add	C154733	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	PLATBIZ	
2018-09-28	CDISC-3260	Add	C154734	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	ALBIDX	
2018-09-28	CDISC-3260	Add	C154735	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	CSFIGIDX	
2018-09-28	CDISC-3260	Add	C154736	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	ESELECT	
2018-09-28	CDISC-3260	Add	C154737	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	IGHG2	
2018-09-28	CDISC-3260	Add	C154738	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	IGHG4	
2018-09-28	CDISC-3274; CDISC-3290	Add	C154739	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	TRP	
2018-09-28	CDISC-3274	Add	C154740	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	KYNURNN	
2018-09-28	CDISC-3274	Add	C154741	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	LACTULOS	
2018-09-28	CDISC-3274	Add	C154742	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	MANNITOL	
2018-09-28	CDISC-3286	Add	C154743	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	ALDEPX	
2018-09-28	CDISC-3288; CDISC-3289	Add	C154744	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	NCCPTN	
2018-09-28	CDISC-3290	Add	C154745	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	SCN	
2018-09-28	CDISC-3290	Add	C154746	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	HLAA	
2018-09-28	CDISC-3290	Add	C154747	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	HLAB	
2018-09-28	CDISC-3290	Add	C154748	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	HLAC	
2018-09-28	CDISC-3290	Add	C154749	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	HLADRB1	
2018-09-28	CDISC-3290	Add	C154750	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	HLADQB1	
2018-09-28	CDISC-3290	Add	C154751	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	HLADPB1	
2018-09-28	CDISC-3290	Add	C154752	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	FCT8INH	
2018-09-28	CDISC-3566	Add	C154753	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	CACRALB	
2018-09-28	CDISC-3566	Add	C154755	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	NEUTSGB	
2018-09-28	CDISC-3566	Add	C154756	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	NEUTSGBP	
2018-09-28	CDISC-3260	Add	C154757	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	MNC	
2018-09-28	CDISC-3290	Add	C154758	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	HOMOCIT	
2018-09-28	CDISC-3290	Add	C154759	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	AAMBTAC	
2018-09-28	CDISC-3290	Add	C154760	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	SARCOSIN	
2018-09-28	CDISC-3290	Add	C154761	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	AAMAPAC	
2018-09-28	CDISC-3290	Add	C154762	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	ALLOILE	
2018-09-28	CDISC-3290	Add	C154763	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	ARGSAC	
2018-09-28	CDISC-3290	Add	C154764	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	BALA	
2018-09-28	CDISC-3290	Add	C154765	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	BAMBTAC	
2018-09-28	CDISC-3290	Add	C154766	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	GAMBTAC	
2018-09-28	CDISC-3290	Add	C154767	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	HYXLYS	
2018-09-28	CDISC-3290	Add	C154768	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	GLP1IAC	
2018-09-28	CDISC-3290	Add	C154769	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	DDNAIGAB	
2018-09-28	C63321	Update	C63321	CDISC Synonym	LBTESTCD	Laboratory Test Code	Remove CDISC Synonym	ANC	- - -	ANC' and 'Total ANC' are used inconsistently to mean multiple things and are not a precisely or consistently defined concept across the industry. Please see the new terms (P35) C154755 (NEUTSGB/Neutrophils, Segmented + Band Form) and C154756 (NEUTSGBP/Neutrophils, Seg + Band Form + Precursor) if more precision is required.
2018-09-28	CDISC-3352	Update	C64810	CDISC Definition	LBTESTCD	Laboratory Test Code	Update CDISC Definition	A measurement of the nitrite in a urine specimen.	A measurement of the nitrite in a biological specimen.	
2018-09-28	CDISC-3279	Add	C74949	Term	LBTESTCD	Laboratory Test Code	Add new term to existing codelist	- - -	LIPID	
2018-09-28	CDISC-3117	Update	C81974	CDISC Synonym	LBTESTCD	Laboratory Test Code	Add new CDISC Synonym	- - -	Antiglobulin Test Polyspecific, Direct	
2018-09-28	CDISC-3181	Add	C106042	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	DISTANT LYMPH NODE	
2018-09-28	CDISC-3180	Update	C12220	CDISC Synonym	LOC	Anatomical Location	Add new CDISC Synonym	- - -	Vermillion of the Lip	
2018-09-28	CDISC-3566	Add	C12266	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	COLON, HEPATIC FLEXURE	
2018-09-28	CDISC-3248	Add	C12267	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	COLON, SPLENIC FLEXURE	
2018-09-28	CDISC-3248	Add	C12315	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	FUNDUS UTERI	
2018-09-28	CDISC-3248	Add	C12316	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	CORPUS UTERI	
2018-09-28	CDISC-3248	Add	C12734	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	ILIAC VEIN	
2018-09-28	CDISC-3248	Add	C12877	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	VENOUS SINUS	
2018-09-28	CDISC-3248	Add	C12883	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	BRACHIAL VEIN	
2018-09-28	CDISC-3246	Add	C13272	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	PLACENTA	
2018-09-28	CDISC-3248	Add	C154703	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	CALF MUSCULAR VEIN	
2018-09-28	CDISC-3248	Add	C154770	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	BUCCAL LYMPH NODE	
2018-09-28	CDISC-3248	Add	C154771	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	COMMON FEMORAL VEIN	
2018-09-28	CDISC-3248	Add	C154772	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	FIBULAR VEIN	
2018-09-28	CDISC-3248	Add	C154773	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	GASTRIC CURVATURE LYMPH NODE	
2018-09-28	CDISC-3248	Add	C154774	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	PERIRECTAL LYMPH NODE	
2018-09-28	CDISC-3248	Add	C154775	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	PRESACRAL LYMPH NODE	
2018-09-28	CDISC-3248	Add	C154776	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	PROFUNDA FEMORIS VEIN	
2018-09-28	CDISC-3260	Add	C154777	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	SENSORIMOTOR CORTEX	
2018-09-28	CDISC-3260	Add	C154778	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	POSTERIOR CINGULATE CORTEX	
2018-09-28	CDISC-3260	Add	C154779	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	PREFRONTAL CORTEX	
2018-09-28	CDISC-3274	Add	C154780	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	SHIN	
2018-09-28	CDISC-3370	Add	C154781	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	L5-S1 INTERVERTEBRAL SPACE	
2018-09-28	CDISC-3248	Add	C32115	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	ANTERIOR TIBIAL VEIN	
2018-09-28	CDISC-3248	Update	C32250	CDISC Synonym	LOC	Anatomical Location	Add new CDISC Synonym	- - -	Calcaneum	
2018-09-28	CDISC-3248	Update	C32250	CDISC Synonym	LOC	Anatomical Location	Add new CDISC Synonym	- - -	Calcaneus Bone	
2018-09-28	CDISC-3248	Add	C32814	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	BRACHIOCEPHALIC ARTERY	
2018-09-28	CDISC-3248	Add	C32818	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	INTERATRIAL SEPTUM	
2018-09-28	CDISC-3248	Add	C33004	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	GREAT SAPHENOUS VEIN	
2018-09-28	CDISC-3248	Add	C33339	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	POPLITEAL VEIN	
2018-09-28	CDISC-3248	Add	C33386	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	POSTERIOR TIBIAL VEIN	
2018-09-28	CDISC-3566	Add	C52886	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	ORBICULARIS OCULI MUSCLE	
2018-09-28	CDISC-3248	Add	C53037	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	CEREBRAL VEIN	
2018-09-28	CDISC-3248	Add	C53055	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	MESENTERIC VEIN	
2018-09-28	CDISC-3248	Add	C60801	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	DISTAL COMMON BILE DUCT	
2018-09-28	CDISC-3248	Add	C96803	Term	LOC	Anatomical Location	Add new term to existing codelist	- - -	INTRAHEPATIC LARGE BILE DUCT	
2018-09-28	CDISC-1796	Add	C154892	Term	NEOPLASM	Neoplasm Type	Add new term to existing codelist	- - -	ADENOCARCINOMA ARISING IN FIBROADENOMA, MALIGNANT	
2018-09-28	CDISC-3566	Remove	C4047	Term	NEOPLASM	Neoplasm Type	Remove term entirely from codelist	ASTROCYTOMA, PILOCYTIC, BENIGN	- - -	C4047 is removed from codelist and being replaced with C119574, which is already published in the codelist. This tumor is never considered benign. Please use C119574 or request another specific tumor type.
2018-09-28	CDISC-3566	Remove	C4049	Term	NEOPLASM	Neoplasm Type	Remove term entirely from codelist	EPENDYMOMA, ANAPLASTIC, MALIGNANT	- - -	C4049 is removed from codelist and being replaced with C119575, which is already published in the codelist. Please use C119575 or request another specific tumor type.
2018-09-28	CDISC-3566	Remove	C4051	Term	NEOPLASM	Neoplasm Type	Remove term entirely from codelist	MENINGIOMA, ANAPLASTIC, MALIGNANT	- - -	C4051 is removed from codelist and being replaced with C38938, which is already published in the codelist. Please use C38938 or request another specific tumor type.
2018-09-28	CDISC-3566	Remove	C4326	Term	NEOPLASM	Neoplasm Type	Remove term entirely from codelist	OLIGODENDROGLIOMA, ANAPLASTIC, MALIGNANT	- - -	C4326 is removed from codelist and being replaced with C119577, which is already published in the codelist. Please use C119577 or request another specific tumor type.
2018-09-28	CDISC-3566	Remove	C9477	Term	NEOPLASM	Neoplasm Type	Remove term entirely from codelist	ASTROCYTOMA, ANAPLASTIC, MALIGNANT	- - -	C9477 is removed from codelist and being replaced with C119574, which is already published in the codelist. Please use C119574 or request another specific tumor type.
2018-09-28	CDISC-2749	Add	C154893	Term	NONNEO	Non-Neoplastic Finding Type	Add new term to existing codelist	- - -	GROWTH PLATE OPEN	
2018-09-28	CDISC-2754	Add	C154894	Term	NONNEO	Non-Neoplastic Finding Type	Add new term to existing codelist	- - -	SQUAMOUS PLAQUE/CYST	
2018-09-28	CDISC-3413	Add	C154895	Term	NONNEO	Non-Neoplastic Finding Type	Add new term to existing codelist	- - -	CYTOPLASMIC ALTERATION	
2018-09-28	CDISC-2755	Add	C16900	Term	NONNEO	Non-Neoplastic Finding Type	Add new term to existing codelist	- - -	NEOVASCULARIZATION	
2018-09-28	CDISC-2748	Add	C34652	Term	NONNEO	Non-Neoplastic Finding Type	Add new term to existing codelist	- - -	GRANULATION TISSUE	
2018-09-28	CDISC-2747	Add	C35584	Term	NONNEO	Non-Neoplastic Finding Type	Add new term to existing codelist	- - -	ERYTHROPHAGOCYTOSIS	
2018-09-28	CDISC-3251	Add	C154838	Term	PKPARM	PK Parameters	Add new term to existing codelist	- - -	Absolute Bioavailability	
2018-09-28	CDISC-3251	Add	C154839	Term	PKPARM	PK Parameters	Add new term to existing codelist	- - -	Relative Bioavailability	
2018-09-28	CDISC-3251	Add	C154840	Term	PKPARM	PK Parameters	Add new term to existing codelist	- - -	Fraction Bound	
2018-09-28	CDISC-3265	Add	C154841	Term	PKPARM	PK Parameters	Add new term to existing codelist	- - -	Total CL Pred for Unbound Drug	
2018-09-28	CDISC-3265	Add	C154842	Term	PKPARM	PK Parameters	Add new term to existing codelist	- - -	Total CL Obs for Unbound Drug	
2018-09-28	CDISC-3265	Add	C154843	Term	PKPARM	PK Parameters	Add new term to existing codelist	- - -	Renal CL for Unbound Drug	
2018-09-28	CDISC-3265	Add	C154844	Term	PKPARM	PK Parameters	Add new term to existing codelist	- - -	Apparent CL for Unbound Drug	
2018-09-28	CDISC-3251	Add	C154845	Term	PKPARM	PK Parameters	Add new term to existing codelist	- - -	AUC Infinity Obs, Unbound Drug	
2018-09-28	CDISC-3251	Add	C154846	Term	PKPARM	PK Parameters	Add new term to existing codelist	- - -	AUC Infinity Pred, Unbound Drug	
2018-09-28	CDISC-3265	Add	C154847	Term	PKPARM	PK Parameters	Add new term to existing codelist	- - -	AUC to Last Nonzero Conc, Unbound Drug	
2018-09-28	CDISC-3251	Add	C154848	Term	PKPARM	PK Parameters	Add new term to existing codelist	- - -	Max Conc, Unbound Drug	
2018-09-28	CDISC-3251	Add	C154849	Term	PKPARM	PK Parameters	Add new term to existing codelist	- - -	Renal CL as Pct CL EV	
2018-09-28	CDISC-3251	Add	C154850	Term	PKPARM	PK Parameters	Add new term to existing codelist	- - -	Renal CL as Pct CL IV	
2018-09-28	CDISC-3251	Add	C154838	Term	PKPARMCD	PK Parameters Code	Add new term to existing codelist	- - -	FABS	
2018-09-28	CDISC-3251	Add	C154839	Term	PKPARMCD	PK Parameters Code	Add new term to existing codelist	- - -	FREL	
2018-09-28	CDISC-3251	Add	C154840	Term	PKPARMCD	PK Parameters Code	Add new term to existing codelist	- - -	FB	
2018-09-28	CDISC-3265	Add	C154841	Term	PKPARMCD	PK Parameters Code	Add new term to existing codelist	- - -	CLPUB	
2018-09-28	CDISC-3265	Add	C154842	Term	PKPARMCD	PK Parameters Code	Add new term to existing codelist	- - -	CLOUB	
2018-09-28	CDISC-3265	Add	C154843	Term	PKPARMCD	PK Parameters Code	Add new term to existing codelist	- - -	RNCLUB	
2018-09-28	CDISC-3265	Add	C154844	Term	PKPARMCD	PK Parameters Code	Add new term to existing codelist	- - -	CLFUB	
2018-09-28	CDISC-3251	Add	C154845	Term	PKPARMCD	PK Parameters Code	Add new term to existing codelist	- - -	AUCIFOUB	
2018-09-28	CDISC-3251	Add	C154846	Term	PKPARMCD	PK Parameters Code	Add new term to existing codelist	- - -	AUCIFPUB	
2018-09-28	CDISC-3265	Add	C154847	Term	PKPARMCD	PK Parameters Code	Add new term to existing codelist	- - -	AUCLSTUB	
2018-09-28	CDISC-3251	Add	C154848	Term	PKPARMCD	PK Parameters Code	Add new term to existing codelist	- - -	CMAXUB	
2018-09-28	CDISC-3251	Add	C154849	Term	PKPARMCD	PK Parameters Code	Add new term to existing codelist	- - -	CLRPCLEV	
2018-09-28	CDISC-3251	Add	C154850	Term	PKPARMCD	PK Parameters Code	Add new term to existing codelist	- - -	CLRPCLIV	
2018-09-28	CDISC-3566	Add	C1514	Term	PPTMDARS	Planned Pharmacologic Target Mode of Action Response	Add new term to new codelist	- - -	RECEPTOR AGONIST	
2018-09-28	CDISC-3566	Add	C154684	CDISC Codelist	PPTMDARS	Planned Pharmacologic Target Mode of Action Response	Addition of new codelist	- - -	PPTMDARS	
2018-09-28	CDISC-3566	Add	C154897	Term	PPTMDARS	Planned Pharmacologic Target Mode of Action Response	Add new term to new codelist	- - -	ACTIVATOR	
2018-09-28	CDISC-3566	Add	C154898	Term	PPTMDARS	Planned Pharmacologic Target Mode of Action Response	Add new term to new codelist	- - -	INHIBITOR	
2018-09-28	CDISC-3566	Add	C154899	Term	PPTMDARS	Planned Pharmacologic Target Mode of Action Response	Add new term to new codelist	- - -	FULL RECEPTOR AGONIST	
2018-09-28	CDISC-3566	Add	C154900	Term	PPTMDARS	Planned Pharmacologic Target Mode of Action Response	Add new term to new codelist	- - -	PARTIAL RECEPTOR AGONIST	
2018-09-28	CDISC-3566	Add	C154901	Term	PPTMDARS	Planned Pharmacologic Target Mode of Action Response	Add new term to new codelist	- - -	INVERSE RECEPTOR AGONIST	
2018-09-28	CDISC-3566	Add	C154902	Term	PPTMDARS	Planned Pharmacologic Target Mode of Action Response	Add new term to new codelist	- - -	AGONIST-ANTAGONIST	
2018-09-28	CDISC-3566	Add	C154903	Term	PPTMDARS	Planned Pharmacologic Target Mode of Action Response	Add new term to new codelist	- - -	ALLOSTERIC POTENTIATOR	
2018-09-28	CDISC-3566	Add	C154904	Term	PPTMDARS	Planned Pharmacologic Target Mode of Action Response	Add new term to new codelist	- - -	ALLOSTERIC MODULATOR	
2018-09-28	CDISC-3566	Add	C94373	Term	PPTMDARS	Planned Pharmacologic Target Mode of Action Response	Add new term to new codelist	- - -	RECEPTOR ANTAGONIST	
2018-09-28	CDISC-3368	Update	C95087	CDISC Definition	SDOMAIN	SEND Domain Abbreviation	Update CDISC Definition	An events domain that contains the diagnosis of the cause of death for a subject.	A findings domain that contains the diagnosis of the cause of death for a subject.	
2018-09-28	CDISC-3180	Update	C12220	CDISC Synonym	SPEC	Specimen	Add new CDISC Synonym	- - -	Vermillion of the Lip	
2018-09-28	CDISC-3111	Remove	C12272	Term	SPEC	Specimen	Remove term entirely from codelist	DUCT, PANCREATIC	- - -	C12272 is removed from codelist and being replaced with C154699, which is being added to the codelist. The term was meant to convey any of the pancreatic ducts (Main+Accessory), not just the Main Pancreatic Duct, which is the intent of C12272.
2018-09-28	CDISC-3269; CDISC-3423	Add	C13010	Term	SPEC	Specimen	Add new term to existing codelist	- - -	GLAND, BRUNNER'S	
2018-09-28	CDISC-3111	Add	C154699	Term	SPEC	Specimen	Add new term to existing codelist	- - -	DUCT, PANCREATIC	C12272 is removed from codelist and being replaced with C154699, which is being added to the codelist. The term was meant to convey any of the pancreatic ducts (Main+Accessory), not just the Main Pancreatic Duct, which is the intent of C12272.
2018-09-28	CDISC-2883	Add	C154896	Term	STSPRM	SEND Trial Summary Parameter Test Name	Add new term to existing codelist	- - -	Test Article Physical Substance Class	
2018-09-28	CDISC-2883	Add	C154896	Term	STSPRMCD	SEND Trial Summary Parameter Test Code	Add new term to existing codelist	- - -	TAPHSCLS	
2018-09-28	CDISC-3140	Add	C154680	Term	UNIT	Unit	Add new term to existing codelist	- - -	NIU	RFU and NIU are no longer considered synonymous. A new term C154680/NIU is being split out from the existing concept C77535/RFU.
2018-09-28	CDISC-3106	Add	C154854	Term	UNIT	Unit	Add new term to existing codelist	- - -	Hz/s	
2018-09-28	CDISC-3260	Add	C154855	Term	UNIT	Unit	Add new term to existing codelist	- - -	mL/100g/min	
2018-09-28	CDISC-3357	Add	C154856	Term	UNIT	Unit	Add new term to existing codelist	- - -	Enzyme U/g Hb	
2018-09-28	CDISC-3357	Add	C154857	Term	UNIT	Unit	Add new term to existing codelist	- - -	P	
2018-09-28	CDISC-3357	Add	C154858	Term	UNIT	Unit	Add new term to existing codelist	- - -	um/s	
2018-09-28	CDISC-3400	Add	C154859	Term	UNIT	Unit	Add new term to existing codelist	- - -	uSiemens	
2018-09-28	n/a	Update	C42537	CDISC Definition	UNIT	Unit	Update CDISC Definition	A basic unit of thermodynamic temperature, one of the seven base units of the International System of Units (Systeme International d'Unites, SI). It is 1/273.16th of the thermodynamic temperature of the triple point of water, This sets the size of the kelvin unit for temperature differences and defines the thermodynamic temperature of an equilibrium mixture of waters ice-liquid-vapor as 273.16 K, where 0 K is the lowest possible temperature ("absolute zero").	A basic unit of thermodynamic temperature, one of the seven base units of the International System of Units (Systeme International d'Unites, SI). It is 1/273.16th of the thermodynamic temperature of the triple point of water. This sets the size of the kelvin unit for temperature differences and defines the thermodynamic temperature of an equilibrium mixture of waters ice-liquid-vapor as 273.16 K, where 0 K is the lowest possible temperature ("absolute zero").	
2018-09-28	CDISC-3357	Add	C69092	Term	UNIT	Unit	Add new term to existing codelist	- - -	cP	
2018-09-28	CDISC-3357	Add	C73681	Term	UNIT	Unit	Add new term to existing codelist	- - -	OD Unit	
2018-09-28	CDISC-3140	Update	C77535	CDISC Submission Value	UNIT	Unit	Update CDISC Submission Value	NIU	RFU	RFU and NIU are no longer considered synonymous. A new term C154680/NIU is being split out from the existing concept C77535/RFU.
2018-09-28	CDISC-3140	Update	C77535	CDISC Definition	UNIT	Unit	Update CDISC Definition	A unit of measurement that estimates the size or amount of material in a sample by normalizing its luminescence to that of a reference standard. (NCI)	An arbitrary unit used to measure the intensity of the emitted fluorescent light in a sample; it is dependent on instrument and measurement parameters.	RFU and NIU are no longer considered synonymous. A new term C154680/NIU is being split out from the existing concept C77535/RFU.
2018-09-28	CDISC-3140	Update	C77535	NCI Preferred Term	UNIT	Unit	Update NCI Preferred Term	Relative Fluorescence Unit	Relative Fluorescence Intensity Unit	RFU and NIU are no longer considered synonymous. A new term C154680/NIU is being split out from the existing concept C77535/RFU.
2018-09-28	CDISC-3140	Update	C77535	CDISC Synonym	UNIT	Unit	Add new CDISC Synonym	- - -	Relative Fluorescence Unit	RFU and NIU are no longer considered synonymous. A new term C154680/NIU is being split out from the existing concept C77535/RFU.
2018-09-28	CDISC-3140	Update	C77535	CDISC Synonym	UNIT	Unit	Remove CDISC Synonym	Normalized Fluorescence Intensity Unit	- - -	RFU and NIU are no longer considered synonymous. A new term C154680/NIU is being split out from the existing concept C77535/RFU.
2018-09-28	CDISC-3140	Update	C77535	CDISC Synonym	UNIT	Unit	Remove CDISC Synonym	Normalized Intensity Unit	- - -	RFU and NIU are no longer considered synonymous. A new term C154680/NIU is being split out from the existing concept C77535/RFU.
2018-09-28	CDISC-3140	Update	C77535	CDISC Synonym	UNIT	Unit	Remove CDISC Synonym	Relative Intensity Unit	- - -	RFU and NIU are no longer considered synonymous. A new term C154680/NIU is being split out from the existing concept C77535/RFU.
2018-09-28	CDISC-3357	Add	C85741	Term	UNIT	Unit	Add new term to existing codelist	- - -	ng/day	
2018-09-28	n/a	Update	C42537	CDISC Definition	VSRESU	Units for Vital Signs Results	Update CDISC Definition	A basic unit of thermodynamic temperature, one of the seven base units of the International System of Units (Systeme International d'Unites, SI). It is 1/273.16th of the thermodynamic temperature of the triple point of water, This sets the size of the kelvin unit for temperature differences and defines the thermodynamic temperature of an equilibrium mixture of waters ice-liquid-vapor as 273.16 K, where 0 K is the lowest possible temperature ("absolute zero").	A basic unit of thermodynamic temperature, one of the seven base units of the International System of Units (Systeme International d'Unites, SI). It is 1/273.16th of the thermodynamic temperature of the triple point of water. This sets the size of the kelvin unit for temperature differences and defines the thermodynamic temperature of an equilibrium mixture of waters ice-liquid-vapor as 273.16 K, where 0 K is the lowest possible temperature ("absolute zero").	
2018-09-28	CDISC-3369; CDISC-3440	Add	C154891	Term	VSTEST	Vital Signs Test Name	Add new term to existing codelist	- - -	Neck Circumference	
2018-09-28	CDISC-3369; CDISC-3440	Add	C154891	Term	VSTESTCD	Vital Signs Test Code	Add new term to existing codelist	- - -	NECKCIR