Release Date	Request Code	Change Type	NCI Code	CDISC Term Type	CDISC Codelist (Short Name)	CDISC Codelist (Long Name)	Change Summary	Original	New	Change Implementation Instructions
2021-03-26	CDISC-4578	Add	C177921	Term	GNRLOBSC	General Observation Class	Add new term to existing codelist	- - -	DEVICE LEVEL ANALYSIS DATASET	
2021-03-26	CDISC-4659	Add	C177922	Term	GNRLOBSC	General Observation Class	Add new term to existing codelist	- - -	MEDICAL DEVICE BASIC DATA STRUCTURE	
2021-03-26	CDISC-4660	Add	C177923	Term	GNRLOBSC	General Observation Class	Add new term to existing codelist	- - -	MEDICAL DEVICE OCCURRENCE DATA STRUCTURE	
2021-03-26	CDISC-4661	Add	C177903	CDISC Codelist	MDBDSSC	ADaM Medical Device Basic Data Structure	Addition of new codelist	- - -	MDBDSSC	
2021-03-26	CDISC-4661	Add	C177920	Term	MDBDSSC	ADaM Medical Device Basic Data Structure	Add new term to new codelist	- - -	MEDICAL DEVICE TIME-TO-EVENT	
2021-03-26	CDISC-4781	Add	C17649	Term	ORIGINT	Origin Type	Add new term to existing codelist	- - -	Other	
2021-03-26	CDISC-4781	Remove	C165636	CDISC Codelist	BDSISC	ADaM Integrated Basic Data Structure Subclass	Retire codelist	BDSISC	- - -	
2021-03-26	CDISC-4781	Remove	C165637	Term	BDSISC	ADaM Integrated Basic Data Structure Subclass	Remove term from retired codelist	TIME-TO-EVENT	- - -	
2021-03-26	CDISC-4781	Remove	C132357	Term	GNRLOBSC	General Observation Class	Remove term entirely from codelist	INTEGRATED BASIC DATA STRUCTURE	- - -	
2021-03-26	CDISC-4781	Remove	C132358	Term	GNRLOBSC	General Observation Class	Remove term entirely from codelist	INTEGRATED OCCURRENCE DATA STRUCTURE	- - -	
2021-03-26	CDISC-4781	Remove	C132359	Term	GNRLOBSC	General Observation Class	Remove term entirely from codelist	INTEGRATED SUBJECT LEVEL	- - -	
2021-03-26	CDISC-4781	Update	C103371	CDISC Synonym	GNRLOBSC	General Observation Class	Add new CDISC Synonym	- - -	Basic Data Structure	
2021-03-26	CDISC-4781	Update	C103372	CDISC Synonym	GNRLOBSC	General Observation Class	Add new CDISC Synonym	- - -	Events	
2021-03-26	CDISC-4781	Update	C103373	CDISC Synonym	GNRLOBSC	General Observation Class	Add new CDISC Synonym	- - -	Findings	
2021-03-26	CDISC-4781	Update	C103374	CDISC Synonym	GNRLOBSC	General Observation Class	Add new CDISC Synonym	- - -	Interventions	
2021-03-26	CDISC-4781	Update	C103375	CDISC Synonym	GNRLOBSC	General Observation Class	Add new CDISC Synonym	- - -	ADaM Other	
2021-03-26	CDISC-4781	Update	C103376	CDISC Synonym	GNRLOBSC	General Observation Class	Add new CDISC Synonym	- - -	Relationships	
2021-03-26	CDISC-4781	Update	C103377	CDISC Synonym	GNRLOBSC	General Observation Class	Add new CDISC Synonym	- - -	Special Purpose	
2021-03-26	CDISC-4781	Update	C103378	CDISC Synonym	GNRLOBSC	General Observation Class	Add new CDISC Synonym	- - -	Subject Level Analysis Dataset	
2021-03-26	CDISC-4781	Update	C103379	CDISC Synonym	GNRLOBSC	General Observation Class	Add new CDISC Synonym	- - -	Trial Design	
2021-03-26	CDISC-4781	Update	C123454	CDISC Synonym	GNRLOBSC	General Observation Class	Add new CDISC Synonym	- - -	Occurrence Data Structure	
2021-03-26	CDISC-4781	Update	C135396	CDISC Synonym	GNRLOBSC	General Observation Class	Add new CDISC Synonym	- - -	Findings About	
2021-03-26	CDISC-4781	Update	C147271	CDISC Synonym	GNRLOBSC	General Observation Class	Add new CDISC Synonym	- - -	Study Reference	
2021-03-26	CDISC-4492	Update	C25936	CDISC Definition	ORIGINS	Origin Source	Update CDISC Definition	A person responsible for the conduct of the clinical trial at a trial site. If a trial is conducted by a team of individuals at the trial site, the investigator is the responsible leader of the team and may be called the principle investigator.	A person responsible for the conduct of the clinical trial at a trial site. If a trial is conducted by a team of individuals at the trial site, the investigator is the responsible leader of the team and may be called the principal investigator.