Code Codelist Code Codelist Extensible (Yes/No) Codelist Name CDISC Submission Value CDISC Synonym(s) CDISC Definition NCI Preferred Term C81223 No Date Imputation Flag DATEFL Date Imputation Flag Date Imputation Flag: Indicates the level of imputation reflected in a date value. CDISC ADaM Date Imputation Flag Terminology C81212 C81223 Date Imputation Flag D Day Imputed: Day is imputed. Day Imputed C81211 C81223 Date Imputation Flag M Month Imputed: Month and day are imputed. Month Day Imputed C81210 C81223 Date Imputation Flag Y Year Imputed: Entire date (year, month and day) is imputed. Year Month Day Imputed C81224 Yes Derivation Type DTYPE Derivation Type Derivation Type: Analysis value derivation method. CDISC ADaM Derivation Type Terminology C81209 C81224 Derivation Type AVERAGE Average A data derivation or imputation technique which sets the analysis value on the record to the subject's average value over a defined set of records. Average of Value Derivation Technique C92225 C81224 Derivation Type BC Best Case A data derivation or imputation technique which sets the analysis value on the record to the best possible outcome. Best Case Imputation Technique C81201 C81224 Derivation Type BLOCF Baseline Observation Carried Forward A data derivation or imputation technique which sets the analysis value on the record to the subject's non-missing baseline observation. Baseline Observation Carried Forward Imputation Technique C132340 C81224 Derivation Type BOC Best Observed Case A data derivation or imputation technique which sets the analysis value on the record to the best outcome recorded within a subject. Best Observed Case Imputation Technique C92226 C81224 Derivation Type BOCF Best Observation Carried Forward A data derivation or imputation technique which sets the analysis value on the record to the subject's previous best-case non-missing value. Best Observation Carried Forward Imputation Technique C184383 C81224 Derivation Type COPY A technique that uses assignment logic to duplicate an analysis value to be used in additional evaluations. Copy Duplication Imputation Technique C139176 C81224 Derivation Type EXTRAP Extrapolation A data derivation or imputation technique which sets the analysis value on the record to an estimation of a value based on extending a known sequence of values. Extrapolation Imputation Technique C170546 C81224 Derivation Type HALFLLOQ One Half of Lower Limit of Quantification A data derivation or imputation technique which sets the analysis value on the record to one half of the lower limit of quantification of a test. One Half of Lower Limit of Quantification Derivation Technique C81208 C81224 Derivation Type INTERP Interpolation A data derivation or imputation technique which sets the analysis value on the record to a function of known values to estimate a value within the range. Interpolation Imputation Technique C105701 C81224 Derivation Type LLOD Lower Limit of Detection A data derivation or imputation technique which sets the analysis value on the record to the lower limit of detection of a test. Detection Limit C170543 C81224 Derivation Type LLOQ Lower Limit of Quantification A data derivation or imputation technique which sets the analysis value on the record to the lower limit of quantification of a test. Lower Limit of Quantification Derivation Technique C81198 C81224 Derivation Type LOCF Last Observation Carried Forward A data derivation or imputation technique which sets the analysis value on the record to the subject's previous non-missing value. Last Observation Carried Forward Imputation Technique C132341 C81224 Derivation Type LOV Last Observed Value A data derivation or imputation technique which sets the analysis value on the record to the subject's last recorded non-missing observation. Last Observed Value Imputation Technique C132342 C81224 Derivation Type LVPD Last Value Prior to Dosing A data derivation or imputation technique which sets the analysis value on the record to the subject's last observed value prior to the start of study treatment. Last Value Prior to Dosing Imputation Technique C82868 C81224 Derivation Type MAXIMUM Maximum A data derivation or imputation technique which sets the analysis value on the record to the subject's maximum value over a defined set of records. Maximum Value Derivation Technique C82867 C81224 Derivation Type MINIMUM Minimum A data derivation or imputation technique which sets the analysis value on the record to the subject's minimum value over a defined set of records. Minimum Value Derivation Technique C53331 C81224 Derivation Type ML Maximum Likelihood A data derivation or imputation technique which sets the analysis value on the record to the estimate that maximizes the probability of observing what has in fact been observed. Maximum Likelihood Estimation C81204 C81224 Derivation Type MOTH Mean of Other Group A data derivation or imputation technique which sets the analysis value on the record to the mean value from a comparator or reference group. Mean of Other Group Imputation Technique C81207 C81224 Derivation Type MOV Mean Observed Value in a Group A data derivation or imputation technique which sets the analysis value on the record to the mean value observed in a group of subjects. Mean Observed Value in a Group Imputation Technique C170545 C81224 Derivation Type PHANTOM Phantom Record A technique that creates a record with a missing analysis value when there is no observed record for a given analysis visit or analysis timepoint. Phantom Record Imputation Technique C81205 C81224 Derivation Type POCF Penultimate Observation Carried Forward A data derivation or imputation technique which sets the analysis value on the record to the subject's next-to-last non-missing value. Penultimate Observation Carried Forward Imputation Technique C81200 C81224 Derivation Type SOCF Screening Observation Carried Forward A data derivation or imputation technique which sets the analysis value on the record to the subject's non-missing screening observation. Screening Observation Carried Forward Imputation Technique C174264 C81224 Derivation Type ULOD Upper Limit of Detection A data derivation or imputation technique which sets the analysis value on the record to the upper limit of detection of a test. Upper Limit of Detection Imputation Technique C170544 C81224 Derivation Type ULOQ Upper Limit of Quantification A data derivation or imputation technique which sets the analysis value on the record to the upper limit of quantification of a test. Upper Limit of Quantification Derivation Technique C81203 C81224 Derivation Type WC Worst Case A data derivation or imputation technique which sets the analysis value on the record to the worst possible outcome. Worst Case Imputation Technique C132343 C81224 Derivation Type WOC Worst Observed Case A data derivation or imputation technique which sets the analysis value on the record to the worst recorded outcome within a subject. Worst Observed Case Imputation Technique C81199 C81224 Derivation Type WOCF Worst Observed Value Carried Forward A data derivation or imputation technique which sets the analysis value on the record to the subject's worst-case non-missing observation. Worst Observation Carried Forward Imputation Technique C81206 C81224 Derivation Type WOV Worst Observed Value in a Group A data derivation or imputation technique which sets the analysis value on the record to the worst value observed in a group of subjects. Worst Observed Value in a Group Imputation Technique C172334 No Generalized Anxiety Disorder - 7 Version 2 Questionnaire Parameter Code GAD02PC Generalized Anxiety Disorder - 7 Version 2 Questionnaire Parameter Code A parameter code codelist for the Generalized Anxiety Disorder - 7 Version 2 Questionnaire (GAD-7 V2) to support the calculation of total score in ADaM. CDISC ADaM Generalized Anxiety Disorder-7 Version 2 Questionnaire Parameter Code Terminology C172451 C172334 Generalized Anxiety Disorder - 7 Version 2 Questionnaire Parameter Code GAD02TS GAD02-Total Score - Analysis Generalized Anxiety Disorder - 7 Version 2 - Total score used for analysis. Generalized Anxiety Disorder - 7 Version 2 - Analysis C172335 No Generalized Anxiety Disorder - 7 Version 2 Questionnaire Parameter Name GAD02PN Generalized Anxiety Disorder - 7 Version 2 Questionnaire Parameter Name A parameter name codelist for the Generalized Anxiety Disorder - 7 Version 2 Questionnaire (GAD-7 V2) to support the calculation of total score in ADaM. CDISC ADaM Generalized Anxiety Disorder-7 Version 2 Questionnaire Parameter Name Terminology C172451 C172335 Generalized Anxiety Disorder - 7 Version 2 Questionnaire Parameter Name GAD02-Total Score - Analysis GAD02-Total Score - Analysis Generalized Anxiety Disorder - 7 Version 2 - Total score used for analysis. Generalized Anxiety Disorder - 7 Version 2 - Analysis C158114 No Geriatric Depression Scale Short Form Questionnaire Parameter Code GDS02PC Geriatric Depression Scale Short Form Questionnaire Parameter Code A parameter code codelist for the Geriatric Depression Scale Short Form questionnaire (GDS02) to support the calculation of total score in ADaM. CDISC ADaM Geriatric Depression Scale Short Form Questionnaire Parameter Code Terminology C158155 C158114 Geriatric Depression Scale Short Form Questionnaire Parameter Code GDS02TS GDS02-Total Score - Analysis Geriatric Depression Scale Short Form - Total score used for analysis. Geriatric Depression Scale Short Form - Total Score C158115 No Geriatric Depression Scale Short Form Questionnaire Parameter Name GDS02PN Geriatric Depression Scale Short Form Questionnaire Parameter Name A parameter name codelist for the Geriatric Depression Scale Short Form questionnaire (GDS02) to support the calculation of total score in ADaM. CDISC ADaM Geriatric Depression Scale Short Form Questionnaire Parameter Name Terminology C158155 C158115 Geriatric Depression Scale Short Form Questionnaire Parameter Name GDS02-Total Score - Analysis GDS02-Total Score - Analysis Geriatric Depression Scale Short Form - Total score used for analysis. Geriatric Depression Scale Short Form - Total Score C81225 No Parameter Type PARAMTYP Parameter Type Parameter Type: Indicates whether the parameter is derived as a function of one or more other parameters. CDISC ADaM Parameter Type Terminology C81197 C81225 Parameter Type DERIVED Derived: Indicates that a parameter is derived as a function of one or more other parameters. Derived Flag C165644 Yes Pool for Integration POOLINT Pool for Integration Terminology relevant to the name of the Pool, often defined in the integrated statistical analysis plan, which identifies the combination of subjects' clinical trial experience and will be the focus of the integrated analysis. CDISC ADaM Pool for Integration Terminology C165858 C165644 Pool for Integration OVERALL The pool that includes data across all studies within which the subject has participated, used for the overall integrated analysis. Overall Pooled Data C124296 Yes Subject Trial Status SBJTSTAT Subject Trial Status Indicates the status of the subject in the trial. CDISC ADaM Subject Trial Status Terminology C25250 C124296 Subject Trial Status COMPLETED To possess every necessary or normal part or component or step; having come or been brought to a conclusion. (NCI) Complete C25484 C124296 Subject Trial Status DISCONTINUED To stop or end, permanently or temporarily. Discontinue C53279 C124296 Subject Trial Status ONGOING Continuous Remain in force or carry on without letup; keep or maintain in unaltered condition; exist in time or space without stop or interruption. (NCI) Continue C81226 No Time Imputation Flag TIMEFL Time Imputation Flag Time Imputation Flag: Indicates the level of imputation reflected in a time value. CDISC ADaM Time Imputation Flag Terminology C81213 C81226 Time Imputation Flag H Hours Imputed: Entire time (hours, minutes and seconds) is imputed. Hours Minutes Seconds Imputed C81214 C81226 Time Imputation Flag M Minutes Imputed: Minutes and seconds are imputed. Minutes Seconds Imputed C81215 C81226 Time Imputation Flag S Seconds Imputed: Seconds are imputed. Seconds Imputed