A C175518 ICDC Node Terminology C48800 Biorepository A storage facility of biospecimens that includes tissue samples, fluids, and molecular derivatives such as DNA, RNA, and proteins. The biorepository has stringent guidelines regarding the standardized collection, handling, storage, and documentation of biological specimens. biospecimen_source biospecimen source C C175518 ICDC Node Terminology C16124 Prior Therapy Prior action or administration of therapeutic agents that produced an effect that is intended to alter or stop a pathologic process. prior_therapy prior therapy A C166373 ICDC Property Terminology C185941 Disease Molecular Subtype Qualifier A term or phrase used to specify or describe a disease subtype based on its molecular signature. molecular_subtype molecular subtype A C166373 ICDC Property Terminology C28076 Disease Grade Qualifier A term that refers to the cellular differentiation of a malignant cellular infiltrate. A cancer is defined through grades I-IV (or 1-4), or as well, moderately, poorly differentiated or undifferentiated. tumor_grade tumor grade C14158 || C14161 || C17998 || C28077 || C28078 || C28079 || C28082 || C28083 || C48660 High || Low || Unknown || 1 || 2 || 3 || 4 || Medium || Not Applicable C C166373 ICDC Property Terminology C94536 Best Overall Response The most clinically favorable response recorded from the start of the study treatment until the end of treatment. best_response best response BESTRESP || Best Overall Response C17998 || C18058 || C18213 || C35571 || C48660 || C4870 || C67119 Unknown || Partial Response || Stable Disease || Progressive Disease || Not Applicable || Complete Response || Not Determined C C166373 ICDC Property Terminology C16124 Prior Therapy Prior action or administration of therapeutic agents that produced an effect that is intended to alter or stop a pathologic process. previously_treated previously treated C C166373 ICDC Property Terminology C28108 Disease Stage Qualifier An adjectival term that can specify or describe a disease stage. stage_of_disease stage of disease C17998 || C186460 || C186461 || C186462 || C186463 || C186464 || C186465 || C186466 || C186467 || C186468 || C186470 || C186471 || C186472 || C48660 || C67119 Unknown || I || Ia || Ib || II || IIa || IIb || III || IIIa || IIIb || IV || IVa || IVb || Not Applicable || Not Determined C C166373 ICDC Property Terminology C28277 Pathology Report A report that provides a description of the gross and microscopic examination of the specimen and is used to make a diagnosis and to determine treatment. It defines which structures and organs of the body are involved by the tumor, verifies the primary site of the cancer and describes the extent to which it has spread. pathology_report pathology report C49487 || C49488 No || Yes A C175517 ICDC Value Terminology C14158 High Grade Used to describe tumor samples that exhibit poorly differentiated or undifferentiated cells. They are generally expected to be fast growing and aggressive. High A C175517 ICDC Value Terminology C14161 Low Grade Used to describe tumor samples that exhibit well to moderately well differentiated cells. They are generally expected to be slow growing and less aggressive. Low A C175517 ICDC Value Terminology C186460 Canine Neoplasm Stage I A canine neoplasm that is confined to the primary site. I A C175517 ICDC Value Terminology C186461 Canine Neoplasm Stage Ia A canine neoplasm that is confined to the primary site, without systemic symptoms. Ia A C175517 ICDC Value Terminology C186462 Canine Neoplasm Stage Ib A canine neoplasm that is confined to the primary site, with systemic symptoms. Ib A C175517 ICDC Value Terminology C186463 Canine Neoplasm Stage II A canine neoplasm that is invasive and may have spread to local lymph nodes. II A C175517 ICDC Value Terminology C186464 Canine Neoplasm Stage IIa A canine neoplasm that is confined to the primary site, without systemic symptoms. IIa A C175517 ICDC Value Terminology C186465 Canine Neoplasm Stage IIb A canine neoplasm that is invasive and may have spread to local lymph nodes with systemic symptoms. IIb A C175517 ICDC Value Terminology C186466 Canine Neoplasm Stage III A canine neoplasm that has spread to one or more local sites or organs. III A C175517 ICDC Value Terminology C186467 Canine Neoplasm Stage IIIa A canine neoplasm that has spread to one or more local sites or organs, without systemic symptoms. IIIa A C175517 ICDC Value Terminology C186468 Canine Neoplasm Stage IIIb A canine neoplasm that has spread to one or more local sites or organs, with systemic symptoms. IIIb A C175517 ICDC Value Terminology C186470 Canine Neoplasm Stage IV A canine neoplasm with distant metastasis or a recurrent neoplasm. IV A C175517 ICDC Value Terminology C186471 Canine Neoplasm Stage IVa A canine neoplasm with distant metastasis or a recurrent neoplasm, without systemic symptoms. IVa A C175517 ICDC Value Terminology C186472 Canine Neoplasm Stage IVb A canine neoplasm with distant metastasis or a recurrent neoplasm, with systemic symptoms. IVb A C175517 ICDC Value Terminology C28077 Grade 1 A morphologic qualifier indicating that a cancerous lesion is well differentiated. 1 GRADE 1 A C175517 ICDC Value Terminology C28078 Grade 2 A morphologic qualifier indicating that a cancerous lesion is moderately differentiated. 2 GRADE 2 A C175517 ICDC Value Terminology C28079 Grade 3 A morphologic qualifier indicating that a cancerous lesion is poorly differentiated. 3 GRADE 3 A C175517 ICDC Value Terminology C28082 Grade 4 A morphologic qualifier indicating that a cancerous lesion is undifferentiated. 4 GRADE 4 A C175517 ICDC Value Terminology C28083 Intermediate Grade A term referring to the degree of differentiation of a malignant neoplasm and indicating that it is moderately differentiated. Medium C C175517 ICDC Value Terminology C28277 Pathology Report A report that provides a description of the gross and microscopic examination of the specimen and is used to make a diagnosis and to determine treatment. It defines which structures and organs of the body are involved by the tumor, verifies the primary site of the cancer and describes the extent to which it has spread. Pathology Report