Subset Code Subset Preferred Term Concept Code NCIt Preferred Term NCIt Definition ICDC Preferred Term ICDC Synonym CDISC Preferred Term Has ICDC Value Code ICDC PT for Has ICDC Value C166371 ICDC Data Model Terminology C175518 ICDC Node Terminology Terminology that supports the study nodes in the Integrated Canine Data Commons (ICDC) data model. node C166371 ICDC Data Model Terminology C166373 ICDC Property Terminology Terminology representing the data properties collected by the Integrated Canine Data Commons (ICDC). property C166371 ICDC Data Model Terminology C175517 ICDC Value Terminology Terminology that supports the values associated with data properties in the Integrated Canine Data Commons (ICDC) data model. value_or_Type value or Type C175518 ICDC Node Terminology C41331 Adverse Event Any unfavorable or unintended disease, sign, or symptom (including an abnormal laboratory finding) that is temporally associated with the use of a medical treatment or procedure, and that may or may not be considered related to the medical treatment or procedure. Such events can be related to the intervention, dose, route of administration, patient, or caused by an interaction with another drug(s) or procedure(s). adverse_event adverse event ADVERSE EVENT C175518 ICDC Node Terminology C1708 Agent An active power or cause (as principle, substance, physical or biological factor, etc.) that produces a specific effect. agent C175518 ICDC Node Terminology C70962 Agent Administration The act of the dispensing, applying, or tendering a medical product or other agent. agent_administration agent administration C175518 ICDC Node Terminology C60819 Assay A qualitative or quantitative analysis performed to determine the amount of a particular constituent in a sample or the biological or pharmacological properties of a drug. assay C175518 ICDC Node Terminology C48800 Biorepository A storage facility of biospecimens that includes tissue samples, fluids, and molecular derivatives such as DNA, RNA, and proteins. The biorepository has stringent guidelines regarding the standardized collection, handling, storage, and documentation of biological specimens. biospecimen_source biospecimen source C175518 ICDC Node Terminology C70699 Biospecimen Any material sample taken from a biological entity for testing, diagnostic, propagation, treatment or research purposes, including a sample obtained from a living organism or taken from the biological object after halting of all its life functions. Biospecimen can contain one or more components including but not limited to cellular molecules, cells, tissues, organs, body fluids, embryos, and body excretory products. sample BIOSPECIMEN || Biological Sample C175518 ICDC Node Terminology C183326 Canine Study Subject A canine about whom research data is obtained through intervention or interaction with or through use of historical medical data or other identifiable private information. canine_individual canine individual C175518 ICDC Node Terminology C49152 Case A problem requiring investigation. case C175518 ICDC Node Terminology C15206 Clinical Study Research conducted with human subjects or on material of human origin in which an investigator directly interacts with human subjects; includes development of new technologies, study of mechanisms of human diseases, therapy, clinical trials, epidemiologic, behavior, and health services research. study Clinical Study || Clinical Study C175518 ICDC Node Terminology C70777 Clinical Study Site A healthcare organization, an institution, a facility, a healthcare provider, or a part or a constituent of any of the above entities directly involved in conducting a particular clinical study. study_site study site CLINICAL STUDY SITE C175518 ICDC Node Terminology C61512 Cohort A group of individuals, identified by a common characteristic. cohort C175518 ICDC Node Terminology C25472 Cycle An event or sequence of events that constitute a round or succession of observable phenomena, recurring usually at regular or approximately regular time intervals and in the same sequence. cycle C175518 ICDC Node Terminology C142508 Demographic Data Aspects of individuals or groups of individuals in a study, including basic descriptive information like age and sex. demographic C175518 ICDC Node Terminology C15220 Diagnosis The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation. diagnosis DIAGNOS || DIAGNOSIS || DIAGNOSIS || Diagnosis || Diagnosis C175518 ICDC Node Terminology C37948 Enrollment The act of registration, entering in a list, catalog, group, study; also, the number of subjects enrolled. enrollment C175518 ICDC Node Terminology C42883 File A set of related records (either written or electronic) kept together. file C175518 ICDC Node Terminology C16033 Follow-Up The process by which information about the health status of an individual is obtained after a study has officially closed; an activity that continues something that has already begun or that repeats something that has already been done. follow_up follow up CLSFUP || Clinical Signs Follow-up C175518 ICDC Node Terminology C48179 Image Any record of an imaging event whether physical or electronic. image C175518 ICDC Node Terminology C183327 Image Set A set of images that are stored together due to their shared association with an institution, investigator, experiment, investigation, study or trial. image_collection image collection C175518 ICDC Node Terminology C25294 Laboratory Procedure Any procedure that involves testing or manipulating a sample of blood, urine, or other body substance in a laboratory setting. lab_exam lab exam C175518 ICDC Node Terminology C63409 Lead Organization The principal administrative organization responsible for the research conducted. program C175518 ICDC Node Terminology C174125 Neoplastic Disease Extent Indicator An indication of whether a neoplastic disease has extended beyond its anatomic site of origin. disease_extent disease extent C175518 ICDC Node Terminology C29851 Off Study No longer participating in a study; not being followed and will not be retreated. off_study off study C175518 ICDC Node Terminology C25601 Off Treatment When a patient is not receiving therapy they are considered off treatment. In clinical trials, a dosing schedule may require a patient to stop medication for a period of time, then resume, such as 28 days on and 7 days off. off_treatment off treatment C175518 ICDC Node Terminology C39564 Patient Visit A visit by a patient or study participant to a medical professional. visit C175518 ICDC Node Terminology C20989 Physical Examination A systemic evaluation of the body and its functions using visual inspection, palpation, percussion and auscultation. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment. physical_exam physical exam PHYSICAL EXAM || PHYSICAL EXAMINATION || PHYSICAL EXAMINATION || PHYSICAL EXAMINATION C175518 ICDC Node Terminology C19924 Principal Investigator An investigator who is responsible for all aspects of the conduct of a study. principal_investigator principal investigator PRINCIPAL INVESTIGATOR || PRINCIPAL INVESTIGATOR || Principal Investigator C175518 ICDC Node Terminology C16169 Prior Surgery An indication that a subject has had a surgical procedure in the past. prior_surgery prior surgery C175518 ICDC Node Terminology C16124 Prior Therapy Prior action or administration of therapeutic agents that produced an effect that is intended to alter or stop a pathologic process. prior_therapy prior therapy C175518 ICDC Node Terminology C15538 Protocol Treatment Arm A specific treatment plan within a clinical trial that describes the activities a subject will be involved in as he or she progresses through the study. study_arm study arm Treatment Arm C175518 ICDC Node Terminology C48471 Publication A printed or electronic work offered for distribution. publication C175518 ICDC Node Terminology C25646 Registration The act of listing or recording officially; officially qualified or enrolled. registration C175518 ICDC Node Terminology C154628 Vital Signs Vital signs (such as height, weight, and blood pressure) directly measure an individual's current state of attributes. vital_signs vital signs C166373 ICDC Property Terminology C93495 Acronym The non-unique initials or abbreviated name used for identification. program_acronym program acronym C166373 ICDC Property Terminology C164321 Adverse Event Agent Name The name of a therapeutic agent considered to be causally linked to an adverse event. ae_agent_name ae agent name C166373 ICDC Property Terminology C166260 Adverse Event Attributed to Commercial Product An indication that an adverse event is causally related to the use of a commercially available product. attribution_to_commercial attribution to commercial C166373 ICDC Property Terminology C166261 Adverse Event Attributed to Disease An indication that an adverse event is causally related to the natural history of disease. attribution_to_disease attribution to disease C166373 ICDC Property Terminology C166262 Adverse Event Attributed to Investigational New Drug An indication that an adverse event is causally related to the use of an investigational new drug (IND). attribution_to_ind attribution to ind C166373 ICDC Property Terminology C166263 Adverse Event Attributed to Other Cause An indication that an adverse event is causally related to an entity that is a not a disease- or research-related process nor a commercial product or investigational new drug (IND). attribution_to_other attribution to other C166373 ICDC Property Terminology C166264 Adverse Event Attributed to Research An indication that an adverse event is causally related to processes a subject was exposed to during a research study. attribution_to_research attribution to research C166373 ICDC Property Terminology C164319 Adverse Event Dose The dose of a therapeutic agent considered to be causally linked to an adverse event. ae_dose ae dose C166373 ICDC Property Terminology C164318 Adverse Event Grade Description A textual description of the grade of an adverse event. adverse_event_grade_description adverse event grade description C166373 ICDC Property Terminology C93718 Adverse Event Resolution Date The date (and time) when the adverse event ends or returns to baseline. date_resolved date resolved C166373 ICDC Property Terminology C166200 Adverse Event Severity Grade A numeric value corresponding to the degree of severity of an adverse event. adverse_event_grade adverse event grade C166373 ICDC Property Terminology C164320 Adverse Event Term A term that refers to an adverse event, often taken from a list of standardized terms. adverse_event_term adverse event term C166373 ICDC Property Terminology C78541 Adverse Event Verbatim Description The verbatim description of the adverse event. adverse_event_description adverse event description AETERM C166373 ICDC Property Terminology C164338 Age of Enrollment The age of a subject when entering a group, catalog, list, or study. patient_age_at_enrollment patient age at enrollment C166373 ICDC Property Terminology C166199 Agent Unit of Measure The unit of measure that is associated with an agent for administration. agent_units_of_measure agent units of measure C166373 ICDC Property Terminology C166205 Area of Analysis The total area of a sample that is used for analysis. analysis_area analysis area C166373 ICDC Property Terminology C93728 Arm Description The textual representation of the arm. This is a description of the pathway followed by all subjects in a particular treatment regimen. arm_description arm description Study Arm Description || Study Arm Description C166373 ICDC Property Terminology C94536 Best Overall Response The most clinically favorable response recorded from the start of the study treatment until the end of treatment. best_response best response BESTRESP || Best Overall Response C17998 || C18058 || C18213 || C35571 || C48660 || C4870 || C67119 Unknown || Partial Response || Stable Disease || Progressive Disease || Not Applicable || Complete Response || Not Determined C166373 ICDC Property Terminology C168625 Best Overall Response Registered from Start of Therapy to a Time Point of Interest The most clinically favorable response recorded from the start of the treatment until a specified time point in a study. best_resp_vet_tx_tp_best_response best resp vet tx tp best response C166373 ICDC Property Terminology C168626 Best Secondary Endpoint Response Registered from Start of Therapy to a Time Point of Interest The most favorable response measured for a secondary endpoint recorded from the start of the treatment until a specified time point in a study. best_resp_vet_tx_tp_secondary_response best resp vet tx tp secondary response C166373 ICDC Property Terminology C94173 Biologic Entity Birth Date The date (and time) on which the biologic entity is born. date_of_birth date of birth C166373 ICDC Property Terminology C64262 Biologic Sample Preservation Procedure Procedures utilized to save organic substances from decay. Some preservation procedures are meant to maintain cells, tissues, or organisms in a viable state. sample_preservation sample preservation C143028 || C17998 || C48660 || C63521 FFPE || Unknown || Not Applicable || Snap Frozen C166373 ICDC Property Terminology C175250 Biospecimen Collection Chronology The temporal relationship between the collection of biological sample and a clinical milestone. sample_chronology sample chronology C175242 || C175243 || C175244 || C17998 || C48660 || C54734 || C54735 || C94193 During Treatment || Upon Progression || Upon Relapse || Unknown || Not Applicable || Before Treatment || After Treatment || Upon Death C166373 ICDC Property Terminology C184811 Biospecimen Repository Acronym The acronym associated with the biospecimen repository which samples were acquired from or submitted to. biospecimen_repository_acronym biospecimen repository acronym C166373 ICDC Property Terminology C184810 Biospecimen Repository Name The name of the biospecimen repository which samples were acquired from or submitted to. biospecimen_repository_full_name biospecimen repository full name C166373 ICDC Property Terminology C70713 Biospecimen Type The type of a material sample taken from a biological entity for testing, diagnostic, propagation, treatment or research purposes. This includes particular types of cellular molecules, cells, tissues, organs, body fluids, embryos, and body excretory substances. physical_sample_type physical sample type SPEC C16403 || C17610 || C19697 Cell Line || Blood || Tissue C166373 ICDC Property Terminology C25157 Body Surface Area A measure of the 2-dimensional extent of the body surface (i.e., the skin). Body surface area (BSA) can be calculated by mathematical formula or from a chart that relates height to weight. BSA is often an important factor in dosing. body_surface_area body surface area BSA || Body Surface Area C166373 ICDC Property Terminology C174446 Body Temperature A measurement of the temperature of the body. body_temperature body temperature TEMP || Temperature C166373 ICDC Property Terminology C81328 Body Weight The weight of a subject. patient_weight patient weight || weight BW || Body Weight C166373 ICDC Property Terminology C183330 Canine Subject Unique Identifier A unique identifier for a canine clinical subject. canine_individual_id canine individual id C166373 ICDC Property Terminology C164324 Case Identifier A unique alphanumeric identifier assigned to a specific case. case_id case id C166373 ICDC Property Terminology C164327 Case Report Form Identifier A unique alphanumeric identifier assigned to a specific case report form. crf_id crf id C166373 ICDC Property Terminology C166254 Change Since Last Physical Exam Changes from the previous physical examination that are noted during the current physical examination. physical_exam_changes physical exam changes C166373 ICDC Property Terminology C166206 Chemotherapeutic Cycle End Date The date on which a chemotherapeutic cycle is ended. date_of_cycle_end date of cycle end C166373 ICDC Property Terminology C166208 Chemotherapeutic Cycle Number The number of the individual chemotherapeutic cycle. cycle_number cycle number C166373 ICDC Property Terminology C166207 Chemotherapeutic Cycle Start Date The date on which a chemotherapeutic cycle is started. date_of_cycle_start date of cycle start C166373 ICDC Property Terminology C183331 Clinical Cohort Unique Identifier A unique identifier for a clinical cohort. cohort_id cohort id C166373 ICDC Property Terminology C70730 Clinical Study Population Subgroup Relatively uniform groups (e.g. etiologically and pathogenetically more homogeneous, racial, ethnic, or gender-specific, or the disease- or condition-specific) of study subjects formed within a clinical study population for a separate analysis. The selection of the subgroups, methods of subgroup analysis, and anticipated difference in observation outcome(s) have to be defined and justified in the study protocol and based on known biological mechanisms, and/or findings in previous studies. patient_subgroup patient subgroup C166373 ICDC Property Terminology C183325 Clinical Subject Initials The first letter of each word in the name of a clinical subject. initials C166373 ICDC Property Terminology C166209 Cohort Description The description of the characteristics that define a cohort. cohort_description cohort description C166373 ICDC Property Terminology C166210 Cohort Dose The dose of medication administered to a particular cohort. cohort_dose cohort dose C166373 ICDC Property Terminology C81286 Collection Date The date on which the sample or data was collected. date_of_sample_collection date of sample collection C166373 ICDC Property Terminology C25393 Comment A written explanation, observation or criticism added to textual material. comment C166373 ICDC Property Terminology C161320 Comorbid Condition Medical or health condition that is concomitant or concurrent with the primary condition or disease under study. concurrent_disease concurrent disease Comorbid Condition C17998 || C49487 || C49488 Unknown || No || Yes C166373 ICDC Property Terminology C164326 Concurrent Disease Type The classification and naming of comorbid conditions. concurrent_disease_type concurrent disease type C17998 || C49487 || C49488 Unknown || No || Yes C166373 ICDC Property Terminology C94394 Cumulative Dose The total amount of an agent (e.g., drug, biologic, radiation, etc.) administered to a subject over a defined period of time. total_dose total dose C166373 ICDC Property Terminology C166220 Date Off Treatment The date on which a subject is no longer receiving therapy. date_off_treatment date off treatment C166373 ICDC Property Terminology C166218 Date of Best Response The date on which the best response to therapy was observed and recorded. date_of_best_response date of best response C166373 ICDC Property Terminology C164339 Date of Diagnosis The date on which a diagnosis of disease was made. date_of_diagnosis date of diagnosis C166373 ICDC Property Terminology C166219 Date of Disease Progression The date on which disease progression was observed and recorded. date_of_disease_progression date of disease progression C166373 ICDC Property Terminology C164340 Date of Evaluation The date on which an evaluation was performed. date_of_evaluation date of evaluation C166373 ICDC Property Terminology C164328 Date of First Dose The date on which the first dose of a specified treatment regiment was administered. date_of_first_dose date of first dose C166373 ICDC Property Terminology C156819 Date of Last Administration The date of the last administration of the substance of interest. date_last_medication_administration date last medication administration C166373 ICDC Property Terminology C156916 Date of Last Contact The date of the last contact. date_of_last_contact date of last contact C166373 ICDC Property Terminology C164329 Date of Last Dose The date on which the last dose of a specified treatment regiment was administered. date_of_last_dose date of last dose C166373 ICDC Property Terminology C164342 Date of Last NSAID Administration The date on which a patient last received an NSAID. date_of_last_dose_nsaid date of last dose nsaid C166373 ICDC Property Terminology C164343 Date of Last Steroid Administration The date on which a patient last received steroid. date_of_last_dose_steroid date of last dose steroid C166373 ICDC Property Terminology C156814 Date of Last Therapy The date of the last radiation treatment, chemotherapy, molecular targeted therapy, or immunotherapy treatment. date_of_last_dose_any_therapy date of last dose any therapy C166373 ICDC Property Terminology C166253 Date of Missed Dose Specifies the date of a missed dose of a therapeutic agent. date_of_missed_dose date of missed dose C166373 ICDC Property Terminology C159308 Date of Surgical Procedure A question about the date on which a surgical procedure was performed. date_of_surgery date of surgery C166373 ICDC Property Terminology C71462 Digital Object Identifier A unique code used by publishers in the identification and exchange of the content of a digital object, such as a journal article, web document, or other item of intellectual property. The DOI consists of two parts: a prefix assigned to each publisher by the administrative DOI agency and a suffix assigned by the publisher that may be any code the publisher chooses. digital_object_id digital object id C166373 ICDC Property Terminology C28076 Disease Grade Qualifier A term that refers to the cellular differentiation of a malignant cellular infiltrate. A cancer is defined through grades I-IV (or 1-4), or as well, moderately, poorly differentiated or undifferentiated. tumor_grade tumor grade C14158 || C14161 || C17998 || C28077 || C28078 || C28079 || C28082 || C28083 || C48660 High || Low || Unknown || 1 || 2 || 3 || 4 || Medium || Not Applicable C166373 ICDC Property Terminology C185941 Disease Molecular Subtype Qualifier A term or phrase used to specify or describe a disease subtype based on its molecular signature. molecular_subtype molecular subtype C166373 ICDC Property Terminology C28108 Disease Stage Qualifier An adjectival term that can specify or describe a disease stage. stage_of_disease stage of disease C17998 || C186460 || C186461 || C186462 || C186463 || C186464 || C186465 || C186466 || C186467 || C186468 || C186470 || C186471 || C186472 || C48660 || C67119 Unknown || I || Ia || Ib || II || IIa || IIb || III || IIIa || IIIb || IV || IVa || IVb || Not Applicable || Not Determined C166373 ICDC Property Terminology C2991 Disease or Disorder Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function. disease_term disease term C166373 ICDC Property Terminology C93399 Document Identifier The unique identification of a document in a specified context. document_number document number C166373 ICDC Property Terminology C53693 Dog Breed A type of dog known for its special or distinctive characteristics. breed C166373 ICDC Property Terminology C25488 Dose A quantity of an agent (such as substance or energy) administered, taken, or absorbed at one time. dose_level dose level DOSE || DOSE || Dose || Dose Level || Dose per Administration || TRTDOS C166373 ICDC Property Terminology C167190 Dose Administered A quantity of an agent given to an individual at one time. medication_actual_dose medication actual dose C166373 ICDC Property Terminology C71137 Dose Regimen A treatment plan that specifies the amount, schedule, and the duration of intervention(s). dose_schedule dose schedule DOSRGM || DOSRGM || Dose Regimen C166373 ICDC Property Terminology C166259 Dose Unit of Measure The unit of measure that is associated with the dose of a substance administered to the subject. dose_units_of_measure dose units of measure C166373 ICDC Property Terminology C164322 Drug Name The identifier or name of a therapeutic agent. agent_name agent name C166373 ICDC Property Terminology C83168 Duration of Use The amount of time that a thing is consumed or employed. medication_duration medication duration CDUR C166373 ICDC Property Terminology C41328 Electrocardiographic Finding Graphic representation and categorization of the electrical vectors produced by the depolarization and repolarization of myocardial tissue. ecg C166373 ICDC Property Terminology C172272 Electronic File Content Type The nature of the content stored in an electronic file. file_type file type C171178 || C172215 || C172216 || C172880 || C175233 || C175234 || C175239 || C175245 || C175246 || C175247 || C183341 || C183342 || C28277 || C70817 Variant Report || Mutation Annotation File || Variant Call File || Index File || RNA Sequence File || Whole Exome Sequence File || Whole Genome Sequence File || DNA Methylation Analysis File || Image File || Supplemental Data File || Array CGH Analysis File || Data Analysis Whitepaper || Pathology Report || pathology_report || Study Protocol C166373 ICDC Property Terminology C171190 Electronic File Description A free text field that can be used to document details about an electronic file that may not be captured elsewhere. file_description file description C166373 ICDC Property Terminology C171252 Electronic File Format The format of an electronic file. file_format file format C166373 ICDC Property Terminology C171191 Electronic File Name The literal identifier for an electronic file. file_name file name C166373 ICDC Property Terminology C171192 Electronic File Size The size of an electronic file. file_size file size C166373 ICDC Property Terminology C171193 Electronic File Status The condition for an electronic file relative to the current data or file processing step. file_status file status C172861 || C172862 || C172863 || C172864 || C172865 || C172866 || C172867 || C172868 || C172869 || C172870 || C172871 || C172872 || C172876 uploading || uploaded || md5summing || md5summed || validating || error || invalid || suppressed || redacted || live || validated || submitted || released C166373 ICDC Property Terminology C82573 End Time The time when an event has ceased. stop_time stop time ENTIM C166373 ICDC Property Terminology C166224 Enrollment Document Number The identifier assigned to an enrollment document. enrollment_document_number enrollment document number C166373 ICDC Property Terminology C166226 Evaluation Code The code assigned to an evaluation. evaluation_code evaluation code C166373 ICDC Property Terminology C166227 Evaluation Sequence Number The number assigned to an evaluation, indicating where a particular evaluation falls within a sequence of multiple evaluations. evaluation_number evaluation number C166373 ICDC Property Terminology C40974 First Name A word or group of words indicating a person's first (personal or given) name; the name that precedes the surname. pi_first_name pi first name C166373 ICDC Property Terminology C156846 Follow-Up Information Information regarding the follow-up period. follow_up_data follow up data C49487 || C49488 No || Yes C166373 ICDC Property Terminology C166228 Follow-Up Type of Contact A description of the type of interaction that occurs between provider and subject during the follow-up period. contact_type contact type C166373 ICDC Property Terminology C166265 Histologic Confirmation Date The date that a histological diagnosis was confirmed. date_of_histology_confirmation date of histology confirmation C166373 ICDC Property Terminology C18000 Histologic Grade The degree of abnormality of cancer cells, a measure of differentiation, the extent to which cancer cells are similar in appearance and function to healthy cells of the same tissue type. The degree of differentiation often relates to the clinical behavior of the particular tumor. Based on the microscopic findings, tumor grade is commonly described by one of four degrees of severity. Histopathologic grade of a tumor may be used to plan treatment and estimate the future course, outcome, and overall prognosis of disease. Certain types of cancers, such as soft tissue sarcoma, primary brain tumors, lymphomas, and breast have special grading systems. histological_grade histological grade OVLTGRD || Overall Tumor Grade C166373 ICDC Property Terminology C166230 Histopathology-Cytopathology Indicator An indicator denoting whether a diagnosis was assigned based on histopathology or cytopathology. histology_cytopathology histology cytopathology C166373 ICDC Property Terminology C166268 How was the Extent of Disease Measured A question pertaining to how the extent of a disease or lesion was measured. measured_how measured how C166373 ICDC Property Terminology C168629 ICDC Program Sort Order A value assigned by the Integrated Canine Data Commons (ICDC) that indicates where a particular project is located in the list of all of the projects included in ICDC. program_sort_order program sort order C166373 ICDC Property Terminology C168630 ICDC Study Identifier A unique alphanumeric code assigned to a project by the Integrated Canine Data Commons (ICDC) that includes an abbreviation representing the project's sponsor organization. clinical_study_designation clinical study designation C166373 ICDC Property Terminology C183328 ICDC Study/Trial Accession Identifier A unique, alpha-numeric identifier comprised of "ICDC" followed by six digits, which can be resolved by identifiers.org and is assigned to the study/trial as it is on-boarded. accession_id accession id C166373 ICDC Property Terminology C171437 ICDC Summarized Sample Type Indicator An ICDC property that specifies the combined data that indicates the type (tissue, blood, cells, etc.), normal or tumor origin and derivation from a primary tumor or metastatic lesion for a sample. summarized_sample_type summarized sample type C166373 ICDC Property Terminology C183338 Image Repository Name The name of the imaging data repository. repository_name repository name C166373 ICDC Property Terminology C183333 Image Set Access Method Indicator An enumeration of the methods by which a user can obtain an image set. collection_access collection access C183343 || C183344 Cloud || Download C166373 ICDC Property Terminology C183332 Image Set Name The name of a set of images stored together. image_collection_name image collection name C166373 ICDC Property Terminology C183334 Image Set URL A URL-formatted web address for a set of images stored together. image_collection_url image collection url C166373 ICDC Property Terminology C69268 Image Type A category of image. image_type_included image type included C166373 ICDC Property Terminology C93579 Informed Consent Date The date (and time) the patient gives consent to a surgical or medical procedure or participation in a clinical study after achieving an understanding of the relevant medical facts and the risks involved. date_of_informed_consent date of informed consent C166373 ICDC Property Terminology C41206 Institution An established society, corporation, foundation or other organization founded and united for a specific purpose, e.g. for health-related research; also used to refer to a building or buildings occupied or used by such organization. registering_institution registering institution INSTITUTION C166373 ICDC Property Terminology C166266 Institutional Animal Care and Use Committee Approval Date The date that the Institutional Animal Care and Use Committee (IACUC) approved an animal study protocol. This date cannot be released to funding agencies until congruency between the animal use in the funding proposal and the IACUC approved protocol has been verified. date_of_iacuc_approval date of iacuc approval C166373 ICDC Property Terminology C25218 Intervention or Procedure An activity that produces an effect, or that is intended to alter the course of a disease in a patient or population. This is a general term that encompasses the medical, social, behavioral, and environmental acts that can have preventive, therapeutic, or palliative effects. procedure Intervention C166373 ICDC Property Terminology C174266 Investigational Arm An arm describing the intervention or treatment plan for a group of participants in the study receiving test product(s). arm Experimental Arm C166373 ICDC Property Terminology C183336 Journal Citation A bibliographical reference to a cited journal article. journal_citation journal citation C166373 ICDC Property Terminology C40975 Last Name A word or group of words indicating a person's last (family) name. pi_last_name pi last name C166373 ICDC Property Terminology C166231 Lesion Description Specifies the description of a localized pathological or traumatic structural change, damage, deformity, or discontinuity of tissue, organ, or body part. lesion_description lesion description C166373 ICDC Property Terminology C93587 Lesion Number The integer assigned to a localized pathological or traumatic structural change, damage, deformity, or discontinuity of tissue, organ or body part. lesion_number lesion number C166373 ICDC Property Terminology C166232 Lesion Site Specifies the anatomic site of a localized pathological or traumatic structural change, damage, deformity, or discontinuity of tissue, organ, or body part. lesion_site lesion site C166373 ICDC Property Terminology C96684 Longest Diameter The longest possible length of a straight line passing through the center of a circular or spheroid object that connects two points on the circumference. longest_measurement longest measurement LDIAM || LDIAM || LDIAM || LDIAM || LDIAM || Longest Diameter || Longest Diameter || Longest Diameter || Longest Diameter || Longest Diameter C166373 ICDC Property Terminology C70848 Lot Number A distinctive alpha-numeric identification code assigned by the manufacturer or distributor to a specific quantity of manufactured material or product within a batch. medication_lot_number medication lot number LOT || LOT || Lot Number C166373 ICDC Property Terminology C171276 MD5 Checksum A 32-character hexadecimal number that is computed on a file. md5sum C166373 ICDC Property Terminology C167209 Measurable Lesion A finding indicating that a localized pathological lesion can be measured in at least one dimension. measurable_lesion measurable lesion C166373 ICDC Property Terminology C459 Medication A drug product that contains one or more active and/or inactive ingredients; it is intended to treat, prevent or alleviate the symptoms of disease. This term does not refer to the individual ingredients that make up the product. medication C166373 ICDC Property Terminology C166233 Medication Acutal Unit of Measure The actual unit of measure used to quantify an administered dose of a therapeutic agent to a subject. medication_actual_units_of_measure medication actual units of measure C166373 ICDC Property Terminology C166235 Medication Course Number The number assigned to a course of therapeutic agent administration, indicating where a particular course of treatment falls within a sequence of treatments. medication_course_number medication course number C166373 ICDC Property Terminology C192240 Medication Dose Unit of Measure The unit of measure that is associated with the dose of an administered medicine. medication_units_of_measure medication units of measure C166373 ICDC Property Terminology C166236 Medication Vial Identifier An identifier associated with a particular vial of medication. medication_vial_id medication vial id C166373 ICDC Property Terminology C166237 Middle Initial The first letter of a person's middle name. pi_middle_initial pi middle initial C166373 ICDC Property Terminology C50429 Missed Dose A dose of medicine that was not taken at the prescribed dosing interval. missed_dose_amount missed dose amount C166373 ICDC Property Terminology C166234 Missed Dose Unit of Measure The unit of measure used to quantify a missed dose of a therapeutic agent to a subject. missed_dose_units_of_measure missed dose units of measure C166373 ICDC Property Terminology C166269 Missed Medication Dose Name The name of the medication that was not taken when a dose was missed. medication_missed_dose medication missed dose C166373 ICDC Property Terminology C164330 Modified ECOG Performance Status A version of the ECOG performance status scale for use in canines. modified_ecog modified ecog C166373 ICDC Property Terminology C164333 NSAID Total Dose The total number of doses of NSAIDs given in a given period of time. total_number_of_doses_nsaid total number of doses nsaid C166373 ICDC Property Terminology C166270 Necropsy Sample A biospecimen collected during the surgical examination of a dead body. necropsy_sample necropsy sample C17998 || C48660 || C49487 || C49488 Unknown || Not Applicable || No || Yes C166373 ICDC Property Terminology C158349 Neutered Indicator An indication as to whether the animal(s) has been neutered. neutered_indicator neutered indicator NEUTIND || Neutered Indicator C17998 || C49487 || C49488 Unknown || No || Yes C166373 ICDC Property Terminology C166238 Non-Tumor Tissue Area The area within a sample that is represented by non-tumor tissue. non_tumor_tissue_area non tumor tissue area C166373 ICDC Property Terminology C166271 Non-responsive Therapy Type The categorization of the treatment that was administered to a subject that did not produce the intended (therapeutic) effect. nonresponse_therapy_type nonresponse therapy type C166373 ICDC Property Terminology C166229 Normal or Tumor Sample Pathology Indicator Specifies whether a sample is derived from normal or tumor-bearing tissue. general_sample_pathology general sample pathology C12801 || C14143 || C14172 || C175249 || C3113 || C48660 Normal || Malignant || Benign || Diseased || Hyperplastic || Not Applicable C166373 ICDC Property Terminology C166241 Number of Prior Regimens A number that identifies the number of prior cycles of any therapy a subject has received. number_of_prior_regimens_any_therapy number of prior regimens any therapy C166373 ICDC Property Terminology C166242 Number of Prior Regimens of NSAID A number that identifies the number of prior cycles of NSAID therapy a subject has received. number_of_prior_regimens_nsaid number of prior regimens nsaid C166373 ICDC Property Terminology C166243 Number of Prior Regimens of Steroids A number that identifies the number of prior cycles of steroid therapy a subject has received. number_of_prior_regimens_steroid number of prior regimens steroid C166373 ICDC Property Terminology C93610 Off Study Date The date (and time) when the study subject is removed from the study. date_off_study date off study C166373 ICDC Property Terminology C12919 Organ System An anatomical structure that consists of organs and organ subclasses responsible for certain body functions. Representative examples are the gastrointestinal system, urinary system, and hematopoietic system. body_system body system C12378 || C12686 || C12705 || C12746 || C12754 || C12755 || C12810 || C12841 || C12907 || C16326 || C17649 || C42300 Gastrointestinal || Cardiovascular || Endocrine || Lymphatic || Musculoskeletal || Neurologic || Genitourinary || Integumentary || Attitude || Other || Eyes/Ears/Nose/Throat C166373 ICDC Property Terminology C47922 Pathname The specification of a node (file or directory) in a hierarchical file system, usually specified by listing the nodes top-down. file_location file location C166373 ICDC Property Terminology C28277 Pathology Report A report that provides a description of the gross and microscopic examination of the specimen and is used to make a diagnosis and to determine treatment. It defines which structures and organs of the body are involved by the tumor, verifies the primary site of the cancer and describes the extent to which it has spread. pathology_report pathology report C49487 || C49488 No || Yes C166373 ICDC Property Terminology C164337 Patient Identifier An alphanumeric identifier assigned to a specific patient. patient_id patient id C166373 ICDC Property Terminology C166244 Patient Status An indicator that provides information on the current health status of a patient. patient_status patient status C166373 ICDC Property Terminology C166202 Percent Pigmented Tumor in Analysis Area The area of a sample on a slide that is represented by pigmented tumor tissue, which will be analyzed. analysis_area_percentage_pigmented_tumor analysis area percentage pigmented tumor C166373 ICDC Property Terminology C166203 Percent Stroma in Analysis Area The percentage of the analysis area that is represented by stromal tissue. analysis_area_percentage_stroma analysis area percentage stroma C166373 ICDC Property Terminology C166245 Percent Stromal Tissue The percentage of stromal tissue in a sample. percentage_stroma percentage stroma C166373 ICDC Property Terminology C166246 Percent Tumor Tissue The percentage of tumor tissue in a sample. percentage_tumor percentage tumor C166373 ICDC Property Terminology C166204 Percent Tumor in Analysis Area The percentage of the analysis area that is represented by tumor tissue. analysis_area_percentage_tumor analysis area percentage tumor C166373 ICDC Property Terminology C166201 Percent of Glass in Analysis Area The area of a sample on a slide that is represented by glass; the area of the sample that represents gaps in the sample. analysis_area_percentage_glass analysis area percentage glass C166373 ICDC Property Terminology C93620 Period Dose Total Total of all doses of treatment in a given period of time. total_number_of_doses_any_therapy total number of doses any therapy C166373 ICDC Property Terminology C25257 Phase A distinguishable part, a stage in a series of events or in a process of development, e.g. any of the varying aspects or stages in course of a disease; a fraction of a cycle. phase C166373 ICDC Property Terminology C113376 Physical Exam Performed An indication or description that a subject physical examination test has occurred. physical_exam_performed physical exam performed PEPERF C166373 ICDC Property Terminology C166247 Physical Examination Comment A field for use to add comments regarding a physical examination. pe_comment pe comment C166373 ICDC Property Terminology C83030 Physical Examination Date The date that the physical examination occurred on. date_of_examination date of examination PEDAT C166373 ICDC Property Terminology C83119 Physical Examination Finding The result of an evaluation of the body and its functions using visual inspection, palpation, percussion, or auscultation that is performed to determine the presence, absence, or degree of a condition. pe_finding pe finding PERES C166373 ICDC Property Terminology C81297 Point in Time Test Given The hour, minute, and/or second that an examination was administered. assessment_timepoint assessment timepoint C166373 ICDC Property Terminology C158874 Primary Site of Disease The anatomic location where a disease of interest originated. primary_disease_site primary disease site C166373 ICDC Property Terminology C166248 Prior NSAID Exposure Indicator Specifies wheter a subject has had prior exposure to NSAID. prior_nsaid_exposure prior nsaid exposure C166373 ICDC Property Terminology C15477 Prior Radiation Therapy An indicator that a person previously received radiation treatment for the same condition. previously_irradiated previously irradiated C166373 ICDC Property Terminology C166249 Prior Steroid Exposure Indicator Specifies wheter a subject has had prior exposure to steroids. prior_steroid_exposure prior steroid exposure C166373 ICDC Property Terminology C16124 Prior Therapy Prior action or administration of therapeutic agents that produced an effect that is intended to alter or stop a pathologic process. previously_treated previously treated C166373 ICDC Property Terminology C166250 Prior Therapy Type Specifies the type of prior therapy. prior_therapy_type prior therapy type C166373 ICDC Property Terminology C166272 Program External URL A URL address for a research program or study that is accessible by those outside the host institution. program_external_url program external url C166373 ICDC Property Terminology C166273 Program Full Description An unabridged description of a research program or study. program_full_description program full description C166373 ICDC Property Terminology C166274 Program Name The name applied to a research program or study. program_name program name C166373 ICDC Property Terminology C166275 Program Short Description An abbreviated description of a research program or study. program_short_description program short description C166373 ICDC Property Terminology C171181 Protocol Treatment Arm Unique Identifier A unique identifier assigned to a protocol treatment arm. arm_id arm id C166373 ICDC Property Terminology C127797 PubMed Unique Identifier A globally unique identifier for a biomedical article, as assigned by PubMed. pubmed_id pubmed id PUBMEDID || PubMed ID for Citation Used in Study C166373 ICDC Property Terminology C183329 Publication Citation Author List A list of authors cited for a published work. authorship C166373 ICDC Property Terminology C183337 Publication Title The title for a published article. publication_title publication title C166373 ICDC Property Terminology C183340 Publication Year The year in which a document was published. year_of_publication year of publication C166373 ICDC Property Terminology C25749 Pulse The rhythmic wave within the arteries occurring with each contraction of the left ventricle. pulse C166373 ICDC Property Terminology C38085 Pulse Oximetry A non-invasive method that provides estimates of arterial oxyhemoglobin saturation by utilizing selected wavelengths of light to determine the saturation of oxyhemoglobin. pulse_ox pulse ox PULSE OXIMETRY C166373 ICDC Property Terminology C166276 Reason Off Treatment The reason the administration of a drug or therapeutic procedure was interrupted or stopped. reason_off_treatment reason off treatment C166373 ICDC Property Terminology C49627 Reason for Study Discontinuation The reason that a subject was discontinued from a study. reason_off_study reason off study Reason for Study Discontinuation C166373 ICDC Property Terminology C123282 Regimen-Limiting Toxicity A side effect of a drug or other treatment that is serious enough to necessitate a dose modification. dose_limiting_toxicity dose limiting toxicity C166373 ICDC Property Terminology C4809 Residual Disease Tumor cells that remain in the body following cancer treatment. residual_disease residual disease C166373 ICDC Property Terminology C164331 Respiratory Pattern A description of the breathing cycle at a point in time, which is informed by the rate, depth, and regularity of respiration. respiration_pattern respiration pattern C166373 ICDC Property Terminology C49678 Respiratory Rate The rate of breathing (inhalation and exhalation) measured within in a unit time, usually expressed as breaths per minute. respiration_rate respiration rate RESP || RESPRATE || Respiratory Rate || Respiratory Rate C166373 ICDC Property Terminology C38114 Route of Administration Designation of the part of the body through which or into which, or the way in which, the medicinal product is intended to be introduced. In some cases a medicinal product can be intended for more than one route and/or method of administration. route_of_administration route of administration ROUTE || ROUTE || ROUTE || Route of Administration || Route of Administration || Route of Administration C166373 ICDC Property Terminology C171435 Sample Anatomic Site The anatomic site from which a biospecimen was obtained. sample_site sample site C166373 ICDC Property Terminology C171436 Sample Pathology Indicator Specifies the pathologic process or disease associated with a sample. specific_sample_pathology specific sample pathology C166373 ICDC Property Terminology C28421 Sex The assemblage of physical properties or qualities by which male is distinguished from female; the physical difference between male and female; the distinguishing peculiarity of male or female. sex SEX C17998 || C46112 || C46113 Unknown || Male || Female C166373 ICDC Property Terminology C166277 Short Site Name The abbreviation or abridged identifier representing the place hosting a research program or study. site_short_name site short name C166373 ICDC Property Terminology C168623 Specify Other Adverse Event A directive to identify the cause of an adverse event when the listed responses are not applicable. ae_other ae other C166373 ICDC Property Terminology C166393 Specimen Identifier A unique alphanumeric identifier assigned to a specimen. sample_id sample id C166373 ICDC Property Terminology C78441 Start Time The time at which something is to start or did start. start_time start time STTIM C166373 ICDC Property Terminology C164334 Steroid Total Dose The total number of doses of steroids given in a given period of time. total_number_of_doses_steroid total number of doses steroid C166373 ICDC Property Terminology C142701 Study Branch A planned point in time within the study design in which there is a subdivision of subjects to particular procedures or treatment groups. arm C166373 ICDC Property Terminology C166251 Study Conduct Date Range The date range that encompasses the dates that a study was performed. dates_of_conduct dates of conduct C166373 ICDC Property Terminology C183339 Study Data Status Disposition Indicator An indication of the status of study data deposited in a database. study_disposition study disposition C183345 || C183346 || C53470 Under Embargo || Unrestricted || Pending C166373 ICDC Property Terminology C142704 Study Description Specific, essential aspects of an investigation that are detailed, including structure, blinding, dosage, and participant demographics. clinical_study_description clinical study description C166373 ICDC Property Terminology C83082 Study Identifier A sequence of characters used to identify, name, or characterize the study. clinical_study_id clinical study id STUDYID || STUDYID || Study Identifier || Study Identifier C166373 ICDC Property Terminology C68631 Study Name The name applied to a scientific investigation. clinical_study_name clinical study name C166373 ICDC Property Terminology C93681 Study Registration Date The date (and time) the subject has been registered to the study. date_of_registration date of registration C166373 ICDC Property Terminology C142175 Study Type The nature of the investigation or the investigational use for which the study is being done. clinical_study_type clinical study type STYPE || Study Type || Study Type || Study Type Classification C166373 ICDC Property Terminology C83083 Subject Identifier A sequence of characters used to identify, name, or characterize a trial or study subject. registration_id registration id SUBJID C166373 ICDC Property Terminology C94160 Subject Identifier Primary Indicator Specifies whether this is the main or principal subject identifier. is_primary_id is primary id C49487 || C49488 No || Yes C166373 ICDC Property Terminology C175531 Subject Identifier Source The identifier for the entity that is associated with a subject identifier. registration_origin registration origin C166373 ICDC Property Terminology C69257 Subject Name The name of the individual of interest. patient_first_name patient first name C166373 ICDC Property Terminology C164341 Surgical Finding A finding or observation that is made during surgery. surgical_finding surgical finding C166373 ICDC Property Terminology C164323 Surgical Site The anatomical site on which surgery was performed. anatomical_site_of_surgery anatomical site of surgery C166373 ICDC Property Terminology C25298 Systolic Blood Pressure The maximum pressure exerted into the systemic arterial circulation during the contraction of the left ventricle of the heart. systolic_bp systolic bp SYSBP || SYSBP || Systolic Blood Pressure || Systolic Blood Pressure C166373 ICDC Property Terminology C94520 Target Lesion Identification The identification of a lesion that is present at baseline, is measurable and is the primary target of the therapeutic intervention. target_lesion target lesion TARGET C166373 ICDC Property Terminology C168631 Therapeutic Indicator An indication as to whether a specified treatment has been administered to a subject. therapeutic_indicator therapeutic indicator C166373 ICDC Property Terminology C49236 Therapeutic Procedure An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process. any_therapy any therapy C166373 ICDC Property Terminology C157518 Therapy Used Since Last Visit An indication of the type of therapy used since the last visit. treatment_since_last_contact treatment since last contact C166373 ICDC Property Terminology C157517 Therapy Used at Visit An indication of the type of therapy used during a visit. therapy_type therapy type C166373 ICDC Property Terminology C166239 Total Sample Tissue Area The total area of a tissue sample. total_tissue_area total tissue area C166373 ICDC Property Terminology C165236 Treatment Assignment Code An identification code assigned to each unique treatment regimen to uniformly group patients for separate analysis of adverse events and response data. ctep_treatment_assignment_code ctep treatment assignment code C166373 ICDC Property Terminology C166221 Treatment Cycle Day Number A number that indicates the position of a day within a treatment cycle. day_in_cycle day in cycle C166373 ICDC Property Terminology C164335 Treatment Data Data pertaining to the medical or surgical treatment of a patient. treatment_data treatment data C49487 || C49488 No || Yes C166373 ICDC Property Terminology C171433 Treatment Performed at Study Site Indicator Specifies whether treatment was administered to a subject at a study site. treatment_performed_at_site treatment performed at site C166373 ICDC Property Terminology C171434 Treatment Performed in Measurable Residual Disease Indicator Specifies whether a treatment was administered to a subject that was diagnosed with minimal residual disease. treatment_performed_in_minimal_residual treatment performed in minimal residual C166373 ICDC Property Terminology C200479 Tumor Length The longest perpendicular diameter of a tumor. length_of_tumor length of tumor C166373 ICDC Property Terminology C171438 Tumor Sample Origin Indicator Specifies whether a sample was derived from a primary tumor versus a metastatic lesion. tumor_sample_origin tumor sample origin C156440 || C17998 || C48660 || C8509 Metastatic || Unknown || Not Applicable || Primary C166373 ICDC Property Terminology C166240 Tumor Tissue Area The area within a sample that is comprised of tumor tissue. tumor_tissue_area tumor tissue area C166373 ICDC Property Terminology C94515 Tumor Volume The volume of tumor. volume_of_tumor volume of tumor C166373 ICDC Property Terminology C200480 Tumor Width The longest diameter of a tumor. width_of_tumor width of tumor C166373 ICDC Property Terminology C41334 Unexpected Adverse Event Any adverse event associated with a medical product or procedure that has not been previously observed, whether or not the event was anticipated because of the pharmacologic properties of the study agent or the nature of the medical procedure. This includes events that are more serious than expected or occur more frequently than expected, particularly, any adverse experience, the nature, severity or frequency of which is not consistent with the product label, or with the current investigator brochure for investigational agent; or with the risk information described in the investigational plan or protocol or consent form. unexpected_adverse_event unexpected adverse event unexpected adverse drug reaction C166373 ICDC Property Terminology C54100 Universally Unique Identifier A 128 bit identifier. Depending on the mechanism used to generate it, it is either guaranteed to be different from all other UUIDs/GUIDs generated until 3400 AD or extremely likely to be different. Its relatively small size lends itself well to sorting, ordering, and hashing of all sorts, storing in databases, simple allocation, and ease of programming in general. uuid C166373 ICDC Property Terminology C166267 Unknown Status Reason An explanation of why the status of a subject is unknown. explain_unknown_status explain unknown status C166373 ICDC Property Terminology C164336 Veterinary Medical Center A veterinary institution that provides medical or surgical care and treatment for the sick or the injured. veterinary_medical_center veterinary medical center C166373 ICDC Property Terminology C83031 Visit Date The date on which a visit occurred. visit_date visit date VISDAT C166373 ICDC Property Terminology C83101 Visit Number The numerical identifier of the visit. visit_number visit number C166373 ICDC Property Terminology C83032 Vital Signs Date The date on which a vital signs assessment is carried out. date_of_vital_signs date of vital signs VSDAT C175517 ICDC Value Terminology C183344 Available by Download Data or documents are able to be downloaded. Download C175517 ICDC Value Terminology C183343 Available on the Cloud Data or documents are able to be accessed via a cloud server. Cloud C175517 ICDC Value Terminology C16326 Behavior The actions or reactions of an object or organism, usually in relation to the environment or surrounding world of stimuli. Attitude C175517 ICDC Value Terminology C14172 Benign For neoplasms, a non-infiltrating and non-metastasizing neoplastic process that is characterized by the absence of morphologic features associated with malignancy (e.g., severe atypia, nuclear pleomorphism, tumor cell necrosis, and abnormal mitoses). For other conditions, a process that is mild in nature and not dangerous to health. Benign BENIGN C175517 ICDC Value Terminology C17610 Blood Sample A small volume of blood removed for testing or storage. Blood C175517 ICDC Value Terminology C186460 Canine Neoplasm Stage I A canine neoplasm that is confined to the primary site. I C175517 ICDC Value Terminology C186463 Canine Neoplasm Stage II A canine neoplasm that is invasive and may have spread to local lymph nodes. II C175517 ICDC Value Terminology C186466 Canine Neoplasm Stage III A canine neoplasm that has spread to one or more local sites or organs. III C175517 ICDC Value Terminology C186467 Canine Neoplasm Stage IIIa A canine neoplasm that has spread to one or more local sites or organs, without systemic symptoms. IIIa C175517 ICDC Value Terminology C186468 Canine Neoplasm Stage IIIb A canine neoplasm that has spread to one or more local sites or organs, with systemic symptoms. IIIb C175517 ICDC Value Terminology C186464 Canine Neoplasm Stage IIa A canine neoplasm that is confined to the primary site, without systemic symptoms. IIa C175517 ICDC Value Terminology C186465 Canine Neoplasm Stage IIb A canine neoplasm that is invasive and may have spread to local lymph nodes with systemic symptoms. IIb C175517 ICDC Value Terminology C186470 Canine Neoplasm Stage IV A canine neoplasm with distant metastasis or a recurrent neoplasm. IV C175517 ICDC Value Terminology C186471 Canine Neoplasm Stage IVa A canine neoplasm with distant metastasis or a recurrent neoplasm, without systemic symptoms. IVa C175517 ICDC Value Terminology C186472 Canine Neoplasm Stage IVb A canine neoplasm with distant metastasis or a recurrent neoplasm, with systemic symptoms. IVb C175517 ICDC Value Terminology C186461 Canine Neoplasm Stage Ia A canine neoplasm that is confined to the primary site, without systemic symptoms. Ia C175517 ICDC Value Terminology C186462 Canine Neoplasm Stage Ib A canine neoplasm that is confined to the primary site, with systemic symptoms. Ib C175517 ICDC Value Terminology C12686 Cardiovascular System Relating to the heart and the blood vessels or the circulation. Cardiovascular CARDIOVASCULAR SYSTEM C175517 ICDC Value Terminology C16403 Cell Line A permanently established cell culture that will proliferate indefinitely given appropriate fresh medium and space. Cell Line C175517 ICDC Value Terminology C183341 Comparative Genomic Hybridization Array Data Analysis File An electronic file containing data related to comparative genomic hybridization array analysis. Array CGH Analysis File C175517 ICDC Value Terminology C4870 Complete Remission The disappearance of all signs of cancer in response to treatment. Complete Response CR C175517 ICDC Value Terminology C175245 DNA Methylation Analysis Data File An electronic file containing data related to DNA methylation analysis. DNA Methylation Analysis File C175517 ICDC Value Terminology C183342 Data Analysis Whitepaper An informational document describing a data analysis process. Data Analysis Whitepaper C175517 ICDC Value Terminology C12378 Digestive System The system that includes the esophagus, stomach, small and large intestine, anus, liver, biliary tract, and pancreas. Gastrointestinal GASTROINTESTINAL SYSTEM C175517 ICDC Value Terminology C175249 Diseased An indication that an anatomic structure has detectable aberrations. Diseased C175517 ICDC Value Terminology C175242 During Treatment Occurring during the time that a subject received treatment. During Treatment C175517 ICDC Value Terminology C12705 Endocrine System Collective designation for those tissues capable of secreting hormones. Endocrine C175517 ICDC Value Terminology C46113 Female Phenotype An animal who is observed by researcher or clinician to be female, the sex that ordinarily produces ova. Female FEMALE C175517 ICDC Value Terminology C172865 File Being Validated An indication that a file is in the process of being validated by a data repository. validating C175517 ICDC Value Terminology C172869 File Redacted An indication that a submitted file or the data within a file has been redacted before or during submission to a data repository. redacted C175517 ICDC Value Terminology C172872 File Submitted An indication that a file has been submitted to a data repository. submitted C175517 ICDC Value Terminology C172868 File Suppressed An indication that a submitted file has been suppressed from the view of the users for a data repository. suppressed C175517 ICDC Value Terminology C172862 File Uploaded An indication that a submitted file has successfully been uploaded to a data repository. uploaded C175517 ICDC Value Terminology C172861 File Uploading An indication that a submitted file is in the process of being uploaded to a data repository. uploading C175517 ICDC Value Terminology C172871 File Validated An indication that a file has successfully completed the validation process for submission into a data repository. validated C175517 ICDC Value Terminology C172866 File in Error An indication that an error occurred during the submission of a file to a data repository. error C175517 ICDC Value Terminology C143028 Formalin-Fixed Paraffin-Embedded Refers to a process where a sample is preserved with formalin and then embedded into a paraffin block for sectioning. FFPE C175517 ICDC Value Terminology C12810 Genitourinary System The body system that includes all organs involved in reproduction and in the formation and voidance of urine. Genitourinary GENITOURINARY SYSTEM C175517 ICDC Value Terminology C28077 Grade 1 A morphologic qualifier indicating that a cancerous lesion is well differentiated. 1 GRADE 1 C175517 ICDC Value Terminology C28078 Grade 2 A morphologic qualifier indicating that a cancerous lesion is moderately differentiated. 2 GRADE 2 C175517 ICDC Value Terminology C28079 Grade 3 A morphologic qualifier indicating that a cancerous lesion is poorly differentiated. 3 GRADE 3 C175517 ICDC Value Terminology C28082 Grade 4 A morphologic qualifier indicating that a cancerous lesion is undifferentiated. 4 GRADE 4 C175517 ICDC Value Terminology C42300 Head, Ears, Eyes, Nose and Throat HEENT is the Head, Ears, Eyes, Nose and Throat, and is referred to as a body system on a physical or medical examination. The term is typically used as 'HEENT' in a physician or caregiver notes. Eyes/Ears/Nose/Throat C175517 ICDC Value Terminology C14158 High Grade Used to describe tumor samples that exhibit poorly differentiated or undifferentiated cells. They are generally expected to be fast growing and aggressive. High C175517 ICDC Value Terminology C3113 Hyperplasia An abnormal increase in the number of cells in an organ or a tissue with consequent enlargement. Hyperplastic HYPERPLASIA C175517 ICDC Value Terminology C175246 Image File An electronic file containing imaging data. Image File C175517 ICDC Value Terminology C172880 Index File An electronic file that documents the names and types of all the files associated with an operating system or a data set (i.e. files related to a sample, case or study, etc.). Index File C175517 ICDC Value Terminology C12907 Integumentary System The enveloping membrane of the body; includes, in addition to the epidermis and dermis, all the derivatives of the epidermis, e.g., hairs, nails, sudoriferous and sebaceous glands. Integumentary C175517 ICDC Value Terminology C28083 Intermediate Grade A term referring to the degree of differentiation of a malignant neoplasm and indicating that it is moderately differentiated. Medium C175517 ICDC Value Terminology C172867 Invalid File An indication that a file has invalid data or is in an invalid format and cannot be submitted to a data repository. invalid C175517 ICDC Value Terminology C172870 Live File An indication that a file is active within a data repository. live C175517 ICDC Value Terminology C14161 Low Grade Used to describe tumor samples that exhibit well to moderately well differentiated cells. They are generally expected to be slow growing and less aggressive. Low C175517 ICDC Value Terminology C12746 Lymphatic System The anatomic system that includes the lymph nodes, lymphoid tissues in various organs (spleen, thymus, tonsils, gastrointestinal tract), and lymphatic vessels. It is part of the immune system that offers protection against infections. Lymphatic C175517 ICDC Value Terminology C46112 Male Phenotype An animal who is observed by researcher or clinician to be male, the sex that ordinarily produces sperm. Male MALE C175517 ICDC Value Terminology C14143 Malignant Refers to abnormal cell activity manifested by decreased control over growth and function, causing tumor growth or spread into surrounding tissue and adverse effects to the host. Malignant MALIGNANT C175517 ICDC Value Terminology C172864 Md5 Checksum Completed An indication that a submitted file has successfully been assigned an md5 checksum. md5summed C175517 ICDC Value Terminology C172863 Md5 Checksumming An indication that a submitted file is in the process of being assigned an md5 checksum. md5summing C175517 ICDC Value Terminology C156440 Metastatic Tumor Sample A biospecimen derived from a metastatic tumor. Metastatic C175517 ICDC Value Terminology C12754 Musculoskeletal System The system of muscles, tendons, ligaments, bones, joints and associated tissues that move the body and maintain its form. Musculoskeletal MUSCULOSKELETAL SYSTEM C175517 ICDC Value Terminology C172215 Mutation Annotation Format A tab-delimited text file containing mutation information aggregated from variant call files (VCF) across a project, trial or study. Mutation Annotation File C175517 ICDC Value Terminology C12755 Nervous System The entire nerve apparatus, composed of a central part, the brain and spinal cord, and a peripheral part, the cranial and spinal nerves, autonomic ganglia, and plexuses. Neurologic C175517 ICDC Value Terminology C49487 No The non-affirmative response to a question. No N C175517 ICDC Value Terminology C48660 Not Applicable Determination of a value is not relevant in the current context. Not Applicable NA || NA || NOT APPLICABLE || NOT APPLICABLE || NOT APPLICABLE || Not Applicable C175517 ICDC Value Terminology C67119 Not Ascertained Not learned, discovered, or determined with certainty. Not Determined C175517 ICDC Value Terminology C17649 Other Different than the one(s) previously specified or mentioned. Other OTHER || OTHER || OTHER || OTHER || OTHER || OTHER || OTHER || OTHER || Other || Other C175517 ICDC Value Terminology C18058 Partial Remission A finding indicating that there is a decrease in the size and the extent of tissue involvement by a malignant tumor in a patient. Partial Response PR C175517 ICDC Value Terminology C28277 Pathology Report A report that provides a description of the gross and microscopic examination of the specimen and is used to make a diagnosis and to determine treatment. It defines which structures and organs of the body are involved by the tumor, verifies the primary site of the cancer and describes the extent to which it has spread. Pathology Report C175517 ICDC Value Terminology C53470 Pending Not yet decided or settled; awaiting conclusion or confirmation. Pending C175517 ICDC Value Terminology C54735 Post-Therapy Occurring after a therapeutic procedure. After Treatment C175517 ICDC Value Terminology C94193 Postmortem Occurring after death. Upon Death C175517 ICDC Value Terminology C54734 Pre-Therapy Occurring before a therapeutic procedure. Before Treatment C175517 ICDC Value Terminology C8509 Primary Neoplasm A tumor at the original site of origin. Primary C175517 ICDC Value Terminology C35571 Progressive Disease A clinical, pathologic, and/or molecular finding indicating that the course of a disease is worsening in terms of extent or severity. Progressive Disease PD || PROGRESSIVE DISEASE C175517 ICDC Value Terminology C63521 Quick Freeze To freeze rapidly so as to preserve structure and prevent ice crystal formation. Snap Frozen FLASH FREEZING C175517 ICDC Value Terminology C175233 RNA Sequencing Data File An electronic file containing ribonucleic acid (RNA) sequencing data. RNA Sequence File C175517 ICDC Value Terminology C172876 Released File An indication that a file has been released to the users of a database or data repository. released C175517 ICDC Value Terminology C12779 Respiratory System The organs involved in the exchange of carbon dioxide and oxygen including the trachea, bronchi, and lung parenchyma. Respiratory RESPIRATORY SYSTEM C175517 ICDC Value Terminology C171178 Sequence Variant Report A short document listing the sequence variants found in a sample. Variant Report C175517 ICDC Value Terminology C18213 Stable Disease A disease that is neither decreasing nor increasing in extent or severity. Stable Disease SD C175517 ICDC Value Terminology C70817 Study Protocol The formal plan of an experiment or research activity, including the objective, rationale, design, materials and methods for the conduct of the study; intervention description, and method of data analysis. Study Protocol Study Protocol C175517 ICDC Value Terminology C175247 Supplemental Data File An electronic file containing supplemental data. Supplemental Data File C175517 ICDC Value Terminology C12801 Tissue An anatomical structure consisting of similarly specialized cells and intercellular matrix, aggregated according to genetically determined spatial relationships, performing a specific function. Normal TISSUE C175517 ICDC Value Terminology C19697 Tissue Sample A piece of tissue removed from an organism for examination, analysis, or propagation. Tissue C175517 ICDC Value Terminology C183345 Under Embargo Information that will not be published until a predetermined condition is met. Under Embargo C175517 ICDC Value Terminology C17998 Unknown Not known, observed, recorded; or reported as unknown by the data contributor. Unknown U || U || U || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN || UNKNOWN C175517 ICDC Value Terminology C183346 Unrestricted Access Information that is public and can be used freely. Unrestricted C175517 ICDC Value Terminology C175243 Upon Progression Occurring after a subject experienced disease progression. Upon Progression C175517 ICDC Value Terminology C175244 Upon Relapse Occurring after a subject experienced disease relapse. Upon Relapse C175517 ICDC Value Terminology C172216 Variant Call File Format A text-based electronic file used for storing gene sequence variation data. The first text section is composed of a header containing the metadata and keywords used in the file. This is followed by the body of the file which is tab-separated into eight mandatory data columns for each sample. Additionally, the body of the file can include an unlimited number of optional columns to record other sample-related data. Variant Call File C175517 ICDC Value Terminology C175234 Whole Exome Sequencing Data File An electronic file containing data collected during whole exome sequencing. Whole Exome Sequence File C175517 ICDC Value Terminology C175239 Whole Genome Sequencing Data File An electronic file containing data collected during whole genome sequencing. Whole Genome Sequence File C175517 ICDC Value Terminology C49488 Yes The affirmative response to a question. Yes Y