Release Date	Request Code	NCIt Code	CDISC Term Type	Change Summary	Original	New
2009-07-06	18857	C74614	Definition	Modify definition for May-Hegglin Anomaly in SDTM-LBTEST and SDTM-LBTESTCD codelists.	Def: A measurement of the amount of May-Hegglin anomaly present in a blood sample.	Def: A measurement of the May-Hegglin anomaly in a blood sample. This anomaly is characterized by large, misshapen platelets and the presence of Dohle bodies in leukocytes.
2009-07-06	18881	C64433	Synonym	Add SY for ALT: SGPT in SDTM-LBTEST, SDTM-LBTESTCD codelists.	- - -	SY: SGPT
2009-07-06	19122	C64467	Synonym	Add SY for AST: SGOT in SDTM-LBTEST, SDTM-LBTESTCD codelists.	- - -	SY: SGOT
2009-07-06	19125	C61032	Synonym	Add SY for Cholesterol: Total Cholesterol in SDTM-LBTEST, SDTM-LBTESTCD codelists.	- - -	SY: Total Cholesterol
2009-07-06	19449	C64549	Synonym	Add SY for Elliptocytes: Ovalocytes in SDTM-LBTEST, SDTM-LBTESTCD codelists.	- - -	SY: Ovalocytes
2009-07-06	19452	C74782	Synonym	Add SY for Estradiol: Oestradiol in SDTM-LBTEST, SDTM-LBTESTCD codelists.	- - -	SY: Oestradiol
2009-07-06	19454	C74676	Preferred Term	Change SDTM-LBTESTCD PT from FOLICAC to VITB9.	PT: FOLICAC	PT: VITB9
2009-07-06	19455	C64847	Definition	Modify definition of Gamma Glutamyl Transferase in LBTEST and LBTESTCD codelists. Change Transpeptidase to Transferase.	Def: A measurement of the gamma glutamyl transpeptidase in a biological specimen.	Def: A measurement of the gamma glutamyl transferase in a biological specimen.
2009-07-06	19456	C64851	Synonym	Add SY for HCG: Pregnancy Test in SDTM-LBTEST, SDTM-LBTESTCD codelists.	- - -	SY: Pregnancy Test
2009-07-06	19457	C74739	Synonym	Add SY to term Glutamate: Glutamic Acid in SDTM-LBTEST, SDTM-LBTESTCD codelists.	- - -	SY: Glutamic Acid
2009-07-06	19542	C16334	Definition	Add definition for Bermuda in SDTM-COUNTRY codelist.	- - -	Def: A group of islands in the North Atlantic Ocean, east of South Carolina.
2009-07-06	19574	C64798	Preferred Term, Synonym	Change SDTM-LBTEST PT from Ery. Mean Corpuscular HB Concentration to Ery. Mean Corpuscular HGB Concentration. 	PT: Ery. Mean Corpuscular HB Concentration	PT/SY: Ery. Mean Corpuscular HGB Concentration
2009-07-06	19585	C64857	Synonym	Add SY to term Phosphate: Phosphorus in SDTM-LBTEST, SDTM-LBTESTCD codelists.	- - -	SY: Phosphorus
2009-07-06	19653	C48227	Definition	Modify definition of 'LOST TO FOLLOW-UP' in SDTM-NCOMPLT codelist.	Def: The loss or lack of continuation of follow-up after a study has officially closed. See Follow-up. (NCI)	Def: The loss or lack of continuation of a subject to follow-up.
2009-07-06	19678	C41340	Definition	Modify definition of 'SEVERE' in SDTM-AESEV, SDTM-TOXGR codelist.	Def: A type of adverse event that requires intensive therapeutic intervention. The event interrupts usual activities of daily living, or significantly affects clinical status. The event possesses a significant risk of harm to the research participant and hospitalization may be required.	Def: A type of adverse event that interrupts usual activities of daily living, or significantly affects clinical status, or may require intensive therapeutic intervention.
2009-07-06	19682	C51946	Synonym	Add SY for Erythrocytes: Red Blood Cells in SDTM-LBTEST, SDTM-LBTESTCD codelists.	- - -	SY: Red Blood Cells
2009-07-06	19683	C74705	Synonym	Add SY for term RBCNUC: Nucleated Red Blood Cells in SDTM-LBTEST, SDTM-LBTESTCD codelists.	- - -	SY: Nucleated Red Blood Cells
2009-07-06	19684	C74647	Synonym	Add SY for Nucleated Erythrocytes/Erythrocytes: Nucleated Red Blood Cells/Erythrocytes in SDTM-LBTEST, SDTM-LBTESTCD codelists.	- - -	SY: Nucleated Red Blood Cells/Erythrocytes
2009-07-06	19688	C64801	Synonym	Add SY for Dacryocytes: Tear Shaped Erythrocytes in SDTM-LBTEST, SDTM-LBTESTCD codelists.	- - -	SY: Tear Shaped Erythrocytes
2009-07-06	19689	C64814	Synonym	Add SY for Urate: Uric Acid in SDTM-LBTEST, SDTM-LBTESTCD codelists.	- - -	SY: Uric Acid
2009-07-06	19690	C51948	Synonym	Add SY for WBC: White Blood Cells in SDTM-LBTEST, SDTM-LBTESTCD codelists.	- - -	SY: White Blood Cells
2009-07-06	19704	C66727	Definition	Modify definition of 'NCOMPLT' in SDTM-NCOMPLT codelist.	Def: The reason that a subject was discontinued from a clinical trial.	Def: The status of the subject's completion of the study or a segment of the study, or the reason the subject discontinued the study or segment of the study.
2009-07-06	19750	C74792, C75386	Preferred Term, Synonym	Change PT and code of 'Somatotropin' to 'Somatotrophin' from codelist SDTM-LBTEST and SDTM-LBTESTCD. Additionally, Somatotrophin and C75386 Growth Hormone are synonyms. Remove C75386 from LBTEST and LBTESTCD codelists and add Growth Hormone as a synonym of C80360.	Code: C74792; PT: Somatotropin; PT: Growth Hormone	Code: C80360; PT: Somatotrophin; SY: Growth Hormone; Def: A measurement of the somatotrophin (growth) hormone in a biological specimen. Removed C75386 Growth Hormone/GRWH from LBTEST and LBTESTCD codelist.
2009-07-06	19904	C74676	Preferred Term	Change SDTM-LBTEST PT from Folic Acid to Vitamin B9.	PT: Folic Acid	PT: Vitamin B9, SY: Folic Acid
2009-07-06	20796	C74768	Definition	Misspelling in definition for 'Granular Casts' in SDTM-LBTEST, SDTM-LBTESTCD codelist.	Def: A measurement of the granular (course and fine) casts present in a urine specimen.	Def: A measurement of the granular (coarse and fine) casts present in a urine specimen.
2009-07-06	20964	C49641	Definition	Misspelling in Definition for 'In Utero' in SDTM-AGESPAN codelist.	Def: The period of time during which the embryo or foetus is present in the uterus of the female. Also describes the location of the embryo or foetus as being in the uterus in contrast to outside the uterus (ex utero). (NCI)	Def: The period of time during which the embryo or fetus is present in the uterus of the female. Also describes the location of the embryo or fetus as being in the uterus in contrast to outside the uterus (ex utero). (NCI)
2009-07-06	20967	C34786	Definition	Misspelling in Definition for 'VENTRICULAR ARRHYTHMIA ASSOCIATED WITH LONG QT SYNDROME' in SDTM-EGSTRESC codelist.	A ventricular arrhythmia characterized by syncopal episodes and a long QT interval, sometimes leading to sudden death due to paroxysmal ventricular arrhythmia. This arrhythmia is associated with a prolongation of repolarisation following depolarization of the cardiac ventricles. The prolongation of the Q-T interval combined with torsades de pointes manifests as several different forms; some may be acquired or congenital; some may lead to serious arrhythmia and sudden cardiac death. (NCI)	A ventricular arrhythmia characterized by syncopal episodes and a long QT interval, sometimes leading to sudden death due to paroxysmal ventricular arrhythmia. This arrhythmia is associated with a prolongation of repolarization following depolarization of the cardiac ventricles. The prolongation of the Q-T interval combined with torsades de pointes manifests as several different forms; some may be acquired or congenital; some may lead to serious arrhythmia and sudden cardiac death. (NCI)
2009-07-06	20969	C42554	Definition	Misspelling in Definition for Ohm in SDTM-VSRESU codelist.	Def: A unit of electrical resistance equal to the resistance between two points on a conductor when a potential difference of one volt between them produces a current of one Ampere. Ohm is also used to measure impedance and reactance for complex resistance. A measurement in ohms is the reciprocal of a measurement in siemens.(NCI)	Def: A unit of electrical resistance equal to the resistance between two points on a conductor when a potential difference of one volt between them produces a current of one Ampere. Ohm is also used to measure impedance and reactance for complex resistance. A measurement in ohms is the reciprocal of a measurement in Siemens.(NCI)
2009-07-06	20970	C42555	Definition	Misspelling in Definition for Siemens in SDTM-UNIT codelist.	A unit of electrical conductance, admittance, and susceptance. A conductor has a conductance of one siemens if an electrical potential difference of one volt produces a one Ampere current in it. The conductance in siemens is the reciprocal of its resistance in ohms.(NCI)	A unit of electrical conductance, admittance, and susceptance. A conductor has a conductance of one Siemens if an electrical potential difference of one volt produces a one Ampere current in it. The conductance in Siemens is the reciprocal of its resistance in ohms.(NCI)
2009-07-06	20971	C42554	Definition	Misspelling in Definition for Ohm in SDTM-UNIT codelist.	Def: A unit of electrical resistance equal to the resistance between two points on a conductor when a potential difference of one volt between them produces a current of one ampere. Ohm is also used to measure impedance and reactance for complex resistance. A measurement in ohms is the reciprocal of a measurement in siemens.(NCI)	Def: A unit of electrical resistance equal to the resistance between two points on a conductor when a potential difference of one volt between them produces a current of one Ampere. Ohm is also used to measure impedance and reactance for complex resistance. A measurement in ohms is the reciprocal of a measurement in Siemens.(NCI)
2009-07-06	20972	C42558	Definition	Misspelling in Definition for Henry in SDTM-UNIT codelist.	Def: A unit of electric inductance. A coil with an inductance of one Henry requires a flux of one weber for each Ampere of induced current. If it is the current which changes, then the induced field will generate a potential difference within the coil: if the inductance is one henry a current change of one Ampere per second generates a potential difference of one volt. The Henry is a large unit; inductances in practical circuits are measured in millihenrys or microhenrys.(NCI)	Def: A unit of electric inductance. A coil with an inductance of one Henry requires a flux of one Weber for each Ampere of induced current. If it is the current which changes, then the induced field will generate a potential difference within the coil: if the inductance is one Henry a current change of one Ampere per second generates a potential difference of one volt. The Henry is a large unit; inductances in practical circuits are measured in milliHenrys or microHenrys.(NCI)
2009-07-06	20973	C44277	Definition	Misspelling in Definition for F in SDTM-VSRESU codelist.	Def: The Fahrenheit temperature scale is named after the German physicist Gabriel Fahrenheit (1686-1736), who proposed it in 1724. In this scale, the freezing point of water is 32 degrees Fahrenheit and the boiling point is 212 degrees, placing the boiling and melting points of water 180 degrees apart. In this scale a degree Fahrenheit is 5/9ths of a kelvin (or of a degree Celsius), and minus 40 degrees Fahrenheit is equal to minus 40 degrees Celsius. (NCI)	Def: The Fahrenheit temperature scale is named after the German physicist Gabriel Fahrenheit (1686-1736), who proposed it in 1724. In this scale, the freezing point of water is 32 degrees Fahrenheit and the boiling point is 212 degrees, placing the boiling and melting points of water 180 degrees apart. In this scale a degree Fahrenheit is 5/9ths of a Kelvin (or of a degree Celsius), and minus 40 degrees Fahrenheit is equal to minus 40 degrees Celsius. (NCI)
2009-07-06	20975	C54711	Definition	Misspelling in Definition for 'atm' in SDTM-UNIT codelist.	Def: A unit of pressure, equal to a barometer reading of 760 mm Hg. 1 atmosphere is 101325 pascals and 1.01325 bar. This unit of pressure is roughly equal to the average atmospheric pressure at sea level on the earth.(NCI)	Def: A unit of pressure, equal to a barometer reading of 760 mm Hg. 1 atmosphere is 101325 Pascals and 1.01325 bar. This unit of pressure is roughly equal to the average atmospheric pressure at sea level on the earth.(NCI)
2009-07-06	20977	C68915	Definition	Misspelling in Definition for 'Gauss' in SDTM-UNIT codelist.	Def: The unit of magnetic flux density. A field of one Gauss exerts a force on a conductor, placed in the field of 0.1 dyne per Ampere of current per centimeter of conductor. One Gauss represents a magnetic flux of one Maxwell per square centimeter of cross-section perpendicular to the field. One Gauss equals 10-4 tesla.(NCI)	Def: The unit of magnetic flux density. A field of one Gauss exerts a force on a conductor, placed in the field of 0.1 dyne per Ampere of current per centimeter of conductor. One Gauss represents a magnetic flux of one Maxwell per square centimeter of cross-section perpendicular to the field. One Gauss equals 10-4 Tesla.(NCI)
2009-07-06	20978	C70511	Definition	Misspelling in Definition for 'kBQ' in SDTM-UNIT codelist.	Def: A unit of radioactivity equal to one thousand nuclear disintegrations or other nuclear transformations per second, or to 10E3 becquerels.(NCI)	Def: A unit of radioactivity equal to one thousand nuclear disintegrations or other nuclear transformations per second, or to 10E3 Becquerels.(NCI)
2009-07-06	20978	C70512	Definition	Misspelling in Definition for 'MBQ' in SDTM-UNIT codelist.	Def: A unit of radioactivity equal to one million nuclear disintegrations or other nuclear transformations per second, or to 10E6 becquerels.(NCI)	Def: A unit of radioactivity equal to one million nuclear disintegrations or other nuclear transformations per second, or to 10E6 Becquerels.(NCI)
2009-07-06	20978	C70513	Definition	Misspelling in Definition for 'GBQ' in SDTM-UNIT codelist.	Def: A unit of radioactivity equal to one billion nuclear disintegrations or other nuclear transformations per second, or to 10E9 becquerels.(NCI)	Def: A unit of radioactivity equal to one billion nuclear disintegrations or other nuclear transformations per second, or to 10E9 Becquerels.(NCI)
2009-07-06	20978	C71168	Definition	Misspelling in Definition for 'kBq/uL' in SDTM-UNIT codelist.	Def: A unit of volumetric radioactivity concentration defined as a concentration of a radionuclide with an activity equal to one thousand becquerels per unit volume equal to one millionth of a liter.(NCI)	Def: A unit of volumetric radioactivity concentration defined as a concentration of a radionuclide with an activity equal to one thousand Becquerels per unit volume equal to one millionth of a liter.(NCI)
2009-07-06	20980	C71061	Definition	Misspelling in Definition for 'FASCICULAR TACHYCARDIA' in SDTM-EGSTRESC codelist.	Def: A distinct subgroup of idiopathic ventricular tachycardia (VT) that may be confused with either typical VT or supraventricular tachycardia (SVT). It is characterised by the absence of structural heart disease and classic electrocardiographic and electrophysiological features. It originates from the region of the posterior fascicle (or occasionally the anterior fascicle) of the left bundle branch and is partly propagated by the His-Purkinje network. It therefore produces QRS complexes of relatively short duration (0.11-0.14)s. (NCI)	Def: A distinct subgroup of idiopathic ventricular tachycardia (VT) that may be confused with either typical VT or supraventricular tachycardia (SVT). It is characterized by the absence of structural heart disease and classic electrocardiographic and electrophysiological features. It originates from the region of the posterior fascicle (or occasionally the anterior fascicle) of the left bundle branch and is partly propagated by the His-Purkinje network. It therefore produces QRS complexes of relatively short duration (0.11-0.14)s. (NCI)
2009-07-06	20981	C71089	Definition	Misspelling in Definition for 'U Waves' in SDTM-EGSTRESC codelist.	Def: An electrocardiographic finding of a small hump following the T wave occuring during the final phase of Purkinje repolarization. (NCI)	Def: An electrocardiographic finding of a small hump following the T wave occurring during the final phase of Purkinje repolarization. (NCI)
2009-07-06	20982	C71325	Definition	Misspelling in Definition for 'Intermittent' in SDTM-FREQ codelist.	Def: Periodically stoping and starting. (NCI)	Def: Periodically stopping and starting. (NCI)
2009-07-06	20985	C74700	Definition	Misspelling in Definition for 'Bite Cells' in SDTM-LBTEST, SDTM-LBTESTCD codelist.	Def: A measurement of the bite cells (erthrocytes with the appearance of a bite having been removed, due to oxidative hemolysis) in a biological specimen .	Def: A measurement of the bite cells (erythrocytes with the appearance of a bite having been removed, due to oxidative hemolysis) in a biological specimen .
2009-07-06	21561	C70526	Synonym	Incorrect synonym of term 'GBq/ug' transcribed on CDISC CT spreadsheet.	SY: Gigabecquerel per  microgram; MBq/ug, Megabecquerel per microgram	SY: Gigabecquerel per microgram; MBq/ng, Megabecquerel per nanogram