Release Date	Request Code	Change Type	NCI Code	CDISC Term Type	CDISC Codelist (Short Name)	CDISC Codelist (Long Name)	Change Summary	Original	New	Change Implementation Instructions
2020-03-27	CDISC-3494	Add	C170543	Term	DTYPE	Derivation Type	Add new term to existing codelist	- - -	LLOQ	
2020-03-27	CDISC-3634	Add	C170544	Term	DTYPE	Derivation Type	Add new term to existing codelist	- - -	ULOQ	
2020-03-27	CDISC-4206	Add	C170545	Term	DTYPE	Derivation Type	Add new term to existing codelist	- - -	PHANTOM	
2020-03-27	CDISC-3636	Add	C170546	Term	DTYPE	Derivation Type	Add new term to existing codelist	- - -	HALFLLOQ	
2020-03-27	CDISC-4206	Remove	C82866	Term	DTYPE	Derivation Type	Remove term entirely from codelist	ENDPOINT	- - -	Remove C82866 from codelist entirely and instead use one of the other terms within the codelist. Endpoint doesn’t describe how AVAL was derived, which is the scope for this codelist.
2020-03-27	CDISC-4206	Update	C132340	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Best Observed Case: A data imputation technique which populates analysis values with the best outcome recorded within a subject.	A data derivation or imputation technique which sets the analysis value on the record to the best outcome recorded within a subject.	
2020-03-27	CDISC-4206	Update	C132340	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Best Observed Case	
2020-03-27	CDISC-4206	Update	C132341	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Last Observed Value: A data imputation technique which populates analysis values with the subject's last recorded nonmissing observation.	A data derivation or imputation technique which sets the analysis value on the record to the subject's last recorded non-missing observation.	
2020-03-27	CDISC-4206	Update	C132341	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Last Observed Value	
2020-03-27	CDISC-4206	Update	C132342	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Last Value Prior to Dosing: A data imputation technique which populates missing values with the subject's last observed value prior to the start of study treatment.	A data derivation or imputation technique which sets the analysis value on the record to the subject's last observed value prior to the start of study treatment.	
2020-03-27	CDISC-4206	Update	C132342	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Last Value Prior to Dosing	
2020-03-27	CDISC-4206	Update	C132343	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Worst Observed Case: A data imputation technique which populates analysis values with the worst recorded outcome within a subject.	A data derivation or imputation technique which sets the analysis value on the record to the worst recorded outcome within a subject.	
2020-03-27	CDISC-4206	Update	C132343	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Worst Observed Case	
2020-03-27	CDISC-4206	Update	C139176	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	A method of imputation involving populating an analysis value that is outside the range of observed values and is estimated by a function of those observed values.	A data derivation or imputation technique which sets the analysis value on the record to an estimation of a value based on extending a known sequence of values.	
2020-03-27	CDISC-4206	Update	C139176	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Extrapolation	
2020-03-27	CDISC-4114	Update	C158155	CDISC Definition	GDS02PC	Geriatric Depression Scale Short Form Questionnaire Parameter Code	Update CDISC Definition	Geriatric Depression Scale Short Form - Total score.	Geriatric Depression Scale Short Form - Total score used for analysis.	
2020-03-27	CDISC-4114	Update	C158155	CDISC Synonym	GDS02PC	Geriatric Depression Scale Short Form Questionnaire Parameter Code	Add new CDISC Synonym	- - -	GDS02-Total Score - Analysis	
2020-03-27	CDISC-4114	Update	C158155	CDISC Synonym	GDS02PC	Geriatric Depression Scale Short Form Questionnaire Parameter Code	Remove CDISC Synonym	GDS02-Total Score	- - -	
2020-03-27	CDISC-4114	Update	C158155	CDISC Submission Value	GDS02PN	Geriatric Depression Scale Short Form Questionnaire Parameter Name	Update CDISC Submission Value	GDS02-Total Score	GDS02-Total Score - Analysis	
2020-03-27	CDISC-4114	Update	C158155	CDISC Definition	GDS02PN	Geriatric Depression Scale Short Form Questionnaire Parameter Name	Update CDISC Definition	Geriatric Depression Scale Short Form - Total score.	Geriatric Depression Scale Short Form - Total score used for analysis.	
2020-03-27	CDISC-4114	Update	C158155	CDISC Synonym	GDS02PN	Geriatric Depression Scale Short Form Questionnaire Parameter Name	Add new CDISC Synonym	- - -	GDS02-Total Score - Analysis	
2020-03-27	CDISC-4114	Update	C158155	CDISC Synonym	GDS02PN	Geriatric Depression Scale Short Form Questionnaire Parameter Name	Remove CDISC Synonym	GDS02-Total Score	- - -	
2020-03-27	CDISC-4206	Update	C53331	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Maximum Likelihood: A data imputation technique which populates missing values with estimates that maximize the probability of observing what has in fact been observed.	A data derivation or imputation technique which sets the analysis value on the record to the estimate that maximizes the probability of observing what has in fact been observed.	
2020-03-27	CDISC-4206	Update	C53331	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Maximum Likelihood	
2020-03-27	CDISC-4206	Update	C81198	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Last Observation Carried Forward: A data imputation technique which populates missing values with the subject's previous nonmissing value.	A data derivation or imputation technique which sets the analysis value on the record to the subject's previous non-missing value.	
2020-03-27	CDISC-4206	Update	C81198	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Last Observation Carried Forward	
2020-03-27	CDISC-4206	Update	C81199	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Worst Observed Value Carried Forward: A data imputation technique which populates missing values with the subject's worst-case nonmissing observation.	A data derivation or imputation technique which sets the analysis value on the record to the subject's worst-case non-missing observation.	
2020-03-27	CDISC-4206	Update	C81199	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Worst Observed Value Carried Forward	
2020-03-27	CDISC-4206	Update	C81200	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Screening Observation Carried Forward: A data imputation technique which populates missing values with the subject's nonmissing screening observation.	A data derivation or imputation technique which sets the analysis value on the record to the subject's non-missing screening observation.	
2020-03-27	CDISC-4206	Update	C81200	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Screening Observation Carried Forward	
2020-03-27	CDISC-4206	Update	C81201	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Baseline Observation Carried Forward: A data imputation technique which populates missing values with the subject's nonmissing baseline observation.	A data derivation or imputation technique which sets the analysis value on the record to the subject's non-missing baseline observation.	
2020-03-27	CDISC-4206	Update	C81201	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Baseline Observation Carried Forward	
2020-03-27	CDISC-4206	Update	C81203	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Worst Case: A data imputation technique which populates analysis values with the worst possible outcome.	A data derivation or imputation technique which sets the analysis value on the record to the worst possible outcome.	
2020-03-27	CDISC-4206	Update	C81203	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Worst Case	
2020-03-27	CDISC-4206	Update	C81204	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Mean of Other Group: A data imputation technique which populates missing values with the mean value from a comparator or reference group.	A data derivation or imputation technique which sets the analysis value on the record to the mean value from a comparator or reference group.	
2020-03-27	CDISC-4206	Update	C81204	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Mean of Other Group	
2020-03-27	CDISC-4206	Update	C81205	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Penultimate Observation Carried Forward: A data imputation technique which populates missing values with the subject's next-to-last nonmissing value.	A data derivation or imputation technique which sets the analysis value on the record to the subject's next-to-last non-missing value.	
2020-03-27	CDISC-4206	Update	C81205	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Penultimate Observation Carried Forward	
2020-03-27	CDISC-4206	Update	C81206	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Worst Observed Value in a Group: A data imputation technique which populates missing values with the worst value observed in a group of subjects.	A data derivation or imputation technique which sets the analysis value on the record to the worst value observed in a group of subjects.	
2020-03-27	CDISC-4206	Update	C81206	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Worst Observed Value in a Group	
2020-03-27	CDISC-4206	Update	C81207	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Mean Observed Value in a Group: A data imputation technique which populates missing values with the mean value observed in a group of subjects.	A data derivation or imputation technique which sets the analysis value on the record to the mean value observed in a group of subjects.	
2020-03-27	CDISC-4206	Update	C81207	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Mean Observed Value in a Group	
2020-03-27	CDISC-4206	Update	C81208	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Interpolation: A method of imputation involving a missing value that is between known values and is estimated by a function of those known values.	A data derivation or imputation technique which sets the analysis value on the record to a function of known values to estimate a value within the range.	
2020-03-27	CDISC-4206	Update	C81208	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Interpolation	
2020-03-27	CDISC-4206	Update	C81209	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Average: A data derivation technique which calculates a subject's average value over a defined set of records.	A data derivation or imputation technique which sets the analysis value on the record to the subject's average value over a defined set of records.	
2020-03-27	CDISC-4206	Update	C81209	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Average	
2020-03-27	CDISC-4206	Update	C82867	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Minimum: A technique which populates an analysis value with a subject's minimum value over a defined set of records.	A data derivation or imputation technique which sets the analysis value on the record to the subject's minimum value over a defined set of records.	
2020-03-27	CDISC-4206	Update	C82867	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Minimum	
2020-03-27	CDISC-4206	Update	C82868	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Maximum: A technique which populates an analysis value with a subject's maximum value over a defined set of records.	A data derivation or imputation technique which sets the analysis value on the record to the subject's maximum value over a defined set of records.	
2020-03-27	CDISC-4206	Update	C82868	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Maximum	
2020-03-27	CDISC-4206	Update	C92225	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Best Case: A data imputation technique which populates missing values with the best possible outcome.	A data derivation or imputation technique which sets the analysis value on the record to the best possible outcome.	
2020-03-27	CDISC-4206	Update	C92225	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Best Case	
2020-03-27	CDISC-4206	Update	C92226	CDISC Definition	DTYPE	Derivation Type	Update CDISC Definition	Best Observation Carried Forward: A data imputation technique which populates missing values with the subject's previous best-case nonmissing value.	A data derivation or imputation technique which sets the analysis value on the record to the subject's previous best-case non-missing value.	
2020-03-27	CDISC-4206	Update	C92226	CDISC Synonym	DTYPE	Derivation Type	Add new CDISC Synonym	- - -	Best Observation Carried Forward