Release Date Request Code Change Type NCI Code CDISC Term Type CDISC Codelist (Short Name) CDISC Codelist (Long Name) Change Summary Original New Change Implementation Instructions 2016-03-25 CDISC-2393 Update C71115 CDISC Synonym EGMETHOD ECG Test Method Remove CDISC Synonym Standard leads for bicycle exercise. Limb leads on the back (shoulder and on the hips) - - - 2016-03-25 CDISC-2194 Update C2978 CDISC Synonym FXFINDRS Fetal Pathology Findings Result Remove CDISC Synonym Cysts - - - 2016-03-25 CDISC-2175 Update C100439 CDISC Definition LBTEST Laboratory Test Name Update CDISC Definition A measurement of the volume of serum or plasma that would be cleared of Iohexol through excretion for a specified unit of time. A measurement of the volume of serum or plasma that would be cleared of Iohexol by excretion of urine for a specified unit of time (e.g. one minute). 2016-03-25 CDISC-2175 Update C100440 CDISC Definition LBTEST Laboratory Test Name Update CDISC Definition A measurement of the volume of serum or plasma that would be cleared of Ethylenediamine tetraacetic acid (EDTA) through its excretion for a specified unit of time. A measurement of the volume of serum or plasma that would be cleared of Ethylenediamine tetraacetic acid (EDTA) by excretion of urine for a specified unit of time (e.g. one minute). 2016-03-25 CDISC-2175 Update C100441 CDISC Definition LBTEST Laboratory Test Name Update CDISC Definition A measurement of the volume of serum or plasma that would be cleared of Diethylenetriamine pentaacetate (DTPA) through its excretion for a specified unit of time. A measurement of the volume of serum or plasma that would be cleared of Diethylenetriamine pentaacetate (DTPA) by excretion of urine for a specified unit of time (e.g. one minute). 2016-03-25 CDISC-2267 Update C120652 CDISC Synonym LBTEST Laboratory Test Name Add new CDISC Synonym - - - Rheumatoid Factor IgA Antibody 2016-03-25 CDISC-2267 Update C120652 CDISC Synonym LBTEST Laboratory Test Name Remove CDISC Synonym Rheumatoid Factor Antibody IgA - - - 2016-03-25 CDISC-2267 Update C120652 CDISC Submission Value LBTEST Laboratory Test Name Update CDISC Submission Value Rheumatoid Factor Antibody IgA Rheumatoid Factor IgA Antibody 2016-03-25 CDISC-2268 Update C120653 CDISC Synonym LBTEST Laboratory Test Name Add new CDISC Synonym - - - Rheumatoid Factor IgG Antibody 2016-03-25 CDISC-2268 Update C120653 CDISC Synonym LBTEST Laboratory Test Name Remove CDISC Synonym Rheumatoid Factor Antibody IgG - - - 2016-03-25 CDISC-2268 Update C120653 CDISC Submission Value LBTEST Laboratory Test Name Update CDISC Submission Value Rheumatoid Factor Antibody IgG Rheumatoid Factor IgG Antibody 2016-03-25 CDISC-2269 Update C120654 CDISC Synonym LBTEST Laboratory Test Name Add new CDISC Synonym - - - Rheumatoid Factor IgM Antibody 2016-03-25 CDISC-2269 Update C120654 CDISC Synonym LBTEST Laboratory Test Name Remove CDISC Synonym Rheumatoid Factor Antibody IgM - - - 2016-03-25 CDISC-2269 Update C120654 CDISC Submission Value LBTEST Laboratory Test Name Update CDISC Submission Value Rheumatoid Factor Antibody IgM Rheumatoid Factor IgM Antibody 2016-03-25 CDISC-1831 Add C125939 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - ABO Blood Group 2016-03-25 CDISC-1831 Add C125940 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Amyloid A 2016-03-25 CDISC-1773 Add C125941 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Calcium, Ionized pH Adjusted 2016-03-25 CDISC-1880 Add C125942 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Calbindin 2016-03-25 CDISC-1761 Add C125943 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Carb-Deficient Transferrin/Transferrin 2016-03-25 33231 Add C125944 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Hepatitis B Virus Antibody 2016-03-25 CDISC-2158 Add C125945 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Inulin 2016-03-25 CDISC-2158 Add C125946 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Iohexol 2016-03-25 CDISC-2213 Add C125947 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Lipoarabinomannan 2016-03-25 CDISC-1831 Add C125948 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - RhD Factor 2016-03-25 CDISC-2173 Add C125949 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Urea Nitrogen Urea Nitrogen can be measured in substances other than Blood, Serum, or Plasma. This concept will replace C61019. 2016-03-25 CDISC-2173 Add C125950 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Urea Nitrogen/Creatinine Urea Nitrogen can be measured in substances other than Blood, Serum, or Plasma. This concept will replace C74753. 2016-03-25 CDISC-1853 Remove C61019 Term LBTEST Laboratory Test Name Remove term entirely from codelist Blood Urea Nitrogen - - - Urea Nitrogen can be measured in substances other than Blood, Serum, or Plasma. Therefore please use the generic code for Urea Nitrogen (C125949), which has been published with the 2016-03-25 publication. 2016-03-25 CDISC-2174 Remove C74753 Term LBTEST Laboratory Test Name Remove term entirely from codelist BUN/Creatinine - - - Urea Nitrogen can be measured in substances other than Blood, Serum, or Plasma. Therefore please use the generic code for Urea Nitrogen/Creatinine (C125950), which has been published with the 2016-03-25 publication. 2016-03-25 CDISC-1831 Add C92948 Term LBTEST Laboratory Test Name Add new term to existing codelist - - - Rh Factor 2016-03-25 CDISC-1838 Update C98706 CDISC Definition LBTEST Laboratory Test Name Update CDISC Definition A measurement of the anti-activated Factor X in a biological specimen. This test is used to monitor low molecular weight or unfractionated heparin levels in a biological specimen. A measurement of the ability of antithrombin to inactivate activated Factor X in a biological specimen. This test is used to monitor low molecular weight or unfractionated heparin levels in a biological specimen. 2016-03-25 CDISC-1606 Update C98730 CDISC Synonym LBTEST Laboratory Test Name Add new CDISC Synonym - - - Bence-Jones, Kappa 2016-03-25 CDISC-1608 Update C98732 CDISC Synonym LBTEST Laboratory Test Name Add new CDISC Synonym - - - Bence-Jones, Lambda 2016-03-25 CDISC-2175 Update C100439 CDISC Definition LBTESTCD Laboratory Test Code Update CDISC Definition A measurement of the volume of serum or plasma that would be cleared of Iohexol through excretion for a specified unit of time. A measurement of the volume of serum or plasma that would be cleared of Iohexol by excretion of urine for a specified unit of time (e.g. one minute). 2016-03-25 CDISC-2175 Update C100440 CDISC Definition LBTESTCD Laboratory Test Code Update CDISC Definition A measurement of the volume of serum or plasma that would be cleared of Ethylenediamine tetraacetic acid (EDTA) through its excretion for a specified unit of time. A measurement of the volume of serum or plasma that would be cleared of Ethylenediamine tetraacetic acid (EDTA) by excretion of urine for a specified unit of time (e.g. one minute). 2016-03-25 CDISC-2175 Update C100441 CDISC Definition LBTESTCD Laboratory Test Code Update CDISC Definition A measurement of the volume of serum or plasma that would be cleared of Diethylenetriamine pentaacetate (DTPA) through its excretion for a specified unit of time. A measurement of the volume of serum or plasma that would be cleared of Diethylenetriamine pentaacetate (DTPA) by excretion of urine for a specified unit of time (e.g. one minute). 2016-03-25 CDISC-2267 Update C120652 CDISC Synonym LBTESTCD Laboratory Test Code Add new CDISC Synonym - - - Rheumatoid Factor IgA Antibody 2016-03-25 CDISC-2267 Update C120652 CDISC Synonym LBTESTCD Laboratory Test Code Remove CDISC Synonym Rheumatoid Factor Antibody IgA - - - 2016-03-25 CDISC-2268 Update C120653 CDISC Synonym LBTESTCD Laboratory Test Code Add new CDISC Synonym - - - Rheumatoid Factor IgG Antibody 2016-03-25 CDISC-2268 Update C120653 CDISC Synonym LBTESTCD Laboratory Test Code Remove CDISC Synonym Rheumatoid Factor Antibody IgG - - - 2016-03-25 CDISC-2269 Update C120654 CDISC Synonym LBTESTCD Laboratory Test Code Add new CDISC Synonym - - - Rheumatoid Factor IgM Antibody 2016-03-25 CDISC-2269 Update C120654 CDISC Synonym LBTESTCD Laboratory Test Code Remove CDISC Synonym Rheumatoid Factor Antibody IgM - - - 2016-03-25 CDISC-1831 Add C125939 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - ABO 2016-03-25 CDISC-1831 Add C125940 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - AMYLOIDA 2016-03-25 CDISC-1773 Add C125941 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - CAIONPH 2016-03-25 CDISC-1880 Add C125942 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - CALB 2016-03-25 CDISC-1761 Add C125943 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - CDTTFRN 2016-03-25 33231 Add C125944 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - HBAB 2016-03-25 CDISC-2158 Add C125945 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - INULIN 2016-03-25 CDISC-2158 Add C125946 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - IOHEXOL 2016-03-25 CDISC-2213 Add C125947 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - LAM 2016-03-25 CDISC-1831 Add C125948 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - RHD 2016-03-25 CDISC-2173 Add C125949 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - UREAN Urea Nitrogen can be measured in substances other than Blood, Serum, or Plasma. This concept will replace C61019. 2016-03-25 CDISC-2173 Add C125950 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - UREANCRT Urea Nitrogen can be measured in substances other than Blood, Serum, or Plasma. This concept will replace C74753. 2016-03-25 CDISC-1853 Remove C61019 Term LBTESTCD Laboratory Test Code Remove term entirely from codelist BUN - - - Urea Nitrogen can be measured in substances other than Blood, Serum, or Plasma. Therefore please use the generic code for Urea Nitrogen (C125949), which has been published with the 2016-03-25 publication. 2016-03-25 CDISC-2174 Remove C74753 Term LBTESTCD Laboratory Test Code Remove term entirely from codelist BUNCREAT - - - Urea Nitrogen can be measured in substances other than Blood, Serum, or Plasma. Therefore please use the generic code for Urea Nitrogen/Creatinine (C125950), which has been published with the 2016-03-25 publication. 2016-03-25 CDISC-1831 Add C92948 Term LBTESTCD Laboratory Test Code Add new term to existing codelist - - - RH 2016-03-25 CDISC-1838 Update C98706 CDISC Definition LBTESTCD Laboratory Test Code Update CDISC Definition A measurement of the anti-activated Factor X in a biological specimen. This test is used to monitor low molecular weight or unfractionated heparin levels in a biological specimen. A measurement of the ability of antithrombin to inactivate activated Factor X in a biological specimen. This test is used to monitor low molecular weight or unfractionated heparin levels in a biological specimen. 2016-03-25 CDISC-1606 Update C98730 CDISC Synonym LBTESTCD Laboratory Test Code Add new CDISC Synonym - - - Bence-Jones, Kappa 2016-03-25 CDISC-1608 Update C98732 CDISC Synonym LBTESTCD Laboratory Test Code Add new CDISC Synonym - - - Bence-Jones, Lambda 2016-03-25 CDISC-1887 Add C12344 Term LOC Anatomical Location Add new term to existing codelist - - - CHOROID 2016-03-25 CDISC-1944 Add C12348 Term LOC Anatomical Location Add new term to existing codelist - - - MENINGES 2016-03-25 CDISC-1888 Add C12737 Term LOC Anatomical Location Add new term to existing codelist - - - IRIS 2016-03-25 CDISC-1944 Add C32446 Term LOC Anatomical Location Add new term to existing codelist - - - DELTOID MUSCLE 2016-03-25 CDISC-1849 Add C32979 Term LOC Anatomical Location Add new term to existing codelist - - - LEPTOMENINGES 2016-03-25 CDISC-1890 Add C33470 Term LOC Anatomical Location Add new term to existing codelist - - - RETINAL PIGMENTED EPITHELIAL LAYER 2016-03-25 CDISC-1944 Add C34320 Term LOC Anatomical Location Add new term to existing codelist - - - UMBILICAL CORD 2016-03-25 N/A Update C90390 NCI Preferred Term MATEST Macroscopic Findings Test Name Update NCI Preferred Term Gross Pathological Examination Gross Pathologic Examination 2016-03-25 N/A Update C90390 NCI Preferred Term MATESTCD Macroscopic Findings Test Code Update NCI Preferred Term Gross Pathological Examination Gross Pathologic Examination 2016-03-25 CDISC-2254 Update C114111 CDISC Synonym NEOPLASM Neoplasm Type Remove CDISC Synonym Diffuse Mixed Large and Small Cell Lymphoma - - - 2016-03-25 CDISC-2254 Update C114111 CDISC Submission Value NEOPLASM Neoplasm Type Update CDISC Submission Value LYMPHOMA, MIXED, MALIGNANT MIXED LYMPHOMA, MALIGNANT 2016-03-25 CDISC-2184 Add C121932 Term NEOPLASM Neoplasm Type Add new term to existing codelist - - - GIANT CELL TUMOR, BENIGN The nomenclature has been updated and now the original mapping is obsolete. This concept will replace C27477. 2016-03-25 CDISC-1796 Add C126084 Term NEOPLASM Neoplasm Type Add new term to existing codelist - - - MIXED SERTOLI-LEYDIG CELL TUMOR, BENIGN 2016-03-25 CDISC-1796 Add C126085 Term NEOPLASM Neoplasm Type Add new term to existing codelist - - - MULLERIAN TUMOR, MIXED, BENIGN 2016-03-25 CDISC-1796 Add C126086 Term NEOPLASM Neoplasm Type Add new term to existing codelist - - - NEUROENDOCRINE CELL TUMOR, BENIGN 2016-03-25 CDISC-1796 Add C126087 Term NEOPLASM Neoplasm Type Add new term to existing codelist - - - NEUROENDOCRINE CELL TUMOR, MALIGNANT This concept will replace C72074 and C3773, which have been removed with the 2016-03-25 publication. 2016-03-25 CDISC-1796 Add C126088 Term NEOPLASM Neoplasm Type Add new term to existing codelist - - - RENAL MESENCHYMAL TUMOR, MALIGNANT This concept will replace C64118, which has been removed with the 2016-03-25 publication. 2016-03-25 CDISC-2184 Remove C27477 Term NEOPLASM Neoplasm Type Remove term entirely from codelist GIANT CELL TUMOR, BENIGN - - - The nomenclature has been updated and now the original mapping is obsolete. Please use C121923 in place of C27477. 2016-03-25 CDISC-2254 Remove C2858 Term NEOPLASM Neoplasm Type Remove term entirely from codelist ADRENOCORTICAL NEOPLASM, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C2915 Term NEOPLASM Neoplasm Type Remove term entirely from codelist CARCINOID TUMOR, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C2932 Term NEOPLASM Neoplasm Type Remove term entirely from codelist CHEMODECTOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3017 Term NEOPLASM Neoplasm Type Remove term entirely from codelist EPENDYMOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3055 Term NEOPLASM Neoplasm Type Remove term entirely from codelist GIANT CELL TUMOR, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3059 Term NEOPLASM Neoplasm Type Remove term entirely from codelist NEUROGLIAL TUMOR, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3070 Term NEOPLASM Neoplasm Type Remove term entirely from codelist GRANULOSA CELL TUMOR, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3087 Term NEOPLASM Neoplasm Type Remove term entirely from codelist HEMANGIOPERICYTOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3146 Term NEOPLASM Neoplasm Type Remove term entirely from codelist KERATOACANTHOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3188 Term NEOPLASM Neoplasm Type Remove term entirely from codelist LEYDIG CELL TUMOR, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3230 Term NEOPLASM Neoplasm Type Remove term entirely from codelist MENINGIOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3234 Term NEOPLASM Neoplasm Type Remove term entirely from codelist MESOTHELIOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3262 Term NEOPLASM Neoplasm Type Remove term entirely from codelist NEOPLASM, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3286 Term NEOPLASM Neoplasm Type Remove term entirely from codelist ODONTOGENIC TUMOR, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3288 Term NEOPLASM Neoplasm Type Remove term entirely from codelist OLIGODENDROGLIOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3308 Term NEOPLASM Neoplasm Type Remove term entirely from codelist PARAGANGLIOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3326 Term NEOPLASM Neoplasm Type Remove term entirely from codelist PHEOCHROMOCYTOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3340 Term NEOPLASM Neoplasm Type Remove term entirely from codelist POLYP, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3403 Term NEOPLASM Neoplasm Type Remove term entirely from codelist TERATOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3411 Term NEOPLASM Neoplasm Type Remove term entirely from codelist THYMOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3486 Term NEOPLASM Neoplasm Type Remove term entirely from codelist LEIOMYOBLASTOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C35765 Term NEOPLASM Neoplasm Type Remove term entirely from codelist HISTIOCYTOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3738 Term NEOPLASM Neoplasm Type Remove term entirely from codelist OSTEOCLASTOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3764 Term NEOPLASM Neoplasm Type Remove term entirely from codelist POLYP, ADENOMATOUS, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3773 Term NEOPLASM Neoplasm Type Remove term entirely from codelist CARCINOMA, NEUROENDOCRINE CELL, MALIGNANT - - - Replace with NEUROENDOCRINE CELL TUMOR, MALIGNANT (C126087). Please use C126087 in place of 3773. 2016-03-25 CDISC-2254 Remove C3788 Term NEOPLASM Neoplasm Type Remove term entirely from codelist GANGLIOGLIOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C3794 Term NEOPLASM Neoplasm Type Remove term entirely from codelist STROMAL TUMOR, GONADAL, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Update C3798 CDISC Synonym NEOPLASM Neoplasm Type Remove CDISC Synonym MPNST - - - 2016-03-25 CDISC-2254 Update C3798 CDISC Synonym NEOPLASM Neoplasm Type Remove CDISC Synonym Malignant Neoplasm of Peripheral Nerve Sheath - - - 2016-03-25 CDISC-2254 Update C3798 CDISC Synonym NEOPLASM Neoplasm Type Remove CDISC Synonym Malignant Neoplasm of the Peripheral Nerve Sheath - - - 2016-03-25 CDISC-2254 Update C3798 CDISC Synonym NEOPLASM Neoplasm Type Remove CDISC Synonym Malignant Neurilemoma - - - 2016-03-25 CDISC-2254 Update C3798 CDISC Synonym NEOPLASM Neoplasm Type Remove CDISC Synonym Malignant Peripheral Nerve Sheath Neoplasm - - - 2016-03-25 CDISC-2254 Update C3798 CDISC Synonym NEOPLASM Neoplasm Type Remove CDISC Synonym Malignant Schwannoma - - - 2016-03-25 CDISC-2254 Update C3798 CDISC Synonym NEOPLASM Neoplasm Type Remove CDISC Synonym Malignant Tumor of Peripheral Nerve Sheath - - - 2016-03-25 CDISC-2254 Update C3798 CDISC Synonym NEOPLASM Neoplasm Type Remove CDISC Synonym Malignant Tumor of the Peripheral Nerve Sheath - - - 2016-03-25 CDISC-2254 Update C3798 CDISC Submission Value NEOPLASM Neoplasm Type Update CDISC Submission Value PERIPHERAL NERVE SHEATH TUMOR, MALIGNANT SCHWANNOMA, MALIGNANT 2016-03-25 CDISC-2254 Update C3903 CDISC Submission Value NEOPLASM Neoplasm Type Update CDISC Submission Value GLIOMA, MIXED, MALIGNANT MIXED GLIOMA, MALIGNANT 2016-03-25 CDISC-1796 Remove C4209 Term NEOPLASM Neoplasm Type Remove term entirely from codelist ARRHENOBLASTOMA, BENIGN - - - 2016-03-25 CDISC-1796 Remove C4210 Term NEOPLASM Neoplasm Type Remove term entirely from codelist ARRHENOBLASTOMA, MALIGNANT - - - 2016-03-25 CDISC-2254 Remove C4313 Term NEOPLASM Neoplasm Type Remove term entirely from codelist AMELOBLASTOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C48306 Term NEOPLASM Neoplasm Type Remove term entirely from codelist PHEOCHROMOCYTOMA, COMPLEX, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C4858 Term NEOPLASM Neoplasm Type Remove term entirely from codelist DECIDUOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-1938 Add C5367 Term NEOPLASM Neoplasm Type Add new term to existing codelist - - - CARDIAC SCHWANNOMA, MALIGNANT 2016-03-25 CDISC-2254 Remove C60781 Term NEOPLASM Neoplasm Type Remove term entirely from codelist ASTROCYTOMA, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-1796 Remove C64118 Term NEOPLASM Neoplasm Type Remove term entirely from codelist MESENCHYMAL TUMOR, MALIGNANT - - - Replace with RENAL MESENCHYMAL TUMOR, MALIGNANT (C126088). Please use C126088 in place of C64118. 2016-03-25 CDISC-2254 Remove C6930 Term NEOPLASM Neoplasm Type Remove term entirely from codelist MIXED TUMOR, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C6963 Term NEOPLASM Neoplasm Type Remove term entirely from codelist NEURAL CREST TUMOR, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C72074 Term NEOPLASM Neoplasm Type Remove term entirely from codelist CARCINOID TUMOR, MALIGNANT - - - Replace with NEUROENDOCRINE CELL TUMOR, MALIGNANT (C126087). Please use C126087 in place of C72074. 2016-03-25 CDISC-2254 Remove C7367 Term NEOPLASM Neoplasm Type Remove term entirely from codelist HAIR FOLLICLE NEOPLASM, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C82973 Term NEOPLASM Neoplasm Type Remove term entirely from codelist ADRENAL TUMOR, SUBCAPSULAR, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C8402 Term NEOPLASM Neoplasm Type Remove term entirely from codelist HISTIOCYTOMA, FIBROUS, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Update C8975 CDISC Synonym NEOPLASM Neoplasm Type Add new CDISC Synonym - - - MMMT 2016-03-25 CDISC-2254 Update C8975 CDISC Synonym NEOPLASM Neoplasm Type Remove CDISC Synonym Malignant Mixed Mullerian Tumor - - - 2016-03-25 CDISC-2254 Update C8975 CDISC Synonym NEOPLASM Neoplasm Type Remove CDISC Synonym Mmmt - - - 2016-03-25 CDISC-2254 Update C8975 CDISC Definition NEOPLASM Neoplasm Type Update CDISC Definition A malignant neoplasm of the female reproductive system (mostly uterus and ovaries) originating from the Muellerian ducts and composed of carcinomatous and sarcomatous elements. A malignant neoplasm of the female reproductive tract (mostly uterus and ovaries) originating from the Mullerian ducts and composed of carcinomatous and sarcomatous elements. 2016-03-25 CDISC-2254 Update C8975 CDISC Submission Value NEOPLASM Neoplasm Type Update CDISC Submission Value MUELLERIAN TUMOR, MIXED, MALIGNANT MIXED MULLERIAN TUMOR, MALIGNANT 2016-03-25 CDISC-2254 Remove C9295 Term NEOPLASM Neoplasm Type Remove term entirely from codelist MAST CELL TUMOR, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-2254 Remove C98794 Term NEOPLASM Neoplasm Type Remove term entirely from codelist SERTOLI CELL TUMOR, UNDETERMINED - - - The FDA requires non-clinical sponsors to identify Benign or Malignant so this concept would never be used. 2016-03-25 CDISC-1275 Add C126089 Term NONNEO Non-Neoplastic Finding Type Add new term to existing codelist - - - NEEDLE TRACT LESION 2016-03-25 CDISC-2194 Update C2978 CDISC Synonym NONNEO Non-Neoplastic Finding Type Remove CDISC Synonym Cysts - - - 2016-03-25 CDISC-1793 Update C35541 CDISC Synonym NONNEO Non-Neoplastic Finding Type Add new CDISC Synonym - - - Increased Keratinization 2016-03-25 CDISC-2068 Add C120721 Term OMTEST Organ Measurement Test Name Add new term to existing codelist - - - Thickness, Mean 2016-03-25 CDISC-2060 Add C41145 Term OMTEST Organ Measurement Test Name Add new term to existing codelist - - - Thickness 2016-03-25 CDISC-2068 Add C120721 Term OMTESTCD Organ Measurement Test Code Add new term to existing codelist - - - THCKNMN 2016-03-25 CDISC-2060 Add C41145 Term OMTESTCD Organ Measurement Test Code Add new term to existing codelist - - - THCKN 2016-03-25 CDISC-2261 Remove C67331 Term PKUNIT PK Units of Measure Remove term entirely from codelist pg/dL - - - 2016-03-25 CDISC-2261 Remove C67430 Term PKUNIT PK Units of Measure Remove term entirely from codelist ng/mL/h - - - 2016-03-25 CDISC-2261 Remove C69188 Term PKUNIT PK Units of Measure Remove term entirely from codelist nL - - - 2016-03-25 CDISC-2261 Update C85601 CDISC Synonym PKUNIT PK Units of Measure Remove CDISC Synonym g/h - - - 2016-03-25 CDISC-2261 Update C85601 CDISC Synonym PKUNIT PK Units of Measure Remove CDISC Synonym gram/h - - - 2016-03-25 CDISC-2261 Update C85601 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition Grams per hour. A unit of mass flow rate or dose administration rate equal to one gram per hour. 2016-03-25 CDISC-2261 Update C85602 CDISC Synonym PKUNIT PK Units of Measure Remove CDISC Synonym g/min - - - 2016-03-25 CDISC-2261 Update C85602 CDISC Synonym PKUNIT PK Units of Measure Remove CDISC Synonym gram/min - - - 2016-03-25 CDISC-2261 Update C85602 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition Grams per minute. A unit of mass flow rate or dose administration rate equal to one gram per minute. 2016-03-25 CDISC-2261 Remove C85631 Term PKUNIT PK Units of Measure Remove term entirely from codelist h*nmol/L/umol - - - 2016-03-25 CDISC-2261 Update C85646 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition International units per hour. A unit of substance (biologic activity) flow rate equal to one international unit per hour. 2016-03-25 CDISC-2261 Update C85647 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition International units per minute. A unit of substance (biologic activity) flow rate equal to one international unit per minute. 2016-03-25 CDISC-2261 Remove C85703 Term PKUNIT PK Units of Measure Remove term entirely from codelist ug/inh - - - 2016-03-25 CDISC-2261 Remove C85704 Term PKUNIT PK Units of Measure Remove term entirely from codelist ug/puff - - - 2016-03-25 CDISC-2261 Update C85707 CDISC Synonym PKUNIT PK Units of Measure Remove CDISC Synonym mcmol/h - - - 2016-03-25 CDISC-2261 Update C85707 CDISC Synonym PKUNIT PK Units of Measure Remove CDISC Synonym umol/h - - - 2016-03-25 CDISC-2261 Update C85707 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition Micromoles per hour. A unit of substance flow rate equal to one micromole per hour. 2016-03-25 CDISC-2261 Remove C85711 Term PKUNIT PK Units of Measure Remove term entirely from codelist mg/mL/h - - - 2016-03-25 CDISC-2261 Update C85720 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition Millimoles per hour. A unit of substance flow rate equal to one millimole per hour. 2016-03-25 CDISC-2261 Remove C85721 Term PKUNIT PK Units of Measure Remove term entirely from codelist mmol/mL/h - - - 2016-03-25 CDISC-2261 Update C85722 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition Millimoles per minute. A unit of substance flow rate equal to one millimole per minute. 2016-03-25 CDISC-2261 Update C85738 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition Moles per hour. A unit of substance flow rate equal to one mole per hour. 2016-03-25 CDISC-2261 Update C85739 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition Moles per minute. A unit of substance flow rate equal to one mole per minute. 2016-03-25 CDISC-2261 Update C85741 CDISC Synonym PKUNIT PK Units of Measure Remove CDISC Synonym ng/d - - - 2016-03-25 CDISC-2261 Update C85741 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition Nanograms per day. A unit of mass flow rate equal to one nanogram per day. 2016-03-25 CDISC-2261 Update C85742 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition Nanograms per hour. A unit of mass flow rate equal to one nanogram per hour. 2016-03-25 CDISC-2261 Update C85749 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition Nanograms per minute. A unit of mass flow rate equal to one nanogram per minute. 2016-03-25 CDISC-2261 Update C85753 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition Nanomoles per hour. A unit of substance flow rate equal to one nanomole per hour. 2016-03-25 CDISC-2261 Remove C85757 Term PKUNIT PK Units of Measure Remove term entirely from codelist nmol/mL/h - - - 2016-03-25 CDISC-2261 Update C85758 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition Nanomoles per minute. A unit of substance flow rate equal to one nanomole per minute. 2016-03-25 CDISC-2261 Remove C85760 Term PKUNIT PK Units of Measure Remove term entirely from codelist nU/mL - - - 2016-03-25 CDISC-2261 Update C85778 CDISC Synonym PKUNIT PK Units of Measure Remove CDISC Synonym pg/d - - - 2016-03-25 CDISC-2261 Update C85778 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition Picograms per day. A unit of mass flow rate equal to one picogram per day. 2016-03-25 CDISC-2261 Update C85779 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition Picograms per hour. A unit of mass flow rate equal to one picogram per hour. 2016-03-25 CDISC-2261 Remove C85780 Term PKUNIT PK Units of Measure Remove term entirely from codelist pg/mg Creatinine - - - Creatinine belongs in test/parm name. Please use pg/mg (C67396) in its place. 2016-03-25 CDISC-2261 Update C85782 CDISC Definition PKUNIT PK Units of Measure Update CDISC Definition Picograms per minute. A unit of mass flow rate equal to one picogram per minute. 2016-03-25 CDISC-1831 Add C81009 Term PORTOT Portion/Totality Add new term to existing codelist - - - HEMI 2016-03-25 CDISC-1348; CDISC-1940 Update C112234 CDISC Definition SPEC Specimen Update CDISC Definition A superficial muscle located in the midline of the perineum and anterior to the anus. It covers the bulb of the penis in males and the vestibular bulb in females. The origin and insertion differs between males and females. (NCI) A superficial muscle located on the midline of the perineum. It covers the bulb of the penis in males and the vestibular bulb in females. 2016-03-25 CDISC-1348; CDISC-1940 Update C112234 CDISC Submission Value SPEC Specimen Update CDISC Submission Value BULBOSPONGIOSUS MUSCLE, BULBOSPONGIOSUS 2016-03-25 CDISC-1670; CDISC-1699 Remove C12313 Term SPEC Specimen Remove term entirely from codelist GLAND, ENDOMETRIAL - - - 2016-03-25 CDISC-2179 Add C125895 Term SPEC Specimen Add new term to existing codelist - - - GLAND, ANAL SAC This term replaces C77621, which has been removed from the codelist with the 2016-03-25 publication. 2016-03-25 CDISC-1741 Add C125896 Term SPEC Specimen Add new term to existing codelist - - - SAC, ANAL 2016-03-25 CDISC-2180 Add C125897 Term SPEC Specimen Add new term to existing codelist - - - FLUID, THORAX Incorrect CDISC submission value initially assigned to C77613. If Thoracic Fluid is required please use this concept. 2016-03-25 CDISC-1940 Add C12778 Term SPEC Specimen Add new term to existing codelist - - - ARTERY, RENAL 2016-03-25 CDISC-1741 Remove C32068 Term SPEC Specimen Remove term entirely from codelist SAC, ANAL - - - 2016-03-25 CDISC-1940 Add C32814 Term SPEC Specimen Add new term to existing codelist - - - ARTERY, BRACHIOCEPHALIC 2016-03-25 CDISC-1348 Remove C33581 Term SPEC Specimen Remove term entirely from codelist ARTERY, SPERMATIC - - - 2016-03-25 CDISC-1670; CDISC-1699 Add C33842 Term SPEC Specimen Add new term to existing codelist - - - GLAND, ENDOMETRIAL 2016-03-25 CDISC-1940 Add C52902 Term SPEC Specimen Add new term to existing codelist - - - MUSCLE, ERECTOR SPINAE 2016-03-25 CDISC-1670; CDISC-1699 Remove C74586 Term SPEC Specimen Remove term entirely from codelist GLAND, ACCESSORY OCULAR - - - 2016-03-25 CDISC-1348 Remove C77609 Term SPEC Specimen Remove term entirely from codelist BONE MARROW SMEAR - - - Incorrect granularity in the term. Please use BONE MARROW (C12431) as the specimen. Smear is the specimen preparation method. 2016-03-25 CDISC-1543 Update C77613 CDISC Synonym SPEC Specimen Remove CDISC Synonym Pleural Fluid - - - 2016-03-25 CDISC-1543 Update C77613 CDISC Submission Value SPEC Specimen Update CDISC Submission Value FLUID, THORACIC FLUID, PLEURAL Incorrect CDISC submission value initially assigned to this term. This concept should be used for Pleural Fluid only. If Thoracic Fluid is required, please use FLUID, THORAX (C125897), published with 2016-03-25 publication. 2016-03-25 CDISC-1670; CDISC-1699 Remove C77615 Term SPEC Specimen Remove term entirely from codelist GIZZARD - - - In avian species, the gizzard is synonymous with ventriculus. Please map this concept to the existing published term VENTRICULUS (C114236). 2016-03-25 CDISC-1670; CDISC-1699 Remove C77621 Term SPEC Specimen Remove term entirely from codelist GLAND, PERINEAL - - - Perineal Gland not used by pre-clinical. Please map this concept to the new term GLAND, ANAL SAC (C125895), which is published with the 2016-03-25 publication. 2016-03-25 CDISC-1543 Remove C77671 Term SPEC Specimen Remove term entirely from codelist FOOT/FOOTPAD - - - 2016-03-25 CDISC-2160 Remove C14252 Term SPECIES Species Remove term entirely from codelist BABOON - - - This term was determined to be a STRAIN by the SEND CT team. The SPECIES should be mapped to MONKEY. 2016-03-25 CDISC-2160 Remove C77115 Term SPECIES Species Remove term entirely from codelist MARMOSET - - - This term was determined to be a STRAIN by the SEND CT team. The SPECIES should be mapped to MONKEY. 2016-03-25 CDISC-2254 Update C79388 CDISC Definition SSTYP SEND Study Type Update CDISC Definition A toxicology study that assesses the and effects of a substance on juveniles before reaching puberty. A toxicology study that assesses the effects of a substance on a subject that received treatment and/or was dosed beginning during the juvenile stage of development. 2016-03-25 CDISC-2160 Add C14252 Term STRAIN Strain/Substrain Add new term to existing codelist - - - BABOON Moved from SPECIES to STRAIN codelist. The SPECIES should be mapped to MONKEY. 2016-03-25 CDISC-2160 Add C77115 Term STRAIN Strain/Substrain Add new term to existing codelist - - - MARMOSET Moved from SPECIES to STRAIN codelist. The SPECIES should be mapped to MONKEY. 2016-03-25 CDISC-2254 Remove C90372 Term STSPRM SEND Trial Summary Parameter Test Name Remove term entirely from codelist Class of Compound - - - SEND CT team determined a more specific level of granularity was needed for this concept. Therefore please map this to the new term Pharmacologic Class (C98768), which has been published with the 2016-03-25 publication. 2016-03-25 CDISC-2254 Add C98768 Term STSPRM SEND Trial Summary Parameter Test Name Add new term to existing codelist - - - Pharmacologic Class This term replaces C90372, which was determined to be more generic than required. 2016-03-25 CDISC-2254 Remove C90372 Term STSPRMCD SEND Trial Summary Parameter Test Code Remove term entirely from codelist CLASS - - - SEND CT team determined a more specific level of granularity was needed for this concept. Therefore please map this to the new term Pharmacologic Class (C98768), which has been published with the 2016-03-25 publication. 2016-03-25 CDISC-2254 Add C98768 Term STSPRMCD SEND Trial Summary Parameter Test Code Add new term to existing codelist - - - PCLASS This term replaces C90372, which was determined to be more generic than required. 2016-03-25 CDISC-1810 Add C126078 Term UNIT Unit Add new term to existing codelist - - - Absorbance U/mL 2016-03-25 CDISC-1760 Add C126079 Term UNIT Unit Add new term to existing codelist - - - copies/ug 2016-03-25 CDISC-1832 Add C126080 Term UNIT Unit Add new term to existing codelist - - - mm3/mm2/year 2016-03-25 CDISC-1832 Add C126081 Term UNIT Unit Add new term to existing codelist - - - um/day 2016-03-25 CDISC-1831 Add C126082 Term UNIT Unit Add new term to existing codelist - - - umol/kg/min 2016-03-25 CDISC-2225 Update C73686 CDISC Definition UNIT Unit Update CDISC Definition A unit of optical density expressed as the absorbance of light transmitted through the medium on the logarithmic scale. (NCI) A unit of optical density expressed as a logarithm of absorbance of light transmitted through a partially absorbing substance. 2016-03-25 CDISC-2225 Update C73686 CDISC Submission Value UNIT Unit Update CDISC Submission Value AU Absorbance U 2016-03-25 CDISC-2225 Update C73687 CDISC Submission Value UNIT Unit Update CDISC Submission Value AU/min Absorbance U/min 2016-03-25 CDISC-1691 Update C73721 CDISC Synonym UNIT Unit Add new CDISC Synonym - - - mg/mmol 2016-03-25 CDISC-1691 Update C73721 CDISC Synonym UNIT Unit Remove CDISC Synonym Gram per Mole - - - 2016-03-25 CDISC-1833 Add C73772 Term UNIT Unit Add new term to existing codelist - - - Gravitational Unit 2016-03-25 CDISC-1807 Add C126083 Term VSTEST Vital Signs Test Name Add new term to existing codelist - - - Basal Metabolic Rate 2016-03-25 CDISC-1807 Add C126083 Term VSTESTCD Vital Signs Test Code Add new term to existing codelist - - - BMR