Release Date Request Code Change Type NCI Code CDISC Term Type CDISC Codelist (Short Name) CDISC Codelist (Long Name) Change Summary Original New Change Implementation Instructions 2017-03-31 N/A Update C17668 NCI Preferred Term COUNTRY Country Update NCI Preferred Term Czech Republic Czechia 2017-03-31 N/A Update C66786 NCI Preferred Term COUNTRY Country Update NCI Preferred Term CDISC SDTM Country Terminology CDISC SEND Country Terminology 2017-03-31 CDISC-2577 Add C132355 Term EGMETHOD ECG Test Method Add new term to existing codelist - - - 6 LEAD NEHB-SPORI 2017-03-31 CDISC-2577 Add C132356 Term EGMETHOD ECG Test Method Add new term to existing codelist - - - 8 LEAD STANDARD 2017-03-31 CDISC-2710 Update C96301 CDISC Definition FXFINDRS Fetal Pathology Findings Result Update CDISC Definition No abnormalities detected. No noteworthy findings. 2017-03-31 CDISC-2710 Update C96301 CDISC Synonym FXFINDRS Fetal Pathology Findings Result Remove CDISC Synonym Normal Appearance - - - 2017-03-31 CDISC-2710 Update C96301 CDISC Synonym FXFINDRS Fetal Pathology Findings Result Remove CDISC Synonym Within Normal Limits - - - 2017-03-31 CDISC-1132 Remove C103404 Term LBTEST Laboratory Test Name Remove term entirely from codelist Hepatitis B DNA - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2655 Update C111305 CDISC Synonym LBTEST Laboratory Test Name Remove CDISC Synonym PRA - - - 2017-03-31 CDISC-2655 Update C111305 CDISC Synonym LBTEST Laboratory Test Name Remove CDISC Synonym Plasma Renin Activity - - - 2017-03-31 CDISC-2655 Update C111305 CDISC Synonym LBTEST Laboratory Test Name Remove CDISC Synonym URA - - - 2017-03-31 CDISC-2655 Update C111305 CDISC Synonym LBTEST Laboratory Test Name Remove CDISC Synonym Urinary Renin Activity - - - 2017-03-31 CDISC-2655 Update C112219 CDISC Synonym LBTEST Laboratory Test Name Remove CDISC Synonym Ghrelin - - - 2017-03-31 CDISC-2732 Update C116210 CDISC Definition LBTEST Laboratory Test Name Update CDISC Definition A measurement of the panel reactive antibody (the reactivity between host immune cells and donor human leukocyte antigen) in a biological specimen. A measurement of the panel reactive antibody that is achieved by mixing and assessing the reactivity between the recipient’s immune cells and the donor’s human leukocyte antigen, in which anti-HLA class I and class II antibody specificities are measured separately in a biological specimen. 2017-03-31 CDISC-2732 Update C116210 CDISC Synonym LBTEST Laboratory Test Name Remove CDISC Synonym Percent Panel Reactive Antibody - - - 2017-03-31 CDISC-2650 Add C132301 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Ribonucleic Acid 2017-03-31 CDISC-2395 Add C132363 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Adiponectin, High Molecular Weight 2017-03-31 CDISC-2702 Add C132364 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Alpha-Methylacyl Coenzyme A Racemase 2017-03-31 CDISC-2702 Add C132365 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - AMACR mRNA 2017-03-31 CDISC-2468; CDISC-2469 Add C132366 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Squamous Epithelial Cells/Total Cells 2017-03-31 CDISC-2702 Add C132367 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Folate Hydrolase mRNA 2017-03-31 CDISC-2632 Add C132368 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - G6PD-Deficient Erythrocytes 2017-03-31 CDISC-2632 Add C132369 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - G6PD-Deficient Erythrocytes/Erythrocytes 2017-03-31 CDISC-2432 Add C132370 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - 1,3-Beta-D-Glucan 2017-03-31 CDISC-2400 Add C132371 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Glycerol 2017-03-31 CDISC-2451 Add C132372 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Keyhole Limpet Hemocyanin IgG Antibody 2017-03-31 CDISC-2451 Add C132373 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Keyhole Limpet Hemocyanin IgM Antibody 2017-03-31 CDISC-2702 Add C132374 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Kallikrein-2 2017-03-31 CDISC-2321; CDISC-2591 Add C132375 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Lymphotoxin Alpha 2017-03-31 CDISC-2496 Add C132376 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Neutrophilic Toxic Change 2017-03-31 CDISC-2235 Add C132377 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Oncostatin M 2017-03-31 CDISC-2702 Add C132378 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - PCA3 mRNA/PSA mRNA 2017-03-31 CDISC-2702 Add C132379 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Prostate Cancer Antigen 3 mRNA 2017-03-31 CDISC-2382 Add C132380 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Platelet Mass Distribution Width 2017-03-31 CDISC-2518 Add C132381 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Calculated Panel Reactive Antibody 2017-03-31 CDISC-2702 Add C132382 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Prostate Circulating Tumor Cells 2017-03-31 CDISC-2702 Add C132383 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Prostate Specific Antigen, Free 2017-03-31 CDISC-2702 Add C132384 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - PSA, Free/PSA 2017-03-31 CDISC-2702 Add C132385 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Prostate Specific Antigen mRNA 2017-03-31 CDISC-2438; CDISC-2439 Add C132386 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Soluble Intercell Adhesion Molecule 1 2017-03-31 CDISC-1940 Add C132387 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - T-Kininogen 2017-03-31 CDISC-2454; CDISC-2455 Add C132388 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Treponema pallidum Antibody 2017-03-31 CDISC-2235 Add C132389 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Vascular Endothelial Growth Factor A 2017-03-31 CDISC-2732 Update C17634 CDISC Definition LBTEST Laboratory Test Name Update CDISC Definition A measurement of the prostate specific antigen in a biological specimen. A measurement of the total prostate specific antigen in a biological specimen. 2017-03-31 CDISC-2655 Update C74774 CDISC Synonym LBTEST Laboratory Test Name Remove CDISC Synonym Epithelial Cells - - - 2017-03-31 CDISC-2732 Update C74839 CDISC Definition LBTEST Laboratory Test Name Update CDISC Definition A measurement of the adiponectin hormone in a biological specimen. A measurement of the total adiponectin hormone in a biological specimen. 2017-03-31 CDISC-1132; CDISC-2039 Remove C92272 Term LBTEST Laboratory Test Name Remove term entirely from codelist Hepatitis G RNA - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C92273 Term LBTEST Laboratory Test Name Remove term entirely from codelist Influenza A H1N1 Viral Load - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C92274 Term LBTEST Laboratory Test Name Remove term entirely from codelist Influenza A Viral Load - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C92541 Term LBTEST Laboratory Test Name Remove term entirely from codelist HAV Viral Load - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-1132; CDISC-2039 Remove C92542 Term LBTEST Laboratory Test Name Remove term entirely from codelist HBV Viral Load - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C92543 Term LBTEST Laboratory Test Name Remove term entirely from codelist HCV Viral Load - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C92544 Term LBTEST Laboratory Test Name Remove term entirely from codelist HIV Viral Load - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C98705 Term LBTEST Laboratory Test Name Remove term entirely from codelist ADV Viral Load - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C98710 Term LBTEST Laboratory Test Name Remove term entirely from codelist BKV Viral Load - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C98716 Term LBTEST Laboratory Test Name Remove term entirely from codelist CMV Viral Load - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C98721 Term LBTEST Laboratory Test Name Remove term entirely from codelist EBV Viral Load - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-1132 Remove C103404 Term LBTESTCD Laboratory Test Code Remove term entirely from codelist HBDNA - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2655 Update C111305 CDISC Synonym LBTESTCD Laboratory Test Code Remove CDISC Synonym PRA - - - 2017-03-31 CDISC-2655 Update C111305 CDISC Synonym LBTESTCD Laboratory Test Code Remove CDISC Synonym Plasma Renin Activity - - - 2017-03-31 CDISC-2655 Update C111305 CDISC Synonym LBTESTCD Laboratory Test Code Remove CDISC Synonym URA - - - 2017-03-31 CDISC-2655 Update C111305 CDISC Synonym LBTESTCD Laboratory Test Code Remove CDISC Synonym Urinary Renin Activity - - - 2017-03-31 CDISC-2655 Update C112219 CDISC Synonym LBTESTCD Laboratory Test Code Remove CDISC Synonym Ghrelin - - - 2017-03-31 CDISC-2732 Update C116210 CDISC Submission Value LBTESTCD Laboratory Test Code Update CDISC Submission Value PRA PRAB 2017-03-31 CDISC-2732 Update C116210 CDISC Definition LBTESTCD Laboratory Test Code Update CDISC Definition A measurement of the panel reactive antibody (the reactivity between host immune cells and donor human leukocyte antigen) in a biological specimen. A measurement of the panel reactive antibody that is achieved by mixing and assessing the reactivity between the recipient’s immune cells and the donor’s human leukocyte antigen, in which anti-HLA class I and class II antibody specificities are measured separately in a biological specimen. 2017-03-31 CDISC-2732 Update C116210 CDISC Synonym LBTESTCD Laboratory Test Code Remove CDISC Synonym Percent Panel Reactive Antibody - - - 2017-03-31 CDISC-2650 Add C132301 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - RNA 2017-03-31 CDISC-2395 Add C132363 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - ADPNHMW 2017-03-31 CDISC-2702 Add C132364 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - AMACR 2017-03-31 CDISC-2702 Add C132365 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - AMCRMRNA 2017-03-31 CDISC-2468; CDISC-2469 Add C132366 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - EPISCECE 2017-03-31 CDISC-2702 Add C132367 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - FOLHMRNA 2017-03-31 CDISC-2632 Add C132368 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - G6PDRBC 2017-03-31 CDISC-2632 Add C132369 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - G6PDRBRB 2017-03-31 CDISC-2432 Add C132370 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - GLUBD13 2017-03-31 CDISC-2400 Add C132371 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - GLYCRL 2017-03-31 CDISC-2451 Add C132372 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - KLHIGGAB 2017-03-31 CDISC-2451 Add C132373 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - KLHIGMAB 2017-03-31 CDISC-2702 Add C132374 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - KLK2 2017-03-31 CDISC-2321; CDISC-2591 Add C132375 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - LTA 2017-03-31 CDISC-2496 Add C132376 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - NEUTTOXC 2017-03-31 CDISC-2235 Add C132377 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - OSM 2017-03-31 CDISC-2702 Add C132378 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - PC3MPSAM 2017-03-31 CDISC-2702 Add C132379 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - PCA3MRNA 2017-03-31 CDISC-2382 Add C132380 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - PMDW 2017-03-31 CDISC-2518 Add C132381 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - PRABC 2017-03-31 CDISC-2702 Add C132382 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - PRCTC 2017-03-31 CDISC-2702 Add C132383 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - PSAF 2017-03-31 CDISC-2702 Add C132384 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - PSAFPSAT 2017-03-31 CDISC-2702 Add C132385 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - PSAMRNA 2017-03-31 CDISC-2438; CDISC-2439 Add C132386 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - SICAM1 2017-03-31 CDISC-1940 Add C132387 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - TKG 2017-03-31 CDISC-2454; CDISC-2455 Add C132388 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - TPLAB 2017-03-31 CDISC-2235 Add C132389 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - VEGFA 2017-03-31 CDISC-2732 Update C17634 CDISC Definition LBTESTCD Laboratory Test Code Update CDISC Definition A measurement of the prostate specific antigen in a biological specimen. A measurement of the total prostate specific antigen in a biological specimen. 2017-03-31 CDISC-2655 Update C74774 CDISC Synonym LBTESTCD Laboratory Test Code Remove CDISC Synonym Epithelial Cells - - - 2017-03-31 CDISC-2732 Update C74839 CDISC Definition LBTESTCD Laboratory Test Code Update CDISC Definition A measurement of the adiponectin hormone in a biological specimen. A measurement of the total adiponectin hormone in a biological specimen. 2017-03-31 CDISC-1132; CDISC-2039 Remove C92272 Term LBTESTCD Laboratory Test Code Remove term entirely from codelist HGRNA - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C92273 Term LBTESTCD Laboratory Test Code Remove term entirely from codelist IAH1N1VL - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C92274 Term LBTESTCD Laboratory Test Code Remove term entirely from codelist INFAVLD - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C92541 Term LBTESTCD Laboratory Test Code Remove term entirely from codelist HAVVLD - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-1132; CDISC-2039 Remove C92542 Term LBTESTCD Laboratory Test Code Remove term entirely from codelist HBVVLD - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C92543 Term LBTESTCD Laboratory Test Code Remove term entirely from codelist HCVVLD - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C92544 Term LBTESTCD Laboratory Test Code Remove term entirely from codelist HIVVLD - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C98705 Term LBTESTCD Laboratory Test Code Remove term entirely from codelist ADVVLD - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C98710 Term LBTESTCD Laboratory Test Code Remove term entirely from codelist BKVVLD - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C98716 Term LBTESTCD Laboratory Test Code Remove term entirely from codelist CMVVLD - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2039 Remove C98721 Term LBTESTCD Laboratory Test Code Remove term entirely from codelist EBVVLD - - - As per Virology TAUG, Viral Load should go into the LBCAT variable. The LBTEST variable can contain RNA, DNA, etc. The new variable NHOID holds the non-host organism identifier. 2017-03-31 CDISC-2710 Update C117736 CDISC Definition LOC Anatomical Location Update CDISC Definition The portion of the quadriceps femoris muscle group that extends medially from the intertrochanteric line of the femur to the medial aspects of the quadriceps femoris tendon and patella. (NCI) A muscle in the quadriceps femoris muscle group medial to the vastus intermedius; primary function is the extension of the femorotibial joint. 2017-03-31 CDISC-2710 Update C117876 CDISC Definition LOC Anatomical Location Update CDISC Definition The portion of the quadriceps femoris muscle group that is underneath the Rectus Femoris muscle, spans and covers the upper two-thirds of the anterior and lateral surfaces of the femur, and inserts into the lateral border of the patella. A muscle in the quadriceps femoris muscle group between the vastus lateralis and vastus medialis deep to the rectus femoris; primary function is the extension of the femorotibial joint. 2017-03-31 CDISC-2323 Add C118775 Term LOC Anatomical Location Add new term to existing codelist - - - AORTOCAVAL LYMPH NODE 2017-03-31 CDISC-1741 Update C12230 CDISC Definition LOC Anatomical Location Update CDISC Definition The bony anterior part of the roof of the mouth separating the nose from the mouth. (NCI) The part of the roof of the mouth supported by bone. 2017-03-31 CDISC-1741 Update C12230 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Hard Palate - - - 2017-03-31 CDISC-1741 Update C12231 CDISC Definition LOC Anatomical Location Update CDISC Definition A movable fold suspended from the posterior border of the hard palate. (MeSH) The part of the roof of the mouth not supported by bone. 2017-03-31 CDISC-2331 Update C12256 CDISC Definition LOC Anatomical Location Update CDISC Definition The area around the esophagogastric mucosal junction where the esophageal mucosa transitions into the gastric mucosa. (NCI) The region of the stomach adjacent to the esophogastric junction. 2017-03-31 CDISC-2331 Update C12256 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Gastric Cardia - - - 2017-03-31 CDISC-2331 Update C12257 CDISC Definition LOC Anatomical Location Update CDISC Definition The portion of the stomach that lies above the cardiac notch. It allows for the accumulation of gases produced by chemical digestion. (NCI) The blind sac region of the glandular stomach. 2017-03-31 CDISC-2331 Update C12257 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Fundus of the Stomach - - - 2017-03-31 CDISC-2331 Update C12263 CDISC Definition LOC Anatomical Location Update CDISC Definition A jointed tube 25-30 cm long that connects the stomach to the jejunum. (NCI) The portion of the small intestine between the stomach and jejunum. 2017-03-31 CDISC-1741 Update C12274 CDISC Definition LOC Anatomical Location Update CDISC Definition The part of the ear including the eardrum and ossicles. The middle ear leads to the inner ear. (NCI) The part of the ear including the eardrum and ossicles. 2017-03-31 CDISC-1741 Update C12274 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Middle Ear - - - 2017-03-31 CDISC-1741 Update C12298 CDISC Definition LOC Anatomical Location Update CDISC Definition The back of the abdomen where the kidneys lie and the great blood vessels run. (NCI) The region of the abdomen outside the peritoneum, where the kidneys lie and the great blood vessels run. 2017-03-31 CDISC-1741 Update C12298 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym RETROPERITONEAL CAVITY - - - 2017-03-31 CDISC-1741 Update C12299 CDISC Definition LOC Anatomical Location Update CDISC Definition The pigmented protuberance on the surface of the breast through which milk is drawn from the breast. (NCI) The protuberance in the skin where the ducts of the mammary gland open. 2017-03-31 CDISC-1741 Update C12299 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Nipple - - - 2017-03-31 CDISC-1348 Update C12311 CDISC Definition LOC Anatomical Location Update CDISC Definition The lower part of the uterus occupying the region between the isthmus of the uterus and the vagina. It is divided into supravaginal and vaginal portions. (NCI) The portion of the uterus (or uterine horns) that empties into the vagina. 2017-03-31 CDISC-1543 Update C12328 CDISC Definition LOC Anatomical Location Update CDISC Definition A crescent-like structure located in the upper and posterior surfaces of the testis. It consists of the efferent ductules and the duct of the epididymis. It facilitates the maturation of sperm that is produced in the testis. (NCI) A crescent-like structure located adjacent to the testis. It consists of a single highly coiled duct and is divided into 3 regions: caput (head), corpus (body) and cauda (tail). 2017-03-31 CDISC-1543 Update C12341 CDISC Definition LOC Anatomical Location Update CDISC Definition A thin, transparent tissue divided into the palpebral conjunctiva (covering the inner side of the eye lid) and the bulbar conjunctiva (covering the eyeball). (NCI) A thin tissue divided into the palpebral conjunctiva (covering the inner side of the eye lid) and the bulbar conjunctiva (covering the eyeball). (NCI) 2017-03-31 CDISC-1543 Update C12341 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Conjunctiva - - - 2017-03-31 CDISC-1543 Update C12342 CDISC Definition LOC Anatomical Location Update CDISC Definition A dome-shaped, transparent, avascular tissue covering the front of the eye. It is composed of five layers: squamous epithelium, Bowman's membrane, stroma, Descemet's membrane, and endothelium. Refraction of light contributing to eye's focusing ability is its characteristic function. It contains unmyelinated nerve endings which are responsible for the high sensitivity of the tissue. (NCI) The transparent, avascular tissue covering the front of the eye and is continuous with the sclera. 2017-03-31 CDISC-1543 Update C12342 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Cornea - - - 2017-03-31 CDISC-1543 Update C12345 CDISC Definition LOC Anatomical Location Update CDISC Definition Tissue located behind the iris and composed of muscle and epithelium. Its functions include the production of aqueous humor and changing the shape of the crystalline lens. (NCI) Circumferential tissue located behind the iris and composed of muscle and epithelium. 2017-03-31 CDISC-1670; CDISC-1699 Update C12346 CDISC Definition LOC Anatomical Location Update CDISC Definition Paired, almond-shaped exocrine glands situated superior and posterior to each orbit of the eye that produce and secrete the watery serous component of tears. (NCI) The exocrine glands that produce the watery serous component of tears. 2017-03-31 CDISC-1741 Update C12347 CDISC Definition LOC Anatomical Location Update CDISC Definition The bony cavity of the skull which contains the eye, anterior portion of the optic nerve, ocular muscles and ocular adnexa. Seven bones contribute to the structure of the orbit: the frontal, maxillary, zygomatic, sphenoid, lacrimal, ethmoid, and palatine bones. (NCI) The bony cavity that contains the eye and its associated structures. 2017-03-31 CDISC-1741 Update C12347 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Orbital Cavity - - - 2017-03-31 CDISC-1348 Update C12351 CDISC Definition LOC Anatomical Location Update CDISC Definition One half of the cerebrum, the part of the brain that controls muscle functions and also controls speech, thought, emotions, reading, writing, and learning. The right hemisphere controls the muscles on the left side of the body, and the left hemisphere controls the muscles on the right side of the body. (NCI) The portion of the brain comprising the frontal, parietal, temporal, and occipital lobes and extending through the thalamus. 2017-03-31 CDISC-1348 Update C12351 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Cerebral Hemisphere - - - 2017-03-31 CDISC-1348 Update C12366 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Bone - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12367 CDISC Definition LOC Anatomical Location Update CDISC Definition Lactiferous glands consisting of fibrous tissue connecting the lobes and fatty tissue in between the lobes. The exocrine glands of the mammae that produce milk in females, and are composed of lobules, alveolar ducts and alveoli. 2017-03-31 CDISC-2258 Add C12375 Term LOC Anatomical Location Add new term to existing codelist - - - ANAL CANAL 2017-03-31 CDISC-1670; CDISC-1699 Update C12377 CDISC Definition LOC Anatomical Location Update CDISC Definition A pear-shaped organ located under the liver that stores and concentrates bile secreted by the liver. From the gallbladder the bile is delivered through the bile ducts into the intestine thereby aiding the digestion of fat-containing foods. (NCI) A sac-like organ located adjacent to the liver that stores and concentrates bile produced by the liver. 2017-03-31 CDISC-1670; CDISC-1699 Update C12377 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Gallbladder - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12379 CDISC Definition LOC Anatomical Location Update CDISC Definition A muscular tube that extends from the end of the small intestine to the anus. (NCI) The avillous section of the intestine composed of crypts and extending from the terminal small intestine to the external orifice. 2017-03-31 CDISC-1670; CDISC-1699 Update C12379 CDISC Synonym LOC Anatomical Location Add new CDISC Synonym - - - Large Bowel 2017-03-31 CDISC-1670; CDISC-1699 Update C12379 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Large Intestine - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12380 CDISC Definition LOC Anatomical Location Update CDISC Definition Small tissue projection existing as a cecal diverticulum with a questionable history of vestigial versus specialized organ. (NCI) A pouch-like tissue attached to the cecum, which may exist as a diverticulum. 2017-03-31 CDISC-1670; CDISC-1699 Update C12380 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Appendix - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12381 CDISC Definition LOC Anatomical Location Update CDISC Definition A blind pouch-like commencement of the colon in the right lower quadrant of the abdomen at the end of the small intestine and the start of the large intestine. (OMD) The pouch-like portion of the proximal large intestine opening into the colon. 2017-03-31 CDISC-1670; CDISC-1699 Update C12381 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Cecal - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12381 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Cecum - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12382 CDISC Definition LOC Anatomical Location Update CDISC Definition The part of the large intestine measured from the cecum to the rectum consisting of ascending, transverse, descending and sigmoid portions. The purpose of the colon is to remove water from digested food prior to excretion. (NCI) The portion of the large intestine which extends from the cecum (or small intestine in animals that don't have a cecum) to the rectum. 2017-03-31 CDISC-1670; CDISC-1699 Update C12382 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Colon - - - 2017-03-31 CDISC-2363; CDISC-2331 Update C12386 CDISC Definition LOC Anatomical Location Update CDISC Definition The section of the intestines between the pylorus and cecum. The small intestine consists of the duodenum, the jejunum, and the ileum. The villous section of the intestine extending from the pylorus to the proximal large intestine. 2017-03-31 CDISC-2331 Update C12387 CDISC Definition LOC Anatomical Location Update CDISC Definition The final section of the small intestine. (NCI) The portion of the small intestine between the jejunum and large intestine. 2017-03-31 CDISC-2331 Update C12387 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Ileum - - - 2017-03-31 CDISC-2331 Update C12388 CDISC Definition LOC Anatomical Location Update CDISC Definition The portion of the small intestine that extends from the duodenum to the ileum. (NCI) The portion of the small intestine between the duodenum and ileum. 2017-03-31 CDISC-2331 Update C12388 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Jejunum - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12390 CDISC Definition LOC Anatomical Location Update CDISC Definition The terminal portion of the gastrointestinal tract, extending from the rectosigmoid junction to the anal canal. (NCI) The terminal portion of the large intestine extending from the terminus of the colon to the anus or anal canal. 2017-03-31 CDISC-2363 Update C12391 CDISC Definition LOC Anatomical Location Update CDISC Definition An organ located under the diaphragm, between the liver and the spleen as well as between the esophagus and the small intestine. The stomach is the primary organ of food digestion. (NCI) The portion of the gastrointestinal tract located between the esophagus and the proximal duodenum. 2017-03-31 CDISC-2363 Update C12391 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Stomach - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12392 CDISC Definition LOC Anatomical Location Update CDISC Definition An abdominal organ that has variable lobation which are composed of hepatic lobules. An abdominal organ that has variable lobation which are composed mainly of hepatic lobules. 2017-03-31 CDISC-1741 Update C12393 CDISC Definition LOC Anatomical Location Update CDISC Definition An organ located adjacent to the stomach that contains both exocrine and endocrine tissue. A digestive organ in the abdomen that has both endocrine and exocrine functions. 2017-03-31 CDISC-1543 Update C12394 CDISC Definition LOC Anatomical Location Update CDISC Definition A sense organ needed for the detection of sound and for establishing balance. The outer ear consists of the auricle, the ear canal as well as the tympanic membrane. The middle ear is made up of an air-filled cavity behind the tympanic membrane that contains the ossicles (malleus, incus and stapes). The inner ear is made up of the cochlea needed for hearing and the vestibular apparatus required for balance. (NCI) A sensory organ that contains auditory and vestibular apparatuses. 2017-03-31 CDISC-1543 Update C12394 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Ear - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12398 CDISC Definition LOC Anatomical Location Update CDISC Definition A small endocrine gland within the diencephalon of the brain, situated beneath the back part of the corpus callosum, that secretes melatonin. A small endocrine gland that arises from the central posterior aspect of the diencephalon. 2017-03-31 CDISC-1670; CDISC-1699 Update C12398 CDISC Synonym LOC Anatomical Location Add new CDISC Synonym - - - Pineal Body 2017-03-31 CDISC-1670; CDISC-1699 Update C12399 CDISC Definition LOC Anatomical Location Update CDISC Definition Pea-sized endocrine gland located at the base of the brain in the pituitary fossa. It produces and secretes hormones such as oxytocin and vasopressin, to regulate the activities of the hypothalamus. (NCI) A small endocrine gland extending from the hypothalamus at the base of the brain. 2017-03-31 CDISC-1670; CDISC-1699 Update C12400 CDISC Definition LOC Anatomical Location Update CDISC Definition An endocrine gland located at the base of the neck that produces and secretes thyroxine and other hormones. Thyroxine is important for metabolic control. (NCI) Endocrine gland(s) adjacent to the trachea in mammals that produce thyroxine and other hormones. 2017-03-31 CDISC-1670; CDISC-1699 Update C12400 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Thyroid Gland - - - 2017-03-31 CDISC-1543 Update C12401 CDISC Definition LOC Anatomical Location Update CDISC Definition The organ of sight or vision. (NCI) The sensory organ of vision. 2017-03-31 CDISC-1543 Update C12401 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Eye - - - 2017-03-31 CDISC-1741 Update C12403 CDISC Definition LOC Anatomical Location Update CDISC Definition One of a pair of tubes that extend from the uterus to each of the ovaries. Following ovulation the egg travels down the fallopian tube to the uterus where fertilization may or may not occur. (NCI) The tube through which eggs pass from an ovary. 2017-03-31 CDISC-1741 Update C12404 CDISC Definition LOC Anatomical Location Update CDISC Definition One of the paired female reproductive glands containing the ova or germ cells; the ovary's stroma is a vascular connective tissue containing numbers of ovarian follicles enclosing the ova. (NCI) The female gonad. 2017-03-31 CDISC-1741 Update C12404 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Ovary - - - 2017-03-31 CDISC-2331 Update C12408 CDISC Definition LOC Anatomical Location Update CDISC Definition The external, visible part of the female genitalia surrounding the urethral and vaginal opening. The vulva includes the clitoris and inner as well as outer labia. (NCI) The external, visible part of the female genitalia surrounding the urethral and vaginal opening(s). 2017-03-31 CDISC-2331 Update C12408 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym External Genitalia - - - 2017-03-31 CDISC-2331 Update C12408 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Vulva - - - 2017-03-31 CDISC-1741 Update C12409 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Penis - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12410 CDISC Definition LOC Anatomical Location Update CDISC Definition The walnut shaped accessory sex gland of the male reproductive system. It is located in the pelvis just below the bladder, surrounding the prostatic part of the urethra. The prostate gland secretes a fluid which is part of the semen. (NCI) The male reproductive accessory gland that produces prostatic fluid and is located adjacent to or around the urethra distal to the urinary bladder in mammals. 2017-03-31 CDISC-1670; CDISC-1699 Update C12410 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Prostate Gland - - - 2017-03-31 CDISC-2710 Update C12412 CDISC Definition LOC Anatomical Location Update CDISC Definition Either of the paired male reproductive glands that produce the male germ cells and the male hormones. (NCI) The male gonad. 2017-03-31 CDISC-2710 Update C12412 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Testis - - - 2017-03-31 CDISC-1348 Update C12414 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Bladder - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12415 CDISC Definition LOC Anatomical Location Update CDISC Definition One of the two bean-shaped organs located on each side of the spine in the retroperitoneum. The right kidney is located below the liver and the left kidney below the diaphragm. The kidneys filter and secret the metabolic products and minerals from the blood, thus maintaining the homeostasis. On the superior pole of each kidney there is an adrenal gland. Each kidney and adrenal gland is surrounded by fat. (NCI) The organs of the urinary tract located in the retroperitoneal cavity adjacent to the spine and composed of the renal cortex and the renal medulla. 2017-03-31 CDISC-1670; CDISC-1699 Update C12415 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Kidney - - - 2017-03-31 CDISC-2331 Update C12416 CDISC Definition LOC Anatomical Location Update CDISC Definition The thick-walled tube that carries urine from each kidney to the bladder. (NCI) The tube that extends from each kidney to the urinary bladder. 2017-03-31 CDISC-2331 Update C12416 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Ureter - - - 2017-03-31 CDISC-2331 Update C12417 CDISC Definition LOC Anatomical Location Update CDISC Definition The tube carrying urine from the bladder to outside of the body. (NCI) The tube that extends from the urinary bladder to the urethral opening. 2017-03-31 CDISC-2331 Update C12417 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Urethra - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12419 CDISC Definition LOC Anatomical Location Update CDISC Definition The anterior and superior part of a human or animal bearing the mouth, the brain and sensory organs. The portion of the body containing the mouth, the brain and multiple sensory organs. 2017-03-31 CDISC-1670; CDISC-1699 Update C12419 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Head - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12420 CDISC Definition LOC Anatomical Location Update CDISC Definition The cartilaginous structure of the respiratory tract between the pharynx and the trachea. It contains elastic vocal cords required for sound production. (NCI) The cartilaginous structure of the respiratory tract between the pharynx and the trachea. 2017-03-31 CDISC-1670; CDISC-1699 Update C12420 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Larynx - - - 2017-03-31 CDISC-1348 Update C12421 CDISC Definition LOC Anatomical Location Update CDISC Definition The cavity located at the upper end of the alimentary canal, behind the teeth and gums that is bounded on the outside by the lips, above by the hard and soft palates and below by the tongue. (NCI) The cavity of the mouth. 2017-03-31 CDISC-1348 Update C12421 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Oral Cavity - - - 2017-03-31 CDISC-2331 Update C12422 CDISC Definition LOC Anatomical Location Update CDISC Definition The muscular organ located in the floor of the mouth and serving as the principal organ of taste and modification of the voice in speech. (NCI) The muscular organ in the mouth used in taste perception and food ingestion. 2017-03-31 CDISC-2331 Update C12422 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Tongue - - - 2017-03-31 CDISC-1741 Update C12423 CDISC Definition LOC Anatomical Location Update CDISC Definition The part of the pharynx in the back of the throat, at and above the soft palate. The nasopharynx is continuous with the nasal passages. (NCI) The part of the pharynx above the soft palate, which is continuous with the nasal cavity and extends to the oropharynx. 2017-03-31 CDISC-1741 Update C12423 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Nasopharynx - - - 2017-03-31 CDISC-1348 Update C12424 CDISC Definition LOC Anatomical Location Update CDISC Definition The proximal portion of the respiratory passages on either side of the nasal septum lying between the floor of the cranium and the roof of the mouth and extending from the face to the pharynx. The nasal cavity is lined with ciliated mucosa, extending from the nares to the pharynx. (NCI) The upper respiratory tract extending from the nares to the pharynx. 2017-03-31 CDISC-1348 Update C12424 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Nasal Cavity - - - 2017-03-31 CDISC-1741 Update C12425 CDISC Definition LOC Anatomical Location Update CDISC Definition A hollow tube that starts posterior to the mouth and nasal cavity and ends superior to the trachea and esophagus. (NCI) A passageway in the head and neck that includes the nasopharynx, oropharynx and laryngopharynx. 2017-03-31 CDISC-1741 Update C12425 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Pharynx - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12426 CDISC Definition LOC Anatomical Location Update CDISC Definition An exocrine gland that secretes saliva. Salivary glands are mostly located in and around the oral cavity. Any number of exocrine glands that secrete saliva into the oral cavity. 2017-03-31 CDISC-1670; CDISC-1699 Update C12427 CDISC Definition LOC Anatomical Location Update CDISC Definition The largest of the three paired salivary glands, located in front of the ear. (NCI) The salivary gland located adjacent to the ear. 2017-03-31 CDISC-1670; CDISC-1699 Update C12427 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Parotid Gland - - - 2017-03-31 CDISC-2331 Update C12428 CDISC Definition LOC Anatomical Location Update CDISC Definition The fibrocartilaginous, mucous-lined tube passing from the larynx to the bronchi. (NCI) The fibrocartilaginous tube extending from the larynx to the bronchi. 2017-03-31 CDISC-2331 Update C12428 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Trachea - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12429 CDISC Definition LOC Anatomical Location Update CDISC Definition A body region referring to an upper or lower extremity. (NCI) A jointed extremity of the upper/thoracic or lower/pelvic regions. 2017-03-31 CDISC-1670; CDISC-1699 Update C12429 CDISC Synonym LOC Anatomical Location Add new CDISC Synonym - - - Extremity 2017-03-31 CDISC-1670; CDISC-1699 Update C12429 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Extremities - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12429 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Limb - - - 2017-03-31 CDISC-1348 Update C12431 CDISC Definition LOC Anatomical Location Update CDISC Definition The tissue occupying the spaces of bone. It consists of blood vessel sinuses and a network of hematopoietic cells which give rise to the red cells, white cells, and megakaryocytes. (NCI) The tissue occupying the spaces of some bones. It consists of blood vessel sinuses and a network of hematopoietic cells. 2017-03-31 CDISC-1348 Update C12431 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Bone Marrow - - - 2017-03-31 CDISC-2363; CDISC-2331 Update C12433 CDISC Definition LOC Anatomical Location Update CDISC Definition A lymphoid organ located in the thorax near the thoracic inlet and/or neck, essential for the development of the immune system. A primary lymphoid organ generally located in the mediastinum near the thoracic inlet and/or along lateral aspects of the neck. 2017-03-31 CDISC-1348 Update C12440 CDISC Definition LOC Anatomical Location Update CDISC Definition An almond-shaped group of basal nuclei anterior to the inferior horn of the lateral ventricle of the brain, within the temporal lobe. The amygdala is part of the limbic system. (MESH) A group of nuclei adjacent to the lateral ventricle of the brain within the temporal lobe, and is part of the limbic system. 2017-03-31 CDISC-1348 Update C12440 CDISC Synonym LOC Anatomical Location Add new CDISC Synonym - - - Amygdala 2017-03-31 CDISC-1348 Update C12440 CDISC Synonym LOC Anatomical Location Add new CDISC Synonym - - - Amygdaloid Body 2017-03-31 CDISC-1348 Update C12442 CDISC Definition LOC Anatomical Location Update CDISC Definition The lower portion of the brainstem located between the pons and brainstem. This structure contains several descending and ascending tracts, lower cranial nerve nuclei, a significant proportion of the reticular system of the brainstem and other structures. (NCI) The portion of the brainstem between the pons and cervical spinal cord. 2017-03-31 CDISC-1348 Update C12442 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Medulla Oblongata - - - 2017-03-31 CDISC-1348 Update C12444 CDISC Definition LOC Anatomical Location Update CDISC Definition A curved gray matter structure of the temporal lobe lying on the floor of the lateral ventricle of the brain. (NCI) A curved gray matter structure of the cerebrum that is part of the limbic system. 2017-03-31 CDISC-1348 Update C12444 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Hippocampus - - - 2017-03-31 CDISC-1348 Update C12445 CDISC Definition LOC Anatomical Location Update CDISC Definition The portion of the brain located at the base of the skull that is responsible for balance, equilibrium and movement. (NCI) The portion of the brain that extends from the brainstem through the cerebellar folia. 2017-03-31 CDISC-1543 Update C12446 CDISC Definition LOC Anatomical Location Update CDISC Definition A white matter structure within the cleft that separates the left and right cerebral hemispheres in the mammalian brain. It is composed of a wide, flat bundle of 200-250 million axonal projections. (NCI) A white matter structure within the brain that connects the left and right cerebral hemispheres. 2017-03-31 CDISC-1348 Update C12447 CDISC Definition LOC Anatomical Location Update CDISC Definition Clusters of neurons comprising the globus pallidus, putamen, caudate, nucleus accumbens, substantia nigra and subthalamic nucleus. They are involved with high level aspects of inhibitory motor activity in coordination with the excitation commands issued from the cerebellum. (NCI) Clusters of neurons comprising the globus pallidus, putamen, caudate, nucleus accumbens, substantia nigra and subthalamic nucleus. 2017-03-31 CDISC-1348 Update C12447 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Basal Ganglia - - - 2017-03-31 CDISC-1348 Update C12453 CDISC Definition LOC Anatomical Location Update CDISC Definition A large cell mass extending forward, over the dorsal surface of the crus cerebri, from the rostral border of the pons into the subthalamic region. It is composed of a dorsal stratum of closely spaced pigmented cells, the pars compacta, and a larger ventral region of widely scattered cells, the pars reticulata. The pars compacta includes numerous cells that project forward to the striatum (caudate nucleus and putamen) and contain dopamine, which acts as the primary neurotransmitter at the synaptic endings. Other, apparently non-dopaminergic cells project to portions of the ventral nucleus of thalamus, the superior colliculus and reticular formation. The nigrostriatal projection is reciprocated by a striatonigral fiber system with multiple neurotransmitters, chief among which is gamma-aminobutyric acid (GABA). The substantia nigra is involved in the metabolic disturbances associated with Parkinson's disease and Huntington's disease. (NCI) The portion of the midbrain composed of two parts, the pars compacta and pars reticulata. 2017-03-31 CDISC-1348 Update C12453 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Substantia Nigra - - - 2017-03-31 CDISC-1348 Update C12458 CDISC Definition LOC Anatomical Location Update CDISC Definition The supervisory center in the brain, rich in ganglia, nerve fibers, and synaptic connections. It is composed of several sections called nuclei, each of which controls a specific function. A small region of the brain composed of multiple nuclei and located underneath the thalamus. 2017-03-31 CDISC-1348 Update C12458 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Hypothalamus - - - 2017-03-31 CDISC-1348 Update C12459 CDISC Definition LOC Anatomical Location Update CDISC Definition An ovoid mass composed predominantly of gray substance and associated laminae of white substance. The thalamus is divided into anterior, medial, and lateral parts. The function of the thalamus is to relay sensory impulses and cerebellar and basal ganglia projections to the cerebral cortex. The thalamus is positioned within the posterior part of the diencephalon forming most of each lateral wall of the third ventricle. (NCI) The portion of the diencephalon forming most of each lateral wall of the third ventricle. 2017-03-31 CDISC-1348 Update C12459 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Thalamus - - - 2017-03-31 CDISC-2331 Update C12464 CDISC Definition LOC Anatomical Location Update CDISC Definition The elongated, approximately cylindrical part of the central nervous system of vertebrates that lies in the vertebral canal and from which the spinal nerves emerge. (NCI) The portion of the central nervous system that lies within the vertebral canal and from which the spinal nerves emerge. 2017-03-31 CDISC-1741 Update C12466 CDISC Definition LOC Anatomical Location Update CDISC Definition A bundle of fibers that transmits electrochemical impulses encoding sensory and motor information from one body part to another. A bundle of neuronal fibers that transmits electrochemical impulses encoding sensory and motor information from one body part to another. 2017-03-31 CDISC-1670; CDISC-1699 Update C12468 CDISC Definition LOC Anatomical Location Update CDISC Definition An organ of respiration occupying the pulmonary cavity of the thorax, in which aeration of the blood takes place. A thoracic organ that has variable lobation and is the primary respiratory organ of mammals. 2017-03-31 CDISC-1741 Update C12469 CDISC Definition LOC Anatomical Location Update CDISC Definition The tissue that lines the wall of the thoracic cavity and the surface of the lungs. (NCI) The serous membrane that lines the wall of the thoracic cavity and the surface of the lungs. 2017-03-31 CDISC-1741 Update C12469 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Pleural Tissue - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12499 CDISC Definition LOC Anatomical Location Update CDISC Definition The portion of the ear located within the temporal bone that is involved in both hearing and balance and includes the semicircular canals, vestibule, and cochlea. (from American Heritage Dictionary online) The innermost portion of the ear that contains the vestibule, cochlea and semicircular canals. 2017-03-31 CDISC-1670; CDISC-1699 Update C12499 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Cochlea - - - 2017-03-31 CDISC-1348 Update C12510 CDISC Definition LOC Anatomical Location Update CDISC Definition The uppermost portion of the brainstem located between the pons and the diencephalon. The midbrain contains the cerebral peduncles, oculomotor, trochlear and red nuclei, substantia nigra and various other nuclei and tracts. (NCI) The portion of the brainstem between the pons and diencephalon. 2017-03-31 CDISC-1348 Update C12510 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Midbrain - - - 2017-03-31 CDISC-1348 Update C12511 CDISC Definition LOC Anatomical Location Update CDISC Definition The middle portion of the brainstem located between the midbrain and the medulla oblongata. The portion of the brainstem between the midbrain and medulla oblongata. 2017-03-31 CDISC-1348 Update C12664 CDISC Definition LOC Anatomical Location Update CDISC Definition The portion of the body that lies between the thorax and the pelvis. (NCI) The body cavity between the thoracic and pelvic cavities in mammals. 2017-03-31 CDISC-1348 Update C12664 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Abdominal Cavity - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12666 CDISC Definition LOC Anatomical Location Update CDISC Definition Suprarenal gland. A flattened, roughly triangular body resting upon the upper end of each kidney; it is one of the ductless glands furnishing internal secretions (epinephrine and norepinephrine from the medulla and steroid hormones from the cortex). (NCI) The endocrine glands adjacent to the kidneys that consist of the outer adrenal cortex and the inner adrenal medulla in mammals. 2017-03-31 CDISC-1670; CDISC-1699 Update C12666 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Adrenal Gland - - - 2017-03-31 CDISC-1543 Update C12667 CDISC Definition LOC Anatomical Location Update CDISC Definition The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109) (NCI) The space in the eye filled with aqueous humor and bounded by the cornea, a small portion of the sclera, a small portion of the ciliary body, the iris and lens. (Cline et al., Dictionary of Visual Science, 4th ed, p109) 2017-03-31 CDISC-1348 Update C12669 CDISC Definition LOC Anatomical Location Update CDISC Definition The major arterial trunk that carries oxygenated blood from the left ventricle into the ascending aorta behind the heart, the aortic arch, through the thorax as the descending aorta and through the abdomen as the abdominal aorta; it bifurcates into the left and right common iliac arteries. (NCI) The major artery of the body; it arises from the left ventricle of the heart and terminally bifurcates into the common iliac arteries. 2017-03-31 CDISC-1348 Update C12669 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Aorta - - - 2017-03-31 CDISC-2331 Update C12670 CDISC Definition LOC Anatomical Location Update CDISC Definition A valve that is located between and controls the flow of blood from the left ventricle of the heart and the aorta. (NCI) A cardiac valve located between the left ventricle and the aorta. 2017-03-31 CDISC-2363 Update C12679 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Blood Vessel - - - 2017-03-31 CDISC-1348 Update C12681 CDISC Definition LOC Anatomical Location Update CDISC Definition An artery originating at the axillary artery and branching into the radial and ulnar arteries. (NCI) An artery of the forelimb; in general it arises from the axillary artery and branches to form the radial and ulnar arteries. 2017-03-31 CDISC-1348 Update C12681 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Brachial Artery - - - 2017-03-31 CDISC-1741 Update C12682 CDISC Definition LOC Anatomical Location Update CDISC Definition A nerve network originating from C5 to T1 that supplies cutaneous and muscular innervation to the arm and hand. (NCI) A nerve network originating from spinal nerves in the cervical and thoracic vertebrae and giving rise to multiple nerves that innervate the arm/forelimb. 2017-03-31 CDISC-1348 Update C12683 CDISC Definition LOC Anatomical Location Update CDISC Definition Tubular structure in continuation with the trachea, serving as air passage. It terminates in the lung (terminal bronchiole). (NCI) Tubular structure in continuation with the trachea, serving as an air passage. 2017-03-31 CDISC-1348 Update C12683 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Bronchus - - - 2017-03-31 CDISC-1348 Update C12687 CDISC Definition LOC Anatomical Location Update CDISC Definition One of two arteries that supply oxygenated blood to the head and neck; the left common carotid branches from the aorta and the right common carotid from the innominate (brachiocephalic artery). (NCI) An artery of the mediastinum and neck; in general it arises as a primary or secondary branch of the aortic arch and branches into the internal and external carotid arteries. 2017-03-31 CDISC-1348 Update C12687 CDISC Synonym LOC Anatomical Location Add new CDISC Synonym - - - Common Carotid Artery 2017-03-31 CDISC-1348 Update C12687 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Carotid Artery - - - 2017-03-31 CDISC-1348 Update C12688 CDISC Definition LOC Anatomical Location Update CDISC Definition Any of the small bones of the wrist joint, located between the radius and the ulna and the metacarpus. (NCI) Any of the bones of the joint located between the radius and ulna and metacarpus. 2017-03-31 CDISC-1348 Update C12694 CDISC Definition LOC Anatomical Location Update CDISC Definition Blood vessels forming villous structures in the third, fourth, and lateral ventricles of the brain. (NCI) Blood vessels and ependyma forming villous structures in the ventricles of the brain. 2017-03-31 CDISC-1348 Update C12694 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Choroid Plexus - - - 2017-03-31 CDISC-1741 Update C12702 CDISC Definition LOC Anatomical Location Update CDISC Definition Fibromuscular tissue that separates the thoracic from the abdominal cavity. It increases the volume of the thoracic cavity through contractions, thus facilitating respiration. A musculotendinous sheet separating the thoracic cavity from the abdominal cavity. 2017-03-31 CDISC-1543 Update C12713 CDISC Definition LOC Anatomical Location Update CDISC Definition A thin membrane of skin with the purpose of covering and protecting an eye. (NCI) The section of skin, containing muscle and conjunctiva, that covers and protects the eye. 2017-03-31 CDISC-1543 Update C12713 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Eyelid - - - 2017-03-31 CDISC-1741 Update C12714 CDISC Definition LOC Anatomical Location Update CDISC Definition The 7th cranial nerve. The facial nerve has two parts, the larger motor root which may be called the facial nerve proper, and the smaller intermediate or sensory root. Together they provide efferent innervation to the muscles of facial expression and to the lacrimal and salivary glands, and convey afferent information for taste from the anterior two-thirds of the tongue and for touch from the external ear. (MeSH) A cranial nerve extending from the brain stem between the pons and medulla, which innervates the facial muscles, glands and the tongue. 2017-03-31 CDISC-1348 Update C12715 CDISC Definition LOC Anatomical Location Update CDISC Definition An artery that starts within the inguinal region and extends to the lower extremities. (NCI) An artery of the thigh; in general it arises from the external iliac artery distal to the inguinal ligment and continues as the popliteal artery. 2017-03-31 CDISC-1348 Update C12715 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Femoral Artery - - - 2017-03-31 CDISC-2331 Update C12716 CDISC Definition LOC Anatomical Location Update CDISC Definition A vein that starts within the inguinal region and extends to the lower extremities. (NCI) A vein of the thigh; in general it arises from the popliteal vein and drains into the external iliac vein. 2017-03-31 CDISC-2331 Update C12716 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Femoral Vein - - - 2017-03-31 CDISC-1348 Update C12717 CDISC Definition LOC Anatomical Location Update CDISC Definition The upper leg bone positioned between the pelvis and the knee. (NCI) The bone positioned between the pelvis and the femorotibial joint. 2017-03-31 CDISC-1348 Update C12717 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Femur - - - 2017-03-31 CDISC-1348 Update C12718 CDISC Definition LOC Anatomical Location Update CDISC Definition The small, lateral calf bone extending from the knee to the ankle. (NCI) The long bone that is lateral to the tibia. 2017-03-31 CDISC-1348 Update C12718 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Fibula - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12727 CDISC Definition LOC Anatomical Location Update CDISC Definition A hollow muscular organ which receives the blood from the veins and propels it into the arteries. It is divided by a musculomembranous septum into two halves -- right or venous and left or arterial -- each of which consists of a receiving chamber (atrium) and an ejecting chamber (ventricle). (NCI) A hollow muscular organ which receives the blood from the veins and pumps it into the arteries. 2017-03-31 CDISC-1670; CDISC-1699 Update C12727 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Cardiac - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12727 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Heart - - - 2017-03-31 CDISC-1348 Update C12731 CDISC Definition LOC Anatomical Location Update CDISC Definition The upper arm bone between the shoulder and elbow. (NCI) The bone between the scapulohumeral and humeroulnar joints. 2017-03-31 CDISC-1348 Update C12731 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Humerus - - - 2017-03-31 CDISC-2363 Update C12736 CDISC Definition LOC Anatomical Location Update CDISC Definition The portion of the gastrointestinal tract between the stomach and the anus. It includes the small intestine and large intestine. (NCI) The portion of the gastrointestinal tract that includes the small and large intestines. 2017-03-31 CDISC-2363 Update C12736 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Intestine - - - 2017-03-31 CDISC-1543 Update C12737 CDISC Definition LOC Anatomical Location Update CDISC Definition The colored disc of the eye composed of connective tissue, epithelium, and endothelium. It separates the anterior chamber from the posterior chamber. (NCI) The tissue in the eye that separates the anterior chamber from the posterior chamber. 2017-03-31 CDISC-2331 Update C12738 CDISC Definition LOC Anatomical Location Update CDISC Definition Veins in the neck which drain the brain, face, and neck into the brachiocephalic or subclavian veins. (NCI) One of the veins of the neck; in general it arises from the junction of the maxillary and linguofacial veins and drains into the brachiocephalic or the cranial caval vein. 2017-03-31 CDISC-1543 Update C12743 CDISC Definition LOC Anatomical Location Update CDISC Definition A biconvex transparent structure of the eye through which light is focused on the retina. The lens sits behind the iris and is supported by the zonule, which connects it to the ciliary body. The lens is an avascular structure. (NCI) The structure of the eye through which light is focused onto the retina. 2017-03-31 CDISC-1543 Update C12743 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Lens - - - 2017-03-31 CDISC-1543 Update C12743 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Lens Of Eye - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12745 CDISC Definition LOC Anatomical Location Update CDISC Definition A bean-shaped organ surrounded by a connective tissue capsule. It is part of the lymphatic system and is found through out the body. It is composed predominantly of lymphocytes and its main function is immune protection. (NCI) Secondary lymphoid organ associated with lymphatic vessels and consisting of an outer cortex, inner medulla and sinuses. 2017-03-31 CDISC-1670; CDISC-1699 Update C12745 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Lymph Node - - - 2017-03-31 CDISC-1741 Update C12748 CDISC Definition LOC Anatomical Location Update CDISC Definition A group of organs surrounded by loose connective tissue, separating the two pleural sacs, between the sternum anteriorly and the vertebral column posteriorly as well as from the thoracic inlet superiorly to the diaphragm inferiorly. The mediastinum contains the heart and pericardium, the bases of the great vessels, the trachea and bronchi, esophagus, thymus, lymph nodes, thoracic duct, phrenic and vagus nerves, and other structures and tissues. (NCI) The central region of the thoracic cavity of mammals containing a group of organs surrounded by loose connective tissue, which separates the two pleural sacs. 2017-03-31 CDISC-1741 Update C12748 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Mediastinum - - - 2017-03-31 CDISC-2331 Update C12753 CDISC Definition LOC Anatomical Location Update CDISC Definition A dual-flap valve of the heart that regulates the flow of blood between the left atrium and the left ventricle of the heart. (NCI) A cardiac valve located between the left atrium and ventricle. 2017-03-31 CDISC-2331 Update C12753 CDISC Synonym LOC Anatomical Location Add new CDISC Synonym - - - Mitral Valve 2017-03-31 CDISC-1741 Update C12760 CDISC Definition LOC Anatomical Location Update CDISC Definition A portion of the retina at which the axons of the ganglion cells exit the eyeball to form the optic nerve. No light-sensitive photoreceptors are contained within this portion of the retina. (NCI) The portion of the retina at which the axons of the ganglion cells exit the eyeball to form the optic nerve. 2017-03-31 CDISC-1741 Update C12760 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Optic Papilla - - - 2017-03-31 CDISC-1741 Update C12760 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Second Cranial Nerve - - - 2017-03-31 CDISC-2710 Update C12761 CDISC Definition LOC Anatomical Location Update CDISC Definition The second cranial nerve. (NCI) A cranial nerve extending between the retina and optic chiasma, which innervates the eye. 2017-03-31 CDISC-2710 Update C12761 CDISC Synonym LOC Anatomical Location Add new CDISC Synonym - - - Second Cranial Nerve 2017-03-31 CDISC-2710 Update C12761 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Optic Nerve - - - 2017-03-31 CDISC-1741 Update C12763 CDISC Definition LOC Anatomical Location Update CDISC Definition An air-filled cavity adjacent to the nasal cavity lined by a mucous membrane and located in the bones of the skull. There are four paranasal sinuses on each side of the face: ethmoid, frontal, maxillary, and sphenoid sinus. (NCI) The air-filled cavities adjacent to the nasal cavity lined by a mucous membrane and located in the bones of the skull. 2017-03-31 CDISC-1741 Update C12763 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Accessory Sinuses - - - 2017-03-31 CDISC-1741 Update C12763 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Nasal Cavity - - - 2017-03-31 CDISC-1741 Update C12763 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Nasal Sinuses - - - 2017-03-31 CDISC-1741 Update C12763 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Paranasal Sinus - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12765 CDISC Definition LOC Anatomical Location Update CDISC Definition One of two small paired endocrine glands, superior and inferior, usually found embedded in the connective tissue capsule on the posterior surface of the thyroid gland; these glands secrete parathyroid hormone that regulates the metabolism of calcium and phosphorus. The parenchyma is composed of chief and oxyphilic cells arranged in anastomosing cords. (NCI) Endocrine gland, usually in close proximity to the thyroid gland, that produces parathyroid hormone. 2017-03-31 CDISC-1348 Update C12767 CDISC Definition LOC Anatomical Location Update CDISC Definition The bony, basin-shaped structure formed by the hipbones and the base of the backbone supporting the lower limbs in humans. (NCI) The bony, basin-shaped structure formed by the bones of the pelvis. 2017-03-31 CDISC-1348 Update C12767 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Pelvic Cavity - - - 2017-03-31 CDISC-2710 Update C12768 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Peripheral Nerve - - - 2017-03-31 CDISC-1348 Update C12769 CDISC Definition LOC Anatomical Location Update CDISC Definition The lower part of the abdomen that contains the intestines (the last part of the digestive tract), the stomach, and the liver. It is bound by thin membranes. (NCI) A part of the abdominal cavity that lies between the visceral and parietal peritoneum. 2017-03-31 CDISC-1348 Update C12769 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Peritoneal Cavity - - - 2017-03-31 CDISC-1741 Update C12770 CDISC Definition LOC Anatomical Location Update CDISC Definition The tissue that lines the wall of the abdominal cavity, intestine, and mesentery. It consists of the parietal peritoneum that covers the inside of the abdominal wall and the visceral peritoneum that covers the surface of the intestine and mesentery. (NCI) The membrane that lines the abdominal and pelvic cavities. 2017-03-31 CDISC-1741 Update C12770 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Peritoneum - - - 2017-03-31 CDISC-2710 Update C12774 CDISC Definition LOC Anatomical Location Update CDISC Definition Either one of two arteries arising from the pulmonary trunk that carry deoxygenated blood to the lungs. One of the arteries of the thorax; in general it arises from the pulmonary trunk and branches into the lungs. 2017-03-31 CDISC-2331 Update C12775 CDISC Definition LOC Anatomical Location Update CDISC Definition A valve that is located between and controls the flow of blood from the right ventricle of the heart and the pulmonary artery. (NCI) A cardiac valve located between the right atrium and the pulmonary artery. 2017-03-31 CDISC-1348 Update C12777 CDISC Definition LOC Anatomical Location Update CDISC Definition The long bone that extends from the lateral aspect of the elbow to the medial side of the carpus. The long bone that lies between the radiohumeral joint and the carpus and is adjacent to the ulna. 2017-03-31 CDISC-1348 Update C12777 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Radius - - - 2017-03-31 CDISC-1348 Update C12777 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Radius Bone - - - 2017-03-31 CDISC-2710 Update C12778 CDISC Definition LOC Anatomical Location Update CDISC Definition Either of two arteries (right or left) that arise from the aorta to supply the kidneys. One of the arteries of the abdomen; in general it arises from the abdominal aorta and supplies blood to the kidney. 2017-03-31 CDISC-1348 Update C12783 CDISC Definition LOC Anatomical Location Update CDISC Definition The flat triangle-shaped bone that connects the humerus with the clavicle in the back of the shoulder. (NCI) A bone that articulates with the humerus and is part of the scapulohumeral joint. 2017-03-31 CDISC-1348 Update C12783 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Scapula - - - 2017-03-31 CDISC-1543 Update C12784 CDISC Definition LOC Anatomical Location Update CDISC Definition The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. (From Cline et al., Dictionary of Visual Science, 4th ed) The fibrous, outer tunic of the eyeball that is continuous with the cornea. 2017-03-31 CDISC-1741 Update C12785 CDISC Definition LOC Anatomical Location Update CDISC Definition The musculocutaneous pouch that encloses the testicles. (NCI) The pouch that encloses the testicles. 2017-03-31 CDISC-1741 Update C12785 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Scrotum - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12787 CDISC Definition LOC Anatomical Location Update CDISC Definition One of the two paired glands in the male genitourinary system, posterior to the bladder and superior to the prostate gland, that produces fructose-rich seminal fluid which is a component of semen. These glands join the ipsilateral ductus deferens to form the ejaculatory duct. (NCI) A mammalian male reproductive accessory gland located adjacent to the urinary bladder and proximal to the prostate. 2017-03-31 CDISC-1348 Update C12793 CDISC Definition LOC Anatomical Location Update CDISC Definition The long, flat bone connecting with the cartilages of the first seven ribs and the clavicle. (NCI) The long, flat bone or sternebrae connecting with the cartilage of some ribs. 2017-03-31 CDISC-1348 Update C12793 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Sternum - - - 2017-03-31 CDISC-1348 Update C12796 CDISC Definition LOC Anatomical Location Update CDISC Definition Any one of the seven bones forming the instep of the foot. (NCI) Any of the short bones between the tibiotarsal joint and the tarsometatarsal joint. 2017-03-31 CDISC-1348 Update C12796 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Tarsus - - - 2017-03-31 CDISC-1348 Update C12796 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Tarsus Bone - - - 2017-03-31 CDISC-1348 Update C12800 CDISC Definition LOC Anatomical Location Update CDISC Definition A bone located between the femur and the tarsus, being part of the lower leg. (NCI) The long bone that is medial to the fibula. 2017-03-31 CDISC-1348 Update C12800 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Tibia - - - 2017-03-31 CDISC-2363; CDISC-2331 Update C12802 CDISC Definition LOC Anatomical Location Update CDISC Definition The two organs situated in the throat on either side of the narrow passage from the mouth to the pharynx. They are composed of lymphoid tissues. (NCI) A secondary lymphoid tissue in the mucosa of the pharynx. 2017-03-31 CDISC-2363; CDISC-2331 Update C12802 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Tonsil - - - 2017-03-31 CDISC-2331 Update C12805 CDISC Definition LOC Anatomical Location Update CDISC Definition A three-cusp valve of the heart that regulates the flow of blood between the right atrium and the right ventricle of the heart. (NCI) A cardiac valve located between the right atrium and ventricle. 2017-03-31 CDISC-2331 Update C12805 CDISC Synonym LOC Anatomical Location Add new CDISC Synonym - - - Tricuspid Valve 2017-03-31 CDISC-1741 Update C12806 CDISC Definition LOC Anatomical Location Update CDISC Definition The fifth set of paired nerves of the face that emerge from the brain steam. These nerves have sensory and motor functions in the face, oral cavity, and nasal cavity. (NCI) A cranial nerve extending from the pons, which innervates the skin, mucous membranes, and masticatory muscles of the head. 2017-03-31 CDISC-1741 Update C12806 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Nervus Trigeminus - - - 2017-03-31 CDISC-1741 Update C12806 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Trigeminal Nerve - - - 2017-03-31 CDISC-1348 Update C12809 CDISC Definition LOC Anatomical Location Update CDISC Definition The long bone that extends from the elbow to the lateral side of the carpus. The bone that contains the olecranon process, lies between the radiohumeral joint and the carpus, and is adjacent to the radius. 2017-03-31 CDISC-1348 Update C12809 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Ulna Bone - - - 2017-03-31 CDISC-1741 Update C12812 CDISC Definition LOC Anatomical Location Update CDISC Definition The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx). (MSH2001) A cranial nerve arising from the medulla oblongata, which provides efferent parasympathetic innervation to tissues and viscera in the neck, thorax and abdomen; it also includes somatic and visceral afferent nerve fibers. 2017-03-31 CDISC-1741 Update C12812 CDISC Synonym LOC Anatomical Location Add new CDISC Synonym - - - Tenth Cranial Nerve 2017-03-31 CDISC-2331 Update C12817 CDISC Definition LOC Anatomical Location Update CDISC Definition A large vein which returns blood from the head, neck and extremities to the heart. (NCI) The two major veins (caudal or cranial) that carry deoxygenated blood from the body and drain into the right atrium of the heart. 2017-03-31 CDISC-2331 Update C12817 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Vena Cava - - - 2017-03-31 CDISC-1348 Update C12840 CDISC Definition LOC Anatomical Location Update CDISC Definition The cavity lined by the pleura, located in the thorax and contains heart and lungs. (NCI) A part of the thoracic cavity that lies between the visceral and parietal pleura. 2017-03-31 CDISC-1348 Update C12840 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Pleural Cavity - - - 2017-03-31 CDISC-1348 Update C12843 CDISC Definition LOC Anatomical Location Update CDISC Definition A principal artery that originates in the aorta. It supplies blood to the muscular tissue of the heart. (NCI) One of the arteries of the heart; in general it arises from the aortic root and supplies the myocardium. 2017-03-31 CDISC-1348 Update C12843 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Coronary Artery - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12904 CDISC Definition LOC Anatomical Location Update CDISC Definition One of approximately 20-30 lymph nodes in chain formation that traverse the concavity of the underarm to the clavicle. (NCI) Lymph node(s) in the axillary region. 2017-03-31 CDISC-1670; CDISC-1699 Update C12904 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Axillary Lymph Node - - - 2017-03-31 CDISC-1348 Update C12905 CDISC Definition LOC Anatomical Location Update CDISC Definition The cavity in the vertebrate body enclosed by the ribs between the diaphragm and the neck and containing the lungs and heart. (NCI) The cavity enclosed by the ribs between the diaphragm and the neck. 2017-03-31 CDISC-1348 Update C12905 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Thoracic Cavity - - - 2017-03-31 CDISC-2331 Update C12998 CDISC Definition LOC Anatomical Location Update CDISC Definition A series of bones, muscles, tendons, and other tissues reaching from the base of the skull to the tailbone. The vertebral column forms the axis of the skeleton and encloses as well as protects the spinal cord and the fluid surrounding the spinal cord. (NCI) The series of vertebrae and other tissues extending from the skull to the last tailbone. 2017-03-31 CDISC-2331 Update C12998 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Spinal Column - - - 2017-03-31 CDISC-1741 Update C13005 CDISC Definition LOC Anatomical Location Update CDISC Definition A conical membranous sac filled with serous fluid in which the heart as well as the roots of the aorta and other large blood vessels are contained. (NCI) The membrane surrounding the heart and roots of the vessels at the base of the heart. 2017-03-31 CDISC-1741 Update C13005 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Pericardium - - - 2017-03-31 CDISC-1348 Update C13070 CDISC Definition LOC Anatomical Location Update CDISC Definition The fleshy part of the face bounded by the eyes, nose, ear, and jaw line. (NCI) The soft tissue on the lateral aspects of the face, generally bounded by the eyes, nose, ear, and jaw line. 2017-03-31 CDISC-1543 Update C13071 CDISC Definition LOC Anatomical Location Update CDISC Definition The portion of the head containing the eyes, nose and mouth, cheeks and jaws. The portion of the head that contains the structures such as the eyes, nose, mouth, and jaws. 2017-03-31 CDISC-1543 Update C13071 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Facial - - - 2017-03-31 CDISC-2208 Add C132390 Term LOC Anatomical Location Add new term to existing codelist - - - BRAIN, PERIVENTRICULAR REGION 2017-03-31 CDISC-2330 Add C132391 Term LOC Anatomical Location Add new term to existing codelist - - - DIAPHRAGMATIC LYMPH NODE 2017-03-31 CDISC-2360 Add C132392 Term LOC Anatomical Location Add new term to existing codelist - - - INFERIOR PUBIC RAMUS 2017-03-31 CDISC-2288 Add C132393 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, LEFT, INFERIOR LOBE, ANTERIOR BASAL SEGMENT 2017-03-31 CDISC-2289 Add C132394 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, LEFT, INFERIOR LOBE, LATERAL BASAL SEGMENT 2017-03-31 CDISC-2287 Add C132395 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, LEFT, INFERIOR LOBE, MEDIAL BASAL SEGMENT 2017-03-31 CDISC-2290 Add C132396 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, LEFT, INFERIOR LOBE, POSTERIOR BASAL SEGMENT 2017-03-31 CDISC-2286 Add C132397 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, LEFT, INFERIOR LOBE, SUPERIOR SEGMENT 2017-03-31 CDISC-2283 Add C132398 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, LEFT, SUPERIOR LOBE, ANTERIOR SEGMENT 2017-03-31 CDISC-2282 Add C132399 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, LEFT, SUPERIOR LOBE, APICOPOSTERIOR SEGMENT 2017-03-31 CDISC-2285 Add C132400 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, LEFT, SUPERIOR LOBE, INFERIOR LINGULAR SEGMENT 2017-03-31 CDISC-2284 Add C132401 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, LEFT, SUPERIOR LOBE, SUPERIOR LINGULAR SEGMENT 2017-03-31 CDISC-2279 Add C132402 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, RIGHT, INFERIOR LOBE, ANTERIOR BASAL SEGMENT 2017-03-31 CDISC-2280 Add C132403 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, RIGHT, INFERIOR LOBE, LATERAL BASAL SEGMENT 2017-03-31 CDISC-2278 Add C132404 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, RIGHT, INFERIOR LOBE, MEDIAL BASAL SEGMENT 2017-03-31 CDISC-2281 Add C132405 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, RIGHT, INFERIOR LOBE, POSTERIOR BASAL SEGMENT 2017-03-31 CDISC-2277 Add C132406 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, RIGHT, INFERIOR LOBE, SUPERIOR SEGMENT 2017-03-31 CDISC-2275 Add C132407 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, RIGHT, MIDDLE LOBE, LATERAL SEGMENT 2017-03-31 CDISC-2276 Add C132408 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, RIGHT, MIDDLE LOBE, MEDIAL SEGMENT 2017-03-31 CDISC-2274 Add C132409 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, RIGHT, SUPERIOR LOBE, ANTERIOR SEGMENT 2017-03-31 CDISC-2272 Add C132410 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, RIGHT, SUPERIOR LOBE, APICAL SEGMENT 2017-03-31 CDISC-2273 Add C132411 Term LOC Anatomical Location Add new term to existing codelist - - - LUNG, RIGHT, SUPERIOR LOBE, POSTERIOR SEGMENT 2017-03-31 CDISC-2340 Add C132412 Term LOC Anatomical Location Add new term to existing codelist - - - PERIURETERAL REGION 2017-03-31 CDISC-2247 Add C132413 Term LOC Anatomical Location Add new term to existing codelist - - - PORTAL VEIN BIFURCATION 2017-03-31 CDISC-2323 Add C132414 Term LOC Anatomical Location Add new term to existing codelist - - - PRESACRAL SPACE 2017-03-31 CDISC-2360 Add C132415 Term LOC Anatomical Location Add new term to existing codelist - - - SUPERIOR PUBIC RAMUS 2017-03-31 CDISC-1348 Update C26470 CDISC Definition LOC Anatomical Location Update CDISC Definition The upper jawbone in vertebrates: it is fused to the cranium. (NCI) The upper jaw bone holding the upper teeth. 2017-03-31 CDISC-1348 Update C26470 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Maxilla - - - 2017-03-31 CDISC-1348 Update C28401 CDISC Definition LOC Anatomical Location Update CDISC Definition Anatomical structure located in the vertebral forebrain that receives neural input regarding odors that have been detected by cells within the nasal cavity. The axons of olfactory receptor cells extend into the olfactory bulb. (NCI) The portion of the vertebrate forebrain that lies behind the ethmoid bones; it begins the rhinencephalon. 2017-03-31 CDISC-1348 Update C28401 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Olfactory Bulb - - - 2017-03-31 CDISC-2331 Update C32043 CDISC Definition LOC Anatomical Location Update CDISC Definition The tendon that connects the heel bone to the calf muscles at the back of the lower leg. (NCI) The tendon that, in general, attaches the gastrocnemius muscle to the calcaneous bone in the tarsus. 2017-03-31 CDISC-2331 Update C32043 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Calcaneal Tendon - - - 2017-03-31 CDISC-1348 Update C32200 CDISC Definition LOC Anatomical Location Update CDISC Definition A muscle in the upper limb. Its action involves the rotation of the limb and the flexion of the humeralradial joint. A muscle of the proximal arm/forelimb, in general extending from the scapula to the radius and adjacent fascia; primary function is flexion of the elbow joint and, in some species, also functions in supination of the antebrachium. 2017-03-31 CDISC-1348 Update C32200 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Biceps - - - 2017-03-31 CDISC-2331 Update C32286 CDISC Definition LOC Anatomical Location Update CDISC Definition One of five superficial veins of the upper extremity, beginning at the radial aspect of the wrist area, wrapping around the forearm and emptying into the axillary vein. (NCI) A vein of the arm/forelimb; in general it arises from the dorsal venous network of the hand/forefoot and drains into the axillary vein. 2017-03-31 CDISC-2331 Update C32286 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Cephalic Vein - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C32298 CDISC Definition LOC Anatomical Location Update CDISC Definition Any of the lymph nodes located in the neck. (NCI) Lymph node(s) in the cervical region, or neck. 2017-03-31 CDISC-1670; CDISC-1699 Update C32298 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Cervical Lymph Node - - - 2017-03-31 CDISC-2323 Add C32582 Term LOC Anatomical Location Add new term to existing codelist - - - FALCIFORM LIGAMENT 2017-03-31 CDISC-1543 Update C32622 CDISC Definition LOC Anatomical Location Update CDISC Definition The structure found below the ankle joint required for locomotion. (NCI) The entire structure distal to the ankle joint/tarsus, which includes the metatarsus and digit(s). 2017-03-31 CDISC-1543 Update C32622 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Feet - - - 2017-03-31 CDISC-1543 Update C32622 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Foot - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C32677 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Gingiva - - - 2017-03-31 CDISC-2226 Add C32755 Term LOC Anatomical Location Add new term to existing codelist - - - SUPRAPUBIC REGION 2017-03-31 CDISC-1670; CDISC-1699 Update C32761 CDISC Definition LOC Anatomical Location Update CDISC Definition One of the three lymph nodes of the pelvis: the superior gluteal, interior gluteal or sacral. (NCI) Lymph node(s) adjacent to the iliac vessels in the iliosacral region and cranial to the iliofemoral lymph node. 2017-03-31 CDISC-1670; CDISC-1699 Update C32761 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Iliac Lymph Node - - - 2017-03-31 CDISC-2331 Update C32769 CDISC Definition LOC Anatomical Location Update CDISC Definition One of the teeth in front of the canines in either jaw designed for cutting or gnawing. (NCI) A tooth between the canines in either jaw. 2017-03-31 CDISC-2331 Update C32769 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Incisor - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C32801 CDISC Definition LOC Anatomical Location Update CDISC Definition A superficial or deep lymph node located in the inguinal area. (NCI) Lymph node(s) in the inguinal region. 2017-03-31 CDISC-1670; CDISC-1699 Update C32801 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Inguinal Lymph Node - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C32853 CDISC Definition LOC Anatomical Location Update CDISC Definition Any of the lymph nodes of the breast located under the ribcage, near the sternum. (NCI) Lymph node(s) in or adjacent to the mammary gland. 2017-03-31 CDISC-1670; CDISC-1699 Update C32898 CDISC Definition LOC Anatomical Location Update CDISC Definition A joint connecting the lower part of the femur with the upper part of the tibia. The lower part of the femur and the upper part of the tibia are attached to each other by ligaments. Other structures of the knee joint include the upper part of the fibula, located below and parallel to the tibia, and the patella which moves as the knee bends. (NCI) The joint connecting the lower part of the femur with the upper part of the tibia. 2017-03-31 CDISC-1670; CDISC-1699 Update C32898 CDISC Synonym LOC Anatomical Location Add new CDISC Synonym - - - Femorotibial Joint 2017-03-31 CDISC-1670; CDISC-1699 Update C32898 CDISC Synonym LOC Anatomical Location Add new CDISC Synonym - - - Joint, Stifle 2017-03-31 CDISC-1670; CDISC-1699 Update C33073 CDISC Definition LOC Anatomical Location Update CDISC Definition A lymph node located in the mediastinum. Mediastinal lymph nodes are arranged in three groups, one on the lateral, another on the medial, and a third on the anterior aspect of the vessels; the third group is, however, sometimes absent. (NCI) Lymph node(s) in the mediastinal region. 2017-03-31 CDISC-1670; CDISC-1699 Update C33073 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Mediastinal Lymph Node - - - 2017-03-31 CDISC-1741 Update C33103 CDISC Definition LOC Anatomical Location Update CDISC Definition A double layer of peritoneum that attaches to the back wall of the abdominal cavity and supports the small intestines. (NCI) A double layer of peritoneum that attaches to the wall of the abdominal cavity and supports the small intestines. 2017-03-31 CDISC-2732 Add C33191 Term LOC Anatomical Location Add new term to existing codelist - - - OBTURATOR EXTERNUS MUSCLE 2017-03-31 CDISC-2732 Add C33192 Term LOC Anatomical Location Add new term to existing codelist - - - OBTURATOR INTERNUS MUSCLE 2017-03-31 CDISC-2323 Add C33193 Term LOC Anatomical Location Add new term to existing codelist - - - OBTURATOR MUSCLE 2017-03-31 CDISC-1741 Update C33205 CDISC Definition LOC Anatomical Location Update CDISC Definition The part of the nasal mucosa composed of neuroepithelial tissue and mucus-producing Bowman's glands. The mucus moistens the epithelium and helps dissolve odor-containing gases. (NCI) The mucosal membranes that line the nasal cavity. 2017-03-31 CDISC-1741 Update C33205 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Olfactory Mucosa - - - 2017-03-31 CDISC-1741 Update C33209 CDISC Definition LOC Anatomical Location Update CDISC Definition A fold of peritoneum originating at the stomach and supporting the viscera. (NCI) A double layer of peritoneum covering abdominal organs. 2017-03-31 CDISC-1741 Update C33209 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Omental Fat - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C33278 CDISC Definition LOC Anatomical Location Update CDISC Definition A lymph node located close to, on, or within the parotid gland. (NCI) Lymph node(s) in or adjacent to the parotid gland. 2017-03-31 CDISC-1348 Update C33282 CDISC Definition LOC Anatomical Location Update CDISC Definition A small flat triangular bone in front of the knee that articulates with the femur and protects the knee joint. (NCI) A small bone in front of the femorotibial joint that articulates with the femur. 2017-03-31 CDISC-1348 Update C33282 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Patella - - - 2017-03-31 CDISC-1348 Update C33287 CDISC Definition LOC Anatomical Location Update CDISC Definition The caudal portion of the trunk, bounded anteriorly and laterally by the two hip bones incorporating the socket portion of the hip joint for each leg. Posteriorly it is bounded by the sacrum and coccyx. (NCI) The bony structure composed of the ilium, ishium, pubis and sacrum, which are typically fused during maturation. 2017-03-31 CDISC-1348 Update C33287 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Pelvis Bone - - - 2017-03-31 CDISC-2331 Update C33318 CDISC Definition LOC Anatomical Location Update CDISC Definition A fold of lymphatic tissue covered by ciliated epithelium at the very back of the nose, in the roof of the nasopharynx. (NCI) A tonsil in the mucosa of the nasopharynx. 2017-03-31 CDISC-2331 Update C33318 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Pharyngeal Tonsil - - - 2017-03-31 CDISC-2331 Update C33343 CDISC Definition LOC Anatomical Location Update CDISC Definition A short thick trunk vein that transports blood containing the absorbed products of digestion from the intestine directly to the liver. (NCI) A vein lying in the lower part of the abdomen; in general it arises from the junction of the mesenteric and splenic veins and draining into the liver. 2017-03-31 CDISC-2331 Update C33343 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Portal Vein - - - 2017-03-31 CDISC-1741 Update C33441 CDISC Definition LOC Anatomical Location Update CDISC Definition A group of four powerful muscles in the front of the thigh. Their actions involve the extension of the knee joint. (NCI) A group of muscles in the thigh, in general extending from the pelvis to the patella and tibia; primary function is extension of the femorotibial joint. 2017-03-31 CDISC-1741 Update C33441 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Muscle, Quadriceps - - - 2017-03-31 CDISC-1741 Update C33441 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Muscle, Thigh - - - 2017-03-31 CDISC-2331 Update C33511 CDISC Definition LOC Anatomical Location Update CDISC Definition One of two (Greater, Small) superficial veins of the leg and thigh. (NCI) A vein of the leg/hindlimb; in general it arises from the venous network of the leg/hindfoot and drains into the femoral vein. 2017-03-31 CDISC-1670; CDISC-1699 Update C33519 CDISC Definition LOC Anatomical Location Update CDISC Definition Small glands located within the epidermis, and associated with the hair follicle, that produce and secrete an oily substance that lubricates the skin and hair. (NCI) Small glands located within the skin that are usually associated with the hair follicle. 2017-03-31 CDISC-2331 Update C33645 CDISC Definition LOC Anatomical Location Update CDISC Definition Adipose tissue located under the dermis. It binds underlying structures with the skin. The subcutis is important in the regulation of temperature of the skin itself and the body. The size of this layer varies throughout the body and from subject to subject. Adipose and connective tissue located deep to the dermis. 2017-03-31 CDISC-2331 Update C33645 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Subcutaneous Adipose Tissue - - - 2017-03-31 CDISC-1543 Update C33718 CDISC Definition LOC Anatomical Location Update CDISC Definition A viscid fluid secreted by the synovial membrane, serving as a lubricant. (NCI) The fluid within a joint capsule. 2017-03-31 CDISC-1543 Update C33718 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Synovial Fluid - - - 2017-03-31 CDISC-1348 Update C38662 CDISC Definition LOC Anatomical Location Update CDISC Definition The potential body space formed between the parietal and visceral layers of the pericardial sac. (NCI) The body space between the epicardium and the pericardium. 2017-03-31 CDISC-1348 Update C38662 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Pericardial Cavity - - - 2017-03-31 CDISC-2340 Add C41449 Term LOC Anatomical Location Add new term to existing codelist - - - EPIDURAL SPACE 2017-03-31 CDISC-1670; CDISC-1699 Update C43362 CDISC Definition LOC Anatomical Location Update CDISC Definition The lower opening of the digestive tract, lying in the cleft between the buttocks, through which fecal matter is extruded. (NCI) The distal orifice of the digestive tract located between the rectum and the external surface of the body, comprising glandular, transitional, and squamous epithelium. 2017-03-31 CDISC-1670; CDISC-1699 Update C43362 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Anus - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C49018 CDISC Definition LOC Anatomical Location Update CDISC Definition A lymph node that drains lymph from a region of interest. (NCI) Lymph node(s) that drains the lymph from a region of interest. 2017-03-31 CDISC-1670; CDISC-1699 Update C49018 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Regional Lymph Node - - - 2017-03-31 CDISC-1741 Update C52810 CDISC Definition LOC Anatomical Location Update CDISC Definition The longest single nerve that is formed by the merging of the ventral rami of the L4, L5, and S1 in the pelvis and passes down the lower limb where it divides into the common peroneal and tibial nerves. (NCI) A nerve arising from the merge of the lumbar and sacral rami in the pelvis and dividing into the common peroneal and tibial nerves, and which innervates the muscles of the thigh. 2017-03-31 CDISC-1741 Update C52810 CDISC Synonym LOC Anatomical Location Remove CDISC Synonym Sciatic Nerve - - - 2017-03-31 CDISC-1348 Update C52941 CDISC Definition LOC Anatomical Location Update CDISC Definition The blood vessel that supplies the breast and the anterior chest wall with arterial blood. It is located in the chest wall. (NCI) An artery of the thoracic wall; in general it arises from the subclavian artery and branches into the musculophrenic and superior epigastric arteries. 2017-03-31 CDISC-2710 Update C52975 CDISC Definition LOC Anatomical Location Update CDISC Definition A branch of the abdominal aorta that supplies blood to the intestines. (NCI) One of the arteries of the abdomen; in general it arises from the abdominal aorta and supplies blood mainly to the intestines. 2017-03-31 CDISC-2710 Update C53073 CDISC Definition LOC Anatomical Location Update CDISC Definition The largest muscle of the quadriceps femoris muscle group that extends laterally from the intertrochanteric line of the femur to the lateral aspects of the quadriceps femoris tendon and patella. A muscle in the quadriceps femoris muscle group lateral to the vastus intermedius; primary function is the extension of the femorotibial joint. 2017-03-31 CDISC-1670; CDISC-1699 Update C53146 CDISC Definition LOC Anatomical Location Update CDISC Definition Lymph node located within the fat layer of the knee joint. (NCI) Lymph node(s) adjacent to the femorotibial joint. 2017-03-31 CDISC-1348 Update C53147 CDISC Definition LOC Anatomical Location Update CDISC Definition A muscle in the back of the thigh. Its action involves the knee flexion and hip extension. (NCI) A muscle in the thigh, in general extending from the ischial tuberosity and posterior femur to the fibula; primary function is to extend the femorotibial joint. 2017-03-31 CDISC-1741 Update C53175 CDISC Definition LOC Anatomical Location Update CDISC Definition One of the four quadriceps muscles, located in the middle of the front of the thigh. Its actions involve the extension of the knee joint and flexion of the hip. (NCI) A muscle in the quadriceps femoris muscle group between the vastus lateralis and vastus medialis and lying on the vastus intermedius; primary function is extension of the femorotibilal joint. 2017-03-31 CDISC-1741 Update C53176 CDISC Definition LOC Anatomical Location Update CDISC Definition A muscle located at the posterior and medial aspect of the thigh that extends the hip joint, flexes the knee joint and assists in medially rotating the knee. A muscle of the thigh, in general extends from the ishium to the medial tibia; primary function is the extension of the hip. 2017-03-31 CDISC-1348 Update C77608 CDISC Definition LOC Anatomical Location Update CDISC Definition The tissues that surround the organs that are present within the abdominal cavity. The abdominal wall tissue is composed of layers of fat, parietal peritoneum, fascia, and muscles. (NCI) The tissue that surrounds the organs present in the abdominal cavity. 2017-03-31 CDISC-1741 Update C77637 CDISC Definition LOC Anatomical Location Update CDISC Definition Moist tissue lining the oral cavity, containing mucus secreting glands. The mucosal membranes that line the oral cavity. 2017-03-31 CDISC-1670; CDISC-1699 Update C77640 CDISC Definition LOC Anatomical Location Update CDISC Definition Any of the lymph nodes adjacent to the stomach and duodenum. (NCI) Lymph node(s) adjacent to the liver. 2017-03-31 CDISC-1670; CDISC-1699 Update C77641 CDISC Definition LOC Anatomical Location Update CDISC Definition A lymph node located in the mesentery. (NCI) Lymph node(s) in or adjacent to the mesentery. 2017-03-31 CDISC-1670; CDISC-1699 Update C77642 CDISC Definition LOC Anatomical Location Update CDISC Definition A lymph node of the pancreas. (NCI) Lymph node(s) in or adjacent to the pancreas. 2017-03-31 CDISC-1670; CDISC-1699 Update C77643 CDISC Definition LOC Anatomical Location Update CDISC Definition A lymph node located adjacent to the lumbar region of the spine. (NCI) Lymph node(s) adjacent to the lumbar vertebral column. 2017-03-31 CDISC-1670; CDISC-1699 Update C77645 CDISC Definition LOC Anatomical Location Update CDISC Definition Lymph nodes surrounding the portal vein. (NCI) Lymph node(s) adjacent to the portal vein. 2017-03-31 CDISC-1670; CDISC-1699 Update C77650 CDISC Definition LOC Anatomical Location Update CDISC Definition A lymph node located beneath the floor of the oral cavity. (NCI) Lymph node(s) adjacent to the mandible. 2017-03-31 CDISC-1670; CDISC-1699 Update C79432 CDISC Definition LOC Anatomical Location Update CDISC Definition Exocrine glands located at the anterior aspect of the genitals of some mammals, such as mice and rats, that produce and secrete pheromones. (NCI) Exocrine glands of the male reproductive system located adjacent to the prepuce. 2017-03-31 CDISC-2323 Add C89787 Term LOC Anatomical Location Add new term to existing codelist - - - PARACOLIC GUTTER 2017-03-31 CDISC-1670; CDISC-1699 Update C92221 CDISC Definition LOC Anatomical Location Update CDISC Definition An axillary lymph node along the brachial vein. (NCI) Lymph node(s) adjacent to the brachial vein. 2017-03-31 CDISC-2710 Remove C106539 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Lipocalin-2 - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C111124 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Abnormal Cells - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C112274 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Estrogen Receptor - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C112312 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Human Epidermal Growth Factor Receptor 2 - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C117846 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Progesterone Receptor - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C122102 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Beta-defensin 2 - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C123555 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Breast Cancer Type 1 Susceptibility Prot - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C123556 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Cancer Cellularity - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C123557 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Ki-67 - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C123558 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist NK2 Homeobox 1 - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C123559 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Percentage of In situ Carcinoma - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C123560 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Surgical Margins Status - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127763 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Cytokeratin 16 - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127764 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Dendritic Cell-Lysosomal-Assoc Memb Prot - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127765 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Fibrosis - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127766 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Lymphatic Invasion - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127767 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Normal Cells/Total Cells - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127768 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Perineural Invasion - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127769 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist S100 Calcium Binding Protein A7 - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127770 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Stromal Cells/Total Cells - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127771 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Tumor Cells/Total Cells - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127772 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Vascular Invasion - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C41145 Term MITEST Microscopic Findings Test Name Remove term entirely from codelist Thickness - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Update C89973 CDISC Codelist Name MITEST SEND Microscopic Findings Test Name Update CDISC Codelist Name Microscopic Findings Test Name SEND Microscopic Findings Test Name 2017-03-31 CDISC-2710 Update C89973 CDISC Definition MITEST SEND Microscopic Findings Test Name Update CDISC Definition Terminology for the test names concerned with the findings from a specimen that are visible by microscopic analysis. Terminology for the test codes concerned with the non-clinical findings from a specimen that are visible by microscopic analysis. 2017-03-31 CDISC-2710 Update C89973 CDISC Synonym MITEST SEND Microscopic Findings Test Name Add new CDISC Synonym - - - SEND Microscopic Findings Test Name 2017-03-31 CDISC-2710 Update C89973 CDISC Synonym MITEST SEND Microscopic Findings Test Name Remove CDISC Synonym Microscopic Findings Test Name - - - 2017-03-31 CDISC-2710 Update C90424 CDISC Codelist Name MITEST SEND Microscopic Findings Test Name Update CDISC Codelist Name Microscopic Findings Test Name SEND Microscopic Findings Test Name 2017-03-31 CDISC-2710 Remove C106539 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist LCN2 - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C111124 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist ABNCE - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C112274 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist ESTRCPT - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C112312 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist HER2 - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C117846 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist PROGESTR - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C122102 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist BD2 - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C123555 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist BRCA1 - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C123556 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist CANCLLTY - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C123557 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist KI67 - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C123558 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist NKX2_1 - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C123559 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist PCTISCA - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C123560 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist SGMGSTAT - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127763 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist CY16 - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127764 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist DCLAMP - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127765 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist FIBROSIS - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127766 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist LYMPHINV - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127767 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist NORMCECE - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127768 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist PNLINV - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127769 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist S100A7 - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127770 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist STRMCECE - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127771 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist TUMCECE - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C127772 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist VASINV - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Remove C41145 Term MITESTCD Microscopic Findings Test Code Remove term entirely from codelist THICK - - - SEND IG 3.0 and 3.1 only support the use of a single test, Microscopic Examination, within this codelist. The SEND team will consider adding new terms in future. 2017-03-31 CDISC-2710 Update C89974 CDISC Codelist Name MITESTCD SEND Microscopic Findings Test Code Update CDISC Codelist Name Microscopic Findings Test Code SEND Microscopic Findings Test Code 2017-03-31 CDISC-2710 Update C89974 CDISC Definition MITESTCD SEND Microscopic Findings Test Code Update CDISC Definition Terminology for the test codes concerned with the findings from a specimen that are visible by microscopic analysis. Terminology for the test codes concerned with the non-clinical findings from a specimen that are visible by microscopic analysis. 2017-03-31 CDISC-2710 Update C89974 CDISC Synonym MITESTCD SEND Microscopic Findings Test Code Add new CDISC Synonym - - - SEND Microscopic Findings Test Code 2017-03-31 CDISC-2710 Update C89974 CDISC Synonym MITESTCD SEND Microscopic Findings Test Code Remove CDISC Synonym Microscopic Findings Test Code - - - 2017-03-31 CDISC-2710 Update C90424 CDISC Codelist Name MITESTCD SEND Microscopic Findings Test Code Update CDISC Codelist Name Microscopic Findings Test Code SEND Microscopic Findings Test Code 2017-03-31 CDISC-2633 Add C27134 Term NEOPLASM Neoplasm Type Add new term to existing codelist - - - HEMOLYMPHORETICULAR TUMOR, MALIGNANT 2017-03-31 CDISC-2669 Add C113484 Term NONNEO Non-Neoplastic Finding Type Add new term to existing codelist - - - INTUSSUSCEPTION 2017-03-31 CDISC-2669 Add C132483 Term NONNEO Non-Neoplastic Finding Type Add new term to existing codelist - - - ACCUMULATION, ADIPOCYTES 2017-03-31 CDISC-2710 Add C132484 Term NONNEO Non-Neoplastic Finding Type Add new term to existing codelist - - - ANGIECTASIS 2017-03-31 CDISC-2669 Add C132485 Term NONNEO Non-Neoplastic Finding Type Add new term to existing codelist - - - APOPTOSIS/NECROSIS 2017-03-31 CDISC-2669 Add C132486 Term NONNEO Non-Neoplastic Finding Type Add new term to existing codelist - - - ECTOPIC TISSUE 2017-03-31 CDISC-2669 Add C132487 Term NONNEO Non-Neoplastic Finding Type Add new term to existing codelist - - - EOSINOPHILIC GLOBULES 2017-03-31 CDISC-2669 Add C132488 Term NONNEO Non-Neoplastic Finding Type Add new term to existing codelist - - - HELICOBACTER 2017-03-31 CDISC-2600; CDISC-2669 Add C17557 Term NONNEO Non-Neoplastic Finding Type Add new term to existing codelist - - - APOPTOSIS 2017-03-31 CDISC-2669 Add C97087 Term NONNEO Non-Neoplastic Finding Type Add new term to existing codelist - - - LYMPHANGIECTASIS 2017-03-31 CDISC-2407 Add C132321 CDISC Codelist NORMRS Within Normal Limits Results Addition of new codelist - - - NORMRS 2017-03-31 CDISC-2407 Add C14165 Term NORMRS Within Normal Limits Results Add new term to new codelist - - - NORMAL 2017-03-31 CDISC-2407 Add C96301 Term NORMRS Within Normal Limits Results Add new term to new codelist - - - UNREMARKABLE 2017-03-31 CDISC-2663 Add C132302 Term PKPARM PK Parameters Add new term to existing codelist - - - Average Conc from T1 to T2 2017-03-31 CDISC-2614 Add C132435 Term PKPARM PK Parameters Add new term to existing codelist - - - Accum Ratio AUCTAU norm by dose 2017-03-31 CDISC-2614 Add C132436 Term PKPARM PK Parameters Add new term to existing codelist - - - Accum Ratio AUC T1 to T2 norm by dose 2017-03-31 CDISC-2614 Add C132437 Term PKPARM PK Parameters Add new term to existing codelist - - - Accum Ratio Cmax norm by dose 2017-03-31 CDISC-2614 Add C132438 Term PKPARM PK Parameters Add new term to existing codelist - - - Accum Ratio Cmin norm by dose 2017-03-31 CDISC-2614 Add C132439 Term PKPARM PK Parameters Add new term to existing codelist - - - Accum Ratio Ctrough norm by dose 2017-03-31 CDISC-2732 Add C132440 Term PKPARM PK Parameters Add new term to existing codelist - - - Average Conc from T1 to T2 Norm by BMI 2017-03-31 CDISC-2663 Add C132441 Term PKPARM PK Parameters Add new term to existing codelist - - - Average Conc from T1 to T2 Norm by Dose 2017-03-31 CDISC-2663 Add C132442 Term PKPARM PK Parameters Add new term to existing codelist - - - Average Conc from T1 to T2 Norm by SA 2017-03-31 CDISC-2663 Add C132443 Term PKPARM PK Parameters Add new term to existing codelist - - - Average Conc from T1 to T2 Norm by WT 2017-03-31 CDISC-2663 Add C132302 Term PKPARMCD PK Parameters Code Add new term to existing codelist - - - CAVGINT 2017-03-31 CDISC-2614 Add C132435 Term PKPARMCD PK Parameters Code Add new term to existing codelist - - - ARAUCD 2017-03-31 CDISC-2614 Add C132436 Term PKPARMCD PK Parameters Code Add new term to existing codelist - - - ARAUCIND 2017-03-31 CDISC-2614 Add C132437 Term PKPARMCD PK Parameters Code Add new term to existing codelist - - - ARCMAXD 2017-03-31 CDISC-2614 Add C132438 Term PKPARMCD PK Parameters Code Add new term to existing codelist - - - ARCMIND 2017-03-31 CDISC-2614 Add C132439 Term PKPARMCD PK Parameters Code Add new term to existing codelist - - - ARCTROUD 2017-03-31 CDISC-2732 Add C132440 Term PKPARMCD PK Parameters Code Add new term to existing codelist - - - CAVGINTB 2017-03-31 CDISC-2663 Add C132441 Term PKPARMCD PK Parameters Code Add new term to existing codelist - - - CAVGINTD 2017-03-31 CDISC-2663 Add C132442 Term PKPARMCD PK Parameters Code Add new term to existing codelist - - - CAVGINTS 2017-03-31 CDISC-2663 Add C132443 Term PKPARMCD PK Parameters Code Add new term to existing codelist - - - CAVGINTW 2017-03-31 CDISC-2444 Add C106531 Term PKUDMG PK Units of Measure - Dose mg Add new term to existing codelist - - - h*mmol/L/mg 2017-03-31 CDISC-2453 Add C112247 Term PKUDMG PK Units of Measure - Dose mg Add new term to existing codelist - - - day*ug/mL/mg 2017-03-31 "CDISC-2574: CDISC-2610" Add C112307 Term PKUDMG PK Units of Measure - Dose mg Add new term to existing codelist - - - h*nmol/L/mg 2017-03-31 CDISC-2523 Add C132444 Term PKUDMG PK Units of Measure - Dose mg Add new term to existing codelist - - - day*ug/mL/(mg/kg) 2017-03-31 CDISC-2614 Add C132445 Term PKUDMG PK Units of Measure - Dose mg Add new term to existing codelist - - - h*nmol/L/(mg/kg) 2017-03-31 CDISC-2603; CDISC-2658 Add C132446 Term PKUDMG PK Units of Measure - Dose mg Add new term to existing codelist - - - h*umol/L/(mg/kg) 2017-03-31 CDISC-2732 Add C106531 Term PKUDUG PK Units of Measure - Dose ug Add new term to existing codelist - - - h*umol/L/ug 2017-03-31 CDISC-2732 Add C112247 Term PKUDUG PK Units of Measure - Dose ug Add new term to existing codelist - - - day*ng/mL/ug 2017-03-31 CDISC-2611 Add C112307 Term PKUDUG PK Units of Measure - Dose ug Add new term to existing codelist - - - h*pmol/L/ug 2017-03-31 CDISC-2614 Add C65045 Term PKUNIT PK Units of Measure Add new term to existing codelist - - - pmol 2017-03-31 CDISC-2444 Update C106531 CDISC Definition PKUWG PK Units of Measure - Weight g Update CDISC Definition Hours times moles per liter (area under the curve), divided by grams (weight). Hours times millimoles per liter (area under the curve), divided by kilograms (weight); or hours times micromoles per liter (area under the curve), divided by grams (weight); or hours times nanomoles per liter (area under the curve), divided by milligrams (dose); or hours times picomoles per liter (area under the curve), divided by micrograms (dose). 2017-03-31 CDISC-2444 Update C106531 CDISC Synonym PKUWG PK Units of Measure - Weight g Add new CDISC Synonym - - - h*mmol/L/mg 2017-03-31 CDISC-2444 Update C106531 CDISC Synonym PKUWG PK Units of Measure - Weight g Add new CDISC Synonym - - - h*mol/L/g 2017-03-31 CDISC-2444 Update C106531 CDISC Synonym PKUWG PK Units of Measure - Weight g Add new CDISC Synonym - - - h*umol/L/ug 2017-03-31 CDISC-2453 Update C112247 CDISC Definition PKUWG PK Units of Measure - Weight g Update CDISC Definition Days times grams per milliliter (area under the curve), divided by kilograms (weight) or days times milligrams per milliliter (area under the curve), divided by grams (weight). Days times grams per milliliter (area under the curve), divided by kilograms (weight); or days times milligrams per milliliter (area under the curve), divided by grams (weight); or days times micrograms per milliliter (area under the curve), divided by milligrams (dose); or days times nanograms per milliliter (area under the curve), divided by micrograms (dose). 2017-03-31 CDISC-2453 Update C112247 CDISC Synonym PKUWG PK Units of Measure - Weight g Add new CDISC Synonym - - - day*ng/mL/ug 2017-03-31 CDISC-2453 Update C112247 CDISC Synonym PKUWG PK Units of Measure - Weight g Add new CDISC Synonym - - - day*ug/mL/mg 2017-03-31 "CDISC-2574: CDISC-2610" Update C112307 CDISC Definition PKUWG PK Units of Measure - Weight g Update CDISC Definition Hours times millimoles per liter (area under the curve), divided by kilograms (weight) or hours times micromoles per liter (area under the curve), divided by grams (weight). Hours times millimoles per liter (area under the curve), divided by kilograms (weight); or hours times micromoles per liter (area under the curve), divided by grams (weight); or hours times nanomoles per liter (area under the curve), divided by milligrams (dose); or hours times picomoles per liter (area under the curve), divided by micrograms (dose). 2017-03-31 "CDISC-2574: CDISC-2610" Update C112307 CDISC Synonym PKUWG PK Units of Measure - Weight g Add new CDISC Synonym - - - h*nmol/L/mg 2017-03-31 "CDISC-2574: CDISC-2610" Update C112307 CDISC Synonym PKUWG PK Units of Measure - Weight g Add new CDISC Synonym - - - h*pmol/L/ug 2017-03-31 CDISC-2453 Update C112247 CDISC Definition PKUWKG PK Units of Measure - Weight kg Update CDISC Definition Days times grams per milliliter (area under the curve), divided by kilograms (weight) or days times milligrams per milliliter (area under the curve), divided by grams (weight). Days times grams per milliliter (area under the curve), divided by kilograms (weight); or days times milligrams per milliliter (area under the curve), divided by grams (weight); or days times micrograms per milliliter (area under the curve), divided by milligrams (dose); or days times nanograms per milliliter (area under the curve), divided by micrograms (dose). 2017-03-31 CDISC-2453 Update C112247 CDISC Synonym PKUWKG PK Units of Measure - Weight kg Add new CDISC Synonym - - - day*ng/mL/ug 2017-03-31 CDISC-2453 Update C112247 CDISC Synonym PKUWKG PK Units of Measure - Weight kg Add new CDISC Synonym - - - day*ug/mL/mg 2017-03-31 CDISC-2611 Update C112307 CDISC Definition PKUWKG PK Units of Measure - Weight kg Update CDISC Definition Hours times millimoles per liter (area under the curve), divided by kilograms (weight) or hours times micromoles per liter (area under the curve), divided by grams (weight). Hours times millimoles per liter (area under the curve), divided by kilograms (weight); or hours times micromoles per liter (area under the curve), divided by grams (weight); or hours times nanomoles per liter (area under the curve), divided by milligrams (dose); or hours times picomoles per liter (area under the curve), divided by micrograms (dose). 2017-03-31 CDISC-2611 Update C112307 CDISC Synonym PKUWKG PK Units of Measure - Weight kg Add new CDISC Synonym - - - h*nmol/L/mg 2017-03-31 CDISC-2611 Update C112307 CDISC Synonym PKUWKG PK Units of Measure - Weight kg Add new CDISC Synonym - - - h*pmol/L/ug 2017-03-31 CDISC-1348 Update C111141 CDISC Definition SPEC Specimen Update CDISC Definition An epithelial outgrowth of lymphoid tissue in the cloaca of young birds, responsible for B-lymphocyte maturation. It undergoes atrophy and involution at six months of age. A region of the cloaca in avian species responsible for B-cell maturation. 2017-03-31 CDISC-1348 Update C111156 CDISC Definition SPEC Specimen Update CDISC Definition An evagination of the oral mucosa within the cheek of some mammals, which forms a pocket. (NCI) An invagination of the oral mucosa within the cheek of some mammals that forms a pocket. 2017-03-31 CDISC-1543 Update C111162 CDISC Definition SPEC Specimen Update CDISC Definition A saccular diverticulum of the esophagus in bird species that is used for food storage prior to digestion. A saccular expansion of the esophagus in most avian species that can be used for food storage. 2017-03-31 CDISC-2710 Update C111301 CDISC Definition SPEC Specimen Update CDISC Definition A portion of the digestive system of birds, insects and invertebrates lying between the crop and the ventriculus. It is responsible for the secretion of gastric enzymes and moving food into the ventriculus. The portion of the stomach of some non-mammalian species located between the thoracic esophagus and the ventriculus. 2017-03-31 CDISC-1670; CDISC-1699 Update C111308 CDISC Definition SPEC Specimen Update CDISC Definition The synovial ball and socket joint involving the articulation of the glenoid fossa of the scapula and the head of the humerus. (NCI) The joint connecting the scapula and the proximal portion of the humerus. 2017-03-31 CDISC-2331 Update C111323 CDISC Definition SPEC Specimen Update CDISC Definition The vocal organ of a bird that is located in the lower portion of the larynx. (NCI) The vocal organ of a bird located near the tracheal bifurcation. 2017-03-31 CDISC-2710 Update C112234 CDISC Definition SPEC Specimen Update CDISC Definition A superficial muscle located on the midline of the perineum. It covers the bulb of the penis in males and the vestibular bulb in females. Paired superficial muscles on the midline of the perineum, covering the bulb of the penis in males and the vestibular bulb in females. 2017-03-31 CDISC-2331 Update C112425 CDISC Definition SPEC Specimen Update CDISC Definition Bone structure covering the ventral aspect of the middle ear. The bony structure containing an inner lumen within the middle ear. 2017-03-31 CDISC-2363 Update C112430 CDISC Definition SPEC Specimen Update CDISC Definition A tissue sample that contains the bulbocavernosus and the levator ani. A specimen that contains the bulbospongiosus and levator ani muscles. 2017-03-31 CDISC-2331 Update C114236 CDISC Definition SPEC Specimen Update CDISC Definition A pouch below the proventriculus in some birds, insects, reptiles and invertebrates. It is responsible for digestion. The portion of the stomach of some non-mammalian species located between the proventriculus and the small intestine. 2017-03-31 CDISC-2710 Update C117736 CDISC Definition SPEC Specimen Update CDISC Definition The portion of the quadriceps femoris muscle group that extends medially from the intertrochanteric line of the femur to the medial aspects of the quadriceps femoris tendon and patella. (NCI) A muscle in the quadriceps femoris muscle group medial to the vastus intermedius; primary function is the extension of the femorotibial joint. 2017-03-31 CDISC-2710 Update C117876 CDISC Definition SPEC Specimen Update CDISC Definition The portion of the quadriceps femoris muscle group that is underneath the Rectus Femoris muscle, spans and covers the upper two-thirds of the anterior and lateral surfaces of the femur, and inserts into the lateral border of the patella. A muscle in the quadriceps femoris muscle group between the vastus lateralis and vastus medialis deep to the rectus femoris; primary function is the extension of the femorotibial joint. 2017-03-31 CDISC-2363 Update C117978 CDISC Definition SPEC Specimen Update CDISC Definition A laboratory specimen consisting of either preputial or clitoral gland. A specimen that contains either the preputial or clitoral glands. 2017-03-31 CDISC-2710 Update C117979 CDISC Definition SPEC Specimen Update CDISC Definition One of three superficial muscles in primates between the soleus and the gastrocnemius, and assists in flexing the foot and knee. A superficial muscle in primates between the soleus and the gastrocnemius; primary function is flexion of the tarsus and femorotibial joint. 2017-03-31 CDISC-2710 Update C117980 CDISC Definition SPEC Specimen Update CDISC Definition A long muscle of the neck that extends from the manubrium sterni to the mandible and branches at the middle of the neck, forming the ventral border of the jugular groove. A muscle of the neck extending from the manubrium sterni to the head; primary function is lateral movement of the head and neck. 2017-03-31 CDISC-1741 Update C12230 CDISC Definition SPEC Specimen Update CDISC Definition The bony anterior part of the roof of the mouth separating the nose from the mouth. (NCI) The part of the roof of the mouth supported by bone. 2017-03-31 CDISC-1741 Update C12230 CDISC Synonym SPEC Specimen Remove CDISC Synonym Hard Palate - - - 2017-03-31 CDISC-1741 Update C12231 CDISC Definition SPEC Specimen Update CDISC Definition A movable fold suspended from the posterior border of the hard palate. (MeSH) The part of the roof of the mouth not supported by bone. 2017-03-31 CDISC-1670; CDISC-1699 Update C12233 CDISC Definition SPEC Specimen Update CDISC Definition One of two salivary glands in the neck, located in the space bound by the two bellies of the digastric muscle and the angle of the mandible. It discharges through the submandibular duct. (MeSH) (NCI) The salivary gland located adjacent to the mandible. 2017-03-31 CDISC-1670; CDISC-1699 Update C12234 CDISC Definition SPEC Specimen Update CDISC Definition A salivary gland located under the tongue in the floor of the oral cavity. (NCI) The salivary gland located under the tongue in the floor of the oral cavity or adjacent to the submandibular salivary gland. 2017-03-31 CDISC-2331 Update C12256 CDISC Definition SPEC Specimen Update CDISC Definition The area around the esophagogastric mucosal junction where the esophageal mucosa transitions into the gastric mucosa. (NCI) The region of the stomach adjacent to the esophogastric junction. 2017-03-31 CDISC-2331 Update C12256 CDISC Synonym SPEC Specimen Remove CDISC Synonym Gastric Cardia - - - 2017-03-31 CDISC-2331 Update C12257 CDISC Definition SPEC Specimen Update CDISC Definition The portion of the stomach that lies above the cardiac notch. It allows for the accumulation of gases produced by chemical digestion. (NCI) The blind sac region of the glandular stomach. 2017-03-31 CDISC-2331 Update C12257 CDISC Synonym SPEC Specimen Remove CDISC Synonym Fundus of the Stomach - - - 2017-03-31 CDISC-2331 Update C12260 CDISC Definition SPEC Specimen Update CDISC Definition The lower part of the stomach that connects to the duodenum. (NCI) The region of the stomach that connects to the duodenum. 2017-03-31 CDISC-2331 Update C12263 CDISC Definition SPEC Specimen Update CDISC Definition A jointed tube 25-30 cm long that connects the stomach to the jejunum. (NCI) The portion of the small intestine between the stomach and jejunum. 2017-03-31 CDISC-2710 Update C12272 CDISC Definition SPEC Specimen Update CDISC Definition A duct extending from the pancreas to supply pancreatic content to the duodenum. A duct that conveys pancreatic secretions from the pancreas to the duodenum. 2017-03-31 CDISC-1741 Update C12274 CDISC Definition SPEC Specimen Update CDISC Definition The part of the ear including the eardrum and ossicles. The middle ear leads to the inner ear. (NCI) The part of the ear including the eardrum and ossicles. 2017-03-31 CDISC-1741 Update C12274 CDISC Synonym SPEC Specimen Remove CDISC Synonym Middle Ear - - - 2017-03-31 CDISC-1741 Update C12298 CDISC Definition SPEC Specimen Update CDISC Definition The back of the abdomen where the kidneys lie and the great blood vessels run. (NCI) The region of the abdomen outside the peritoneum, where the kidneys lie and the great blood vessels run. 2017-03-31 CDISC-1741 Update C12298 CDISC Synonym SPEC Specimen Remove CDISC Synonym RETROPERITONEAL CAVITY - - - 2017-03-31 CDISC-1741 Update C12299 CDISC Definition SPEC Specimen Update CDISC Definition The pigmented protuberance on the surface of the breast through which milk is drawn from the breast. (NCI) The protuberance in the skin where the ducts of the mammary gland open. 2017-03-31 CDISC-1741 Update C12299 CDISC Synonym SPEC Specimen Remove CDISC Synonym Nipple - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12306 CDISC Definition SPEC Specimen Update CDISC Definition One of the two longitudinal folds of skin that form the lateral boundary of the vulva. It extends from the mons pubis to the perineum. (NCI) One of the two longitudinal folds of skin that form the lateral boundary of the vulva. 2017-03-31 CDISC-1670; CDISC-1699 Update C12307 CDISC Definition SPEC Specimen Update CDISC Definition One of the two longitudinal folds of skin located between the labia majora. (NCI) One of the two longitudinal folds of skin located between the labia majora. 2017-03-31 CDISC-1348 Update C12311 CDISC Definition SPEC Specimen Update CDISC Definition The lower part of the uterus occupying the region between the isthmus of the uterus and the vagina. It is divided into supravaginal and vaginal portions. (NCI) The portion of the uterus (or uterine horns) that empties into the vagina. 2017-03-31 CDISC-1543 Update C12316 CDISC Definition SPEC Specimen Update CDISC Definition The Corpus uteri, or body of uterus, is the part of the uterus above the isthmus, comprising about two thirds of the non-pregnant organ. (NCI) The body of the uterus. 2017-03-31 CDISC-1741 Update C12323 CDISC Definition SPEC Specimen Update CDISC Definition A covering fold of skin, often used alone to designate the preputium penis. (NCI) A fold of skin covering the end of the penis. 2017-03-31 CDISC-1543 Update C12328 CDISC Definition SPEC Specimen Update CDISC Definition A crescent-like structure located in the upper and posterior surfaces of the testis. It consists of the efferent ductules and the duct of the epididymis. It facilitates the maturation of sperm that is produced in the testis. (NCI) A crescent-like structure located adjacent to the testis. It consists of a single highly coiled duct and is divided into 3 regions: caput (head), corpus (body) and cauda (tail). 2017-03-31 CDISC-1543 Update C12341 CDISC Definition SPEC Specimen Update CDISC Definition A thin, transparent tissue divided into the palpebral conjunctiva (covering the inner side of the eye lid) and the bulbar conjunctiva (covering the eyeball). (NCI) A thin tissue divided into the palpebral conjunctiva (covering the inner side of the eye lid) and the bulbar conjunctiva (covering the eyeball). (NCI) 2017-03-31 CDISC-1543 Update C12341 CDISC Synonym SPEC Specimen Remove CDISC Synonym Conjunctiva - - - 2017-03-31 CDISC-1543 Update C12342 CDISC Definition SPEC Specimen Update CDISC Definition A dome-shaped, transparent, avascular tissue covering the front of the eye. It is composed of five layers: squamous epithelium, Bowman's membrane, stroma, Descemet's membrane, and endothelium. Refraction of light contributing to eye's focusing ability is its characteristic function. It contains unmyelinated nerve endings which are responsible for the high sensitivity of the tissue. (NCI) The transparent, avascular tissue covering the front of the eye and is continuous with the sclera. 2017-03-31 CDISC-1543 Update C12342 CDISC Synonym SPEC Specimen Remove CDISC Synonym Cornea - - - 2017-03-31 CDISC-1543 Update C12345 CDISC Definition SPEC Specimen Update CDISC Definition Tissue located behind the iris and composed of muscle and epithelium. Its functions include the production of aqueous humor and changing the shape of the crystalline lens. (NCI) Circumferential tissue located behind the iris and composed of muscle and epithelium. 2017-03-31 CDISC-1670; CDISC-1699 Update C12346 CDISC Definition SPEC Specimen Update CDISC Definition Paired, almond-shaped exocrine glands situated superior and posterior to each orbit of the eye that produce and secrete the watery serous component of tears. (NCI) The exocrine glands that produce the watery serous component of tears. 2017-03-31 CDISC-1348 Update C12347 CDISC Definition SPEC Specimen Update CDISC Definition The bony cavity of the skull which contains the eye, anterior portion of the optic nerve, ocular muscles and ocular adnexa. Seven bones contribute to the structure of the orbit: the frontal, maxillary, zygomatic, sphenoid, lacrimal, ethmoid, and palatine bones. (NCI) The bony cavity that contains the eye and its associated structures. 2017-03-31 CDISC-1543 Update C12347 CDISC Synonym SPEC Specimen Remove CDISC Synonym Orbital Cavity - - - 2017-03-31 CDISC-1348 Add C12351 Term SPEC Specimen Add new term to existing codelist - - - BRAIN, CEREBRUM Replaces BRAIN, CEREBRUM (C49136), which has been retired from this codelist. 2017-03-31 CDISC-1348 Add C12366 Term SPEC Specimen Add new term to existing codelist - - - BONE Replaces BONE (C13076), which has been retired from this codelist. 2017-03-31 CDISC-1670; CDISC-1699 Add C12367 Term SPEC Specimen Add new term to existing codelist - - - GLAND, MAMMARY Replaces GLAND, MAMMARY (C12370), which has been retired from this codelist. 2017-03-31 CDISC-1670; CDISC-1699 Remove C12370 Term SPEC Specimen Remove term entirely from codelist GLAND, MAMMARY - - - Retire existing term and replace with a new concept GLAND, MAMMARY (C12367). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1543 Update C12374 CDISC Definition SPEC Specimen Update CDISC Definition The supporting or framework tissue of the body, formed of fibrous and ground substance with more or less numerous cells of various kinds; it is derived from the mesenchyme, and this in turn from the mesoderm; the varieties of connective tissue are: areolar or loose; adipose; dense, regular or irregular, white fibrous; elastic; mucous; and lymphoid tissue; cartilage; and bone; the blood and lymph may be regarded as connective tissues the ground substance of which is a liquid. The supporting or framework tissue of the body, formed of fibrous and ground substance with a variety of cell types. The varieties of connective tissue are: areolar or loose; adipose; dense, regular or irregular, white fibrous; elastic; mucous; lymphoid tissue; cartilage; bone. 2017-03-31 CDISC-1543 Add C12376 Term SPEC Specimen Add new term to existing codelist - - - DUCT, BILE Replaces DUCT, BILE (C43615), which has been retired from this codelist. 2017-03-31 CDISC-1670; CDISC-1699 Update C12377 CDISC Definition SPEC Specimen Update CDISC Definition A pear-shaped organ located under the liver that stores and concentrates bile secreted by the liver. From the gallbladder the bile is delivered through the bile ducts into the intestine thereby aiding the digestion of fat-containing foods. (NCI) A sac-like organ located adjacent to the liver that stores and concentrates bile produced by the liver. 2017-03-31 CDISC-1670; CDISC-1699 Update C12377 CDISC Synonym SPEC Specimen Remove CDISC Synonym Gallbladder - - - 2017-03-31 CDISC-1670; CDISC-1699 Add C12379 Term SPEC Specimen Add new term to existing codelist - - - LARGE INTESTINE Replaces LARGE INTESTINE (C32931), which has been retired from this codelist. 2017-03-31 CDISC-1670; CDISC-1699 Update C12380 CDISC Definition SPEC Specimen Update CDISC Definition Small tissue projection existing as a cecal diverticulum with a questionable history of vestigial versus specialized organ. (NCI) A pouch-like tissue attached to the cecum, which may exist as a diverticulum. 2017-03-31 CDISC-1670; CDISC-1699 Update C12380 CDISC Synonym SPEC Specimen Remove CDISC Synonym Appendix - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12381 CDISC Definition SPEC Specimen Update CDISC Definition A blind pouch-like commencement of the colon in the right lower quadrant of the abdomen at the end of the small intestine and the start of the large intestine. (OMD) The pouch-like portion of the proximal large intestine opening into the colon. 2017-03-31 CDISC-1670; CDISC-1699 Update C12381 CDISC Synonym SPEC Specimen Remove CDISC Synonym Cecal - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12381 CDISC Synonym SPEC Specimen Remove CDISC Synonym Cecum - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12382 CDISC Definition SPEC Specimen Update CDISC Definition The part of the large intestine measured from the cecum to the rectum consisting of ascending, transverse, descending and sigmoid portions. The purpose of the colon is to remove water from digested food prior to excretion. (NCI) The portion of the large intestine which extends from the cecum (or small intestine in animals that don't have a cecum) to the rectum. 2017-03-31 CDISC-1670; CDISC-1699 Update C12382 CDISC Synonym SPEC Specimen Remove CDISC Synonym Colon - - - 2017-03-31 CDISC-2363; CDISC-2331 Add C12386 Term SPEC Specimen Add new term to existing codelist - - - SMALL INTESTINE Replaces SMALL INTESTINE (C33573), which has been retired from this codelist. 2017-03-31 CDISC-2331 Update C12387 CDISC Definition SPEC Specimen Update CDISC Definition The final section of the small intestine. (NCI) The portion of the small intestine between the jejunum and large intestine. 2017-03-31 CDISC-2331 Update C12387 CDISC Synonym SPEC Specimen Remove CDISC Synonym Ileum - - - 2017-03-31 CDISC-2331 Update C12388 CDISC Definition SPEC Specimen Update CDISC Definition The portion of the small intestine that extends from the duodenum to the ileum. (NCI) The portion of the small intestine between the duodenum and ileum. 2017-03-31 CDISC-2331 Update C12388 CDISC Synonym SPEC Specimen Remove CDISC Synonym Jejunum - - - 2017-03-31 CDISC-1543 Add C12389 Term SPEC Specimen Add new term to existing codelist - - - ESOPHAGUS Replaces ESOPHAGUS (C32543), which has been retired from this codelist. 2017-03-31 CDISC-1670; CDISC-1699 Update C12390 CDISC Definition SPEC Specimen Update CDISC Definition The terminal portion of the gastrointestinal tract, extending from the rectosigmoid junction to the anal canal. (NCI) The terminal portion of the large intestine extending from the terminus of the colon to the anus or anal canal. 2017-03-31 CDISC-2363 Add C12391 Term SPEC Specimen Add new term to existing codelist - - - STOMACH Replaces STOMACH (C32664), which has been retired from this codelist. 2017-03-31 CDISC-1670; CDISC-1699 Add C12392 Term SPEC Specimen Add new term to existing codelist - - - LIVER Replaces LIVER (C32735), which has been retired from this codelist. 2017-03-31 CDISC-1741 Update C12393 CDISC Definition SPEC Specimen Update CDISC Definition An organ located adjacent to the stomach that contains both exocrine and endocrine tissue. A digestive organ in the abdomen that has both endocrine and exocrine functions. 2017-03-31 CDISC-1543 Update C12394 CDISC Definition SPEC Specimen Update CDISC Definition A sense organ needed for the detection of sound and for establishing balance. The outer ear consists of the auricle, the ear canal as well as the tympanic membrane. The middle ear is made up of an air-filled cavity behind the tympanic membrane that contains the ossicles (malleus, incus and stapes). The inner ear is made up of the cochlea needed for hearing and the vestibular apparatus required for balance. (NCI) A sensory organ that contains auditory and vestibular apparatuses. 2017-03-31 CDISC-1543 Update C12394 CDISC Synonym SPEC Specimen Remove CDISC Synonym Ear - - - 2017-03-31 CDISC-1543 Update C12395 CDISC Definition SPEC Specimen Update CDISC Definition The snail shell-shaped auditory component of the inner ear. It contains the sensory organ of hearing. (NCI) The snail shell-shaped auditory component of the inner ear. 2017-03-31 CDISC-1670; CDISC-1699 Add C12398 Term SPEC Specimen Add new term to existing codelist - - - GLAND, PINEAL Replaces GLAND, PINEAL (C41834), which has been retired from this codelist. 2017-03-31 CDISC-1670; CDISC-1699 Update C12399 CDISC Definition SPEC Specimen Update CDISC Definition Pea-sized endocrine gland located at the base of the brain in the pituitary fossa. It produces and secretes hormones such as oxytocin and vasopressin, to regulate the activities of the hypothalamus. (NCI) A small endocrine gland extending from the hypothalamus at the base of the brain. 2017-03-31 CDISC-1670; CDISC-1699 Add C12400 Term SPEC Specimen Add new term to existing codelist - - - GLAND, THYROID Replaces GLAND, THYROID (C33785), which has been retired from this codelist. 2017-03-31 CDISC-1543 Update C12401 CDISC Definition SPEC Specimen Update CDISC Definition The organ of sight or vision. (NCI) The sensory organ of vision. 2017-03-31 CDISC-1543 Update C12401 CDISC Synonym SPEC Specimen Remove CDISC Synonym Eye - - - 2017-03-31 CDISC-1741 Update C12403 CDISC Definition SPEC Specimen Update CDISC Definition One of a pair of tubes that extend from the uterus to each of the ovaries. Following ovulation the egg travels down the fallopian tube to the uterus where fertilization may or may not occur. (NCI) The tube through which eggs pass from an ovary. 2017-03-31 CDISC-1741 Update C12404 CDISC Definition SPEC Specimen Update CDISC Definition One of the paired female reproductive glands containing the ova or germ cells; the ovary's stroma is a vascular connective tissue containing numbers of ovarian follicles enclosing the ova. (NCI) The female gonad. 2017-03-31 CDISC-1741 Update C12404 CDISC Synonym SPEC Specimen Remove CDISC Synonym Ovary - - - 2017-03-31 CDISC-2331 Update C12408 CDISC Definition SPEC Specimen Update CDISC Definition The external, visible part of the female genitalia surrounding the urethral and vaginal opening. The vulva includes the clitoris and inner as well as outer labia. (NCI) The external, visible part of the female genitalia surrounding the urethral and vaginal opening(s). 2017-03-31 CDISC-2331 Update C12408 CDISC Synonym SPEC Specimen Remove CDISC Synonym External Genitalia - - - 2017-03-31 CDISC-2331 Update C12408 CDISC Synonym SPEC Specimen Remove CDISC Synonym Vulva - - - 2017-03-31 CDISC-1741 Add C12409 Term SPEC Specimen Add new term to existing codelist - - - PENIS Replaces PENIS (C49269), which has been retired from this codelist. 2017-03-31 CDISC-1670; CDISC-1699 Add C12410 Term SPEC Specimen Add new term to existing codelist - - - GLAND, PROSTATE Replaces GLAND, PROSTATE (C33414), which has been retired from this codelist. 2017-03-31 CDISC-2710 Update C12412 CDISC Definition SPEC Specimen Update CDISC Definition Either of the paired male reproductive glands that produce the male germ cells and the male hormones. (NCI) The male gonad. 2017-03-31 CDISC-2710 Update C12412 CDISC Synonym SPEC Specimen Remove CDISC Synonym Testis - - - 2017-03-31 CDISC-2363; CDISC-2331 Add C12414 Term SPEC Specimen Add new term to existing codelist - - - URINARY BLADDER Replaces URINARY BLADDER (C32209), which has been retired from this codelist. 2017-03-31 CDISC-1670; CDISC-1699 Add C12415 Term SPEC Specimen Add new term to existing codelist - - - KIDNEY Replaces KIDNEY (C33461), which has been retired from this codelist. 2017-03-31 CDISC-2331 Update C12416 CDISC Definition SPEC Specimen Update CDISC Definition The thick-walled tube that carries urine from each kidney to the bladder. (NCI) The tube that extends from each kidney to the urinary bladder. 2017-03-31 CDISC-2331 Update C12416 CDISC Synonym SPEC Specimen Remove CDISC Synonym Ureter - - - 2017-03-31 CDISC-2331 Update C12417 CDISC Definition SPEC Specimen Update CDISC Definition The tube carrying urine from the bladder to outside of the body. (NCI) The tube that extends from the urinary bladder to the urethral opening. 2017-03-31 CDISC-2331 Update C12417 CDISC Synonym SPEC Specimen Remove CDISC Synonym Urethra - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12419 CDISC Definition SPEC Specimen Update CDISC Definition The anterior and superior part of a human or animal bearing the mouth, the brain and sensory organs. The portion of the body containing the mouth, the brain and multiple sensory organs. 2017-03-31 CDISC-1670; CDISC-1699 Update C12419 CDISC Synonym SPEC Specimen Remove CDISC Synonym Head - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12420 CDISC Definition SPEC Specimen Update CDISC Definition The cartilaginous structure of the respiratory tract between the pharynx and the trachea. It contains elastic vocal cords required for sound production. (NCI) The cartilaginous structure of the respiratory tract between the pharynx and the trachea. 2017-03-31 CDISC-1670; CDISC-1699 Update C12420 CDISC Synonym SPEC Specimen Remove CDISC Synonym Larynx - - - 2017-03-31 CDISC-1348 Update C12421 CDISC Definition SPEC Specimen Update CDISC Definition The cavity located at the upper end of the alimentary canal, behind the teeth and gums that is bounded on the outside by the lips, above by the hard and soft palates and below by the tongue. (NCI) The cavity of the mouth. 2017-03-31 CDISC-1348 Update C12421 CDISC Synonym SPEC Specimen Remove CDISC Synonym Oral Cavity - - - 2017-03-31 CDISC-2331 Update C12422 CDISC Definition SPEC Specimen Update CDISC Definition The muscular organ located in the floor of the mouth and serving as the principal organ of taste and modification of the voice in speech. (NCI) The muscular organ in the mouth used in taste perception and food ingestion. 2017-03-31 CDISC-2331 Update C12422 CDISC Synonym SPEC Specimen Remove CDISC Synonym Tongue - - - 2017-03-31 CDISC-1741 Update C12423 CDISC Definition SPEC Specimen Update CDISC Definition The part of the pharynx in the back of the throat, at and above the soft palate. The nasopharynx is continuous with the nasal passages. (NCI) The part of the pharynx above the soft palate, which is continuous with the nasal cavity and extends to the oropharynx. 2017-03-31 CDISC-1741 Update C12423 CDISC Synonym SPEC Specimen Remove CDISC Synonym Nasopharynx - - - 2017-03-31 CDISC-1348 Update C12424 CDISC Definition SPEC Specimen Update CDISC Definition The proximal portion of the respiratory passages on either side of the nasal septum lying between the floor of the cranium and the roof of the mouth and extending from the face to the pharynx. The nasal cavity is lined with ciliated mucosa, extending from the nares to the pharynx. (NCI) The upper respiratory tract extending from the nares to the pharynx. 2017-03-31 CDISC-1348 Update C12424 CDISC Synonym SPEC Specimen Remove CDISC Synonym Nasal Cavity - - - 2017-03-31 CDISC-1741 Update C12425 CDISC Definition SPEC Specimen Update CDISC Definition A hollow tube that starts posterior to the mouth and nasal cavity and ends superior to the trachea and esophagus. (NCI) A passageway in the head and neck that includes the nasopharynx, oropharynx and laryngopharynx. 2017-03-31 CDISC-1741 Update C12425 CDISC Synonym SPEC Specimen Remove CDISC Synonym Pharynx - - - 2017-03-31 CDISC-1670; CDISC-1699 Add C12426 Term SPEC Specimen Add new term to existing codelist - - - GLAND, SALIVARY Replaces GLAND, SALIVARY (C33509), which has been retired from this codelist. 2017-03-31 CDISC-1670; CDISC-1699 Update C12427 CDISC Definition SPEC Specimen Update CDISC Definition The largest of the three paired salivary glands, located in front of the ear. (NCI) The salivary gland located adjacent to the ear. 2017-03-31 CDISC-1670; CDISC-1699 Update C12427 CDISC Synonym SPEC Specimen Remove CDISC Synonym Parotid Gland - - - 2017-03-31 CDISC-2331 Update C12428 CDISC Definition SPEC Specimen Update CDISC Definition The fibrocartilaginous, mucous-lined tube passing from the larynx to the bronchi. (NCI) The fibrocartilaginous tube extending from the larynx to the bronchi. 2017-03-31 CDISC-2331 Update C12428 CDISC Synonym SPEC Specimen Remove CDISC Synonym Trachea - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12429 CDISC Definition SPEC Specimen Update CDISC Definition A body region referring to an upper or lower extremity. (NCI) A jointed extremity of the upper/thoracic or lower/pelvic regions. 2017-03-31 CDISC-1670; CDISC-1699 Update C12429 CDISC Synonym SPEC Specimen Add new CDISC Synonym - - - Extremity 2017-03-31 CDISC-1670; CDISC-1699 Update C12429 CDISC Synonym SPEC Specimen Remove CDISC Synonym Extremities - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12429 CDISC Synonym SPEC Specimen Remove CDISC Synonym Limb - - - 2017-03-31 CDISC-1348 Update C12431 CDISC Definition SPEC Specimen Update CDISC Definition The tissue occupying the spaces of bone. It consists of blood vessel sinuses and a network of hematopoietic cells which give rise to the red cells, white cells, and megakaryocytes. (NCI) The tissue occupying the spaces of some bones. It consists of blood vessel sinuses and a network of hematopoietic cells. 2017-03-31 CDISC-1348 Update C12431 CDISC Synonym SPEC Specimen Remove CDISC Synonym Bone Marrow - - - 2017-03-31 CDISC-2363; CDISC-2331 Add C12432 Term SPEC Specimen Add new term to existing codelist - - - SPLEEN Replaces SPLEEN (C34086), which has been retired from this codelist. 2017-03-31 CDISC-2363; CDISC-2331 Add C12433 Term SPEC Specimen Add new term to existing codelist - - - THYMUS Replaces THYMUS (C33952), which has been retired from this codelist. 2017-03-31 CDISC-1741 Update C12437 CDISC Definition SPEC Specimen Update CDISC Definition Involuntary muscle tissue of the internal organs. It is composed of elongated muscle cells or fibers that are not arranged in a striated pattern and form layers of muscle tissue. The smooth muscle cells contain a contractile apparatus composed of thin and thick filaments and a cytoskeleton composed of intermediate filaments. (NCI) Primarily involuntary, non-striated muscle tissue of the internal organs and blood vessels. 2017-03-31 CDISC-1348 Update C12440 CDISC Submission Value SPEC Specimen Update CDISC Submission Value AMYGDALOID BODY BRAIN, AMYGDALOID BODY 2017-03-31 CDISC-1348 Update C12440 CDISC Definition SPEC Specimen Update CDISC Definition An almond-shaped group of basal nuclei anterior to the inferior horn of the lateral ventricle of the brain, within the temporal lobe. The amygdala is part of the limbic system. (MESH) A group of nuclei adjacent to the lateral ventricle of the brain within the temporal lobe, and is part of the limbic system. 2017-03-31 CDISC-1348 Update C12440 CDISC Synonym SPEC Specimen Add new CDISC Synonym - - - Amygdala 2017-03-31 CDISC-1348 Update C12440 CDISC Synonym SPEC Specimen Add new CDISC Synonym - - - Amygdaloid Body 2017-03-31 CDISC-1348 Update C12442 CDISC Definition SPEC Specimen Update CDISC Definition The lower portion of the brainstem located between the pons and brainstem. This structure contains several descending and ascending tracts, lower cranial nerve nuclei, a significant proportion of the reticular system of the brainstem and other structures. (NCI) The portion of the brainstem between the pons and cervical spinal cord. 2017-03-31 CDISC-1348 Update C12442 CDISC Synonym SPEC Specimen Remove CDISC Synonym Medulla Oblongata - - - 2017-03-31 CDISC-1348 Update C12444 CDISC Definition SPEC Specimen Update CDISC Definition A curved gray matter structure of the temporal lobe lying on the floor of the lateral ventricle of the brain. (NCI) A curved gray matter structure of the cerebrum that is part of the limbic system. 2017-03-31 CDISC-1348 Update C12444 CDISC Synonym SPEC Specimen Remove CDISC Synonym Hippocampus - - - 2017-03-31 CDISC-1348 Add C12445 Term SPEC Specimen Add new term to existing codelist - - - BRAIN, CEREBELLUM Replaces BRAIN, CEREBELLUM (C49137), which has been retired from this codelist. 2017-03-31 CDISC-1543 Update C12446 CDISC Submission Value SPEC Specimen Update CDISC Submission Value CORPUS CALLOSUM BRAIN, CORPUS CALLOSUM 2017-03-31 CDISC-1543 Update C12446 CDISC Definition SPEC Specimen Update CDISC Definition A white matter structure within the cleft that separates the left and right cerebral hemispheres in the mammalian brain. It is composed of a wide, flat bundle of 200-250 million axonal projections. (NCI) A white matter structure within the brain that connects the left and right cerebral hemispheres. 2017-03-31 CDISC-1348 Update C12447 CDISC Definition SPEC Specimen Update CDISC Definition Clusters of neurons comprising the globus pallidus, putamen, caudate, nucleus accumbens, substantia nigra and subthalamic nucleus. They are involved with high level aspects of inhibitory motor activity in coordination with the excitation commands issued from the cerebellum. (NCI) Clusters of neurons comprising the globus pallidus, putamen, caudate, nucleus accumbens, substantia nigra and subthalamic nucleus. 2017-03-31 CDISC-1348 Update C12447 CDISC Synonym SPEC Specimen Remove CDISC Synonym Basal Ganglia - - - 2017-03-31 CDISC-1348 Update C12453 CDISC Definition SPEC Specimen Update CDISC Definition A large cell mass extending forward, over the dorsal surface of the crus cerebri, from the rostral border of the pons into the subthalamic region. It is composed of a dorsal stratum of closely spaced pigmented cells, the pars compacta, and a larger ventral region of widely scattered cells, the pars reticulata. The pars compacta includes numerous cells that project forward to the striatum (caudate nucleus and putamen) and contain dopamine, which acts as the primary neurotransmitter at the synaptic endings. Other, apparently non-dopaminergic cells project to portions of the ventral nucleus of thalamus, the superior colliculus and reticular formation. The nigrostriatal projection is reciprocated by a striatonigral fiber system with multiple neurotransmitters, chief among which is gamma-aminobutyric acid (GABA). The substantia nigra is involved in the metabolic disturbances associated with Parkinson's disease and Huntington's disease. (NCI) The portion of the midbrain composed of two parts, the pars compacta and pars reticulata. 2017-03-31 CDISC-1348 Update C12453 CDISC Synonym SPEC Specimen Remove CDISC Synonym Substantia Nigra - - - 2017-03-31 CDISC-1348 Update C12458 CDISC Definition SPEC Specimen Update CDISC Definition The supervisory center in the brain, rich in ganglia, nerve fibers, and synaptic connections. It is composed of several sections called nuclei, each of which controls a specific function. A small region of the brain composed of multiple nuclei and located underneath the thalamus. 2017-03-31 CDISC-1348 Update C12458 CDISC Synonym SPEC Specimen Remove CDISC Synonym Hypothalamus - - - 2017-03-31 CDISC-1348 Update C12459 CDISC Definition SPEC Specimen Update CDISC Definition An ovoid mass composed predominantly of gray substance and associated laminae of white substance. The thalamus is divided into anterior, medial, and lateral parts. The function of the thalamus is to relay sensory impulses and cerebellar and basal ganglia projections to the cerebral cortex. The thalamus is positioned within the posterior part of the diencephalon forming most of each lateral wall of the third ventricle. (NCI) The portion of the diencephalon forming most of each lateral wall of the third ventricle. 2017-03-31 CDISC-1348 Update C12459 CDISC Synonym SPEC Specimen Remove CDISC Synonym Thalamus - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12462 CDISC Synonym SPEC Specimen Add new CDISC Synonym - - - Spinal Ganglion 2017-03-31 CDISC-1670; CDISC-1699 Update C12462 CDISC Synonym SPEC Specimen Remove CDISC Synonym Dorsal Root - - - 2017-03-31 CDISC-2331 Update C12464 CDISC Definition SPEC Specimen Update CDISC Definition The elongated, approximately cylindrical part of the central nervous system of vertebrates that lies in the vertebral canal and from which the spinal nerves emerge. (NCI) The portion of the central nervous system that lies within the vertebral canal and from which the spinal nerves emerge. 2017-03-31 CDISC-1741 Add C12466 Term SPEC Specimen Add new term to existing codelist - - - NERVE Replaces NERVE (C13052), which has been retired from this codelist. 2017-03-31 CDISC-1670; CDISC-1699 Add C12468 Term SPEC Specimen Add new term to existing codelist - - - LUNG Replaces LUNG (C33024), which has been retired from this codelist. 2017-03-31 CDISC-1741 Update C12469 CDISC Definition SPEC Specimen Update CDISC Definition The tissue that lines the wall of the thoracic cavity and the surface of the lungs. (NCI) The serous membrane that lines the wall of the thoracic cavity and the surface of the lungs. 2017-03-31 CDISC-1741 Update C12469 CDISC Synonym SPEC Specimen Remove CDISC Synonym Pleural Tissue - - - 2017-03-31 CDISC-1348 Update C12472 CDISC Definition SPEC Specimen Update CDISC Definition A specialized form of connective tissue consisting primarily of adipocytes (fat cells), surrounded by a meshwork of collagen fibers. (NCI) Connective tissue consisting primarily of adipocytes (fat cells) and supporting structural matrix. 2017-03-31 CDISC-1348 Update C12472 CDISC Synonym SPEC Specimen Remove CDISC Synonym Adipose Tissue - - - 2017-03-31 CDISC-2331 Update C12473 CDISC Submission Value SPEC Specimen Update CDISC Submission Value TISSUE, SYNOVIAL SYNOVIAL MEMBRANE 2017-03-31 CDISC-2331 Update C12473 CDISC Definition SPEC Specimen Update CDISC Definition The inner layer of the connective tissue that seals the joint. (NCI) The connective tissue and synoviocytes that line the inner surface of the joint capsule. 2017-03-31 CDISC-1670; CDISC-1699 Update C12499 CDISC Definition SPEC Specimen Update CDISC Definition The portion of the ear located within the temporal bone that is involved in both hearing and balance and includes the semicircular canals, vestibule, and cochlea. (from American Heritage Dictionary online) The innermost portion of the ear that contains the vestibule, cochlea and semicircular canals. 2017-03-31 CDISC-1670; CDISC-1699 Update C12499 CDISC Synonym SPEC Specimen Remove CDISC Synonym Cochlea - - - 2017-03-31 CDISC-1543 Update C12500 CDISC Definition SPEC Specimen Update CDISC Definition A tubular structure that runs from the middle ear to the nasopharynx and is approximately 3-4 cm length. Its lumen is roughly triangular and has average diameter of 2-3 mm. The lumen is lined by ciliated pseudostratified, columnar epithelium, which sweeps material from the middle ear to the nasopharynx. It is functionally collapsed at rest, with slight negative pressure present in the middle ear, and opens during swallowing, sneezing, and yawning. It serves to ventilate pressure differences between the middle ear and nasopharynx. This tube also allows middle ear secretions to drain into the nasopharynx. A tubular structure that extends from the middle ear to the nasopharynx. 2017-03-31 CDISC-2363; CDISC-2331 Add C12506 Term SPEC Specimen Add new term to existing codelist - - - TOOTH Replaces TOOTH (C33794), which has been retired from this codelist. 2017-03-31 CDISC-1348 Update C12510 CDISC Definition SPEC Specimen Update CDISC Definition The uppermost portion of the brainstem located between the pons and the diencephalon. The midbrain contains the cerebral peduncles, oculomotor, trochlear and red nuclei, substantia nigra and various other nuclei and tracts. (NCI) The portion of the brainstem between the pons and diencephalon. 2017-03-31 CDISC-1348 Update C12510 CDISC Synonym SPEC Specimen Remove CDISC Synonym Midbrain - - - 2017-03-31 CDISC-1348 Update C12511 CDISC Definition SPEC Specimen Update CDISC Definition The middle portion of the brainstem located between the midbrain and the medulla oblongata. The portion of the brainstem between the midbrain and medulla oblongata. 2017-03-31 CDISC-1348 Update C12664 CDISC Definition SPEC Specimen Update CDISC Definition The portion of the body that lies between the thorax and the pelvis. (NCI) The body cavity between the thoracic and pelvic cavities in mammals. 2017-03-31 CDISC-1348 Update C12664 CDISC Synonym SPEC Specimen Remove CDISC Synonym Abdominal Cavity - - - 2017-03-31 CDISC-1670; CDISC-1699 Add C12666 Term SPEC Specimen Add new term to existing codelist - - - GLAND, ADRENAL Replaces GLAND, ADRENAL (C32051), which has been retired from this codelist. 2017-03-31 CDISC-1543 Update C12667 CDISC Definition SPEC Specimen Update CDISC Definition The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109) (NCI) The space in the eye filled with aqueous humor and bounded by the cornea, a small portion of the sclera, a small portion of the ciliary body, the iris and lens. (Cline et al., Dictionary of Visual Science, 4th ed, p109) 2017-03-31 CDISC-1348 Update C12669 CDISC Definition SPEC Specimen Update CDISC Definition The major arterial trunk that carries oxygenated blood from the left ventricle into the ascending aorta behind the heart, the aortic arch, through the thorax as the descending aorta and through the abdomen as the abdominal aorta; it bifurcates into the left and right common iliac arteries. (NCI) The major artery of the body; it arises from the left ventricle of the heart and terminally bifurcates into the common iliac arteries. 2017-03-31 CDISC-1348 Update C12669 CDISC Synonym SPEC Specimen Remove CDISC Synonym Aorta - - - 2017-03-31 CDISC-2331 Update C12670 CDISC Definition SPEC Specimen Update CDISC Definition A valve that is located between and controls the flow of blood from the left ventricle of the heart and the aorta. (NCI) A cardiac valve located between the left ventricle and the aorta. 2017-03-31 CDISC-2363 Add C12679 Term SPEC Specimen Add new term to existing codelist - - - VESSEL, BLOOD Replaces VESSEL, BLOOD (C32213), which has been retired from this codelist. 2017-03-31 CDISC-1348 Update C12681 CDISC Definition SPEC Specimen Update CDISC Definition An artery originating at the axillary artery and branching into the radial and ulnar arteries. (NCI) An artery of the forelimb; in general it arises from the axillary artery and branches to form the radial and ulnar arteries. 2017-03-31 CDISC-1348 Update C12681 CDISC Synonym SPEC Specimen Remove CDISC Synonym Brachial Artery - - - 2017-03-31 CDISC-1741 Update C12682 CDISC Submission Value SPEC Specimen Update CDISC Submission Value NERVE, BRACHIAL NERVE, BRACHIAL PLEXUS 2017-03-31 CDISC-1741 Update C12682 CDISC Definition SPEC Specimen Update CDISC Definition A nerve network originating from C5 to T1 that supplies cutaneous and muscular innervation to the arm and hand. (NCI) A nerve network originating from spinal nerves in the cervical and thoracic vertebrae and giving rise to multiple nerves that innervate the arm/forelimb. 2017-03-31 CDISC-1348 Update C12683 CDISC Definition SPEC Specimen Update CDISC Definition Tubular structure in continuation with the trachea, serving as air passage. It terminates in the lung (terminal bronchiole). (NCI) Tubular structure in continuation with the trachea, serving as an air passage. 2017-03-31 CDISC-1348 Update C12683 CDISC Synonym SPEC Specimen Remove CDISC Synonym Bronchus - - - 2017-03-31 CDISC-1348 Update C12687 CDISC Definition SPEC Specimen Update CDISC Definition One of two arteries that supply oxygenated blood to the head and neck; the left common carotid branches from the aorta and the right common carotid from the innominate (brachiocephalic artery). (NCI) An artery of the mediastinum and neck; in general it arises as a primary or secondary branch of the aortic arch and branches into the internal and external carotid arteries. 2017-03-31 CDISC-1348 Update C12687 CDISC Synonym SPEC Specimen Add new CDISC Synonym - - - Common Carotid Artery 2017-03-31 CDISC-1348 Update C12687 CDISC Synonym SPEC Specimen Remove CDISC Synonym Carotid Artery - - - 2017-03-31 CDISC-1348 Update C12688 CDISC Definition SPEC Specimen Update CDISC Definition Any of the small bones of the wrist joint, located between the radius and the ulna and the metacarpus. (NCI) Any of the bones of the joint located between the radius and ulna and metacarpus. 2017-03-31 CDISC-1348 Update C12694 CDISC Definition SPEC Specimen Update CDISC Definition Blood vessels forming villous structures in the third, fourth, and lateral ventricles of the brain. (NCI) Blood vessels and ependyma forming villous structures in the ventricles of the brain. 2017-03-31 CDISC-1348 Update C12694 CDISC Synonym SPEC Specimen Remove CDISC Synonym Choroid Plexus - - - 2017-03-31 CDISC-2710 Update C12698 CDISC Definition SPEC Specimen Update CDISC Definition The extrahepatic duct that is formed by the juncture of the cystic and hepatic ducts and extends to the duodenum. A duct that conveys bile from the convergence of the cystic and hepatic duct to the duodenum. 2017-03-31 CDISC-1741 Update C12702 CDISC Definition SPEC Specimen Update CDISC Definition Fibromuscular tissue that separates the thoracic from the abdominal cavity. It increases the volume of the thoracic cavity through contractions, thus facilitating respiration. A musculotendinous sheet separating the thoracic cavity from the abdominal cavity. 2017-03-31 CDISC-1543 Update C12713 CDISC Definition SPEC Specimen Update CDISC Definition A thin membrane of skin with the purpose of covering and protecting an eye. (NCI) The section of skin, containing muscle and conjunctiva, that covers and protects the eye. 2017-03-31 CDISC-1543 Update C12713 CDISC Synonym SPEC Specimen Remove CDISC Synonym Eyelid - - - 2017-03-31 CDISC-1741 Update C12714 CDISC Definition SPEC Specimen Update CDISC Definition The 7th cranial nerve. The facial nerve has two parts, the larger motor root which may be called the facial nerve proper, and the smaller intermediate or sensory root. Together they provide efferent innervation to the muscles of facial expression and to the lacrimal and salivary glands, and convey afferent information for taste from the anterior two-thirds of the tongue and for touch from the external ear. (MeSH) A cranial nerve extending from the brain stem between the pons and medulla, which innervates the facial muscles, glands and the tongue. 2017-03-31 CDISC-1348 Update C12715 CDISC Definition SPEC Specimen Update CDISC Definition An artery that starts within the inguinal region and extends to the lower extremities. (NCI) An artery of the thigh; in general it arises from the external iliac artery distal to the inguinal ligment and continues as the popliteal artery. 2017-03-31 CDISC-1348 Update C12715 CDISC Synonym SPEC Specimen Remove CDISC Synonym Femoral Artery - - - 2017-03-31 CDISC-2331 Update C12716 CDISC Definition SPEC Specimen Update CDISC Definition A vein that starts within the inguinal region and extends to the lower extremities. (NCI) A vein of the thigh; in general it arises from the popliteal vein and drains into the external iliac vein. 2017-03-31 CDISC-2331 Update C12716 CDISC Synonym SPEC Specimen Remove CDISC Synonym Femoral Vein - - - 2017-03-31 CDISC-1348 Update C12717 CDISC Definition SPEC Specimen Update CDISC Definition The upper leg bone positioned between the pelvis and the knee. (NCI) The bone positioned between the pelvis and the femorotibial joint. 2017-03-31 CDISC-1348 Update C12717 CDISC Synonym SPEC Specimen Remove CDISC Synonym Femur - - - 2017-03-31 CDISC-1348 Update C12718 CDISC Definition SPEC Specimen Update CDISC Definition The small, lateral calf bone extending from the knee to the ankle. (NCI) The long bone that is lateral to the tibia. 2017-03-31 CDISC-1348 Update C12718 CDISC Synonym SPEC Specimen Remove CDISC Synonym Fibula - - - 2017-03-31 CDISC-2490 Update C12725 CDISC Definition SPEC Specimen Update CDISC Definition The gamete-producing tissues, ovary or testis. (MeSH) A reproductive organ that produces gametes. 2017-03-31 CDISC-1670; CDISC-1699 Update C12727 CDISC Definition SPEC Specimen Update CDISC Definition A hollow muscular organ which receives the blood from the veins and propels it into the arteries. It is divided by a musculomembranous septum into two halves -- right or venous and left or arterial -- each of which consists of a receiving chamber (atrium) and an ejecting chamber (ventricle). (NCI) A hollow muscular organ which receives the blood from the veins and pumps it into the arteries. 2017-03-31 CDISC-1670; CDISC-1699 Update C12727 CDISC Synonym SPEC Specimen Remove CDISC Synonym Cardiac - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12727 CDISC Synonym SPEC Specimen Remove CDISC Synonym Heart - - - 2017-03-31 CDISC-2331 Update C12729 CDISC Definition SPEC Specimen Update CDISC Definition Any of the four heart valves, including the two atrioventricular valves and the two semilunar valves, that regulate the flow of blood through the chambers of the heart. (NCI) A valve located in the heart. 2017-03-31 CDISC-1348 Update C12731 CDISC Definition SPEC Specimen Update CDISC Definition The upper arm bone between the shoulder and elbow. (NCI) The bone between the scapulohumeral and humeroulnar joints. 2017-03-31 CDISC-1348 Update C12731 CDISC Synonym SPEC Specimen Remove CDISC Synonym Humerus - - - 2017-03-31 CDISC-1348 Update C12733 CDISC Definition SPEC Specimen Update CDISC Definition A branch of the abdominal aorta that supplies blood to the lower trunk and the legs. (NCI) An artery of the pelvic region and legs/hindlimbs; in general it arises from the bifurcation of the aorta and branches into the external and internal iliac arteries. 2017-03-31 CDISC-2363 Add C12736 Term SPEC Specimen Add new term to existing codelist - - - INTESTINE Replaces INTESTINE (C49478), which has been retired from this codelist. 2017-03-31 CDISC-1543 Update C12737 CDISC Definition SPEC Specimen Update CDISC Definition The colored disc of the eye composed of connective tissue, epithelium, and endothelium. It separates the anterior chamber from the posterior chamber. (NCI) The tissue in the eye that separates the anterior chamber from the posterior chamber. 2017-03-31 CDISC-2331 Update C12738 CDISC Definition SPEC Specimen Update CDISC Definition Veins in the neck which drain the brain, face, and neck into the brachiocephalic or subclavian veins. (NCI) One of the veins of the neck; in general it arises from the junction of the maxillary and linguofacial veins and drains into the brachiocephalic or the cranial caval vein. 2017-03-31 CDISC-1543 Update C12743 CDISC Definition SPEC Specimen Update CDISC Definition A biconvex transparent structure of the eye through which light is focused on the retina. The lens sits behind the iris and is supported by the zonule, which connects it to the ciliary body. The lens is an avascular structure. (NCI) The structure of the eye through which light is focused onto the retina. 2017-03-31 CDISC-1543 Update C12743 CDISC Synonym SPEC Specimen Remove CDISC Synonym Lens - - - 2017-03-31 CDISC-1543 Update C12743 CDISC Synonym SPEC Specimen Remove CDISC Synonym Lens Of Eye - - - 2017-03-31 CDISC-1670; CDISC-1699 Add C12745 Term SPEC Specimen Add new term to existing codelist - - - LYMPH NODE Replaces LYMPH NODE (C33034), which has been retired from this codelist. 2017-03-31 CDISC-1741 Update C12748 CDISC Definition SPEC Specimen Update CDISC Definition A group of organs surrounded by loose connective tissue, separating the two pleural sacs, between the sternum anteriorly and the vertebral column posteriorly as well as from the thoracic inlet superiorly to the diaphragm inferiorly. The mediastinum contains the heart and pericardium, the bases of the great vessels, the trachea and bronchi, esophagus, thymus, lymph nodes, thoracic duct, phrenic and vagus nerves, and other structures and tissues. (NCI) The central region of the thoracic cavity of mammals containing a group of organs surrounded by loose connective tissue, which separates the two pleural sacs. 2017-03-31 CDISC-1741 Update C12748 CDISC Synonym SPEC Specimen Remove CDISC Synonym Mediastinum - - - 2017-03-31 CDISC-2331 Update C12753 CDISC Submission Value SPEC Specimen Update CDISC Submission Value VALVE, MITRAL VALVE, LEFT ATRIOVENTRICULAR 2017-03-31 CDISC-2331 Update C12753 CDISC Definition SPEC Specimen Update CDISC Definition A dual-flap valve of the heart that regulates the flow of blood between the left atrium and the left ventricle of the heart. (NCI) A cardiac valve located between the left atrium and ventricle. 2017-03-31 CDISC-2331 Update C12753 CDISC Synonym SPEC Specimen Add new CDISC Synonym - - - Mitral Valve 2017-03-31 CDISC-1741 Update C12760 CDISC Definition SPEC Specimen Update CDISC Definition A portion of the retina at which the axons of the ganglion cells exit the eyeball to form the optic nerve. No light-sensitive photoreceptors are contained within this portion of the retina. (NCI) The portion of the retina at which the axons of the ganglion cells exit the eyeball to form the optic nerve. 2017-03-31 CDISC-1741 Update C12760 CDISC Synonym SPEC Specimen Remove CDISC Synonym Optic Papilla - - - 2017-03-31 CDISC-1741 Update C12760 CDISC Synonym SPEC Specimen Remove CDISC Synonym Second Cranial Nerve - - - 2017-03-31 CDISC-2710 Update C12761 CDISC Definition SPEC Specimen Update CDISC Definition The second cranial nerve. (NCI) A cranial nerve extending between the retina and optic chiasma, which innervates the eye. 2017-03-31 CDISC-2710 Update C12761 CDISC Synonym SPEC Specimen Add new CDISC Synonym - - - Second Cranial Nerve 2017-03-31 CDISC-2710 Update C12761 CDISC Synonym SPEC Specimen Remove CDISC Synonym Optic Nerve - - - 2017-03-31 CDISC-2363 Add C12762 Term SPEC Specimen Add new term to existing codelist - - - OROPHARYNX Replaces OROPHARYNX (C92600), which has been retired from this codelist. 2017-03-31 CDISC-1741 Update C12763 CDISC Definition SPEC Specimen Update CDISC Definition An air-filled cavity adjacent to the nasal cavity lined by a mucous membrane and located in the bones of the skull. There are four paranasal sinuses on each side of the face: ethmoid, frontal, maxillary, and sphenoid sinus. (NCI) The air-filled cavities adjacent to the nasal cavity lined by a mucous membrane and located in the bones of the skull. 2017-03-31 CDISC-1741 Update C12763 CDISC Synonym SPEC Specimen Remove CDISC Synonym Accessory Sinuses - - - 2017-03-31 CDISC-1741 Update C12763 CDISC Synonym SPEC Specimen Remove CDISC Synonym Nasal Cavity - - - 2017-03-31 CDISC-1741 Update C12763 CDISC Synonym SPEC Specimen Remove CDISC Synonym Nasal Sinuses - - - 2017-03-31 CDISC-1741 Update C12763 CDISC Synonym SPEC Specimen Remove CDISC Synonym Paranasal Sinus - - - 2017-03-31 CDISC-1670; CDISC-1699 Add C12765 Term SPEC Specimen Add new term to existing codelist - - - GLAND, PARATHYROID Replaces GLAND, PARATHYROID (C33270), which has been retired from this codelist. 2017-03-31 CDISC-1348 Update C12767 CDISC Definition SPEC Specimen Update CDISC Definition The bony, basin-shaped structure formed by the hipbones and the base of the backbone supporting the lower limbs in humans. (NCI) The bony, basin-shaped structure formed by the bones of the pelvis. 2017-03-31 CDISC-1348 Update C12767 CDISC Synonym SPEC Specimen Remove CDISC Synonym Pelvic Cavity - - - 2017-03-31 CDISC-2710 Update C12768 CDISC Synonym SPEC Specimen Remove CDISC Synonym Peripheral Nerve - - - 2017-03-31 CDISC-1348 Update C12769 CDISC Definition SPEC Specimen Update CDISC Definition The lower part of the abdomen that contains the intestines (the last part of the digestive tract), the stomach, and the liver. It is bound by thin membranes. (NCI) A part of the abdominal cavity that lies between the visceral and parietal peritoneum. 2017-03-31 CDISC-1348 Update C12769 CDISC Synonym SPEC Specimen Remove CDISC Synonym Peritoneal Cavity - - - 2017-03-31 CDISC-1741 Update C12770 CDISC Definition SPEC Specimen Update CDISC Definition The tissue that lines the wall of the abdominal cavity, intestine, and mesentery. It consists of the parietal peritoneum that covers the inside of the abdominal wall and the visceral peritoneum that covers the surface of the intestine and mesentery. (NCI) The membrane that lines the abdominal and pelvic cavities. 2017-03-31 CDISC-1741 Update C12770 CDISC Synonym SPEC Specimen Remove CDISC Synonym Peritoneum - - - 2017-03-31 CDISC-1741; CDISC-2490 Update C12771 CDISC Definition SPEC Specimen Update CDISC Definition Lymphoid tissue on the mucosa of the small intestine. (MeSH) (NCI) An organized aggregate of gut-associated lymphoid tissue located in the mucosa of the small intestine. 2017-03-31 CDISC-2710 Update C12774 CDISC Definition SPEC Specimen Update CDISC Definition Either one of two arteries arising from the pulmonary trunk that carry deoxygenated blood to the lungs. One of the arteries of the thorax; in general it arises from the pulmonary trunk and branches into the lungs. 2017-03-31 CDISC-2331 Update C12775 CDISC Definition SPEC Specimen Update CDISC Definition A valve that is located between and controls the flow of blood from the right ventricle of the heart and the pulmonary artery. (NCI) A cardiac valve located between the right atrium and the pulmonary artery. 2017-03-31 CDISC-2331 Update C12776 CDISC Definition SPEC Specimen Update CDISC Definition One of four veins that carries oxygen-rich blood from the lungs to the cardiac left atrium. (NCI) Any of the veins that carry oxygenated blood from the lungs and drain into the left atrium of the heart. 2017-03-31 CDISC-1348 Update C12777 CDISC Definition SPEC Specimen Update CDISC Definition The long bone that extends from the lateral aspect of the elbow to the medial side of the carpus. The long bone that lies between the radiohumeral joint and the carpus and is adjacent to the ulna. 2017-03-31 CDISC-1348 Update C12777 CDISC Synonym SPEC Specimen Remove CDISC Synonym Radius - - - 2017-03-31 CDISC-1348 Update C12777 CDISC Synonym SPEC Specimen Remove CDISC Synonym Radius Bone - - - 2017-03-31 CDISC-2710 Update C12778 CDISC Definition SPEC Specimen Update CDISC Definition Either of two arteries (right or left) that arise from the aorta to supply the kidneys. One of the arteries of the abdomen; in general it arises from the abdominal aorta and supplies blood to the kidney. 2017-03-31 CDISC-1348 Update C12783 CDISC Definition SPEC Specimen Update CDISC Definition The flat triangle-shaped bone that connects the humerus with the clavicle in the back of the shoulder. (NCI) A bone that articulates with the humerus and is part of the scapulohumeral joint. 2017-03-31 CDISC-1348 Update C12783 CDISC Synonym SPEC Specimen Remove CDISC Synonym Scapula - - - 2017-03-31 CDISC-1543 Update C12784 CDISC Definition SPEC Specimen Update CDISC Definition The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. (From Cline et al., Dictionary of Visual Science, 4th ed) The fibrous, outer tunic of the eyeball that is continuous with the cornea. 2017-03-31 CDISC-1741 Update C12785 CDISC Definition SPEC Specimen Update CDISC Definition The musculocutaneous pouch that encloses the testicles. (NCI) The pouch that encloses the testicles. 2017-03-31 CDISC-1741 Update C12785 CDISC Synonym SPEC Specimen Remove CDISC Synonym Scrotum - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12787 CDISC Definition SPEC Specimen Update CDISC Definition One of the two paired glands in the male genitourinary system, posterior to the bladder and superior to the prostate gland, that produces fructose-rich seminal fluid which is a component of semen. These glands join the ipsilateral ductus deferens to form the ejaculatory duct. (NCI) A mammalian male reproductive accessory gland located adjacent to the urinary bladder and proximal to the prostate. 2017-03-31 CDISC-2710 Update C12792 CDISC Definition SPEC Specimen Update CDISC Definition Paired nerves that arise from the spinal cord. A nerve arising from the spinal cord where the dorsal and ventral roots converge and exit through the intervertebral foramen. 2017-03-31 CDISC-1348 Update C12793 CDISC Definition SPEC Specimen Update CDISC Definition The long, flat bone connecting with the cartilages of the first seven ribs and the clavicle. (NCI) The long, flat bone or sternebrae connecting with the cartilage of some ribs. 2017-03-31 CDISC-1348 Update C12793 CDISC Synonym SPEC Specimen Remove CDISC Synonym Sternum - - - 2017-03-31 CDISC-1348 Update C12796 CDISC Definition SPEC Specimen Update CDISC Definition Any one of the seven bones forming the instep of the foot. (NCI) Any of the short bones between the tibiotarsal joint and the tarsometatarsal joint. 2017-03-31 CDISC-1348 Update C12796 CDISC Synonym SPEC Specimen Remove CDISC Synonym Tarsus - - - 2017-03-31 CDISC-1348 Update C12796 CDISC Synonym SPEC Specimen Remove CDISC Synonym Tarsus Bone - - - 2017-03-31 CDISC-1348 Update C12800 CDISC Definition SPEC Specimen Update CDISC Definition A bone located between the femur and the tarsus, being part of the lower leg. (NCI) The long bone that is medial to the fibula. 2017-03-31 CDISC-1348 Update C12800 CDISC Synonym SPEC Specimen Remove CDISC Synonym Tibia - - - 2017-03-31 CDISC-2331 Remove C12801 Term SPEC Specimen Remove term entirely from codelist TISSUE - - - Retire existing term and replace with a new concept TISSUE, UNSPECIFIED (C132256). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-2363; CDISC-2331 Add C12802 Term SPEC Specimen Add new term to existing codelist - - - TONSIL Replaces TONSIL (C38516), which has been retired from this codelist. 2017-03-31 CDISC-2331 Update C12805 CDISC Submission Value SPEC Specimen Update CDISC Submission Value VALVE, TRICUSPID VALVE, RIGHT ATRIOVENTRICULAR 2017-03-31 CDISC-2331 Update C12805 CDISC Definition SPEC Specimen Update CDISC Definition A three-cusp valve of the heart that regulates the flow of blood between the right atrium and the right ventricle of the heart. (NCI) A cardiac valve located between the right atrium and ventricle. 2017-03-31 CDISC-2331 Update C12805 CDISC Synonym SPEC Specimen Add new CDISC Synonym - - - Tricuspid Valve 2017-03-31 CDISC-1741 Update C12806 CDISC Definition SPEC Specimen Update CDISC Definition The fifth set of paired nerves of the face that emerge from the brain steam. These nerves have sensory and motor functions in the face, oral cavity, and nasal cavity. (NCI) A cranial nerve extending from the pons, which innervates the skin, mucous membranes, and masticatory muscles of the head. 2017-03-31 CDISC-1741 Update C12806 CDISC Synonym SPEC Specimen Remove CDISC Synonym Nervus Trigeminus - - - 2017-03-31 CDISC-1741 Update C12806 CDISC Synonym SPEC Specimen Remove CDISC Synonym Trigeminal Nerve - - - 2017-03-31 CDISC-1348 Update C12809 CDISC Definition SPEC Specimen Update CDISC Definition The long bone that extends from the elbow to the lateral side of the carpus. The bone that contains the olecranon process, lies between the radiohumeral joint and the carpus, and is adjacent to the radius. 2017-03-31 CDISC-1348 Update C12809 CDISC Synonym SPEC Specimen Remove CDISC Synonym Ulna Bone - - - 2017-03-31 CDISC-1741 Update C12812 CDISC Definition SPEC Specimen Update CDISC Definition The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx). (MSH2001) A cranial nerve arising from the medulla oblongata, which provides efferent parasympathetic innervation to tissues and viscera in the neck, thorax and abdomen; it also includes somatic and visceral afferent nerve fibers. 2017-03-31 CDISC-1741 Update C12812 CDISC Synonym SPEC Specimen Add new CDISC Synonym - - - Tenth Cranial Nerve 2017-03-31 CDISC-2331 Update C12817 CDISC Definition SPEC Specimen Update CDISC Definition A large vein which returns blood from the head, neck and extremities to the heart. (NCI) The two major veins (caudal or cranial) that carry deoxygenated blood from the body and drain into the right atrium of the heart. 2017-03-31 CDISC-2331 Update C12817 CDISC Synonym SPEC Specimen Remove CDISC Synonym Vena Cava - - - 2017-03-31 CDISC-1348 Update C12837 CDISC Submission Value SPEC Specimen Update CDISC Submission Value COCHLEAR NUCLEI BRAIN, COCHLEAR NUCLEI 2017-03-31 CDISC-1348 Update C12837 CDISC Definition SPEC Specimen Update CDISC Definition Located at the brainstem, this sensory organ receives auditory signals from the cochlear auditory nerve fibers. It is composed of the dorsal cochlear nucleus located on the dorsolateral surface of the inferior peduncle and the ventral (or accessory) cochlear nucleus located on the ventral aspect of the inferior peduncle. (NCI) A collection of nuclei in the brainstem at which the auditory nerves terminate. 2017-03-31 CDISC-1348 Update C12840 CDISC Definition SPEC Specimen Update CDISC Definition The cavity lined by the pleura, located in the thorax and contains heart and lungs. (NCI) A part of the thoracic cavity that lies between the visceral and parietal pleura. 2017-03-31 CDISC-1348 Update C12840 CDISC Synonym SPEC Specimen Remove CDISC Synonym Pleural Cavity - - - 2017-03-31 CDISC-1348 Update C12843 CDISC Definition SPEC Specimen Update CDISC Definition A principal artery that originates in the aorta. It supplies blood to the muscular tissue of the heart. (NCI) One of the arteries of the heart; in general it arises from the aortic root and supplies the myocardium. 2017-03-31 CDISC-1348 Update C12843 CDISC Synonym SPEC Specimen Remove CDISC Synonym Coronary Artery - - - 2017-03-31 CDISC-2331 Update C12883 CDISC Definition SPEC Specimen Update CDISC Definition Deep vein of the upper arm that forms at the junction of the radial and ulnar veins and ends at the inferior border of the teres major. (NCI) A vein of the arm/forelimb; in general it arises from the union of the radial and ulnar veins and drains into the axillary vein. 2017-03-31 CDISC-2331 Update C12892 CDISC Definition SPEC Specimen Update CDISC Definition The portion of the spinal cord located in the cervical region. (NCI) The segment of the spinal cord between the end of the brain stem and the thoracic spinal cord. 2017-03-31 CDISC-2331 Update C12894 CDISC Definition SPEC Specimen Update CDISC Definition The portion of the spinal cord located in the thoracic region. (NCI) The segment of the spinal cord between the cervical spinal cord and the lumbar spinal cord. 2017-03-31 CDISC-2331 Update C12895 CDISC Definition SPEC Specimen Update CDISC Definition The portion of the spinal cord located in the lumbar region. (NCI) The segment of the spinal cord between the thoracic spinal cord and the sacral spinal cord. 2017-03-31 CDISC-2331 Update C12896 CDISC Definition SPEC Specimen Update CDISC Definition The portion of the spinal cord located in the sacral region. (NCI) The segment of the spinal cord between the lumbar spinal cord and the caudal spinal cord. 2017-03-31 CDISC-1543 Update C12901 CDISC Definition SPEC Specimen Update CDISC Definition The part of the conjunctiva, a thin transparent mucous membrane, that covers the posterior surface of the eyelids. The part of the conjunctiva that covers the inner surface of the eyelid. 2017-03-31 CDISC-1543 Update C12902 CDISC Definition SPEC Specimen Update CDISC Definition The part of the conjunctiva, a thin transparent mucous membrane, that is loosely attached to the orbital septum and covers the anterior surface of the sclera. The part of the conjunctiva that covers the eyeball. 2017-03-31 CDISC-1670; CDISC-1699 Update C12904 CDISC Definition SPEC Specimen Update CDISC Definition One of approximately 20-30 lymph nodes in chain formation that traverse the concavity of the underarm to the clavicle. (NCI) Lymph node(s) in the axillary region. 2017-03-31 CDISC-1670; CDISC-1699 Update C12904 CDISC Synonym SPEC Specimen Remove CDISC Synonym Axillary Lymph Node - - - 2017-03-31 CDISC-1348 Update C12905 CDISC Definition SPEC Specimen Update CDISC Definition The cavity in the vertebrate body enclosed by the ribs between the diaphragm and the neck and containing the lungs and heart. (NCI) The cavity enclosed by the ribs between the diaphragm and the neck. 2017-03-31 CDISC-1348 Update C12905 CDISC Synonym SPEC Specimen Remove CDISC Synonym Thoracic Cavity - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C12936 CDISC Definition SPEC Specimen Update CDISC Definition Non-encapsulated accumulations of lymphoid tissue in the alimentary tract that form a secretory immune system containing cells committed to IgA or IgE synthesis; It includes Peyer's patches and the lymphoid tissue which is present throughout the gastrointestinal mucosa. (NCI) Lymphoid tissue located in the mucosa of the digestive tract. 2017-03-31 CDISC-1670; CDISC-1699 Update C12936 CDISC Synonym SPEC Specimen Add new CDISC Synonym - - - GALT 2017-03-31 CDISC-2331 Update C12998 CDISC Definition SPEC Specimen Update CDISC Definition A series of bones, muscles, tendons, and other tissues reaching from the base of the skull to the tailbone. The vertebral column forms the axis of the skeleton and encloses as well as protects the spinal cord and the fluid surrounding the spinal cord. (NCI) The series of vertebrae and other tissues extending from the skull to the last tailbone. 2017-03-31 CDISC-2331 Update C12998 CDISC Synonym SPEC Specimen Remove CDISC Synonym Spinal Column - - - 2017-03-31 CDISC-1741 Update C13005 CDISC Definition SPEC Specimen Update CDISC Definition A conical membranous sac filled with serous fluid in which the heart as well as the roots of the aorta and other large blood vessels are contained. (NCI) The membrane surrounding the heart and roots of the vessels at the base of the heart. 2017-03-31 CDISC-1741 Update C13005 CDISC Synonym SPEC Specimen Remove CDISC Synonym Pericardium - - - 2017-03-31 CDISC-2710 Update C13050 CDISC Definition SPEC Specimen Update CDISC Definition Striated muscles that are under voluntary control of the organism. They are connected at either or both ends to a bone and are utilized for locomotion and other movements. (NCI) Voluntary, striated muscle tissue predominantly associated with the skeleton. 2017-03-31 CDISC-2710 Update C13050 CDISC Synonym SPEC Specimen Remove CDISC Synonym Skeletal Muscle Tissue - - - 2017-03-31 CDISC-1741 Remove C13052 Term SPEC Specimen Remove term entirely from codelist NERVE - - - Retire existing term and replace with a new concept NERVE (C12466). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1348 Update C13070 CDISC Definition SPEC Specimen Update CDISC Definition The fleshy part of the face bounded by the eyes, nose, ear, and jaw line. (NCI) The soft tissue on the lateral aspects of the face, generally bounded by the eyes, nose, ear, and jaw line. 2017-03-31 CDISC-1543 Update C13071 CDISC Definition SPEC Specimen Update CDISC Definition The portion of the head containing the eyes, nose and mouth, cheeks and jaws. The portion of the head that contains the structures such as the eyes, nose, mouth, and jaws. 2017-03-31 CDISC-1543 Update C13071 CDISC Synonym SPEC Specimen Remove CDISC Synonym Facial - - - 2017-03-31 CDISC-1741 Update C13074 CDISC Definition SPEC Specimen Update CDISC Definition Muscles arising in the zygomatic arch that close the jaw. (MeSH) (NCI) A muscle extending from the zygomatic arch to the lateral surface of mandibular ramus; primary function is elevation of the mandible (closing of the mouth). 2017-03-31 CDISC-1348 Remove C13076 Term SPEC Specimen Remove term entirely from codelist BONE - - - Retire existing term and replace with a new concept BONE (C12366). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1348 Update C13192 CDISC Definition SPEC Specimen Update CDISC Definition Fluid composed of waste products, bile acids, salts, cholesterol, and electrolytes. It is secreted by the liver parenchyma and stored in the gallbladder. (NCI) Fluid composed of waste products, bile acids, salts, cholesterol, and electrolytes. It is produced by the liver and may be stored in the gallbladder (if present). 2017-03-31 CDISC-2331 Add C132256 Term SPEC Specimen Add new term to existing codelist - - - TISSUE, UNSPECIFIED Replaces TISSUE (C12801), which has been retired from this codelist. 2017-03-31 CDISC-1543 Remove C13233 Term SPEC Specimen Remove term entirely from codelist EXUDATE - - - This term is considered a morphology or finding and should not be used as a specimen. Please use the existing term FLUID or a more specific fluid (if known) instead. 2017-03-31 CDISC-1741 Update C13257 CDISC Definition SPEC Specimen Update CDISC Definition Milk produced by females for the purpose of feeding their young. (NCI) A liquid produced by the mammary gland. 2017-03-31 CDISC-1741 Update C13275 CDISC Definition SPEC Specimen Update CDISC Definition A clear liquid secreted into the mouth by the salivary glands and mucous glands of the mouth; moistens the mouth and starts the digestion of starches. (NCI) A clear liquid secreted by the salivary glands. 2017-03-31 CDISC-1741 Update C13277 CDISC Definition SPEC Specimen Update CDISC Definition The thick, whitish secretion of the male reproductive organs. It is composed of spermatozoa in their nutrient plasma, secretions from the prostate, seminal vesicles, and various other glands, epithelial cells, and minor constituents. (NCI) The fluid containing the spermatozoa, secreted by the testes and accessory reproductive glands of the male. 2017-03-31 CDISC-1741 Update C13277 CDISC Synonym SPEC Specimen Remove CDISC Synonym Seminal Plasma - - - 2017-03-31 CDISC-2331 Update C13283 CDISC Definition SPEC Specimen Update CDISC Definition The fluid that is excreted by the kidneys. It is stored in the bladder and discharged through the urethra. (NCI) The fluid produced by the kidneys. 2017-03-31 CDISC-1741 Update C13356 CDISC Definition SPEC Specimen Update CDISC Definition Plasma is the fluid (acellular) portion of the circulating blood, as distinguished from the serum that is the fluid portion of the blood obtained by removal of the fibrin clot and blood cells after coagulation. The fluid (acellular) portion of the circulating blood with retained clotting components. 2017-03-31 CDISC-1543 Update C17730 CDISC Definition SPEC Specimen Update CDISC Definition Any tissue from a fetus. (NCI) Any prenatal tissue that has developed past the embryonic stage. 2017-03-31 CDISC-1348 Update C25264 CDISC Definition SPEC Specimen Update CDISC Definition A ridge or ridge-like structure. The carina of trachea is part of the lowest tracheal cartilage which is placed between the orifices of the two bronchi. A ridge at the bifurcation of the trachea where the primary bronchi meet. 2017-03-31 CDISC-1348 Update C26470 CDISC Definition SPEC Specimen Update CDISC Definition The upper jawbone in vertebrates: it is fused to the cranium. (NCI) The upper jaw bone holding the upper teeth. 2017-03-31 CDISC-1348 Update C26470 CDISC Synonym SPEC Specimen Remove CDISC Synonym Maxilla - - - 2017-03-31 CDISC-1348 Update C28401 CDISC Definition SPEC Specimen Update CDISC Definition Anatomical structure located in the vertebral forebrain that receives neural input regarding odors that have been detected by cells within the nasal cavity. The axons of olfactory receptor cells extend into the olfactory bulb. (NCI) The portion of the vertebrate forebrain that lies behind the ethmoid bones; it begins the rhinencephalon. 2017-03-31 CDISC-1348 Update C28401 CDISC Synonym SPEC Specimen Remove CDISC Synonym Olfactory Bulb - - - 2017-03-31 CDISC-2331 Update C32043 CDISC Definition SPEC Specimen Update CDISC Definition The tendon that connects the heel bone to the calf muscles at the back of the lower leg. (NCI) The tendon that, in general, attaches the gastrocnemius muscle to the calcaneous bone in the tarsus. 2017-03-31 CDISC-2331 Update C32043 CDISC Synonym SPEC Specimen Remove CDISC Synonym Calcaneal Tendon - - - 2017-03-31 CDISC-1670; CDISC-1699 Remove C32051 Term SPEC Specimen Remove term entirely from codelist GLAND, ADRENAL - - - Retire existing term and replace with a new concept GLAND, ADRENAL (C12666). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1741 Update C32200 CDISC Definition SPEC Specimen Update CDISC Definition A muscle in the upper limb. Its action involves the rotation of the limb and the flexion of the humeralradial joint. A muscle of the proximal arm/forelimb, in general extending from the scapula to the radius and adjacent fascia; primary function is flexion of the elbow joint and, in some species, also functions in supination of the antebrachium. 2017-03-31 CDISC-1741 Update C32200 CDISC Synonym SPEC Specimen Remove CDISC Synonym Biceps - - - 2017-03-31 CDISC-2331 Update C32201 CDISC Definition SPEC Specimen Update CDISC Definition A tooth rostral to true molars and behind the canine when the latter are present. A tooth between the canine and molar. 2017-03-31 CDISC-2331 Update C32201 CDISC Synonym SPEC Specimen Remove CDISC Synonym Bicuspid Tooth - - - 2017-03-31 CDISC-2331 Update C32201 CDISC Synonym SPEC Specimen Remove CDISC Synonym Premolar - - - 2017-03-31 CDISC-2331 Update C32201 CDISC Synonym SPEC Specimen Remove CDISC Synonym Premolar Tooth - - - 2017-03-31 CDISC-2363; CDISC-2331 Remove C32209 Term SPEC Specimen Remove term entirely from codelist URINARY BLADDER - - - Retire existing term and replace with a new concept URINARY BLADDER (C12414). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-2363 Remove C32213 Term SPEC Specimen Remove term entirely from codelist VESSEL, BLOOD - - - Retire existing term and replace with a new concept VESSEL, BLOOD (C12679). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1670; CDISC-1699 Update C32232 CDISC Definition SPEC Specimen Update CDISC Definition Lymph node located in the bronchi. (NCI) Lymph node(s) adjacent to the bronchi. 2017-03-31 CDISC-1348 Update C32234 CDISC Definition SPEC Specimen Update CDISC Definition Lymphoid tissue located with the bronchi. Lymphoid tissue located in the mucosa of the bronchi. 2017-03-31 CDISC-1348 Update C32235 CDISC Definition SPEC Specimen Update CDISC Definition Brown-colored adipose tissue that contains numerous small droplets of lipids and high numbers of mitochondria as its primary function is to generate body heat. Brown-colored adipose tissue that contains numerous small droplets of lipids and high numbers of mitochondria. 2017-03-31 CDISC-1348 Update C32268 CDISC Definition SPEC Specimen Update CDISC Definition A type of connective tissue composed of chondrocytes and an extracellular matrix, composed of collagen, elastin, and ground substance. There are three types of cartilage; namely elastic, hyaline, and fibrocartilage. (NCI) A type of connective tissue composed of chondrocytes and an extracellular matrix. There are three types of cartilage; namely elastic, hyaline, and fibrocartilage. 2017-03-31 CDISC-2331 Update C32286 CDISC Definition SPEC Specimen Update CDISC Definition One of five superficial veins of the upper extremity, beginning at the radial aspect of the wrist area, wrapping around the forearm and emptying into the axillary vein. (NCI) A vein of the arm/forelimb; in general it arises from the dorsal venous network of the hand/forefoot and drains into the axillary vein. 2017-03-31 CDISC-2331 Update C32286 CDISC Synonym SPEC Specimen Remove CDISC Synonym Cephalic Vein - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C32298 CDISC Definition SPEC Specimen Update CDISC Definition Any of the lymph nodes located in the neck. (NCI) Lymph node(s) in the cervical region, or neck. 2017-03-31 CDISC-1670; CDISC-1699 Update C32298 CDISC Synonym SPEC Specimen Remove CDISC Synonym Cervical Lymph Node - - - 2017-03-31 CDISC-2710 Update C32356 CDISC Definition SPEC Specimen Update CDISC Definition The extrahepatic duct that connects the convergence of the left and right hepatic ducts into the common bile duct. A duct that conveys bile from the convergence of the left and right hepatic ducts to the common bile duct. 2017-03-31 CDISC-1670; CDISC-1699 Update C32395 CDISC Definition SPEC Specimen Update CDISC Definition Paired exocrine glands located at the base of the penis, positioned posterior and lateral to the urethra, that produce and secrete a clear viscous liquid that lubricates the urethra in preparation for the passage of sperm. (NCI) The exocrine glands of the male reproductive system located at the base of the penis. 2017-03-31 CDISC-1670; CDISC-1699 Update C32395 CDISC Synonym SPEC Specimen Remove CDISC Synonym Gland, Cowper's - - - 2017-03-31 CDISC-1543 Update C32421 CDISC Definition SPEC Specimen Update CDISC Definition A short duct attached to the gallbladder through which the bile from the gallbladder is secreted in the common bile duct. (NCI) A duct that conveys bile from the gallbladder to the common bile duct. 2017-03-31 CDISC-2710 Update C32492 CDISC Definition SPEC Specimen Update CDISC Definition A tube-like structure that connects the rete testis to the head of the epididymis. A duct or ducts that convey spermatozoa from the rete testis to the head of the epididymis. 2017-03-31 CDISC-1543 Update C32529 CDISC Definition SPEC Specimen Update CDISC Definition The round end of the long bones. (NCI) The end of long bones that lies adjacent to the metaphysis. 2017-03-31 CDISC-1543 Update C32529 CDISC Synonym SPEC Specimen Remove CDISC Synonym Epiphyseal Plate - - - 2017-03-31 CDISC-1543 Update C32529 CDISC Synonym SPEC Specimen Remove CDISC Synonym Growth Plate - - - 2017-03-31 CDISC-1543 Update C32529 CDISC Synonym SPEC Specimen Remove CDISC Synonym Junction, Bone-Cartilage - - - 2017-03-31 CDISC-1543 Remove C32543 Term SPEC Specimen Remove term entirely from codelist ESOPHAGUS - - - Retire existing term and replace with a new concept ESOPHAGUS (C12389). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1543 Update C32622 CDISC Definition SPEC Specimen Update CDISC Definition The structure found below the ankle joint required for locomotion. (NCI) The entire structure distal to the ankle joint/tarsus, which includes the metatarsus and digit(s). 2017-03-31 CDISC-1543 Update C32622 CDISC Synonym SPEC Specimen Remove CDISC Synonym Feet - - - 2017-03-31 CDISC-1543 Update C32622 CDISC Synonym SPEC Specimen Remove CDISC Synonym Foot - - - 2017-03-31 CDISC-2363 Remove C32664 Term SPEC Specimen Remove term entirely from codelist STOMACH - - - Retire existing term and replace with a new concept STOMACH (C12391). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1741 Update C32666 CDISC Definition SPEC Specimen Update CDISC Definition A large muscle in the back of the lower limb. Its action involves the flexion of the tarsis. A bipennate muscle extending from the femoral condyles to the calcaneus; primary function is the extension of the tarsal joint and flexion of the femorotibial joint. 2017-03-31 CDISC-1670; CDISC-1699 Update C32677 CDISC Synonym SPEC Specimen Remove CDISC Synonym Gingiva - - - 2017-03-31 CDISC-1670; CDISC-1699 Remove C32735 Term SPEC Specimen Remove term entirely from codelist LIVER - - - Retire existing term and replace with a new concept LIVER (C12392). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1670; CDISC-1699 Update C32761 CDISC Definition SPEC Specimen Update CDISC Definition One of the three lymph nodes of the pelvis: the superior gluteal, interior gluteal or sacral. (NCI) Lymph node(s) adjacent to the iliac vessels in the iliosacral region and cranial to the iliofemoral lymph node. 2017-03-31 CDISC-1670; CDISC-1699 Update C32761 CDISC Synonym SPEC Specimen Remove CDISC Synonym Iliac Lymph Node - - - 2017-03-31 CDISC-2331 Update C32769 CDISC Definition SPEC Specimen Update CDISC Definition One of the teeth in front of the canines in either jaw designed for cutting or gnawing. (NCI) A tooth between the canines in either jaw. 2017-03-31 CDISC-2331 Update C32769 CDISC Synonym SPEC Specimen Remove CDISC Synonym Incisor - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C32801 CDISC Definition SPEC Specimen Update CDISC Definition A superficial or deep lymph node located in the inguinal area. (NCI) Lymph node(s) in the inguinal region. 2017-03-31 CDISC-1670; CDISC-1699 Update C32801 CDISC Synonym SPEC Specimen Remove CDISC Synonym Inguinal Lymph Node - - - 2017-03-31 CDISC-2710 Update C32814 CDISC Definition SPEC Specimen Update CDISC Definition An artery arising from the aortic arch that divides into the right common carotid and right subclavian arteries. An artery of the mediastinum; in general it arises from the aortic arch and branches to form the right subclavian artery and one or both common carotid arteries. 2017-03-31 CDISC-1741 Update C32824 CDISC Definition SPEC Specimen Update CDISC Definition A muscle located between two ribs. (NCI) A group of muscles extending from one rib to the adjacent rib; primary function is movement of the thoracic wall during inspiration and expiration. 2017-03-31 CDISC-1670; CDISC-1699 Update C32853 CDISC Definition SPEC Specimen Update CDISC Definition Any of the lymph nodes of the breast located under the ribcage, near the sternum. (NCI) Lymph node(s) in or adjacent to the mammary gland. 2017-03-31 CDISC-1670; CDISC-1699 Update C32898 CDISC Submission Value SPEC Specimen Update CDISC Submission Value JOINT, KNEE JOINT, FEMOROTIBIAL 2017-03-31 CDISC-1670; CDISC-1699 Update C32898 CDISC Definition SPEC Specimen Update CDISC Definition A joint connecting the lower part of the femur with the upper part of the tibia. The lower part of the femur and the upper part of the tibia are attached to each other by ligaments. Other structures of the knee joint include the upper part of the fibula, located below and parallel to the tibia, and the patella which moves as the knee bends. (NCI) The joint connecting the lower part of the femur with the upper part of the tibia. 2017-03-31 CDISC-1670; CDISC-1699 Update C32898 CDISC Synonym SPEC Specimen Add new CDISC Synonym - - - Femorotibial Joint 2017-03-31 CDISC-1670; CDISC-1699 Update C32898 CDISC Synonym SPEC Specimen Add new CDISC Synonym - - - Joint, Stifle 2017-03-31 CDISC-1670; CDISC-1699 Remove C32931 Term SPEC Specimen Remove term entirely from codelist LARGE INTESTINE - - - Retire existing term and replace with a new concept LARGE INTESTINE (C12379). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-2710 Update C32984 CDISC Definition SPEC Specimen Update CDISC Definition A broad, thin muscle originating from the posterior side of the pubis body, spine of the ischium, and pelvic fascia between the pubis and ischium on either side of the pelvis. A group of muscles, in general extending from the inner surfaces of the ischium and pubis to the coccyx/coccygeal vertebrae; primary function is downward and lateral movement of the tail in tailed species, and to support the pelvic cavity. 2017-03-31 CDISC-2331 Update C32988 CDISC Definition SPEC Specimen Update CDISC Definition A mass of lymphoid tissue located at the base of the dorsal surface of the tongue. A tonsil in the mucosa at the root of the tongue. 2017-03-31 CDISC-1670; CDISC-1699 Remove C33024 Term SPEC Specimen Remove term entirely from codelist LUNG - - - Retire existing term and replace with a new concept LUNG (C12468). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1670; CDISC-1699 Remove C33034 Term SPEC Specimen Remove term entirely from codelist LYMPH NODE - - - Retire existing term and replace with a new concept LYMPH NODE (C12745). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-2331 Update C33038 CDISC Definition SPEC Specimen Update CDISC Definition A tubule that carries lymph throughout the body. (NCI) A thin-walled tubular structure through which the lymph circulates in the body. 2017-03-31 CDISC-2331 Update C33038 CDISC Synonym SPEC Specimen Remove CDISC Synonym Vessel, Lymph - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C33073 CDISC Definition SPEC Specimen Update CDISC Definition A lymph node located in the mediastinum. Mediastinal lymph nodes are arranged in three groups, one on the lateral, another on the medial, and a third on the anterior aspect of the vessels; the third group is, however, sometimes absent. (NCI) Lymph node(s) in the mediastinal region. 2017-03-31 CDISC-1670; CDISC-1699 Update C33073 CDISC Synonym SPEC Specimen Remove CDISC Synonym Mediastinal Lymph Node - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C33075 CDISC Definition SPEC Specimen Update CDISC Definition A sebaceous gland in the eyelid that produces a specific type of sebum. (NCI) A sebaceous gland in the eyelid that produces meibum. 2017-03-31 CDISC-1741 Update C33096 CDISC Definition SPEC Specimen Update CDISC Definition A crescent-shaped wedge of cartilaginous material that serves as a cushion in the knee, between the tuberosities of the femur and the tibia. There are two locations, the medial meniscus located on the inner aspect of the knee and the lateral which is located on the outer aspect. (NCI) Cartilaginous material that serves as a cushion between the tuberosities of the femur and the tibia. 2017-03-31 CDISC-1741 Update C33097 CDISC Definition SPEC Specimen Update CDISC Definition A semicircular meniscus located towards the outer aspect of the knee joint. (NCI) A meniscus located towards the outer aspect of the femorotibial joint. 2017-03-31 CDISC-1741 Update C33098 CDISC Definition SPEC Specimen Update CDISC Definition A semicircular meniscus located towards the inner aspect of the knee joint. (NCI) A meniscus located towards the inner aspect of the knee/stifle joint. 2017-03-31 CDISC-1741 Update C33103 CDISC Definition SPEC Specimen Update CDISC Definition A double layer of peritoneum that attaches to the back wall of the abdominal cavity and supports the small intestines. (NCI) A double layer of peritoneum that attaches to the wall of the abdominal cavity and supports the small intestines. 2017-03-31 CDISC-2331 Update C33136 CDISC Definition SPEC Specimen Update CDISC Definition A grinding tooth with a broad crown; located behind the premolars. (NCI) A tooth behind the premolars. 2017-03-31 CDISC-1741 Update C33150 CDISC Definition SPEC Specimen Update CDISC Definition A triangular muscle in the back, connected to the vertebral column, arm, and shoulder. Its action involves adduction, medial rotation, and extension of the arm. (NCI) A muscle of the back, in general extending from the thoracolumbar vertebrae and scapula to the proximal humerus; primary function is adduction, extension, and medial rotation of the shoulder joint. 2017-03-31 CDISC-1543 Update C33161 CDISC Definition SPEC Specimen Update CDISC Definition A tube-like structure that conveys tears from the lacrimal sac to the nasal cavity. (NCI) A duct that conveys tears from the eye to the nasal cavity. 2017-03-31 CDISC-1543 Update C33161 CDISC Synonym SPEC Specimen Remove CDISC Synonym Duct, Nasolac - - - 2017-03-31 CDISC-1543 Update C3319 CDISC Definition SPEC Specimen Update CDISC Definition Fluid collection within the pericardial sac, usually due to inflammation. (NCI) The fluid within the pericardial cavity. 2017-03-31 CDISC-1741 Update C33199 CDISC Definition SPEC Specimen Update CDISC Definition A group of six muscles that are responsible for moving the eye. (NCI) A group of muscles in the orbit extending from the posterior orbit to the eye and upper eyelid; primary function is the movement of the eye and retraction of the upper eyelid. 2017-03-31 CDISC-1741 Update C33205 CDISC Definition SPEC Specimen Update CDISC Definition The part of the nasal mucosa composed of neuroepithelial tissue and mucus-producing Bowman's glands. The mucus moistens the epithelium and helps dissolve odor-containing gases. (NCI) The mucosal membranes that line the nasal cavity. 2017-03-31 CDISC-1741 Update C33205 CDISC Synonym SPEC Specimen Remove CDISC Synonym Olfactory Mucosa - - - 2017-03-31 CDISC-1741 Update C33209 CDISC Definition SPEC Specimen Update CDISC Definition A fold of peritoneum originating at the stomach and supporting the viscera. (NCI) A double layer of peritoneum covering abdominal organs. 2017-03-31 CDISC-1741 Update C33209 CDISC Synonym SPEC Specimen Remove CDISC Synonym Omental Fat - - - 2017-03-31 CDISC-2710 Update C33250 CDISC Definition SPEC Specimen Update CDISC Definition Paired small tissue masses located on opposite sides of the oropharynx between the faucial pillars. A tonsil in the mucosa of the glossopalatine arch of the oropharynx. 2017-03-31 CDISC-1670; CDISC-1699 Remove C33270 Term SPEC Specimen Remove term entirely from codelist GLAND, PARATHYROID - - - Retire existing term and replace with a new concept GLAND, PARATHYROID (C12765). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1670; CDISC-1699 Update C33278 CDISC Definition SPEC Specimen Update CDISC Definition A lymph node located close to, on, or within the parotid gland. (NCI) Lymph node(s) in or adjacent to the parotid gland. 2017-03-31 CDISC-1348 Update C33282 CDISC Definition SPEC Specimen Update CDISC Definition A small flat triangular bone in front of the knee that articulates with the femur and protects the knee joint. (NCI) A small bone in front of the femorotibial joint that articulates with the femur. 2017-03-31 CDISC-1348 Update C33282 CDISC Synonym SPEC Specimen Remove CDISC Synonym Patella - - - 2017-03-31 CDISC-1741 Update C33286 CDISC Definition SPEC Specimen Update CDISC Definition Muscles of the upper chest. The term may refer to one of two muscles, the pectoralis major and pectoralis minor. The former is a thick muscle in the anterior portion of the chest. Its action involves flexion, medial rotation, and adduction of the humerus. The latter is a thin muscle located beneath the pectoralis major. Its action involves lowering the scapula and raising the ribs. (NCI) A group of muscles on the exterior of the thorax, in general extending from the sternum to the humerus; primary function is movement of the upper forelimb. 2017-03-31 CDISC-1741 Update C33286 CDISC Synonym SPEC Specimen Remove CDISC Synonym Muscle, Pectoral - - - 2017-03-31 CDISC-1348 Update C33287 CDISC Definition SPEC Specimen Update CDISC Definition The caudal portion of the trunk, bounded anteriorly and laterally by the two hip bones incorporating the socket portion of the hip joint for each leg. Posteriorly it is bounded by the sacrum and coccyx. (NCI) The bony structure composed of the ilium, ishium, pubis and sacrum, which are typically fused during maturation. 2017-03-31 CDISC-1348 Update C33287 CDISC Synonym SPEC Specimen Remove CDISC Synonym Pelvis Bone - - - 2017-03-31 CDISC-2331 Update C33318 CDISC Definition SPEC Specimen Update CDISC Definition A fold of lymphatic tissue covered by ciliated epithelium at the very back of the nose, in the roof of the nasopharynx. (NCI) A tonsil in the mucosa of the nasopharynx. 2017-03-31 CDISC-2331 Update C33318 CDISC Synonym SPEC Specimen Remove CDISC Synonym Pharyngeal Tonsil - - - 2017-03-31 CDISC-2331 Update C33343 CDISC Definition SPEC Specimen Update CDISC Definition A short thick trunk vein that transports blood containing the absorbed products of digestion from the intestine directly to the liver. (NCI) A vein lying in the lower part of the abdomen; in general it arises from the junction of the mesenteric and splenic veins and draining into the liver. 2017-03-31 CDISC-2331 Update C33343 CDISC Synonym SPEC Specimen Remove CDISC Synonym Portal Vein - - - 2017-03-31 CDISC-1670; CDISC-1699 Remove C33414 Term SPEC Specimen Remove term entirely from codelist GLAND, PROSTATE - - - Retire existing term and replace with a new concept GLAND, PROSTATE (C12410). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1741 Update C33422 CDISC Definition SPEC Specimen Update CDISC Definition Muscles of the lower back whose actions involve the flexion of the hips and lumbar spine. The term may refer to psoas major muscle and psoas minor muscle, both located in the lower back. (NCI) A group of muscles on the abdominal spine, in general extending from the lumbar vertebrae to the femur; the primary function is flexion of the hip joint. 2017-03-31 CDISC-1741 Update C33441 CDISC Definition SPEC Specimen Update CDISC Definition A group of four powerful muscles in the front of the thigh. Their actions involve the extension of the knee joint. (NCI) A group of muscles in the thigh, in general extending from the pelvis to the patella and tibia; primary function is extension of the femorotibial joint. 2017-03-31 CDISC-1741 Update C33441 CDISC Synonym SPEC Specimen Remove CDISC Synonym Muscle, Quadriceps - - - 2017-03-31 CDISC-1741 Update C33441 CDISC Synonym SPEC Specimen Remove CDISC Synonym Muscle, Thigh - - - 2017-03-31 CDISC-1670; CDISC-1699 Remove C33461 Term SPEC Specimen Remove term entirely from codelist KIDNEY - - - Retire existing term and replace with a new concept KIDNEY (C12415). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-2710 Update C33462 CDISC Definition SPEC Specimen Update CDISC Definition The veins which return blood from the kidneys to the vena cava. (NCI) A vein arising from the kidney; in general it drains into the caudal vena cava vein. 2017-03-31 CDISC-1670; CDISC-1699 Remove C33509 Term SPEC Specimen Remove term entirely from codelist GLAND, SALIVARY - - - Retire existing term and replace with a new concept GLAND, SALIVARY (C12426). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-2331 Update C33511 CDISC Definition SPEC Specimen Update CDISC Definition One of two (Greater, Small) superficial veins of the leg and thigh. (NCI) A vein of the leg/hindlimb; in general it arises from the venous network of the leg/hindfoot and drains into the femoral vein. 2017-03-31 CDISC-1670; CDISC-1699 Update C33519 CDISC Definition SPEC Specimen Update CDISC Definition Small glands located within the epidermis, and associated with the hair follicle, that produce and secrete an oily substance that lubricates the skin and hair. (NCI) Small glands located within the skin that are usually associated with the hair follicle. 2017-03-31 CDISC-2363; CDISC-2331 Remove C33573 Term SPEC Specimen Remove term entirely from codelist SMALL INTESTINE - - - Retire existing term and replace with a new concept SMALL INTESTINE (C12386). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1348 Update C33587 CDISC Definition SPEC Specimen Update CDISC Definition A branch of the intercostal artery that supplies oxygenated blood to the spinal cord and the pia mater. (NCI) One of the arteries of the spine; in general it arises from the vertebral artery and supplies blood to the spinal cord. 2017-03-31 CDISC-2710 Update C33643 CDISC Definition SPEC Specimen Update CDISC Definition A paired artery located below the clavicle. The right subclavian artery originates from the brachiocephalic (innominate) artery and the left subclavian artery originates from the aortic arch. One of the arteries of the thorax; in general it arises from the brachiocephalic artery or the aortic arch and branches into several arteries to supply blood to the head, neck, and arm/forelimb. 2017-03-31 CDISC-2331 Update C33645 CDISC Definition SPEC Specimen Update CDISC Definition Adipose tissue located under the dermis. It binds underlying structures with the skin. The subcutis is important in the regulation of temperature of the skin itself and the body. The size of this layer varies throughout the body and from subject to subject. Adipose and connective tissue located deep to the dermis. 2017-03-31 CDISC-2331 Update C33645 CDISC Synonym SPEC Specimen Remove CDISC Synonym Subcutaneous Adipose Tissue - - - 2017-03-31 CDISC-1543 Update C33718 CDISC Definition SPEC Specimen Update CDISC Definition A viscid fluid secreted by the synovial membrane, serving as a lubricant. (NCI) The fluid within a joint capsule. 2017-03-31 CDISC-1543 Update C33718 CDISC Synonym SPEC Specimen Remove CDISC Synonym Synovial Fluid - - - 2017-03-31 CDISC-1348 Update C33732 CDISC Submission Value SPEC Specimen Update CDISC Submission Value CAUDA EPIDIDYMIS EPIDIDYMIS, CAUDA 2017-03-31 CDISC-1348 Update C33732 CDISC Definition SPEC Specimen Update CDISC Definition The lower part of the epididymis. (NCI) The region of the epididymis that connects to the vas deferens. 2017-03-31 CDISC-2331 Update C33739 CDISC Definition SPEC Specimen Update CDISC Definition A fluid containing oils, mucin, and proteins, which is secreted by the lacrimal gland and cleans and lubricates the eye. (NCI) The fluid secreted by the lacrimal apparatus. 2017-03-31 CDISC-1670; CDISC-1699 Remove C33785 Term SPEC Specimen Remove term entirely from codelist GLAND, THYROID - - - Retire existing term and replace with a new concept GLAND, THYROID (C12400). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-2363; CDISC-2331 Remove C33794 Term SPEC Specimen Remove term entirely from codelist TOOTH - - - Retire existing term and replace with a new concept TOOTH (C12506). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-2331 Update C33822 CDISC Definition SPEC Specimen Update CDISC Definition Serous membrane that covers the testicles. (NCI) The visceral and parietal serous membranes lining the testicular pouch. 2017-03-31 CDISC-1543 Update C33884 CDISC Definition SPEC Specimen Update CDISC Definition A clear, avascular, gelatinous body that occupies the posterior chamber of the eye. It is bounded by the retina except anteriorly where it lies adjacent to the lens and iris. The clear gelatinous material that occupies the space between the lens and the retina. 2017-03-31 CDISC-1348 Update C33889 CDISC Definition SPEC Specimen Update CDISC Definition Adipose tissue that collects, stores and releases fat in the form of triglycerides. It functions as a heat insulator, mechanical cushion and as a source of energy. White adipose tissue is composed of adipocytes that secrete leptin and other substances that effect energy homeostasis. Its distribution in the body is dependent on the sex of the individual. (NCI) White-colored adipose tissue that is predominantly composed of cells with a large single vacuole containing lipid. 2017-03-31 CDISC-2363; CDISC-2331 Remove C33952 Term SPEC Specimen Remove term entirely from codelist THYMUS - - - Retire existing term and replace with a new concept THYMUS (C12433). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-2363; CDISC-2331 Remove C34086 Term SPEC Specimen Remove term entirely from codelist SPLEEN - - - Retire existing term and replace with a new concept SPLEEN (C12432). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-2363; CDISC-2331 Remove C38516 Term SPEC Specimen Remove term entirely from codelist TONSIL - - - Retire existing term and replace with a new concept TONSIL (C12802). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1348 Update C38662 CDISC Definition SPEC Specimen Update CDISC Definition The potential body space formed between the parietal and visceral layers of the pericardial sac. (NCI) The body space between the epicardium and the pericardium. 2017-03-31 CDISC-1348 Update C38662 CDISC Synonym SPEC Specimen Remove CDISC Synonym Pericardial Cavity - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C41168 CDISC Definition SPEC Specimen Update CDISC Definition The tissue that contains hematopoietic cells and/or lymphocytes and immune system cells. Any of the tissues that contain hematopoietic cells and/or lymphocytes and immune system cells. 2017-03-31 CDISC-1670; CDISC-1699 Remove C41834 Term SPEC Specimen Remove term entirely from codelist GLAND, PINEAL - - - Retire existing term and replace with a new concept GLAND, PINEAL (C12398). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1670; CDISC-1699 Update C43362 CDISC Definition SPEC Specimen Update CDISC Definition The lower opening of the digestive tract, lying in the cleft between the buttocks, through which fecal matter is extruded. (NCI) The distal orifice of the digestive tract located between the rectum and the external surface of the body, comprising glandular, transitional, and squamous epithelium. 2017-03-31 CDISC-1670; CDISC-1699 Update C43362 CDISC Synonym SPEC Specimen Remove CDISC Synonym Anus - - - 2017-03-31 CDISC-1543 Remove C43615 Term SPEC Specimen Remove term entirely from codelist DUCT, BILE - - - Retire existing term and replace with a new concept DUCT, BILE (C12376). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1670; CDISC-1699 Update C49018 CDISC Definition SPEC Specimen Update CDISC Definition A lymph node that drains lymph from a region of interest. (NCI) Lymph node(s) that drains the lymph from a region of interest. 2017-03-31 CDISC-1670; CDISC-1699 Update C49018 CDISC Synonym SPEC Specimen Remove CDISC Synonym Regional Lymph Node - - - 2017-03-31 CDISC-1348 Remove C49136 Term SPEC Specimen Remove term entirely from codelist BRAIN, CEREBRUM - - - Retire existing term and replace with a new concept BRAIN, CEREBRUM (C12351). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1348 Remove C49137 Term SPEC Specimen Remove term entirely from codelist BRAIN, CEREBELLUM - - - Retire existing term and replace with a new concept BRAIN, CEREBELLUM (C12445). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1741 Remove C49269 Term SPEC Specimen Remove term entirely from codelist PENIS - - - Retire existing term and replace with a new concept PENIS (C12409). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1543 Update C49328 CDISC Definition SPEC Specimen Update CDISC Definition The tissue that constitutes the retina. It is composed of the following layers: ganglion cell layer, inner limiting membrane, inner nuclear layer, inner plexiform layer, layer of the ophthalmic nerve fibers, layer of the rods and cones, neural retina, outer limiting membrane, outer nuclear layer, outer plexiform layer, and retinal pigment epithelium. (NCI) The sensory tissue in the posterior portion of the eye that contains photoreceptors. 2017-03-31 CDISC-2363 Remove C49478 Term SPEC Specimen Remove term entirely from codelist INTESTINE - - - Retire existing term and replace with a new concept INTESTINE (C49478). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1741 Update C49594 CDISC Definition SPEC Specimen Update CDISC Definition One of three (Inferior, Middle, Superior) paired bony shelves located within the nasal cavity through which inhaled air is taken into the nasopharynx. It is lined with ciliated, pseudostratified columnar epithelium and functions to humidify, heat, and filter incoming air, as well as protecting the olfactory bulb and sinuses from incorrectly pressurized incoming air. (NCI) The bone that protrudes into the nasal cavity from the skull, variably covered by respiratory, transitional or olfactory epithelium. 2017-03-31 CDISC-1741 Update C52807 CDISC Definition SPEC Specimen Update CDISC Definition A nerve in the arm that runs along the inside of the upper arm down to the palm and little finger. A nerve arising from spinal nerves C8, T1 and T2, which innervates the flexor muscles of the arm/forelimb and skin of the arm/forelimb and lateral manus. 2017-03-31 CDISC-1741 Update C52809 CDISC Definition SPEC Specimen Update CDISC Definition One of two major branches of the sciatic nerve. It innervates the muscles of the lower limb and the muscles of the plantar aspect of the foot. A branch of the sciatic nerve that divides into the medial and lateral plantar nerves, and which innervates the muscles of the crus and the skin of the tarsus. 2017-03-31 CDISC-1741 Update C52810 CDISC Definition SPEC Specimen Update CDISC Definition The longest single nerve that is formed by the merging of the ventral rami of the L4, L5, and S1 in the pelvis and passes down the lower limb where it divides into the common peroneal and tibial nerves. (NCI) A nerve arising from the merge of the lumbar and sacral rami in the pelvis and dividing into the common peroneal and tibial nerves, and which innervates the muscles of the thigh. 2017-03-31 CDISC-1741 Update C52810 CDISC Synonym SPEC Specimen Remove CDISC Synonym Sciatic Nerve - - - 2017-03-31 CDISC-1741 Update C52812 CDISC Definition SPEC Specimen Update CDISC Definition A large nerve that arises from the brachial plexus and enervates the extensor muscles and skin of the entire upper limb's posterior aspect. (NCI) A nerve extending from the brachial plexus traveling the length of the arm/forelimb, which innervates the extensor muscles of the elbow, carpus and phalanges, as well as the skin on the dorsal aspect of the carpus, metacarpus and digits. 2017-03-31 CDISC-1741 Update C52814 CDISC Definition SPEC Specimen Update CDISC Definition Any one of the three (Common, Deep, and Superficial) peroneal nerves. A branch of the sciatic nerve that includes the common, deep, and/or superficial peroneal nerves, which innervates multiple muscles in the distal region of the leg/hindlimb. 2017-03-31 CDISC-1741 Update C52815 CDISC Definition SPEC Specimen Update CDISC Definition A branch of the brachial plexus that extends along the anterior aspect of the forearm and the hand. (NCI) A nerve extending from the brachial plexus traveling the length of the arm/thoracic limb, which innervates some flexor muscles of the arm/forelimb and the skin on the palmar aspect of the carpus, metacarpus and digits. 2017-03-31 CDISC-1348 Update C52849 CDISC Definition SPEC Specimen Update CDISC Definition An artery that supplies oxygenated blood to the ear. (NCI) One of the arteries of the pinna; in general it arises from the internal carotid artery or the superficial temporal artery. 2017-03-31 CDISC-2710 Update C52902 CDISC Definition SPEC Specimen Update CDISC Definition A group of three muscles (iliocostalis, longissimus, and spinalis) that are situated laterally to and covering the spinous processes of the vertebrae. A group of three paired epaxial muscle bundles (iliocostalis, longissimus, and spinalis) extending along and lateral to the spinous processes of the cervical, thoracic, and lumbar vertebrae; primary function is extension and rotation of the spine. 2017-03-31 CDISC-2710 Update C52918 CDISC Definition SPEC Specimen Update CDISC Definition Muscle located on the lateral part of the hindlimb. Its actions involve the extension of the digits and dorsiflexion of the foot. A muscle extending from the lateral surface of the tibia to the digits; primary function is the extension of the digits and flexion of the tarsal joint. 2017-03-31 CDISC-1348 Update C52941 CDISC Submission Value SPEC Specimen Update CDISC Submission Value ARTERY, MAMMARY ARTERY, INTERNAL THORACIC 2017-03-31 CDISC-1348 Update C52941 CDISC Definition SPEC Specimen Update CDISC Definition The blood vessel that supplies the breast and the anterior chest wall with arterial blood. It is located in the chest wall. (NCI) An artery of the thoracic wall; in general it arises from the subclavian artery and branches into the musculophrenic and superior epigastric arteries. 2017-03-31 CDISC-2710 Update C52975 CDISC Definition SPEC Specimen Update CDISC Definition A branch of the abdominal aorta that supplies blood to the intestines. (NCI) One of the arteries of the abdomen; in general it arises from the abdominal aorta and supplies blood mainly to the intestines. 2017-03-31 CDISC-1741 Update C53039 CDISC Definition SPEC Specimen Update CDISC Definition A group of muscles causing movement of the leg towards the midline of the body. (NCI) A group of muscles generally extending from the pubis to the femur; primary function is adduction of the thigh. 2017-03-31 CDISC-2331 Update C53055 CDISC Definition SPEC Specimen Update CDISC Definition One of two veins (inferior or superior) that returns deoxygenated blood from the intestines. (NCI) A vein of the abdomen; in general it arises from the intestines and pancreas, combines with the splenic vein, and drains into the portal vein. 2017-03-31 CDISC-2710 Update C53073 CDISC Definition SPEC Specimen Update CDISC Definition The largest muscle of the quadriceps femoris muscle group that extends laterally from the intertrochanteric line of the femur to the lateral aspects of the quadriceps femoris tendon and patella. A muscle in the quadriceps femoris muscle group lateral to the vastus intermedius; primary function is the extension of the femorotibial joint. 2017-03-31 CDISC-1741 Update C53075 CDISC Definition SPEC Specimen Update CDISC Definition A muscle located in the back of the lower leg beneath the gastrocnemius muscle. Its actions involve the flexion of the ankle joint and standing. (NCI) A muscle in the crus, in general extending from the tibia and fibula to the calcaneous; primary function is plantarflexion of the foot. 2017-03-31 CDISC-1741 Update C53079 CDISC Definition SPEC Specimen Update CDISC Definition An extensor muscle in the anterior surface of the tibia. (NCI) A muscle of the crus, in general extending from the tibia to the first metatarsal; primary function is rotation of the foot. 2017-03-31 CDISC-1670; CDISC-1699 Update C53146 CDISC Definition SPEC Specimen Update CDISC Definition Lymph node located within the fat layer of the knee joint. (NCI) Lymph node(s) adjacent to the femorotibial joint. 2017-03-31 CDISC-1741 Update C53147 CDISC Definition SPEC Specimen Update CDISC Definition A muscle in the back of the thigh. Its action involves the knee flexion and hip extension. (NCI) A muscle in the thigh, in general extending from the ischial tuberosity and posterior femur to the fibula; primary function is to extend the femorotibial joint. 2017-03-31 CDISC-1741 Update C53175 CDISC Definition SPEC Specimen Update CDISC Definition One of the four quadriceps muscles, located in the middle of the front of the thigh. Its actions involve the extension of the knee joint and flexion of the hip. (NCI) A muscle in the quadriceps femoris muscle group between the vastus lateralis and vastus medialis and lying on the vastus intermedius; primary function is extension of the femorotibilal joint. 2017-03-31 CDISC-1741 Update C53176 CDISC Definition SPEC Specimen Update CDISC Definition A muscle located at the posterior and medial aspect of the thigh that extends the hip joint, flexes the knee joint and assists in medially rotating the knee. A muscle of the thigh, in general extends from the ishium to the medial tibia; primary function is the extension of the hip. 2017-03-31 CDISC-1670; CDISC-1699 Update C62642 CDISC Definition SPEC Specimen Update CDISC Definition Large sensory ganglion of the trigeminal nerve that lies adjacent to the cavernous sinus in the trigeminal cavity of the dura mater. (NCI) Large sensory ganglion of the trigeminal nerve. 2017-03-31 CDISC-1348 Update C66852 CDISC Definition SPEC Specimen Update CDISC Definition A cluster of cells that function as chemo-receptors, located at the bifurcation of the carotid artery. Its main purpose is to detect changes in the composition of arterial blood. (NCI) A cluster of cells that function as chemo-receptors, located near the bifurcation of the carotid artery. 2017-03-31 CDISC-1348 Update C70699 CDISC Definition SPEC Specimen Update CDISC Definition Any material sample taken from a biological entity for testing, diagnostic, propagation, treatment or research purposes, including a sample obtained from a living organism or taken from the biological object after halting of all its life functions. Biospecimen can contain one or more components including but not limited to cellular molecules, cells, tissues, organs, body fluids, embryos, and body excretory products. (NCI) Any material sample taken from a biological entity for testing, diagnostic, propagation, treatment or research purposes. 2017-03-31 CDISC-1348 Update C77608 CDISC Definition SPEC Specimen Update CDISC Definition The tissues that surround the organs that are present within the abdominal cavity. The abdominal wall tissue is composed of layers of fat, parietal peritoneum, fascia, and muscles. (NCI) The tissue that surrounds the organs present in the abdominal cavity. 2017-03-31 CDISC-1670; CDISC-1699 Update C77610 CDISC Definition SPEC Specimen Update CDISC Definition A large apocrine gland located in the area surrounding the anal orifice. (NCI) Superficial sebaceous glands located around the anus and contain fat. (Textbook of Small Animal Surgery - Volume 1. Slatter D (Ed.) (2003) Elsevier Health Sciences, Philadelpha PA) 2017-03-31 CDISC-1543 Update C77611 CDISC Definition SPEC Specimen Update CDISC Definition The fluid that is abnormally collected in the abdominal cavity as a result of vascular pressure, liver disorder, or malignancy. (NCI) The fluid within the abdomen, which may contain peritoneal or other fluids. 2017-03-31 CDISC-2710 Update C77612 CDISC Definition SPEC Specimen Update CDISC Definition The small amount of fluid that is generated in the abdominal cavity to lubricate the peritoneum. (NCI) The fluid produced by the peritoneum. 2017-03-31 CDISC-2710 Update C77612 CDISC Synonym SPEC Specimen Remove CDISC Synonym Fluid, Ascites - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C77614 CDISC Synonym SPEC Specimen Add new CDISC Synonym - - - Stomach Contents 2017-03-31 CDISC-1670; CDISC-1699 Update C77614 CDISC Synonym SPEC Specimen Remove CDISC Synonym Digestive Contents - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C77614 CDISC Synonym SPEC Specimen Remove CDISC Synonym Ingesta - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C77616 CDISC Definition SPEC Specimen Update CDISC Definition A gland producing tears in a third eyelid in the corner of each eye, as seen in animals. (NCI) A gland producing tears in a third eyelid. 2017-03-31 CDISC-1670; CDISC-1699 Update C77617 CDISC Definition SPEC Specimen Update CDISC Definition A female reproductive gland located on the side of the clitoris. (NCI) Exocrine gland of the female reproductive system located under the skin adjacent to the vulva. 2017-03-31 CDISC-1670; CDISC-1699 Update C77618 CDISC Definition SPEC Specimen Update CDISC Definition The anterior lobe of the prostate gland in animals. (NCI) The portion of the prostate, which when present, is adjacent to the seminal vesicles. 2017-03-31 CDISC-1670; CDISC-1699 Update C77619 CDISC Definition SPEC Specimen Update CDISC Definition An accessory gland of the orbit. (NCI) The accessory sebaceous glands of the orbit. 2017-03-31 CDISC-1670; CDISC-1699 Update C77620 CDISC Definition SPEC Specimen Update CDISC Definition A gland located in the area around the anus. (NCI) Deep sebaceous glands located around the anus and contain no fat. (Textbook of Small Animal Surgery - Volume 1. Slatter D (Ed.) (2003) Elsevier Health Sciences, Philadelpha PA) 2017-03-31 CDISC-1670; CDISC-1699 Update C77622 CDISC Definition SPEC Specimen Update CDISC Definition The dorsolateral lobe of the prostate gland in animals. (NCI) A lobe of the prostate gland located on the dorsolateral aspect of the proximal urethra. 2017-03-31 CDISC-1670; CDISC-1699 Update C77623 CDISC Definition SPEC Specimen Update CDISC Definition The ventral lobe of the prostate gland in animals. (NCI) A lobe of the prostate gland located on the ventral aspect of the proximal urethra. 2017-03-31 CDISC-1670; CDISC-1699 Update C77624 CDISC Definition SPEC Specimen Update CDISC Definition A salivary gland located in the upper portion of the mouth. (NCI) The salivary gland located adjacent to the zygomatic arch. 2017-03-31 CDISC-1741 Update C77637 CDISC Definition SPEC Specimen Update CDISC Definition Moist tissue lining the oral cavity, containing mucus secreting glands. The mucosal membranes that line the oral cavity. 2017-03-31 CDISC-1670; CDISC-1699 Update C77640 CDISC Definition SPEC Specimen Update CDISC Definition Any of the lymph nodes adjacent to the stomach and duodenum. (NCI) Lymph node(s) adjacent to the liver. 2017-03-31 CDISC-1670; CDISC-1699 Update C77641 CDISC Definition SPEC Specimen Update CDISC Definition A lymph node located in the mesentery. (NCI) Lymph node(s) in or adjacent to the mesentery. 2017-03-31 CDISC-1670; CDISC-1699 Update C77642 CDISC Definition SPEC Specimen Update CDISC Definition A lymph node of the pancreas. (NCI) Lymph node(s) in or adjacent to the pancreas. 2017-03-31 CDISC-1670; CDISC-1699 Update C77643 CDISC Definition SPEC Specimen Update CDISC Definition A lymph node located adjacent to the lumbar region of the spine. (NCI) Lymph node(s) adjacent to the lumbar vertebral column. 2017-03-31 CDISC-1670; CDISC-1699 Update C77645 CDISC Definition SPEC Specimen Update CDISC Definition Lymph nodes surrounding the portal vein. (NCI) Lymph node(s) adjacent to the portal vein. 2017-03-31 CDISC-1670; CDISC-1699 Update C77646 CDISC Definition SPEC Specimen Update CDISC Definition A lymph node located in the hilar area of the kidney or the fat surrounding the kidney. (NCI) Lymph node(s) adjacent to the hilar region of the kidney. 2017-03-31 CDISC-1670; CDISC-1699 Update C77647 CDISC Definition SPEC Specimen Update CDISC Definition A lymph node located in the sacral region. (NCI) Lymph node(s) in the sacral region. 2017-03-31 CDISC-1670; CDISC-1699 Update C77650 CDISC Definition SPEC Specimen Update CDISC Definition A lymph node located beneath the floor of the oral cavity. (NCI) Lymph node(s) adjacent to the mandible. 2017-03-31 CDISC-1670; CDISC-1699 Update C77651 CDISC Definition SPEC Specimen Update CDISC Definition A lymph node located near the bifurcation of the trachea. (NCI) Lymph node(s) adjacent to the bifurcation of the trachea. 2017-03-31 CDISC-1670; CDISC-1699 Update C77652 CDISC Definition SPEC Specimen Update CDISC Definition A lymph node located in the intercostal space of the thoracic wall. (NCI) Lymph node(s) in the intercostal space. 2017-03-31 CDISC-1670; CDISC-1699 Update C77653 CDISC Definition SPEC Specimen Update CDISC Definition A lymph node at the ileocecocolic junction. (NCI) Lymph node(s) adjacent to the ileocecocolic junction. 2017-03-31 CDISC-1670; CDISC-1699 Update C77654 CDISC Submission Value SPEC Specimen Update CDISC Submission Value LYMPH NODE, PRESCAPULAR LYMPH NODE, CERVICAL, SUPERFICIAL 2017-03-31 CDISC-1670; CDISC-1699 Update C77654 CDISC Definition SPEC Specimen Update CDISC Definition A lymph node located in front of the shoulder. (NCI) Lymph node(s) in the side of the neck, cranial to the scapula and lateral to the deep cervical lymph node. 2017-03-31 CDISC-1670; CDISC-1699 Update C77654 CDISC Synonym SPEC Specimen Add new CDISC Synonym - - - Prescapular Lymph Node 2017-03-31 CDISC-1741 Update C77660 CDISC Definition SPEC Specimen Update CDISC Definition The foot of a quadruped animal, including canines, felines, mice, rats, and bears. The paw contains claws or nails and pads composed of a thick keratinized dermis covering collagenous adipose tissue. (NCI) The entire structure distal to the ankle joint/tarsus or wrist joint/carpus in quadruped animals, containing claws or nails and pads. 2017-03-31 CDISC-2331 Update C77661 CDISC Definition SPEC Specimen Update CDISC Definition The part of the stomach that is lined with glandular mucosa and receives the food from the esophagus. The mucosa contains gastric glands that secret gastric acid. (NCI) The portion of the stomach that contains glandular mucosa. 2017-03-31 CDISC-2331 Update C77662 CDISC Definition SPEC Specimen Update CDISC Definition The portion of the animal stomach that is responsible for storage and digestion of food particles but does not contain the gastric mucosa-associated glands. The portion of the stomach that contains stratified squamous mucosa. 2017-03-31 CDISC-2331; CDISC-2139 Update C77663 CDISC Definition SPEC Specimen Update CDISC Definition The flexible prolongated structure of the posterior part of an animal's body. (NCI) A flexible appendage distal to the sacrum. 2017-03-31 CDISC-2331 Update C77664 CDISC Definition SPEC Specimen Update CDISC Definition The outer projections from the mammary organ of an animal. They are the structures through which the milk is discharged. (NCI) A specialized type of nipple distinguished by its large cistern (lactiferous sinus) that connects to the exterior through the teat canal. 2017-03-31 CDISC-2331 Update C77665 CDISC Synonym SPEC Specimen Remove CDISC Synonym Carcass - - - 2017-03-31 CDISC-2331 Update C77666 CDISC Definition SPEC Specimen Update CDISC Definition Stomach contents that have returned to the mouth or are ejected beyond the mouth. (NCI) Partially digested gastric contents that are returned to the mouth or beyond via the vomit reflex present in some species. 2017-03-31 CDISC-2331 Update C77666 CDISC Synonym SPEC Specimen Add new CDISC Synonym - - - Vomitus 2017-03-31 CDISC-2331 Update C77666 CDISC Synonym SPEC Specimen Remove CDISC Synonym Vomit - - - 2017-03-31 CDISC-1670; CDISC-1699 Update C77667 CDISC Definition SPEC Specimen Update CDISC Definition A laboratory specimen consisting of the thyroid and parathyroid. (NCI) A specimen that contains the thyroid and parathyroid glands. 2017-03-31 CDISC-2363 Update C77668 CDISC Definition SPEC Specimen Update CDISC Definition A laboratory specimen consisting of the testis and epididymis. (NCI) A specimen that contains the testis and epididymis. 2017-03-31 CDISC-2363 Update C77669 CDISC Definition SPEC Specimen Update CDISC Definition A laboratory specimen consisting of the liver and gallbladder. (NCI) A specimen that contains the liver and gallbladder. 2017-03-31 CDISC-2363 Update C77670 CDISC Definition SPEC Specimen Update CDISC Definition A laboratory specimen consisting of the prostate and seminal vesicles. (NCI) A specimen that contains the prostate and seminal vesicles. 2017-03-31 CDISC-2363 Update C77672 CDISC Definition SPEC Specimen Update CDISC Definition A laboratory specimen consisting of the uterus and ovaries. (NCI) A specimen that contains the uterus and ovaries. 2017-03-31 CDISC-2331 Update C77673 CDISC Definition SPEC Specimen Update CDISC Definition A vein located in the ear region. It may pertain to the anterior or posterior auricular veins. (NCI) One of the veins of the pinna; in general these veins anastmose with each other or drain into the internal maxillary or superficial temporal vein. 2017-03-31 CDISC-1741 Update C77674 CDISC Definition SPEC Specimen Update CDISC Definition A nerve that innervates the sole of the foot. This term may refer to the medial plantar nerve or lateral plantar nerve, both of which originate from the tibial nerve. (NCI) A nerve arising from the tibial nerve and dividing into the medial and lateral plantar nerves, which innervates the skin and muscles of the plantar region of the foot/hindfoot. 2017-03-31 CDISC-1741 Update C77675 CDISC Definition SPEC Specimen Update CDISC Definition A peripheral nerve that runs close to the small saphenous vein. It supplies innervation to the skin of the lower back of the leg and sends a branch to the lateral side of the foot and little toe. (NCI) A minor branch of the sciatic nerve that includes the lateral and caudal sural nerves, which innervates the skin of the crus, tarsus and metatarsus. 2017-03-31 CDISC-1670; CDISC-1699 Update C77954 CDISC Definition SPEC Specimen Update CDISC Definition A sebaceous gland located at the base of the rodent external ear that produces and secretes oil, which lubricates the auditory canal. (NCI) A sebaceous gland located at the base of the rodent external ear. 2017-03-31 CDISC-1670; CDISC-1699 Update C77955 CDISC Definition SPEC Specimen Update CDISC Definition Paired exocrine glands of the male reproductive system located at the medial termination of the ductus deferens that produce and secrete lipids and glycogen, components of the seminal fluid. (NCI) The exocrine glands of the male reproductive system located at the terminal portion of the ductus deferens. 2017-03-31 CDISC-1670; CDISC-1699 Update C77956 CDISC Definition SPEC Specimen Update CDISC Definition Non-glandular portion of the stomach of some mammals that is connected to the esophagus. It is utilized as a holding chamber during digestion for un-digested and partially digested food. (NCI) Non-glandular portion of the stomach of some mammals that is connected to the esophagus. 2017-03-31 CDISC-1741 Update C78205 CDISC Definition SPEC Specimen Update CDISC Definition Any of the skeletal muscles that form the buttocks. These muscles are responsible for hip abduction and extension as well as movement of the thigh. (NCI) A group of three muscles (gluteus maximus, gluteus medius, gluteus minimus) extending from the ilium and sacrum to the femur; primary function is extension and abduction of the hip joint. 2017-03-31 CDISC-1670; CDISC-1699 Update C79432 CDISC Definition SPEC Specimen Update CDISC Definition Exocrine glands located at the anterior aspect of the genitals of some mammals, such as mice and rats, that produce and secrete pheromones. (NCI) Exocrine glands of the male reproductive system located adjacent to the prepuce. 2017-03-31 CDISC-1741 Update C90604 CDISC Definition SPEC Specimen Update CDISC Definition The muscle of the upper limb that extends the limb. A muscle of the proximal arm/forelimb, in general extending from the scapula and humerus to the olecranon of the ulna; primary function is extension of humeroulnar joint. 2017-03-31 CDISC-1670; CDISC-1699 Update C92211 CDISC Definition SPEC Specimen Update CDISC Definition A sympathetic ganglion located at the seventh cervical vertebral level. (NCI) A sympathetic ganglion located near the junction of the cervical region and thorax. 2017-03-31 CDISC-1670; CDISC-1699 Update C92214 CDISC Definition SPEC Specimen Update CDISC Definition A tissue sample that contains the trigeminal ganglion and branches of the trigeminal nerve. (NCI) A specimen that contains the trigeminal ganglion and the trigeminal nerve. 2017-03-31 CDISC-1670; CDISC-1699 Update C92215 CDISC Definition SPEC Specimen Update CDISC Definition A tissue sample that contains the submandibular and sublingual salivary glands. (NCI) A specimen that contains the submandibular and sublingual salivary glands. 2017-03-31 CDISC-1670; CDISC-1699 Update C92216 CDISC Definition SPEC Specimen Update CDISC Definition A tissue sample that contains a seminal vesicle and coagulating gland. (NCI) A specimen that contains a seminal vesicle and coagulating gland. 2017-03-31 CDISC-1670; CDISC-1699 Update C92217 CDISC Definition SPEC Specimen Update CDISC Definition A tissue sample that contains the rectum and anus. (NCI) A specimen that contains the rectum and anus. 2017-03-31 CDISC-2363 Update C92218 CDISC Definition SPEC Specimen Update CDISC Definition A sample that contains lung and bronchial tissues. (NCI) A specimen that contains lung and bronchial tissues. 2017-03-31 CDISC-1670; CDISC-1699 Update C92221 CDISC Definition SPEC Specimen Update CDISC Definition An axillary lymph node along the brachial vein. (NCI) Lymph node(s) adjacent to the brachial vein. 2017-03-31 CDISC-1670; CDISC-1699 Update C92222 CDISC Definition SPEC Specimen Update CDISC Definition A lymph node along the left gastric artery or greater omentum. (NCI) Lymph node(s) adjacent to the stomach. 2017-03-31 CDISC-1670; CDISC-1699 Update C92434 CDISC Definition SPEC Specimen Update CDISC Definition A lymph node located under the tongue in the floor of the mouth. (NCI) Lymph node(s) adjacent to the tongue in the floor of the oral cavity. 2017-03-31 CDISC-1741 Update C92435 CDISC Definition SPEC Specimen Update CDISC Definition A tissue sample that contains mesenteric fat and peritoneal tissue. (NCI) A specimen that contains mesentery and peritoneum. 2017-03-31 CDISC-2363 Update C92436 CDISC Definition SPEC Specimen Update CDISC Definition A tissue sample that contains the body of uterus and the cervix. (NCI) A specimen that contains the uterus and cervix. 2017-03-31 CDISC-2363 Update C92441 CDISC Definition SPEC Specimen Update CDISC Definition A tissue sample that contains the epidermis, dermis, and subcutaneous adipose tissue. (NCI) A specimen that contains the epidermis, dermis, and subcutaneous adipose tissue. 2017-03-31 CDISC-1348 Update C92592 CDISC Definition SPEC Specimen Update CDISC Definition The location of the brain that corresponds to the narrowing of the fourth ventricle into the central canal of the spinal column. (NCI) The region of the medulla oblongata at which the fourth ventricle transitions into the central canal of the spinal cord. 2017-03-31 CDISC-1670; CDISC-1699 Update C92594 CDISC Definition SPEC Specimen Update CDISC Definition A lymph node located below the ilium. (NCI) Lymph node(s) in the inguinofemoral region. 2017-03-31 CDISC-2363 Update C92595 CDISC Definition SPEC Specimen Update CDISC Definition A laboratory specimen consisting of the ovaries and oviduct. (NCI) A specimen that contains the ovary and oviduct. 2017-03-31 CDISC-2331 Remove C92597 Term SPEC Specimen Remove term entirely from codelist SPINAL CORD, THORACOLUMBAR - - - No companies represented on SEND CT and SEND core teams currently use this term as a Specimen. Please use existing published terms SPINAL CORD, THORACIC or SPINAL CORD, LUMBAR or use Multiple convention or a combined term (codelist is extensible) using a slash. 2017-03-31 CDISC-2331 Update C92598 CDISC Definition SPEC Specimen Update CDISC Definition A vein located in the tail of vertebrate animals that leads to the inferior vena cava in mammals and the posterior cardinal vein in the trunk of fish. (NCI) A vein in the tail of some species. 2017-03-31 CDISC-2363 Remove C92600 Term SPEC Specimen Remove term entirely from codelist OROPHARYNX - - - Retire existing term and replace with a new concept OROPHARYNX (C12762). The SEND CT team has agreed that tissue-specific concepts are not appropriate for this codelist and so the coding change will bring the concepts in line with what was meant by the submission values. 2017-03-31 CDISC-1741 Update C92601 CDISC Definition SPEC Specimen Update CDISC Definition A terminal branch of the sciatic nerve. It innervates the calf and foot. The portion of the peroneal nerve that extends from the sciatic nerve to the bifurcation of the deep and superficial peroneal nerves. 2017-03-31 CDISC-1741 Update C92602 CDISC Definition SPEC Specimen Update CDISC Definition A branch of the common peroneal nerve. It innervates the ankle and toes. A branch of the common peroneal nerve that runs deep to the superficial peroneal nerve and which predominantly innervates the muscles of the crus and foot/hindfoot. 2017-03-31 CDISC-1741 Update C92603 CDISC Definition SPEC Specimen Update CDISC Definition A branch of the common peroneal nerve. It innervates the surface of the calf and foot. A branch of the common peroneal nerve that runs superficial to the deep peroneal nerve and which predominantly innervates the skin of the crus and foot/hindfoot. 2017-03-31 CDISC-1348 Update C98702 CDISC Definition SPEC Specimen Update CDISC Definition The glandular stomach of the ruminant. (NCI) The glandular stomach of ruminants. 2017-03-31 CDISC-1670; CDISC-1699 Update C98713 CDISC Definition SPEC Specimen Update CDISC Definition Any one of the three sympathetic ganglia of the cervical vertebrae. (NCI) Any of the sympathetic ganglia of the cervical vertebrae. 2017-03-31 CDISC-1274 Add C132489 Term STSPRM SEND Trial Summary Parameter Test Name Add new term to existing codelist - - - Contributing Scientist 2017-03-31 CDISC-1274 Add C132489 Term STSPRMCD SEND Trial Summary Parameter Test Code Add new term to existing codelist - - - CNTRBSC 2017-03-31 CDISC-2632 Add C132472 Term UNIT Unit Add new term to existing codelist - - - /200 HPFs 2017-03-31 CDISC-2632 Add C132473 Term UNIT Unit Add new term to existing codelist - - - /2000 RBC 2017-03-31 CDISC-2632 Add C132474 Term UNIT Unit Add new term to existing codelist - - - /2500 WBC 2017-03-31 CDISC-2632 Add C132475 Term UNIT Unit Add new term to existing codelist - - - /40 HPFs 2017-03-31 CDISC-2632 Add C132476 Term UNIT Unit Add new term to existing codelist - - - /500 WBC 2017-03-31 CDISC-2632 Add C132477 Term UNIT Unit Add new term to existing codelist - - - BP 2017-03-31 CDISC-2031 Add C132478 Term UNIT Unit Add new term to existing codelist - - - log10 TCID 50/mL 2017-03-31 CDISC-2031 Add C132479 Term UNIT Unit Add new term to existing codelist - - - log10 TCID 50/uL 2017-03-31 CDISC-1980 Add C132480 Term UNIT Unit Add new term to existing codelist - - - mMU/mL 2017-03-31 CDISC-2190 Add C132481 Term UNIT Unit Add new term to existing codelist - - - uL/kg/day 2017-03-31 CDISC-2650 Add C132482 Term VSTEST Vital Signs Test Name Add new term to existing codelist - - - Estimated Weight 2017-03-31 CDISC-2650 Add C132482 Term VSTESTCD Vital Signs Test Code Add new term to existing codelist - - - EWEIGHT